LOCUS       DAVLHM010000001       119223 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLHM010000001 DAVLHM010000000
VERSION     DAVLHM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 119223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 119223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..119223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.001"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..239)
                     /locus_tag="VXE45_000001"
     CDS             complement(<1..239)
                     /locus_tag="VXE45_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788118.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRR"
     gene            855..1373
                     /locus_tag="VXE45_000002"
     CDS             855..1373
                     /locus_tag="VXE45_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0788119.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            1503..2009
                     /locus_tag="VXE45_000003"
     CDS             1503..2009
                     /locus_tag="VXE45_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0788120.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            2009..2179
                     /locus_tag="VXE45_000004"
     CDS             2009..2179
                     /locus_tag="VXE45_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788121.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            2211..3443
                     /gene="clpX"
                     /locus_tag="VXE45_000005"
     CDS             2211..3443
                     /gene="clpX"
                     /locus_tag="VXE45_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0788122.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            3452..4039
                     /locus_tag="VXE45_000006"
     CDS             3452..4039
                     /locus_tag="VXE45_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0788123.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            4050..4430
                     /locus_tag="VXE45_000007"
     CDS             4050..4430
                     /locus_tag="VXE45_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0788124.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            4482..5372
                     /gene="rapZ"
                     /locus_tag="VXE45_000008"
     CDS             4482..5372
                     /gene="rapZ"
                     /locus_tag="VXE45_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0788125.1"
                     /translation="MTKKQFHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            5369..6346
                     /locus_tag="VXE45_000009"
     CDS             5369..6346
                     /locus_tag="VXE45_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0788126.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            6343..7254
                     /gene="whiA"
                     /locus_tag="VXE45_000010"
     CDS             6343..7254
                     /gene="whiA"
                     /locus_tag="VXE45_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0788127.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(7342..8469)
                     /locus_tag="VXE45_000011"
     CDS             complement(7342..8469)
                     /locus_tag="VXE45_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0788128.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESD
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(8748..9698)
                     /locus_tag="VXE45_000012"
     CDS             complement(8748..9698)
                     /locus_tag="VXE45_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEV0788129.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            complement(9847..10638)
                     /locus_tag="VXE45_000013"
     CDS             complement(9847..10638)
                     /locus_tag="VXE45_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0788130.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAIIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            complement(10882..11571)
                     /locus_tag="VXE45_000014"
     CDS             complement(10882..11571)
                     /locus_tag="VXE45_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV0788131.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            11778..11942
                     /locus_tag="VXE45_000015"
     CDS             11778..11942
                     /locus_tag="VXE45_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788132.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            11961..12176
                     /locus_tag="VXE45_000016"
     CDS             11961..12176
                     /locus_tag="VXE45_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0788133.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            12208..12408
                     /locus_tag="VXE45_000017"
     CDS             12208..12408
                     /locus_tag="VXE45_000017"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788134.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(12807..12998)
                     /locus_tag="VXE45_000018"
     CDS             complement(12807..12998)
                     /locus_tag="VXE45_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788135.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            13117..13260
                     /locus_tag="VXE45_000019"
     CDS             13117..13260
                     /locus_tag="VXE45_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788136.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            13257..13427
                     /locus_tag="VXE45_000020"
     CDS             13257..13427
                     /locus_tag="VXE45_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788137.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(13420..13659)
                     /locus_tag="VXE45_000021"
     CDS             complement(13420..13659)
                     /locus_tag="VXE45_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788138.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            13777..14049
                     /locus_tag="VXE45_000022"
     CDS             13777..14049
                     /locus_tag="VXE45_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788139.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            14046..14261
                     /locus_tag="VXE45_000023"
     CDS             14046..14261
                     /locus_tag="VXE45_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788140.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            14240..14428
                     /locus_tag="VXE45_000024"
     CDS             14240..14428
                     /locus_tag="VXE45_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788141.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            14440..14781
                     /locus_tag="VXE45_000025"
     CDS             14440..14781
                     /locus_tag="VXE45_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788142.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            14782..15012
                     /locus_tag="VXE45_000026"
     CDS             14782..15012
                     /locus_tag="VXE45_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788143.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELHRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            15026..15748
                     /locus_tag="VXE45_000027"
     CDS             15026..15748
                     /locus_tag="VXE45_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0788144.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            15741..16223
                     /locus_tag="VXE45_000028"
     CDS             15741..16223
                     /locus_tag="VXE45_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV0788145.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            16223..16582
                     /locus_tag="VXE45_000029"
     CDS             16223..16582
                     /locus_tag="VXE45_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788146.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            16582..17067
                     /locus_tag="VXE45_000030"
     CDS             16582..17067
                     /locus_tag="VXE45_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788147.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            17030..18223
                     /locus_tag="VXE45_000031"
     CDS             17030..18223
                     /locus_tag="VXE45_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV0788148.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            18241..18558
                     /locus_tag="VXE45_000032"
     CDS             18241..18558
                     /locus_tag="VXE45_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788149.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            18558..19385
                     /locus_tag="VXE45_000033"
     CDS             18558..19385
                     /locus_tag="VXE45_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0788150.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            19405..19908
                     /locus_tag="VXE45_000034"
     CDS             19405..19908
                     /locus_tag="VXE45_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788151.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DEDDLPF"
     gene            20081..20902
                     /locus_tag="VXE45_000035"
     CDS             20081..20902
                     /locus_tag="VXE45_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV0788152.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            20905..22248
                     /locus_tag="VXE45_000036"
     CDS             20905..22248
                     /locus_tag="VXE45_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0788153.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSSQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            22541..22696
                     /locus_tag="VXE45_000037"
     CDS             22541..22696
                     /locus_tag="VXE45_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788154.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            22693..23388
                     /locus_tag="VXE45_000038"
     CDS             22693..23388
                     /locus_tag="VXE45_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0788155.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREFWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELENAKIGW
                     VFDCEGFEIEEVE"
     gene            23546..23806
                     /locus_tag="VXE45_000039"
     CDS             23546..23806
                     /locus_tag="VXE45_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV0788156.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            23806..24264
                     /locus_tag="VXE45_000040"
     CDS             23806..24264
                     /locus_tag="VXE45_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788157.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            24312..24380
                     /locus_tag="VXE45_000041"
                     /pseudo
     CDS             24312..24380
                     /locus_tag="VXE45_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            24377..24814
                     /locus_tag="VXE45_000042"
     CDS             24377..24814
                     /locus_tag="VXE45_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788158.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            24811..25182
                     /locus_tag="VXE45_000043"
     CDS             24811..25182
                     /locus_tag="VXE45_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788159.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            25255..25659
                     /locus_tag="VXE45_000044"
     CDS             25255..25659
                     /locus_tag="VXE45_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0788160.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            25740..25822
                     /locus_tag="VXE45_000045"
     tRNA            25740..25822
                     /locus_tag="VXE45_000045"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25771..25773,aa:Tyr,seq:gta)
     gene            26089..26568
                     /locus_tag="VXE45_000046"
     CDS             26089..26568
                     /locus_tag="VXE45_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0788161.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDISD"
     gene            26546..27844
                     /locus_tag="VXE45_000047"
     CDS             26546..27844
                     /locus_tag="VXE45_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0788162.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            27856..29325
                     /locus_tag="VXE45_000048"
     CDS             27856..29325
                     /locus_tag="VXE45_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0788163.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            29234..30265
                     /locus_tag="VXE45_000049"
                     /pseudo
     CDS             29234..30265
                     /locus_tag="VXE45_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            30625..30852
                     /locus_tag="VXE45_000050"
     CDS             30625..30852
                     /locus_tag="VXE45_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HEV0788164.1"
                     /translation="MAILDDLQALYDNGWDASFNYNGQVCGIFPNSIYDVVVIIADDE
                     YRASSFDDLISLQIEGKTLPEIMNEVEVQYG"
     gene            31001..31213
                     /locus_tag="VXE45_000051"
     CDS             31001..31213
                     /locus_tag="VXE45_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788165.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDS
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            31383..31967
                     /locus_tag="VXE45_000052"
     CDS             31383..31967
                     /locus_tag="VXE45_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0788166.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            31974..32819
                     /locus_tag="VXE45_000053"
     CDS             31974..32819
                     /locus_tag="VXE45_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0788167.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            32831..33013
                     /locus_tag="VXE45_000054"
     CDS             32831..33013
                     /locus_tag="VXE45_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0788168.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            33003..33191
                     /locus_tag="VXE45_000055"
     CDS             33003..33191
                     /locus_tag="VXE45_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788169.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            33193..33504
                     /locus_tag="VXE45_000056"
     CDS             33193..33504
                     /locus_tag="VXE45_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0788170.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            33485..33823
                     /locus_tag="VXE45_000057"
     CDS             33485..33823
                     /locus_tag="VXE45_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788171.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            33798..34313
                     /locus_tag="VXE45_000058"
     CDS             33798..34313
                     /locus_tag="VXE45_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0788172.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            34310..34678
                     /locus_tag="VXE45_000059"
     CDS             34310..34678
                     /locus_tag="VXE45_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788173.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            34681..35094
                     /locus_tag="VXE45_000060"
     CDS             34681..35094
                     /locus_tag="VXE45_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0788174.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            35099..35479
                     /locus_tag="VXE45_000061"
     CDS             35099..35479
                     /locus_tag="VXE45_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788175.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            35518..35868
                     /locus_tag="VXE45_000062"
     CDS             35518..35868
                     /locus_tag="VXE45_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788176.1"
                     /translation="MFLDIEGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            35855..39508
                     /locus_tag="VXE45_000063"
     CDS             35855..39508
                     /locus_tag="VXE45_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788177.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNDFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            39517..39867
                     /locus_tag="VXE45_000064"
     CDS             39517..39867
                     /locus_tag="VXE45_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788178.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            39872..45487
                     /locus_tag="VXE45_000065"
     CDS             39872..45487
                     /locus_tag="VXE45_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0788179.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQA
                     SGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGYNALKIIGLNPSGRDGGNPK
                     VTYPVLGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIK
                     RYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQI
                     STVESTFKQRVNSLEAGVNRLTEGLRTKADISALNVTAENIRQSVKSLETDTQNKLNQ
                     KLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKT
                     VGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQG
                     RNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQ
                     LKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDGENELLVAKTEFKRTADGL
                     STKMAAVESYVGQDGQRQEALQRYTREESTRQATAVRELVNRDFVGKATYQEDVKGIN
                     QRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSE
                     QGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANAD
                     SQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEV
                     GKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFL
                     YSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTS
                     RCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVA
                     DANKKLEATQTKMTQLAGSWVVENINSAGDIISGINLGANGHNRFVGKLTHITGETLI
                     DRAVIKSAMVDKLKTGNFEAGSVTTTILDAEAVTAEKLKVDDALIRKLTANDAFIDRL
                     TSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAG
                     HGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTT
                     FSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKEN
                     ITDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLH
                     IDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            45582..45785
                     /locus_tag="VXE45_000066"
     CDS             45582..45785
                     /locus_tag="VXE45_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788180.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITNNILSIQLDEQREGNQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            45788..46138
                     /locus_tag="VXE45_000067"
     CDS             45788..46138
                     /locus_tag="VXE45_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788181.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            46148..46447
                     /locus_tag="VXE45_000068"
     CDS             46148..46447
                     /locus_tag="VXE45_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788182.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            46451..46783
                     /locus_tag="VXE45_000069"
     CDS             46451..46783
                     /locus_tag="VXE45_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0788183.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            46787..47743
                     /locus_tag="VXE45_000070"
     CDS             46787..47743
                     /locus_tag="VXE45_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0788184.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(47995..48963)
                     /locus_tag="VXE45_000071"
     CDS             complement(47995..48963)
                     /locus_tag="VXE45_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0788185.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFVPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            49099..49956
                     /locus_tag="VXE45_000072"
     CDS             49099..49956
                     /locus_tag="VXE45_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0788186.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            49943..50722
                     /locus_tag="VXE45_000073"
     CDS             49943..50722
                     /locus_tag="VXE45_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0788187.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            50746..52098
                     /locus_tag="VXE45_000074"
     CDS             50746..52098
                     /locus_tag="VXE45_000074"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0788188.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            52172..52546
                     /locus_tag="VXE45_000075"
     CDS             52172..52546
                     /locus_tag="VXE45_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0788189.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            52548..53396
                     /locus_tag="VXE45_000076"
     CDS             52548..53396
                     /locus_tag="VXE45_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0788190.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASEFPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            53673..54440
                     /locus_tag="VXE45_000077"
     CDS             53673..54440
                     /locus_tag="VXE45_000077"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0788191.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            54452..55636
                     /locus_tag="VXE45_000078"
     CDS             54452..55636
                     /locus_tag="VXE45_000078"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0788192.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            55633..57504
                     /locus_tag="VXE45_000079"
     CDS             55633..57504
                     /locus_tag="VXE45_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0788193.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLTTLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(57647..58831)
                     /gene="mntE"
                     /locus_tag="VXE45_000080"
     CDS             complement(57647..58831)
                     /gene="mntE"
                     /locus_tag="VXE45_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0788194.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            59135..61831
                     /locus_tag="VXE45_000081"
     CDS             59135..61831
                     /locus_tag="VXE45_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0788195.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            61844..62635
                     /gene="yghU"
                     /locus_tag="VXE45_000082"
     CDS             61844..62635
                     /gene="yghU"
                     /locus_tag="VXE45_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0788196.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTESVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            62751..63161
                     /locus_tag="VXE45_000083"
     CDS             62751..63161
                     /locus_tag="VXE45_000083"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0788197.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            63173..64768
                     /locus_tag="VXE45_000084"
     CDS             63173..64768
                     /locus_tag="VXE45_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788198.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            64835..64999
                     /locus_tag="VXE45_000085"
     CDS             64835..64999
                     /locus_tag="VXE45_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0788199.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            65078..65806
                     /gene="yaaA"
                     /locus_tag="VXE45_000086"
     CDS             65078..65806
                     /gene="yaaA"
                     /locus_tag="VXE45_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0788200.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(66083..66631)
                     /locus_tag="VXE45_000087"
     CDS             complement(66083..66631)
                     /locus_tag="VXE45_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0788201.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            66952..67440
                     /locus_tag="VXE45_000088"
     CDS             66952..67440
                     /locus_tag="VXE45_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0788202.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            67437..68624
                     /locus_tag="VXE45_000089"
     CDS             67437..68624
                     /locus_tag="VXE45_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0788203.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            68617..68982
                     /locus_tag="VXE45_000090"
     CDS             68617..68982
                     /locus_tag="VXE45_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0788204.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            68998..70344
                     /gene="asnS"
                     /locus_tag="VXE45_000091"
     CDS             68998..70344
                     /gene="asnS"
                     /locus_tag="VXE45_000091"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0788205.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVKNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            70497..70787
                     /locus_tag="VXE45_000092"
     CDS             70497..70787
                     /locus_tag="VXE45_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0788206.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            70799..71269
                     /gene="ssbA"
                     /locus_tag="VXE45_000093"
     CDS             70799..71269
                     /gene="ssbA"
                     /locus_tag="VXE45_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0788207.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            71301..71540
                     /locus_tag="VXE45_000094"
     CDS             71301..71540
                     /locus_tag="VXE45_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0788208.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            71835..73235
                     /locus_tag="VXE45_000095"
     CDS             71835..73235
                     /locus_tag="VXE45_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0788209.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSIRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            73237..73596
                     /locus_tag="VXE45_000096"
     CDS             73237..73596
                     /locus_tag="VXE45_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0788210.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEKKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            73650..74399
                     /locus_tag="VXE45_000097"
     CDS             73650..74399
                     /locus_tag="VXE45_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0788211.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            74389..74688
                     /locus_tag="VXE45_000098"
     CDS             74389..74688
                     /locus_tag="VXE45_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0788212.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            74759..75694
                     /locus_tag="VXE45_000099"
     CDS             74759..75694
                     /locus_tag="VXE45_000099"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0788213.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRIITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            75780..76292
                     /locus_tag="VXE45_000100"
     CDS             75780..76292
                     /locus_tag="VXE45_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0788214.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            76317..76925
                     /locus_tag="VXE45_000101"
     CDS             76317..76925
                     /locus_tag="VXE45_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0788215.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            77026..77220
                     /locus_tag="VXE45_000102"
     CDS             77026..77220
                     /locus_tag="VXE45_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0788216.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(77266..78711)
                     /locus_tag="VXE45_000103"
     CDS             complement(77266..78711)
                     /locus_tag="VXE45_000103"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0788217.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMEKSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            78817..80439
                     /locus_tag="VXE45_000104"
     CDS             78817..80439
                     /locus_tag="VXE45_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0788218.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            80642..82600
                     /locus_tag="VXE45_000105"
     CDS             80642..82600
                     /locus_tag="VXE45_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0788219.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            82772..83707
                     /locus_tag="VXE45_000106"
     CDS             82772..83707
                     /locus_tag="VXE45_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788220.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSRSKGSSVALENLLAVPKEKFE"
     gene            83732..84454
                     /locus_tag="VXE45_000107"
     CDS             83732..84454
                     /locus_tag="VXE45_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0788221.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGYILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDESTANLDADSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEGGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            84612..85706
                     /locus_tag="VXE45_000108"
     CDS             84612..85706
                     /locus_tag="VXE45_000108"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0788222.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            85714..86880
                     /locus_tag="VXE45_000109"
     CDS             85714..86880
                     /locus_tag="VXE45_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0788223.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVVTFAKR"
     gene            86973..90071
                     /locus_tag="VXE45_000110"
     CDS             86973..90071
                     /locus_tag="VXE45_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0788224.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVVVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            90119..90736
                     /locus_tag="VXE45_000111"
     CDS             90119..90736
                     /locus_tag="VXE45_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0788225.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVQPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            90747..92081
                     /locus_tag="VXE45_000112"
     CDS             90747..92081
                     /locus_tag="VXE45_000112"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0788226.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            92091..92555
                     /locus_tag="VXE45_000113"
     CDS             92091..92555
                     /locus_tag="VXE45_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788227.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            92552..93046
                     /locus_tag="VXE45_000114"
     CDS             92552..93046
                     /locus_tag="VXE45_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788228.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            93127..94782
                     /gene="mltG"
                     /locus_tag="VXE45_000115"
     CDS             93127..94782
                     /gene="mltG"
                     /locus_tag="VXE45_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0788229.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGSETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            94853..95335
                     /gene="greA"
                     /locus_tag="VXE45_000116"
     CDS             94853..95335
                     /gene="greA"
                     /locus_tag="VXE45_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0788230.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            95617..96015
                     /locus_tag="VXE45_000117"
     CDS             95617..96015
                     /locus_tag="VXE45_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788231.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAL
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            96436..97443
                     /locus_tag="VXE45_000118"
                     /pseudo
     CDS             96436..97443
                     /locus_tag="VXE45_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            97518..97718
                     /locus_tag="VXE45_000119"
     CDS             97518..97718
                     /locus_tag="VXE45_000119"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0788232.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            97753..98469
                     /gene="atpB"
                     /locus_tag="VXE45_000120"
     CDS             97753..98469
                     /gene="atpB"
                     /locus_tag="VXE45_000120"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0788233.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            98483..98977
                     /gene="atpF"
                     /locus_tag="VXE45_000121"
     CDS             98483..98977
                     /gene="atpF"
                     /locus_tag="VXE45_000121"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0788234.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            98977..99513
                     /locus_tag="VXE45_000122"
     CDS             98977..99513
                     /locus_tag="VXE45_000122"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0788235.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            99528..101033
                     /locus_tag="VXE45_000123"
     CDS             99528..101033
                     /locus_tag="VXE45_000123"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0788236.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            101049..101927
                     /locus_tag="VXE45_000124"
     CDS             101049..101927
                     /locus_tag="VXE45_000124"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0788237.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            102013..103419
                     /gene="atpD"
                     /locus_tag="VXE45_000125"
     CDS             102013..103419
                     /gene="atpD"
                     /locus_tag="VXE45_000125"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0788238.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            103430..103849
                     /locus_tag="VXE45_000126"
     CDS             103430..103849
                     /locus_tag="VXE45_000126"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0788239.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(103894..104907)
                     /locus_tag="VXE45_000127"
     CDS             complement(103894..104907)
                     /locus_tag="VXE45_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0788240.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            105051..106217
                     /locus_tag="VXE45_000128"
     CDS             105051..106217
                     /locus_tag="VXE45_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0788241.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            106207..107436
                     /locus_tag="VXE45_000129"
     CDS             106207..107436
                     /locus_tag="VXE45_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0788242.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            107582..108223
                     /locus_tag="VXE45_000130"
     CDS             107582..108223
                     /locus_tag="VXE45_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0788243.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            108233..108862
                     /locus_tag="VXE45_000131"
     CDS             108233..108862
                     /locus_tag="VXE45_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0788244.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            108875..109711
                     /locus_tag="VXE45_000132"
     CDS             108875..109711
                     /locus_tag="VXE45_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0788245.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(109990..110337)
                     /locus_tag="VXE45_000133"
     CDS             complement(109990..110337)
                     /locus_tag="VXE45_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0788246.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(110448..112166)
                     /locus_tag="VXE45_000134"
     CDS             complement(110448..112166)
                     /locus_tag="VXE45_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0788247.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            112400..112725
                     /locus_tag="VXE45_000135"
                     /pseudo
     CDS             112400..112725
                     /locus_tag="VXE45_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            112798..113244
                     /locus_tag="VXE45_000136"
     CDS             112798..113244
                     /locus_tag="VXE45_000136"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788248.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERISIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            113584..113838
                     /locus_tag="VXE45_000137"
     CDS             113584..113838
                     /locus_tag="VXE45_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788249.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            113949..115055
                     /locus_tag="VXE45_000138"
     CDS             113949..115055
                     /locus_tag="VXE45_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0788250.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            115013..115621
                     /locus_tag="VXE45_000139"
     CDS             115013..115621
                     /locus_tag="VXE45_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0788251.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            115845..116714
                     /locus_tag="VXE45_000140"
     CDS             115845..116714
                     /locus_tag="VXE45_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0788252.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            117625..118821
                     /gene="tuf"
                     /locus_tag="VXE45_000141"
     CDS             117625..118821
                     /gene="tuf"
                     /locus_tag="VXE45_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0788253.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
BASE COUNT        36792 a        21700 c        26780 g        33951 t
ORIGIN      
        1 aagcgacgct ttctaaggag gattctagta ggcataccag tcgtttcaag ataaggaatc
       61 ttagacggtt tttgaaagtc atatttcttc atttgacttc cgcactcagg gcaagatgga
      121 gcctcataat ccagcttagc gataatttct ttgtgggtat ccatattgat gatatctaga
      181 atcttgatgt ttgggtcttt aatatcgagc agttttgtga taaaatgtaa ttgttccata
      241 tgaatctttc taatgatggt tttgtcgctt ttcattatag gtcatatggg actttttttc
      301 tacaataaaa taggctccat aatatctata gtggatttac ccactacaaa tattatagag
      361 cctgatttga aagagggatg tgatagtagc accctctttt tctttgtttt atgatagttc
      421 atcctcgagt aaattcaaga tcttgctcgg aaatgaagct tatatagtag attgaatata
      481 gacaaagacc ttgtgattgg taaaacattt tagaaattca tttacctttc ctaatcgact
      541 tggtttcatc ttatttcaat ctattatagt attggggaat ttcttcaaac cacatcagct
      601 tggtcagttc tacctgcgac ctcaaaactt gtgctttggt caagctgggt ttagtttcct
      661 agtttgctga tggatttcca ttgactataa gcatccaacc ctcttttttg tcttctaaag
      721 aattcttaaa ttatcagtct attgcaactt ttctcatata agttctttgt cttgctattg
      781 gttttcctta gtagtatact aaggtagtaa tcattaagaa gtggttacaa aaaataatga
      841 atgaggtaaa gaaaatggta gaattgaaaa aagaagcagt aaaagacgta acatcattga
      901 caaaagcagc gccagtagca ttggcaaaaa caaaggaagt cttgaaccaa gctgttgctg
      961 atttgtatgt agctcacgtt gctttgcacc aagtgcactg gtatatgcat ggtcgtggtt
     1021 tccttgtatg gcatccaaaa atggatgagt acatggaagc tcttgacggt caattggatg
     1081 aaatcagcga acgcttgatt acactcggtg gaagcccatt ctctacattg acagagttcc
     1141 ttcaaaatag tgaaatcgaa gaagaagctg gtgaataccg taatgttgaa gaaagcttgg
     1201 aacgtgttct tgttatctac cgttacttgt cagaactttt ccaaaaaggt ttggatgtca
     1261 ctgatgaaga aggtgacgat gtaacaaacg gtatctttgc aggcgctaaa actgaaacag
     1321 ataaaacaat ttggatgctt gcagccgaac ttggacaagc acctggtttg taagaaataa
     1381 ggaaacatag ataaatctgt aggaaatttc ttacagattt tttctatttt gtaagctatt
     1441 ccaaaccagt ctttttttga gttttttgat aaaatagtac tatcagtgaa aaggatggaa
     1501 gcatgactaa gaaaatcgta gctatttggg cccaggatga agagggtgtg attggtaagg
     1561 aaaatcgtct gccttggcat ttgccagcag aattgcagca ctttaaagaa acaactctga
     1621 atcatgctat cttgatgggg cgtgtgacct ttgatgggat ggggcgtcgc ttgcttccaa
     1681 aacgggaaac cctgattttg acgcgtaatc cggaagaaaa gatagatggg gttgctactt
     1741 ttcaggacgt ccagtctgtt cttgactggt atcaggatca agaaaagaat ctctacatta
     1801 tcggtgggaa gcaaattttt caggcttttg aaccttacct tgatgaagtg attgtcactc
     1861 acattcatgc tcgggtggaa ggagatacct atttccctga agagcttgac ttgtctcttt
     1921 ttgagacagt ttcaagcaaa ttttacgcca aagatgagaa gaatccttat gattttacca
     1981 tccaataccg caagagaaag gaagtctaat ggaacggagt ttatttggtc tattcacggc
     2041 ttttctgtgt ttcatctgct ttctggcagg agcacaggct tttcgtaaaa agcgttacgg
     2101 gctttctatc ctcctttggt taaatgcctt taccaatctg gtcaatagta ttcatgcttt
     2161 ttacatgacc ttattttaga tagaatgaca gtatagaatg gaaggaaatc atgtctacaa
     2221 atagaaaaaa tgatatgatg gtttattgct cattttgtgg caaaaaccaa gaagaagtac
     2281 aaaaaataat tgctggcaac aatgctttta tttgtaatga atgcgtggag ttagctcagg
     2341 aaatcattcg agaagaattg gttgaggaag tcttggcaga cttgtctgag gtgccaaaac
     2401 caattgaact cctccatatc ttgaaccact atgtaattgg tcaagatcgt gccaagcgtg
     2461 ccttggcagt ggcggtttat aaccactaca aacgcatcaa tttccacgat acacgcgaag
     2521 agtcagaaga tgtggatttg cagaagtcaa acattttgat gattggccca actggttcag
     2581 ggaaaacttt ccttgcccag accttggcta agagcttgaa tgtgcctttt gctattgcgg
     2641 atgcgacagc tctgacggag gctggttatg tgggtgagga cgtggaaaat atcctcctca
     2701 aactcttgca ggttgctgac tttaacatcg aacgtgcaga gcgtggcatt atctatgtgg
     2761 atgaaattga caagattgcc aagaagagtg agaatgtgtc tatcacacgt gatgtttctg
     2821 gtgaaggggt gcaacaagcc cttctcaaga ttatcgaggg aactgttgct agcgtgccgc
     2881 ctcaaggtgg acgcaaacat ccacaacaag agatgattca agtggataca aaaaatatcc
     2941 tcttcatcgt gggtggtgct tttgatggta ttgaagaaat tgtcaaacaa cgtctgggtg
     3001 aaaaagtcat cggatttggt caaaataata aggcgattga cgaaaacagc tcatatatgc
     3061 aagaaatcat cgctgaagac attcaaaaat ttggtattat ccctgagttg attggacgct
     3121 tgcctgtttt tgcggctctt gagcaattga ccgttgatga cttggttcgc atcttgaaag
     3181 agccaagaaa tgccttggtg aaacaatacc aaactttgct ttcttatgat gatgttgagt
     3241 tggaatttga cgacgaagcc cttcaagaga ttgctaataa agcaatcgaa cggaagacag
     3301 gggcgcgtgg acttcgctcc attatcgaag aaaccatgct agatgttatg tttgaggtgc
     3361 cgagtcagga aaatgtgaaa ttggttcgca tcactaaaga aactgtcgat ggaacggata
     3421 aaccgatcct agaaacagcc tagaggtgac tatggaactt aatacacaca atgctgaaat
     3481 cttgctcagt gcagctaata agtcccacta tccgcaggat gaactgccag agattgccct
     3541 agcagggcgt tcaaatgttg gtaaatccag ctttatcaac actatgttga accgtaagaa
     3601 tctcgcccgt acatcaggaa aacctggtaa aacccagctc ctgaactttt ttaacattga
     3661 tgacaagatg cgctttgtgg atgtgcctgg ttatggctat gctcgtgttt ctaaaaagga
     3721 acgtgaaaag tgggggtgca tgattgagga gtacttaacg actcgggaaa atctccgtgc
     3781 ggttgtcagt ctagttgacc ttcgtcatga cccgtcagca gatgatgtgc agatgtacga
     3841 atttctcaag tattatgaga ttccagtcat cattgtggcg accaaggcgg acaagattcc
     3901 tcgtggtaaa tggaacaagc atgaatcagc aatcaaaaag aaattaaact ttgacccgag
     3961 tgacgatttc atcctctttt catctgtcag caaggcaggg atggatgagg cttgggatgc
     4021 aatcttagaa aaattgtgag gaaaagaaaa tggcaaaaac aattcataca gataaggccc
     4081 caaaggctat cggaccctat gttcaaggaa aaatcgttgg caaccttttg tttgctagcg
     4141 gtcaagttcc cctatcccct gaaactgggg aaattgtagg agagaatatc caagaacaga
     4201 cagagcaagt cttgaaaaac atcggtgcta ttttggcaga agcaggaaca gactttgacc
     4261 atgttgtcaa aacaacttgc ttcttgagcg atatgaacga ctttgttcct tttaatgagg
     4321 tttaccaaac ggccttcaaa gaggaattcc cagctcgttc agctgtggag gtagctcgtc
     4381 ttcctcgtga tgtaaaagtc gaaattgaag tcatcgcaga gattggataa gctagttgaa
     4441 gtttggtgtt gccaaacttc ttttgatata aggagaaaaa gatgacaaag aaacaatttc
     4501 acttggtgat tgtgacaggg atgagtggcg cagggaaaac tgtagccatt cagtccttcg
     4561 aggatctagg ttatttcacc attgataata tgccgccagc tctcttgcct aagtttttgc
     4621 agctggttga aattaaggaa gacaatccta agttggcctt ggtagtggat atgcgtagcc
     4681 gttctttctt ttcagagatt caagctgttt tggatgagtt ggaaaatcaa gatggtttgg
     4741 atttcaaaat cctctttttg gatgcggctg ataaggaatt ggtcgctcgt tacaaggaaa
     4801 ccagacggag tcacccacta gcagcagacg gtcgtatttt agatggaatc aagttggaac
     4861 gtgaactctt ggcacctttg aaaaatatga gccaaaatgt ggtggatacg actgaactca
     4921 ctccacgtga gctgcgcaaa acccttgcag agcagttttc agaccaagaa caagcccagt
     4981 ctttccgtat cgaagtcatg tctttcggat ttaagtatgg aatcccgatt gatgcggact
     5041 tggtctttga tgtccgtttc ttgccaaatc cctattatct accagaactg agaaaccaaa
     5101 cgggtgtgga tgaacctgtt tatgattatg tcatgaacca tcctgagtca gaagactttt
     5161 atcaacattt attggccttg attgagccga ttctgccaag ttaccaaaag gaaggtaagt
     5221 ccgttttgac cattgccatg ggatgtacgg gtggacaaca ccgtagtgtg gcatttgcta
     5281 aacgcttggc gcaggactta tccaagaatt ggtctgttaa tgaagggcat cgcgacaaag
     5341 accgcagaaa ggaaacggta aaccgttcat gagaaaacca aagataacgg tgattggtgg
     5401 agggactgga attcccgtca ttctaaaaag tctgcgggaa aaagatgtgg aaatcgcagc
     5461 tatcgtgacg gtggcagatg atggtggttc ttcaggtgaa ctccgaaaaa atatgcaaca
     5521 gttgacaccg ccaggtgatc ttcgtaatgt ccttgtggcc atgtcggata tgcctaagtt
     5581 ttatgagaag gtctttcagt atcggttctc tgaggatgcc ggagcctttg ctggccatcc
     5641 attgggaaat ctcatcattg ctggcttgtc agaaatgcag ggttcaacct ataatgccat
     5701 gcagttattg agcaaatttt tccatacaac agggaaaatt tatccttcca gtgaccatcc
     5761 tttgaccctt catgcagtct ttcaggatgg gacagaagtg gctggagaga gtcatattgt
     5821 agaccatcga ggcataattg acaatgtcta tgtgaccaat gccctaaacg atgatacgcc
     5881 tctggccagc cgtcgagtag tgcagaccat ccttgaaagt gacatgattg tcctagggcc
     5941 aggttccctc tttacctcta ttttgcccaa tatcgtgatt aaggaaattg ggcgggctct
     6001 tttggaaact aaggcagaaa ttgcctatgt ctgcaatatc atgacccaac gtggggagac
     6061 ggaacacttt acagatagcg accacgtgga agtcttgcat cgtcaccttg gtcgcccttt
     6121 tatcgacact gtcttggtga atattgaaaa agtgcctcag gaatacatga attccaaccg
     6181 ttttgatgaa tacttggtgc aagtggaaca cgattttgta ggtctttgta agcaagtttc
     6241 gcgcgtgatt tcatctaact tccttcgtct ggaaaatggc ggtgccttcc acgatggaga
     6301 tttgattgtg gacgagttga tgcgcattat acaggtgaaa aaatgagttt cacagtagca
     6361 gtaaaagaag aaatcctggg ccaacaccat ctgagctggc atgaattatc tgccattatc
     6421 aaaatgtctg gtagcatcgg tctctcgact tcgggcttga ctttgtcagt tgtgacagaa
     6481 aatgccaaac tggcccgtca cctctatgag tcctttctcc atttctatga aatcaaatct
     6541 gaaattcgtc accaccaacg gagcaatctt cgcaagaatc gcgtctatac cgtttttaca
     6601 gatgaaaagg tgcaggattt gttaagtgat ttgcacttgg cagactcttt ctttggcctg
     6661 gaaacaggta ttgatgaggc gattttatcg gatgaggaag caggtcgtgc ctatctctgt
     6721 ggcgctttct tggcaaatgg gagcattcgt gaccctgagt caggcaagta ccagttggaa
     6781 atcagttctg tttatctgga ccacgcgcaa ggaattgcct cccttctcca acagttttta
     6841 ctggatgcca aggtgcttga gcgcaagaag ggggctgtga cctatctcca gcgagcagaa
     6901 gacattatgg acttcttgat agtaatagga gccatgcagg cacgtgatga ttttgagcgg
     6961 gttaagattt tgcgagaaac ccgtaacgac ctcaatcggg ctaataatgc cgagacagct
     7021 aatatcgctc ggacagtttc tgccagcatg aagaccatta acaatatcag taaaatcaaa
     7081 gatatcatgg gcttagaaaa tttgccagta gatttgcagg aagtggcgca actgaggatt
     7141 cagcacccag actactctat ccagcagtta gcagatagtc tcagcacccc tctgaccaaa
     7201 agtggtgtca atcacagact cagaaaaatc aataagatag cggatgaatt ataacgatat
     7261 aaagcaaccc cttgaattat caatatcttc aaggggtttt gttgtgttat gaaatcaaaa
     7321 aggggcaatc aaggggcaga attaaaaaat agtatctaat ttattgacca gtttatcctc
     7381 catatcctca gtagtatgag aatagatttc caaagtcatt tttgcatttg agtgcccaac
     7441 tcgatccatt attgatttta ttgggaggtc agactctgct aaaaacgaaa tatgagaatg
     7501 cctaaaaata tggctagata agtttttttc tattttggcc tgttttccat atttttttaa
     7561 tatctgtatg aagcaagcta ttgttgtagg ttgattccat ttttcaaaac agaaaatata
     7621 atcatcgctt gacaatggct ggaaacgttc gctaagtcgt actatttgtc tttgaatagc
     7681 ttctatgaca ctctctgata ctttgattgt ccgtattgaa tttgtagtct ttggtagcgt
     7741 cttgattttg tttactgaat caaaattacc tgtgatctca attttgttgt tttcgaagtc
     7801 tatattcttc agttgtaagg cagttaactc accatatctc ataccagtta atgtcagcac
     7861 aagaaccata tcagcgtact tttggtgata ttctcgacga ttaaggacat cgacaagtgc
     7921 ttttatttct tgcatggtga gaaagttgtt acgctttttt tccagttctt ctaaagtctt
     7981 tggtttttga ggaatcgtag tataatcgac ctcgttgttt tcaatgtaag agtattgaac
     8041 agcgtaatta aagatacctc tgagcctatg ccgtactttt ttagctgtaa tatatccgtt
     8101 gctttcaata attttttcaa tagcctcttg aagaaaacgc ctgtcaagat tagcaagtat
     8161 ggtatcggat ggtatgactt ccttcatctt cttatcaact gatttacaat tatgttttgt
     8221 tgattccttt actgtttgcg cccatgattt atagaaaagg ttatagattt cttcaaatgt
     8281 aatgctttct acttgttttg tgctgagttt tttatttatc ttctcttgta acaagatagc
     8341 agcttgattt cttgcctggg gagttttctt ctccatggtt actgaaactt tttttaattt
     8401 ctcagtatat ggatctttat atcgctcaaa atatttaaat ttgccatttg gcaattcttc
     8461 catccacatt gcgtttacct cacttttttg ttaaaatggg tacaagaaaa ctaccttttt
     8521 aatggttgtt tcctatacat gatttcctca cactctcctt ggccaaaatt tgagtgtggg
     8581 gattttttgg ttgctatctc gtcagataat aaaataaggt gtacctctta gaagtacacc
     8641 agacgatttt atccttgacg aacaaggctt ttttacattc ttagtgtatt tcttttttta
     8701 atttctgtca agcagttatt tcctaaatgg aaatagttgg ttttaattta tacttttggt
     8761 tcattacggt gccaatcatt aggaaaacct aaagactggt tgattacatt gatgtctata
     8821 gaaggcagct ttttctctag tttgataact ttttttctaa gagtattcca caaaatgttg
     8881 aatgctgctt tactaataaa gcattgaagg ctaataattg ttgaatatac agtttttcta
     8941 ctgtcatctc ccatcaagat ctctttgtta tgaatcgttt cccaaaacgt actattagaa
     9001 cggcatctga agtttaataa gcgattattg tgagcgcatt tgtttcgtac ctcgttaata
     9061 ttttttagaa aagatatcaa ggtttctggt gggaaaacat cgttaaagtc aggtatgttt
     9121 gtgcttataa aacttactaa atcccgtgcg atttcatttt ggagtgaatt aggcaggttt
     9181 tcaataatcg tgcgtaaatc tccaaactct agataatcag ttagtaccca gattgggaca
     9241 tctgaatgag tatgtgcgta gtggtgaatt gaatttcctc tgtatcgctt gtttgtgttt
     9301 atgattttgg atagttttga tacaataaat cccacgtcta atattttatt atctgcataa
     9361 gaattggtgt ttaaataagc gtatttttga ctggggtaag cttcggcgaa tctgtgagca
     9421 gtgattgact tgatatggtg ttcagcttca agaatagctt gcaaaatggc tcgttttaca
     9481 tctttgtcaa atgtatagag acttgaaact tcgtcaaatg tgacgccgtc aatataagtg
     9541 tcagtaccag ggtgttgaaa aaacttactg tatccattga taatattgta gtaattgtta
     9601 cttagcaggt acttagctgc tttagattca tctgtaatgg ataaccctct gatttttagt
     9661 gttgcgattt gttcctcgat tgttttaaat ggcttcaaaa aaactccccc attctaattt
     9721 agaatgaagg agtttccccg tatcggtccc cgtagagatc ccgacgcttt ttctctaatg
     9781 aattcattct aaatgatttt tttaaaaaag tcaactgttt tttaatattt ttaaaaaata
     9841 atttttttat tcccctctat acaccccgac tactgcataa atcttgatgt gtgtgtcttc
     9901 ggctggtggg aagtctagga tgatgtcttc gtacttgtca ttgagtgaca ctaggcgtaa
     9961 gcgtccgttt tcggtatata tcttcttgaa gtaagaacgg tctccatatg cgataattgc
    10021 taaatctccg ttgtaggtag tcagtccttt gtctactaaa tagagaatgt ctccgtcttg
    10081 gtagtcgggt tgcatggagt ctccactgac cttggtcgca atatcgtggc gtggtggtcg
    10141 ctcgtcaacc tctatagtct ctctgtctgt atcgtcgtac ccaaatccat agttaaatcc
    10201 agaagctgct gccgtctcag atacaacctc aacttggtac aagctgataa cttccgatac
    10261 ttcgtttatc ttcgtttctt cttcgttttg gctctccaga agctcctcag aggtccgtag
    10321 cacgattttt tgattgggtg gggttaattg cactacctta tccattatct gctgtgtgag
    10381 cgaatctgga gcgtctggca gtgagttggt ggattcttct ttaaaagtag tatctatatc
    10441 tgatttttta acaccgaaat aatcagccag tttttggata acaccaaaag aaggagcgct
    10501 tcttaacttc atatagtctg tcatagtact tgctgtaatt ccaacttctt tagccaactc
    10561 tttttgggtg atgccacgtt gctttctaaa gtgtgtaata ttttcagcaa taatttgcat
    10621 tcgttttttt tcgtccattt acgattacct cgtatttttt ataattacat tatatatcat
    10681 ttttgaatga taaacaatca aaaatacgaa aaaatcctat ttttttgata aaaactattg
    10741 acaatacgaa aaaatcgtat tataattaaa tcaagcttaa ggaaaaggag gtaaggcaaa
    10801 tgaacgaact agaaagaaca gccctcaatg agatattgag gactgtgaca tatatagctg
    10861 agaagttgga tgaagtagat tctaagattt ctttgaacga ttcacaagct cttgagcatc
    10921 aaggaaattg agtttcattt ccatgtagtg aataactccg tgtaggtagt tctttaggtc
    10981 tgtaaaacct ttatcaggat tatttctata gtaatgacct tcgtcgttac cgatataagc
    11041 agatgcaagc gcaaatgttt taaggtcttc atccttgata tatttttcaa taacttgttt
    11101 taatgacatt ttaatgattt tatcttcatc atcaggattt gtaacaatgg agaaatcttt
    11161 aacaaagaac tcaagcgcct tacggtatcc aatacctgca atgtggtcta gttgttcgtg
    11221 ttcagctttc agtgcttgga catagatttg cttaccaatt ggagaaacta tctctacatc
    11281 gtcagatata ggtatatcgc tcggaagatt agggattact ttgatatgtt caatttcgta
    11341 tttttcggta tagtcattga ttaaaaatct tgtagctata aactcctctg tccaaaagtg
    11401 cttacaacct aagcatctac atgttaatac taagcttgtt ttattttctc caagagaaaa
    11461 ataagaagag ttcacaagat ctggattggt tggtttttta caatttgggc aaatgtcttc
    11521 aacggttaca ggcctagaaa cagaagaatt tactttcact cgaaatatca taagatttct
    11581 ccaatcgttt tattttgatt ataccatatt tgaaaggggg tgaggaaatg agaccaagac
    11641 gatatccgta tagtgggaaa aaagagtcca ccttcgtaaa ggcagaccct gagttaatgt
    11701 tgaatatcaa taagattgat gttggaaata tacaagcgaa aaatatattt ggaaaaattt
    11761 aaggagtagg aggatggatg aaagaaaata tagaacatct tcatgaacgc ataaagcatt
    11821 ttcagtcatt gattgcttat atgtctgagc atgagaaaaa gtattattta gaaaaagatt
    11881 ggttcgataa cccaacccta atttctatag aagacgcaaa aaaagaagta gaactacttt
    11941 aacagaaagg aggtaggaac gtgcagtgga ctttagaagc tatgagaatc aacaaaggac
    12001 ttactcaagc agagttggca gaaaaatttg aagtttcaag tcaaacaatt gctagattag
    12061 aaaaagatag ctctgatatc ggttatcagc tattgaaaaa atacatgttt tttttcaatg
    12121 tgaaattcga tgatattttt ttagggaaaa aatacgaaaa tttcgtaaat aactagaaac
    12181 aaaaaaataa gaaggaggaa cacatagatg gaaagcgttc ttgaaagctt gaaacaagaa
    12241 aaagaccacc tcgaaaaaat cattaaggta gttacctctg gtggtaaatt tctgagattg
    12301 ccgtatcaaa aaaagtcacg ctcgattagt gagaatctga aattgatttc tcaaaatctt
    12361 gataaattga gcgagcaagt tcaacaaacc acgaatcagc attcatgatt tcaagatgac
    12421 gaaagaaacc tgttttgatt tccagtttga tatcatgtta cagcgactcg ataaagcgat
    12481 tagtgattaa atttttgaga tgtaagtttt tttcatgtca aactttttca tgtcaaattt
    12541 tttacactaa taaatattaa ctaacaacaa gtattaaaag acaaccagtc ctacttctct
    12601 aaataaaaga gagggtagaa aaaataaata caaaggaggt gaggaaatga gaccaagacg
    12661 atatccgtat agtgggaaaa aagagtccac ctttgtaaag gcagaccctg agttagttga
    12721 aaaactttta agaaacacta gttttcttga gcgtttacaa aaaaagccta tcaattttca
    12781 gatagactca gaagaattta agcgtcttag ctatgaagcc attcatgata cttctcaagt
    12841 aactcaatag tagttattac agaagtcaaa ccactgacct tccccagttg caatccgtct
    12901 gtatggtcaa tctgtttagt agcttcatta gctttagcag agatagcttg catatcttca
    12961 gctgttaaag attctcgaaa atctttaaag gatttcataa aaactcctcc tttctattgg
    13021 aattttgact aaaacggtga gaggtcctag tcgagattat tatagcaatt taggaggata
    13081 ttacatcggt cttgaggctg atttttggag gcaatattgg aagataaaat catagaactt
    13141 gctgattact tcatcagcga atctacaacg tacagagaag caaaaatagc gtgtgagaag
    13201 ctattgaaac aagtcagcca cgagattgaa ctcagggcga tggaaagtag gacagtatga
    13261 aagaagcagt aaaggaattt ctaaaattca ggagccgatt tacaaaaata gaatggtttg
    13321 aaatcaacca agctgtcgaa gctcgtttaa atcaaaaagc cgaccagttg aaactggacg
    13381 acgtagattt agaaatcatt tctagcagac tagaaaaagt tatctagaaa cgatttgaat
    13441 gaacattgga tggatacgat agtcagcgcc acgatagtga atgtagatat aatcctgatg
    13501 gtacatcgag tttgcttcag gtttagaaat tggtgagtag agttctgcat tttcttccca
    13561 ccaaatgtaa ggactagcca tatttggtcc cattacacaa tcgtcgtcgg ctgataggtt
    13621 cacccaattt ccgcaaagac atgcgtgaat ttcagtcata atattacctc ctttctggtt
    13681 tcattatagc agaaaaggag atagcaaaaa agcacctgac ggaaatcagg cgcatactta
    13741 aatattcaac atgattataa cacgaaagga gcaaaaatgg aagcagttga aattgtaaga
    13801 attaaagatg tgattattga aaaagtctct gctaatgatg aagagttaaa acgtatcttt
    13861 ggatgttcaa aacgacaagc aggagagcga agaagagaaa tgcaaaaact ccctagtcag
    13921 caaaaacatc ttttggatag tggacaactt gtaacgatta aaggtttcta tgaatacttg
    13981 caatatcgtg gaactaaagc ttggaaaaaa gaaatggaaa caagcaagaa aatgaggtca
    14041 gcaggatgaa cctactatca agaatcaaaa actatttttc ggaagaggtc aaagaaacta
    14101 atctcgactg gaaagaggtc gctttagacc tcaatcaatc actaattgaa acacaggaaa
    14161 aacttcaaga agcgaatcaa gaaatcgcag acttgaagaa aatcgtagca atctataaag
    14221 aaaaggagaa agaaaaacga tggaatatat ttacctggta acaatcgtag gaattggact
    14281 atggtcgcta gtaaataaac tagatgacca cgctgaaatg aaacaaaaag agcgccagct
    14341 gatggcaaac aatgtcgcac ggatgaatct gagaaattca gataagcaat ttacttatga
    14401 tgtagaaccg cctgaagggt tgaaataagg aggagaaaca tgactcaagc tgaacgaatt
    14461 agggaatatt atagagagca ccctgctgcc tcatatgatg aagtggctga ggtcgttggt
    14521 acaacaaata gtaatgtgag agcgaacctg gccaaagaca tcaaggcagg cagatgcgtt
    14581 cgcttggaag ataagtcata cgattactcg ccttactata accatacaca ggcactcact
    14641 gagttggttg actggaagaa tgacaacaga cgtgagtggg tggatatgct gacaagagca
    14701 gcagagaaag aaacggatag caacgttatg cgtttgttaa tcaaagaagc aaataaattg
    14761 atgaaagagg tgactaagta gatggtacga aataaaatag gtgatttaac taacacgctc
    14821 ttcgctcaat tagagactct ggatgatagg gatcttacag cagatgaatt aaaagtagaa
    14881 ttacaccgct cgaaacaaat ggtcgcaatc tcaggtcaaa tcttacaagc aggtcaattg
    14941 gcgctagatg ctgaaaaatt caaagacaag gtaggtgaag tcaatgcccc gatcgctttg
    15001 ctggaaggat gagtacacgg agtacatgca tgaaatatgc cctggtcgtt taactcctga
    15061 agtaaccagg ttgctgaatg aaaaatttgg tacgaattat aacaagagtc aaatcggtgg
    15121 cgtacgcaaa cgtctagggt tagcagttgg aaaagtctat caaggtcgat tgctgacaaa
    15181 ggagcaacat gattatcttg tattgatcca aaaaaataag atttctcgta atgtcgcaaa
    15241 tgaaatgaac caaaaatttg gcttatcgct aactgagaaa cagattaaga gttatcggag
    15301 aaataataat ctacatagtg gtttgacagg aagattcgag aaaggtcaga ctcctcacaa
    15361 taaggggaag aagtacccca atatgccaaa aaacggcggg cagttcaaaa aaggtaatcg
    15421 acctccgaat tatgtacctg tcggtactat caactacaca acaaacggtt atccaaaaga
    15481 aaagattgga gaacctaatc aatgggtttt gaaacaccgc aaggtttggg aggaccatca
    15541 cgggctgata ccaaaagggt actcaatcgt ttttctggac ggtgataaaa caaactatga
    15601 tatttcaaat ctggcatgtt tatctaagaa cgaaattgct agaatgaatc aaaatcattt
    15661 attcacgtcc aacgctgatt tgactaaatc aggtattgga ctaacaaaac ttacaaataa
    15721 aatcagagag gtagaaaaaa atggctagtt tatacgaact aacaggtcag ttcctgacaa
    15781 tttaccaatt ggatatcgat gacgaaacaa aagcagacac gcttgaggcc atcgattggc
    15841 aagaacaatt tgaacagaaa gcagaaggat atgcccatgt tatcaagaat ctagaagccg
    15901 acgtggcaat gtacaaggct gaggaagaga gcttcaaagc caagaaacag gtggcacaga
    15961 aaaagctgga ttatgtcaag gataacatta tggcagctat gaatgtcacg gggcaaaccg
    16021 aagttaagag tggtgccctg attataaaaa ttgctaagaa tccagaatca gtcaaggtca
    16081 acgaagacga ccttccgaaa aaatatttta caaaaaaagt gacgcttgcg ccggacaaaa
    16141 aaacactcaa agagttgctt aaatctggca agaaagtcaa aggtgcggag cttgtccgga
    16201 cagaaaagtt ggtgattaag taatggaatt gatgaataaa acacgagtaa cagattcact
    16261 agcagttgtg attggaccag aatcgattga agtacttgtt actgaaggtt ttctatttga
    16321 tgttgcgatt cgttttgtaa aagtagacga aacaaatctt gatcaaggaa atgaaaagcc
    16381 agtattcact ccggaataca agctggtcac agttgctaaa tacaaggaaa aacctatctt
    16441 tgaatcggag gaagatattc gaaaatttga gaagcaagca aaagaagtta aatcgctatt
    16501 tgcctttgca aaggtaaata aacaaaattg gtttaacact gccctttatc caggagtgct
    16561 gactgagaaa gttggtgttt gatgaaaatt ttagctattg atccaagtag taataaaatt
    16621 gaaaccagca caacaggagt tgtcttgttg gataatgcaa gattagttga tagctgggtt
    16681 gtctcttatg gtatgagagg tttcgctgat tggtttcacg aaatcggaac aaatcttgaa
    16741 ttcgatgtag ttattgttga agaatttaag gcgagggata acgacaagtc gaaagataat
    16801 agcgtggcag aaaccatcgc ctatatccaa ctttgctatc caggtgccat tcttcaattc
    16861 aatgcaggtt acaagtcgga tattccaaac gatcttttga aaatcttaga cctttggaaa
    16921 tttgaaaaaa gtcatcatca agatattcga gcagcagcaa gacttggatt attttgggca
    16981 atgagaaatg atattgaaga agtggttcat gatatcggaa aggtggtgag tgagtatcac
    17041 aataacgcta agaaagtggc aagctgaagc gattaaaaga agtgaacatt tatctaatgg
    17101 aatcttttta gaggctcttg ggggcagagg caaaactatc tgtgcacttg ctattgcaaa
    17161 acataaaaaa gctaaaaaaa tcatcatcac aaacaatcga ctagctattc tgaatggttg
    17221 gatagatgca gtcaagttta tgaattttga taaaggtgtt gagattatca ttcagacaga
    17281 tagatatctt caaaatcaag tcaaaaaggg gcataaatta gattgtgatg tgctgatagt
    17341 agacgaatgg cagaatatgt cttctgacaa acaagtggcc ttatatcgca aaataaagcg
    17401 aaaatacacg ataggtcttt cagcgacacc aattcggaaa aaaggacaaa atttctatcc
    17461 gcttgaaaaa acggtatttg gttgggcaac cccaaataat aaatttgact ggcaaaagac
    17521 tcatggaaaa atggtctatg atccatttag ctattcaaaa gagaagtggg aagattttca
    17581 aaattatgaa agttatatct cgagcttgcc taatttcttc cgctgggaag agattgaagg
    17641 aattgagaat gcagttgaga ataacggttt tgagattaag ttttaccaaa agagagtcgc
    17701 ctctggcaat ccagaaaaac ttgcagaatt tagaaaacta aatcttgtaa cagtggacgg
    17761 caaaactgca atggccaagc aatcgtttgg aagaaagacc tttgaacgct accttaatca
    17821 aacaggcgta gcagtcgatt ttccaaaatt aaagccagta aatgcggata cgccattgat
    17881 gttacaactt gacggtttaa tcgaacgagc accacacgat atgttgattg tcagtaaatc
    17941 taagcagatt gtcaacgtca ttagcgagcg ccatcctgaa attggaatct ggacgggcga
    18001 tattcaagaa ggactttata agaaattcgt ggttgctact agtcaagtgt taggtgtcgg
    18061 agtagacggc ttgcaacaca aataccaaac tattgtcgta ttggatccag tagaagaagg
    18121 ttctggagaa tatgatgatt atcgacaatt gctctggcgc ataacaggaa gtcgtcagca
    18181 gcatgatgta aatgtaattg aattttatta taaagaaagt taaaaaaaga ggaaaacaaa
    18241 atgaataaaa caactgaaat gatcgtattt cgtagccgta aaactggaga atttcttaat
    18301 tcttacaagg acagaagttc tttagcattt gcagctgact tttgcagctt ggaatattgt
    18361 ttgaagcttc ctcgtaaaaa atacgaagac aacaaaaaga cttacaaggc tcttgctgca
    18421 gcttttgact gtgaaattgt cgcagttgaa gcggaataca aattgaccta tccgaatgga
    18481 tcagaagttg aacctatcaa gcgtgaccgt tcatcaattg aggacatgat taaggatatt
    18541 attggagggg ttctctaatg gcatttacac ttccagcaaa taaaccacaa gttcctaaag
    18601 ataccccacg aaattttttc atctacggcg aaaccatgag cggaaagtct tatcttgcaa
    18661 atgaattccc aaatccaatc gttttgaaca cagacgggaa tgcagaagct aacactgttc
    18721 caagcattca gctgatcaat gaaaaagatg acaagggacg aattaccaat tcagtaatta
    18781 agcagcttgg agatatcttg cttgctctcc agacacagaa gcactcttat gaaacagtcg
    18841 ttattgatgt aattgacgat gttattgaaa tgattaagat tgcagtttgt gatgaattaa
    18901 ccccagttgg taaacctcgc ttgaaatcct tgtcggaaat tccatacggc aaaggatacg
    18961 acttctttaa ccaagctatc acagaattag tcattgacct caaagcattg ccaatgaatg
    19021 ttatttacat cagccgtcag gtatctgaat atgatgacaa tggcaatgcc accaaagaca
    19081 agccaagctt gaaagataag tatgtcaatc ttatcaatgg aaactctgat ttgatgatcc
    19141 acactgaaaa actcggcaac aactacaacc gtgaggttga ccgcaagcgt aagacctatt
    19201 atgcggacca ggttgatgac aaggccatct tgaaaatctt ggcaactatc cgtggggctg
    19261 ttgagcctgc aaagggcaag ctagccccta aaaaagaagc agctaagaca actaaaccag
    19321 ctaagaccga aaaaacaaaa gaggcaccta agaaagaagt tgactctgat gatgaactat
    19381 tttaagaaat aaaggagaat acacatgagc ttactagata tcgcaaaatc aatcaaaaaa
    19441 gagggctttg acccacgcaa agacagcgcc aacggtcctg caccaatccc agctggtact
    19501 tatccagtag tcctgaagaa agcaaccttc aacgtatcgg acaaaggctg ggaaagcctt
    19561 ggttatcaat ttgaaatccg tggcggtgat tacagtggac gctctgaatt tgcaacattt
    19621 ggcacactga ctgaatggaa cggtaagaac cttgactggg cagttgaacg cactatgaaa
    19681 ttctttatca aagccttggt ccttgctggc gacagtatgc aaggaaatga agaagacggt
    19741 aaagccttgg aagaggctct acaacgtaag gcagttggct cttactacaa ccttgttatc
    19801 tctgtgacta aggggaaaga tggccgtgag ttccgaaact atgaccttga agaagaagca
    19861 caaccgctga ctgaagctga tatcgatgaa gatgacctcc ctttctaaaa aatagcaagt
    19921 tttgggtcat tgatgaaact gatgaaagat taggaccatt caatacattt gaagaggctt
    19981 atcaatcgtt gttattttat ttaaaaatga ctgaagatga atatcagtca aactatacgg
    20041 cccaggaact tgtttatatt tacaaagagg agaaaaaacc atgccgtcga tgaaagaata
    20101 cgcattacag taccaaaagt tagggttctc agtcattcca atcaatccta aaaacaagat
    20161 gcctttaatc gaatttgctg ataaaccagc catgactcca tctgagattg aaaacttttg
    20221 ggacggctac cctaatgcaa acattgccct aaagactacc aacttctttg tcattgatat
    20281 tgacaaacac ggcaaatcga acggttttga atcgctaaaa aaatggaaac atctaaattt
    20341 aatcgaaccg acactgcaag ctaagacggc tagtggcggt aaacatctat tctacttcaa
    20401 acgagaagat gagccgatca ctcagatgat tggattcttg cctggtgttg atattaaggc
    20461 tcacgaaaat aattatgtgt tagtcgcacc ctctgccaca gataaagggc agtatgagtg
    20521 ggatctggaa aagtctaagg aaggtggcac gatggtcact ccttcaaaat atttaatcca
    20581 gtctataaaa aaacagtatg gcgaaactca cggttataag tatgatggta aggacggtct
    20641 tagggattta gttagacgtt cacatactag agaccgaaca cagactacag atctctttga
    20701 aaccatcgcc cttggttttg gtgatgaagg tggacgaaat gacaaactag caaaattcgt
    20761 aggtggtctc ttatatcgtg cggtcgacga tggtgtagtt gttcaacttg caagattagc
    20821 aaatgcaaat agtccaaccc ctttgcctga aaaggaaatg atgcgtacta ttgaaagtat
    20881 gattaaaaaa gataggaggt gattgtgatt ggtaatgtag taagtattga ctcacaacct
    20941 aagatgataa cgactgccaa gggagacatc aaggccaaca gtccaagtaa tgtgttgatg
    21001 tctttcaaag ctgatgatca gttgagtatt tacctaaagc acaacgattt ttcccaagag
    21061 catgaactcc ttaaagatat caagatcggc aacactcttt ttaaaaaagg tgagctccct
    21121 tctaactttg attcagtcgt aaaagtttac tttgaaagtg tgttaggtgt tgctttctct
    21181 agccaggcga tgctggacgg catggaaact tttttctcag aacgttctta caatccagtc
    21241 attgagtata tggaaaaggc tgctgaaaaa tgggatggtc gtaaacgaat tgaccgaatg
    21301 cttcaggttt acctgggggc tgaagatatc cctttagttt ctaaaatcgc tcaaatgtgg
    21361 ctagttggtg cagttgctaa agtttatgat ccatacgtta agtttgacta tgttctggat
    21421 ctagtcggtg gacaaggagt tgggaaaaca tccctccttc aaaaattggg tggcgaatgg
    21481 tatacggatg ccgtaacaga tttctctaat aaagataatt acgacattat gttaaagagt
    21541 ctaatcgtca acgacgacga aatggtggcc agtaatcgga tgagctttgc agaaactaag
    21601 gcctttattt ctaaaactag cctacgttat cgtaaaccat acatgaaacg cacagaagag
    21661 tttgccaaaa acttcatttt agctagaact actaaccaaa cagaatacct caaggacaaa
    21721 accggtgaac gtcgttttct accagttatg gcagatagta aacggcaaaa aaaacatcca
    21781 atggaaatcg agccagagac aattgaacaa atctggggcg aagccgttac aatctatcgt
    21841 gctggtgctg atttgatgtt tgatgaaaat acagaggatg aactgaatat ctaccgtgaa
    21901 cagttcatgt atcgtgatga agttgaatta caagtgcttg aatatcttga tatgcccgtc
    21961 cctgaaaatt ggcaaaactg gtctattcag caacaacatc aatacacaag taaatatttc
    22021 gataatagta gcgactttga tcctggaagc aaaaaactag ataaggtctc aactcgtgaa
    22081 atgatgtaca acttatttat gagaaattcg aatgacagga agctgtcaac gaagattaac
    22141 atgatcatgg ataatcatcc tgattggaaa aaaagtgttt tccgggcagg aggtaaaagt
    22201 acaaaagggt tcgtaagagt gaaagattcg gaaaaaacta atcggtagca attaaaaaat
    22261 tatcggtagt catcggtagc agttgagggg gagatcggta gcattctacc gataaaatag
    22321 gacatcggta gcacatcggt agcagtctaa ccccttgata ttactgactt ttatttaata
    22381 tttatatata atgctactct tctacctata tttttaaaaa aagtatataa aataatagta
    22441 ataataaaga aagcctatag aatagggatt cttgaaaaaa actttttact ttttagaatt
    22501 tatcggtagc acggtagcag tttagaaaaa agaggtaaaa atgtcataca cagtaacatt
    22561 attttttgac aacatggtag acgaaactca cttttttaag aaagagagtg atgctgccaa
    22621 atgcaaggct cagttagaaa gcaagtatcg agggaatcga atgtataaag ttaagcagga
    22681 gaaattggaa gaatgaataa gcaggaactg attaaacgta tcgaggattt gccttataca
    22741 gaggggccta tcgcagatac aatcgaaatt aatagaaatt ggatattgaa atcaattgaa
    22801 cagctagccg aatccgaaat aggtcacgca gatgaagctc cacgctacgt aaagaacata
    22861 ctagcacgat tgcgagaatt gccattgcat gatagagagt tttggttaaa ggctatcatg
    22921 agcgaatttg aacaggattt tagccatgca aaatggcgag agggctacga gcaaggtaaa
    22981 attgagggta tggttgaacg tgaaaaagtc atagttccgc agtgtgtggc ggaatatata
    23041 gaatttaaaa agaaaaacaa ttttcatgtt tacggtgcaa tgagagtaat tgaagatcat
    23101 tatgataaga aagttcctga ttggttttac gaaaataaca tcgaaaaatt ctgtcttgct
    23161 tggcttgacg gctacgaggt tgaaaaagag aagcggtatt ttgttaagat taaagggaat
    23221 attaaagaaa atatgttggt ttatggagaa cttttgaaaa ggtatttctt tacaaaaagc
    23281 tttagtttag acgatgttat atattcccac acccgtaaag aactagaaaa tgcaaaaatc
    23341 ggctgggtgt ttgattgtga agggtttgag attgaggagg tggagtgatg agccttacgc
    23401 taaatagcac aattggagac ttagttttgg caatcggaga aattatcgtt ggttctgatg
    23461 gtaaaaccac tacagcgata ctggagatac ctgatcaaag cttttactta gagattgagc
    23521 ttaaattgaa ggaggaggtc ataaattgaa acgattcata gctatctgga ttctgctatc
    23581 tgctggattg aatatctggc agagtatcta cattaaaaag ttagaagaaa agcgccctat
    23641 tgtcgtctat aaagctgata acgcaggcgc tgagatattc ggtaaagtcg tcgagaaagg
    23701 acggcatggc aagctataca cgcttaccat tcgtgactac ggggtgttcg tggttacgaa
    23761 ggacgtgtat gagaaagtga aagtagggga tgaggtgtta ctctaatgga tgatatttta
    23821 caagctttag caaaaatgct aaatatgact gttgatgaag taagttcttt gcttacaaca
    23881 tttaaaggga atgcaccaca gatttatgaa atgttcgtta aagaaaagat gttttatgat
    23941 ctcttcagtc tttttcaaat catgtcaatt gtaatattta gtatttctgc agtagtttta
    24001 gcagttttaa ctctcatata ttttacatac gatggtggtt ttgtttattc ctatgatata
    24061 cgtacaggaa aaaccgagga agaaattaaa ttagaacgca ttgaacggaa aagaaaggac
    24121 ttaaaaatac cactaaaaat tagttgcatt tcatcaagcg caagtttgat aacattagtt
    24181 attgcaattg ttttaaaagc aactcttgca cctaattata tattcatcgt gaatgagatt
    24241 ttaccaaaat taacgaagag ataggagtta tcatgaacgc actagaaaaa gtcgaacaat
    24301 ggtttatcga ccgtgaaatc aaagaccgaa aaggtcgctg gattgatggc tcgtttgtca
    24361 aagaggagga tttggcatga taccgaaatt tagagtgtgg gtaaaaatag gaaaacgtat
    24421 ggttttttca gatgacattc ttgctattga ctacgaaaac aaagaaatag tgacacaaca
    24481 agtttatttt gagaatggtt taccagacga tagagatatc tattgttatg attttgacga
    24541 aatcgaactc atgcaatcaa caggactcaa agacaagaac ggcaaggaaa tctttgaagg
    24601 cgatattgta cgaactacta gatttttggg tagagctgac gaaattggcg gtttctatga
    24661 gtatgacaag gaatttatag ggattgttaa gcagcttgag ggttcttggg taattgatac
    24721 gggcagtgac gcagtatgtt tatggactga aattgaagaa aatgaaatca tcggcaacat
    24781 ctatgaaaat aaggagtttg gaggacgcaa atgagacctt gtaaatatcc atattcagga
    24841 agaagaaaaa aacaagaaac gccgtcgcca atattttctg cacgaccaat ttttgacgaa
    24901 gttccaattg tagaagaagt taaggttgag ttcggagttg aagctagtat ggggcgcata
    24961 tatccagaaa cgttaataca tttagatatt tctggatacg gaaatagagt gcattcagta
    25021 catcgcttcc ccggtatttt actgagtgtt ggtgagtcaa tccaactaaa gatgcttttc
    25081 tataaaagac ttagaaattt tactacagat cgtttcttga cgtttagaga atctgattgg
    25141 aagttcttta tccgggacct ggtcaacgaa tttaagcatt aaaaaaagcc aagacactct
    25201 ctgcctcagc taatagttct cgcaaagact attatatcac aaaggagaca gagagtgaac
    25261 aaggctaaag agctcttgaa agagttgcag gatctggaca tggacatcca aagccgtata
    25321 gacgaaatta acgagcttga ggcaggtttg ctctcaagcc ctaaatggtc cgaggttaaa
    25381 gtccaaggtg gacagactag aaaagttgat gatgtctata ctcagttggt agtgatgaaa
    25441 gaggctatag agcaggatac taaagaggtc attaacagaa aacttgaatt aggtagaatg
    25501 atcaataggc ttaaaaatcc aaagtacagg gcagtattaa gaatgactta catcaacaaa
    25561 ggcaccgctg atagcgtttg ttatgatttg aatatgagtc gtacaaccta ctacaggtta
    25621 aaaaatgagg cggtcttagc tttggaagaa gttatctaac ctcatagtga gcttatggga
    25681 ctttttggaa cagcacggtt ctaaaaatct gttagaatgg tagtatcaag aattgaaaag
    25741 agaggtctca gaattggtag atggttacct gtaatgtcag ggggctgtaa tggccttgga
    25801 ggttcaagtc ctcccctctc ctttgagtgt ttgtgtccca gaatgagtta aatcttctgg
    25861 gtggggattc acatatcact cattaactcc tatcactcat taacttaaaa atggttgcgg
    25921 aagcgactgg acctcgcatg attgcgtagc taattatatt ccggataagt tataagctag
    25981 agggtttgat tccctcagag gttttaaaga ctacaaaaaa taaaaaagaa gtcaaaattt
    26041 aatacgcacg caaggtagta gtcgccttgc aagaaggtcg cacatcgtgt ggcttttttt
    26101 gattattcga agggtggtga tggaaaattg agtggattga gaataaaaca aaagagattt
    26161 gcagatgagt acatcatctc aggtaatgcg acggaagcct ataagaaagc aggttatcgt
    26221 gtttctagtg atagagtggc aggcgttgaa ggacataagt tactaaagaa tcctaagatt
    26281 aaaagctata tagatgaacg actgaaacag cttgattctg aaaagattgc ggatcagcaa
    26341 gaggtcttag gttatctaac ttcagtcatg cgaggagaga cgcaagaaca gaccttgata
    26401 agcattggag aactagggca gacgattacg gatatagatg taggagctaa agatagaatc
    26461 aaggcggctg aacttcttgg taaacggcat aggctttgga cggataaggt agaggcggat
    26521 gtttctggaa cggtggtgtt tgcaaatgag tcagacatat cagattaaac aaaacgatat
    26581 tgtcgttgac ttacctaaga cagtaggagc tggatacgga cagttctggc gctcaagaag
    26641 tctttatcgt gtagtcaaag ggtcccgtgg ttcgaagaag tccaagacaa ccgctttgaa
    26701 ttatgttatc cgtcttttga agtatccctg ggccaacttg cttgttattc gtagatactc
    26761 gaataccaac aagcaatcaa cttatacgga ttttaaatgg gcgtgtaatg tgttgggtgt
    26821 gactcatttg tttaaattta acgagtcttt gcctgaaata accataaaag cgactggtca
    26881 aaaaatccta ttccgtggtt tggatgatga actcaaaatt acatctatta cagtcgatat
    26941 cggtagtctg tgttgggcat ggttcgagga agcatatcaa attgagactg aagacaagtt
    27001 cagcacggtt gttgagtcta tccgtggtag cttagatgta cctgatttct ttaaacaaat
    27061 cacagtcaca tttaacccgt ggaatgagag gcattggctc aagcgtgtat tcttcgatga
    27121 agagacgaga cgggctgaca cattcgctac tacaaccact tataaatgca atgagtggct
    27181 tgatgaagtc gatatcaaac gctatgagga tttgtatcat acgaacccca gacgtgctag
    27241 aatcgtttgt gatggcgaat ggggagttgc tgaaggttta atctacgaaa acgtgactgt
    27301 caaggatttc aataaagatg aattactaca agattcagct aataaattat gtatcggtct
    27361 tgactttggt tttactcatg atccaactgc tttgtgttgt tcgttgataa atgacacgac
    27421 gaaagagatt tatgtctttg atgaggcgta taaagtcgga ttgataacca aagaagttgc
    27481 gaagatgata aaagacaaag gttatcatcg ctcacaaatc attgctgata gcgcagagtc
    27541 acggctgatt gaagagctca ggtcagaaca tggcatatct agaataaaag agagtcggaa
    27601 aggtaaggat agtattatgg caggcgtatc caaattgcaa ggatacgcta tttatgtgca
    27661 tccagattgt aaaaacatca tggatgaatt ttatagttac tgctaccagc gagataaaga
    27721 aggcaactgg ttgaataaac cagaggataa aaacaaccac ttgatggacg ctttgcgtta
    27781 cagccttcaa tgtatcgaag gtggaaaagc aaccgtccgc agacgttctg attatggtct
    27841 atagagagga aagacatgta ccaatattta acctatccac gggatggata tgatgagggt
    27901 tctttgaaga aagacctgat ttacaaattg ataacgatac ataacactga aagctcacgc
    27961 ttgaagaatt taaaaagcta ctacatgggt gatcatgcta ttttaaatca caagagacgc
    28021 aacgtgaacg cacccaatta caagacggta gctaatcatg ccaaggatat cgcagacacg
    28081 gctacgggct attttatggg caatcctatc aagtataaca atactgctga cggtgatatt
    28141 gatgaactac ttacagcctt tgatggtgct gagattgacc aagtggatgc gcagaacgca
    28201 ctaaatatgg ctatctacgg ccgtgcttac gagtacatct atgctaaaga gggtatgact
    28261 gagttggatt caactagtat tgatccggag aatactttca tggtctacga tgatagtatt
    28321 gagcggaagc ctttgtttgc ggtctattac tatgaagtaa aagacgatac gaaagacact
    28381 accaagcacc aggctgaggt ctttaccgaa aatctgcact atcacatggt gctgagaagt
    28441 acagattcag gaacaactca gagcgaggag gcaacacctc acaaccttgg tcaaatccca
    28501 attatcgagt atcgcaataa tcactttgcg attggcgact acgagcaaca aattagcttg
    28561 atagacgctt ataattcctt gatggggaat cgtgtcaatg ataaggaaca ggctgtagag
    28621 tctatccttg tcttgtatgg cacgcagtta gcagacactc cagaagacgc taaggtagca
    28681 atgaagattc tttctgaaga aggtcttttg gaattgccgg gcgatagtgc aagggctgag
    28741 ttcttgaaga atacgctgga cgaaagtgct actgaaatct tgcgtacagc tcttaaagag
    28801 gacatctaca catttagcca tgtgcctaat ttgactgatg agaatttcgc agggaataca
    28861 tcaggcgtag ccatggaatt taagctgatg ggccttgaga tgattactaa gaccaaggaa
    28921 gcgaactata agcgaggatt gcgtcagcgt attgcgattt ttgctcatta cttaggcatg
    28981 aagcagattg ctttagagtc tcattcaatc gttccacaat tcagtcgtgg tttgcctaag
    29041 aacttattag aaatctctca gattgtgaac aatttggaag gcaaagtgac caatagacag
    29101 cttatttctc tcttgccgtt tgtggaagac cctgacgctg agctggaagc cttggaagaa
    29161 gagaaaaaga agaacatgga agacatgccg atgttcaaca aagacaacac gaaacccgaa
    29221 gacgaggtag aggatgaaga atcaggagta ttgggcgaag aggaaagcca atctgattta
    29281 ccagcagatg gacaaggccg aaaagcaggc agaccagttc gataaggtct atcaggaagc
    29341 taagacttac ttggataagg aaatcaataa gattttcgat aaattccaac gtgattatgg
    29401 tctaagtcag gtagaagcta gacaagtctt gaagaacatg aaagacaaga aaaatctgaa
    29461 tgaacttcgt aaagtacttg aagcgagacc gaatgacccg aacatccaaa gattactagc
    29521 tgacttagac agcccagctt attctttccg catgaagcgc ctagagcgtt tgagcgacga
    29581 tttagatcgt atgcgtgaat ctatctatca ttcggagaag acaggctcag atgcctttta
    29641 tagcgacctg atgaaggata gttactacaa ggctaccttt gacctacaac agcagacagg
    29701 actagcatat ggcttttctg ggcttcctga gaacgagatt aaacatctac agtcttttag
    29761 ttgggtagga gatggaagta cgtactcaac agacatctgg aagaatacag gaaaacttac
    29821 ttccagcata aaagatgaac tcctcattag cctcatgaca ggcagagata cacgagaaac
    29881 tgcacaagca attgctgaga ggttcaatgt aggtcagaac gatgcaaggc gtttggttcg
    29941 aacagaatcc gccttttttc ataaccagat ggagctactc agctatgaag aagcagacat
    30001 agaaaagtat atctttgtgg ccgtcttaga caagcgtaca tcacgcattt gtcaggagca
    30061 tgacaatcag gtctatgata gggataaggc tgtccctggt gtcaattgtc cgcctatgca
    30121 cccttggtgt aggtctacta ctgtcggata cgatgaggac gcagactaca gcaagttgaa
    30181 gcgcagagca aggaatccag agacaggtaa agttgagtac gtgcctgccg atatgactta
    30241 taaagagtgg tatagcaagt atgtggatgg taatagagag tctattaaac gtaaagcgtt
    30301 tgataaaact attaaagatg gtataatagt aagtgtatca gggactacaa ttggacacac
    30361 tccgcctggc aaaataggtt tgcctaatag tgtagttcag cataatgcta caaacggaga
    30421 tgtccttggt agaacttact atgatgctag aggttttaaa acgaaagatg ttcattttac
    30481 aaaccataaa caaccggcac gtcatcctta tggaaaaatc ggagaacatg ctcatgattt
    30541 tgtatttgat gatgaaggta agttcgttag taggagtact agggaattaa cagacgatga
    30601 aagaaaggag aatcaagata tattatggcg atattagatg atttacaagc gttatatgat
    30661 aatggatggg acgcttcttt taattataat ggtcaagtat gtggcatttt ccctaattct
    30721 atttatgatg ttgttgttat tattgcggac gacgaatata gagcatcttc ttttgacgat
    30781 ttgatttctt tacagattga agggaaaact ttaccggaaa tcatgaacga agttgaagta
    30841 caatatggct aaagcaccta gagagatcta agtgcttttt tagtacccag aaaggagact
    30901 atccgtacga ttttcttgat tgtgaatttg aagtaaaaag aatttcagtg atagcttgcg
    30961 atactatcct tatagaagcc taaaagaaag gaacagaaaa atggaagaat ggaaagaaag
    31021 atttaaaaaa gaatactacg aattgaaaga acgattccag aagttagata tgatgattgg
    31081 gaaatacgaa aaagggcaac tagagtttga atctaaatgt ccgattgatt cgttaaaagg
    31141 tcagcgttca accatgtgga attatttaag aattctagaa caacgtgcaa aaattgaaga
    31201 aattaaacta taaaaattaa ccgcatcgaa atcgatgcgg ttttcctatg ccctaaccgt
    31261 atggaatccc gtacggtttt tatattgtcc aaactgtacc gatgacaata aaagctgtgc
    31321 tgttccgtcg ccggacgtaa aacgagatta tcgagtggcg acgtaatcgc tggaggacaa
    31381 ttatgtcaga agaaatcaat gcaactgtat ctactgaatc aactgagact gtcgacactc
    31441 aaggaaatgt tgattcagtg caggaagaaa agcacgaacg aactttcact cgtgctgaaa
    31501 tcggtaagat gctatctgcc gaacgctcta aatgggaagc tgagcaagaa gccaaggaaa
    31561 acgaagctaa gaaacttgcc aagatgaacg ctgacgagaa acaaaaatat cagttggatc
    31621 agcgtgagca agaactagct gaccgtgaga aggctattgc tcgcaaggaa ttgaccgcag
    31681 aagctaaagc aatgctaagt gaacgtgact tacctgttga gttagtaaat gtagttgatt
    31741 tgacaagcgc agagacggta tcgcagtctg tcgctgtatt gcagaaatca tgggagcaag
    31801 ccgtgcaaaa aggcgttcaa gaaaaactaa aaggcggagc tccaatgaaa caagcgccag
    31861 tcgatagtga cggtatcaca aaagaagaat ttgctcgtat gggttatcag agtcgaaatg
    31921 agctctatca aaagaaccca gagctttata agaaattgaa aggataatag aaaatgacag
    31981 caggacaaac taaattagcc actatggtta atccagaagt aatggcggat atggtagccg
    32041 ctaaattacc taaattgatt aaatttacac cgctagcgta tgtagagaca aagcttgaag
    32101 gtcaaccagg tagcacttta acagtgccag catgggagta tgcaggagac gctactgaaa
    32161 ttgaagaagg ccaagcaatt acgccagacc aattgactac taaaaagact actatgacca
    32221 tcaaaaaagc aggtaaaggt tatgaaatta ccgatgagtc tcttttgtca ggtcttggtg
    32281 acccactagg tcaagcgact taccagcttg gtttagctat tgccaacaag atcgataatg
    32341 atttggtagc ggtagctaaa actgcaacac aacatattac agaaactcca acaactcttg
    32401 aggcaatcga taaagctcta gatatctttg aggacgaaga agatgcacag tatgttgcta
    32461 tcatcaaccc taaagatgct actaagctaa aaactgcagt agcaaaagaa tggattaaag
    32521 gttcagagct tggagcaaat atggttgttt ctggaacctt cggtgaagtt gatggtgtgc
    32581 aaatcgtgcg ctctaaaaaa gttgatgaag gtaaaggctt ccttgttaaa gtgtcaccaa
    32641 gtcaaactca gacagacgac gctaacaaat atggagcttt tgttatcttg cttaaacgtg
    32701 atgtggctat cgaaacagac cgcgatatct tgaagaagac taccgtaatc acaggtgatg
    32761 aacactacgg cgtttacctt tacgacccta cacgagttgt aaaattcggt ggcgcgtaag
    32821 aggtgacgat atgagtttat tgctacgacg tcattatatt caagaagagc aggttaacca
    32881 gtattctgat ttagagaata aaactctaga agagttgaag gatctagcga aagaagcagg
    32941 tgtagcaggc gcttataagt tgacaaaagc cgaaattgta gaagttttgg aggaactaaa
    33001 aagtgaaatt taaaatcaaa caagatttct atgattggga atcaaatgtg aaacgactgg
    33061 caggagagga acttgagatt actgaggagc gctatgctga gctggctgac aatattgcca
    33121 gcaacggtgt cactatctca gacgttcttg agaaaatcct ccctgaacct gagttcttag
    33181 aagaggattg atatgtctat agagttgctg aagaaattaa caggcgaaga agatactcag
    33241 cttctcatgt tgctccaaac gagggctaca aatcttatct tgtcagagac taatcgcaca
    33301 tctttgacac ctgctttaag tcttttaata cctgaggttg ctatcgaact ccacaaccgc
    33361 tcaggagcgg aaggagagca ttctagaacc gagggtggta tagcagtagt ctacggagaa
    33421 aacggcctgt ctacggatct tctacagcga atacgcatgc acaggctagc aagggtggca
    33481 ggtcatgttt ttgaagcaga gtagactgaa accttatcca atgcgacggt ttgaaaagac
    33541 tgtcactgag gaaggtgtcg cgaaagaagg gtatgccaag gaagctgaga cagtccgcct
    33601 tgaattgtgg ccagctagta gcaagctaca atctgaattg tatggcgagc gtgtcaatga
    33661 tattttgaac gcaaatgcca acaagtcagc tactatcaaa gtaaaagatg gtgtgtgtat
    33721 cgatagtcag acggaagtga ctcatagggt tatttctaaa aaggtctaca cacatcatca
    33781 agttttggag ttagagcgtg tcagggctac taggggcaga taggcttata gctaaatgta
    33841 gacgattggc tagtaaaaaa actggcgagg atatcgtctt acgtgcggtg cacaatgcta
    33901 ctataaaggt tgtccaagca gatgcaagaa gactcgcacc agcgagagat ggagagctta
    33961 taactagtat caaaactagg gcaaaaatgg acggagataa ggctataggc gaagtttaca
    34021 ccaaccttaa atacgctcct tatgttgagt ttggaacggg accaatagga caagctagcc
    34081 attctggtat ttctccagag gtcagcgtga cttacaagtc tagtccgtgg tatgtacatg
    34141 aagaccaaat caatgtagga ccgtaccact ttcaaaaaat cggggagttc tacaagatgt
    34201 atggtcaacc tgcccagcct tatctttatc cagctttgag agacaatcaa gagcgtgtgt
    34261 ctaagaatat ttcgaattat gtccgtagaa agataagaga acaaataaaa tgattaatat
    34321 caagcctgtt atttataaag aattgcaaaa ggttgcagat aatgtgaccg atacttatcc
    34381 tagcgattgg gagactttcc cagtcgttat ttttttggaa gaacaaaaca agccgggtga
    34441 ttggtttgat gaccaggaac aaaaatcctc tatccgctac aaggtggata tctttgatga
    34501 tactagcact agtgagttag ctgttaaaat caatcagatt tttgagtctt taggtttgcg
    34561 aagaactgac tgccaagacg tgccagaccc gtctcatttg agacataagg tcatgcgttt
    34621 tgaaggtatc gtcgacttac actcagagct tgtttttcaa tttagaatgg agaattaaac
    34681 atgttagcaa atggaattac gctttcttat ggcgaaacaa aagatagcta tactaaactt
    34741 gttggattga aagaagtacc agagtttggt attgaactcg aaaaagtaga aaatactact
    34801 cttgaagata cggtgaagaa gtacgagttt ggtattgggg acataggaga acttgagtac
    34861 aagttctctt ataataattc aagcgcaact gctccttatc gtgtattgcg taaggcagca
    34921 gacgacaaga agaaactcta ctttgaacaa gcttatccag acggtactaa ggtcattttt
    34981 gaaggccaag tatctgttaa gcttggcggt ggcggtgtca atgccgttat cgatttcaca
    35041 cttaagattg ccttgcagtc taatcttaca tttactgatg gtattggagg ttaattaaat
    35101 ggcgttaaaa tacacaactt ggaaagttac tgacgaaaaa gagttgaagc tacgtttgac
    35161 atctcatcaa gctgcaactg tggaagaaaa aatcggcatg aacttgctga agattttcat
    35221 gcctgaagct ggcgaagagt tcactttacc gcctttgaaa gttatgttgt tgttagttca
    35281 cggagccttg cagcagtatg aacatgggta ttctcttgag gatgtctatg atttatacga
    35341 tgaatacgtg gacaatggcg gagaccaaac aaccttcatg acagaggtgt tgatgccact
    35401 ctttgaagta tcgggtttta ctccacgagg aagcaaggac aagaaaactt ccaagaagaa
    35461 aatgacagta gacaagtaat cttaacggta actcagatta ttgagaggct ttatcctatg
    35521 tttttggaca tcgagggcaa gcctcttgat ttttgggatt tgacggtact tgaaatcaga
    35581 gaaatgattg aaagctataa ccgtgtcaaa atccaagagc gtaaagaaaa gattattgac
    35641 tcatacagac tttcgcagat gatatccaac cacgtttctt tattgttatc caaagatgcc
    35701 aaggcctttg agttctggga atatgcgcct gagttgtttg tagaagaaca acaagcagta
    35761 gaacaggaac gacagaaaca agcacttttg ttgcataagg aacggatgcg tgaatttgca
    35821 gagagacata atcgaaaaag gaaggaggaa gtaaatggca actcttgatg aattgaaagt
    35881 catgattgac gctgagatag cgcctttcag gaagaagatg aaagaagtcg agaatcaggt
    35941 caaaggaaca tctgaccaag tgaaaaatgc tactgccaaa gttcgtgaac agtcgagctc
    36001 aatcggtagt gcgtttggca agctggctaa gttcgctggt tttgcaatcc ttggtaagaa
    36061 attacttgat gttgggatgt attcaacgca gacggctctt gaagtatcag cgtctatgaa
    36121 ccaaatcaag cgacagatgg gcgagagttc gcaatctttc ttaaaatggg ttaacgataa
    36181 tgccaacgct atgaatatgg gtgtgggtga ggctaccaac tacggtgcag tctactcaaa
    36241 cttattttct ggatttatca aagataccaa caagctaagc gcctataccg ctaagatgtt
    36301 gcagacatcg gcagttgttg ctgaaggttc agggcgcacg attacagacg ttatggagcg
    36361 gattcgctca ggtttactag ggaacaccga agcgattgag gacctaggaa tcaacgtcaa
    36421 cgtggctatg attgagtcca ctgaagcctt taagaagttc gcaaacggac agagctggca
    36481 acagttggat taccaaaccc agcaacaaat ccgccttatg gctattctgg aacaggctac
    36541 agccaagtat ggggatacct tgtctaattc tgtaaatggt cgtatcagcc tatttaagtc
    36601 gctgatgaag gacgcagcat tgaaccttgg taactctatg ttaccgatta tcaatgccat
    36661 tatgcctgtc ttgaactctt ttgctatggt cttaaagaac gttactgcta aactcgctga
    36721 gtttatcgct ttgatgttca acaagaaagc aacagtgaaa gatggtgttg gtggagcagt
    36781 tggagacatg ggtaacgcca tgaaggatgc tgcaggcgga gcaggagacc ttgctgacgc
    36841 agtagacgac gctggagatt cagcaggagg acttgctgac aatcttggag actccgccaa
    36901 aaacgctaag aaggccgcta aagagttgct aggtcttttg ggatttgatg agattaacat
    36961 cttgcaaaaa ccaaaagatg acgacgcagg cgggtctgga ggcggtggca aaggtggtaa
    37021 aggaaaggga ggcggtggcg gacctttcaa agacatcttg ccagaagtcg agttgaccga
    37081 catggacaac aaattcaaga gcatttttga tggtcttgga gataagctca aagggttgtt
    37141 tgacctcttc aagaaaggtt ttgatgcagc atttagacca gaaggtatag aacgcattaa
    37201 gactgcctta gaccaaatag ctaagacaat gggagaaatc gccactgacc caagggttgt
    37261 gaatgccttt aaccgaatgg ctgagaaaat tgcttatgct ttagggcaag tgacaggctc
    37321 aataacaact atcgggctag gtatcggtgt tttccttgcc gaaagtattg caaatggcct
    37381 tggaaggcaa aaagaacgca ttaccagggc gctagtcgct ttgtttgata atattggtaa
    37441 catttccgag gcagtaggaa acatcgctca ggacttttct agtactttct acgacgtcat
    37501 tacctcaact ggtgcggttc gtatcggtag cgctattgtg tcaactctgt tgagtttgac
    37561 atctaccatt gttgaagttg gtagtaaatt agcaggaagt ttgtttaaag gttttgaaaa
    37621 agtcgttgtg acaagcgctc ctaaaatttc atcagtcttc caaagtttat tagatactgt
    37681 tgcgcctgta tttgagagca ttgaaaggtc tgttaacaaa tttggcgatg gcttaagtcg
    37741 tgtttatgat gaacatgtag cccctgctat taactctatt gctaatgctt ttaacggact
    37801 gattgatatc atacaaatcc tctgggagaa ttcttggcaa ccttttgctg agtttttatc
    37861 aggagtattc ggtgttagta ttgaaggaat ttcagattta ttaggaggtg gccttttagc
    37921 cactttggga ctattggcgg atgctattaa gttagtggca gatggtttca ccgttttttc
    37981 tgactggtgt aaagaaaaca aagaacctat cttggctttg ataacaactt ggcaaacgat
    38041 taatttctta tcatgggctg aacaagccgg gggacttgca ggagcattca gcttgttagg
    38101 tagtaaggtc tctttgattg ttggagggat taagaatcta ggtcttgcta ttaaagcatt
    38161 gacatttgat aaattggtca gttttggtga aacaatctat ttgaacacct tatatgcaaa
    38221 agattttgtg gtcaattcag gtaaaacaat tgcacagcta ggaaaaactg ctttagaact
    38281 tggtaaatca gctctagcat ggactgctca tgcagcgaaa atgggattag caaccgcggc
    38341 ggaatttgca cattctgttg cagcaggagt cgctacagct gcaacatggg cttttaatgc
    38401 agcgttagca gttttgacaa gtccaataac atggattatt gcagcaatcg cagctttgat
    38461 tgctatcggt gtcttgctct accaaaactg ggacactgtt gttgagtttg ctaaaactgc
    38521 atggcaagga ctatgtgatt ttattagtgg tatttgtcga gctattggcg aatttttcag
    38581 tggtctatgg acaaaactac aagaaatctt tgagccgata ggtcaatggt ttggcgagaa
    38641 gttccagcaa gcatgggatg ccattgtcaa catcttctct ggtatcggag agtggttctc
    38701 tggtgtattc caaggtgcat gggacgctat cgttaatatc ttcactccaa tcggctcatg
    38761 gtttggacaa cgttgggcag atgtgactag tgctttggct aatatcgggg catggtttac
    38821 tgacatattc caaaaagcat ggactggtct aacaaacatc tttagcaaac taggtttatg
    38881 gtttggcgag agatgggcag atgttacaag tgttcttgcg aatgtatctt cttggtttgg
    38941 gaatatgttt actagtgctt ataatgcagt caagaacgcg tttagttcaa ttggtggctt
    39001 cttcagcggt gtatggtcaa cggttcaaag catatttgtc aatgctggac aaaaggttgg
    39061 tagcgctgta ggtggagcgt ttaagagtgc ggtcaatgcg gttcttggaa cgattgaaaa
    39121 tgtagtcaat gacttcatcg gaatgattaa tggagtttta ggcgttgtca gaaacttacc
    39181 tggtctagga tgggttggta gtgtaagcac agttagcctc cctcgtcttg cccgtggtgg
    39241 tatcgtcgat agtccaacaa tcgccatgat tggtgaagct ggtaaagagg cggtcgtacc
    39301 acttgaaaat acaggattta tccaaacact tggacgagta gtcagcagtg cggtagtaaa
    39361 tgccatggct ggtattagtc cacaaggtgg tttttctagc gacggcgaca tcgttattca
    39421 aatcgcaggc catgagttcg gacgggtagc tatccaagaa atcaacaagg aacatgaacg
    39481 agcaggtcaa accttgctca agatttagga ggttaaatgg cacaattgac aatcaatggg
    39541 gtggctgtga agcctcccaa atcttttcaa gtcggtattc aagatatcga tggagagaca
    39601 gggcgtaatg ccaatggcga catggtgcgt gaccgtatca cgaccaaacg caaactagac
    39661 tgtgaatggg gtatgatgac tcagggagaa ataagtcagc ttttacatgc tgtatcatct
    39721 aaattttttg aggtatctta tccagacccc atggatggcc aagtcacaaa gactttctat
    39781 gtcggtgata ggacagctcc tagctatacc tttactgaga agcttaaacc ttggtctggc
    39841 gctaaattta atctggtaga gaggtaagaa aatggacgct ttaactagac gacaatttga
    39901 cagagccatg tttgccaagg aaaggacgct ggctattcgt gttggtgaat atgcttcacg
    39961 ggatatcaaa gaggctagtt ttgagtatgg ctacatcaag ggcgatactt ataagcctgg
    40021 tggaacctgc gctggtagcg gtaaaattac ctttaccagt atcattacca cgttcaataa
    40081 gctggatacc ctgcaccctg agattggtct actggttggg gatacctacc agtgggtcaa
    40141 gatgggggaa tacttcatca acgatattga gattgaccga aaccgcaaca caaccacact
    40201 tgaacttatg gacggtatgt ttaagctcaa tcgtgagtac gtgacggatt tgcatttccc
    40261 agctgaagta cgagaggtta ttcaggaaat ctgcctgaaa acaggcattg agttagcgaa
    40321 tgactatttc ggaatcagcg ctatgcgtta ccatatcgag caagttcctg aaggtaagaa
    40381 actttcgttc agggatatgc tgagcgctat gactcagatg attgggatgt cttgcttctt
    40441 caaccgagaa ggaaagatgg aaatccgtga tttgaccgag tccaacatca cgattaacgc
    40501 tgacagttac ttcttgcatg gattgaccaa gagtgaaatc gagtatcaga tagctggtat
    40561 cacttgtaag acggataaga agtctctgac ggtcggtatg acaacaggtc ggtctttgga
    40621 acttgataat gtcttcataa cccagagcgc tttaaatgac ttgtattaca aactgaaaaa
    40681 cctaacttac tatccgtata atctcaacta ccaaggacat ttgttacttg aggttgggca
    40741 gtgggtaacc attcagacca acaagaaaga gacttttaaa gttcctgtct taagtcagag
    40801 ctttatcttt aaaggtggtc tgagaggtcg tatcagtgca gatagtaagg ctggaaacga
    40861 tacccagtat tcttacgagg gtacgattac caagcagatt aagcaacaag atggctttga
    40921 agcgaaaatc caagcgcaga ttgaagcagc agataaagat tttgaccaaa aggtcgacaa
    40981 aatcaaaaaa gactttaacg atcaagtaga actggccaaa gccagagctg aagaagtcaa
    41041 gagagaactg tctgacacta tcaatcagcg ctttaatagc tttgacaacg ggccattgaa
    41101 agaagctaag cgcaaggctg aggaagcttt gcgaaatgct ggcgcaagta gttctcttgc
    41161 tcaggaatcc aagcggattg ggctggattc tgttgctaga cttgaagcgt ttaagtcgca
    41221 gactacgagc gcacaaacgg ctctgtcggg tgacttggat gttctaaaac gaactatcgc
    41281 aaacgatatt cgaccgaagc aagcacaggc tgaagctgag attgccaagc aagttgaagc
    41341 acttagccgg actaaaaatg aactggatgg cgcaagtacc ctgcttgcac aggaagctaa
    41401 gcggattgag ctggattctg ttgctagact tgaagcgttt aagtcgcaga ctacgagcgc
    41461 acaaacggct ctgtcaggtg acttggatgt tctaaaacga actatcgcaa acgatattcg
    41521 accgaagcaa gcacaggctg aagctgagat tgccaagcaa gttgaagcac ttagccggac
    41581 taaaaatgaa ctggctggcg tgaagtcagc gcaagcgacg tatgaggaga cgacgactcg
    41641 tagactgtca gaactgacca acttggccaa tggtaaagcc agcaagtcag aactcacgca
    41701 gacagctgag gagctagcta gtcggattgc gagtgtgcag gcatccggtc gaaatctatt
    41761 cttgaactca ctattcaagc aggatatttc aaaaacagga atttggacaa cgagtacata
    41821 tacggctact atcgatagcg aaagtaagta tcttggatat aacgctctta aaattatagg
    41881 tctgaatcca tctggccgtg atggagggaa tcccaaggtt acttatccag ttctgggtca
    41941 attcgggaaa gtaattcccg gaagtacgac taatcaagat gtaaccatta gtttttatgc
    42001 taaggcaaat aaaaatggaa taatgctaag atctcgatta gggaatatcg gatataaaac
    42061 tggaaatgtg acattgtcga cagaaattaa acgatatgtt gtccatattc caaaaggttg
    42121 gacaaacgaa tccaagcaga ccacaaatga atggttgttc aatttcaacc aggaaggaac
    42181 cgtttggatt tggatgccga agtttgaaat aagcgatgta gatacttctt attcagaagc
    42241 tcctgaagat atagaaggtc agatttcaac agttgaatcg acctttaaac aacgagtcaa
    42301 ctcgctcgaa gctggtgtga atcgtctgac tgaaggcctt agaaccaaag ccgatatcag
    42361 cgcactcaac gtgactgctg aaaatatccg gcaatctgtg aagagtcttg agacagacac
    42421 gcagaacaag ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ccggctctat
    42481 ccgtcaggaa atcctgaacg caaccaagga taaggcagat aagactttag ttgtatctga
    42541 agctgggaaa ttgcgtgaag aattttcaaa aatgaaggtg ggaggccgga atctatggat
    42601 aaaatccaag acggttggag ctgtaattga aaaattacct gaaaaccatg tcacaggtca
    42661 aaaagaatgt tataggttag agaacaactc tactttaacg ttcaaccttg aaccagattt
    42721 cagctcaagg ttgtatcaaa aagttacttt tagcgcttgg atcaagtacg aaaatgtagt
    42781 ccaaggtcga aacttttgga atgtatttaa ttgcttcaaa cattatcttt ttagaaaaaa
    42841 tagtgagacc ggagtacaga gtggtccaga ttatgctacg cttggtatgt ataaaggttc
    42901 ggcagattgg aaatatatta cattcactta tgactactct gaaaaaacaa attttgatca
    42961 attgaagaca tcattgcgat tcaatcttga aggtgctaca agcggtacag cttgggtaac
    43021 aggaatcaag gttgaaatcg gtagtgtggc gacggactgg tcaccagcac cagaagacgg
    43081 agaaaatgag cttttagtcg ctaaaaccga gttcaagagg acagctgatg gcctatctac
    43141 taagatggca gcagttgaga gctatgttgg tcaagacggt cagcgacagg aagccctaca
    43201 gcgctatact cgtgaggaaa gcacgagaca agcgacagca gtccgtgagc tggtcaatcg
    43261 tgatttcgtt ggtaaggcta cttatcaaga agatgttaag ggtatcaatc agaggattga
    43321 agctgttaaa actagtgcga ataaagacat cgctagtcaa atcgctagct atcgtcaatc
    43381 tgtagatggt aagttcacgg atatttcaag tcagataact acttataagc aagatgtggg
    43441 cggtcaaatc agtggtctat caaatagact tacaagcagt gagcaaggaa ccactactca
    43501 gatttcaaat atttcaaatc ggataaacag taataagcaa ggcacagata atcagatttc
    43561 aaatttaaag actcaggtcg ctacaaacaa ggataatgct gaacgacaaa tgggtagaat
    43621 atctgatcag gtttctgcaa acaaagcgaa tgctgatagt caatttgcga atgtgaccaa
    43681 tcaactagcg cgaaaagtag agactactga cttccagcgt gttaaggaaa ccagtaaact
    43741 ttacgagcga attttgggca atactgaaaa tggaattgcg gataaggttg ctcgcatggc
    43801 tctgactaat caactgtttc aggttgaggt tgggaaatat agtgtaagcg gccctaacct
    43861 cattaagaat agtgatttta aaaatgctac gaatgaatgg ggctcaactc aaaatttagg
    43921 aagattggtt aagcatagct tttatcacaa cgggcagaaa gaccttatgc gtttaagtaa
    43981 tgcaactaaa aacgaaaact ttttgtatag tcaccgtttt aatcttgaac gaaatactga
    44041 ctatgtactg aattttagag gatttaacaa cagtgctctc gcaagctatg atgtttatat
    44101 tttgggacga agagcaggcg agagcgatgg attcacaatc gttaagaaag ttgttagcag
    44161 caagaaacta tctacctcta gatgcgaaga tgtctcagta acttttaatt ccggagaaat
    44221 ggataatgct tacattcgtt ttgataacaa tggctcatca tcaggaacag ctgatttgta
    44281 tattacagaa gttgacttgt acaaaggtta taaacctaga acatggcaac cacatccaga
    44341 agatgcagtc gcagatgcga ataagaagct tgaagcaacg caaacaaaaa tgactcaact
    44401 agctggctca tgggtagttg aaaacatcaa ctcggctgga gatatcatct ctggaatcaa
    44461 tcttggcgcc aatggacata accgcttcgt tgggaaattg acccacatca ctggagagac
    44521 cctgattgac agagcagtca tcaagtctgc catggttgat aagctgaaaa cgggcaattt
    44581 tgaagctggt tcggtcacga ctacgatatt agacgctgaa gcggtaactg ctgagaagtt
    44641 gaaagttgac gatgcgctta ttagaaaatt aactgcaaat gatgctttta ttgaccgact
    44701 gacatctaaa cgtatcttct ctactaaggt tgagtccgtc atttctagtt caaccttcct
    44761 agaagcctat caaggtcgaa ttggtggatt cacacttggt caatttgacc agggtggcgg
    44821 tcgctggatt tcaggtgtca atcagttctc tgttggtatg gggaatggtg ccgggcatgg
    44881 agtccggaca gccttctggg cgaactgggg aaataattgg aactatgccg gacctaaagc
    44941 atggaacgtc aatactgatg ggaaaatgta ctgtaggaat gaagtcggtt tttatgatca
    45001 agtggatttt tcgaattcat cgagagcaaa cttctatggg aatactactt tttctcgttc
    45061 tcctgtgttt tcaaatggta tcgaacttgg aagtaaagat gtgcttggtg atggttggaa
    45121 tcccaaaggc ggaaggaatg cggttgtttg gtggaatcag gtcggtagcg gtagcgtgaa
    45181 gtattggatg gaacaaaaat cagacagacg cttaaaagag aacatcacag atacagctgt
    45241 gaaagccttg gacaaaatca acagattaag aatggttgca tttgatttca tcgaaaataa
    45301 gaaacatgag gagattggtc taatagctca agaggctgaa accatcgttc caagaattgt
    45361 ctcacgagat cctgagaatc cagatggcta tctgcatatt gactataccg ctttagttcc
    45421 ttacttaatc aaggctattc aagaattaaa tcaaaaaata gaaaaaatgg agaaaacaat
    45481 agcatgaata acaacatgtt gaccaatatc gcactttaaa gcaattcagg agcttgctct
    45541 tgaaaataga aaacgaacac acagattgga gaacttagaa aatgaacaca gaacagctta
    45601 accaagcctt acaaatgaca attagtgaaa tgtcaacaac ttcaacaaat tcgatgatta
    45661 caaataatat cttgagtatt cagttggatg agcaaaggga agggaatcaa agacttcaag
    45721 cacgagtgga tgagctggaa gctctgcttg atgaacaaac taaaccagca gacaaaggag
    45781 aatagacatg gcagaaacaa atcaaaacac agataactta ctagacctta caaaaatcac
    45841 agaaccattt gatcttgcga gtgctttgcg ctacatgaaa gaaaatggag agttcattcg
    45901 ttgcaagaat gtaagcgatg acttctatat gtatcgtgat gttcaaaaac gtcctgtgat
    45961 cgtaaatggc cgtcgccaac tcaaggatgt tgaaaccgtt tgggcgttca accagtgggg
    46021 tggtacaatc gcaacaatca acgtcgccgt tctgttgaat catgaattct atatcatgaa
    46081 atttgatgca gagggcaatc ctgactggac ggatccaacg gtaaaaccta aagaatagga
    46141 ggtgtgtatg ccaattgaag aagctgaaaa aatcgctcaa agtcaggtag cttgggcgat
    46201 tttgtttatc ttgcttttct ttattatcat tcgatatctt atcaagactt cggacaagcg
    46261 agagaagaag attatggatt tgcacgagca atcaaaggcc gactctaata gacgagaaga
    46321 gcgtttgatg actcacctag aaaagaccac tacagaatta accacaatca ctcacgcggt
    46381 cggagacatt caaaaagaaa tggttcgcat gaacgaccgc atggaagaaa tcgaaaaagg
    46441 agaataacaa atgcaacaaa ttactgaaat cattactaat ggagcaatca gcatccttgt
    46501 tattttggct ggtatcgcag tcaaggcagt caaggactac ctggttcaaa aaggtggaga
    46561 aaagaccatc aaaatcgttg aaatcttggc caaaaatgca gtaaatgccg ttgagcaagt
    46621 agctgctgaa actggctaca agggagatga aaaactggca caggctcgcg ctaaagtccg
    46681 tgctgagctt acaaaataca atattagcat gactgacaaa gacttagaca ccttcgtaga
    46741 gtcagcagtg aagcagatga atgacgcatg gaaaggacga tagggaatgg atatcgatag
    46801 aaacagacta cgtacaggct tgccacaggt tggggtgcag ccttatcgac aagtacacgc
    46861 ccattcaaca ggcaaccgta actcaaccgt acagaatgaa gcggattatc actggcggaa
    46921 agacccagaa ttaggttttt tctcgcacgt tgttgggaac ggtcgcatca tgcaggtagg
    46981 acctgtgaac aacggaagtt gggatgttgg gggcggttgg aatgctgaga gttacgcagc
    47041 ggttgaactg attgaaagcc attcaactaa agaagagttc atgacggact accgcctcta
    47101 tatcgaattg ctacgcaatc tagcggacga agcaggcttg ccgaagactc ttgatacaga
    47161 cgacttggca ggtatcaaga cgcatgaata ctgtaccaat aaccaaccaa acaaccactc
    47221 agaccatgtg gatccatatc catatcttgc taaatggggc attagccgtg aacagtttaa
    47281 gcaagacatc gaaaacggct tgagagctgc aacaggctgg cagaaaaatg gcactggcta
    47341 ctggtacgta cactcagacg gctcttatcc aaaagataag tttgagaaaa tcaacggtac
    47401 ctggtattat ttcgatggct caggctatat gctttcagac cgctggaaga agcacacaga
    47461 cggtaattgg tactactttg accaatcagg cgaaatggcc acaggctgga agaaaatcgc
    47521 tgagaagtgg tactattttg atgtagaagg tgccatgaag acaggctggg tcaagtacaa
    47581 gaacacttgg tactacttag acgctaaaga aggtgctatg gtatcaaacg ccttcgtcca
    47641 gtccgcagac ggaacaggct ggtactacct caaaccagac ggaacactgg cagataagcc
    47701 agacttcaca gtagagccag atggcttgat tacagttaaa taaatagaaa ggaaactttc
    47761 taaattgttc tttcaccgca ggctcaggct tgcggttttt ttgttttaaa aaaggggcaa
    47821 aaaaggggca aaagtgtcgt aaatctctgt aaaatgatgt aaaaacattt atttaaaagc
    47881 tcaaaatata gctgttttaa aaggtattgt aagatatagt aaaacgatgt aaaggtattt
    47941 ttaaatgcgg atgaattata aaaccacgaa tcctatgtga ctcgtggttc ttttttataa
    48001 actggtagag tgttttggtt gtactttttg ttcagggtca atgtagttga tagcgttgtt
    48061 gacagcagtt ggagcttccc ctagacctgt cgcaatcaga tcaatttttc cgtcatagta
    48121 gcagcagtca ccgatagcat agatacctgc ttggctggat tcttgtttgc tgttgacgat
    48181 aatcttgtga cggttgaggt cgagccccca gtttttaagg ttaccgacag aagatttgaa
    48241 accatagttg acaaagaggt ggtctaggtc aatggtttca gtttcatcag atttgacttt
    48301 tgtgatttca agtttatcaa gcgtttttcc atctccaagg agttggctag ggacgaatgg
    48361 tgtcttgatg gttacagatg attcttgcaa ggcttgaaca ctgtgttcca aggcacggaa
    48421 attatctctg cggtgaacaa gggtagttgg tgcgattttt tcaaaagcca aagtccaatc
    48481 cacagccgag tctcccccgc caagaatcgt cactttctta ccagcgtatt gctgaatgtt
    48541 agaaacgtgg tagtggatat tttcatagcc ctcaacactt tcaagttcca gcggacgtgg
    48601 tttgaaggca ccgccaccca tagcgatgat aactgtttta gtcaggtgac ttcctttaga
    48661 agttgtgatg gcaaattctt cttcttgttt gtcaatctca agaaccgttt cattgagatg
    48721 aataggggta tcaaatccat ttagctgttc aatcaagcgg ttagtcaact cttctccagt
    48781 caggtttggg aagcctggta cgtctaggat ttccttttca gggtagagaa tagcaggttg
    48841 tccacctagc tggggaagag agtcgatgat ttgaaccttg gcttggcgta ggtgggcata
    48901 aaaggctgca aaaagcccga caggaccacc acccacaatg gtaatatcat agagttgaga
    48961 catagtttct cctttgtttt ttctagtcag tttattttat catatttttg ttcaatgtaa
    49021 aatggactag gatagggaaa aaaatgccag aaaatggtat aataggacga aagtgttttg
    49081 atagggagga tatcagggat gaattttcaa caattatcca atctgcaata ttggaccagt
    49141 ttgtttgcaa gtccatggac gatagctatc aatctgattg atattttgat tgttgcttat
    49201 attttatacc attttacaaa agctattgca ggaaccaaga ttatgatttt ggtacgtgga
    49261 gttttggtgt ttattttagc tcaaatcctt gcaaatatga ttggtttgac tacgatttct
    49321 tggttaatca atcaaattat tacttatggg gttattgcgg cggttgttat cttctctcca
    49381 gagattcgga ctggtttgga acgtttggga agagcgacag attttttttc caatgcccct
    49441 attagtgctg aggaacagat gattcgtgcc tttgttaagt ctgttgaata catgagtcct
    49501 cgtaaaatcg gggccttggt tgctattcag cgtgtacgta ccttgcagga gtatatttcg
    49561 acaggaattc ccttggatgc taagatttct gcagaacttc tcattaacat ttttattccc
    49621 aacactcccc tacatgatgg tgcggtgatt atcaaagaag aacgtatcgc tgtgacgtct
    49681 gcctatctgc ccttgacaaa aaacacaggg atttccaagg aatttgggac cagacaccgg
    49741 gcggctatcg gtttatcaga agtctcagat gccttgactt ttgtcgtatc agaggaaacg
    49801 ggaggaattt cgataaccta taatggaagg tttaagcaca acctaacact tgatgaattt
    49861 gaaacagaat tacgtgaaat cttacttcca aaagaggaag tgggtcttag ttttaaagaa
    49921 cgattgctag gaggatggaa acatgaaaaa aaatagttta tatatcatat cctcactctt
    49981 ttttgcttgt gtcttatttg tctatgctac ggcgacgaat tttcaaaaca gtaccagtgc
    50041 taggcaggta aaaacggaaa cctatactaa tacagtaaca aatgtcccta ttgacatacg
    50101 ctataatagt gataagtatt ttattagcgg ttttgcttca gaagtatcag tggtcttgac
    50161 tggtgcaaat cgcctatcgc tagctagtga aatgcaagaa agtacacgta aattcaaggt
    50221 tactgctgac ctaacagatg ccggtgttgg aacgattgaa gttcctttga gcattgaaga
    50281 tttacccaat gggctgaccg ctgtggcgac tccgcaaaaa attacagtca agattggtaa
    50341 gaaggctcag aaggataagg taaagattgt accagagatt gaccctagtc aaattgatag
    50401 tcgggtacaa attgaaaatg tcatggtgtc agataaagaa gtgtctatta cgagtgacca
    50461 agagacattg gatagaattg ataagattat cgctgtcttg ccaactagcg aacgtataac
    50521 aggtaattac agtggttcag tacctttgca ggcaatcgac cgcaatggtg ttgtcttacc
    50581 ggcagttatc actccgtttg atacaataat gaaggtgact acaaaaccag tagcaccaag
    50641 ttcaagcaca tcaaattcaa gtacaagcag ttcatcggag acatcttcgt caacgaaagc
    50701 aactagttca aaaacgaatt aaaaatagaa aaggatttta taacaatggg taaatatttt
    50761 gggactgatg gagtccgtgg agaagctaac ctagaactaa caccagaatt agcctttaaa
    50821 ctaggacgtt ttggaggcta tgttcttagt caacatgaaa cggaagcgcc gaaagtcttt
    50881 gtaggacgtg acacacgtat ttcaggggaa atgctggaat cggccttggt ggcaggtctc
    50941 ctttcagtag ggattcacgt atacaaactt ggtgtccttg caacaccagc agtagcttac
    51001 ttggttgaaa ctgaaggagc aagtgccggt gtcatgattt ctgctagcca caacccagcc
    51061 cttgataacg gaatcaagtt ctttggcggt gatggcttca aactagatga tgaaaaagaa
    51121 gcagaaattg aagccttgct agatgctgag gaagacactc ttcctcgtcc aagtgcagaa
    51181 ggcttaggaa tcttggtaga ttatccagaa ggcttgcgta agtatgaagg atatcttgtt
    51241 tcaactggaa ctcctcttga tggaatgaag gttgccttgg atacagctaa tggagcagct
    51301 tctaccagtg cccgtcaaat ctttgcagac cttggtgccc aattgacggt tatcggggaa
    51361 acaccagacg gtcttaacat caaccttaat gttggttcaa cacatccaga agcccttcaa
    51421 gaagtggtca aagaaagtgg gtcagctatt ggtttggcct ttgatggaga cagtgaccgc
    51481 ttgattgctg ttgatgagaa tggtgacatc gtcgatggtg acaagattat gtacatcatc
    51541 ggaaaatacc tttctgaaaa aggacaattg gctcaaaata caattgtgac aactgttatg
    51601 tctaaccttg gtttccacaa ggccttgaat cgcgaaggta ttaacaaggc agttactgca
    51661 gttggtgacc gctacgttgt tgaagaaatg agaaaatcag gctacaacct tggtggtgaa
    51721 cagtctggtc acgttatctt gatggattac aataccacag gtgatggtca attatcagca
    51781 gttcaattga ctaaaatcat gaaggaaact ggtaagagct tatcagagtt ggcggcagaa
    51841 gtaacgattt atccacaaaa attagttaat atccgagtgg aaaacgtcat gaaggaaaag
    51901 gccatggaag tgccagctat caaggccatc atcgagaaga tggaagaaga aatggcgggg
    51961 aacggccgta tccttgttcg tccaagtgga acagagcccc tcttgcgtgt tatggcagaa
    52021 gcgcctacaa cagaagaagt agactactat gttgatacca tcacagatgt agttcgtgct
    52081 gaaattggga ttgactaaat cctagaaaac tagatgaaaa taaaaaatta tgatacaata
    52141 gcttataata ttgtagccga tggagaaaga catgaatctt aaacgtgaac aagaatttgt
    52201 tagtcagtat cattttgatg cgcgtaattt tgaatgggaa aatgaaaatg gagctcctga
    52261 aaccaaggtg gatgtgaatt tccaattgct ccaacatgac caagaaaatc aagtgacttc
    52321 cttgattgtc atcttgagct ttatgattgt atttgataag tttgtcatta gtggaacaat
    52381 ctcacaagta aaccatatcg atggccgtat tgtcaatgaa ccaagtgaat tgaaccaaga
    52441 agaggtggaa accttggctc gtccatgttt gaacatgctc aatcgtttga cttacgaagt
    52501 gactgaaatt gcattagact taccaggaat taatttggag ttctaatatg aaattagctg
    52561 ttttcacaga ttcctctgct tatctcagtg cagagacctt gcaaagagaa gacttgtttg
    52621 tcttggatat tcctgtcaat attgatggtg aggaatatgt cgaaggcatc aatctgtctg
    52681 ctgaggaatt ttaccaaaaa atggctcagg cttctgaatt tcctaagacc agtcaaccaa
    52741 gtattgccaa gttagatgaa atcttaactt cgctcaaaga acaaggctat acacatgcct
    52801 tggggctttt cctatcttct ggaatttcag gtttttacca aaatatccag tatatggtcg
    52861 atgactatga gggcttaacc attgctttcc cagacacttt gattacaagt gctcccctag
    52921 gcatcatggt tgaaagcgtc tttaattggc gtgatcaggg cgatgatttt gccagcattc
    52981 aggataagct agccattcaa atcagccgta cgtcagcctt tatcatggta gatgacttgg
    53041 atcatttggt aaaaggtgga cgcctttcaa atggggctgc cattttgggc aatttgctta
    53101 gcattaagcc aatcctttat tttaacgatc aaggtgtgat tgaagtttac gaaaaagttc
    53161 gtactgaaaa gaaggccacc aagcgcttaa ttgaaattat caaggaaaca acggcttcag
    53221 gtcaataccg ggtcattgtc attcatggga atgctcctga aaaggctgaa gaattgcgtc
    53281 agcacttgct tgattttggc ttgggttcgg atgtttcact tgctacattt ggtagtgtca
    53341 ttggaacgca cctaggagca ggaagtattg ctctgggtta tattccagtg atttagttgg
    53401 cgcttctagg ctagttaaga tgccttgtat cttagaaatt gaacacggac tacctgcctc
    53461 ttgaaaaaag atgcctgtct tgcctttcgt ggaaagtcag tgccattccc tatttttcag
    53521 aggcagctaa ggtcctttgt atcttgataa ttgaacacgc ctggaaccct gtgtgaaaaa
    53581 gatagttctt ccaagaagta gacacttctt gattggaatt cctattttca ctttgtgttc
    53641 ttacggactt tgtatcttag acaggagtag agatgagtat tcgagtaatt attgccggtt
    53701 ttaagggaaa gatgggccag gctgcttgtc agatggtatt gactgatcca gacttggact
    53761 tggtggcagt tttggatcct tttgagtctg agtcagaatg gcagggtatt cctgttttca
    53821 aggataaggc tgatttagct ggttttgaag cggatgtctg ggtagatttt actactccag
    53881 ctgttgccta cgaaaataca cgttttgctc ttgaaaatgg ctttgctcca gtagttggaa
    53941 cgactggttt cacgagtgaa gaaattgcag agctaaaaga attttctcgt gcccaagact
    54001 tgggtggcct gattgcccct aactttgcct tgggtgctgt cttactcatg caatttgcga
    54061 cgcaggctgc caaatatttc ccaaatgtgg agattattga gctccatcat gacaagaaaa
    54121 aggatgctcc gagtggaaca gccattaaaa cagctgagtt gatggcagag gttcgagagt
    54181 ccattcagca aggtgcagca gatgaggaag agctgattgc tggtgctcgt ggtgctgact
    54241 ttgatggtat gcgcatccac tcagttcgtt tgccaggctt ggtagctcat caggaagtca
    54301 tctttggcaa tcagggagaa gggttgaccc tccgtcatga ctcctatgat cgcatctcct
    54361 tcatgacagg agtcaatttg ggaattaaag aagttgtcaa gcgtcatgag cttgtctatg
    54421 gattagaaca cttattatga gattaatgca aatgccttct gaatttcaga aggctttacc
    54481 agtattagaa aaaattaaag aagcaggctt tgaggcttat tttgttgggg gctctgttcg
    54541 agatgccctt ctccatagcc ctatccacga tgtggatatt gcgacgtctt cttatccaga
    54601 agagaccaag cagatttttc cgcgaacagc cgatatcgga atcgagcatg gaaccgtctt
    54661 ggtcttagat ggggatgagg agtatgaggt aacaaccttt cggacagagg atgtctatgt
    54721 ggactatcgc agacccagtg cggtttcctt tgtgcgctcg ctagaagaag acctcaaacg
    54781 ccgtgatttc acagtcaacg cctttgcctt ggatgagaca ggagaaatcg ttgacttgtt
    54841 ccatggttta gaagatttgg aaaagcaagt cttgcgagca gttggagtgg ctagtgagcg
    54901 tttcaacgaa gatgctttac ggattatgcg tggtttccgt tttcaggcta gtcttggttt
    54961 tgcacttgag ccagaaacat ttaaagctat gaagaccttg acgccgcttt tggagaaaat
    55021 ttctgtagag cgtaccttcg tcgagtttga taaactcttg ctggctccat tttggagaag
    55081 gggcttggct tccatgattg agagtcaagc ttatgactat ctccctgata tggcatctag
    55141 ccaggacaag ctcaacagac tgtttgattt ggagactgat tttacttttg aatcctctga
    55201 acaagcctgg gcggctttac tatgggcttt ggagattgaa aatgcgcagt catttttgaa
    55261 atcttggaag acctcacgcc agtttgccaa gcaagttcag gatttgctga ttattttggc
    55321 tctgcgtgaa aatggagaat tgagtaagcg tgattgttat cgctttgact tggatttact
    55381 tttacaggct gaaaatcttc gtcaagctca aggaaaagaa gtcaacccac aagtcattaa
    55441 agaaacctac cagagcttga ctattcatga taagaaagaa atccaaatca acggcggtat
    55501 tttgatcaag gaatatggct atcagccagg cccagacttg ggagagattt taacagagat
    55561 tgagtttgcc attgtcgatg gagaattgga gaataatcgt gaagccatcc atgcttacct
    55621 gagggagaaa aaatgagtga ttttatcgtt gaaaaactaa gtaaatccgt tggtgacaag
    55681 accgttttta gggatatttc ctttattatc catgacttag acagaattgg tttaatcggt
    55741 gtcaatggga ctggcaagac cacccttttg gacgtccttt ctggtgtttc tggatttgat
    55801 ggggatgtca gtcctttttc agctaaaaat gattaccaga ttggttactt gactcaggat
    55861 cctgattttg atgatagaaa gacagttttg gatacggttc tatctagtga actcaaggaa
    55921 atccagctca ttcgtgagta tgaattgatt atgctcgact atagtgagga caagcaggcg
    55981 cgtttggaac gtgtcatggc agagatggac tctctccaag cttgggaaat cgagagtcag
    56041 gtcaagaccg ttcttagcaa attgggcatt caagacttat ctactcctgt tggggaattg
    56101 tcaggtggtc tgagaagacg ggtacagttg gcacaagtct tacttggcaa ccacgacctt
    56161 ttgcttttgg atgagccgac caaccatctg gatattgcga ttattgagtg gctgaccctc
    56221 tttttgaaaa attctaagaa gaccgtcctt tttatcactc acgatcgtta tttcttagac
    56281 gctttgtcaa cacggatttt cgagttggag cgagcaggct tgaccgagta ccagggaaat
    56341 taccaggact atgttcgcct aaaggcggaa caggatgagc gcgacgcggc tcttcttcac
    56401 aaaaaagaac aactctacaa acaagaattg gcctggatgc gcagacaacc gcaggcgcgt
    56461 gcgaccaagc agcaggcccg tatcaatcga ttccatgatc tgaaaaagga agtttcaggc
    56521 agtagtgctg agacagactt gaccatgaac tttgaaacca gtcggattgg gaagaaagtc
    56581 atcgagtttc aggctgtttc ctttgcctat gaaaacaagc ctattttgca agattttaat
    56641 ctcttggtgc aggccaaaga ccgtatcgga atcgttgggg acaatggtgt tggaaaatca
    56701 accctgctca acttgattgc aggaagtctt gagccaacta aaggacaagt tgtgattggg
    56761 gaaactgttc gcatcgccta tttctctcag caaattgagg gtttggatga aagcaagaga
    56821 gttatcaatt acctgcagga agtggcagaa gaggtcaaga ccagtggcgg ttctacgact
    56881 tcgattgcag agttgctgga gcagttcctt ttcccacgtt cgacgcatgg aaccttgatt
    56941 gagaaattgt cagggggtga gaaaaaacgt ctttatctcc tcaaactgct tttggaaaaa
    57001 ccaaatgttc ttcttttaga cgagccaacc aatgacctag atattgcaac tttgacagtc
    57061 ttagagaatt tcttgcaagg ttttgcaggt cccgttttaa cagtcagtca cgaccgctat
    57121 ttcttggata aggtagcgac caagattctc gcttttgagg atggcaagat tcgtcctttc
    57181 tttggtcatt acaccgacta tcttgatgaa aaagcttttg aaacagatat ggccaatcaa
    57241 gtgcaaaagg tcgaaaagga aaaagtggtc aaggttcgag aagacaagaa acgcatgacc
    57301 taccaagaaa agcaggagtg ggcaagtatt gaaggtgata ttgaaacctt ggaaaaacgt
    57361 atcgctgcta ttgaagagga aatgcaggct aacggctctg actttggtaa gctgactact
    57421 ctccaaaaag aattggatga gaaaaatgaa gcactccttg aaaaatacga acgctatgag
    57481 tatctcagtg aatttgatag ttaagactat tcgaaaatca aagtgcaaac tatgtcggct
    57541 tcacattgcc gactcaagta cagcctgtga ccggcttcct aatttgcact ttgattttta
    57601 ttgagtataa aagaatagaa aaatcccgtc tcatgaaagg atttctctat tcttttttgg
    57661 tttcttgatg aaagatattt tgccaggttt cgtggcgacg ccagatactg gtatggatga
    57721 taccatctaa ctcatagcag atgagtttgg ttttttgact gatggaagta atttgaatgt
    57781 cctttatagc agaatttaac tcttttttgg tcttataagc ctctttatcc atctgctctc
    57841 catcttggcg aatatagaca aaatcatcag tcaagagttc ttctagttgg tttccttggt
    57901 caatcaattg ttcacgcata agcaattttt tatagacatt gtctaaaatt tcatcctcag
    57961 ggataggtgc tggttcgata tggacatcgg tatcaaagac gccaaaacgc tcctccagca
    58021 tagactcgac ctgatccgcg atttcatggc tttcaaaaac agacaagtca ggattcatct
    58081 ctagtgtaat atccaggtag atgttgctac cgtaggtgcg acctctttgc gatttgacct
    58141 tgctgatttt gggaatttcc atgatagcct tttggtagtc ctcgagcagg cggtcgtcaa
    58201 agccatctga aagactaaag gaagactcga tgaagatatc ataggcagtc ttcaagataa
    58261 agaaagtgat gatgatagca accagtttat ccacaatcgg ataattgaaa ctactagcta
    58321 ggatggcaat ggcggttcca agtgaggtaa cagcgtcaga aagattgtcc ttagcagctg
    58381 ccttcagcgc cttggagttg gatttcttac tgaggcgagt attgtagaga tagaccacaa
    58441 acataatcgc tgcagaaatg attcctagag ttgcaccaag aggatcaatg accgtttctt
    58501 cccgactgag aatcttttga atggtatctc ttagaacatc gaaaccgaca tagaacatga
    58561 tgatagaagt gatcaagctt gccaaatctt caatcttcca atgaccaaaa cggtggtcac
    58621 ggtctgcagg ctggcgcgcc atccgaatcc cgattaagag ggccacattt ccaatgatgt
    58681 ccgatacgtt attaaaacca tcggccacca aactggatga atgaaggaga tgaccagctg
    58741 ctaatttagc tgcagacaag atcaaatagg tcgaaatact gataatggct ccacgctcag
    58801 ctaacttgag atttgagata gattgcttca ttcaacttcc tttctagtca catagcattc
    58861 taccattata ctggttttca aggaaaaatt caaataaggc agtttttact ctttgaaaac
    58921 tccccaaaat ttggtataat ggtactactc aagggagtag ctggcagaaa cctgtgatag
    58981 tgtcgtcatt ccgaatttta tgctgaaaag tatgctttcc ggccctatct taaacagcga
    59041 gacttgttat gattaacagg tctctttttg tttgtcgtga aaagatatga cagaaagaga
    59101 gtctgttttg cacacaatgt caaggaggag acacatgtca aaagaacaaa aacgccaagc
    59161 gttttatact cagagccctg aagaggtctt gcaggctgtg gatgcgaccg agcaaggttt
    59221 gtcatcaagt gaggcggaaa agcgccttgc cgaatttggg cacaatgaac tcgaagaagg
    59281 cgagaaacga tcaatcttgg tcaaattcat cgagcaattt aaggatttga tgattatcat
    59341 cctagttgcg gcagcaatct tgtcagtcgt gacttctggt ggggaagata tcgcagatgc
    59401 cattatcatc ctagctgtgg ttatcatcaa cgctgccttt ggtgtttacc aagaaggaaa
    59461 agctgaagaa gctattgaag ccctcaaatc catgtctagt ccagttgccc gcgttcttcg
    59521 tgatggacac atggcagaga ttgactctaa agaattggta ccaggcgata tcgttgccct
    59581 tgaagcaggt gacgtggtac cagcggacct acgtttgata gaagccaact ctcttaaaat
    59641 tgaagaagca gccttgacag gtgaatctgt accagtcgaa aaagacttgt cagtcgagct
    59701 tgcgacagat gctggtattg gtgaccgtgt caacatggcc ttccaaaact caaacgtaac
    59761 ctatggtcgt gggatgggtg ttgttgtcaa tacaggtatg tacactgaag ttggtcatat
    59821 tgctggtatg cttcaagatg cggatgagac tgatacacca ctcaaacaaa acttgaacaa
    59881 cctttctaag gtcttgacct atgctatctt ggtcattgcc cttgttactt ttgtagtggg
    59941 tgtcttcatt caagggaaaa atccacttgg tgagttgttg acttctgttg cccttgccgt
    60001 tgcagccatt ccagaaggac ttcctgctat cgttaccatc gttctttctc ttggtactca
    60061 agttttggcc aaacgacatt ccatcgttcg taagttgcca gcagttgaaa cacttggttc
    60121 aactgaaatc atcgcttctg ataagactgg tacgctgact atgaacaaga tgacagtcga
    60181 aaaagtcttc tacgatgcgg ttctacatga ctcagctgat gatattgaac taggtcttga
    60241 aatgccacta cttcgttcag ttgtcttggc caatgatacg aaaatcgatg tggaaggtaa
    60301 cttgattggt gacccaaccg aaacagcctt tatccaatat gccttggaca agggctatga
    60361 tgtcaaaggt ttcttagaga aatatcctcg tgtagctgaa ttgccatttg actctgaccg
    60421 taagctcatg tcaacagttc acccattgcc agatggtcgt ttccttgtag cagtcaaggg
    60481 tgcgccagac caactcttaa aacgttgtct tcttcgtgat aaggctgggg atattgctcc
    60541 gattgatgag aaggttacaa atctcattca tacaaacaat tctgaaatgg ctcatcaagc
    60601 cttgcgtgtc cttgcaggtg cttataagat tatcgatagt attccagaaa atctcacttc
    60661 tgaagagctt gaaaatgatt taatttttac tggtttgatt gggatgattg accctgaacg
    60721 tcctgaagcc gctgaggctg ttcgtgtggc taaggaagcg ggaatccgtc caattatgat
    60781 tacaggtgac caccaagaca cagcggaagc cattgccaaa cgtttgggaa tcattgacgc
    60841 aaacgataca gaaggtcacg ttttaactgg tgctgaactc aatgaactgt cagatgaaga
    60901 atttgaaaaa gtcgttggtc aatactctgt ttatgcccgt gtgtctccag aacacaaggt
    60961 tcgtatcgtc aaggcttggc aaaaacaagg taaagtcgtt gccatgacag gtgacggtgt
    61021 caatgacgcg ccagctctga aaacagccga tatcggtatc ggtatgggaa tcactggtac
    61081 agaggtttct aagggggctt ctgatatgat tcttgcagat gataactttg cgactattat
    61141 cgtcgcagtg gaagaaggac gtaaggtctt ctcaaacatt caaaagacta ttcagtacct
    61201 actttctgct aatactgctg aagtattaac catcttccta tcaaccttgt ttggttggga
    61261 tgtcttacag ccggttcatc ttttgtggat caacttggta acggatacct tcccagctat
    61321 cgctcttggt gttgaacctg cagaacctgg cgtcatgaat cataaaccac gtggacgcaa
    61381 ggcaagcttc ttctcaggtg gtgttttgag ttctatcatt tatcaaggtg tactccaagc
    61441 agctcttgtt atgagtgttt atggccttgc gattgcttac ccagttcatg tgggtgacaa
    61501 tcatgctatt catgcagatg ccctaacgat ggcctttgca acccttggtt tgattcagct
    61561 cttccatgcc tacaatgtca agtctgtcta ccaatccatc ttgacagttg gcccattcaa
    61621 gtctaagacc tttaactggt ccatcttggt atcctttatc cttctcatgg caacaatcgt
    61681 tgtagaaccg cttgaaggaa tcttccacgt aaccaaacta gacttgtcac aatggggaat
    61741 tgttatggct ggaagcttct caatgattat catcgtcgaa atcgttaagt ttattcaacg
    61801 caaactcggt tttgacaaga atgcgattta agggaggttt cggatgtcag catatcaatt
    61861 accgaccgta tggcaggatg aagctagtaa tcaaggagct tttacggggc taaacagacc
    61921 aacagcaggt gcccgtttcg aacaaaactt gccaaaagga gaacaagctt ttcagcttta
    61981 ttcactggga acaccaaatg gtgtgaaggt tactatctta ttggaagaat tactagaagc
    62041 tggttttaag gaagcggctt acgacttgta taagattgct atcatggatg gggatcaatt
    62101 cggctcagac tttgtgaagc tcaatccaaa ttccaagatt ccagccttat tggaccagtc
    62161 aggtactgaa agcgtaagag tctttgagtc tgctcatatt cttctttacc ttgctgagaa
    62221 atttggagcc tttttaccaa gtaatcctgt ggaaaaggta gaagttttga attggctatt
    62281 ctggcaagca ggtgcagcac cttttctagg tgggggattt ggacatttct tcaattatgc
    62341 tcctgaaaaa ttggaatatc ctattaaccg ttttacgatg gaagtgaaac gccagttgga
    62401 tttattggat aaggaattgg ctcagaaacc ttatattgca ggcaatgact atacgattgc
    62461 agatattgct atctggtctt ggtatggaca gttagttcaa ggaaatcttt accaaggttc
    62521 tgcaaaattc ttggatgcct caagttatca aaatctagta aaatgggcag aaaaaattgc
    62581 caatcgtcca gctgttaagc gtggattgga agtaacttat acagaaatta aatagcaaaa
    62641 aagtcatctt cggatggctt tttgctacag ttgagggaaa gggtttgcag ttatcggctt
    62701 ttgtgctata attgctataa tatagtaaaa agcaagagga gtgtgaggaa gtggaaaaga
    62761 aaattgtgaa ggatatctta tttttatctc aagtgtctca gccggcaagt caggaggacc
    62821 tttatcttgc cagagatttg caggatacac tcttagcaaa tcgtgatacc tgtgttggtc
    62881 tagctgccaa tatgattggg gtgcagaagc gcgtgattat ctttaatctt ggcttggttc
    62941 ccgtggtcat gtttaaccca gtgcttctgt cctttgaagg atcttatgag gcagaagaag
    63001 gctgtttgtc cttggtaggt gtgagatcaa ctaagcgtta tgaaaccata aggcttgcct
    63061 atcgtgacag caagtggcag gaacagacca ttaccttgac aggcttccca gctcagattt
    63121 gccagcatga gctggatcac ttggaaggac gaatcattta ggaggaaagc aaatgaaacg
    63181 aatagtcttt gaacttattt ttatcgcaac gacctggtat atctttttac cgccccttaa
    63241 cctgaccagc tgggaatttc tcttcttcct ctgtgggcat ttgttagttg tggcaatctt
    63301 atttggcttt ggcaagggga taaaccttgt caaaacggtt catgtgcgcc acggtaaggc
    63361 ggaagctgcc ttaaatcttg agggtttcaa aatcaatcgg ttagggaaaa ttctgttagc
    63421 ttcgattgga ggaattcttc tcttggcagc tttggtttcc ttggtaactt ccagcatgtt
    63481 tcaggctaaa aattatgcca atgtagtcac ggttacggaa aaagacttta ctgaatttcc
    63541 taggagtgac accagtaagg ttcctatcct agatagaagt actgctgaaa aaattggaga
    63601 ccgctacttg ggttccctaa ccgataaggt gtcgcaatac gtagcggcag atacctatac
    63661 ccaattgaca attgatggga aaccttatcg ggtcacacca ctagaatatg cagaccctat
    63721 caaatggttt aacaatcaag ccaagggaat cggtgagtat atcaaggtgg acatggtaac
    63781 tggaaatgcg gatttggtgg acttgaagac accaatcaag tattcagact cggagtattt
    63841 taaccgtgat gtcaaacgtc acctgcgctt gaagtacccg accaaaatct ttaaaactcc
    63901 atcttttgag gtggacgatg agggcaatcc tttctatgta gcaacggttt accaaaagca
    63961 atttggactt gctgttcctc gtcctgcttc agtcattatc ttggatgcta caaatggaga
    64021 aaccaaggaa tacagcttat cagatgttcc agaatgggtg gacaggatct atccagcaga
    64081 ggaaaccatt gagcaaatca actacaacgg caagtacaag gacggtttct tgaatgccat
    64141 gatttccaag aaaaacgtga cccagactac caagggctat aattacttgt ctatcggtaa
    64201 tgacatctat ctctacacag gtgtgacgtc ggctaatgcg gatgagagta atcttggttt
    64261 catccttgaa aatatgcgaa caggagaaat cactaagtat agcttggctt ctgcgacaga
    64321 agaatcagcc cgtgaatcag cagaaggtgc tgttcaggag aaatcctaca aagcaacctt
    64381 cccaatcctc atcaacctca atgacaagcc tctctacatc atgggcttga aggacaatgc
    64441 tggcttggtc aaagagtacg ccctggtaga cgcagtcgag taccaaaatg ttatcgttgc
    64501 tactacagtg gaagagatgc tcagcaagta tgccaataaa aacgaccttg aaattgacaa
    64561 tgcaacgaca gaaagcatca atggagtagt agcagacctc aaatcagctg ttatcaaggg
    64621 agacactgtc tacttcttta aagttgatgg caagatatac aaggtcaagg cttcagtatc
    64681 cgatgacctt ccttaccttg aaaatggtaa aaccttcgaa ggtcaagtag gaaaagacaa
    64741 ttatctcaag acctttaagc tacggtaaaa ataggttttt ttcagaaagt atatgttata
    64801 ataaggtaaa ttaagcctaa tggaggacaa agaaatgggt ttttatttga tggttgcttc
    64861 aatgctactc ggactgctcg ctttgaagat aggtttttct cagttcaagg agaaaaaaga
    64921 taaattctta tctatcttaa caagtttagc tggcacagcc cttgttctcg tggctgtctg
    64981 gttaggatgg cccaaataaa tagaaaaacc tcggtcaaac cgaggttttt caaatgaatt
    65041 tcttggttgt ggctaaaaaa tatgctacac tatcaatatg aaaattttaa tcccaacagc
    65101 aaaagaaatg aacacagact tgccaagtat cgaggcaatt tctttaaaac cagaaagtca
    65161 ggccgtgctt gatgccttgg ctctctattc tgccagtcaa ttggagagtt tctacaaggt
    65221 atcagctgag aaagcggcgg aagaatttca aaatatccaa gctttgaaaa ggcaaactac
    65281 tcaacactat ccagccttga aactttttga tgggcttatg taccgcaaca ttaagagaga
    65341 taagctgacc gaggcggaac aagattatct tgaaaatcat gtcttcatta cctcggcttt
    65401 gtacggtgtt gttccagcct tgtcacccat ggctcctcac cgtttggatt ttttgatgaa
    65461 attaaaagtt gctggtaaga ctttgaagag ccattggaag gcagtctatg atgaagctct
    65521 gaagaaggaa gaagtgattt tctctctctt gtcatcagag tttgagactg tattttctaa
    65581 ggaaatcaga gcaaagatgg tgaccttcaa attcatggag gatagaggcg gtcagctgaa
    65641 gattcactca actatctcca agaaagcgcg cggggccttt ctaacagctt taatagaaaa
    65701 tcaagtacaa actgtggggg aagcacgtcg cttgaacttt gctggatttg tttaccgaga
    65761 agatttgtca caaccacagg gattggtttt tgtaaaggaa gtatagaaat cagatatttt
    65821 gtatttggca atatgtatca tcagctattt tagtttataa atgagaaaaa agcgaacaag
    65881 ctagtcttct gagcgtcaga aaagtagtct tgttcgcttt tattatgtta tactcttcga
    65941 aaatctcttc aagccatgtc agtgtcgcct taccgtatat atgttactga cttcgtcagt
    66001 tctatctaca acctcaaagc agtgctttga gtagcttgcg gctagcttcc tagtttgctt
    66061 tttgattttt attgagtgtt agttacttga tagcttcgac caagtcttga gcttgttttt
    66121 caagtgagtt taggactgtt tcttcaagaa ccaattttcc gtctgcccag gcagagtcat
    66181 taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg gataaatggc aagaggtctt
    66241 tgtagatagc gaaaagttga tcgtgccctg cattggctac agatgatact gtgacaaact
    66301 tgtcttgaag ggcagaaacg ccacgtgtat cagacaagtc aagggcacga gatagccagt
    66361 caagcaagtt tttcactgta ccagggatag agaagttgta gactggagag aaaatccaga
    66421 tagcatccgc aacgagaact gcttcacgag cagcagctac agctggatgt gttggaactt
    66481 ccaaatcttg gctgaagaga ggaagggctg aataatcaag gtagctaact tccgctttac
    66541 cagcaagtgc tttctcagct tcgagcgcca tttggtggtt gaaagaacct tgacgtagtg
    66601 atccgacgat aaataatact tttttagaca tgatgtgtct cctttttctt aaaatttcga
    66661 gaactctctc gttgttataa aatatattac aacaaaacaa aagaacttgc aagaaatttg
    66721 ctcagagttt atttgaaaat tgtaaaattt cggaaactct agtcatttgt gactgaaaaa
    66781 gtaagaactg tttcactttc aaaatcggtt ttgtttgaag ggagaaatag aattggttgc
    66841 tcaaagcaca gctttgaggt tgcagataaa gctgacatgg tttgaagaga ttttcgaaga
    66901 gtattcttat attcacttgt aataaagctt aatagatggt aaaatagacg agtgaaaaaa
    66961 agacaaaaca aagcaaaaaa taatctactg tggcagtatg gtctagggat gacgattttg
    67021 tttgtggtta tcagtgcttc ctttctgtat atggtttctc ttagcatgaa accctatcaa
    67081 acagctaaaa gtgaaggaga aaaattagct cagcagtatg caggattaga gcaggctgat
    67141 caggttgatt tatacaatgg cttggaatct tattacagcg ttcttggtcg taataaacag
    67201 caagaagcgc ttgctgtcct gattggtaaa gatgaccata agatttacgt ttatcagcta
    67261 aatcagggta tttcacaaga aaaagcagaa acggtttcta aggaaaaggg agctggcgag
    67321 attgacaaga taacctttgg tcgttatcaa gacaagccaa tctgggaagt taagtcagga
    67381 tctgattttt atctagtaga ttttgaaaca ggagcattgg tcaataagga gggcctatga
    67441 aactatccaa ccgtgtttta gaaatggaag aaagtgtgac tttggctgct ggagcccgtg
    67501 ccaaagcact gaaggctgag ggtagagata ttttgtctct aaccttgggt gagccagatt
    67561 tcactactcc caaaaatatc caagatgccg ccattgcatc gattcgagat gggcgtgctt
    67621 ctttttatac agtaacctca ggtctgccag agcttaaggc ggtggtcaat agctactttg
    67681 agcgctttta cggctattct gtagcgtcaa atcaagtgac agtcgctgcg ggagccaaat
    67741 attctctcta taccttcttt atggctgtgg tcaatccagg tgatgaagtc atcatcccaa
    67801 ccccatactg ggttagctat ggagatcagg tcaagatggc agaaggcgtt cccgtctttg
    67861 tttctgctaa ggaagacaat cactttaagg tgaccgtaga gcagttagaa gcagctcgca
    67921 ctgacaagac caaggttttg gtgctgaatt cgccatctaa tcccacaggt atgatttaca
    67981 cccgtgagga actcttggca attggaaact gggctgtaga aaatgatatt ctcatcctag
    68041 cagatgatat ctatggccgc ttggtttata atggtcatga gttcacaccg atttctagcc
    68101 tatcggaagc gattcgcaag caaacagtgg tcatcaatgg tgtgtctaaa acctatgcca
    68161 tgactggttg gcggattggt tatgccgttg gagaagcaga cattatcgct gccatgtcca
    68221 agattgcagg tcaaacaact tcgaatccgt cagcagtagc ccaatatgca gcagttgagg
    68281 ctctatcagg tgagcaagat actgtagaaa gcatgcgtca ggcctttgag gaacgtctta
    68341 ataccatcta tcccctcctt gcagaggtgc caggatttga agtggtcaaa ccacaagggg
    68401 ccttctatct cttcccaaat gtcaaaaagg ccatggagat gaaaggctac acggatgtga
    68461 cagactttac aactgctatc ttagaagaag ccgaagtggc cttggtaaca ggagctggat
    68521 ttggagcacc agaaaatgtc cgcctcagct atgcgacaga cctagacacg cttaaagaag
    68581 cagtcgaacg cttgaaagca tttatgggta gtgagaatga ttgatcattt tgagattaag
    68641 gtaaaggatt tacaaatttc agaaggattt tataggagtt ttctcgctcc tttggactat
    68701 aaattggctt ttaagactag ttctctaatt agttttctat ccccgaacag ccctcatcct
    68761 ggtggtgatt tttggctgac tcagggaaca caagatcctg ttcattttgc ttttttagca
    68821 gaaaataagg aagaagttca ggcttgttat gaggctggct tagaggcagg tgggcgagac
    68881 aatggggttc ctggttatcg aagtgagcat ccgatttatt atgctgcttt tatgattgac
    68941 ctggatggga acaatataga ggtggtttgc cataaagaat aaaaaagaaa aggaaaaata
    69001 atgacaaaac gtgtaacgat tattgatgta aaagactatg ttggtcagga agtgacgatt
    69061 ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg ctttcttaca attgcgtgat
    69121 ggaacagcct tctttcaagg tgtggctttt aaaccaaact ttgtcgaaaa atttggtgaa
    69181 gaagtgggac ttgagaagtt tgatgttatc aaacgcttga gccaagaaac gtctgtttat
    69241 gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg gctatgagtt ggacatcaca
    69301 gacatcgaag tgatcggtga atctcaagac tacccaatca caccaaaaga acacggaaca
    69361 gactttttga tggataaccg tcacttgtgg ctacgctctc gtaagcaagt agctgtgttg
    69421 caaatccgta acgctattat ctatgcaact tatgagttct ttgacaagaa cggttttatg
    69481 aagtttgaca gcccaattct ttcaggaaat gcggcagaag attctacaga actctttgaa
    69541 actgactact tcggaacgcc agcctacttg agccaatcag gtcagcttta cctagaagca
    69601 ggggctatgg ctcttggtcg tgtctttgac tttggtccag ttttccgtgc tgaaaaatca
    69661 aaaacacgcc gtcacttgac tgagttctgg atgatggatg ctgagtactc atacttgaca
    69721 catgatgagt cgcttgactt gcaagaagct tatgtgaaag ctcttctaca aggtgttctt
    69781 gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata cagaactctt gaaacgctac
    69841 attgcagagc cattcaaacg tatcacttac gatcaagcca ttgacctctt gcaagagcat
    69901 gaaaatgatg aagatgctga ctacgagcat cttgagcatg gtgatgactt tgggtcacca
    69961 cacgaaactt ggatttcaaa ccactttggt gtgccaacat ttgtcaagaa ctatccagca
    70021 gccatcaagg ccttctacat gaaaccagtt cctggaaatc cagagcgcgt gctttgtgca
    70081 gacttgcttg ctccagaagg ctatggagaa attatcggtg ggtctatgcg tgaggaagat
    70141 tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg atcgtacaga atatgaattc
    70201 taccttgacc ttcgtaaata cggtacagtt ccacacggag gatttggtat cggtatcgaa
    70261 cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg aagctattcc attcccacgt
    70321 atgttgcacc gtatcaaacc ataagaacag gaaaacgccc atgtggcgtt ttttcgaatt
    70381 ctagtgtttt tacttgcgta aaaaaatttt ttctagtata atagtttatt gtgagcgaac
    70441 ctcacttacc ccttgcaaag tcttggggtc attagaccaa aaggaggaac atatcaatgg
    70501 ctaaatacga aattctttat atcattcgtc caaacattga agaagaagct aaaaacgctt
    70561 tggtagcacg ttttgactct attttgactg acaacggtgc aactgttgtt gaatcaaaaa
    70621 cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt ccgtgaagga ctttaccaca
    70681 tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga gtttgaccgt ctttcaaaaa
    70741 tcaacgctga cattcttcgt cacatgatcg tcaaaattga cgcgtaagaa ggtaaactat
    70801 gattaacaat gttgtacttg tagggcgtat gacacgtgac gctgagttgc gttatacccc
    70861 atcaaatgta gcagttgcga cttttactct tgcagtaaac cgtacattta agagtcaaaa
    70921 tggtgaacgt gaggctgatt ttataaatgt cgttatgtgg cgccaacagg ctgaaaatct
    70981 tgctaactgg gctaaaaaag gctcacttat cggggtgaca ggtcgtatcc agactcgtag
    71041 ttacgataac cagcaaggac aacgtgtcta cgtgacagag gtcgtggctg agaatttcca
    71101 aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt ggagcttact ctgcaccaac
    71161 tgcaaactat tcagcaccta caaattcagt accagacttt tcacgtaatg aaaatccatt
    71221 tggagcaaca aacccattgg atatttcaga tgatgattta ccattctaat ggacaactaa
    71281 acttataaag gagaaaaaac atggctcaac aacgtcgtgg cggattcaaa cgccgtaaaa
    71341 aagttgatta catcgcagca aacaaaattg aatatgttga ttacaaagat actgagcttc
    71401 ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg tcgtgtaaca ggaacttcag
    71461 ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc tcgcgtaatg gctttgatgc
    71521 ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc tctttttcat gagcttgaaa
    71581 acaagaaagc gaattaagac cccaatgggt cttttttcac aaactttgaa atgagagagc
    71641 gagttaggct cagtggctcc ctttttacga gtttgaaaac aagagaacac attaaaagca
    71701 cgatggagct ttttcataaa tatgtctttt ttctcatcca agaaattaaa ataaaaatga
    71761 taaacttttt gaaaataggg gatttgccta ctttatgata taatggaaag agttagattg
    71821 aaagaggtag tgagatggac gcgaaattaa gatacaaggc aaagaagatc aagattgtct
    71881 tttttgatat tgatgataca ttgcggaatt caaagacagg gtttattcca actacaattc
    71941 ccactgtttt taaacagttg cgtgaaaaag gaattttaac aggaatcgcc tctggacgtg
    72001 gcatttttgg tgttgttcca gagattcgtg atctcaagcc tgactttttt gtaactttga
    72061 atggggctta tatcgaagat aaaaaaggtc aggtcattta tcagcatcag attgaaaagt
    72121 cagatgttga ggagtatatc tcttgggcta agcaagaagg aattgagtat ggcttggttg
    72181 ggagtcatga tgccaagttg tcgattcgca ccgatatgat gagtgaagct atcaatccaa
    72241 tttatcccga cttagatgta gatcccgatt tccatgaaaa agaagatatc tatcagatgt
    72301 ggacttttga agataaggga gatgacttgc acttgcctga cagtctctca gacaaacttc
    72361 gcatggttcg ttggcatcaa cattcgtctg atattgtgcc gatttcaggc tccaaagcga
    72421 cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc agagaaggtc atggtttttg
    72481 gagatggtct caacgacttg gaactctttg attatgctgg aatcagcgtt gccatgggaa
    72541 tttctcatga taaaatcaaa gaaaaagcag attatattac aaaaacatta gaagaagatg
    72601 gcatttttga tgccttagaa gtatttggta tggtagaaaa agaattgcat tttccacaag
    72661 tagacattga aacagtagaa ggtcctcttg cgactattaa gaccaatcac ggagacttac
    72721 gtatcaagct tttccctgaa catgctccta aaacagtggc taactttgta tctctttcaa
    72781 aagatggcta ctatgatggt gtcattttcc accgtattat caaggacttt atgatccaag
    72841 gtggagaccc aactggaact ggtatgggtg gcgagtcaat ctacggcgaa tcttttgagg
    72901 atgaattctc agaagagctt tacaatatcc gtggtgctct ttccatggca aatgctggtc
    72961 caaataccaa cggcagccag ttctttatcg tgcaaaacca acacctacct tattctaaga
    73021 aagaaattac tcgtggtggt tggccagaac cgattgcaga aatctatgcc aatcaaggtg
    73081 ggacacctca cctagaccgc cgtcacacgg tttttggtca gttagctgat gaagcatctt
    73141 acgctgtctt ggatgccatt gctgctgttg agacaggagc tatggacaag ccagttgaag
    73201 atgttgtaat tgaaactatt gaaatcgagg actaagatga aaatcggtga taagctaaag
    73261 gggcgtatta cagggattca gccctacggt gcctttgttg agttagagac gggtgatacg
    73321 gggctgattc acatttcaga gattcggaca ggatttattg aaaatattca tgaaaccttg
    73381 aaagtcgatg aagaggttca agttcaggta gtggatttag atgaatttac ggggaaagcc
    73441 agtctttcta tccgcacttt ggaggaaaaa aagtaccagt ttcctagacg gagacgcttt
    73501 tcaagcgacc gctttaacta cggttttgct ccctttcgac gaatgctacc aatctggact
    73561 ggagaagccc tgcaccattt aaaaaagaag aagtagttta gagttttata ttttttgtaa
    73621 tgttaatatg aatttgctat aataggacca tggaagaaga acaattatta aaatcaggag
    73681 agcgcattaa ccagctcttt tcgacagata tcaaaatcat tcaaaataga gaggttttta
    73741 gctattcggt ggatagtgtt ctcttatcac gatttccacg ttttcctaag aaggggttga
    73801 ttgtggattt ctgtgctggg aatggagcag tggggctttt tgctagcact cgtactcaag
    73861 cacagatatt gtctgttgag attcaggagc gtttggcgga tatggctgaa cgctctgtcc
    73921 gtttgaatgg attagaggag caaatgcagg tcatctgcga tgatttgaaa aatatgcctg
    73981 ctcacattca ggggagtaag gtggatatga ttttgtgtaa tccaccctat ttcaaggtgg
    74041 atccttattc taatctgaac gagagtgaac attatctctt ggctcgacac gaaatcacga
    74101 ctaatttgga agaaatctgt cgtagtgccc agagtattct caagtctaat gggcgtttgg
    74161 ccatggttca tcgtcctgat cgacttctgg atattttgga tacgttaaaa cgacataatc
    74221 tagcccctaa gcgcctgcag tttgtttatc caaaaagaga aaaggaagcc aatatgcttt
    74281 tgattgaggc gatcaaggat ggctcaacaa gtggctttaa ggtcttacct cctttgattg
    74341 tccacaatga tgatggctct tatacgcccg aaatcgaaga gatttattat ggatcataag
    74401 gcttatatgt acgttctgga gtgtcgtgat ggatcctact atataggcta tacgactgat
    74461 atgagaagac gcctcgctat ccacaatagt gggaagggag ccaaatatac acgagcacgc
    74521 ttgccagtca aacttatcta tgctcaaggt tttgccagta aggaagaagc catgtcggct
    74581 gaagctcttc tcaagcgtaa gaagaggcca cagaaggaag aatttttatc tgaaaatcaa
    74641 gatagaaatt tactcagtta ttttgaagaa tcgtggggag tcctttgact cctcttacct
    74701 ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa acaaaatgag gtattatcat
    74761 gtccaagatt ctagtatttg gtcaccaaaa tccagactca gatgccatcg ggtcatctgt
    74821 agcttttgcc taccttgcaa aagaagctta cggtttggat acggaagctg ttgcccttgg
    74881 aactccaaat gaagaaacag cctttgtctt gaactatttt ggtgtggaag caccacgtat
    74941 tatcacttct gccaaagcag agggggcaga gcaagttatc ttgactgacc acaatgaatt
    75001 ccaacaatct gtatcagata tcgctgaagt agaagtttat ggtgttgtag accaccaccg
    75061 tgtggctaac tttgaaactg caagcccact ttacatgcgt ttggagccag ttggatcagc
    75121 gtcttcaatc gtttaccgta tgttcaaaga acatggtgta gctgtgccta aagagattgc
    75181 aggtttgatg ctttcaggtt tgatttcaga tacccttctt ttgaaatcac caacaacaca
    75241 cccaacagat aaaatcattg ctcctgaatt ggctgaattg gctggtgtga acttggaaga
    75301 atatggttta gcaatgttga aagctggtac caacttggct agcaaatctg ctgaagaatt
    75361 gattgacatc gatgctaaga cttttgaact caacggaaat aatgtccgtg ttgcccaagt
    75421 gaacacagtt gacatcgctg aagttttgga acgccaagca gaaattgaag ctgcaatgca
    75481 agctgccaac gaatcaaacg gctactctga ctttgtcttg atgattacag atatcgtcaa
    75541 ctcaaactca gaaatcttgg ctcttggtgc caatatggac aaggtcgaag cggctttcaa
    75601 cttcaaactt gaaaacaatc atgccttcct tgctggtgcc gtttcacgta agaaacaagt
    75661 ggtacctcaa ttgactgaaa gctttaatgc gtaagatttt gggtgtcagc tcaaaatcgg
    75721 aaagtctagt ttgccttata tcgaaaggag tttcggctcc ttttttctag gagtgaagta
    75781 tgttagaaaa tggcgatttg atttttgtga gagatgggtc agacatggga caggccatcc
    75841 agacttccac aggtaactat agccatgttg ccatttattt ggatgggatg atttatcatg
    75901 ctagtggaca ggctggtgtt gtctgtcaag aaccggcaga cttctttgag tccaatcatt
    75961 tatacgacct ctatgtttac ccagaaatgg atatccagtc ggtgaaggaa agagcttgca
    76021 aacatcttgg agcaccctac aatgcttctt tctatccaga tgcagctggt ttctactgct
    76081 cccagtatat agcagaaatc ctacctattt ttgaaactat tcctatgaaa tttggagatg
    76141 gggagcagga gattagtgat ttttggaggg agtattacat agaactaggt ctgcctgttc
    76201 ctctgaacca agctggtacc aatcctagtc agttggcagc atcgcctctg ttacaatgta
    76261 aagaaaggga tcttcatgat tcagattttt aatccatctc gtttgacgag acagccattt
    76321 ttggagaatt gatccgctat ctggaccagt atgaggatgt gattctacgg gaaattaagg
    76381 ctcaatttcc agatgttgca gttgataaac tcatggaaga gtatataaag gcaggcttga
    76441 ttctacgtga aaataagcgc tattacctca attttcctac gcttgaatca cttgatagtc
    76501 ttgaactgga tcaagagatt tttgtcagag aagctagtcc ggtctatcaa gccttgttgg
    76561 agcagagttt tgagacggaa ttgcgcaatc aaatcaatgc agctatttta gttgaaaaga
    76621 cggactttgc gcgcattaaa atgaccctgt ccaattattt ttacaaggtc aaacagcagt
    76681 atcctttgac agaaaaacag caggagctct atgacatttt aggagatgtt aatcctgagt
    76741 atgccctcaa gtatatgacg gcttttttgt tgaaatttct caaaaaagac cagcttatgc
    76801 agaaatgccg tgatatcttt gtggacagtt tggttgtctt aggctatatt gtgcaaaatg
    76861 aagatagaaa gtatgagttg gctatcgatt ttgataagga gagattaact ttctacttag
    76921 cgtgatttct tgtttctgag cacattgttt gactttcctt agtattcggt ataaactata
    76981 tgtaaccggt aacacatatc ggaataaact aaaggagaca atcatatgtc acttgaaaac
    77041 aaattggaac aagcaacagg cgctgtcaaa gaaggttttg gtaaagttac tggagacagc
    77101 aagacagaac ttgaaggagc tgttgaaaaa acagttgcta aggcaaaaga cgttgtagaa
    77161 gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga aaaacgtttt tactaaataa
    77221 taggaaaaaa tcaagggttt cattttccct tgattttttc tattcttata aataattttc
    77281 tgcgacggct gtatctcctg ggtaggattc tttcttgccc tggatgattt ggtaacaatc
    77341 gactccctta cccgcaataa taactgcatc taattcgtga tttgtgatag ccattgccgc
    77401 cttgatggct tcttggcgat ccgcaatctt ttcaacagga tgattgatgt agctactaat
    77461 ttcatctgca atggccattg ggtcttcata gttagggtca tcagcagtca gaaagacttg
    77521 aatctcaggg tgttgattga ggaggaggcc aaagtcctta cgacgacttt ctcccttgtt
    77581 tcctgttgat cccagaacca gagcaatctt tccggtttga tgagtttcaa ccacattgat
    77641 gagttttttc agactatccc cattgtgggc atagtcgatg aagaccttgg ctccattttt
    77701 ctgagtgagg acttccatac gaccaggaac gcgggttgca gcgatgcctt ttttgatgtc
    77761 ctcaagactt gctccgagac ggagacaagc aagtccagca gcaactgcat tttcttggtt
    77821 gaagttgcca atgagttgaa tatcataatc tccagcgagt ttacccgtag ctgaaaagct
    77881 aaaggctttg gaattctcga tttggttatc aaattggcta ccatagaaat catggtcttg
    77941 atcttcaacc tgttctttca agactgagaa gtggtccatg tcactgttaa tgatgactgc
    78001 tcggctcttt tccatcaaga gacgcttgtg gtagaaatag tcttcaaagc tagggtgttc
    78061 aatcgggccg atatggtctg ggctgatatt taggaaaact cccacatcaa aggttagacc
    78121 atagacacgt ttgaccagat aggcttgact ggagacttcc atgatgaggt gggtacggtc
    78181 attttgcaca gcctgattca tcatgtcaaa gaggtcaata ctctcagggg ttgtcaacgc
    78241 tgacttaaag aaagtctcgc catcaagagt tgtgttcatg gtcgacaaca tagcaggtct
    78301 atgcccttga gataagatgt tataggcgaa ataggctgct gttgtcttac ccttagtacc
    78361 agtaaaggca aggagtttga gtttttcctg tggattacca tagaactcca tggcaatcaa
    78421 actcatggct ttctttatat cgttcacaat gatgacaggg ataccgactt cgtagtcctt
    78481 ttcagctaca taccaagcta atccttgtgt tatagcagaa agaaggtatt cttttttaaa
    78541 ggcagcgcct tttgcgaaaa aaagagtgtc ttctgttact tttcggctgt cgtagctgat
    78601 gctatcaaaa ataactttgc tgtagttgta gtggtaatga ccttggtcaa taatttcgcg
    78661 aaaaaggcca tctttcttta aaatatctaa tacggtttca atcttaatca tactttctat
    78721 tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa gtttataatg gaagataagg
    78781 agtttttcct agctatcaaa attgaatgag gaatctatgt cgcacgaaaa caatcaccag
    78841 caggcccaga tgttacgggg gactgcttgg ctaacggcta gtaactttat cagtcgccta
    78901 ctcggggctg tttacattat cccttggtac atctggatgg gggcttatgc agctaaggca
    78961 aatggtctct ttaccatggg ttacaatatc tatgcttggt tcttgttggt ttcaacagcg
    79021 gggattccag ttgcggtggc caagcaagtt gccaagtata ataccatgcg agaagaagag
    79081 catagctttg ccctgattcg gagtttctta ggctttatga caggactagg cctggttttt
    79141 gctttagtct tgtatgtctt tgctccttgg ctagcagact tgtctggcgt gggcaaagac
    79201 ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga ttttcccgtc tatgagtgtt
    79261 atccgaggat ttttccaagg gatgaataac ctcaaaccct atgccatgag ccaaattgct
    79321 gagcaggtca ttcgtgttat ctggatgctc ctagcaacct ttatcattat gaagctcggt
    79381 tcaggagatt atctagcagc cgttacccaa tcaacctttg ctgcctttgt cggtatggta
    79441 gccagttttg cagtcttgat ttatttcctt gcccaagaag gttcactcaa aagagtcttt
    79501 gaaacaggag ataagattaa cagtaagcgt ctcttggttg ataccattaa ggaagccatt
    79561 ccttttatcc tgacagggtc tgccatccag ctcttccaga ttttggatca gctgaccttt
    79621 atcaatagta tgagctggtt taccaactac agcaatgagg acttggttgt catgttttct
    79681 tatttctcag ccaatcctaa taaaatcacg atgattttga tttctgtagg ggtttcgatt
    79741 gggagtgttg gtttgccact tttgacggaa aactatgtca agggggactt gaaagcagct
    79801 tctcgtctcg ttcaggacag tctcacccta ctctttatgt tcttgctacc agcaacggtt
    79861 ggagtggtta tggtaggaga acctctatat acagtcttct atggtaagcc agatagtttg
    79921 gctctgggct tatttgtctt tgcagttttg cagtctatta ttttaggctt gtacatggtc
    79981 ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg ccgttctcta ttttatctat
    80041 ggttctattg ccaagctagt cttgcaacta cctaccatcg ccctcttcca cagttatggt
    80101 cctttgattt caacaaccat tgctctcatc attcctaacg tcttgatgta tcgggatatt
    80161 tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc gaactatttt aatcagtttg
    80221 ctgaccctag tcatgtttct gttaatagga accatccagt ggctgttagg atttttcttc
    80281 caaccaagtg gacgtttgtg gagcttcttt tatgtagctc ttgtcggtgc catggggggt
    80341 ggactttata tggttatgag tctgcgtacc tatttattag ataaggtaat aggaaaagcc
    80401 caagcagatc gcctgcgagc aaaatttaag ctttcgtaag gtagcattta taaataaaag
    80461 gaataagttg aacaatcttt taggagaact tgaaacttat tcctttttta gcgtaaaaat
    80521 agctaaaatt atctttcaaa aatagaaaat gaggtttttt tgattttttg gaaaaaacaa
    80581 ttgactaaac aaaccaagag ttgtataata aaacaaatat ttaaagcagg aggttccgga
    80641 aatgaaaaag tctaagagca aatatctaac cttggcaggt cttgtcctgg gtacaggagt
    80701 tttattgagc gcgtgtggaa attctagcac ggcgtcaaaa acctacaact atgtttattc
    80761 aagtgatcca tctagcttga actatctagc agaaaaccgc gcagcaacat ccgatattgt
    80821 tgcaaatttg gtagacgggt tattagaaaa tgaccaatat gggaatatta ttccatcatt
    80881 agcagaggat tggactgttt ctcaggacgg tttgacctat acctacaaac ttcgtaagga
    80941 tgccaagtgg tttacttctg agggagaaga atatgcgcct gtaactgccc aggattttgt
    81001 gacaggtttg caatatgcag ctgataaaaa atcagaagcc ttgtatctag tgcaggactc
    81061 tgttgctggt ttggatgact atatcactgg taaaacaagc gacttttcaa ctgtcggtgt
    81121 caaggcactt gatgaccaaa cggttcaata tactttggtt aaaccagaac tttactggaa
    81181 ttcaaaaaca cttgcaacga tactttttcc tgttaatgca gatttcctga aatcaaaagg
    81241 ggatgatttt gggaaggcgg atccatctag tattttgtac aatggacctt tcttgatgaa
    81301 agcacttgtc tcaaaatctg ctattgaata taagaaaaac cctaattact gggatgctaa
    81361 gaatgtcttt gtagacgatg tgaaattgac ctactatgat ggtagcgacc aagaatcact
    81421 ggaacgtaat tttacagctg gtgcttatac tacggctcgt ctttttccta acagctccag
    81481 ctatgaaggg attaaagaaa aatacaaaaa caatatcatc tatagtatgc aaaattcaac
    81541 ttcatatttc tttaatttta acctagatag gaagtcttac aattatactt ctaaaacaag
    81601 tgacattgaa aagaaatcga ctcaggaagc agttctcaat aaaaacttcc gtcaggctat
    81661 caattttgct tttgacagaa catcttatgg ggctcagtct gaagggaaag aaggtgcaac
    81721 aaagattttg cgtaacctag tggttcctcc aaactttgtc agtatcaagg gaaaagactt
    81781 tggtgaagtt gtagcctcta agatggtcaa ctatggtaag gaatggcaag gtatcaactt
    81841 tgcggatggt caagaccctt actacaatcc tgagaaagcc aaggctaagt ttgcggaagc
    81901 taagaaagaa ctcgaagcaa agggtgttca attcccaatc cacttggata agactgtgga
    81961 agtaacagat aaagtaggca tacaaggagt tagttctatc aaacaatcaa ttgaatctgt
    82021 tttaggttct gataatgtag tgattgacat tcagcaatta acatcagatg agtttgacag
    82081 ttcaggctac tttgctcaaa cagctgctca gaaagactat gatttatatc atggcggttg
    82141 gggacctgat tatcaagacc cgtcaaccta tctcgatatt tttaatacta atagtggagg
    82201 agttctacaa aatcttggac tagagcctgg agaagccaat gacaaggcta aggcagttgg
    82261 actggatgtc tatactcaaa tgttggaaga agctaataaa gagcaagatc cagccaaacg
    82321 ttatgagaaa tatgctgata ttcaagcttg gttgattgat agttctttag ttcttccaag
    82381 tgtttcgcgt gggggaacac catcattgag aagaaccgta ccatttgctg ctgcctatgg
    82441 tttaaccggt acaaaagggg ttgaatcata taaatacctc aaagtacaag ataagattgt
    82501 cacaacagac gaatatgcaa aagccagaga aaaatggttg aaagaaaaag aagaatccaa
    82561 taaaaaagcc caagaagaat tggcaaaaca tgtcaaataa aatctaattg tagataagtt
    82621 tgtgtaagaa gtctttgtgc ttaaaaacgc ataatatcag gtatataaaa tcctagatgt
    82681 tatgcgtttt gttataggaa gatttattag attttatcct caaattgagt tattctcgac
    82741 tttatccgtt gaaatattat aaggagtatt tatgaaatta aaattattaa gagtagatac
    82801 taaggtgatt atggggagtt tcttacttgt tctgtctagt ctacttgctt tgttgcttcc
    82861 ccttatctta aagggtttaa tagatgggag ttctattgaa aatataggtt ccaaagtatt
    82921 tcaatcgttt ttgattttta ttggtcaagc cttgttttct tctattggtt actatctgtt
    82981 tagtcaatcg ggtgaaaaaa agatagcaaa aatcaggaaa aaagtgatag aggggttgat
    83041 ttatgcagag aaatccttct ttgataagag ccaaagtggg gagttgactt ctgccattgt
    83101 caatgacacg agtgtcattc gtgagttttt aattacgact ttcccaaata ttattctgag
    83161 tttagttatg gtacttggtt ccattgtagt cttatttagt cttgattgga atctttctct
    83221 acttttattc atcactcttc cttgtatgat gtttattatc ttgccccttt ccaatatcag
    83281 tgaaaagtat agtcgtcgtt tacaggagga aatcggattt ttaacagggc aattgactga
    83341 aaagattcaa gaacatgaat taattaagac taaccaagca gagaaaagtg tacaggatgt
    83401 tttggataat tgtattgaaa gggtacaaaa caattcactg aaatcagata gggttacttc
    83461 ttttgagacc ccgtttgctc tcttatttat ctttgcgact atagttgtga tgctaaccta
    83521 tgggggttat cgggtcagcg caggatatat atctgtggga accttggttt cgtttttgat
    83581 ttacctcttt caattactta atcctattag taatatagct aattttgtaa ctatttattc
    83641 taggagcaag ggatcttcag ttgcactgga gaacttgctt gcagttccta aagaaaaatt
    83701 tgagtgagga aaatcggtat caggacaagg gttgaatttt aaccatgtct attttggtta
    83761 tgatgaaaat cgacctgtct taaaggatat tacttgttca attttcaagg ggcaaaaaat
    83821 tgcttttgtt ggaccatctg gatcaggaaa atcaacgatt gtgcgtttgt tagagcggtt
    83881 ttataaaccg ctttcaggat atattctaat ggagcaatca agtatatatg attttaactt
    83941 aaaagaatgg agaagtaaaa tcgcttgggt ttcacaaaat aatgcagtct tatctggcag
    84001 tattcgtgac aatctttgtc tcggtttgaa tcgcttagta actgatgatg aattgatgaa
    84061 agtgctagac ttagtatcac taggtgatga gattcgctcc atgaaagagg gactagatac
    84121 tgaagttggt gaacgcggac gattcttgtc aggggggcaa agccaaagac ttcaaatagc
    84181 tagaacctac ttaaaagatg ctgaaattct tatatttgat gaatccactg ctaatcttga
    84241 tgcggattct gagtatgcga ttatcagtat cctctattct gcattaaagg agaagacggt
    84301 tgtgattata gcgcatcgtt tgtcaacggt aaaagatgtg gattgtattt tcttcttaga
    84361 gggggggaaa atcactggct caggaactca taaggaacta ctggaaaatc atgagcgtta
    84421 tgctcgtttt gtgcaggagc aaatgataga gtgaaggtgt cttttgagat tcaccatttt
    84481 atagtctatt aaagggagca ggaaaaactc cctttttata tagtttgaaa ctataactag
    84541 ctcttgaaaa gaagaaaatg agttgatgaa aataagtggt acaatagtta ctatagattt
    84601 ggaggtattg tatgagcaag gaattacaca ttaacacaat tttggctcag gcgggtatta
    84661 agtcagatga agcgacaggt gcattggtga caccgcttca tttttcaacg acctatcagc
    84721 atccagagtt tggtcgatct actgggtttg actatacgcg cactaaaaat ccaactcgta
    84781 gtaaggctga ggaagtcttg gcggctattg agtcagcaga ctatgcccta gcgactagct
    84841 cagggatgtc agctattgta ctggccttta gcggctttcc agtaggaagt aaggtcttgg
    84901 cagtgcgtga tctttacggt ggttcttttc gctggtttaa ccaagtggag caggaaggtc
    84961 gtttccattt tacctatgcc aatacagaag aagagttgat tgctgagtta gaaaaggatg
    85021 tggatgttct ctatatcgaa accccaacca atcccttgat gttggaattt gatatcgaaa
    85081 aactagcaaa attggctcat gctaagggtg ccaaagtggt ggtggacaat accttctata
    85141 gccctatcta ccaacgtccg attgaagatg gagcagatat cgttctccat tcagcaacca
    85201 agtatctagc aggccacaat gatgtcttgg ctggagtggt tgtgaccaat agtttagaac
    85261 tatacgagaa gcttttttac aatctcaata caacaggggc agtcttgtct ccatttgaca
    85321 gctaccagtt gcttcgtggt ctcaagacct tgtctcttcg tatggagcgc tcaacagcta
    85381 acgcccaaga agtggttgcc tttttgaagg attctccagc agttaaggaa gttctctaca
    85441 ctggtcgtgg aggcatgatt tcctttaaag tagccgatga aacacgcatt cctcatattt
    85501 tgaacagtct caaggtcttc tcttttgcgg aaagtttggg cggagtggaa agtcttatta
    85561 cttatccaac gactcaaact catgctgata ttccagcaga agtacgccat tcttatggtt
    85621 tgacagatga cctcttgcgt ttgtctattg ggattgagga tactagagat ttgattgcag
    85681 atttgcgcca agccttagaa ggataagaca aagatgggaa aatatgattt tacaagcctg
    85741 cccaaccgtt tagggcacca tacctataaa tggaaagaaa cagaaacgga tagtgaagtt
    85801 ctaccagctt ggatagcgga tatggacttt gtggtcttgc ctgaaatccg ccaagccgtg
    85861 caaacttacg cagaccaact ggtttatggt tatacctatg ccagtgaaga cttaattaag
    85921 gaagttcaaa agtgggaagc tacacaatac ggttacaact ttgacaaaga ggctcttgtc
    85981 tttatcgagg gtgtggtacc agccatctca acagctattc aaacctttac aaaagaaggc
    86041 gaggcggttt taattaacac gcctgtctac ccaccctttg ctcgcagtgt caagttgaat
    86101 aatcgtagat tgattactaa ttccttagtg gaaaaggatg gtctgtttga gattgacttt
    86161 gaccaacttg aaaaggattt ggtggaagag gaggttaaac tctatattct ttgcaatcct
    86221 cacaatcctg gtggacgtgt ttgggaaaaa gaagtgttgg agaagattgg ccaactctgc
    86281 caaaaacacg gtgttttgtt agtttcggat gagattcacc aagatttgac cctctttggt
    86341 cacaaacacc agtctttcaa taccatcaat cctgccttca aaaattttgc tatcgtcttg
    86401 agcagtgcca ctaaaacatt taatattgct ggaacaaaaa attcctatgc agtcattgaa
    86461 aatcctaagt tgagactggc tttccagaaa cgcctgttgg ccaataatca gcatgaaatt
    86521 tcaggcttgg gttatttggc gacagaagct gcctatcgat acggtaaaga ttggctagag
    86581 gaactcaagc aagtctttga agaccacatc aattatgtgg tagatctatt tggaaaagag
    86641 actaaaatca aggtcatgaa accgcaaggt acctacttga tttggcttga cttttcagcc
    86701 tatgacctga ctgatgaaac attgcaagag ttgttgagaa atgaagccaa ggttatcctc
    86761 aaccgtggtt tggattttgg agaggaagga agtctccatg cccgcatcaa tatagctatg
    86821 cccaaatctc tgttgcagga agtctgtcag cggattgtgg ttacttttgc caaacgttaa
    86881 aaatccagtc ttctaggaga aaagtcttcc tagaaggcta ttttcatagg cgaaaatatg
    86941 gtataataaa aagataaggt aaaggtgaaa atatggctaa attgattccg gggaaagttc
    87001 gtatcgaagg tgttgccctt tatgaaactg gtaaggttga tatcatcaag gaaaagaaca
    87061 atcggctcta cgctcgcgtt gcagaagaag aactgcgcta tagtttagag gatgatttgg
    87121 ttttttgtgc ctgtgattct tttcaaaaga ggggctactg tgtgcatttg gcagcgctag
    87181 agcattttct gaaaaatgat gagcgtggtc aggaaatctt gtggagtctg gaagaaggtc
    87241 atgaagaaaa agaggccgtt gaaaccaagg tgaccttggg tggcaagttt ttgaatcgaa
    87301 ttttatctcc aaaatcagaa tgcgcctatg agttatcagc tgtgggtcag gtggaagcag
    87361 gaaccaatca tatcttgtgg actctgagaa tcggccaaat caatagccaa aaatactatg
    87421 tcattcggga tattccactt tttttaagga ttgtcgagca gagaaagtcg tatatgattg
    87481 gcaagattta tgaggagtct ctttcttggg aagcctttga tgatgccagc caagaacttt
    87541 tgactttctt gcacggacta acggaggaag ggctggttcc agacctcttt ttccaaaacc
    87601 aaggtcggca cctctttttc cctctgacct tttttgagca gggtgtgaat ttactgatgg
    87661 ccttgcccca ttttcaattt gaccatcaag tggatagcta ccaaaccctg ctttttcagg
    87721 atatgcatgc tgatgccaat ctatttgcct ttacagtaac agaatactcg gactattttg
    87781 aaatggaaat cagtgagagt cctagggtca atgtctttta tcaaggagca gtacttttcc
    87841 ataaaggtca ggtttatttt ttaacagacc agcagatgcg tcttctcaag gaaattaaag
    87901 cgttacctgt gggtcaacaa ggaaagaaat acctgcaatt tgatagcagt gatcgagaca
    87961 aattggcctc ctgtctgact ctttttatcc agatgggcac cgtttcagct ccagaacgtc
    88021 tacaaatcaa aacttttgcg ccctcttttt actttgacag ggaagaagat aatcggattc
    88081 gtttagaaat tcagtttgat tatggaaata gacaggtatc tagccgacaa gagctagaag
    88141 aattaccctt ttcaagtgac gcggacttag aagaaagaat tttccaagtc tgtttggctg
    88201 cgggctttga agccgatttt caatcttggc gtcaggcctt aaaagcggag tctgtctatc
    88261 atttttttca tgatatcatt ccagtctttg aaaaactcgg gcatgttgac ctatcagata
    88321 aactagaaga gctttatagc ctagcgagtc ctcaggtgca gattgcctcc aagggaggtc
    88381 tcttggaaat ccagtttgat tttcaaaata ttgcccagga ggaaatcgac caagccatgc
    88441 aggccttggt tgccaatcag gatttttata ttgattcgtc taatcaagtt tactttttcg
    88501 atgaagaaac caagaaaatt cgccaaaatc tccaggaact ggggcaattt gaattaaaag
    88561 atggaacctt gcaggctcgg aaatccttgg cctacagttt agctcatctc tttgaagggc
    88621 gagaccgtgt ttctttttca caagaattcc agaatctggc ccaggatttg acgcatccag
    88681 aggactttcc tttgcaagca actcaggtca aggctgactt gcgagattat caggaaaagg
    88741 gaattggctg gttgcagatg ctccatcatt atggttttgg tgggattttg gctgatgata
    88801 tgggacttgg gaaaaccctt cagaccattg cttttttgac tagtcaagtg acaaaagaaa
    88861 gtcgagtctt gattctcgct ccgtcaggtt tgatttacaa ctgggcagat gagtttcaga
    88921 aatttgcccc acagttggat gtggttgttg ttcatggttt gaaagcaagt cgtgaggaga
    88981 ttcttgccga gagccatcaa atctatgtga ctagctatgc caccttccgt caggacagtg
    89041 agttttatca ggggatggcc tttgacttcc ttttcttaga tgaggctcag gtcatgaaaa
    89101 atgcccagac caagattgcc cagaccttga gacaatttgt ggtgccgtcg gtctttgcct
    89161 tgtcaggaac tccgattgaa aaccatctgg gtgagttgtg gtctattttc caaatcgtca
    89221 tgcccggact tttgccaagc aagaaagaat ttatgaaatt gccagcagag cgagtggctc
    89281 agtttatcaa gcctttcgtg atgcgacgca agaaagaaga agttctgact gaattgccag
    89341 acttgattga ggtggtttat aaaaatgaac tggaagacca gcaaaaggct atttaccttg
    89401 cccagttaca acagatgcga gaccatctgg ctcaagtgtc agaacaggaa tttcagcgaa
    89461 gtcgtgtgga aattttatct ggtttgatgc gcttgcgtca aatatgtgac actcctgccc
    89521 tgtttatgga agattatcag ggagccagcg gcaaactaga tagtctccga gacctactgg
    89581 tacaggtggc agacggcgga caccgtgtct tgattttctc tcagttcaag ggaatgttgg
    89641 aaaaaattga acaagaactg ccagacttgg gcctgacttc ctttaaaatt acgggttcaa
    89701 ccccagccaa ggaaagacaa gacatgacca aggcctttaa tcaaggagaa agagatgcct
    89761 ttctgatttc cctcaaggct ggtggggtcg gtctgaacct gacaggtgca gatacagtga
    89821 tcttggttga cctttggtgg aatcctgcgg tggaagcgca agccattggc cgtgcccatc
    89881 ggatgggtca ggaagaaacg gttgaggtct atcgcttggt gaccaaggga accattgaag
    89941 aaaaaattca ggaactccaa gaacaaaaga aacatctggt gtcacaagta ttggacggca
    90001 cagagtcacg tggtagtctg accctagcag aaattagaga aattttggga atttctgaag
    90061 ccagcacttg aaaaatcaag acaatacgct ataatgaagt gttgaaagga aatagaaaat
    90121 gaaacaagaa cgatttccat tggtgtcaga tgacgaggtc atgttgactg aaatgccagt
    90181 catgaatctc tatgatgagt ctgatctgat cagtaatatc aagggtgagt atcgagataa
    90241 aaattattta gaatgggctc ctattgctga agaaaaacca gtacaaccga ttgaaaagca
    90301 agtagggaaa cctaaaaaag ctcctttagg ggttaaaaaa gaaggaaaga gctatgcgga
    90361 ggtggcgcgt gaagaagcgc gtgcagactt gaaaaagaaa cgctctgcta actatctaac
    90421 tcaggatttc agccttgcga gacgtcattc tcagcccagt ctagttagac agggcaatca
    90481 accgacaact cctttccaaa aggaaaatcc tggtgaattt gtcaaatata gccaaaaatt
    90541 gacccagtct cattatatct tggcggaaga agttcattct atccctacca agaatgaaga
    90601 agtgtcagca cctgctccaa agaaaaacaa ttatgatttt ctaaagaaga gccaaatcta
    90661 caataaaaaa agtaaacaaa cagaacaaga acgtcgggtt gcccaagagt tgaatctgac
    90721 cagaatgaca gaatagggga gaaaacatgt caaagacata tcattttatc ggaattaagg
    90781 gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag gttcagggat
    90841 cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga attaccattc
    90901 ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga aatgcctttc
    90961 gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc tacaaacgtt
    91021 accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta gcaggagcac
    91081 atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt acagatacca
    91141 gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat tttgtctttg
    91201 aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct attatcacca
    91261 acattgactt tgaccatcca gattatttca caagtctcga ggatgttttt aatgccttta
    91321 acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat gctgaattgc
    91381 gtaagattac gtctgatgca ccaatttatt attatggttt tgaagttgaa ggcaatgact
    91441 ttgtagctag tgatcttctt cgttcaataa ctggttcaac cttcaccgtt catttccgtg
    91501 gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc atgaatgcga
    91561 cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg cgtgagcact
    91621 tgaaaacatt tgctggtgtt aaacgtcgtt tcactgagaa aattgtcaat gatacagtga
    91681 ttatcgatga ctttgcccac catccaacag aaattattgc gaccttggat gcggctcgtc
    91741 agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt acaagaacca
    91801 ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt tatctagcgc
    91861 aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa gatctagcca
    91921 acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg ctcctagacc
    91981 atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat gaatactcat
    92041 ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc atggaaattc
    92101 caattaagat cattcaggca agcaagtctg atttgcctga gataggggca cttcagacct
    92161 cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt atccgtaagt
    92221 gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat attttatcaa
    92281 gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc gagtctgacc
    92341 atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg gcagttgagc
    92401 tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat tttgaaatga
    92461 acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc tatagtatga
    92521 tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa gattagaaga
    92581 tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag ccattcctcc
    92641 ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg ctgaaaaaga
    92701 aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc tgcaagacca
    92761 gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata tctctgtgac
    92821 ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat tgctgacagc
    92881 cttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct gtcatgacta
    92941 tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc agtcaacctt
    93001 tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta ggaaaagtat
    93061 catagattgc tttttttgga cttttaagat ataatattat ggattatcaa caaggaggaa
    93121 aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga gcagattctg
    93181 agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga ggcagtagtt
    93241 cgcactcctg caaatgaacc ttcagctgaa gaactcatgg ctgattcctt gtcaacggta
    93301 gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg tgtaccagct
    93361 tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc aagtcaagat
    93421 gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtccaggtcc tgttagacct
    93481 aagaaacttg aaagagaata caatgaaacc ccaacaaggg tagctgtttc ctatacgacg
    93541 gcagagaaaa aagcagaaca agcaggttca gaaacaccta cgcctgctac agaaacagtg
    93601 gatatcatca gcgatacatc acgtcgtagc cgtagagaag gagcaaaacc cgttaagcct
    93661 aagaaagaga agaagtcaca tgtgaaagct tttgtgattt cattccttgt attccttgcc
    93721 ttgctctcag caggtggtta ctttggttac cagtacgtgc tagattcttt gttacctatc
    93781 gatgctaatt ctaagaaata tgtgacggtt ggaattccag aaggttcaaa cgttcaagaa
    93841 atcggtacga cgcttgaaaa agctggtttg gtaaagcatg gtctgatttt tagtttttat
    93901 gccaagtata aaaattatac cgacttgaaa gcaggttact acaatttgca aaagagtatg
    93961 agtacagaag acttactcaa agagttgcaa aaaggtggaa cagatgaacc gcaagaacct
    94021 gtacttgcga ctttgacaat tccagaaggt tataccttgg atcagattgc tcaagctgtg
    94081 ggtcaattgc aaggtgactt caaagagtct ttgacagcgg aggctttctt ggctaaagtt
    94141 caagatgaga cgtttatcag tcaagcagta gcgaaatatc ctactttact ggaaagtttg
    94201 cctgtaaaag acagcggtgc gcgttatcgt ttggaaggat accttttccc agctacatac
    94261 tctatcaagg aaagcacaac tattgagagc ttgattgatg agatgttagc tgctatggat
    94321 aagaacctat ctccttacta tagtactatc aaatctaaaa atttgactgt caatgagttg
    94381 ttgaccattg cttccttggt cgaaaaagaa ggtgccaaga cagaagatcg taagctcatt
    94441 gcaggtgtat tctacaatcg tttgaatcgt gatatgccac ttcaaagtaa tattgcaatc
    94501 ttgtatgccc aaggaaaact ggggcaaaat atcagtctag ctgaggatgt tgcgattgat
    94561 accaacattg attcacctta taatgtttat aaaaatgtag gtctcatgcc tggtccagtc
    94621 gatagtccaa gtctggatgc gattgagtca agcatcaatc aaactaagag cgataacctc
    94681 tactttgtag cagatgtcac agaaggcaag gtctactatg ctaacaatca agaagaccac
    94741 gaccgcaatg tcgctgaaca tgtcaacagc aaattaaact aaacaaacta aaattatgtg
    94801 atacttcaca taattttctt tagaaaatat tatcagaaga aagttgagaa aaatggcaga
    94861 aaaaacatat cctatgaccc ttgaggaaaa ggaaaaactt gaaaaagaat tagaagaatt
    94921 gaaattggtt cgtcgaccag aagtggtaga acgcattaag attgcccgtt catacggtga
    94981 cctttcagaa aacagtgagt acgaagcagc taaggatgaa caagcctttg tcgaaggaca
    95041 aatctctagc ttagaaacaa aaatccgcta tgctgaaatc gtcaatagcg acgcagttgc
    95101 ccaggacgaa gtagcgattg gtaaaacagt caccatccaa gaaattggtg aggacgaaga
    95161 agaagtttat attatcgtag gttcagctgg tgcggatgcc tttgcaggta aggtttcaaa
    95221 tgaaagccca attgggcagg ccttgattgg caagaaaaca ggtgatacag caaccattga
    95281 aacgcctgtt ggtagctatg atgtaaaaat cttgaaggtt gaaaaaacag cctaaaaaca
    95341 gaaaaaggag tggggaggcg atgtgcttca ctcactcctt tttccatttt gctactcttc
    95401 gaaaatctct tcaaaccacg tcagcgtcgc cttgccgtat gtatggttac tgacttcgtc
    95461 agtttcctag tttgctcttt gattttcatt gagtattaga tgtataatgc attgaagtta
    95521 aaatagtaca ctttgatttc taagacattg ttagaaatta gattaaattc cttaatcgat
    95581 ttgcgcatgt tttatttcat ttcattatac cttagattgg aaaataagga atcacataaa
    95641 tcgcaagaaa tagggaatct gattcgtgtt tataaccgtt caaaaagaga agaggctgaa
    95701 agtgagccac ttaatcttta tgtcgaagat gaaaagggca atctccttgc gggtttgata
    95761 gcagagactt ttggaaattg gctagaaatc gagtatttgt ttgtaaaaga ggaactgcga
    95821 gggcaaggaa tcggttcaaa actattgcaa caggcagaaa gtgaagctaa gaatcgaaat
    95881 tgttgttttg cctttgtcaa tacttaccag ttccaggcac tggactttta tcagaaacat
    95941 ggctacaagg aagttttttc tttgcaagac tatctctaca ttaggcaaag atattattac
    96001 caaaagaatc tgtaaggcga gtatggaggt ggactgatgt atatgagtaa ctatcgataa
    96061 ataccagtta taacctagaa attgtgtctt tctagacgat attgaggaca atataatcgt
    96121 agccccaaaa ttaggaatca aggcttatca ggttaagaaa agaagtgatg ttgttgatat
    96181 tttaaaacaa tttatttaaa ctaaaaactc tctatctttt taaattgaca ttaatccgag
    96241 attcccctct cggattttgt gttgctttca ttaaatttac aggtaagcct tgctagcttc
    96301 agtaaatata cacaagtttt tcagaataga gtgaaatcca aaagaaaatg gaaataatga
    96361 aagctcttgt aggcataaga aaacacctct gtgttatact tgttgttcaa ccacaaacac
    96421 aagaaaggca cagagatgca aaaccattat actacaaaag gtaaacattt gacaatcgat
    96481 agccgtcgct taatcgaacg atggaaaaaa gaaggaaaat caaatagaga aattgcctct
    96541 ctgcttggaa aagttcctca aactatccac actgaaatca agcgtgggac agtccgacaa
    96601 tgtcttggaa aagggcgctt caaagaggtt tattctgccg actatgctca acagtcttat
    96661 gaaaacaatc gcaagcgctc ggtcaggaaa ttaagcgtga ccaaggaact aaaggaaaag
    96721 attctccact atcataacca aaaattttcg cctgaaatga tggtgatggc taaaggggtt
    96781 aacgtgggaa tttcaaccat ttactattgg attcatcatg gaaaattggg gttaagcaaa
    96841 caggatctgc tttaccctag aaaaggaaaa gcgcttaaga aacaggctag catcaacttt
    96901 aaacctgctg gtcaatccat cgcacagcgg cctgaagcta tcaatcttcg cttggagaat
    96961 gggcattatg agattgatac ggttctactt acgagagcga aaaactactg cttgcttgtc
    97021 ttgacggatc gaaagagtag acatcagatc atccgattga ttccaaataa aagtgctgag
    97081 gtggtcaatc aggctctaaa actcatctta aaacaacaca agattctttc catcacggca
    97141 gataatggaa cggaattcaa tcgcttgttt gatatatttt ctgaggagca catctattat
    97201 gcgcacccct atgcctcttg ggaaagggga actaatgaga atcacaacag gctcattcgt
    97261 agatagttac ctaagggaac caagaaaatg actcccaaag aagtcgcatt catcgaaaag
    97321 tggattaaca actatcctaa aaaatgcttg gactacaagt cacccagaga agacttctgg
    97381 atggctaact tgaacttgaa atttagcaaa atggaaataa tttttattaa acgcttccaa
    97441 tagcggttaa aagttgacaa atttaaattt taggactaca ctaagtaagt aaattttatt
    97501 ttaaaggaga atttgttatg aatttaacat ttttaggctt atgtattgcc tgtatgggcg
    97561 tatctgtcgg tgaaggttta ttgatgaatg gactgtttaa atcagtagca cgccaaccag
    97621 atatgctttc tgagtttcgt agtttgatgt ttttaggtgt tgcctttatt gaaggaactt
    97681 tctttgtaac tcttgtcttc tcatttatta tcaaataaat acatggaacg agaagaaaag
    97741 ggaggatttt agatggaaga aagtattaat ccaatcatct ctattggtcc tgttatcttc
    97801 aatctgacta tgttagccat gactttgttg attgtgggag ttatttttgt ctttatttat
    97861 tgggcaagcc gcaatatgac cttgaaaccc aaaggaaagc aaaatatact tgagtatgtc
    97921 tatgactttg ttattggatt tacagaacct aacattggtt cgcgctacat gaaagattac
    97981 tcactctttt tcctttgttt attccttttc atggtgattg ccaataacct tggcttaatg
    98041 acaaagcttc aaacgatcga tgggactaac tggtggagtt cgccaaccgc taatttacag
    98101 tatgacttaa ccttatcttt tcttgtcatt ttgttgacac atatagaaag cgttcgtcgt
    98161 cgtggattta aaaaaagtat aaaatctttt atgagtcctg tttttgtcat accgatgaat
    98221 atcttggaag aatttacaaa cttcttatct ttggctttgc ggatttttgg gaatatcttt
    98281 gcaggagagg tcatgacgag tttgttactt cttctttccc accaagctat ttattggtat
    98341 ccagtagcct ttggagctaa tttggcttgg actgcatttt ctgtctttat ttcctgcatc
    98401 caagcttatg tttttactct tttgacatct gtgtatttag ggaataagat taatattgaa
    98461 gaggaataga aaggagtaac tgatgcacgt aacagtaggt gaattaattg gtaattttat
    98521 tttaatcact ggctctttta ttcttttgct agtcttgatt aaaaaatttg catggtctaa
    98581 tattacaggc attttcgaag aaagagctga aaaaattgct tcagatattg atagagctga
    98641 agaagcccgt caaaaagcag aagtattggc tcaaaaacgc gaagatgaat tggctggtag
    98701 ccgtaaagaa gctaagacaa tcattgaaaa tgcaaaggaa acagctgagc aaagtaaggc
    98761 taatatctta gcagatgcta aactagaagc aggacactta aaagaaaaag ccaatcaaga
    98821 aattgctcaa aataaagtag aagctttaca gagtgttaag ggtgaggtcg cagatttgac
    98881 catcagctta gctggtaaaa tcatctcaca aaaccttgac agtcatgccc ataaagcact
    98941 cattgatcag tatatcgatc agctaggaga agcttaatgg acaagaaaac agtaaaggta
    99001 attgaaaaat acagcatgcc ttttgtccaa ttggtacttg aaaaaggaga agaagaccgt
    99061 atcttttcag acttgactca aatcaagcaa gttgttgaaa aaacaggtct gccttctttt
    99121 ttaaaacaag tggcagtaga cgagtcggat aaggaaaaaa caattgcttt tttccaagat
    99181 tctgtgtcgc ctttattaca aaactttatc caggttctgg cctacaatca cagagcaaat
    99241 cttttttatg atgtgcttgt agattgcttg aaccgacttg aaaaagaaac aaatcgattt
    99301 gaagtgacga ttacgtctgc tcatcctcta actgatgaac agaagactcg tttgctccct
    99361 ttgattgaga aaaaaatgtc tctgaaagta aggagtgtaa aagaacaaat cgatgaaagt
    99421 ctcattggtg gttttgtcat ttttgccaat cacaagacaa ttgatgtgag tattaaacaa
    99481 caacttaaag ttgttaaaga aaatttgaaa tagaaagtgg tgttcttttg gcaattaacg
    99541 cacaagaaat cagcgcttta attaagcaac aaattgaaaa tttcaaaccc aattttgatg
    99601 tgactgaaac aggtgttgta acctatatcg gggacggtat cgcgcgtgct catggccttg
    99661 aaaatgtcat gagtggagag ttgttgaatt ttgaaaacgg ctcttatggt atggctcaaa
    99721 acttggagtc aacagacgtt ggtattatca tcctaggtga ctttacagat atccgtgaag
    99781 gcgatacaat ccgccgtaca gggaaaatca tggaagtccc tgtaggtgaa agtctgattg
    99841 gtcgtgttgt ggatccgctt ggtcgtccag ttgacggtct tggagaaatc cacactgata
    99901 aaactcgtcc agtagaagca ccagctcctg gtgttatgca acgtaagtct gtttcagaac
    99961 cattgcaaac tggtttgaaa gctattgacg cccttgtacc gattggtcgt ggtcaacgtg
   100021 agttgattat cggtgaccgt cagacaggga aaacaaccat tgcgattgat acaatcttga
   100081 accaaaaaga tcaagatatg atctgtatct acgtcgcgat tggacaaaaa gaatcaacag
   100141 ttcgtacgca agtagaaaca cttcgtcagt acggtgcctt ggactacaca atcgttgtga
   100201 cagcctctgc ttcacaacca tctccattgc tcttcctagc tccttatact ggggttgcta
   100261 tggcggaaga atttatgtat caaggtaagc atgttttgat tgtatacgat gatctatcaa
   100321 aacaagcggt agcttatcgt gaactatcgc tcttgcttcg tcgtcctcca ggtcgtgaag
   100381 ccttcccagg ggatgttttc tatctccaca gccgtttgct tgagcgctca gctaaagttt
   100441 ctgatgaact tggtggtgga tcaattacag ccctaccatt tatcgagaca caagcaggag
   100501 atatctcagc ctatatcgca accaacgtga tttctatcac tgatggacaa atcttccttg
   100561 gcgatggcct cttcaatgca ggtattcgtc cagccatcga tgcgggttca tctgtatctc
   100621 gtgtaggtgg ttctgcacaa atcaaagcca tgaagaaggt tgctggtaca cttcgtatcg
   100681 accttgcttc ataccgtgag ttggaagcct ttactaagtt tggttctgac ttggacgcag
   100741 caacacaggc taagttgaac cgtggacgtc gtaccgttga ggtcttgaaa caacctgttc
   100801 acaaaccatt acctgttgag aaacaagtaa ccattcttta tgctttgaca catggtttct
   100861 tggatactgt tccagtagat gatattgttc gtttcgagga agagttccat gccttctttg
   100921 atgctcaaca tccagagatt ttggaaacca ttcgtgatac aaaagacttg ccagaagaag
   100981 cagtcttgga tgctgcgatt acagagtttc tcaatcaatc tagcttccaa taagaataga
   101041 ggtgtcagat ggcagtgtct ctaaatgata ttaaaacaaa aatcgcctca acaaaaaata
   101101 cgagtcaaat cactaatgcc atgcaaatgg tatcggctgc taagttaggt cgctctgaag
   101161 aagctgctcg caacttccaa gtttacgctc agaaagtgcg taaacttttg acagatatcc
   101221 ttcatggtaa tggagctggt gcttcaacta atccgatgtt gattagccgt tctgtgaaga
   101281 agacaggcta tatcgttatc acttcagacc gcggtttggt tggaggttat aattcctcta
   101341 ttttgaaagc tgttatggag ttgaaagaag aataccaccc agacggtaaa ggttttgaaa
   101401 tgatctgtat cggtgggatg ggagctgatt tctttaaggc tcgcggtatt caaccacttt
   101461 atgaattacg tggcttggca gaccaaccta gctttgatca agttcgtaag attatttcaa
   101521 aaactgttga aatgtaccaa aatgaactct ttgatgagct ttatgtttgc tacaaccacc
   101581 atgtcaatac gctaaccagt caaatgcgtg tggaacaaat gcttccgatt gttgacttgg
   101641 atccaaatga agcggatgaa gagtacagct tgacttttga attggaaacc agccgagaag
   101701 aaattctgga gcagttgttg cctcagtttg cagaaagtat gatttacggt gccattatcg
   101761 atgccaagac agctgagaat gctgcgggta tgacagccat gcaaacagcg acagataatg
   101821 ctaagaaagt catcaatgat ttgacaattc agtataaccg tgccagacag gcggcgatta
   101881 cacaagaaat tacagaaatc gtagcaggtg ctagtgcctt agaataggct ctagtccagc
   101941 tcgtatgaaa atgaacttag gacctagttg agctaggaac cgacagtatc ttatatagaa
   102001 taggagaagg agatgagttc aggtaaaatt gctcaggtta tcggtcccgt tgtagacgtt
   102061 ttgtttgcag caggggaaaa acttcctgag attaacaatg cacttgtcgt ctacaaaaat
   102121 gacgaaagaa aaacaaaaat cgtccttgaa gtagccttgg agttaggaga tggtatggtt
   102181 cgtactatcg ccatggaatc aacagatggg ttgactcgtg gaatggaagt attggacaca
   102241 ggtcgtccaa tctctgtacc agtaggtaaa gaaactttgg gacgtgtctt caacgttttg
   102301 ggagatacca ttgatttgga agctcctttt acagaagacg cagagcgtca gccaattcat
   102361 aaaaaagctc caacttttga tgagttgtct acctcttctg aaatccttga aacagggatc
   102421 aaggttattg accttcttgc cccttacctt aaaggtggta aagttggact tttcggtggt
   102481 gccggagttg gtaaaaccgt cttaatccaa gaattgattc acaacattgc ccaagagcac
   102541 ggtggtattt cagtatttac tggtgttggg gaacgtactc gtgaggggaa tgacctttac
   102601 tgggaaatga aagaatcagg cgttatcgag aaaacagcca tggtctttgg tcagatgaat
   102661 gagccaccag gagcacgtat gcgtgttgcc cttactggtt tgacaatcgc tgaatacttc
   102721 cgtgatgtgg aaggccaaga cgtgcttctc tttatcgata atatcttccg tttcactcag
   102781 gctggttcag aagtatctgc ccttttgggt cgtatgccat cagccgttgg ttaccaacca
   102841 acacttgcta cggaaatggg tcaattgcaa gaacgtatca catcaaccaa gaagggttct
   102901 gtaacctcta tccaggctat ctatgtgcca gcggatgact atactgaccc agcgccagca
   102961 acagccttcg ctcacttgga ttcaacaaca aacttggaac gtaagttggt acaattgggt
   103021 atctacccag ccgttgaccc acttgcttca agctcacgtg ccttggcacc tgaaatcgtt
   103081 ggagaagagc actatgcagt tgctgctgaa gtaaaacgtg tccttcaacg ttaccatgaa
   103141 ttgcaagata tcattgctat ccttggtatg gatgagcttt ctgatgaaga aaagaccttg
   103201 gttgctcgcg cccgtcgtat ccagttcttc ttgtcacaaa acttcaacgt tgcggaacaa
   103261 tttactggtc agccaggttc ttatgttcca gttgctgaaa ctgtacgtgg ctttaaggaa
   103321 atccttgatg gtaaatacga ccacttgcca gaagatgcct tccgtggtgt aggttctatc
   103381 gaagatgtga ttgcaaaagc tgaaaaaatg ggattttaag aggtgatcta tggctcagtt
   103441 aactgtccag atcgtgacac cagatggtct cgtctatgat caccatgcca gctatgtatc
   103501 ggttcgaact ctggatggtg agatggggat cttgccacga catgaaaata tgattgcggt
   103561 tttagcagtt gatgaagtaa aggtaaaacg tatcgatgat aaagatcacg tgaactggat
   103621 tgcagtaaac ggtggcgtta ttgaaattgc caatgatatg atcacaatcg tcgctgactc
   103681 tgcagaacgt gctcgtgata tcgatatcag tcgtgcagaa cgtgccaaac ttcgtgcaga
   103741 acgtgcaatt gaagaagcac aagacaaaca tttgattgac caagaacgtc gtgctaagat
   103801 tgctttgcaa cgtgctatta accgtattaa tgtcggaaat agactataag aaaaaatgaa
   103861 cttgaaaata ccaagttcat tttttatggt gttttaagga gcaaaacgga tgcagactgc
   103921 ttcgggaaca tggaagtcgt tggagagttc tgctagacga ccattgtcac aattacgttt
   103981 aaagacagtt gcattgtcag agtcttgatg gacaacaatg agaaattttt ggtcgggtgt
   104041 caaatcaaaa tcacgtggag tctgaccatg cgttggaacg atttctaata actctaagct
   104101 accgtccgca aggatggtat atactgcgat agaatcatgg ccacggttag aagcgtagag
   104161 gtatttaccg tctttagaga gatgaatagc agcggttcca ttaaagcctt cgtaagcttc
   104221 tggtaaagtt gaaataacct gcatacgttc aaattcgcca acgccatcgt agattaaaac
   104281 ttcgatagta ctattgagtt cacaaatgag ataagcgatt ttatagtggt tatggaaaat
   104341 gatatggcgt gagcctgctc ctggcttgct gtgataggta tagagcttag ataattttcc
   104401 ttcttgatcg aggtcatagg tgatgacttg gtcagttccc aagtcgcagg tcactagata
   104461 gtggtcaggt gttaaatctg tatagtgaac atggggggaa gcttgatttt catgtggacc
   104521 ttggccactg tgttgatcca tatcactaag tagaagacta ccatcttcct ggcgtttata
   104581 aacaaggact tgtcccttgt gatagttggc tgcgtaaacc aaatcacgct tttcatcgac
   104641 agcaacataa cagtggggag ctccttcttc aacaacatga tttaacacag tcccgtcagt
   104701 ttgataggct gcaattcccc ccttatcgtc ttggctacca acagtgtata aatgttggtg
   104761 ctggtcaaag gcaaggtagg ttggacttgg ctcagctgca aaaagttcta gatttgaaag
   104821 ctgaccagtt tctgtatcaa agtctgcctt gtaaatccct tgagaagtac gacgtgtata
   104881 agttccaaaa taaacagttt ctttcattac tatacctctg tgtaaagata agactattat
   104941 atcacaaaaa caagcaaatt aaagacattc aattagatgt aagcacttta aaaaagagtt
   105001 attttgtttc aaaaatggta taatgagaga acaatagaaa ggaagtattt atggagcaaa
   105061 aagagaaaca ttttagccta tcttggtttt tcaagtggtt tttagataac aaggcaatta
   105121 cggtattttt agtaacctta ttattgggat tgaatctttt tattttaagt aagattagtt
   105181 ttctattttc acctgtttta gactttatag cagttgtgat gttgccagtc attttgtctg
   105241 gtttgttata ttatttgttg aatcctattg ttgattggat ggagaagcat aaggttaatc
   105301 gtgttatagc tatcactatt gtctttgtta tcatcgctct ctttatcatt tggggcttgg
   105361 cagtcgccat tccaaatctg caacgtcagg ttttgacctt tgcaagaaac gttcctgttt
   105421 acttagaaga tatagatagg attgttaatg gattggtagc ccagcacctg ccagatgatt
   105481 tcagacctca attagagcaa gttttgacca atttttctag ccaggctaca gttttggcaa
   105541 gtaaggtttc atctcaggca gtcaactggg tgagtgcctt tattagcgga gcttctcaag
   105601 tgattgttgc cttgattatc gttcctttca tgctctttta tctcttgcgt gatgggaaag
   105661 gcttgcgtaa ctatttgacc caattcattc caagaaaatt gaaggaacct gttggacaag
   105721 ttctatcaga tgtgaatcaa cagttgtcca actatgttcg agggcaagtg acagtggcta
   105781 ttattgtagc agtaatgttt atcatcttct tcaagattat tggtctacgc tatgcggtta
   105841 cgctgggggt tactgctggt attttaaatc tggtccctta tcttggtagc tttctagcca
   105901 tgcttcctgc cctagtattg ggtttgattg ctggtccagt catgcttttg aaagtagtga
   105961 ttgtctttat tgtagaacaa actattgaag gccgttttgt ctctccattg attttgggaa
   106021 gtcaattaaa catccatcct attaatgttc tctttgtttt gttaacttca ggatctatgt
   106081 ttggtatctg gggagtttta cttggtattc cggtttatgc ctctgctaag gttgtcattt
   106141 cagccatttt cgaatggtat aaggtagtca gtggtctata tgaattagag ggtgaggaag
   106201 tcaagagtga acaatagtca acagatgtta caggctttgg aggagcaaga tttaactaag
   106261 gctgagcatt atttcgccaa agctttagaa aatgattcaa gtgatcttct gtatgagttg
   106321 gcaacttatc ttgaagggat tggtttctat cctcaggcca aggaaattta cctgaaaatt
   106381 gtagaggatt ttccagaggt tcatcttaat ctagctgcaa ttgctagcga ggatggtcaa
   106441 atagaagaag cctttaccta tcttgaggaa atccaagctg acagtgactg gtatgtctcg
   106501 tctttggctc tgaaggcaga cctttaccag ctggaaggtt tgacagatgt ggcacgtgag
   106561 aaattattgg aggccttgac ctactcagag gattctctct tgatattggg tttggcagag
   106621 ttggatagtg agttggaaaa ttaccaagcg gctattcaag cctatgccca gttagataat
   106681 cgctcgattt atgagcaaac gggcatttcc acctatcaac gaattggctt tgcctatgct
   106741 cagttaggga aatttgaaac ggctactgag tttttagaaa aagccctgga gttagaatac
   106801 gatgacttaa cagcttttga gttggccagt ctttattttg atcaagaaga atatcaaaaa
   106861 gccaccctct actttaagca gcttgatacc atttctcctg actttgaagg ctatgagtat
   106921 gggtacagtc aggctttaca taaggaacat caagttcaag aagccctgcg tatcgctaag
   106981 caaggattag agaaaaatcc ctttgaaact cgcctcttgc tagctgcttc acaattttct
   107041 tatgaattgc atgatgctag tggtgcagaa aattatctcc ttactgcaaa agaagacgct
   107101 gaggatacag aagaaatctt gcttcgttta gccactattt atctggagca ggagcgttat
   107161 gaggatattc tagacttgca gagtgaggag ccagaaaatc ttttgaccaa gtggatgatt
   107221 gctcgttctt atcaagaaat ggacgatttg gatactgctt atgagcatta tcaagagttg
   107281 acaggagatt tgaaggacaa tccagaattt ctggaacact atatctatct cttgcgtgaa
   107341 ttgggacatt ttgaagaagc aaaagtccat gctcacactt acttaaaact ggttccagat
   107401 gatgtgcaaa tgcaagaact gtttgagaga ttgtaagaat gtttaaacat atagaactgt
   107461 agtttatctc ttttgatagc tacggttttt atttgtatat ggtagaatct ttttacaaaa
   107521 atacttggta atcttgttta ttcatgctat aataggaaca attactttta ggaggtgcag
   107581 tatgtcttat ttatttgaga tattaccgag tttactgaat ggtgcgagca cgactgtaca
   107641 ggtctttgca ctggtcttgc tattttcgat tcccttgggc gttttgattg cctttgcctt
   107701 gcaagtccat tggaagcccc tccattatct gattaacatt tacatctggg ttatgcgagg
   107761 aaccccctta ctcttgcaac tgatttttat ctattatgtg ctcccaagta ttgggattcg
   107821 tttagaccgc cttcctgcag ctattattgc ctttgttttg aattatgcgg cttactttgc
   107881 agaaattttc cgtgggggaa ttgacactat tccaagagga cagtatgagg ctgccaaggt
   107941 cttgaagttt agcccttttg acagagtgcg ctatattatc ttgccccaag tgaccaagat
   108001 cgttcttcct agtgtcttta atgaagttat gagtttggtc aaggatactt ctttggtcta
   108061 tgctctcgga atttcagacc ttatcttggc tagtcgaaca gctgctaacc gcgatgctag
   108121 tctggttcct atgttcttgg caggagccat ttatttgatt ttgattggga ttgtgacaat
   108181 tatttccaaa aaagttgaga agaagtatag ttattataga taggaggctg ccatgttaga
   108241 attacgaaat atcaataaag tctttggaga caaacaaatc ctgtctaatt tcagtctaag
   108301 tattcctgaa aagcaaatcc tggctatcgt tggaccttct ggtggaggta agacaactct
   108361 tttacgtatg cttgcaggtc ttgaaaccat tgattcaggg caaatctttt ataatggaca
   108421 acctttagag ctggatgaat tgcagaagcg caacctactg ggatttgtct tccaagattt
   108481 tcaactattt cctcatctat cagttctgga aaatttgact ttatcgcctg tgaagaccat
   108541 gggaatgaag caggaagagg ctgagaagaa ggcgagtgga ctcttggaac agttaggact
   108601 aggaggacac gcagaggcct atcctttctc actatctggt gggcaaaagc agcgagtggc
   108661 tttggcgcgt gctatgatga ttgacccaga aatcattggc tacgatgaac caacttctgc
   108721 cctggatcca gaattacgtt tggaagtgga gaagctaatc ttgcaaaata gggaacttgg
   108781 gatgacccag attgtggtta cccatgattt gcagtttgct gaaaatatcg cagatgtatt
   108841 attgaaagta gaacctaaat aggaggaaaa atggatgaaa aaatggatgc ttgtattagt
   108901 cagtctgatg actgctttgt tcttagtagc ttgtgggaaa aattctagcg aaactagtgg
   108961 agataattgg tcaaagtacc agtctaacaa gtctattact attggatttg atagtacttt
   109021 tgttccaatg ggatttgctc agaaagatgg ttcttatgca ggatttgata ttgatttagc
   109081 tacagctgtt tttgaaaaat acggaatcac ggtaaattgg caaccgattg attgggattt
   109141 gaaagaagct gaattgacaa aaggaacgat tgatctgatt tggaatggct attccgctac
   109201 agacgaacgc cgtgaaaagg tggctttcag taactcatat atgaagaatg agcaggtatt
   109261 ggttacgaag aaatcatctg gtatcacgac tgcaaaggat atgactggaa agacattagg
   109321 agctcaagct ggttcatctg gttatgcgga ctttgaagca aatccagaac ttttgaagaa
   109381 tattgtcgct aataaggaag cgaatcaata ccaaaccttt aatgaagcct tgattgattt
   109441 gaaaaacgat cgaattgatg gtctattgat tgaccgtgtc tatgcaaact attatttaga
   109501 agcagaaggt gttttaaacg attataatgt ctttacagtt ggactagaaa cagaagcttt
   109561 tgcggttgga gcccgtaagg aagatacaac cttggttaag aagataaatg aagctttttc
   109621 tagtctttac aaggacggca agttccaaga aatcagccaa aaatggtttg gagaagatgt
   109681 agcaaccaaa gaagtaaaag aaggacagta agataaaata gtggctgaga ctacgttttg
   109741 attagcaaaa cgtagttttt tttgtaatct aggaaaacga taatagcgat tgaatctgga
   109801 taattgaata tggaatagcc cactgtgatt tctaaaacat tgttaaaaat tgatttgact
   109861 tccaaaatta aaatgttctg taatgaaata ctgatgtaac tgttttagga acaataaaac
   109921 gcataatatc aaggtttttg caccttacat tatgcgtttt tgtgatttta agacttgtta
   109981 gctgattttt tacaatccta cgaaatcttt gatttcttgt gctgacattg aagagtcgca
   110041 acggacgttg atttgtccat ctgtaatatg aacaaaacct ggtacagttg ggattccata
   110101 acgtgagcgg aatgcttgca aatcattgag ttggcttggt tcttcactat tgatgaagta
   110161 aatgtgagct ttggtttcag ctacgacacc tgacaatgta cctgcaaatt tacggcagta
   110221 agggcaagtt ttgcgaccga taaagaaggt tgcagtttct tttttatcaa gagcttcttg
   110281 cgcacgcaca actgtagtga cttcaaggtc tttgatgtta tctaaaaatt gttccatgag
   110341 attacctcgc tttcattgat aagtctagta tgccataaag tttctaaaat tgcttagatt
   110401 tgatacgaaa aaagatgagg ttggttggtc tcatctttta taggtcttta ttttacaaat
   110461 gcattgattt ctgcttcgat gttagtaatc ttagcttgtg attcttcgtt ggtttcccct
   110521 acaactgcaa tgtagaactt gatttttggt tctgtacctg aagggcgaac ggcaatccat
   110581 gaaccgtcag caagtgtgta tttcaacaca tcacttggag gagttgtcaa gtttgtaaca
   110641 gtaccgtcag caacagtagc agtttgtgcc ttgaagtctt ctacgacagt gatagctgtt
   110701 gcgttccatt ctgttggagc attgttgcgg aatttagcca taatcgcttt gatttgttca
   110761 gcaccatcga cacctgaaag agtaacagag attgtttttt ctgcgtagta gccatattct
   110821 ttatagattt cttcgatacc gtcagcaagt gtcaaaccac gagaacggta gtaggcagca
   110881 agttcagcaa ctacaagaac ggcttggatg gcatctttat cacgtacaaa tggtttaatc
   110941 aagtaaccga agctttcttc aaatcccatc atgtaagtgt ggttgtgttt ttcttcgaat
   111001 tcttggattt tttcagcgat aaatttgaaa cctgtcaaga cgttgaacat agttgcgccg
   111061 tagctttcag caatcttcgt taccaagtca gttgaaacga tagatttgca gagagcggca
   111121 ttttcaggaa gagttccagc gtttttgtga gcttccaaga tgtatttagc catgatagca
   111181 ccgatttggt tacctgaaag gttgaggtag ctgccatctt tttgaagaac ttcaacacca
   111241 acacggtcag cgtctgggtc agttgcgaca agaacatctg caccaacttg acgaccaagt
   111301 tcttcagcaa gggcaaaggc tgcttggctt tctgggtttg gagatgttac agttgagaag
   111361 tctgggtcag cagttgcttg cgcttcaaca acttgaacag agtcaaatcc tgcttgggca
   111421 agagcacgac gagccaacat ttcaccagta ccatgaagtg gtgtgtagac aatcttcatg
   111481 tctttaccaa attcttcaat caaggctggg ttgatgttta tgtccttaac ctctttaagg
   111541 tattctatgt caacagcttc gccgataact tcaatcaagc cagaagcttt ttcagtttcc
   111601 acatcagcaa cttcaactgc aaatgggttt tcgattgcac ggatataagt agtcaaagcg
   111661 tccgcatcgt gtggaggcat ttgtccaccg tcttcaccgt aaaccttgta accgttaaat
   111721 ggagcagggt tgtggctggc tgtgaccatg atacctgcga aacagttgag atgacgaact
   111781 gcaaatgata gttctggagt tggacgaagg ctttcaaata cgtaagattt gatgccgtgt
   111841 ttagcaagaa ctgccgcaga ttcaaaggca aactcaggtg agaagtgacg gctatcgtag
   111901 gcaattgcta caccgcgttc tttctcgttt ccaccttttg actcaatcaa acgagccaat
   111961 ccttcagtag cttggcgaac aacgtagatg ttgatacggt ttgtaccagc accaaccaag
   112021 ccacgcatac ctgcagtacc aaattcaaga tttgtataga aggcatcttc cttagttttt
   112081 tcgtccatat tttccaaatc ttgacgaagg tagtcaggaa gctccacaaa atcaacccat
   112141 ttctggtaat tttcttggta agacattcaa attctccttt atttttaaaa catttaatca
   112201 gtttgattat atcatttttt ttagttttag taaaacctta tctgcttcga aaatctcttc
   112261 aaaccaggtc agattgaatt ttggggttat atgatgttta ggctaggaaa aattcaattt
   112321 cagtaaaaaa agtaagtctt ctcataacaa aacattgata tagttactta gttttaaaca
   112381 agcatattat aataaagcta tggcatatag tactgatttt aaacagcgag cattagatta
   112441 catcaaagag gggcacagcc atgtcgaggc agccaagttt tttggtgttg gcgtcagaac
   112501 tctcttcacg tgggaaaaga aagacgtgaa caagaacaca tagagaggaa aaagcgagtc
   112561 gtcaaaaacc gaaagattcc tttagaggaa ttgaaagcct ttgtagaggc tcatccagat
   112621 gcttttttac gggaaattgc ggcacatttt gattgtgctg ttccttcagt atgggcagct
   112681 ttaaagcaga ttaaggtcac tttaaaaaaa gatgacgagc tttaaggaac aagacccaga
   112741 aaagtagcct tatttcttaa gaattttaat agtttaaagc acctagcacc tgtttatatt
   112801 gatgaaacag gaatcgaccg ctatctctat cgtccttatg caggggctcc tagaggggag
   112861 aaagtctatg aaaagattag cggacgtcgt tttgagcgaa tttcaattgt tgcaggacaa
   112921 gtagacggag agtttatagc tcccatgatt tacaagaaaa gcatgacaag cgatttcttt
   112981 gtggagtggt tcaaaacgca actcctacct gctttgaaga cacctcatgt tattgtcatg
   113041 ggcaatgctg gttttcatcc caagaacatt ttggatgaac tctgcatcca agataaacac
   113101 tttttcttac ctctaccacc ttattcaccg gatttgaatc ctattgagca agcttgggct
   113161 atcttgaaaa agaaagtgac ggatttatta agggaagttc caactatttt tgaatgtttg
   113221 gaatgctttt ttaaaactag atgactataa cggttctaaa ggaacctatc gagtagtcat
   113281 taaaactaag gatactgctg gttaagagaa gacggtatac aatcaaacca ttcaccgtgt
   113341 agccgaaatc gttcagaatg aagacttgta taaaaaaggt ttgaatgttg aacttgcgca
   113401 ccaacaaatt aagggatttt ttgaagcaga gtttaaaaat cgtattaatg gagttcttaa
   113461 tactaaaata aaaaatagta cattaaatcg tgtaaataaa aaaactatac accagagcaa
   113521 caaaaactcc atgatcaatt tgaagcagaa gcaacggaag atgctaaaaa acaaggcgat
   113581 attgtgttga atgttgacca ggatttcatg agcatatcta agtctaataa aagtggttca
   113641 gactggaaga aaactttcac agtgaggaca accaataggc tagcaaatga cttgaataat
   113701 gtcttgaaac aggctgataa agatactcct aataccccaa cttggctaaa ctcagctgct
   113761 tctaaagcta aagatgatga cagagcatat aaactactga agactcttat accaggagaa
   113821 aattacctat catgttaagg ataatcagct agaagtagaa acagataaat acacatatac
   113881 tgccgctaga aatggtagta aggaagttgg tattcaagag tcagatatag cagcaactct
   113941 aagtgccgat gaatataatt ctaatcgcca aacttttgag agagaataca aatacaaaag
   114001 caaatgccct taataatggt tgggctagat ctggttctga agagttcaaa aagttctccc
   114061 actttgtagg ggtagacaaa gggattgtgc gaacgaatgt actgactggt aaaaaactat
   114121 ctgataagat taggaaagaa gtgggctctg gagatagcaa actaggaaaa ggcggctatt
   114181 tctctactgg ggatgttcta ttaggaaaag atgttgtttc ttataccgta caagtatttt
   114241 cagagaataa tgaaagagta ggagtaaaca ctcaaagtca ccgtgttcag tataatctcc
   114301 caattctagc tgacttttca gtcatccaag atactgtgga accatcacga accgttgttg
   114361 aaaaaatcat tccaaaacta aatattcccg aagaagagaa agggaaaata accgaagaaa
   114421 tcaagaaaaa gaaaaaaacc tcagaattgg cagaactaat ctcagaaaat gtgaaagttc
   114481 gctatgttga tgaacaaggg cgtttgctat cattgaaaaa tgatactgga attggagaaa
   114541 aagaaagtga cggaacctac attaccaata aaaaacaact gattggtacc agctacaatg
   114601 tcacagataa aaaactcagt agcatgacta ctactgacgg aaaatattat acttttaaag
   114661 aagcagatac aaattctgca agtttaactg ggaatattgt aagcgaaggt agaacagtga
   114721 ccttagttta tagagaaagc gaagcgccaa ccactgctac agtaacagcc aattactata
   114781 aagaaggtag gcaagagaag ttggtagagt ctgttataaa agctgattta gcgataggtt
   114841 ctgagtatac cacagaatca aaaactattg aagggaaaac aacaactgag gacaaagaag
   114901 accgagttat cacaaggaaa acaacataca ccttggtagc aactcctgca aatgcgtacc
   114961 agaagacggt gcaacagttg actattacta ccgtgagaat gttgaggaaa cagtggttcc
   115021 caaaacagca acctctactg agacgaagac tataacgcgt atcattcatt acgttgataa
   115081 agttacgaac caaaatgtaa aagaagatgt tgttcaacct gtaaccttaa gccgtacaaa
   115141 aactgagaac aaggtcacgg gagttgtaac ctacggtgaa tggacaacag gaaactggga
   115201 cgaggttata tctggtaaga ttgacaagta caaagatcca gatattccaa cagttgaatc
   115261 acaagaagtt acgtcagact ctagtgataa agaaataacg gtaaggtatg accgtttatc
   115321 aacaccagaa aaaccaatcc cacaaccaaa tccagagcat ccaagtgttc cgacaccaaa
   115381 cccagaacta ccaaatcaag agactccaac accagataaa ccaactccag aaccaggtac
   115441 tccaaaaact gaaactccag tgaatccaga cccagaagtt ccgacttatg agacaggtaa
   115501 gagagaggaa ttgccaaaca caggtacaga agctaatgct accttggcta gtgctggtat
   115561 catgaccttg ttagctggtc taggattagg atttttcaag aaaaaagaag atgaaaaata
   115621 atagatttta gaatctagga accaggaaaa gctcacagat gtgggctttt ttcctggttt
   115681 tgagaacgag gtctttcgta aagaataaaa acgcttacaa gtctgttgaa ctgggaaact
   115741 atgaatccta tttttttaaa aatatttcca gaaatcagtt gctaaatagg gtaaaaattg
   115801 ataaaataag gaatatctaa aaaattttaa ggagaatcta gcaaatggat ttcacatggg
   115861 cactgaagta tgccactgaa tttttgggaa ctgccatttt gatcattctt gggaatggtg
   115921 cagttgccaa cgttgaactt aaaggtacga aaggtcacca aagtggctgg atcgtcatcg
   115981 ctgttggtta tggtatgggg gttatgatcc cagccttgat gtttggtaac gtatctggga
   116041 atcacatcaa ccctgctttc actctagggc ttgcagttag cggtcttttc ccttgggcac
   116101 aagtggtacc ttacattatc gcgcaagtct tgggggctat ctttggccaa gccttagttg
   116161 tggcaacata ccgtccattc tacttgaaaa ctgaaaaccc aaataacatc ttgggaactt
   116221 tctcaactat ttcaagtatt gaccatggta caaaagaaag tcgctatgca gcaactgtca
   116281 atggtttgat taatgagttt gttggttcat ttgttttgtt ctttgcagct cttggtttga
   116341 ctaaaaactt ctttggtgct gaagtgcttc aattcatgaa acaaaaggca atagaagcag
   116401 gacaaacagt tgatttttct gacttggcta ttaaagcaca ggtggctcca cacactgctt
   116461 caggactttc tgtggctcac ttggcacttg gattcctcgt tatggctttg gtaacatcac
   116521 ttggaggacc tacaggacct gccttgaacc cagcccgtga cttgggacca cgtctccttc
   116581 atgctttcct tccaaaatca gttcttggtg agcataaagg cgattcaaaa tggtggtatt
   116641 cttgggtacc agtagtagca cctatcgcag cagcaattgc ggcagtagct gtattcaaat
   116701 tcctttatct ctaagaaata gctcctttaa catttgagtg agcaccatct ataagtaaga
   116761 gaggatcaga ctggttctct ctttttgatt ttttagggaa atgaaagaaa ctctaaacaa
   116821 actcctctcc agcagtggtt tagaagtctc agtgggctat tccagcttca atgggctata
   116881 gtaggttgca gttgaaataa tagacccttg tttctaaaac attgttagaa attggtttga
   116941 attctccaat caaattgtgc agttttcatt ctactatata ttatcggaga tgggttccct
   117001 atcttgtaag tctgctttat agtgggttga agttggaata gtcctccctt ctttctcaaa
   117061 cattgtgagg aattgattta ccttcctcaa caaaatgttc agtttctatt tcattttgct
   117121 ataaaataag cgattagggg ggctattctt cgacctacat tgactctgct gagtcctatg
   117181 attgttatcg ttttatctgc aattttatac tcaatgaaaa tcaaagggca aactaagaag
   117241 ctagccgcag gttgttcaaa acacagtttt gaggttgtat agtagattga aactagaata
   117301 gtacacctta acttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgcc
   117361 ctattcttgt ttcattttac tatataaacc agagactgtt tacattttca gcaagtgagt
   117421 ggatggataa tgctgaaaac tccttgaagg ataagtctat ttagtacttt ctattagtta
   117481 gttaaatttt taccaagaat aattcacaaa aacgttgtaa aacacttgca atttagctga
   117541 aatttgataa aatagtaagg aaagttagac tgtattgcct actgtctatc tataaaatat
   117601 attttattgg aggcttttac tcaaatggca aaagaaaaat acgatcgtag taaaccacac
   117661 gttaacattg gtactatcgg acacgttgac cacggtaaaa ctaccctaac tgcagctatc
   117721 acaactgttt tggcacgtcg cttgccttca tcagttaacc aacctaaaga ctatgcgtct
   117781 atcgatgctg ctccagaaga acgcgaacgc ggtatcacta tcaacactgc gcacgttgag
   117841 tacgaaactg aaaaacgtca ctacgctcac atcgacgctc caggacacgc ggactacgtt
   117901 aaaaacatga tcactggtgc tgctcaaatg gacggagcta tccttgtagt agcttcaact
   117961 gacggaccaa tgccacaaac tcgtgagcac atccttcttt cacgtcaggt tggtgttaaa
   118021 caccttatcg tcttcatgaa caaagttgac ttggttgacg acgaagaatt gcttgaattg
   118081 gttgaaatgg aaatccgtga cctattgtca gaatacgact tcccaggtga cgatcttcca
   118141 gttatccaag gttcagcact taaagctctt gaaggtgact ctaaatacga agacatcgtt
   118201 atggaattga tgaacacagt tgatgagtat atcccagaac cagaacgtga cactgacaaa
   118261 ccattgcttc ttccagtcga ggacgtattc tcaatcactg gacgtggtac agttgcttca
   118321 ggacgtatcg accgtggtat cgttaaagtc aacgacgaaa tcgaaatcgt tggtatcaaa
   118381 gaagaaactc aaaaagcagt tgttactggt gttgaaatgt tccgtaaaca acttgacgaa
   118441 ggtcttgctg gagataacgt aggtgtcctt cttcgtggtg ttcaacgtga tgaaatcgaa
   118501 cgtggacaag ttatcgctaa accaggttca atcaacccac acactaaatt caaaggtgaa
   118561 gtctacatcc ttactaaaga agaaggtgga cgtcacactc cattcttcaa caactaccgt
   118621 ccacaattct acttccgtac tactgacgtt acaggttcaa tcgaacttcc agcaggtact
   118681 gaaatggtaa tgcctggtga taacgtgaca atcgatgttg agttgattca cccaatcgcc
   118741 gtagaacaag gtactacatt ctctatccgt gagggtggac gtactgttgg ttcaggtatg
   118801 gttacagaaa tcgaagctta attcgattta gttcccagaa gaacaattat ttaagtcaga
   118861 cactaaaaga atcttgcttg gcaaggttct ttttttagat attgaactaa tactaaatga
   118921 aaatcaaaga gcaaactata atatattgaa actagaatag tacacatcta cttctaaaac
   118981 attcttagaa atcgatttga ttgtcttgat tgatttgtct tgttcttatt tcattttgtt
   119041 atagaaagtt agctgcagac tgctcaaaac actgttttta ggttgtagat agaactgacg
   119101 aagtcagtaa catctatacg acaaggcgaa gctgacgcgg tttgaagaga ttttcgaaga
   119161 gtataatact agactcaaat caaaaagcat tatacaatag taatatgaaa tcaactaaag
   119221 aag
//
LOCUS       DAVLHM010000002        72741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLHM010000002 DAVLHM010000000
VERSION     DAVLHM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.002"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1150)
                     /locus_tag="VXE45_000142"
     CDS             complement(<1..1150)
                     /locus_tag="VXE45_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0788254.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNI"
     gene            complement(1397..1765)
                     /gene="rplL"
                     /locus_tag="VXE45_000143"
     CDS             complement(1397..1765)
                     /gene="rplL"
                     /locus_tag="VXE45_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0788255.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(1841..2341)
                     /locus_tag="VXE45_000144"
     CDS             complement(1841..2341)
                     /locus_tag="VXE45_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0788256.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(2380..2515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(2591..3850)
                     /locus_tag="VXE45_000145"
     CDS             complement(2591..3850)
                     /locus_tag="VXE45_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0788257.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKCPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(4242..5990)
                     /locus_tag="VXE45_000146"
     CDS             complement(4242..5990)
                     /locus_tag="VXE45_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788258.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLVIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(5992..7716)
                     /locus_tag="VXE45_000147"
     CDS             complement(5992..7716)
                     /locus_tag="VXE45_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788259.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(7774..8712)
                     /gene="msrB"
                     /locus_tag="VXE45_000148"
     CDS             complement(7774..8712)
                     /gene="msrB"
                     /locus_tag="VXE45_000148"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0788260.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(8860..8931)
                     /locus_tag="VXE45_000149"
                     /pseudo
     CDS             complement(8860..8931)
                     /locus_tag="VXE45_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9007..9876)
                     /locus_tag="VXE45_000150"
     CDS             complement(9007..9876)
                     /locus_tag="VXE45_000150"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0788261.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAAAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(9878..11164)
                     /locus_tag="VXE45_000151"
     CDS             complement(9878..11164)
                     /locus_tag="VXE45_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0788262.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(11315..12052)
                     /gene="mecA"
                     /locus_tag="VXE45_000152"
     CDS             complement(11315..12052)
                     /gene="mecA"
                     /locus_tag="VXE45_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0788263.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(12252..13286)
                     /locus_tag="VXE45_000153"
     CDS             complement(12252..13286)
                     /locus_tag="VXE45_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0788264.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(13315..14751)
                     /locus_tag="VXE45_000154"
     CDS             complement(13315..14751)
                     /locus_tag="VXE45_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0788265.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNNVSLLSTLLFLL
                     VSSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVM
                     VSILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRL
                     FERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSF
                     IAANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAM
                     GVLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPV
                     LDYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYI
                     MELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSE
                     SFFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(14767..15753)
                     /locus_tag="VXE45_000155"
     CDS             complement(14767..15753)
                     /locus_tag="VXE45_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0788266.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(15755..16858)
                     /locus_tag="VXE45_000156"
     CDS             complement(15755..16858)
                     /locus_tag="VXE45_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0788267.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(16848..17693)
                     /locus_tag="VXE45_000157"
     CDS             complement(16848..17693)
                     /locus_tag="VXE45_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0788268.1"
                     /translation="MNNMTDLKAIQARSLEMADYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(17972..19246)
                     /gene="psr"
                     /locus_tag="VXE45_000158"
     CDS             complement(17972..19246)
                     /gene="psr"
                     /locus_tag="VXE45_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0788269.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(19243..20091)
                     /gene="pheA"
                     /locus_tag="VXE45_000159"
     CDS             complement(19243..20091)
                     /gene="pheA"
                     /locus_tag="VXE45_000159"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0788270.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEGVTIPLQSQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(20088..20564)
                     /locus_tag="VXE45_000160"
     CDS             complement(20088..20564)
                     /locus_tag="VXE45_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0788271.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(20557..21840)
                     /gene="aroA"
                     /locus_tag="VXE45_000161"
     CDS             complement(20557..21840)
                     /gene="aroA"
                     /locus_tag="VXE45_000161"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0788272.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSASFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(21932..22270)
                     /locus_tag="VXE45_000162"
     CDS             complement(21932..22270)
                     /locus_tag="VXE45_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0788273.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(22281..23384)
                     /locus_tag="VXE45_000163"
     CDS             complement(22281..23384)
                     /locus_tag="VXE45_000163"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0788274.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            complement(23394..24560)
                     /gene="aroC"
                     /locus_tag="VXE45_000164"
     CDS             complement(23394..24560)
                     /gene="aroC"
                     /locus_tag="VXE45_000164"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0788275.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(24570..25637)
                     /locus_tag="VXE45_000165"
     CDS             complement(24570..25637)
                     /locus_tag="VXE45_000165"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0788276.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(25656..26510)
                     /locus_tag="VXE45_000166"
     CDS             complement(25656..26510)
                     /locus_tag="VXE45_000166"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0788277.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(26500..27177)
                     /locus_tag="VXE45_000167"
     CDS             complement(26500..27177)
                     /locus_tag="VXE45_000167"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0788278.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(27174..28337)
                     /locus_tag="VXE45_000168"
     CDS             complement(27174..28337)
                     /locus_tag="VXE45_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0788279.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(29022..30656)
                     /locus_tag="VXE45_000169"
     CDS             complement(29022..30656)
                     /locus_tag="VXE45_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788280.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSLMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVDPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(30637..31386)
                     /locus_tag="VXE45_000170"
     CDS             complement(30637..31386)
                     /locus_tag="VXE45_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788281.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            31565..33019
                     /locus_tag="VXE45_000171"
     CDS             31565..33019
                     /locus_tag="VXE45_000171"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0788282.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(33109..35727)
                     /gene="alaS"
                     /locus_tag="VXE45_000172"
     CDS             complement(33109..35727)
                     /gene="alaS"
                     /locus_tag="VXE45_000172"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0788283.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(35749..36234)
                     /locus_tag="VXE45_000173"
     CDS             complement(35749..36234)
                     /locus_tag="VXE45_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0788284.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(36509..36748)
                     /locus_tag="VXE45_000174"
     CDS             complement(36509..36748)
                     /locus_tag="VXE45_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788285.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(37017..38087)
                     /locus_tag="VXE45_000175"
     CDS             complement(37017..38087)
                     /locus_tag="VXE45_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0788286.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGSEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(38084..38857)
                     /locus_tag="VXE45_000176"
     CDS             complement(38084..38857)
                     /locus_tag="VXE45_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788287.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(38854..39660)
                     /locus_tag="VXE45_000177"
     CDS             complement(38854..39660)
                     /locus_tag="VXE45_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788288.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(39641..40798)
                     /locus_tag="VXE45_000178"
     CDS             complement(39641..40798)
                     /locus_tag="VXE45_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788289.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(40959..41864)
                     /gene="murB"
                     /locus_tag="VXE45_000179"
     CDS             complement(40959..41864)
                     /gene="murB"
                     /locus_tag="VXE45_000179"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0788290.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(41976..42728)
                     /locus_tag="VXE45_000180"
                     /pseudo
     CDS             complement(41976..42728)
                     /locus_tag="VXE45_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(42738..43469)
                     /gene="budA"
                     /locus_tag="VXE45_000181"
     CDS             complement(42738..43469)
                     /gene="budA"
                     /locus_tag="VXE45_000181"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0788291.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            complement(43953..44474)
                     /locus_tag="VXE45_000182"
     CDS             complement(43953..44474)
                     /locus_tag="VXE45_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcin A-M57"
                     /protein_id="HEV0788292.1"
                     /translation="MKFKKIVTSALVVLSLFSIMSPSIASVRVFADDVTTTEVSEIST
                     QEQKQIDDVANVLEQMFRNGVNEKNFTEYVYKNFSQKDIALAENELETNINNPYDRVP
                     WDEMGGCIAGKIRDEFFAMINVSLIVKYAQKKAWSELAKVVLRFVKANGLKTNIYIIA
                     GQLAIWAVQCGLE"
     gene            44905..46176
                     /locus_tag="VXE45_000183"
     CDS             44905..46176
                     /locus_tag="VXE45_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0788293.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(46196..47011)
                     /locus_tag="VXE45_000184"
     CDS             complement(46196..47011)
                     /locus_tag="VXE45_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0788294.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(47168..47821)
                     /gene="phoU"
                     /locus_tag="VXE45_000185"
     CDS             complement(47168..47821)
                     /gene="phoU"
                     /locus_tag="VXE45_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0788295.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(47833..48591)
                     /gene="pstB"
                     /locus_tag="VXE45_000186"
     CDS             complement(47833..48591)
                     /gene="pstB"
                     /locus_tag="VXE45_000186"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0788296.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(48604..49407)
                     /gene="pstB"
                     /locus_tag="VXE45_000187"
     CDS             complement(48604..49407)
                     /gene="pstB"
                     /locus_tag="VXE45_000187"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0788297.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(49418..50302)
                     /gene="pstA"
                     /locus_tag="VXE45_000188"
     CDS             complement(49418..50302)
                     /gene="pstA"
                     /locus_tag="VXE45_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0788298.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(50292..51209)
                     /gene="pstC"
                     /locus_tag="VXE45_000189"
     CDS             complement(50292..51209)
                     /gene="pstC"
                     /locus_tag="VXE45_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0788299.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(51209..52087)
                     /gene="pstS"
                     /locus_tag="VXE45_000190"
     CDS             complement(51209..52087)
                     /gene="pstS"
                     /locus_tag="VXE45_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0788300.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(52661..53965)
                     /locus_tag="VXE45_000191"
     CDS             complement(52661..53965)
                     /locus_tag="VXE45_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0788301.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(53966..54739)
                     /locus_tag="VXE45_000192"
     CDS             complement(53966..54739)
                     /locus_tag="VXE45_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0788302.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(54729..55007)
                     /locus_tag="VXE45_000193"
     CDS             complement(54729..55007)
                     /locus_tag="VXE45_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0788303.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(55007..55408)
                     /locus_tag="VXE45_000194"
     CDS             complement(55007..55408)
                     /locus_tag="VXE45_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0788304.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(55618..56235)
                     /locus_tag="VXE45_000195"
     CDS             complement(55618..56235)
                     /locus_tag="VXE45_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0788305.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(56225..56998)
                     /locus_tag="VXE45_000196"
     CDS             complement(56225..56998)
                     /locus_tag="VXE45_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0788306.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(57009..57746)
                     /locus_tag="VXE45_000197"
     CDS             complement(57009..57746)
                     /locus_tag="VXE45_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0788307.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(57751..58881)
                     /locus_tag="VXE45_000198"
     CDS             complement(57751..58881)
                     /locus_tag="VXE45_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0788308.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(58965..59354)
                     /locus_tag="VXE45_000199"
     CDS             complement(58965..59354)
                     /locus_tag="VXE45_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0788309.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(59370..59753)
                     /locus_tag="VXE45_000200"
     CDS             complement(59370..59753)
                     /locus_tag="VXE45_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0788310.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(59754..60542)
                     /locus_tag="VXE45_000201"
     CDS             complement(59754..60542)
                     /locus_tag="VXE45_000201"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0788311.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(60535..61470)
                     /locus_tag="VXE45_000202"
     CDS             complement(60535..61470)
                     /locus_tag="VXE45_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0788312.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(61600..61776)
                     /locus_tag="VXE45_000203"
     CDS             complement(61600..61776)
                     /locus_tag="VXE45_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0788313.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(61916..62623)
                     /locus_tag="VXE45_000204"
     CDS             complement(61916..62623)
                     /locus_tag="VXE45_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0788314.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            62774..63802
                     /gene="queA"
                     /locus_tag="VXE45_000205"
     CDS             62774..63802
                     /gene="queA"
                     /locus_tag="VXE45_000205"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0788315.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(64463..64852)
                     /locus_tag="VXE45_000206"
     CDS             complement(64463..64852)
                     /locus_tag="VXE45_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0788316.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(64956..65597)
                     /locus_tag="VXE45_000207"
     CDS             complement(64956..65597)
                     /locus_tag="VXE45_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002871528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0788317.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK"
     gene            complement(66311..66862)
                     /locus_tag="VXE45_000208"
     CDS             complement(66311..66862)
                     /locus_tag="VXE45_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788318.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(67261..68085)
                     /gene="nadE"
                     /locus_tag="VXE45_000209"
     CDS             complement(67261..68085)
                     /gene="nadE"
                     /locus_tag="VXE45_000209"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0788319.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(68082..69542)
                     /locus_tag="VXE45_000210"
     CDS             complement(68082..69542)
                     /locus_tag="VXE45_000210"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0788320.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(69658..70146)
                     /locus_tag="VXE45_000211"
     CDS             complement(69658..70146)
                     /locus_tag="VXE45_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788321.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(70136..70345)
                     /locus_tag="VXE45_000212"
     CDS             complement(70136..70345)
                     /locus_tag="VXE45_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0788322.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(70730..71458)
                     /locus_tag="VXE45_000213"
     CDS             complement(70730..71458)
                     /locus_tag="VXE45_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788323.1"
                     /translation="MKLNKLNFLKESIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYAWNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(71474..72265)
                     /locus_tag="VXE45_000214"
     CDS             complement(71474..72265)
                     /locus_tag="VXE45_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788324.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSMLMKILAQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        21751 a        16229 c        13353 g        21408 t
ORIGIN      
        1 taatgttgtt tttatttaaa atttcttcat agtaatcttt taaaatatca atctcatcat
       61 taaaattagt caaatcctga gagctagata actttgctgc aatgactgca atacgcggat
      121 tgcttttaga tatcgttttt atatgttcaa tttcttgatt ggtaaaatcg tttcgagaaa
      181 attgattgag taattcctta aaattatcat cttttataag ttctggctca atattattgt
      241 acccataaac tttaatatta ttgattacat cttttttagc ataatcacgt accgtaagaa
      301 taaaccgaat attactagtc gtgttcagta gcccaagtgt agaaatataa ttttgtgtag
      361 tattaacatc atcaataaaa acaatatttt ctttgtgtaa atttagattg cgttttacat
      421 cttggtaaat atcctgatta ttgctcttga cacaaataat gttatattta tttcgatcca
      481 gcaaagagca aatttcaatt gctaatctag ttttccctgt tccaggctta gcagatatta
      541 agaagattcg tttttcactt gatttaatgg tatttataat ttcacttaca tctccaatat
      601 agtcatttga tataggagca ttagttttac tctcatcatg aattcttatg aagtcattga
      661 tagaccaaac ttgctctgta gattcactga ttgatagata ctcttttgct aaatattgaa
      721 aatctatctt tgtaagatca ttagcaattt cattaattcc aatcaattct agatgataag
      781 gctcagccat tttttctaga tcttcttttt gtttaattgt tatatttgaa gaagtatgac
      841 aacaaataag tctcccaact ttatcttcag caatattttc ctctaaaatt tttttcttaa
      901 ctgactgaat gtctccttct aatttagata ttacagactt atgggtgcca tacataatat
      961 aaacatattt accattttcg acagcgtaag aatctgggat ccctttagtt gttttatctg
     1021 ttccttcctg tgagcctaat gaaacaatat taaaattgta ttttctactt aggtacgcgt
     1081 cacctagttt ttgaaacttc cctccctcta gctctttaat atgttgctca attttatttc
     1141 ttaaactcat tataaaaacc tttccagata agtatttcaa cataattata tcacactagt
     1201 caaaaccata aggtatagtt taattaacaa actcttgtac tacgttaatt tagagtagta
     1261 aaccaattat acaaaaatta tttatttcct aaacaactat ataaaaagtt tgcccctttt
     1321 taaacaaaaa gaaaaaccgc tactcctaag aatagcggtt taatcatgtt tttaagctac
     1381 taatgtagtt gctctattat ttaagagtaa ctgaagctcc agcttcttcc aatttagctt
     1441 tgatttcttc agcttctgca gttgcaacgc cttctttaac aagtgctggt gcaccgtcaa
     1501 caagttcttt agcctcttta agaccaagac cagtgatttc acgtacaact ttgataacgc
     1561 caactttttt gtcgcctgca gatgtcaatt caacgtcgaa tgaatcttta gcagcaccag
     1621 catcagctgc atcagctgca gcaacagcta caggagcagc tgcagttaca ccaaattctt
     1681 cttcgatagc ttttacaagg tcgttcaatt caaggattga agcttcttta atttcagcaa
     1741 taatgttttc aatgttcaat gccattgtta tttcctccaa ataagtttta aattttataa
     1801 tagttttttt cgtagctagg ctacgctgtg tagcttaaga ttaagccgcg tcttctttgc
     1861 tttctgcaac cgctttgact gcaagagcaa cgttgcgcac tggcgcttga agtacagaaa
     1921 ggagcataga aagaagtcct tcgcggtttg gaagagttgc aagtgcaaga atctcttctt
     1981 tagatgcgac agcgccttcg attgcaccac ctttaatttc aagtgcttca gcgtttttag
     2041 aaaagtcgtt caagattttc gctggtgcga taacatcttc attagaaaat gctactgcag
     2101 atggtccaac aaatacagat gcaagatctt caagaccagc tttttcagct gcacgacgca
     2161 agattgagtt tttaataact ttatactcaa cttcgcttcc acgaagctca cgacgaagaa
     2221 ctgtatcttg ctcaactgtc aaaccacgag cgtctacaac gacgatagat gcagcagctt
     2281 tcattttttc agctactacg tcaactagtt ccgctttttt agcaataatt gcttcactca
     2341 ttagtgtgtt cacctccgta attattttgc ttggggaatt tttcaaaaag aaaaacgcgc
     2401 ccaaacctag acacgaaagt acaatacgct tctttttaca tgatacgttt tgtcctcggt
     2461 aggatattta tgagtcgagc tcccctactg tcttaggcag tttttttaaa ccgtatataa
     2521 gtatagcata gtcaaaaaaa gaatgcaaga tttttgcaaa ctttttttaa aatttttcgt
     2581 aatttttctt ttaaagttct actgtcagga cttgaccttg cttaacaacc tgttctccgg
     2641 cgatataaac atcatctaca tcactagatt taactgcata aaccaggtga gacagcatat
     2701 tttcctgagg ttggagatga attttccctt gtggttgaat gaccagaaaa tctgcttgct
     2761 tgccgacttc cagacttcct atctgatttt ccattccaag gaccttagcc ccttcgattg
     2821 tcagtacctt gagagctgtt tcgattggaa actggctggc atccccactt ttcatcttct
     2881 gaagaagagc tgcagtcctt ccttcctcaa acatatctag attgttattg gaagcaaccg
     2941 agtcagtcgc aattccgact gctactcccg ctttttggag ctggataatt ggagcaattc
     3001 ctgatgccag tttgaggtta ctgataggat tgtgggcgat agccacttga gaagatgcca
     3061 agcgttcaat ttctctctcg tttaattcga ccccgtgagc aaatacggac ggatgatcta
     3121 aataacccag ttcttcaaga aaagcaaggg ggcatttgcc gtatcgtttg aggataattc
     3181 ctgactcctc cttggtctcc gccacatgga catggagcgg aatatttagc tcttttgcca
     3241 tttccaaact cgcttccagc aagtctctac tgcagctata cggagaatga ggtgctacca
     3301 taaccttgaa atttggattt ttatatttta agatttcatc tatgatggat cgagttctgc
     3361 ttatagtctc agcagttgtt tctgtctctg aagaaaagag agtcggagaa aaataacaac
     3421 gcatcttgga agttttcacc acctgataaa tttgctggat atccacacca ttgggattat
     3481 acatatcgtt aaaggttgtt gttcctgact ggagcatctc tgttagggct tctttaaccg
     3541 cattggtagt catgtcggga gtaaactcag attctgctgg ccagatatag tcattgagcc
     3601 attcatggag attgctgtca tctcggatcc ctctcagacc tgtcattgca gaatgggtgt
     3661 gacaattgac caaaccaggc ataatccaag ctccctgata gtctataatc tgctcagctt
     3721 gttctaaaaa cgctggctta tcttgaccga catagacgat ttgagaatcc ttgactgcta
     3781 agattccatc aagataaaca tggaaatttt gatcacaagt cacgatattt acatgctgaa
     3841 agactttcat tataggctcc ttttctaaaa gacaagttgt actctcttca aaccacttca
     3901 gattcacttt gccgtaggtg tggttactga cttcgtcagt tctatctgca acctcaaaac
     3961 agtgttttga gctgacttcg tcagttctat ctgcaacctc aaaacagtgt tttgagctga
     4021 cttcgtcagt tctatctgca acctcaaaac agtgttttga gctgacttcg tcagtcttat
     4081 ctacaacctc aaagctgtgc tttgagcaac ctacggctag cttcctagtt tgctctttga
     4141 ttttcattga gtattacagt gaacaatttt tctagctatt gtaacaaaaa agtcactcga
     4201 aggcaacttt tttcgtccat aaactttcaa aagagaatgg cttattcaga actaaaagcc
     4261 gcagcttttt gcatttggta atacttaccc tttctatcca tgagttcttg atggttacca
     4321 tattcaacaa tatcaccatc tactaagaca agaattaaat ccgcatcctg aatggttgac
     4381 aaacggtgag caatgatgaa gcttgtgcgg cccttcatga gttttgcaaa ggcatcctgt
     4441 accagcactt ctgtccgtgt atcaatggaa gaagttgcct cgtctaagat aagaatcttt
     4501 ggaataacca gaaagactcg ggctatggtc aagagctgag cttggccgac agagagagat
     4561 tctccagcat tttccaactt ggtatcgtat ccctgtggca actgttggat gaaaaagtct
     4621 gcattagctg ctttggcagc agcaattact tgctctcgac tggcttcagg attgccaaag
     4681 gcaatattat catgaatggt cccttgtgtg agccaggttt cttgaagcac cataccaaac
     4741 tgctgtctca atgatactcg tgtataatca taaatggatt gcccatccag caagatatct
     4801 cccgagctaa tgggataaaa acgcataagg agattgataa gagttgattt tccagcacct
     4861 gtcggaccaa cgatggctat cttactacca gctggaatat cgatagacaa gtccttaatc
     4921 aaaatttttt caggatggta gccaaaagag acatgtttaa aggaaatagc tcccttaact
     4981 tggtcactgg tcaagacttc cttacctgtt tcagccactt cagggctatc taagactcca
     5041 tagatacgct ctacgcaagc cagagcactt tgcaactcag ctagcactga agaaatatca
     5101 ttaaagggct tggtgtattg ctgaacatag ttcaaaaaag tcactaaacg accgacggtc
     5161 aaggttgaac ccatcatgat acgataagct cctactccag ctaaaagggc ataaatgagt
     5221 gcatttacaa agcgagtcga aggattgacc gttgaagaat aaaagatggc tgactgagaa
     5281 tagcctgagt agttgtcatg agcctcacgc aatctttgga taaattctgt ttgagcattg
     5341 aaggactgga ttatagtctg ctggctaagc gattcttcaa tcaactgagt ctgaattccc
     5401 ctcgtctctg tttgcttctg gaagagatga taggatctct tggcaataaa gcgtgaaatc
     5461 accatggaca gtggcgtcaa cagcaagact aagagagtca tgaggagatg aatttggagc
     5521 atggctagaa tactaaccaa aatcatcaaa acaccaatga aaaattggtt aaaaatcatg
     5581 gtcaagccag ctgccaactg ttcgatgtcc gtggttacac gactaaccat ctctccacta
     5641 ccttgcctat ctacaaaagc aatcggtaaa cgatggagct tatggatgat tcgctctcgc
     5701 aaatctctag tataagagaa gattagacga ttatagagga gaggattggc ccattgtacc
     5761 agagtatttc ctattaccac caagagcatc tggagaaaaa tctgccaaaa aactggtgat
     5821 gaaccagcca ctaggacttg gtcaatgacc tgcccaatca gaataggtag gtaaattgat
     5881 aagccaactt gggcaatagt tcctagaaag gctaggaaaa ggaggaaggg atggtttgct
     5941 aaatctacgg ctaaacgttt gagcgtctgg tttacagttt gtcgtttcat tctagtcctc
     6001 ctttccatgt tgggatgcat tgatttcacg atagacttgg ctggatttca tcaagtcatc
     6061 gtgcttgcca acagctagca actcaccttt ttccaagagg agaatctggt ccgccatctg
     6121 taaagttgag gttcgttgag agatcaaaat taagctcgtg tttggaaaat tttctctaat
     6181 agctttcaag agcttggact ctgtaatggt atccagtgcc gaggttgcat catctaggat
     6241 gataaacgga gcttggcgca agactgctcg ggcgatagac aacctttgtt tttgtccacc
     6301 tgagaaattt cgcccccctg cctcaactag ggcatccaaa agtccttcct tatcactgac
     6361 aaaatcctta gcttgcgcaa tctccaaggc ctgccagagt ttctggtcag atacttcttg
     6421 attgaaacct agagtcaagt tggaacgaat ggttccttta aagagttcga ccttttgagg
     6481 tacataggca atccaagacc gccactgctc caaattaaga ggactacgtc cattttgata
     6541 aaggtcaatg ttccccttgt ctactggata aagtccaagt aagagttgca ccaagcttga
     6601 tttaccagaa ccagtccccc caatgatacc aaggatttgt ccttgagtca tatcaaagga
     6661 aatgtctctc agagaaggct gggccgcatc aggataggta aaagtcaatt cttggacttg
     6721 taaaacccga ccactggtaa cttgcttttg ttctaattct gaatggatgt tttcgggaga
     6781 ttccgcaaag acctcctcga ttctcttggc tgagatatag gactggttga gggaattgat
     6841 cagcatggca agcttgacca attccaccaa aatctgtaag aggtaattga taagagcaat
     6901 gagagcacct tgactgagca ctcctccttg aattgaaata tagccttgcc agataataac
     6961 gagaagagtt ccattgacaa tcagataggt cagaggtgtt aataaactag accagaaacc
     7021 tgtcttttct tgtaatctag cataaacttg gttaagggtt tgaaaaatct gtaactctcg
     7081 tttttcttga ccaaaagcac gaataacccg catcccttgc aattgctggc gcgtttcctg
     7141 aaccagttgg tccgttttct ttctgagact actgtagaga ggattgacca atcgagatag
     7201 ccctacaatg acaatggtca aaatggcaac catgactaag aaccagaaag tcaactcagc
     7261 tgagattcga taagccataa aaatggcacc aaaaacgata atgggcgctc gcaaaaagag
     7321 acgcaggaat tgattgatac cagtctgaat ctggtaggta tccgaagtca agcgagtgac
     7381 caaactagaa gttgtcagac ggtctctgct gtccttggac aaggaaagaa tatgacgata
     7441 aagatcgttt gtcaattcct tagcaaagcc tactgctgcc tttgctgagt aaaattgagc
     7501 tatcaaggcc actaaaacgc caattactgc aaagataagg agcaggccaa tctgcatcca
     7561 gagatgacct tgatctccct gaggtaaaga ttggtcaaca atcccagcaa tcaccatggg
     7621 aaccaagagc tcaaaaacag cttctaacag cttgaacaag ggggctaaaa ttgattcctt
     7681 gatgtagggt ttgaagtaag ataataggtg tttcataaat cccttctatt catattctag
     7741 aaatgaagaa agtgggaagc cccactctct gttttatttg tttaagtaag gcaatagata
     7801 gccatatcct gctttttcca tctcatcctt ggccacaaag cgtaaagaag cagaattgat
     7861 acagtaacgg aggccgccta actcccgcgg tccatctgtg aaaacatgac ccaagtgagc
     7921 actgcctgaa cgagaacgaa cttcaattcg ctccattcca tggctcagat ccttgtaata
     7981 atgaatcaac tctttggaaa tcggacggct aaaacttggc caaccacaac ctgaagcaaa
     8041 cttatccttg gcaaaaaaga gtggctcacc tgtcgtaata tctacataaa tcccctcttc
     8101 aaaggtttgg tcataggcat tggtaaatgg agcctctgta gcagcttctt gtgtgacacg
     8161 ataagactct tcagatagac tggccttcaa cacctcttga ctaggctttt catagtttgc
     8221 tgcatcaatc aatggcttat cagcatcggt cacatcgata tgacagtaac ctgaaggatt
     8281 cttcctgaga tagtcttggt ggtagtcttc agccagaatg tagtggcgta attgctccac
     8341 ttctactgca atctttcgac ccagcatgcg ttcctgctcc tgtaccactg tgtagatagc
     8401 tggcaaatct gcttcatcct gataataaat cccagttcga tattggcgac cacggtcatt
     8461 cccttgttga ttgatagata gaggatcgat aactcggaaa taataaagta aaatctctct
     8521 gagtgacact tccttctcat cgtaaatcac ttggaccgtt tctgcatggt ctgtttcctt
     8581 gatcaactgg taattggtcg tttcgacttg accattagcg tagccaacac tggtttctag
     8641 cactccagaa atgcgtgaaa aatattcctc taggccccaa aaacaaccac ctgctagata
     8701 aatttctgcc atctttattt ctcctttatc acgtttttaa ctaatactct tcgaaaatct
     8761 cttcaaacca cgtcagcgtc accttaccgt atatatgtta ctgacttcgt cagttctatc
     8821 tgcaacctca aaacagtgtc ttgagctgac ttcttcagtt ctatccacaa cctcaaaaca
     8881 ctgttttgag cagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa
     8941 acttcttttc acaaaaagga tatgaaaccc tctggtcaag agtttcccca tcctatcttc
     9001 tattctttat tttgcttcta cacggacacc ttgggtatca actctcaagt catgcagttt
     9061 tcctttgaaa ggttgctttt ccaattctgc cttaattgtt ggcatcttgt catgagaagc
     9121 cagaaccata actgtcggcc cagcaccaga aaggtaggtt gcataggccc cattttcttt
     9181 ggtcacttgc ttaatcatcg caaattctct taccaagtcc tgacgatagc gctcatggaa
     9241 gaggtctccc tcgattgctt gcccagcggt caccatgtct cctgccaaca aggcagcaac
     9301 cgctacattg gcgatagaac ttgcagcagc agcttcctta taagacaatt ttttaggcaa
     9361 gacactacgg ctgtcgcgag tacgtaattc atagtttgga atgtaagcta gaaaatcaca
     9421 ctctggaaag tctgctacga tagcagagac ttgcccttca acagaacttg caataacgag
     9481 attaccataa atggctggag ccacattgtc aggatgccct tcaatcttgg tcgctaactg
     9541 caatttttca tggtctgata agttgagttg acccagttgg ttggctagtt caatcccagc
     9601 aacgataacc gagctggaag aacccaaacc gcgcgccaaa gggacatcac tggtcatttt
     9661 caagcgtctt ggttgcaagt ctggtacaat ttgcaaagcg attttgagca agagattacg
     9721 ctcatcatgt ggaatccatt tgccaatctg gtgttcaatc agccactcat ctcgttcttc
     9781 gcagacctca atttgaagat acttggttac agctacaccg accgagtcaa aacctggccc
     9841 gatattggca ctggttgcag gtacaataat cttcatctta ttctcctagc accttgaagg
     9901 tattcaagag gtcgaattct gaaaccttct tcaattcagc tgagacattt tcaagctggg
     9961 ctttattaat cttgtgtgtg atgataacga cacgcgcctt gtcaccctct ttgccatctt
    10021 gaaggatttg cttaaaggaa atatcttgag cattgaagat ttcagccaac ttcaagacct
    10081 gaccttttga gtctggagcc aagattgaga aatagtagtt tgctttgaca tcttcaggat
    10141 ttgccaagac caagtcacgg ctatattcgt tgaagtcttt gccaatggta ccatcattca
    10201 aacgacgaac gatacggaca atatcagcta caacacttgt tgcagttggt ttttgacccg
    10261 cacctggtcc gtagtacata gactcaccaa taccgataga ttctacaaag acagcgttca
    10321 ttacgccatt cacactagca agtgggtgcg ctttcggtag gaaggttgga gtcacttctg
    10381 cagcaatacc tgaagaagtt tcctcaatag aaccaaccaa tttcactacg taaccaagct
    10441 cttgagctac agctacgtct tctggtgtga tattgcggat tcccttgtgg gctacatcat
    10501 caaaggcaat cttcatgcca aaggcaaatt ggctcaaaat aaccatcttg taggctgcat
    10561 caatcccatc tacgtcattc gtcggatcgc tttctgcaaa tcctagacgt tgtgcttccg
    10621 caagagcatc atcgtaagac cagccttctt ccaccatctt ggtcaccatg aagttggaag
    10681 ttccgttgac tactccaagc acgcgcgtaa ttttatcaga agccaaggaa tttgctaaag
    10741 tacgaagaat tggaatccca ccagcaactg ctgcttcgta gtaaagtgct accttgttag
    10801 cttgagcgat ttctagcaat tctgcgccat ggacagctaa aaggtccttg ttagcagtaa
    10861 caacgtgttt tccagcttcc aaggcacgag tgataaaggt tttagcaggc tcaatacgcc
    10921 ccatcaattc cactacgata gtaatatcct ggtctgataa aatatcatcc acattggtta
    10981 caaagttaaa gtcattccct gctgcaagca agcgattttt ttcatcttca tccttgacca
    11041 ataccttagc aactttgata tctgaatgtg ctgattgatt gatttttcct ccattttcct
    11101 ttaggaggaa aggcacacca cttgcaacgg taccaaatcc tagtaaagca attttaactg
    11161 tcatctttat ctcctcgaaa ttttctaata tagccattat aacagaattt tgtgaaaatt
    11221 cctattatag taaatcacta tttcagtata aaaagaaaaa acgaatcaga cgattcgctc
    11281 ttcttaaaat ctgaaaatag ctttccagaa aggattagcc gattttttgc agattgagca
    11341 ctgcatcgtg actcatcaag acttgaccat actcttgtaa gactgagcga ctgatatcac
    11401 tatcgtctgc aaactcgcgc atacgggcca acagccaagc tggatatggg cttggatgat
    11461 tttcaatatc cactaaaatg gtcaaataat agcgctcgtt cattttgtag agttcagaag
    11521 tttccatttc aaaagtcact gtcttggcaa aagctaccaa gtcagccaac ttagcaaaag
    11581 aaaggatgta gtagatgtaa ggttctttct tactctcagc ttcttgttca gcctgctctt
    11641 gctcttcttc cttggcttca acttgctcaa gagattgaat ggcttcgata tcatccttgg
    11701 ttttgtctgc gatgcttttt tccagggttt tgataaattc atctggagac atttgagcca
    11761 attcttccat atctggcaaa tccgataagt cttcaaaatc tagattttgg tcaatctttg
    11821 acttggtcac aaagacatct accttatcag gttttggagt cacacggaag ctcaacatgc
    11881 ctgtatccag aaagctatca ggcatctcta gctcatccaa gatagcataa aagaactctt
    11941 ctgttttttc ttgaggaacg agaaagtcag caatctccat tccacgatcc atcaaatcct
    12001 ctaaagacat cgtgattttt aaagttgtat cactaatttg tttcattttc attgctagta
    12061 acctcatact ttcagttcta tctattatac tagattttta cgattttatc aaaagaaggc
    12121 tcctctatac ggatagattt tccctagggt ctttctatag gagactccaa gagaaaattt
    12181 ctgcagacag atagaaaaag ccttcaaaat cggctcttag ccgattttga agaccttata
    12241 catcagaata cttataattt aaaggttgct acaccgagga tagaacgatt taagtttctg
    12301 agaatttgaa gactttgctc aaatttctta taacgagtca ctccgtactc ttcaacaaga
    12361 aggactgtat ctctttccaa aagagatgat acatcctgca aatctacaaa atgcattcct
    12421 tttaaagctt cttgactctg tttcaattta tctaggatag ctttatttga gctaacgatg
    12481 gtcaattcct gtccagtatt tttgtatgac aaaacatctg ctaggttagc aattgttgta
    12541 atctctgtta caaaatcaat ttgatactga gaaaaatcac ctactctatt gattgttgga
    12601 ttaaagagat aaactaacac atttcccatc acaaccaaaa tcacacaaac cactccaata
    12661 acaactaaac gaagaatcag atttttcaca tttaagccaa gcgctgtttc accatttgcg
    12721 ttcaattctt tagagttgat ggtttccagt ttttcaattt tcacatttgc ataagcatgt
    12781 ttaaatttct caatcaaccc atcaattttt ttctctaaca agtcattggc atctttactt
    12841 gatgtcaaaa ttttcacacc aacccctgca tcgtcaatca tatagtagac ggtcaatttt
    12901 ttccaccaat agtcattcgt tgaatttttc aaggttgttt ccgtcgtgtc taattcactg
    12961 gcaatttttt tcaactcact gggttctaca tcattgaaaa gataagctcc attcaaatta
    13021 ccatcaatca atttcccata aaaatcacta taaccaccaa tttgatgatt caaaatcgtt
    13081 ttggccgaat cttctggagg agtgatttta tagataagat aagttgaata acttgttgta
    13141 tctttgacag tgtttttatt cctaactgct ttaattgtaa atggtacagc aatgagagca
    13201 aataaagcga tgagagctaa aatatttgct tttcgttttt tataaagatt tgcaaacaaa
    13261 tcagctactg aataatgttc aaacatgatt tttttctcct ttgtttagta gatactagtt
    13321 ttcctttgta agcatttttg ctacaaatat aatcacaaga acaattcccc agaattgcat
    13381 tgtaaataaa ttgaagaaac tttctgaaaa gctgcttctt ggcataaaga atagattatt
    13441 caagatgagt agggataaag caaataggat tgtccttgag cgataggcta cttgcagcat
    13501 ggctataaat aatacgccga gtaagaaact aagcagaaag actccaatca taccatagtc
    13561 ggtatacaac tccatgatat aactacttcc gataccatgc cctttcaagt attccttgtt
    13621 caagacaaga taggatagat tgtgggcata actattacta tcaatagcta gttccacact
    13681 attggttgta tgttcaaagg cttttcctcc gaaaatggct cccaaactcc cccttgcaaa
    13741 ataatcaaga acaggaccaa aagtaaaatt acggaaatct cggtaaggga ggctactgtt
    13801 aaatagaaaa cctcgagcca gaacaccaaa actagtccct tgtttataga taaagtcaag
    13861 taagatatcc cagaaacctg tatgagaaac ttggacatta tcccgtacat aattgagtac
    13921 tcccatcgct aacatgagaa taggagaacc tacaaaaatc gctaactttt ctttaaaccc
    13981 aatccatttt cctttttcag tttgctcccg cataaagtaa taaacaaaag caaataaaat
    14041 acttaaaata aagggatttc gtgtcccaat tgccaaatga atagtattag ctgcaataaa
    14101 ggagacaagc actgctgtgg cctgcaattt ctttggcttg gttgccagat acatacacat
    14161 tgcatagacc gtaaaggtag acaaaatgta ggtaaaataa ggcagtttac tttcaaaatt
    14221 tgcatagtag gcatagtagg aagtctgcaa acgatacaag agccgttcaa ataaccgaat
    14281 gaaatagaaa ggataggtta gaagaaaaac tcctagtgat acaaagcgta accgcttgat
    14341 ataaacctct tttagagaat ttcctatatt tgctactttt attttcttcc tagctatgaa
    14401 gtaacgagcc agaatgcctc ctgtggtcaa gcccagaatc gaaaccatga caactataaa
    14461 ggcaaaacga taggctattg gatgataggt atccaaagca ccatccctaa aataatcaat
    14521 ggtcggtctt gataccagaa atacaaaaat ggttaaatag aaaataaaat ggattaagta
    14581 atacttgata tcattccaac aagcaattaa gctactaacc aacaagaaca ataaagtaga
    14641 aagtaagcta acattattat tattattaaa cagatacaca attccactta ctagcgtcaa
    14701 ggcataactg actatggtca aactaaataa taatcgtttc ccatcaatca cttggtcacc
    14761 cccgttctaa tgtaattttt tagatttttc aatatttttc agtaataaga atcgatataa
    14821 ggaaatattt atgaataggg ccaaagcact aattcttctc cccttacgga aaattggatt
    14881 cctagaaata gcaaaggcat ggccttttaa aaaacgatga atctgagaat aggcttcaaa
    14941 ctgtttatac tgatcatcta gcaacatctt atccagaata aagaagtggg cataggccaa
    15001 tctgaaaaaa gcgacctctt tcaagtcagg atagtttttc acaacttcat tataaaactt
    15061 ttggtagata tcaatatagg ctaaatcctt ctctgcatag ggtttggtcg taatactatc
    15121 ccctctatgg aaatagtaat aatagggttt agtattaacc acatacttct tggccaactt
    15181 gattaaatca aaatggtaat aggcatcttc gtaaatcaac cccttaggaa aggatagggc
    15241 agttgcaatc tgtctcttga ttagcttatt gcaaatcgtc ccaggtattt tttcacctat
    15301 gaggtattcc tttagaaatg tttgagaatc acagacaaaa tagtcatcct gattggctga
    15361 ctgtgggctt tcatcattag catagacatt catgacacca cagcttgaaa catccgcatc
    15421 ttcttgaact aattgctcat ataagctctg aatcatttct ggatggatat aatcatctga
    15481 gtcaataaaa atcagataat ccccgtgagc ctgcttcatc ccatcatttc gtgcttgcga
    15541 caatccttcg ttctttttat gaagcactga caccctgtca tcttgttcag cgattgaatc
    15601 acacaagcga ccactttcat ctgttgcacc atcatcaaca agaataattt ccagattttg
    15661 ataggtctgc ttctgaatgg aagctatcga tttttctagg tactgcgcca cattatagac
    15721 tggcacaatc acactaatta atgcagtttc catgctactc ctctaatagt ttttctactt
    15781 gttcgatttg ttttgtaatt gtaaattgtt gaatgaattg gctagcctca tcgacatcaa
    15841 agtttgaggc agaagtcatg taattagtaa tcgcctgagc tgcctcttga ttgctctcaa
    15901 tgatttgtcc aaatcgtcct tcttgggata attcctcagc ccctccaacg tccgtagaga
    15961 taaaagggag tcccagactc aaggcctcca catacactcc aggaaaacct tcttgtttag
    16021 acatagacaa gagaactttc gtctgagata gatactgata aggatttttt tgataaccaa
    16081 ggaaatgtac atagtcctca atcccatact ctttgactcg ttttttcagt tcctcttcca
    16141 tatcaccagc cccgataaaa tagagatgat agttttttcc ctcttggtgt aataatcgta
    16201 tcacttccac tacacggtca gaacccttat tttcctcaat ccgtccgata gtacagatac
    16261 tttgaggagc aatctcgata tcgatcttct cttgagattt ttctagaata gtctgaaaat
    16321 catatccatt gtagattgtc tgtaatttag aagcataatc tggataaact tccttgatag
    16381 aattgctggt cttttttgaa atccctacaa ttgtattcgc agcatccaac tggcttctat
    16441 gtgattctct tttagagcta tccttaagaa gttcttcaat acttccatga atccaagata
    16501 tcttcttgac ttctcttctt ttagagaaca acagtggtgg attcataatg gtaaaagaaa
    16561 cttcaacatc ataatcatct tttacaagca aacgacgagc cagtcttgga aaataaattc
    16621 tcattctcca caaaaaagct cgtaaccatc tggtttggcg ataatcttga agggatttta
    16681 aaatgcgtac atgctttgga acagattcat atcccttgtc aaagtgctcc atttcaagaa
    16741 tatcaatatc atacttttct agatccagat ttgaaacaat ggttgataga atcttctctg
    16801 caccacctcc aagagaaaaa gaccacataa aaaataagat ttttttctta gccaccatat
    16861 tctcccttgt attctgtata agacttatcc atatcagcga tgacagcatc atgatgcggt
    16921 acctgcttgt ctgctggtgg aggcgtcata taatccccaa aagcagttct gagatagaca
    16981 tcatagccga ttggaatagg catctctgtt ccttcaaatg gcaagaaaag attgtcttca
    17041 aaagatgtga ttgggtactt gtttctcatg tagccaggac ctgagcataa ttctgtaatg
    17101 ccatcacaat cagccaaatc atacttagtc atttctttct cagctttttt ccagatgcga
    17161 taacggagag attttggagt caaacccagt aaaatgcgac ttccccattt catgagagca
    17221 ccatgctttt ctggaatagt ttgcgcacaa aagagtgaat aaatcaaggc ccaacgaacc
    17281 tgttttttcc gctcagctgg atctttcgga taataatcca aaggcaaaac atccaaggcc
    17341 agaccatgtg gcaaatccaa atcctgctga taaggcttga tacaggtggt ttccttgtca
    17401 cgaatggtaa taaaaagatt acgatcaaca aaatccttgt aactctttga caagaaataa
    17461 cgttcatctg cataacgagg ccataattct gctaatttct cataatcttt acgaggcata
    17521 aaaaagtcta ggtcgtcgtc ccaaggaata aatcccttgt ttcgaagggt accaatagcg
    17581 cctccgccac agagataaca gagcaaatca tgttctttac aaaaggccac aaaatagtca
    17641 gccatctcca gactacgagc ctgaattgct tttaaatcag tcatattgtt cattattctt
    17701 tctatcgtat cgtttcatta taccacaaac aaggggtgaa aatctattgc agactgtaaa
    17761 aaatcaaagc ctgactgcta tccaaatagc tatcaaactt tgatttttct gtcttatact
    17821 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtaggtatag gtaactgact
    17881 tcgtcagtct tatctacaac ctcaaaactg tgtttttagc agcctgcggc tagcttccta
    17941 gtttgcactt taattttcat tgagtattat cttatctcaa gcccatttga gcgagcttgg
    18001 tttgatattt gttttgatca accagcaagc ccaagcctcc ataaacatca taggcatcta
    18061 cccagtcacc cagttctgga atcgtcaatt tttcaatacc attttttgct ccatccaaaa
    18121 cagataaacc gtttgttagg aggaaagtat agggtacgtt ggttgaggtc atagcaaaaa
    18181 cctttccaag agcttcagaa ccagtgaaaa gtttagtggg atctttaatt tgctctaaaa
    18241 ttgctgttaa aacttgttgc tgtctttttg tacggccgta atccgcctca tcatcatcac
    18301 ggaaacgagc ataattgagc agggtcgagc cattcatctg ctgttttccg actttaatgg
    18361 tttgggttgg agactcagtc tcggtagcat ataaatcatc tccgactgta gcttctgtta
    18421 ggggacgccc attcaatgtt gaaaattgag catcaatcgt caccccatca gggaaaagcg
    18481 tgtcaatcgc tgtggcaaag gcctggaaat caaccaaggc gtagtactta atgtccaagt
    18541 caaaattatc tttcaagact tggcgaacca tttctgcccc tttttgcccc tcttgttctc
    18601 ctaactcgta ggctacgttt aacttgttat ctgtctgttt tctaccatta atcacttgac
    18661 tataaccatc tatatagacc aaattatcac gcatgaaact gactagcttc attttcttat
    18721 ctgagccccc gacatttaat accataatag agtcagttcg tgtctcaaca ctgttctggc
    18781 cgattcgacc atcagtaccc atgattaaaa tattaactcc atctctagtg tcctgaccat
    18841 taaatacttc tacttgagct gcccgggcat cagcagtttt ctttgcgcta gcatcttggt
    18901 aaccacgcaa aaacatgaat accatggcca aagccacaca gaccaaaagt gaaaaaatca
    18961 ccataaaaat tcgtttaaga cggagcttcc gtcttttctt ttttggaggg aaagagagtg
    19021 cttgtgattt ggattgtgag cgactccggt tcgcatagct tggtaagtca acctgctctt
    19081 ctctttcttg ttccaagcta gagctactat ttcccctagc aagagttagc ttttcttgca
    19141 aataggcaaa ctcatttttt tctctctcat tgagatagtg aatatttttt agcaaataat
    19201 cataacgcaa ctgctcatga tgacttaagg gattttcttt actcatcttc tctcctttcc
    19261 atggtctgat attggataaa taggataggc acccagaatt ttatactgga ttccaatcgc
    19321 ttctaattct ttttgggcaa agtggaccaa gtccttatcg gtataatcca catcgataat
    19381 gaaaaagtat tcacccagtg ctgtcttgag tggacgactt tcaatttttg tcaagtcaat
    19441 tcctcgccaa gcaaaggtcg acagggcttt ataaagtgca cctggaaggt tgtcaggtag
    19501 ggtcaaggct aaactcattt tttcagtttg tgattgcaag ggaatagtta caccttcagc
    19561 tcccaaaacc caaaaacgtg tgaaattggc ttccatttcc tgaatatcct cggcaatcag
    19621 ttccaatcca tattcttcag cagaacttct aggtgcaact gctgcaaagg gctgatctgg
    19681 atgttcggaa ataaaacggg ccgcataagc tgtactagct gttacctcga tttgagcctc
    19741 tggatattgt tcatcgatga atttctttcc ttgagccaag gcctgtggat gtgaaaaaat
    19801 cttttcaatc ttagtatggc ctggaaccac catcaactgc tgatgaatag gctgaacgat
    19861 ttctgctact gcttggatgt gagcctgatg aaaaagatag tccaaggttt catgaacact
    19921 accctcaata gaattttcaa ctggcaccac agaatagttc actaatcctt gctcataagc
    19981 cttgatgaca tctgtaatgt tggcaaaagc ctgcaattcc tcatgaggaa aagctgtctg
    20041 cacaacgtgg tgtgaaaatg atcccttggg acctagataa gctattttca tcttagttcc
    20101 tctataattt cctctgggct tagcttggtc acatccaaaa cccgactagc cacttcctca
    20161 taccaagcct gtctttcttg aaaaatagct actagttctt ccttgctatt atttagaaaa
    20221 agcggtcgct gattgtcctt atcagctgcg atacgtaggt agagggtttc aaaatctgct
    20281 ttcaggtaga tgttatctgt attagtcttg agtaagtcac gatttctctg agaaataacc
    20341 actcctcctc cagttgacac gacttggtct gtttgtagta aatcagctag gacttctgat
    20401 tctacctgac gaaaggctgc ttctcccttt tcagcgaaaa aattcgcaat ggacatacct
    20461 aggcgcttct caatcagagc atccatatca aggtaattag ggtccaagcc tcttgcaata
    20521 gtcgattttc cagcccccat aaaccctaat aacaccttag ccatgaatca agctctccaa
    20581 atcatcaaag aaactaggat agctggtatt gatggcttct gcacggtcaa gctccacctc
    20641 tccatctgca accaagaggg ctgcgatagc tgtcatcatg ccgatacggt ggtcaccaaa
    20701 cgtattgact ctagcaccgt gaagagctga tttccctttg ataatcatcc catctgccgt
    20761 aggagtaata tctgctccca tactatttaa ggcgtctgcc acaacctgaa tacggtctgt
    20821 ttccttgacc ttgagctcct cagcatcctt gataactgtt acaccttggg cttgagtcgc
    20881 aagcagggca ataatgggca attcatcaat caatcgtgga atcaaagcgc caccaatctc
    20941 tgttcctttc aagtcagaag actcaacaat caaggtagca gatttagcga ctggatcgat
    21001 ttcagttatt tccaattttc cacccatggc acgaatgaca tcaataatac cggtgcgagt
    21061 ttcgttgatc cccacattct gcagcactaa acgagaattt gggacaatca aacctgcgac
    21121 taaccaaaag gatgcactgg aaatatctcc tggtacgacc accttttgtc cagtcagttt
    21181 ttgaggtcct tgaactgtga ttttcttgcc atccacactt aaatggccac caaattgttg
    21241 caacatatct tcagtatgat tacgggtgca ctctttttcg ataataactg actccccctt
    21301 agcttgtaag gctgcaaaca tcaaggctga cttgacttgg gcagaggcaa ttggcaactc
    21361 ataatgaata ggtcttaggt ttttcgtccc ttttaagcga aggggaggca agtctcgttc
    21421 agtttgccct gagatgctga cgcccatttt tttcagtgga agggtcacac ggtccatagg
    21481 acgtttggaa agactatcat ctccaaacat ctctacttcg aaatctgcac cagcaaggac
    21541 acctgaaatc aggcgaatcg aggtgccaga atttcccata ttaagggcat tttgcggcgc
    21601 ttttaagcca gccatgccta caccttgaat ggtaataacc ccatctttat cctcaatttc
    21661 aacaccaagg tcacgaaaaa cctgcatggt cgaaagaacg tcttcacctc gcagaatatc
    21721 ataaaccttg gtctcaccct cagccaaact tccaaagata atggaacggt ggctgataga
    21781 cttgtcacct gggacgcgga tactaccatg taaatggcga atatttgttt ttagtttcat
    21841 actggacctc atacttgcaa tacttttacc tattttatca taaaaagcca gaaattcctt
    21901 aaaaattcct gactttagga tagttctttt cttatttcag caattctgaa actggttcga
    21961 aaacaatttt ttcaatgtca gaaaggtaaa tggccaattg ttgttgcttg gtaaagaatt
    22021 ctgacaagag gctatttcct tgaatctgtt taccaaagcc ttccatctta gcttggaagg
    22081 acgcatctgg catttgacct gtctgtgcta gtttttgaat ttcctcttga aaggcaagat
    22141 attctgtaaa gattttgctt gcctcagcat ctgctgcaat cgcatcttta gctgctttaa
    22201 cagccttgta ttctggtaat ccgcgtagac cgcgactgag ttcgtttgca ctatcgtaaa
    22261 tatttgacat gttcttctcc ttatttaatg acgactgtat agtcggtatt ttttgttatg
    22321 agatgctcgg ctctttccaa gtcttgagca tttttaaatg aaatttgtag gattccgtga
    22381 atatcctcac gattttcctc gttgatgtgg atgttaacca aggaagtccc acgtagcagt
    22441 tccaaaatcc gcaggatgac atcttcttca tcaggaacgt caacatagag gtcgtaagag
    22501 ctatccacac caccacgctt atggatttcc atggtctggc gttgttcacg cgcttggtta
    22561 aaaaagttcc aaatttgctc ttcatctccc ttactaatgg cctgaccaat cgattccaaa
    22621 cgttccttga aatcctcaat tctatccaga atggtctcgc tattggacaa gagaatggag
    22681 gtccacattc ctggctcgct ttccgcaatt cgggtcatat ctcgaaaacc acctgccgca
    22741 aagcgccttg ccatctcatg ctcttgagca tagaccgcag tctgctccat gagactagaa
    22801 gccaaaatat gaggaaaatg gctaatctga gaagtgacac gatcatgctc cttggcatca
    22861 atctcgataa aacgagcatg aagacctgaa agcagatcct tcatttcctt aagcgtgtcc
    22921 tgacttgtca ggcttgaagg tgtaaagata taataggcat tttcaaaaag attgacatct
    22981 gccgaagcag cccctgtctt gtgactacca gccatgggat gggccccgac aaagcgaaca
    23041 gacttgccag ccaaatactg ctccgccgca tccacaatgg ttgacttggt cgaaccagca
    23101 tctgaaataa taacgccttc tcgcaaatcc aaattggcca actccttaat gaaagcaata
    23161 gtttgtttga ttggcaagct gaggataatg acatctgcca aaggagcaaa actagcaaaa
    23221 tcatccgttg cacggtcaat catgccttct ttcaaggcga tatctctcga agcttgacta
    23281 cgattataac ctaaaatttc ataatctgga tgatcgcgtt tgataccaag tgccatagag
    23341 gctccaatca acccaagacc tgcgatatag attgtttttg ccataggaac tccttaatag
    23401 ttctttgtat agtctcggtg tttggctacc gcttctttta gttcctcaag attatctgat
    23461 gagaattttt cgaggatctc ttgcgccaga accgttgcta caactgcttc catgaccatt
    23521 cctgcagctg gaagagcagt cggatcactt ctctccacgg ttgccttgta aggttcgtgg
    23581 gtttcgatat ccacactcat aagaggttta taaagagtag gaatgggttt catgacccca
    23641 cgaacaacga tgggttgccc attagtcata ccaccttcaa aaccacctag attattggta
    23701 cggcgagtat aaccgtcttc tttagaccag agaatttcat ccataacttg gctgccttta
    23761 cgataaccag cctcaaagcc aagaccaaat tccacccctt taaaggcatt gatagagaca
    23821 acagcttgag ccaatcttgc atccaatttt ctatcccatt ggacatagga accaagacca
    23881 actggaactc ctccgacgac tgtctccaca accccaccga tggtatcacc atcacgtttg
    23941 atttggtcaa tatagtcctt gatttcctgt tctcgttctt ggttgacaat agaaacttca
    24001 gactgggcag ctctttgctt aatttcagcg actgtcagat tttcaggaac atctatttcc
    24061 ttaccaccaa agaccacgac atggttggca atctccatat ccagctcagc caagaggcgt
    24121 ttggctactg caccaactgc cacccgcatg gtggtttcac gagctgatga acgctccaaa
    24181 gaatttcgca aatcatcaaa acggtactta atccccccaa ccaaatcggc atgacctggg
    24241 cgaggatgag taattttccg cttgctttta aggcggtctt caatgtcctc cgcagacatg
    24301 atgtccagcc atttctggtg gtccttattg atgacatcca tagtaatagg cgcccctgtc
    24361 gtcttcccgt ggcgaacacc cgaagtaaag acaacctggt cactctcaat cttcatacga
    24421 ccaccacgac cgtagccacc ctgacggcgt ctaagatcct cattgatatc ctcagctgtc
    24481 aatggaagtc cagctggaat tccctcaata atagctgtta gacgggggcc gtgtgattct
    24541 cctgcagtta aatatctcat acactctcct tattttacca agtagtcttt catctcttcc
    24601 agagaaactg ggtgaatggt cgctgaacca agctctggca ccaagaccaa tttcaaggtg
    24661 ttaccacgcg ctttcttgtc atgagtaaga gcctgataaa gcttgtcaac tttccaattt
    24721 tcatagtcaa caggcaagcc gaatttctga cacatctctg tgatagattg ggtaatgcca
    24781 gctggcatga ggcctttttc ctcagcaacc ttggaaatct gtaccattcc catggcaaca
    24841 gcctctccat gcatgacctt gccataaccg gcagtcgctt cgatggcatg gccaatagtg
    24901 tggccaaaat tgaggtaaag acgaatacca ttgtccaact catcttcaac caccatcttg
    24961 cgcttcacct gacaagaatg ttcaatcaag gtctctgcat gttccaaaat actctcaaca
    25021 gaaccattca gtcccgtcaa gagagcccac agttctggat cctcaatcaa gccatacttg
    25081 ataacttcac ccatcccttc aatcaactct ctttttccga gggtttcaag aacaagtgga
    25141 tcaatcagaa ccccatctgg ttgggcaaag gtccccacca tatttttagc aaatggtgtg
    25201 ttaacgcctg tctttccacc gatagaagaa tcaacctgag ctgtcaaact agtcggaatc
    25261 tgaacaaagt gaataccccg catataggta gaggctacaa atccagccag gtccccaaca
    25321 acgccaccac caagagcaac gattccatcg ctacgagtca gaccttgctt gactagaaat
    25381 tcatagactt tctgaacagt agttaaattc tttctttctt caccttctaa gaaatcaaaa
    25441 acagctacct gaaaaccagc atcttctagg ctgagcttga ccttctctgc atagagagag
    25501 gctacatggt tatctgtcac aatgactacc ttttgcggtt gccagagttc tcgcaaccac
    25561 tgaccagcct gggccataca acctttttca atctgaatat cataaggatg atgaggaata
    25621 tcgattctga ttttcatagg agagtctccc tttctttatt ggtatttttc tgttaaagac
    25681 tgccaaatct cttctgtcgg catttccttg cctgtccaca gttgaaaagc ttctgcagct
    25741 tgatagagca acattcccag accattgact gctggattgc cctgacttct agcccatttc
    25801 aaaaacggtg tttcaaaggg ttggtatatg atatctgcaa ctaagagagt ttctggtaag
    25861 actatgtttt caggaacagg agaggattgg ccatccatgc ccacactggt ggcattaact
    25921 agcaaatccg actcggcaat ccttgcttgc agttcagaaa catattctaa agcacacaaa
    25981 tccactttaa aacctgtctg ctcctgtaac ttgtctaggt aaggtcttgt tttttccata
    26041 gaaacggaac gaacaaagac cgaaatctga ctgacgccat ccaaaatagc ctgtgccaag
    26101 attgatttag ccgcaccacc tgcacccagc agggtcatct ttttacctga aattgtaaaa
    26161 gaaggcaagc acttaaaaaa tcccttgcca tctgtattat atccaattaa attgccattc
    26221 tcattgacaa ccgtattaac cgcaccaatc aagtgcgctt catcgctcag cttatccaaa
    26281 taaggaatca cctgctcctt atagggcatg gacagattga tgccaaacat ctggtagcga
    26341 cgaatattgg ccactgtttc tgccaagtca ctcgcttcaa tctcccaagc cacataagca
    26401 ccgttggtag ctgtcgcctc aaaggctcta ttgtggatga agggagaaat agaatgctta
    26461 ataggattgg caacaactgc agctaaacgt gtatagccat caagcttcat ccaaaatctc
    26521 cctgattttt ttcatgctag ctagagaaat ctgcccaggg gcactaacct catccagact
    26581 ggcaaaagac caactcgaac cagtcacatc cgcagtgata cgagagacct tgcccacctt
    26641 acccatagaa atggtcacat attcctgttc aggattgagg gttttaaagc ctcgtgtata
    26701 gttcatcaag tctaagacat cctgctccgt gtgagccatc accgcaacct taacaagttt
    26761 tggatttagg atcgtcaact ctgacaagat ttccatcatg ttctcaggtg tttcttggaa
    26821 attatggtaa ctcaaaacaa gatttgggaa gtccagcatt tcctcaaaaa catccttgta
    26881 gctatagtac tcaaaatcaa tatagtctgg ttgatagagt tgcgcaactt ccttgattag
    26941 atggatatac tcttctggag aaaggtcgat ttctccacct tcggagcgag ttcgtagcgt
    27001 gaaaaccaac tcacggcctg cgaatttttc aaaaatggct ggagctacct gcaaaatcgc
    27061 ttctttaggc agatagtcgg cacgccattc aatgatgtcg gcatccaggt acctcgtggc
    27121 atccagagcc tgagcctcct ctaaacttct tggcattact gaaacgatta atttcattta
    27181 ctaaccttca tactaatcac cttgaggtaa ttactacttt catctttttt attataggca
    27241 aaatctgctg gaagaccata tttgtttaaa atctggtaac ttcttcctgc aaaaccttta
    27301 tcaatttgtt ctgtaaattt ctgacgggaa acattggcag cattggtact ggcaatgata
    27361 atccctcccg gatttaaaat ctcaagactc tgggaaatca acttgtgata atccttggcc
    27421 acagagaaag tttgtttttt attccgagca aagctaggcg gatctaggac aatcacatcg
    27481 taggtcaagt ctttgcgttt ggcatatttg aaatactcaa agacatccat gactataaaa
    27541 cgatgctcgt ctgtgctgag cccatttgcc tgaaaatgcg cttgagacaa ttctcgtgaa
    27601 cgtttggcta gatcaacaga agttgtctgg ctagctcctc ccatggccgc agctactgaa
    27661 aaagccgctg tgtaggaaaa catattgagc aaggatttac ccatagccaa gccgtcaact
    27721 aaactaccgc gaacctcatg ctggtctagg aaaattcctg tcatcaagcc atcattcata
    27781 aagacttgat acaggacacc attttctaaa acagtgaaaa agtcaggtgc ttcttgacca
    27841 taaacatggg cagattcata gtccaaaccc ttaaagcgga ttttctcata agctcctaaa
    27901 acctcaggga aaacctgtct aaaggcttct gatatagtct gacgaatctg ataaacataa
    27961 gagttatacc aagaaaagac ggcgtagtcg ccataaaggt ccactgtcag acccccaaag
    28021 ccatctccct cttgattaaa gagacgaaag gcagttgtca aatcatcttg atagtaggcg
    28081 tttctctttt ctttggcttt tctaaacaac gtttcaaaga aagcttgatt gaaggccacc
    28141 ttgtctttgc tgataaacca gcccaagccc ttgttttgct gagaaaggta ggcagtccca
    28201 agaaagtttc cttcctgacc ctgcacctct acttcctgat ccttaagatt gacattctca
    28261 agatcactgg cttctagtaa aactagcccc ttagcaagct tcttttcaac ccttttgctg
    28321 actcttattc tattcataac taccattata tcaaactttt agacaattct caaaaaagaa
    28381 actacccttg cttttttact cttcttttaa aaaatggtat actagacttc ctgcaaaact
    28441 aggaagtaaa tgtgtaagaa tcacagtaaa aaatgctctt ccgtcttgga ggagcatttc
    28501 tttttatcaa cgaaaatcaa atagcaaact atgaaactag cctcaggtta accgtgagat
    28561 tataggtaga gaggttgtat cagcaatatg tgtctgtcaa atttagtgac aaaggtagta
    28621 gaagaaagat gaagaaataa atcagcttca gtagatatct ggaaaatttg attttataga
    28681 aaagcctttt gttacaaact caatatacta tcaataaata atattataga agcaacaata
    28741 attaaaattt cacctatttg catcattcta tttcgaactc taaatatatg ttctatcaaa
    28801 aatacttgga tcacacacat tataggaatt aacgtttttg aaattgaaaa atatcccaat
    28861 aaataaacta taaacaacaa taatagaact atattatatt tcttattcaa aacattcctc
    28921 cctatatttt tgattaccaa tcttaatcat ttacaactac attctaacaa actataaaag
    28981 cgtttgtcga attgaattta tcaagcaagc aaccaaccag ctcatctttt ttctatttct
    29041 gccaatatgc gtgacaggta ataatgatag ccaaaaatag caagagcaag caagacgata
    29101 agagctccta ctcccaagtt gatggcaagg ataggggaga gagactgaac caagaatatg
    29161 ctcccaatta caagggccat caggattgca ctataaataa acaataaaac tatggcgact
    29221 atgccatttg aacgattcac caggtccgta atgctactcc aattggttga cagattttta
    29281 acgtccttaa agtaatggtg gcaagaaagg atgacactgg caaggatcca tgccacaata
    29341 aggtaaatca tcgaaatgat gggcaagcct agatatagag aaagaccaag caaagtcaga
    29401 actggtaaaa aggactggac agcatatata atccaaaatt tcactttcac ataacgagca
    29461 aagtcaaagg gtaaactctt aagaaaatca acattttccc tctccaagga caaggcaatt
    29521 gaatgcaggc tggtgatatt gttattgaca actgctataa acactcctac aaaaaacaag
    29581 ggtaaccagt atggaggatg aatgtctgga actatctgag aatctcggat tttggaaatc
    29641 agaccgatca tcatgagata aggaaagaaa gcacttgtaa aaagcactgt aaccacgcca
    29701 gtaccctgtc ccaagagggt gaggtggtag cgtaaaacca tgcggaaaaa tcccttttta
    29761 gtggttgaaa ttctctcctt gctgcgacgt tcttttttga ccttctcctc actattaagc
    29821 aggatcacgt cataaaaacg aggaaggacc ttctttttgg tcagataaag caggaagaga
    29881 gttagtccta tccaagcgag cagacccaat atggcttctg tcgaaaaagg atccactgct
    29941 attttgtaaa agatatgaag aggataaagg agaaatggaa tgtctctaac tttgtcaaca
    30001 atacttccaa aagtcgactg aagaaagaag ataaatatta aaggtatgag aactcctatc
    30061 ccaatcatca cattcgaaaa aatagactga tactttctga agaccctagt ttgagccaag
    30121 aaatgcactg ccactaccat cactagagcc acagagacaa ataataaggt caaggacagt
    30181 agcatcaaag gcaaacccag ccatagagaa ggagctagcc taatgtagag gaccagaaaa
    30241 taagctagga ttggtacaat tccagttaga gctggcaaaa ggacagacag tcctttagca
    30301 attataatct ctgattcttt aaaggcatag ggcctatacg atatcaaatc cttactctca
    30361 taaaagacat tgtaaaaggc cgttaaagaa gttgaaaagg caatcactag taaaatagca
    30421 atcatcaagc taaaataaat aggtatttcc tcaaaaggaa aatgaatggc tatattacta
    30481 aaacagatga tcatcaagag actggaaaaa atgtaagaac ttaagactct agcggaaaca
    30541 tttacttttt tcccaggatt cttagcctgc ttctttcgta gattagccag attagcttct
    30601 tgagatgaat aaaggatatt gatatcaact aattttttaa tgaccttgag acgcatccgc
    30661 aacctcctct tttctaccag caagactaag gtagatactt tccaaagact ggtctgggta
    30721 atcttttctc aagtcctcta cactaccaca ataaatcaaa tgcccctttt tcaaaatggc
    30781 aatccgatca cagacttgct ctgccacctc taggacatga gttgaaaaca agactgtctt
    30841 ccctttttgt gcatgttcct tcatcatctg tttcaaatca aaggcagcct ggggatccaa
    30901 accagtcaag ggttcatcca agacccaaat atcgggatca gacaagagtg ctccgatgac
    30961 aaagactttc tgacgcattc cgtgagaaag agtttcaata acctgatagc gattttcagc
    31021 aaaatcaaaa acgttcaata gcctagctag actagcctcc aagtcagatc tactcagatc
    31081 ataggatgag gcgatcaatt cccaaaattc attggccgtt aagcgtaaaa ataagtcagg
    31141 cgagtctgct acgtagccaa tctttcgttt aatagccaag cgattttccg ataactcctg
    31201 accgtctacc aaaatacgac cactgctggg tgaaatgata ctgactaggg attttatagt
    31261 ggtcgatttt ccagccccat tatgaccaat caagcccata atctctccat tttcaatctg
    31321 caaattgaga ttactcaagg cctttttatc accatacaac ttactaacat tttgaaattc
    31381 aatcatggga caactcctat ctttatctgt attatatatc gctatactag cactttgata
    31441 caaaaaaatc aatactttat tttaagtagt taaaatagtt tccttctatc ttacgcaaac
    31501 gtttgcgcta atagatactt tatgatagaa taaagaacaa gattgacaag taagaggaaa
    31561 cattatgcaa aatcaaacac tcatgcaata ctttgaatgg tatctgcccc acgacggtca
    31621 acactggacg cgtctggctg aaaatgctcc acacctagct catctgggga tcagtcacgt
    31681 ctggatgcca ccagccttca aggcaaccaa cgaaaaagat gtcggctatg gggtctatga
    31741 cttatttgac ttaggagagt tcaaccaaaa agggactgtc cgcaccaagt atggtttcaa
    31801 agaagactat cttcaagcca ttcaagccct taaagcgcag ggaattcaac ctatggccga
    31861 tgtggttctc aaccacaagg ctgctgctga tcacagggaa gcctttcaag ttattgaagt
    31921 ggatcctgta gaccgtacag ttgaacttgg agaacccttc accatcaatg gctggactag
    31981 ttttaccttc gatggtcgcc aagataccta caatgacttc cactggcact ggtaccactt
    32041 cacaggtaca gactatgatg ccaaacgccg taagtctggg atttatctga tccaagggga
    32101 caacaagggc tgggctaacg aggaattggt cgataacgaa aacggaaact acgactacct
    32161 catgtatgcc gacctagact ttaaacatcc tgaagtcatc caaaacatct atgactgggc
    32221 tgattggttc atggaaacga ctggtgtagc tggtttccgt ttggatgccg ttaagcatat
    32281 tgactctttc tttatgcgca acttcatccg cgatatgaag gaaaaatacg gtgacgattt
    32341 ctatgttttt ggtgaatttt ggaacccaga caaggaagcc aatctggact atctcgaaaa
    32401 aacggaagaa cactttgacc ttgtcgatgt tcgtctccat cagaatctct ttgaagccag
    32461 tcaagctggc gcaaactatg accttcgtgg cattttcaca gatagcctgg ttgaactcaa
    32521 gcctgacaag gctgtgactt ttgtcgacaa ccacgatacc caacgaggac aagcccttga
    32581 gtctaccgtt gaagaatggt tcaagccagc agcctatgcc ctcattttgt tacgccaaga
    32641 cggccttcca tgtgtctttt acggagacta ctatgggatt tcaggccagt atgctcaaga
    32701 agatttcaaa gaaatccttg accgcctcct agccatccga aaagatttgg cctatggaga
    32761 acaaaatgac tactttgacc atgctaactg tatcggttgg gtacgttcag gtgctgaaaa
    32821 tcaatcccca atcgcagtcc ttatctcaaa tgaccaagaa aacagcaagt caatgtttgt
    32881 cggtcaagaa tggactaatc aaacctttgt agatttactt ggtaaccacc aaggtcaagt
    32941 tacaattgat gaggaaggtt atggacaatt ccctgtctca gctagatccg taagtgtctg
    33001 ggcagtcaat accatctaat agctcataat aaccaagcta ggtccaagcg gatttggctt
    33061 ttttgtattc acaaaaagac ctacccaaat ggatagatct ttacttgatt acaatttacc
    33121 tgctactgca tccaacaatt cttggatctt aggttggttg cttcctcctg ccatggccat
    33181 gtctggttta ccaccaccac gtccatcgat gattggtgct aattctttga caaggtttcc
    33241 tgcatgaagg tcttttgtct tgcttgctac aaggacattg actttgtcac cgatagcggc
    33301 aactaggaca agaagatcag agtagtcttt ttgtttccag ttatctgcaa aggtacgaag
    33361 ggcacctgca tcggatacag acacttgact agcaatgtaa cgatgaccgt tgacttcctt
    33421 aacatctttg aagatatcgc ctgcggctgc agctgcggct ttttctttca actcagcatt
    33481 ttctttttga agttgacgaa gttgttcttg aagtccttct accttgtgag gtacttcctt
    33541 gacttgaggt gctttcaagg ttgctgcgac agctttaaga gcatcctctt gttcacgata
    33601 ggcttcaaag gcttccttac cagtcactgc caagatacgg cgagttcctg aaccgattcc
    33661 ttcttctttg acaattttga agagaccaat ctcagaagtg ttgccaacat gagtaccacc
    33721 acaaagttca atagagtagt caccgatagt cacgacacga acttccttgc cgtatttctc
    33781 accaaagagg gccatagctc ccatttcttt agcagtgtca atatccgttt caactgtctt
    33841 cacttcaagt gcttcccaaa ttttctcgtt aacttgctgt tcaatcgcac gaagttcctc
    33901 agcagttact gcttggaagt gggtaaagtc aaagcgaagg aattcaactt cgttaagaga
    33961 tcctgcctgt gttgcgtggt ttccaaggat attgtgaagg gcagcgtgaa gcaaatgagt
    34021 cgcagtgtgg tttttcatga cacggtgacg gcgattgcta tcaattgcca aggtatattc
    34081 ttggttcaag gcaagcggtg caaggacttc aactgtatga agggcttgac catttggggc
    34141 tttctgaaca ttggtcacag tagccacaat cttacctgac tcatccaaga tttgtccgta
    34201 gtcagctacc tgtccaccca tttcagcata aaatgacgtt tccgcaaaga taagagaggc
    34261 agttccttct gaaacagctc ctacttctgc attgtcagca acgatagcta ccaatttaga
    34321 agacaattgg ctagtattgt agttgaagac actttctaca gtgatgtttt gaagagtttc
    34381 attttgcata cccattgagc cacccttgac agctgacgca cgcgcgcgtt cttgctgttc
    34441 tttcatggct gcttcaaaac cttcacggtc tacagtcata ccagcttctt cagcgatttc
    34501 ttcagtcaat tcaactggga acccataagt atcatagagt ttaaagacat cttgaccagc
    34561 aatgacagat tgaccttttt ctttcaagtc tgccacaatg ccttgggcaa agtgttgacc
    34621 tgagtgaagg gtacgggcaa atgattcttc ttcgctctta acgattttct caataaagtc
    34681 acgtttctca agcacttctg ggtagtagct ttccatgatt tttccaacag ttggaaccaa
    34741 tttgtaaagg aaaggctcgt tgatacccaa tttttgacca tgcatagaag cacgacggag
    34801 aagacgacga agaacataac cacgaccttc atttcctgga agggcaccat caccgatagc
    34861 aaatgaaaga gaacgaatgt ggtctgcgat aaccttgaag ctcatgttgt cgccatcttg
    34921 gtcataaacc ttaccagaca atttctcgac ttcacggata atcggcatga agaggtccgt
    34981 ttcaaagttg gtcttagccc cttggataac ggccaccaaa cgctccaaac cagcgcccgt
    35041 atcaatgttc ttatgtggca attccttgta ttcgctacga ggaacagcag ggtctgcgtt
    35101 aaattgtgac aaaacgatgt tccagatttc aatataacgg tcgttttcaa tatcttctgc
    35161 aagcaggcga agaccgatat tttctgggtc aaaggcttcc ccacggtcaa agaagatttc
    35221 tgtatctggt ccagaaggtc ccgcaccgat ttcccagaag ttgtcctcaa ttggaatcaa
    35281 gtgacttgga tccactccca cttcaatcca gcggttgtaa gaatctttat cgtctggata
    35341 gtaggtcatg taaagttttt cagcagggaa atcaaaccat tcagggcttg tcaaaagctc
    35401 ataagcccaa gtgatagctt cgtcacggaa gtaatccccg atagagaagt tccccagcat
    35461 ttcaaacatg gtatggtgac gcgcagtctt ccctacgttt tcgatgtcgt tggtacggat
    35521 agccttttgg gcattggtaa tacgtggatt ttcagggata atggtcccgt caaagtattt
    35581 cttaagggtt gctaccccag agttgatcca caaaagagtt gggtcattta caggaaccaa
    35641 acttactgat ggttctactg agtgaccttt ggtcgcccag aaatcaagcc acatttggcg
    35701 tacttgtgca ctagatagtt gtttcatatt gtctccttat tcacttgttt aatgtgattg
    35761 gctttccagc atttccacat agtcaatcgc gacacagagg gaaatgacta ggtctgcata
    35821 agcgtcttca agaaccgtta cggtataggt agaggtcaga tggaagagtt ccttcttaat
    35881 ttccgcaatc aactgatcgc gatcatccag caatttgaaa ttcaaatccc agatattgcc
    35941 ctcgatacga agacctagat tatcaaactc atacttatct cgccagaagg tcaacttctt
    36001 acgaatgaca aaactcgagc catcccgaag ctgaatctca aaacgaggaa gcaaggtcaa
    36061 gatttcttta ctgatctgac tgacttgttc accagccgca tcatagatgg taaaagtttt
    36121 gggaatctta aaaaatgatc cctccacctg ataggcaatt tctcccctgt catccttgat
    36181 agcgaagcgt tcgcctccaa gacgaaactt ttgtttgaca agaaatgttt tcatcaacac
    36241 ctccaaaaat caaaagacaa gctcatatca cgaagggcga aaaaccgcgg taccaccttc
    36301 attcaatgaa cttgtcattc tcttgttctt atgcaattgt atgattgagt agcatgactt
    36361 cctagcttag atggctcgca gcaccgccat ttctctggac taagacaagt gaaaatcaat
    36421 tctcaacttt cttattataa cgttttttta agcttgcgtc aactggaaat gatctccgtt
    36481 gaattagacc aattccctac atctctgatt actttttcag gatatatttt ttcttactgc
    36541 catttttctt tttatcccaa attttcatat tactaaacac agctactaga atatttccaa
    36601 atataaaggt gcctatcacc caatatatgg actcagttgt taggtattgt cgatccaagc
    36661 catcatttaa atggaatagt atagcagttt ggttaacaat cataaaggtt ggccagaaac
    36721 tttttttgaa aaaagtagac attttcatta tttgttgccg ctttctgtaa ggttaatact
    36781 caataaaaat caaaaagcaa actaggaagc tagcctcaag ctgtacttga gtacggcaag
    36841 gcaacgctga catggtttga agagtatagg cttagtatac tactaggcaa gcaaataagc
    36901 aaataagcaa ataagcaaat aaacaactag aatagaaaaa gatagggctc taaaaactga
    36961 cttctattcc ttaaaaacga accagcttga ctgattcgtc ttcttacgtt tatctcctac
    37021 ttccgataca ttttaaactg taggaagagg tcgctatatt tccctgtcca tttatggtca
    37081 aatttctcat aaacttctag gtgtttcatg gtttcaacat cgggatagaa ggccttatct
    37141 tcctttgttt cctctgggag caattccttc gctggtaggt ttggtgttga atagccgaca
    37201 tactccgcat tttggagagc attttcaggt ttcaacataa agttgataaa ggcataggct
    37261 gagttttggt ttttaactgt tttgggaatg accatattgt caaaccaaag attgctggcc
    37321 tctgtcggta ccacataacg tagattttca tttttttcta acatttggct ggcttcacca
    37381 gagaaggtca cgccgattgc aacattattc tgaatcatat agcccttcat ctcgtccgca
    37441 acgatagcct tgatatttgg agtcagtttg tagagcttat ccactgtctc ttccaactgc
    37501 tgcagatcct tggagttgag gctgtagccg agggaattga gtcctagtcc cagcacctca
    37561 cgcgccccat caaagagcat gatagaattc ttatactccg gcttccaaag gtcatcccaa
    37621 tgctcaggcg cttcatctac catggtttcg ttgtagacaa ttcctaaggt tccccagaag
    37681 taagggatgg agaatttatt acctgggtca aaggactggt tgagaaactc tgatccgata
    37741 ttttcgattc cttcaatttt tgaataatca agcggaacca agaggtcttc gtccttcatc
    37801 ttgttaatca tgtattcact tggaatggca atatcgtagg tcgttccacc ctgctttatc
    37861 ttagtgtaca tggcttcgtt ggagtcaaaa gtctcgtact gaacttgaat tcctgtttct
    37921 tctgtaaact gagtcaagag ttcaggatcg atatagtctc cccagttata gataaccaat
    37981 ttttgactat ctcgactatt gattttacta tctaaatgag tcgcaattcc ccacaagaca
    38041 aggataatcg ctgcaattcc tgctaaaaat gaatagattt ttttcatgct tgctcctcct
    38101 tctcacgaga gataaagtaa taacctacaa ctaggataat actaaagaga aagactagag
    38161 cagacagggc attgatttct aaggaaatcc ccttgcgagc acgagagtaa atctcgactg
    38221 atagggttga aaagccattt cctgttacaa agaaggtcac ggcaaagtca tctaacgaat
    38281 aggtgaaggc catgaaataa ccagtaatga tagacggagt caggtaagga agcatgattt
    38341 ccttgaacat ctgaaattga ctagctccca agtcataggc cgcatgaatc atgtcgccat
    38401 tcatttcctt gagtcgaggc aagaccatca agaccacgat aggaatggag aaggccacgt
    38461 gactagatag aacggtcaaa aagccaagtg aaaacttgag ttgggtaaag agaatcaaga
    38521 agctagcacc aatcataacg tcaggcgcaa ccatgaggat attattgagt gatagaaagg
    38581 cttcttggta tttcttacga gactggtaga tgtaaatggc accaaaagtc ccgataatgg
    38641 tcgctatcaa ggctgatagg aaggccaaga aaaatgtctg agccaaaatc agcatgagtc
    38701 tcccatctcc aaacatggtt tcaaagtgag tccagctaaa acctgtaaag ctattcatat
    38761 catcaccagc attaaaggca tagccaatca agtaaaagat aggcaggtag aggaccagaa
    38821 agaccagtcc cagataaagg ttggcaaatt ttttcatcgt tctctccttt ccttagtcac
    38881 ccacatggtg atgaacatgg tcaggatgag aatcacaccg atggttgaac ccataccata
    38941 gttgtcattg gttagaaaat tctgctcaat agccgtcccc aaggtgataa cgcggttccc
    39001 accaatcaaa cgggtcagca tgaagagact caaacttggg ataaagaccg actgaacccc
    39061 acttcgcaca ccgttcatag atagagggaa gatgacatga cggaaggtct cccacttagt
    39121 tgcaccaagg tcataactag cattgatgag attattatcc atatcgtcta agacattgaa
    39181 aatcggcaaa atcataaagg ggagctcgat gtagcttgcg acaaagataa aggaaaaatc
    39241 ggtaaaaagc aactgttgtg aaccaattcc gataaattcc aagaattggt taatagagcc
    39301 attttgacca aaaatcccga taaaagcata ggctttaagg agcaaattga tccaggtagg
    39361 aaggataatc agcatgagcc agagttgacg gtgcttgaga cgggtcaaaa agagggctgt
    39421 tggatagctg ataagcaagg tcacaaaggt cacaatccct gcataaagca ctgagttgaa
    39481 actcattttg aggtaggtca agttttgtga cgcaaagtaa gatttataat tttctaaact
    39541 aaactggcct tcaatgttga aaaaggattg tccgaaaatc aagaccaagg gtgccaatac
    39601 aaagagggca atccaaagca tgtagggcac tacaaagagt ttagagcttg ttttcttcat
    39661 ctctttcctc ctcgatcgca ttgatcagac ctgcttcttg ctcttcgatt tccacgtatt
    39721 cttcgatacg agcatcgaac tcttcttcgg tttcattgag acgcatgatg tggatgtctt
    39781 ctgattcaaa gtccagaccg atttcctcac ccacgatggc cttacgggtt gagtggatca
    39841 tccattcatt tccaagttcg tcataggcga taatttcata atgaactcca cggaagagct
    39901 gggtgtcgac cttaacttgg agtttgcctt cttcaggaag ggtaatgcgc aagtcctctg
    39961 gacgaataac gacctcaaca ggttcatttg gcttcatccc accatcaacc gcttcaaagc
    40021 gtttgccgtt aaattcgacc aagtagtcct caatcatggt acctggcaag atgtttgact
    40081 ccccgataaa ggtggcaaca aagtggttga ttggctcatc gtagatgtcc acaggggttc
    40141 cagactggac aatctcgcca tcattcataa cgaaaatcca gtcactcatg gcaagagctt
    40201 cttcctgatc gtgagtgaca aagacaaagg taatgcccaa tcgttgttgt aattcacgca
    40261 attcgtactg catgtctgtt ctcaatttca agtccagcgc tgataaaggc tcgtccaaca
    40321 agaccacacg gggttggttg atgatagcac gggcgatggc cacacgctga cgttgtcctc
    40381 cagaaagttt gcggatggaa cgtttttcat aaccttccaa ctgaaccatc ttgagaactt
    40441 ccgctacgcg ttgctcgatt tctttcttgt caatcttgcg caagcgaagt ggaaaggcaa
    40501 cattttcaaa cacattcata tgtgggaaca aggcatagga ttggaagaca gtatgtacgt
    40561 cgcgcttgtt ggttggaata tcattgatac gaacaccgtc tagcatgata tctcctgtcg
    40621 tcgcatccag taaacctgca ataatgttta ggatagttga tttccccgaa ccagatgcac
    40681 ctagaagggt gtagaatttc ccttcttcca actcaaagtt gatgtctttg agaaccttgg
    40741 tgttgctgtc ttcaaaaact ttagagacgt ttttgaattc gataattggt tttttcaatt
    40801 ggcataaatt ccttcttttt catagattaa ccgatcgggg ctctgtcagg tccccactac
    40861 ctcttgcagg gagtaaaacc acctgcatac atcttcgcta ccgataggct ttcacccccc
    40921 tttccatgac atagcagcag cttttcaaat acagcttcct acttgctttc acccaagatc
    40981 cggacttctc tttcaagcgt aatacctgag tgttccttga ctttttcgat aaccgattgg
    41041 atcaagtcct cgtagtcttt ggccgttcca tctgcgacat tgatcataaa tcctgcatgc
    41101 ttttctgaca cttctacgcc accgatacga tagcctttca agccagcttc tgaaattaac
    41161 tgacctgcaa aatgcccgac tggacgctta aagaccgagc cacaagatgg gtattccaaa
    41221 ggttgcttga gttcacgtag gtgcgtcaag cggtccattt cctgcttgat aacctgatgg
    41281 gttcctgggg ctagggcaaa tttaactgac aagacaactg caccagactc ctgaatagct
    41341 gaatggcggt aaccaaaagc caagtcttta gcagacaggg tttcgatttc tccatccttg
    41401 gtcaagacct tacaagactg caatatgtga gcaatctcgc caccataggc acccgcattc
    41461 ataaagacag caccgccaac gcttcctgga ataccacaag caaactcaaa gccagtcaaa
    41521 ctatgacgga gggcaatgcg agttgtttca atcaagttag ccccagcttc tgcttcaatg
    41581 gtatagccat caacagaaac gttattgagc ttgtcacaca agatgacaaa tccacgaatc
    41641 ccaccatcac gaacgatgat attgcttgca ttgccaagaa ccatccaagg gatattttct
    41701 tggttggcaa atttcacaag gcgagccaac tcaaaacgat ttcgtggaaa gaccaaataa
    41761 tcagcctctc cacctacttt tgtataacta tagctatgca agggttcctg aaaacggata
    41821 tcaattcctt ctaagatttc aagcattttt tctcttacag acatgtcact cttcctttta
    41881 caaaattcat tccattatac catttttaga gacatttgac gaccataaaa ataccttgtt
    41941 tggattttgc ataagaaaaa gaggttcccc tctttttatg attttttaca aaagatttcc
    42001 ttggttccat aggcgaccag aacgagctcc agtgctagaa tcacttcaac caagactgga
    42061 tttgtcaacc agcctacttg gaaaagagat ggtgccagat caaagaaggc atgcaagcca
    42121 taggctgtta ggagataaat ccatttcttc tggcgaacag cttgataaac ccaaactgtc
    42181 aaaagtaatt ggaaaccaag cgccaagatt cgctcaaaac caagcaaata aatctgccag
    42241 accgaaagtg actgaatggt ttttaacata ttttcagaca gtaattgcat aacctgtgga
    42301 ttctgagttt gaactgccga aagaacaatg taaagattga gtaaactagt aaggcctaga
    42361 aaaatcaact ccaagccacc atgccccaat ccataggcca aggcgtctgc cttttccaaa
    42421 cttctctttt tctccaacca tttgaagaaa acaagacgag ccgtttcctc aaaaaatgct
    42481 accatggcta ggccatagat aatatagata agcggatgaa cttacaagag ggcaatacta
    42541 ccgtcttttt gaggatgcaa aatcaagata tgcaccagtt tttccaaaat ctgcgaagag
    42601 acaaagaaag cgactgcacc caagtccaag acagctagat taatctggta tttctttttg
    42661 gcaaaccaaa tgcttcctat cagaaaagct agcaacagca acatggtaat aatgatatga
    42721 atggtcattt tcttctccta ttctgccttt tcaatatctt ttttcatctc gtcaacattg
    42781 aacttagcaa acaagtattg acggtcttgg actgggaaac gttggtccaa ctggtcaact
    42841 gctcccacct cgataatgcc ttccttgatg acaaaatcca tgacatgtcc accgaaggtc
    42901 aaatcatctg atatgaagtg cagatggtag cctgccacac tgaccccatg gaaaatctca
    42961 ggcgtccaga aaccaacaat agtccccgca acattgtcac gactatattc cggttgatgg
    43021 gttgcgacat cagcaaactt ggtatcgggt gttgacttag gaatcatacg cacatgcata
    43081 tgtgaaaatt ccccccgaat cttgatagag cggaaaagat tttccccatc ataataagac
    43141 tcaattcgtt ctttcaattc cttgtctgtc atctcaaagc gctggcggaa aatgacctct
    43201 gcctgatgcg gtaccactgc agcgtaagga ataagggcat ctggtgacac ttccacaatt
    43261 tctggctggt ctcctgaccc tttggcctga taagccttgc catccaagac aatcaattcc
    43321 ccatcaatgg aatccaaggt tcccaaacca aggtcaccat gttctagcaa ttctcctact
    43381 gtcatagtac caccataaag gccagccatc aaggctccaa gagtattgta ttgaaataat
    43441 ttcactggtt cctgcacgtt cttatccatt cactttcttg tctgttattc tataaatctt
    43501 actcctaagt ataccacatt tgcccctaga tgtgaacgag agaaacgctc tagacattgc
    43561 caagaaggaa aaacagggta caatgtaaca aaatcaaggg aggtctggaa tgaagaaaca
    43621 aagcaagtac aaagaggtcg tttcctatct gaaaaatggt atcgagtctg gacgatttcc
    43681 gacgggtagc ctgagatttt gacagaaaca aaacttgcac tagcacaaca acccctaagg
    43741 aacacacttc cctaggggtc gctttttatt taactaaatc attatttatt ttttgttcct
    43801 agtaaacata aatattgtat taataattgc aaaaataaat gcaaacaaaa ggattttcca
    43861 aaggataaat ttttgtaaca ctaaatatgc atatacaaat ccaatcaaaa agctaataat
    43921 cccatctttt attaaaaagt ttttatcacg cattattcca gaccacactg aactgcccaa
    43981 atagccaact gaccagcaat gatataaata tttgttttaa gtccattagc tttaacaaat
    44041 cttagtacca ctttagctaa ttctgaccaa gcctttttct gcgcatactt aacaattagc
    44101 gaaacattga tcatagcaaa aaattcatct cgtatttttc ctgctataca tcctcccatc
    44161 tcatcccaag ggactctgtc atagggatta ttaatattag tttctaattc attttccgca
    44221 agagcaatat ctttttgaga aaagttttta taaacatatt cagtaaaatt tttttcatta
    44281 actccatttc taaacatttg ttcaagaaca ttggctacat catcgatttg tttttgttct
    44341 tgggtactaa tttcagaaac ttccgtagta gttacatcat cagcaaatac tctaacagaa
    44401 gctatagaag gagacataat agaaaatagt gataatacaa caagagctga agttacaatt
    44461 tttttaaatt tcataaaaaa cactcctttc aagtcacaaa tatatattac tgataaaata
    44521 acttgatttt ctgatttaaa actcctttct aacaagttat tcgtatgctt ttatttttta
    44581 gttctattat accacaacaa gaaaacgatt tcaagcattt tcctaaaaat atgtacaagt
    44641 aatatgtaca agtaataagg ggaaattagc ataaaaactt tttaaaacaa atcaacccca
    44701 gataaaaata cacatgttgt tttaaagaca aaaaagggta cgaaaaactg tcacatctgc
    44761 atttgattgc tctttgattt caaaaaagta ttaaaaatgg gagtatacca catttgcccc
    44821 tagatgtgaa cgagagaaac gctctagaca ttgccaagaa ggaaaaaaaa gggtacaatg
    44881 taacaaaatc aagggaggtc tggaatgaag aaacaaagca agtacaaaga ggtcgtttcc
    44941 tatctgaaaa atggtatcga gtctggacga tttccgacgg gtagtcgcct gccttctatc
    45001 cgtcaactga gccttgactt tcactgcagc aaggacacca ttcaacgagc cctgctggaa
    45061 ttacggcacg aacaatatct ctatgccaag cctcagagtg gctactatgt attagaacaa
    45121 gggcaacatc aagacctaga aatcgaggtt accgacgaac atgccagtgc ctatgacgat
    45181 ttccgactct gtgtcaatga aaccttgatt ggccgagaaa actacctctt caactactat
    45241 gacaatcaag aaggattaga agacctaaga cagtccattc acaaactcct ctttgagcaa
    45301 gctctctact gcaaggctaa ccaactagta ctgacttctg gaacccaaca agccttgttt
    45361 atcctctctc aaatatcctt tcctagacaa gccaaggaaa tcttggtgga acagccaacc
    45421 taccatcgga tgaatcgcct cttgattgca caggggctgg actatcaaac gattgaacga
    45481 ggcattgatg ggattgactt ggaggagctg gaaggccact tcaaaacagg aaaaattaaa
    45541 tttttctaca ccattcctag atttcactat cctctgggac attcctattc tgagcaggac
    45601 aaacgatcta ttcttaactt agctgccaag tatgatgtct atatcgtaga ggacgattat
    45661 ctgggtgatt tggactccaa gaagggccaa accttccact atcttgatac agaggagcgt
    45721 gtcatttata tcaagtcctt ctcgaccagc ctttttcctg cccttcgtat tacagcactc
    45781 attcttccaa atgctatcaa agaagcattt gtggcctaca aaaatatcct agactacgac
    45841 agcaacctca ttatgcaaaa ggccctgtca ctctatattg acagtcaatt gtttgaaaaa
    45901 aatcgtttgg ctcgcttgac caatcatgaa tcttaccaaa aacaaatcga ggaaaggata
    45961 actaaaacac cttgtcccct tcctcattat cccctacacg atggtttatt gctagacctg
    46021 agacagtatc ctaaaatcgc cagtctcaaa cacagtcaac tgggcttgga cttctttgaa
    46081 gaggcctatt taagcacctg tccttatcaa tttgccaagg tgtccctaga caatctggaa
    46141 aatgttttaa actatttaaa agcagaattg gaatgacatc caactctgct ttttcttatt
    46201 cttcaacttc agttaaactt gctgcttttt caagatagct ttggtaagtt ccttcatcct
    46261 taagtttttg gatgaccttg tctaccactt ctttcaaatc atcactattt tttctaagag
    46321 caacggcatt ggcgtcgccg tccttcatct tcaagctgac agttgcgaca gctaagccag
    46381 cgtttttagc agcataacta agtgcaacag gctcatccat atgaacagca tctacttttc
    46441 cagcctgcaa ttcattgact gcttcaccca tattagttag ggaagttaat tgagcttttg
    46501 gcaattgttc cttgaccatt gattctggaa cagtcccttt ttgggctgca atattagcac
    46561 tttctaggct agttaaatcc ttgtattttt ccacatcagc cttacgaacc aagaaactaa
    46621 tcttgttttc atagtatggg attgaaaaat caaagacttc ttttctctcg tcagtagcac
    46681 taattcctgc aactgctagg tcagccttac cagtttgaag actggtcaaa acattatcaa
    46741 aactcatgct tgagatttcc aacttaaccc caagttcatc agcgatagcc tgagccatgt
    46801 cgatgtctgc accgactacc tggttctttc catcaaccaa tgattgaaat tcaaagggtg
    46861 catagtcagg actggttgcc acaactaatt tccccttttg cttaatggcc tcaacagctg
    46921 actgagaacc attagaacct gactggcaag ctactaagaa gaaacttgca agaaaattac
    46981 ataaaacaaa tatccatttt tttgatttca taaataaaca acctctctgt taattttgta
    47041 taattataac gatatccaag ttacttgtca agtgtttttt aaatttttat ctcaaaaata
    47101 ttttttcgtt caaaaaaagg agccatcagt tgatttcaag ctccttttta tacagaatta
    47161 aactatttta tagttcgaca atcttacctg tttcaaagta gacaacccat tcacagatat
    47221 ttttagcata gtcaccgata cgctccaagt aggaaataac ttggaaataa tcacgacccg
    47281 taacaatggc ttctggattt ttcttaatct cttcagtcgc aaggtcacgg atagtttcaa
    47341 aatagtggtt aatttgctca tccatggagg ccacccggta tgcgtcgtca acagaaccat
    47401 taagataaag atcaagtgct gcttcaacaa cgcttttaac ttcacgtccc atttttttaa
    47461 tttcttcctc tacagctgga atgcgctctt cccccttcat acggatggtt gcctgagcaa
    47521 tggctacagc gtgatccccc atacgctcca catctgatac agccttaagg acagtcaaga
    47581 ctgtacgcaa atcttgagag actggttgtt ggagtgcgat catttcaaat gatttctttt
    47641 ccagtttcac ttcgtattca tttacttctg catcatcttc gatgacctct tttgccaggt
    47701 cacggtcatg cgtgacaaaa gcacgtaccg tacgattgat ttgtgagagc acttcttgtc
    47761 ccatagcgta gaactggtta tgtaatttct ctaaatcttc ttcaaattga gatcgtaaca
    47821 tctttcatct ccttatccaa attttcctgt aatatagtct tccgtttcct tgtgttgggg
    47881 attaaggaac atctgcttgg tatcattaaa ttcaatcaaa tctccatcta ggaaaaatcc
    47941 tgtcttatca gagatacgtg aagcttgctg catggaacgg gttaccagaa gcatggtgta
    48001 cttgtctttt agaccataca aggtttcctc aattttacca gctgaaatcg gatccaaagc
    48061 cgaagttggc tcatccaaga ggatgatttt aggactagtt gccaagacac gggccacgca
    48121 gacacgctgc tgttgaccac ctgacaatcc aatagctgaa tcatatagac gatccttgac
    48181 ctcatcccag atagaggcac cttgcaaggc tttttctacg gcttcatcca gaacctgctt
    48241 atccttaatt ccattgatac gaagcccgta gacaacattc tcatagatag tcatagggaa
    48301 aggattaggt tgttggaaaa ccattccgat ttccttacgt aattcaaccg tatctgtacg
    48361 cggactgtag atgttgtgac cattgtacac cacggatcca gttgtggtca cctctggatt
    48421 gagatctccc atgcggttga gagacttgag gagggttgac ttccctgatc cagatggacc
    48481 aatcaaggct gtaatttcct taggttggaa agatagggaa acactattca aagccttctt
    48541 tttattataa taaacggaca ggtctgatac ctgtaaaatc gcatctgtca tacggtttcc
    48601 tttctaacca aagtgaccag atacatagtc attggtggac tgtagcttgg cattttggaa
    48661 aatagttgca gtcttgtcat actcaatcaa atcacccaag taaaagaagc ctgtatagtc
    48721 acttgcacga gcagcctgct gcatattatg cgttacaatg atgatggtaa agtttttctt
    48781 gagctcaaac atggtctctt ctagttgcat ggtcgcaatc ggatccaagg ctgaggctgg
    48841 ctcatccatt aagaggatat ctggcttaac agagatggca cgagcgatac agagacgttg
    48901 ttgctgacca cctgataagg tcaaggctga cttgtggaga tcgtctttaa cctgatccca
    48961 aagggcagcc tgacgaaggg aggtttctac gatttcatct aggacttgct tatccttaac
    49021 tccagcacgt tcatgcgcaa aggtaatatt acggtaaatt gacttagcaa atggattggg
    49081 gcgttgaaaa accattccaa tgtgtttacg catttcataa acgttgattt ctggacggtt
    49141 gacatcaatt ccacgataga gaatctgccc agttacttta gcaatatcaa tggtatcatt
    49201 catgcgattg agactgcgta agtaggtaga tttccccgat cccgacggac caatcaaagc
    49261 tgtaatttta tttctttcaa attgcatatc aatcccctta atggattcat ttttaccata
    49321 gtaaacatgg acatccttag tagaaagggc tactttttct tcaggaaagg taaggatatg
    49381 cttctcatcc cagttatatg ttgacatggc ttctccttta ggcagcggtt aatttcttgt
    49441 gtagatagct tccgaactta cgagctccaa agttaaaaat caggataaag atcaggagca
    49501 cagcggcaga acctgctgat acaatggttc catctggaat agtgccttca ctattgactt
    49561 tccagatatg gacagccaag gtttctgctt gacggaagat agagatgggg ctagtcacac
    49621 tgaggatatt ccagttagac cagtcaagag ctggcgccga ttgccctgct gtatagatca
    49681 gagctgcagc ttcgccaaag atacgaccag atgccaaaac gacacccgtt acaatacctg
    49741 gaagcgcttc tggaataaca acatgaacca ctgtctccca gcgagaaatc ccaagagcca
    49801 gaccagcctc acgttgggta tggtgaacgt gtttcaaact atcctctaca ttacgcgtca
    49861 tctgaggcaa gttaaagact gtcaaggcca aggcacctga aatgattgaa aatccatact
    49921 caaactggac tacaaagatc aagtaaccaa agagacccac caccactgat ggtaaagagg
    49981 acaagatttc aatacaagtc cgcacaaagt tggtaacagg acctttttta gcatattcag
    50041 ccaagtaaat cccagctccc atagaaagag gtacagaaat aatcaaggta atgaccaata
    50101 ggaaaaagga attgtaaagc tgaatgccaa tcccaccacc tgcttgaaaa gcagaagacc
    50161 ttccagtcaa gaaagaccaa gagatatggg gcaagccccg aaccaagata tagagaatca
    50221 aggaagccaa gattgtcaca atgatgctag caatcgtata gaggacagct gttgcaagtt
    50281 tatctaattt cttagcgcgc ataatttttc tttcctcttt ctttcgtaat caatttaatc
    50341 acactgttaa aaactaaact catcaagagc agtaccaagg ccagtgacca gagaacatta
    50401 ttatttacag ttcccatgac agtgttccca attcccatag ttaatataga agttaaagtt
    50461 gcagctggtg tggtcaagga agttgggata acagctgagt ttccgacaac catctggata
    50521 gctagagcct caccaaaggc acgcgccatc ccaaagacca ctgcagtgaa aataccagaa
    50581 cgggccgcct tcaagatcac acgccagata gtctgccagc gagtggctcc catagcgaaa
    50641 ctggcttcac gataataacg aggaaccgca cgcaagctat ccgttgtcat aaaggttacg
    50701 gtcggcaaaa tcatgacaaa gaggacggaa atccctgaca aaatcccaaa accagtccca
    50761 ccaaagacac tgcgaacaaa gggaacgacg acttgcaagc caataaatcc gtacactact
    50821 gaaggaatcc caaccaggag ttcaatagct ggttgcaaaa tcttcgcccc ttttggtgat
    50881 acttcggtca taaaaactgc tgcaccaata gcaaagggtg ttgcgataag ggctgagaga
    50941 atggtaacga taaaggaacc caaaatcata ggaagggcac caaattcttt actagaagga
    51001 ttccaagttc ctcccaaaag aaagtcaaag atattcacac cattgacaaa gaaggtcgac
    51061 aagccttttt gcgctacgaa aaccaaaatc atggccacaa ggatgactat caaagaaaga
    51121 caggcaaagg tcaaaccttt tcctaatttc tccagacgag aattctttga tggaagcaac
    51181 attttcttag ctaattcttc ttgattcatt attgtctccc ttccaacact gtcacagttc
    51241 cggcagcatc tttttcaacc ttcatttcct taatcggaat atacttcaat cctttgacaa
    51301 tcccttcttg ggtctcatcc gagagaacaa aattgagaaa ttctgcagcc aactcattgg
    51361 gctgccccaa tgtatacata tgctcataag accacaaggg ccaattattg ctacttatat
    51421 tttctggact taagtcatag ccattcaact tcatgctttt gaccgaatca tctatatagg
    51481 taagagataa ataagagata gctcctggac tttttgatac gattgatttt accgctccat
    51541 ttgaatcctg ctcctgactt tgcatggcag actgaccttc cataatgaca gtatcaaagg
    51601 tagcacgaga gccagagccg gctgcccgat tgataacaga gatgggtaag tccttaccac
    51661 caacctcttt ccaattggtt acctcaccta tgaagatttg acgaagttgc tctgtcgtta
    51721 ggttatcaac atcaacctcc ttattgacaa tcagagccaa gccagctacc gcgaccttgt
    51781 ggtcaacaag agcagaagca tcaattccgt ctttttcctc agcaaataca tctgagtttc
    51841 ctatatcaac tgccccagac tgaacctggg acaagcctgt accagaacct cccccttgga
    51901 cattgaccgt ttttccaaca tggatcgtgc caaattcatc tgccgctact tcaaccaagg
    51961 gttgcaaggc agttgagcca acagccgtta tggattctcc acgatcaatc cagctagcac
    52021 agcctactaa acaagccgtc agccaaaaag cgataagaga cagagcaagc ttttttcttt
    52081 ttttcactgt ttttctcctc gaaaataatt atgaatactg tgaatttttt aagtagttct
    52141 ttatgagttg acgcatgaat tcttaccaaa tttctgcgca attgattatt tatataatat
    52201 aggctatatt actctttcct aacctccttt tttcatatgt ggataaaatc tcttgtctat
    52261 cccttccccc attgtcaccc attatagtca tttcgtgtct ctttttcccc tttttaatgc
    52321 aagggaaatt actcttctta gatgataatc caaaagctag aaaggtatct caaacctctc
    52381 tactctccca gactagttta caactaaaag gaaaagattc tattttatga gaaatctagt
    52441 ttacaagcgg taagaacgct aataactaaa cttcttgtac tctttgaaaa tctcttcaaa
    52501 gcagtgtttt gagctatcta tggctagctt cctagtttgc tctttgattt tcatcgagta
    52561 gtaaaactac atgtgatggc aatcaagata tcaagaatca tcctactaaa aaaatccata
    52621 ctttcactat aacatagaat aagatatttg actagcattt tcatttgaat ctgaggcctt
    52681 ttggaaaata atttttcaaa acatttccag taacctttgc aaagcccaag ccattgcctt
    52741 taaccaaaac ttggtaccaa ccatttggca gactttctgc cagctgaacg gtttctccag
    52801 ccgcatactt gacaaacgct tcttggccaa tttcaaccga ctgttcgacc tgactcggtt
    52861 tcaaggctaa accaagagcg aaactgggct caaagcgttt cttcttaaaa gtacccagat
    52921 gcagtccatt gcgagcaatc ttgagcttcc ctaaatctgg caaaagttct ggcaagagat
    52981 aaagctggtc tccaaaaatc tgcaagatac ccggtagatt gaccttcaaa tggttttggg
    53041 caaattcctg ccacaaggca acttgttcac ggctgaggtt actcttactt gccttaaatt
    53101 taggagctgg attgttaccc ttaaactgta gatgggcaac aaactgaccc tctcccttaa
    53161 actgatgagg gtacatccga gccgtttctg gcaggtcaat accagctacc attccattga
    53221 tatgctctac tggcaacaag tcaaaatcat actcttccag caaccaattg acaatctctt
    53281 cgttttcctc gggtgcccag gtacaggtcg aataaaccag acgaccacct tcagctaaca
    53341 tggtcactgc atcctccaga atttctcttt gcaagctagc acattgactc ggataatcta
    53401 agctccaata gtccatagca tcaggttgct tacgaaacat tccttcacca gagcaagggg
    53461 catcaagaac gattaagtca aaatagcctt taaagacctt gaccaagcgg tcggcagatt
    53521 cattggtcac cacgacattt gtcgctccaa aacgctccat gttttcaacc aaaatcttag
    53581 cccgtttgct tgaaatttca ttggaaacaa gtagcccctc ccctgctaga taggctgcca
    53641 gttgagttga tttgcccccc ggtgcagcag ccaagtccaa gaccttcata ccaggactgg
    53701 gttgggctac ttgagccacc atttgagcag caggttcttg cgaataaact aaacctgtag
    53761 catgctcagg cgatttccct gaaaccttcc catagtggcc ccaaggggtt tgagtaatgg
    53821 catcagaaaa ggaaagttgc tcttctttta agggattgac ccgaaaggcc gaaaccgctt
    53881 cctcctcaaa agaggcaaga aaatctcttg cctcatctcc tagtatttct ttatattttt
    53941 caacaaatcc ttctggaaat ttcatttaag ttcttttcct ttcgtaaata taggactgaa
    54001 tttcctcctg catctcaaga ggcaccatca tgaccggctg tctggtttga aaatcaggag
    54061 cttcaccaaa aagggtcaca acccgatagc ccagactttc ccctaaaata ctagctgcgg
    54121 cataatccca tggttgcaga taggtgagat aggtcaacaa atgccctgac aaaatcttgg
    54181 caaaactaat ggccgcactt ccatagacac gaacaccaag aaccgctcgg ctcaaatcag
    54241 ccagccccca ttcattggtt tccagcatac cactattccc tgcaatgaga aaatctccaa
    54301 gtggtttagt tttaaaagga gctaggggcc tatcatttag acaaactgga aattccccac
    54361 caccgtggta acaatcccct ttgaccacat cataaatcag accaaactgt ccctgaccat
    54421 tttcaaaata agccatcata acagcaaaat cttcctgctg ggctacaaaa ttattggtac
    54481 catcaatggg atcaatgacc caaaccttgc cctcttgaac cgaggctcgc agacaacctt
    54541 cttcagcaca aatcttatcc tcaggataac gggacaaaat ctcaccaacc aagagttcct
    54601 gaacttcttt gtccagtctg gtcaccaaat ctgttggaga ggacttggtt tcaacacgca
    54661 agtcttcctg catatggtca agaatgtact ggcctgcttt cttaacaagc tctttagcaa
    54721 attcaaattt actttccaag agaaatcttt ccttcccctt tttctttggc agcctgaact
    54781 gctcggtaaa gtgaatagcc actaaccgtt tcaaattctc gtcccaaacg tttctcttcg
    54841 ctcttgcttg gcacgaccgc tttgaatccc ttataggagt ccagtaactt tttagcctct
    54901 actttgcctt cataggcagc ttcaacatca ttaaaaaaag aaagcactga agcaagttct
    54961 tcagtgctcc acgacaaatc tagtgggtaa ctatactgtt tgttcattaa ctaataccag
    55021 ctctcattct tgcttctttt agttcttgct tacgataact acgagggaga aaagcacgaa
    55081 tctcatcttc attaaaaccg atttgcatac gcttggcatc aataataatt ggacgacgca
    55141 aaagactagg atactgctca atcaaatgaa gcaattccga taccgaaata ctctctacat
    55201 caatattcaa tttttgaaaa atttttgaac gagttgaaat gatgtcatca gtaccatttt
    55261 cggtcaagga aaggatgtgt tgcaattctt ttcttgttaa aggactggtc ataatattgt
    55321 gttccacaaa gggaacctta tgtttttcta accaggcctt agccttacga catgatgtac
    55381 agctcggtga tagaaatagt gtaatcatgc ttttctcttc ttatctatac tttgctactt
    55441 ctattataca aaaaaataaa gcgcttgact agggattttt agaaaaaaag cctatttttt
    55501 caagaaaaat aggctttttg cgaacgattg acacaattgg atttggttaa ttcactctta
    55561 acgatggttt taaacgatat atatttttat atatgtaaat taaaaacatc tttcctttca
    55621 cttcctacga cttttcagat acagatagcc aaagaagttt tcatagaggg caaaaaagag
    55681 gaggaaggca tgaagaaaga aggtctctgg caaaatcata ataacaggat ccttggctgg
    55741 atcaaaaagc caggtatcat ctcccacaaa gagaatttga tggaaaagag taaagaattg
    55801 gtcaaaacca atcaaaactc ccccaagtcc aatcatcaca ggtaagacta ctagagccag
    55861 gagacttttt cgataaagag acaaaaagtc ctttttcaca atcctattga caaagacata
    55921 gaaacttggc agtgtcacta gagctactag ctgaaccaaa tgaaagagat tcttgaccac
    55981 tgcgaaatgg tgcagaccag ctgctgacga acgaaaatca ggcatctgta agacctgact
    56041 aaaaggattg gtcagataat tcatcaagat atgaaaattg tattgaatgg tttctggttt
    56101 tagatagact cgattcgtta agtttagcca ctgaatctcc ataggataga aaatccaagc
    56161 cagataaatg gtcagaagga ttgagaggga gaggagaaag agcatagagc cccaaaaggt
    56221 caatttagtt ttcatcaaaa tcccactccg caaggctaga aaccacatgt gtcggtgcga
    56281 ttggcaggcc agctacttct tctgccttag taaaacctgt cgtcaccaag agcgttggaa
    56341 tgccattgtc aatcccagcc cggatatcag tcaaataatt gtccccaacc atgattaact
    56401 cttcacgttc caaacctaag tgctcaaccg ccttgtccat aatgatggca tttggttttc
    56461 cgatataaac cggcttcact cgtgtcgcta cttcaagcag cgtaatcagt gagccagcac
    56521 ctggcaaaag accacgttcc gtcgggatgt tgaggtcagg attggttccg ataaaatggg
    56581 cacccttttg aatagcaaga gttgctgtgg caaatttttc atagtcgact tgccaatcca
    56641 gaccaactac cacgtaggca gggttttcct tgtcttccac ataaccagcc gccttgatgg
    56701 cttccttgag tcctgcttct ccgacgacat agacagtctt ttcaagcccc aaatcattca
    56761 tatagtcgat ggttgccaaa gtcgctgtgt agacagtcga tagaggcgta tcgatattaa
    56821 aattctgagc caacatctcc ttaacactct ctggagtgcg ggttgtattg ttggttacaa
    56881 agagataggg aatgtcccgc ttttgcaatt catgaacaaa agtctctcca gcagggattc
    56941 ggtctttccc cttataaatg gttccgtcta aatcaattaa atagccttta tatttcatct
    57001 atttctccct aaaccttttt tatttcttgc caagtaatga ttgcttgggc attgataacc
    57061 ccatcacttg taatttcatg cttgctttcc agtccagtcc gttcaacagc cgatgtaatc
    57121 accccacctg gtcgaacttc cttgacatac ttgaggttga ttttcttggg aatatagtgg
    57181 gtcaaaaaat ccgctcccat gacctcaaaa atccagtcca agtatttact gttattgaca
    57241 tgaccattca tatccaagtc gtaaaaacga acatggtaat ccttgctgat cggctcttcc
    57301 aaggattcat acttcggtcc acggataagt tttttatcaa aatcagactg gtaaggagcc
    57361 acaatctcag gttcaacagc atggactttt cgactgtcgc ggtccatgag aacaaaggtc
    57421 gccatcatat ggatgagctc ctgccccgct tcattataaa tagtaaagcg acggtagcaa
    57481 aaaagtcgat tgtagctcaa ggcttccgtt tcgatggtaa tttcttccgc aaaacgaggc
    57541 aaacgaacca cctcaatatc atattctgcg ataatccaga ccagattata gtcttccaaa
    57601 atggccttat cactaactcc cagttcaatc gattgcatcc ctgaaacttg cagtgacagc
    57661 aaaatcacat ctggaagttt gatatgaccg ttcatatcag ccatatcaaa aggaattttc
    57721 attttcattt gataagttaa gcacatgatc ctactccaaa ataaatcgtt ctgctacagt
    57781 atctcccaaa aagagacctc tctttgtcat gcgaacgtgg tcaccctcaa tctgcatgag
    57841 gccttgttga accaaatctc tgacaatttc tccataaagt ccagcaaaag actgtccaaa
    57901 tttttcctca aatcgcgcca tggaaacccc ggatttcttg cggagtccca agaacatttc
    57961 ttcttccatt tgctcctttt gactcaggtg atcttctgta atacaagcat tgccttcctc
    58021 aaccgcactg agataatgac gaatgggacc atgattttta tagcgtactc cattgacata
    58081 accagatgcc cctgcaccaa taccatagta ttcagcattg tcccagtaca tgagattgtg
    58141 acgactttca aagccgggtt tggagaaatt agaaatctca taatgctcaa aacccgctcg
    58201 ctccagctct gcaatgatgt actcaaacat ctccgcttct agttcctcct taggcagagg
    58261 caatttccca cgtcgcatcc ggttcataaa gaccgtatgg ttttctaaaa tcaaactata
    58321 caaactcatg tggggaatat ccagtccaat ggctttagcc acattttcct ttacttgctc
    58381 catggtctga ccaggcagag cataaatcaa atcaatggag atgttgtcaa aaccagccag
    58441 tttcaggcga tcgatatttt cataaatatc cttctccaaa tgactgcgcc caatcttttt
    58501 caacatctta tcatcaaagg tctggacacc tagcgaaaca cgattgacag ccgaattttt
    58561 caaaacagct atcttatccg catccaaatc gcctggattg gcttcaatgg tcaactcttc
    58621 caagacagac aagtccaagt ttttagtcaa gccattcagt aacacctcca gttgcggagc
    58681 cgacagggct gtcggtgttc caccaccgat ataaagggtt gacaactttt caatatcata
    58741 agaacgaaac tcttccagca gatgctctaa atagctgtcg actggctgat ttttgatgaa
    58801 gacctttgaa aaatcacaat aataacaaat ctgggtacaa aatgggatgt gcacataggc
    58861 tgacgttggt tttttctgca tagtaattat tataccacaa agactagatt ccagataaaa
    58921 atcaccatcc ccagatacat agtccgtccg gagatggtga tggtttattc ttctgttata
    58981 tcaatcacaa tctcttctga gtcatcaaga gcttcggctt tttcttgcca ttgctccttg
    59041 agattattta attgattttt tgatgcttct gtcgcttgaa aagcatagga tttagcttga
    59101 gcaagtatac tgtccacagt gatttcacct gactcaacct gttcttttgt tttcagaaca
    59161 aaatctgtag cctgctcctt aacttctgtc agtttttcac agacttgctc cttggcatac
    59221 tccggatctt ctctcaaatc atctagaaaa tcttgagcct gactgcaaac ttgtttgccc
    59281 ttatcacttg ttaaaaacaa ggcaagagct gcacctgaaa cggttcctaa aaggattgag
    59341 gataatttac ccataaggat tctccttttt tattttttga aaaatttact tgcaagacga
    59401 agagctgaca gacttgcacc agtcttgagt gtttttgaac cagctgatga agctttcttg
    59461 ctcaagacac gcgcatggtc attgaggtct gaaacagata gagataaatc tgcaacagca
    59521 ctgaagagtg gatcaatcgt agccaccttg acattgatat catctgccaa gacattgacc
    59581 ttagccaaca actcattggt gtgatgcaag gtcacatcca catctgaagt caaggtttta
    59641 atcgtctttt ctgtttcatc gatgacacga ccaagctttt gtacagtaat gatcagatag
    59701 accaaaaaga caatcaaagc tagggcaaca agaatatatg caacttctaa catttagttt
    59761 tcctcctctg taatatagta aggggccttc tttcgatttt gataaataac gatcattata
    59821 ccgagaccga taaagacaac tgacagccat tgggacactc gaaggctgaa gaacatgaga
    59881 ctatctgttc gcataccttc gatgaccata cgaccgaaac cataccaaat caagtaaaag
    59941 gccgtgatat gacctcgtct gagactcttc catttccgtc taaaaatcag aatcaaggca
    60001 aagccaagca gattccatag agactcataa aggaaagtcg gttgacggta gctcccctca
    60061 atatacatct ggtcacggat aaagccaggt agataatcca gattatccac tgttgcacca
    60121 taagcttctt ggttaaagaa attaccccaa cgccccaaac tttgagcaat cataacgcta
    60181 ggcgccgcaa tatctagaaa atcccaagta ttgatgagtt tacggtcagc aaagatatag
    60241 agcacaagag ccccagttat caaaccaccg taaatggcca aaccaccatt ccaaatggca
    60301 aaaatctctc ctaaattctg actatagtaa tcaaatcgga aaataacata gtagagacga
    60361 gctcctaaaa tagccaaggg aaaggctact aagataaaat ctaaaatatc gtctggtatg
    60421 atcttctttc taggtgcttc tttcatggtc aaataaaccg caagaatcaa gcctgtcaca
    60481 atacataagg cataccaacg aatggctagg ggtcctagtt gaatagcaat tggatcaagc
    60541 attttgcacc tcatttcgag ctatgagact tgtcagtcgt tcgtcgaaca aacgggtagc
    60601 atcaaagccc atttccttgg cacgataatt catggcagct gcctcaatca caacagagat
    60661 attacgacct gttttaactg gaatacgaat acgaggaatg gctacgccag aaacttcaag
    60721 ttcctctgca ttgtttccaa gacgatcaaa ggtcttatgc gtatcgtaat tttccaaata
    60781 gacagcaagc tgaacctgtg aagaatcctt gacagcactc gcaccgtaga gactcataac
    60841 atcgataata ccaaccccac gaatttcaat caagtgtttc aaaatttcag ctggttcacc
    60901 ccagagagta atctcatcct tggcaaagat atcgacacgg tcatcggcta ccaaacggtg
    60961 accacgtttg acaagctcaa gacctgtctc gctcttacca attccactat ctccctgaat
    61021 caagacgccc atcccataaa tatccatcaa gacaccgtgc acactggtac gttctgccaa
    61081 acgagaatcc agatagctag ataactctcc agataaacga ctggtagctg cacggctggt
    61141 taaaatagca atcttacatt ctctagcagc ctttaacatc tcctctggaa ccaccaaacc
    61201 acgggcaaca atgactgctg gtgtctcagg tagaaacatt tttttcaaaa cttcataacg
    61261 gctgttggaa ggcatgctga tcagataaga ccactccttc atccccaaaa gttgaatccg
    61321 ctctggtgta tagtagtcaa aatagcctgt catttcaaga ccaggtcgcg taatatccgc
    61381 tgtattgatt tccttttcaa gcaattctgg ttcaccatag acaatatcta gtctaagctt
    61441 ttcaatcact tcttttacta aaaccgacat catttcctcc ttcaaatgaa ttcttctctc
    61501 tattatatca aattgtagga ggaagtttca gatttttgca ggctttggag tatttattta
    61561 aaagaaaaag gactagattt ctctagcctt tcatttcaat tagaattttt tacgtttacg
    61621 agctacttct gatttacgtt tacgttttac agaaggtttt tcatagaatt cacgtttgcg
    61681 tgtttcttga agagtaccag ctttagtaac cgcacgtttg aaacggcgaa gtgcgtcgtc
    61741 aagagattca ttcttacgta ctactgtttt agacattttt ttcactccct tcaagttcaa
    61801 tatctatttc attctacacg taaaaggaat aattgtcaag caaaaatgcg gtttaatttt
    61861 gattttttct tccatttata caagagttga aagcgttcaa tagaacattg cttttttatt
    61921 tttcgagtaa gctaagcgct tcagcatctg cgatgatggt tacatcaggg tgattttgga
    61981 ggctacttgc aggtaggttc tcagtcactg ggccagatac tgttccggca atggcttctg
    62041 ctttcgactc accataagca aaaagaataa tagacttggc atccaaaatg tttttaatcc
    62101 ccattgaaat agcttgggtt gggacgtctt caatcttggc aaagaagcga gcattggctt
    62161 cgatagtaga ctggtcaagt tctactagat gcgtttgact gtcaaatgga gtaccaggct
    62221 cattaaagcc gatatgccca ttgcgaccga ttcccaagat ttggaggtca actggatggt
    62281 cagccaaaat ttggttgtag cgttcaactt cagcttcagc attgtcctta acaccacgag
    62341 gcaagaaact ttctttaaat ggtttttggt tgaacaagtt ttcttgcatg aagtaacgat
    62401 aagactgtgg attgtcccca tcaaggccca catactcatc aaggttgaca ctggttagat
    62461 ttgaaaaatc aaggtcactc tcaacaattt ccttgtaaaa ttcaagtggg ctacttcctg
    62521 tcgcaagtcc tagagtttga gctccattag ccaatttttc cttcaaaatc tcaaaagcaa
    62581 cttttccacc ttgaacttgg ttttcaactt taataacttt catcttttca tcctccattt
    62641 ctgtctatat ttattatatg gtatagacca atttttgtca agtgaaaacg atttaatttc
    62701 taaaaaaaga gcgtccaaac ttgaaacgtg ttataatgga taggattaga acttagaaag
    62761 aatgaacaaa tatatgaata cagctgattt tgatttccac ttgccagagg aattgattgc
    62821 ccaaacgccc cttgaaaaac gtgatgcctc caaactcctc atcgtcaacc gtgagacagg
    62881 agaaatgcaa gataaacatt tccactctat tattgatatg ctggaacctg gtgatgccct
    62941 tgtcatgaac gacacccgag ttctccctgc ccgcctctat ggtcaaaaag tggagacagg
    63001 aggtcatgtg gaacttctcc tccttaagaa cactagtgga gacgagtggg aagttctggc
    63061 taaacctgcc aaacgcctca aggtcggtac tcgtatcagc tttggtgatg gccgcctcag
    63121 cgctgtcgtt acagaagaat tgacccacgg gggacgcatt gtccgctttg aataccaagg
    63181 aattttccta gaagtcttgg aaagtctggg agaaatgcct ctgccacctt atatccacga
    63241 aaaattagat gaccgtgaac gttatcaaac cgtctacgcc aaggaaagcg gctctgctgc
    63301 agcaccgact gctggtcttc acttcaccaa agaactgctg gcagaaatcc aagctaaggg
    63361 tgttcatcta gtctatctga ctctccatgt cggactcgga acctttagac ctgtttctgt
    63421 ggataatctg gacgaacacg aaatgcactc agagttctat caactttctg aggaagctgc
    63481 tgccaccctt cgctctgtca aagaaaatgg tggtcgcgtc atcgctgtcg gaaccacttc
    63541 tatccgcacc ttggaaacta ttggttccaa gtttgatggg caaatccaag cagattctgg
    63601 ttggaccaat atctttatca aacctgggta tgagtggaag atcgtggatg ccttctcaac
    63661 caacttccat ctgccaaaat caactctggt catgttggtt tctgcctttg caggccgtga
    63721 attagtctta gatgcctacc accatgccat ccaagaacac taccgcttct tcagttttgg
    63781 tgacgccatg tttatttatt gagaaagaat ttctctaatt cttctaatac caataaatcg
    63841 ctaagatatt atttcaaaga acatctacaa ttgaaactct agctagctgt agaagacgcc
    63901 tagtacattg aaattaaaat gcttccccct agcttcgaaa atattgccat agattgcgtt
    63961 gactctccaa attgattcat ctatatttta tttcagcttc ctatattttc ttcgctgttt
    64021 gtaaatcaaa atgcaagaca catgagtagc accatatttg ttactcttat ctgtcctctc
    64081 aagagactat tatgagttat ttcagaatca ttcactactt tgaccctgac tctccttagt
    64141 ctcaaaatca aagacttata ctcttcaaaa atctcttcaa accgcgtcaa cgtcaccttg
    64201 gattatatat gtgactgact tcgtcagttc tatctacaac ctcaaagcag tactttgagc
    64261 aacctgcgac tagttttcta gtttgctctt tgattttcat tgagtattaa acaaaaagtg
    64321 aacaaatctg aattctaatg tacagaagac taggcttgtt cactttttta tagtcgctat
    64381 aagatgacct tatctatagc tttttatata taattatata ttcagacata ctattatcaa
    64441 ttttgtcgca gggaggaatc tgttaacgca cccattcacc attatcattg actctatagc
    64501 catctatact tgtattgacc gctaactcac ccgatgcatt tacataatac catttaccac
    64561 caacttggaa ccattgattg actttcatag aaccgttgct gttgaggtag taccatgaac
    64621 cattaacttg tacccaacct gttgccatgg aaccatcagt attataaaaa taccacatac
    64681 cattttcttg tttccagtct gttgttggag caactgcttt agctggttct actgctacat
    64741 ctgttccttg gttagatgta acagatacag gatacgaagg aatagatgat tgctcaggaa
    64801 caacaacttt ttcaggttct ctcgtccctc tccttatacg tctttttacc atctctttag
    64861 taatttgacg agaagtagtt tcttcaatta ttccatcacg ttcatctaca gtatagattg
    64921 tagtaagagt aatttaccaa tttctcctac ttcttctact tcttgacttt tatcaagagt
    64981 tgggccatcg agatattctg tttcgattgg aatttcttgg acaagaactt ggggcttggt
    65041 tcctttttta acaactcttg tttgagagtc tttttttgac ttaaagtact ctcagttact
    65101 tgtccactct ttccatctac attataagtt atcgttgtaa ctgttttccc attctttcct
    65161 agagtaatct cttgctcctg tcctgcagaa aggtcattgt ctgcttcata tttagtagca
    65221 aatggaacaa gaacttcttc aatcttgctt ttagctggaa ctttgataac tgtatccgtg
    65281 gcttcttttc tatcaacagt aacctgttcg gtaacataac cagtctctgg attaacatcg
    65341 taggtccttg tcgtagttac atagccatcc tctccgtcaa ttgtaacagg attttcacta
    65401 cggtcttttg tttcatcttt ttcaaaacga attcgcgtac ttgaaatttt cttggttact
    65461 accttaggtt tagtcgctac ttttacaata atatccccat tgtcagcgtc atcatactct
    65521 attccctctt ctttatctct agtatcatct ctgacatatt gaatcccatc agcagcatga
    65581 gcaaaacttg tattcagatt cctcctaaaa ataaagttag cccgattatc gcagaaccaa
    65641 aaatctttcc gagtttacgt attgcataac gcttattagt attagatttt gccattacat
    65701 cctacttcta gtatagcatc ttttctatca aacgttaaac aatatacttt atatataaaa
    65761 tagacttaga atgatatatt gattattgaa ctaacacttt aactatatcg taatcaatct
    65821 catatataaa ggattgcaga catctgatct aaatacatgc taatatattt agatacaaac
    65881 attccaactt gataattttc actcatcttt caacattcct tacacaacga tgcagtataa
    65941 atagaatagt tttctcatca gaatgagact attttaatat tagataattt gatagaaaaa
    66001 cataaataaa attggttgaa tttaattccc taactcgata gaggattcta ttttaaattt
    66061 aacaacagct aggattacac tataaaaagt acattaccac ctgttcggct ggagaatcta
    66121 gtcgattagc tccctcttag ttacaagctt aaagcgattt tttaactaat actaaaccag
    66181 attaaagaag gaactagaac atctgtcttg tactaatcaa tatgctattt taaaattgca
    66241 aataaacttg gaatgctaat tattatattt acaataaata gttgacttcg atagaaacag
    66301 aaaatagaat tcaacattct tccctactta taccataata aataagatcc gcaagatagc
    66361 cttttctctc tacaccatta acaatggttt gtagatagga cattccagcc ttttccatga
    66421 cacgacctga agctgggttg agactggcat aacgtgctct gaccttttga aaacctgctt
    66481 gagtaaaaca aaagtccaag acagctttca aggcctctgt catcatacca tgtccccagt
    66541 aagccttgcc tagcacatag ccgatttcac agcttaaatc agcctcgtct atcttaacga
    66601 tgctgatatc tcctatcact tgctctgggt tttcttttag acaaatggcc catttgtaat
    66661 agttgagatt agtataggaa gcaacccaat tgcgaatcga gtttcgagtg atttcgacat
    66721 caggatgggg atcccaggta acataggtca gattctcagt ggatgaagcc caattttgaa
    66781 acatggcttc tgcatcactc tccacaaatc ttcttaaaat caaacgttct gtctgtaata
    66841 tttgcgtacc gatagatttc atgatgctac ctcacttcct tatttctata ctcgtagtaa
    66901 gaaggctcaa ctcagtaaca gctagaaaac gagtttgtct tctaatttct tgacgcagtt
    66961 gctgcctggt ttgaaatgcg ctctagcaag ctttttcaaa cctagtcatc gttgcagggg
    67021 taagacgatg aaatcgaact cttcgagtta ctgaatctgc ctcattttct tatttctaaa
    67081 ctcggggttc aagatccccc agaccttctc tcactttctt atttcaagat gagaggctga
    67141 aaacctccac tggaggtttt tcttgctttt taatttcagg gcaagaagct aaaaaggtcc
    67201 cccggacctt cttcgctttc tcatttctag gctcagggta aaaacctcca gtggaggttt
    67261 ttactcccaa aagtcatcaa atacagtgat gggtaagtgg cgtttgtgtt ggcctttgtg
    67321 ccaccagttt tcaatggtcg cttgagcttc tgggctgatt gttttgcctt ctaggtagtc
    67381 gtcaatctct gcgtaggtga ctccaagtgc gacttcgtca gctaggcctg gtttatcttc
    67441 ttctaggtct gccgttggga ttttttcata aagggctggc tctgcgccaa gtttctgcaa
    67501 gagctgtttt ccttggcgtt tattgaggcg gtaaagaggg agaatatccg caccgccgtc
    67561 accaaacttg gtaaagaaac ctgtgatatt ttccgcggcg tggtctgttc caatgaccgc
    67621 tccgctatgg gaaccagcaa gggcatactg agcaatcata cggcaacgtg ccttgatatt
    67681 ccccttgttg aagtctgaaa caggactacc tgtcgcttca actgcagctg tcatggcatc
    67741 agctgattcc ttgatattca caaccaagct gacatctggc tggatgaagg ctagggcttt
    67801 ttgagcatct gcttcatcag cttgcactcc gtatggcagg cggacagcga taaatttgta
    67861 gctatcgtct cccgtttcag ctcgcagttc ttccatagct aattgcgcca aacgtcctgc
    67921 caaggttgag tcttgtcccc cagaaatccc tagtacaaag gtttttagga agggatgttt
    67981 tttcagatat ctttttaaga aatcaataga acgacggatt tcttcctggg catcaatcac
    68041 tggtttgaca cccagctctt ggataatcgt ttcttgcaaa ctcattcttc ttctccttca
    68101 ccaagggctt ccttgcgcat cttatcaatc aagtccatct tatcttgcca tacatcacgc
    68161 gccaaatcca ctggatagtg ctgcggattg agcacacgct tatactcatc ccacaacttg
    68221 tcaaattcct tacgggcata atcctgaatg tcagtcaaac taggcaagtt gtaaactaat
    68281 attccttctt tgaagatatc caccaagaga ggaacggcat caaaattacg aaccgtcttc
    68341 ttgatgtatg tataggtcgg atggaacatc ttgatttctg tcatgtcgct aatatccaca
    68401 ccatcataag tgatgtagtc accttctgac ttgccttttt cacgactggt aatgcgccac
    68461 acctgcttct tacctggcgt cgacactttt tccgcattat tagacagctt aatcgtattg
    68521 cgcatctggc cgttttcatc ttcgattgca acaatcttgt aaaccgcccc aagagccggc
    68581 tggtcatagg ctgtaatcag cttggtaccc acaccccaga catcaatctt ggccttttgc
    68641 atcttgaggt taaggatggt attttcatct agatcattag aagcataaat cttagcctct
    68701 ggaaatccag cctcgtccag ttgctgacgg actttcttag aaatgtaggc aatatcccca
    68761 gagtcaatcc gcacacccat aaagttaatc tgatcaccca gctcacgcgc cacctgaatg
    68821 gcagctggta caccgatgcg aagggtatca taggtatcca caagaaagac acaatttttg
    68881 tgggtcgcag cgtaagcctt gaaagcctca tagtcattgc cataaacctg taccaaggca
    68941 tgggcatggg ttcccaaaac aggaatgtca aagagcttac ccgcacgcac gttgctggtt
    69001 ccattggcgc caccaatcac cgctgcgcgt gttccccaga tggccgcatc catttcttga
    69061 gcccgacgtg tcccaaactc catcaagggt tcatcttcga taaccgaacg aatacgagct
    69121 gccttcgtcg ccaccaaggt ctggtagttg acgatgttca aaagagccgt ttcgaccaac
    69181 tgacattggg ctagaggtcc ttccacctgc acaatcggtt cattagcaaa aaccaaatcc
    69241 ccttcttggg cagaacgaac ggtcaactcc aacttgaaat tgcgaaggta atccaagaac
    69301 gccccatgat aaccaagcga ctccaaatag gctatatcac tatctgaaaa acgcaagtct
    69361 tcaagatagt tcacaattct ttccaaacct gcaaaaaccg catagccgtt cttaaaaggc
    69421 tgttggcgga aatacacctc aaagaccgcc ttcttattgt aaatcccttg atcaaagtaa
    69481 acctgcatca tgttgatctg gtacaagtcc gtgtgcaatg tcaaactatc atctggatac
    69541 atacttttcc tacttcctta gctagaaacc catgaaaatt ttcaagaact ttcatgtatt
    69601 ccaataaatt agtactatta tatcacattt tagctggatt gagaaaagag taacaagcta
    69661 ttctccactc tccaattcat ccatatcttg ttcaaatttt ttctgagccc attcgccata
    69721 gctcttaaga ccaagattgc caataaagac ccacggaagg taaatgacat aagtaatgac
    69781 ccaagcagac aggtatttaa aattcaaagg attgtgctga taaatttcta tgttgaattg
    69841 ataattctgc aacatcaaaa gagccgtaat agccaaggtt aggaaaaaac aacccaaaat
    69901 cgtaaaatga aaacgactat agtaggtcac tcccagataa cgggcacgat tgaaaaagta
    69961 aaatgtccct atgatgataa cgattagcag catattagaa ttaaaaaggc ttggtgctaa
    70021 tactgaaatg atataagata ggagcgacaa agcaatgcag atatagaaac tttcagagcc
    70081 cgctttattg aacagttgtt cttctctttc gtctagtaat tgataataat aaaatctatt
    70141 tttcatcttc ttcctcccaa aatagttggt ctagggtttt ccctaaacat ctgcaaatag
    70201 actggcagag cgagagactg ggattgtatt ttcccgcctc tatcaaacca atagtctggc
    70261 gtgtcacccc gacagcctct gccagttgac cttgtgttaa atcacgctct acccgagcta
    70321 attttaattt taaattttta gccaccttcg tcctccttat agttttaata ctcatctact
    70381 cttaaaaaat ccaaaaccaa cacaagctat cagctattta ttataacccc attaatttgc
    70441 actccagtat tatcttcagc cgaaaatcag tattttaggt tgtttgaaat aaacttccta
    70501 gtttactctt ttatttttat ttagtattag ctttagtagg atcttttaaa cgagttttta
    70561 ttgcttatat ttcttgttta gtttagttgg tttcatatca ctattatata atgcttttgg
    70621 aaatgagcct agtataagtc aaaaacgtgt tgaatagtga aagcaggagc ataccaagat
    70681 gactgatttt ttactgtatt ttaggtatgc aaaataatac taaatgaaac taaaatgaat
    70741 acttcttgct tttcttgaga gtgaaaaagt acaataaaat gattgtagtg attagcacaa
    70801 gatactgact aatagacatc gtatttgaag ccacaaatac aggtaaagaa taaaaaggaa
    70861 gaagttcaat tgctttgata aacaaatcat tactagtatt catcatcatc gtatttaata
    70921 tattagggat aaagagtagt aaagctacta aaataccaaa taccaagcca cttttcaatt
    70981 tgtataaata gaaaatgtag gataatagaa aataaaacag gactaacaaa attgtattga
    71041 ctacaatagc tactataaaa tctaatccta aatcacctgg aatacccaat ttacttacta
    71101 tgactagtaa cacaatgcca ttccaagcat aaataatgga aactgagatg gcatatagaa
    71161 aattagacaa gacgtaaatc atccgattct tctgttgatt ataaaacaaa cttaccgtat
    71221 tgtgggaaaa atctctacta atgactcgat tagcatgtat aacagccatt aacataccga
    71281 gcatggcata aaagtttgaa atatgcttaa taccaagcga tgtcccttga gtctttagaa
    71341 taaagaatgt aagcaatatc ggcggtataa acgagataag caaactgaga tatattacgc
    71401 ctgatgaata taaatttctt atactttcct taagaaaatt caatttattt aatttcatga
    71461 ttataacctt cctttatttt gaacgattta ggtaaatatc tttaagcgtc tcttttttag
    71521 tttcaaaatc aactacttta atagagtttt cgttaaaaaa tttaaaaagc tcactacttt
    71581 gaatattccc agacatagta attctcagtc cctcttcctg aacaatatct ccaaattctt
    71641 gtttggtaat gaaaatgtct ctatctgtag ctgatgaaaa agctatctca aacaagaaat
    71701 tatgactatc ttttcctact ttttgaaatg tcaaaagccc gctctccaag aaaagaaccc
    71761 tctcacaaat ttcttcaata tcttctaatt tatgactcga tattaaaatt cccacatttt
    71821 catgtaaagc taaatttttt agaaccgcta aaactatttg tgatgattca atatctaaac
    71881 cattagtcgg ttcatctaaa atcaatatat caggttccgt aacgagagtt agaagcaaag
    71941 ctaatttttg ttttgtaccc aaagaatagg tctttacttt tttattaata gactgagtca
    72001 aatctaactc ttggatcaaa cttctaaatc tttcttgatt gtagtcaaca ccatataaat
    72061 ttgacaaata ttttaaattc tctaaacctg ttttagataa aaataatttt ggttcttcga
    72121 ttaaataccc aatattatca ctgcttataa tattacctga agtcggttga ttattctgag
    72181 caagaatttt catcaacata ctcttaccaa ctccatttct ccctactaga ccaacaattt
    72241 cacccttgtt aagtgcaaaa tttatgtctt tgagaatgat tgaatgacca taatgcttac
    72301 ttacatttat aacttacatt ttttattcct ccattaatat tcatggtttg ctctttgatt
    72361 cttattgagt ttaaaaagtt gcgcctcttt ttaacaacat tatatcatat atctaactta
    72421 atgcaatata taaatatcat tttgtaaaat tttattaaca aaaaactctc tacaacaaaa
    72481 taatagagag ttttctgctt attaattttt ttcaaaatat ctaagacatc acttctttgt
    72541 ttaatttgat aggctttgat acctaagctc cgactttatc acttaaaaaa taaaaaagga
    72601 cagctaatct cttgcgcatc aagggatttc gccattcttt aatctcgttt aagtgttgta
    72661 tatggagctt tgcataattt tttaaaacta aacaactaca ttaagcacga actgtgacgc
    72721 tggttccatc ttccttataa a
//
LOCUS       DAVLHM010000003        69051 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLHM010000003 DAVLHM010000000
VERSION     DAVLHM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69051
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.003"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..275
                     /locus_tag="VXE45_000215"
     CDS             <1..275
                     /locus_tag="VXE45_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0788325.1"
                     /translation="WYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYL
                     NESGSMATGWFTVSGQWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(754..903)
                     /gene="rpmG"
                     /locus_tag="VXE45_000216"
     CDS             complement(754..903)
                     /gene="rpmG"
                     /locus_tag="VXE45_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0788326.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(919..1101)
                     /gene="rpmF"
                     /locus_tag="VXE45_000217"
     CDS             complement(919..1101)
                     /gene="rpmF"
                     /locus_tag="VXE45_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0788327.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1253..1453)
                     /locus_tag="VXE45_000218"
     CDS             complement(1253..1453)
                     /locus_tag="VXE45_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0788328.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1456..2463)
                     /locus_tag="VXE45_000219"
     CDS             complement(1456..2463)
                     /locus_tag="VXE45_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0788329.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2654..4684
                     /locus_tag="VXE45_000220"
     CDS             2654..4684
                     /locus_tag="VXE45_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0788330.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4688..4972
                     /locus_tag="VXE45_000221"
     CDS             4688..4972
                     /locus_tag="VXE45_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0788331.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4985..6331
                     /locus_tag="VXE45_000222"
     CDS             4985..6331
                     /locus_tag="VXE45_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0788332.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            6335..7192
                     /locus_tag="VXE45_000223"
     CDS             6335..7192
                     /locus_tag="VXE45_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0788333.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            7189..8121
                     /locus_tag="VXE45_000224"
     CDS             7189..8121
                     /locus_tag="VXE45_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0788334.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8354..10057
                     /gene="ilvD"
                     /locus_tag="VXE45_000225"
     CDS             8354..10057
                     /gene="ilvD"
                     /locus_tag="VXE45_000225"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0788335.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10218..10298)
                     /locus_tag="VXE45_000226"
                     /pseudo
     CDS             complement(10218..10298)
                     /locus_tag="VXE45_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10356..10697)
                     /locus_tag="VXE45_000227"
     CDS             complement(10356..10697)
                     /locus_tag="VXE45_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0788336.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10821..11672
                     /gene="rgg"
                     /locus_tag="VXE45_000228"
     CDS             10821..11672
                     /gene="rgg"
                     /locus_tag="VXE45_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0788337.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11865..13112
                     /locus_tag="VXE45_000229"
     CDS             11865..13112
                     /locus_tag="VXE45_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0788338.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            13190..14479
                     /locus_tag="VXE45_000230"
     CDS             13190..14479
                     /locus_tag="VXE45_000230"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0788339.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            14470..14550
                     /locus_tag="VXE45_000231"
                     /pseudo
     CDS             14470..14550
                     /locus_tag="VXE45_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14820..15134
                     /locus_tag="VXE45_000232"
     CDS             14820..15134
                     /locus_tag="VXE45_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788340.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            15144..15350
                     /locus_tag="VXE45_000233"
     CDS             15144..15350
                     /locus_tag="VXE45_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0788341.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15350..15547
                     /locus_tag="VXE45_000234"
     CDS             15350..15547
                     /locus_tag="VXE45_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788342.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQGDQFVWLYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            15550..16284
                     /locus_tag="VXE45_000235"
     CDS             15550..16284
                     /locus_tag="VXE45_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0788343.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            16296..16937
                     /locus_tag="VXE45_000236"
     CDS             16296..16937
                     /locus_tag="VXE45_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0788344.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16955..17185
                     /locus_tag="VXE45_000237"
     CDS             16955..17185
                     /locus_tag="VXE45_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788345.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17537..19300
                     /gene="aspS"
                     /locus_tag="VXE45_000238"
     CDS             17537..19300
                     /gene="aspS"
                     /locus_tag="VXE45_000238"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0788346.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            19278..20219
                     /locus_tag="VXE45_000239"
     CDS             19278..20219
                     /locus_tag="VXE45_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0788347.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20429..20509)
                     /locus_tag="VXE45_000240"
                     /pseudo
     CDS             complement(20429..20509)
                     /locus_tag="VXE45_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20645..21631)
                     /locus_tag="VXE45_000241"
     CDS             complement(20645..21631)
                     /locus_tag="VXE45_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0788348.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21641..22441)
                     /locus_tag="VXE45_000242"
     CDS             complement(21641..22441)
                     /locus_tag="VXE45_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0788349.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22702..23544)
                     /locus_tag="VXE45_000243"
     CDS             complement(22702..23544)
                     /locus_tag="VXE45_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0788350.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23546..24838)
                     /locus_tag="VXE45_000244"
     CDS             complement(23546..24838)
                     /locus_tag="VXE45_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0788351.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24949..26220)
                     /locus_tag="VXE45_000245"
     CDS             complement(24949..26220)
                     /locus_tag="VXE45_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0788352.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26770..28287
                     /gene="malQ"
                     /locus_tag="VXE45_000246"
     CDS             26770..28287
                     /gene="malQ"
                     /locus_tag="VXE45_000246"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0788353.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28313..30571
                     /gene="glgP"
                     /locus_tag="VXE45_000247"
     CDS             28313..30571
                     /gene="glgP"
                     /locus_tag="VXE45_000247"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0788354.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31616..32188)
                     /locus_tag="VXE45_000248"
     CDS             complement(31616..32188)
                     /locus_tag="VXE45_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788355.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(32811..33659)
                     /locus_tag="VXE45_000249"
     CDS             complement(32811..33659)
                     /locus_tag="VXE45_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0788356.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33811..34089
                     /locus_tag="VXE45_000250"
     CDS             33811..34089
                     /locus_tag="VXE45_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788357.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            34091..36154
                     /locus_tag="VXE45_000251"
     CDS             34091..36154
                     /locus_tag="VXE45_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0788358.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36232..37488)
                     /locus_tag="VXE45_000252"
     CDS             complement(36232..37488)
                     /locus_tag="VXE45_000252"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0788359.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37630..40095
                     /locus_tag="VXE45_000253"
     CDS             37630..40095
                     /locus_tag="VXE45_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0788360.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            40160..41071
                     /locus_tag="VXE45_000254"
     CDS             40160..41071
                     /locus_tag="VXE45_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0788361.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41301..41999
                     /gene="dapD"
                     /locus_tag="VXE45_000255"
     CDS             41301..41999
                     /gene="dapD"
                     /locus_tag="VXE45_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0788362.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            42067..43197
                     /locus_tag="VXE45_000256"
     CDS             42067..43197
                     /locus_tag="VXE45_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0788363.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43209..43748
                     /locus_tag="VXE45_000257"
     CDS             43209..43748
                     /locus_tag="VXE45_000257"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0788364.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43732..44409
                     /locus_tag="VXE45_000258"
     CDS             43732..44409
                     /locus_tag="VXE45_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0788365.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44481..45380)
                     /gene="galU"
                     /locus_tag="VXE45_000259"
     CDS             complement(44481..45380)
                     /gene="galU"
                     /locus_tag="VXE45_000259"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0788366.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45402..46418)
                     /locus_tag="VXE45_000260"
     CDS             complement(45402..46418)
                     /locus_tag="VXE45_000260"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0788367.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46640..47043
                     /locus_tag="VXE45_000261"
                     /pseudo
     CDS             46640..47043
                     /locus_tag="VXE45_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823968.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(47158..47583)
                     /locus_tag="VXE45_000262"
     CDS             complement(47158..47583)
                     /locus_tag="VXE45_000262"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788368.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(47651..48301)
                     /gene="phoU"
                     /locus_tag="VXE45_000263"
     CDS             complement(47651..48301)
                     /gene="phoU"
                     /locus_tag="VXE45_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0788369.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48316..49068)
                     /gene="pstB"
                     /locus_tag="VXE45_000264"
     CDS             complement(48316..49068)
                     /gene="pstB"
                     /locus_tag="VXE45_000264"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0788370.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(49070..49885)
                     /gene="pstA"
                     /locus_tag="VXE45_000265"
     CDS             complement(49070..49885)
                     /gene="pstA"
                     /locus_tag="VXE45_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0788371.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(49878..50741)
                     /gene="pstC"
                     /locus_tag="VXE45_000266"
     CDS             complement(49878..50741)
                     /gene="pstC"
                     /locus_tag="VXE45_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0788372.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(50859..51734)
                     /locus_tag="VXE45_000267"
     CDS             complement(50859..51734)
                     /locus_tag="VXE45_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEV0788373.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(51901..53232)
                     /locus_tag="VXE45_000268"
     CDS             complement(51901..53232)
                     /locus_tag="VXE45_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0788374.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMVLTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(53233..53940)
                     /locus_tag="VXE45_000269"
     CDS             complement(53233..53940)
                     /locus_tag="VXE45_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0788375.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(54024..54326)
                     /locus_tag="VXE45_000270"
     CDS             complement(54024..54326)
                     /locus_tag="VXE45_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0788376.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(54313..54534)
                     /locus_tag="VXE45_000271"
     CDS             complement(54313..54534)
                     /locus_tag="VXE45_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0788377.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            54496..55054
                     /locus_tag="VXE45_000272"
                     /pseudo
     CDS             54496..55054
                     /locus_tag="VXE45_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55369..57060)
                     /locus_tag="VXE45_000273"
     CDS             complement(55369..57060)
                     /locus_tag="VXE45_000273"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0788378.1"
                     /translation="MNTKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            57196..57642
                     /gene="argR"
                     /locus_tag="VXE45_000274"
     CDS             57196..57642
                     /gene="argR"
                     /locus_tag="VXE45_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0788379.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLESVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            57693..60227
                     /gene="mutS"
                     /locus_tag="VXE45_000275"
     CDS             57693..60227
                     /gene="mutS"
                     /locus_tag="VXE45_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0788380.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            60374..62068
                     /gene="patA"
                     /locus_tag="VXE45_000276"
     CDS             60374..62068
                     /gene="patA"
                     /locus_tag="VXE45_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0788381.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(62399..62668)
                     /locus_tag="VXE45_000277"
                     /pseudo
     CDS             complement(62399..62668)
                     /locus_tag="VXE45_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            62860..64626
                     /gene="patB"
                     /locus_tag="VXE45_000278"
     CDS             62860..64626
                     /gene="patB"
                     /locus_tag="VXE45_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0788382.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAHQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPIMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            64765..65454
                     /locus_tag="VXE45_000279"
     CDS             64765..65454
                     /locus_tag="VXE45_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0788383.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            65458..65637
                     /locus_tag="VXE45_000280"
     CDS             65458..65637
                     /locus_tag="VXE45_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788384.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            65624..66973
                     /locus_tag="VXE45_000281"
     CDS             65624..66973
                     /locus_tag="VXE45_000281"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0788385.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            67097..68557
                     /locus_tag="VXE45_000282"
     CDS             67097..68557
                     /locus_tag="VXE45_000282"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0788386.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            68571..69005
                     /locus_tag="VXE45_000283"
     CDS             68571..69005
                     /locus_tag="VXE45_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0788387.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        20253 a        12838 c        14935 g        21025 t
ORIGIN      
        1 tatggtatta cttaaacgaa tcaggttcaa tggctactgg ttgggttaaa gacaaaggct
       61 tatggtatta cttaaacgaa tcaggttcaa tggctactgg ttgggttaaa gacaaaggct
      121 tatggtatta cttaaatgaa tcaggttcaa tggctactgg ttggtttaca gtttctggtc
      181 aatggtacta tacctataat tcaggagatt tattagtaaa cacgactaca cccgatggct
      241 atcgagtcaa tgctaacggt gagtgggtag gataggtatc cattagctaa atctaatcat
      301 tctgaactaa aaaatcttct tacatatgta ggaagatttt ttggattctc aaaactagtt
      361 taaaagacta cgctatttaa accaatttta agaatggata tataaggata ttcagaaatc
      421 tagttggtca acttttgtat tttgaatata ccttagatgg tgacgatgtc ttggtatatc
      481 tggtactcac ttacatattc taacttattt taactaagat acaactgtag ttggtgaatt
      541 tgctacaaat agtgtagagg cgttatttga aaaatataca aaaaaggaac cccaacttac
      601 atttgagttc ctcttgcttt taattgtccg aatccgtatt cttatttcaa taatgtagtc
      661 attcgaatga tttcccttgc aatatagtga aattaacaaa aagaaaaaac gctgatcaag
      721 cgtttttctt ctgtattgat tcgtattgaa tgcttacttc acttctgtaa acacaacgtg
      781 tttgcgaagt tttggtgagt atttcttcaa ttgaaggcgg tctggagtgt tacgtttgtt
      841 tttagaagta aggtacaagc gttcaccaga ttctttgtgt tcaagtgtaa tatttacgcg
      901 catagtatct cccttctatt attcagctga tgcagcttta gcgattttac gtcctttgta
      961 gtatccttta agtgatacac ggtgagaacg tgagtaatct ccagtagttt cgtcaaagtt
     1021 tacagatgga gctgttactt tgtagtgtgt acgacgtttg tttttcttcg cttttgaagt
     1081 gcgacgtgca ggtactgcca ttttgatttc tcctttaggt atttatattc gattcaatct
     1141 actgattttc atcaaccata ctaggataac acattttttt tgtaaagtaa agttacttga
     1201 caaaaaaaga tgaaaaaatt ctcctatccg acacggcaga caggagaagg tgttaaatat
     1261 caatctcaaa tggttcgtca atggtttctg atacgtattt tccgtctttt ttccgttgct
     1321 tgacacactc tgtgaggaga tattctattt gcccattgac tgaacgaaag tcgtcttctg
     1381 cccatgatgc gagtgcagcg tataactttg ttgagagtcg aagggggatc tgcttttttt
     1441 tagcttcagc catctttagt aaagacttcc tgtgttgaca attggttgtg catcatgatt
     1501 gccacaaaga acgacaagga gatttgaaac catggcagct tttcgttctt cgtcaagttc
     1561 taccaattcc ccttcattga gccgttctag tgccatttca accattccta cagcaccatc
     1621 tacaatcatc ttacgtgcat caataatggc agatgcttgt tggcgttgaa gcataacggc
     1681 agcaatttct ggagcataag ctaggtaagt gatacgtgct tcaaggattt ccaagccagc
     1741 atcctcaaca cgactttgga tttcttcacg aatacggtta gcaacaattt cgctagagcc
     1801 acggagacta ccttcatctg cttgcccgtc acccgtagta tccacattag gagacacatc
     1861 gtaaggatag atgcggacaa tattacggag ggcgctatca cattgcaatg aaagatattc
     1921 tttgtagtta tcaacgttga agactgcctt agcggtatcg acaactctcc aagttaccgc
     1981 gataccgatt tctacagggt ttcctaagca atcattgatt ttttgacgag aattgctcaa
     2041 ggtcatgact ttgagggaaa tctgtttctt gccaatttca agatttacat cattgtcatt
     2101 tgatgattta gctcctaaaa aaggagattt tgtgctaaca tcaccacttt gtccaagtcg
     2161 agtgtggttt gcagggttga ctgctacgct gaagggattg acaaagtaaa aaccaggttc
     2221 tttgatggta cctgtataat taccaaagag tgtcagaacc agagcttcct gaggtttgac
     2281 aacttttaaa ccagcatgag ctagacctgc aattacgatt agtaaaggtc cgataataat
     2341 tccaaaaatg ttttccgaac caacacccat tataaatata aagataccaa gtacgattgt
     2401 caattcaatg agaatcaatg cgaatacacc atttggtttt gaattgatga gtttttcagt
     2461 cataagaatg acctcctatt atttgatatc taaatgatat cactttgttt ttaaaagtca
     2521 atagaaagtt gaaaataatc actaaaaagt ttcagcccaa taatttcttt taaaaggtga
     2581 gattatattg tgctcaaata ctcttttatt cttataattt ttacactata attgtagtta
     2641 gaaaggaaga gaaatgtttg attatagagc actagttatt ttgatgactt tgatggatca
     2701 ttgtgagcta tcattatatg aattatctgt taaggtgagc ttacctataa aggaagtcaa
     2761 agaaggaata gattatttag tgccttatct agctaataaa gggatagtgc tggataaaaa
     2821 acaaggtcgc tatagtttat caaatcgtac gaagcagtct ttgacagata ttattaagtc
     2881 ggatgaattg gttttaccaa agtcgactcg cttagcttta atctatcttt acactttttg
     2941 ccgattagat tttatatcga ataatcatta ccaagacttt ttgaaagtaa gtaagaatac
     3001 aaccttatct gatattcaat cattaagaaa gattatgtta gataatgatt tggagctagg
     3061 gtacagtaga gcaaaaggtt atactttaca cggttcagag tggaataagc accgcttagc
     3121 ttttcaaatg gttagtgagt tgctggaatc ctccataggg atttggggtt tggattatgt
     3181 tttatccagt tgggggtatt cattaactta tgatttgata aatcaggtag ttaaagatta
     3241 ttatgagaag ctacagctag tacctattgt taatcaatta aaagtttgcc ttttcggttt
     3301 agtattcatt ctgtgtaggt atcaaaggga tgttgaaaga gtatgtcttt cagagacatt
     3361 agtatctcct gttattcaag atataacgac tattttattg gatacagtgg ttgatttggg
     3421 aattatagat acggtgtttt ctgaggatga ttatcgctat atcaccgttt tattatcaag
     3481 ttgctttgaa ggtgaagtag atgttgctcc ggtttacttt aatcaattaa cagaggctat
     3541 tataagtaga atggaagata tttctttgtt acattttaaa caaagggaag gattgagaga
     3601 aaatcttcgc cgccacctta taccggctta ctatagatta aagttcggcc tacctagttc
     3661 aaatgaatat gtattgcatg ttaaagaaca ttatcctgat ttatttgaat tagtcaaaga
     3721 ttctttgatg cccttgatgg acgctattga caatcccata cctgatagtg aaacagcata
     3781 ttttgttatc catttcggag gttatttaaa gaaagcagat actttgcctc aaaaatgcta
     3841 taaagcagca atcatttgtc ctaatggtgt tagttcttca ttgatgttaa aagagaatct
     3901 attagcatta tttcctcaaa ttgagtttat aggaacctca aagattgatg atttacaggt
     3961 gaaagctagt agtgactatg atatggtttt ttctaccata aaggtggaga cagaaaagcc
     4021 aaattatcta gtttcggtta tgatgactga agagcaagca atacaactag tagaactagt
     4081 gttaaaagat tttccgaatt tagagtatgg ggattttgag attgaacaaa tcctgaatat
     4141 tgtcaaaaga tatggaatta ttacacaaga attggaatta agattggcgt taaagaatta
     4201 tctttaccaa aaaaatgata gaaaggaaat tgtaccagtg ctagaacaac tcattaccaa
     4261 agaaacctat caggttagtt cgcaaaaatt aggatggaag gaggcgattc gtttagcagc
     4321 taaaccgctt ttggatcaag ataagataac tgagaactac cctgaggcaa tgattcaaaa
     4381 agtagaagag tttgggcctt ttattaattt agggaaggga gtagcaattc ctcacgctcg
     4441 gccagatgaa ggtgtgaatg aaataggaat gtcaatgtta gttttggaag aaccgattta
     4501 tttattggat aatccagaac aagaggtaag attgttgatt tgtattgcag ccattgataa
     4561 tgagagtcat ttaaaggctt tgtcacattt aacaacaatt ttaagagata aaaatcatgt
     4621 tcaaacttta atatcatcaa aaaactatga tgacattaaa atgataatta aacaggagga
     4681 ttagataatg ttaaaaattg gtacagcttg tggttcagga ttaggttcaa gttttatggt
     4741 acagatgaat attgaatctg tattgagtga tttgaatgtt tcggatgtag aagttgaaca
     4801 ttatgattta ggtggagcag atccaaatgc agctgatatt tggattgttg gtcgtgatct
     4861 agctgattca gctagtcatc ttggagatgt tcgtatctta aatagtatta ttgatatgga
     4921 tgaactacga gaattaatta ctaaactttg tgaagaaaaa ggacttatat aggaggctag
     4981 cgttatgatg aagttcatat tggatattgt tagtacacca gctattttag tagctttaat
     5041 tgcaatttta ggattagttc ttcagaagaa gaaattacct gatattatta aaggtggaat
     5101 taagaccttt gttggtttct tagttgtatc tggtggtgca ggaattgtac aaaattcttt
     5161 aaatccattt ggtaccatgt ttgagcatgc ttttcattta tctggcgttg tgccgaataa
     5221 tgaagcaatt gtagctgtag ctttaacaac atatggctca gctactgcac tgattatgtt
     5281 tgcaggcatg gtgttcaata tcttaatcgc tcgttttact cgatttaaat atattttttt
     5341 aacagggcac cacactctat atatggcatg tatgattgcg gtcattttat cagttgctgg
     5401 ctttactagc ttgcctctta tcttactagg aggattagca ctcggtatta ttatgagtat
     5461 ttccccagca tttgttcaaa aatatatggt tcaattaact ggaaatgaca aggtggcttt
     5521 aggtcatttc agttctttgg gatattggtt gagtggtttt actggtagcc ttatcggtga
     5581 caaatcaaaa tcaacagagg acattaaatt tccaaagagt ttagcttttt tacgtgatag
     5641 tactgttagt atcactttat ccatggcagt tatttacatt attgtagcta tctttgcagg
     5701 gtcagaatat atagaaaaag aaatcagtag tggtacaagt ggtctagttt atgctttaca
     5761 attagcaggt caatttgcag caggggtatt tgttatttta gcaggtgttc gccttatttt
     5821 gggcgaaatt gttccagcct ttaaaggtat ttcagagcgt cttgtaccta attcaaaacc
     5881 tgctttggat tgtccgattg tttatactta tgcacccaat gcagttctaa ttggatttat
     5941 ctctagtttt gttggtggtt tagtaagtat ggcaattatg attgcttcag gaacggttgt
     6001 tatcttacca ggtgttgtgc ctcatttctt ctgtggagcg actgcaggtg tcattgggaa
     6061 tgcatctggt ggtgttcgtg gagccactat tggagcattt ttacaaggta ttttaatcag
     6121 ttttcttcca gtctttttaa tgccagtttt gggaggactt ggtttccaag gatcaacttt
     6181 ctcagatgca gattttggtc tatcaggaat tattttagga atgttaaatc aatttggctc
     6241 acaagcaggc attgtgattg gtcttgttct tattctagca gttatgtttg gagtatcctt
     6301 tattacaaag ccatctgcaa aggaggaata agggatgatt ttaagtaaaa atagggaaga
     6361 tgagttaaga aaatttgcga ctaacatccg attaaatact cttagaacat tgaatcatct
     6421 tggattcgga cattacggag gaagtctgtc tatcgtagaa gttttagcag tgctttatgg
     6481 tgaaataatg ccaatgactc cagaaatatt tgcagcacga gatagagatt atttcatatt
     6541 atcaaaaggt cacggaggac cagctctata cagtacactc tatttgaatg gtttctttga
     6601 caaagaattc ttatattctt taaatacaaa tggaaccaaa ttaccgtctc atcctgatag
     6661 aaatctaacg ccaggcatag atatgacaac gggctcttta ggacaaggaa ttagtgttgc
     6721 aactggactt gcatatggtc agagaataag aaagagtccc ttttatactt atgctattgt
     6781 tggagatggt gagttaaatg agggacaatg ttgggaggct atacagtttg cttctcatca
     6841 acagttatcc aacttaattg tatttgttga tgataacaaa aaacaattag atggttttac
     6901 aaaggatatt tgtaatccag gtgatttcgt agaaaaattt tcagcatttg gatttgaatc
     6961 cattagggtc aagggttcag atattagaga aatttatgaa gggattgtcc aattaaaaca
     7021 gtcaaataat tcatcaccta agtgcattgt attagatact attaaaggtc aaggggttca
     7081 agagctggaa gaaatgaaat ccaaccatca tcttcgccct actgtagagg agagacaaat
     7141 gttaacttca gttgtagaaa gattaagtca ggaattggag gaaacagaat gatgagaagc
     7201 acgaaagaat tacggcatgt atatagagac ttccttttag aggctaatca aagttattct
     7261 gatatagtag tcttagaagc cgatttgtca agttcgatgg ctactaataa tcttgaaaag
     7321 gattttggag accgttatgt gaatgttggg attatggaag cagaaatggt cggccttgca
     7381 gcaggcttgt ctattcaggg gtttagacct tatcttcata catttggtcc ttttgcttca
     7441 cgaagagtat ttgatcaatt atttatttct cttggatacg cacaattgga tgccactgtg
     7501 attggatcag atgcaggagt aactgcagaa atgaatggtg ggacacatat gccatttgaa
     7561 gaaattggat tgttacgttt aattcctaaa tcgatcattt ttgaagcaac tgatgatatc
     7621 caatttcgtg aaatattgaa ccagacatta gacttaaaag gactaaaata tattcgaaca
     7681 attagaaaag ctccagttcc tgtgtatcaa ggtggagaag atttttctaa gggctacatt
     7741 gagttaaggc atggtgaaga tcttgtaatc gttgcttctg gtataatggt tgctccaagt
     7801 attcgagttg cagatgaact gtctaaatta ggttattcag taagtgtgat agatttattt
     7861 agaatcaaac cgataccaga acagataaaa acaatgttaa gtggaaaaac tatatttact
     7921 gtagaaaacc acaatcagat aggtggaatt ggcagttctt tatgtgaatt attctctgat
     7981 gatggaatga caaaaattca tcggatgggt gttcaagaaa gattcggtca agtagggaaa
     8041 atggattatc ttcttaatga gtatggtttg agtgaatcga atataaaaga gaaggttcta
     8101 gaaatttata atgcaagata gatgttaaat acacttatct gaaagaattt ctgtaaaaat
     8161 tacagtacgt tatttaaaga aagcggatta aaaagcatat tctggtcatc agaaagtgca
     8221 ctaatccgct ttgttgtttt taattttaaa tatttcacat gtgtatagaa ttttctgaaa
     8281 attcaagatt tttattctgt tcttcatgcg aaaattgtgc tataatagta aaaactgaaa
     8341 tgggagggat aagatgactg aattagataa acgtcaccgc agtagcattt atgacagcat
     8401 ggttaaatca cctaaccgtg ctatgcttcg tgcgactggt atgacagata aggactttga
     8461 aacaccgatt gtgggagtga tttcgacttg ggcggaaaat acaccatgta acattcactt
     8521 gcatgatttc gggaaactgg ctaaagaagg tgtcaaatct gcaggcgctt ggcctgtaca
     8581 gtttggaacc attaccgtag cagacgggat cgctatggga acgcctggta tgcgtttctc
     8641 tctaacatct cgtgacatca tcgcggactc catcgaggcg gctatgagtg gtcacaacgt
     8701 ggatgccttt gtcgctatcg gtggctgtga caagaacatg cctggatcta tgattgctat
     8761 tgctaatatg gatatcccag ctattttcgc ctatggtgga actattgcac cgggaaatct
     8821 tgatggtaaa gatatcgact tggtttctgt ctttgaaggt atcggaaaat ggaaccacgg
     8881 tgacatgaca gctgaggacg tgaaacgtct tgaatgtaat gcctgccctg gccctggtgg
     8941 ctgtggtggt atgtatactg ctaataccat ggcaactgct atcgaagttc tagggatgag
     9001 tttgccaggg tcatcctctc acccagctga atcagctgat aagaaagaag atatcgaagc
     9061 agcaggacgt gctgttgtta agatgttgga acttggtctc aaaccatcag atatcttgac
     9121 tcgtgaagcc tttgaagatg ctattactgt aacgatggct ctcggtggtt ctacaaacgc
     9181 cactcttcac ttgctcgcca ttgcccatgc cgcaaatgtt gacttgtcac ttgaggactt
     9241 caatacgatt caagaacgtg tgcctcactt ggccgacttg aaaccatctg gtcagtatgt
     9301 cttccaagac ctctacgaag tcggtggtgt ccctgcggtt atgaagtact tgttggcaaa
     9361 tggtttcctt cacggagatc gcatcacatg tactggtaag actgtagctg aaaacttggc
     9421 tgactttgca gacttgactc caggccaaaa agttatcatg ccacttgaaa atccaaaacg
     9481 tgcggatggt ccgcttatca tcttgaacgg gaaccttgct cctgacggtg cagttgccaa
     9541 ggtatcaggt gttaaagtgc gtcgtcacgt tgggccagct aaggtctttg actcagaaga
     9601 agatgcgatt caggccgttc tgacagatga aatcgttgat ggcgatgtag tcgttgttcg
     9661 ttttgttgga cctaaaggtg gtcctggtat gcctgagatg ctgtcacttt cttcaatgat
     9721 tgttggtaaa ggtcagggag ataaggtggc cctcttgacg gacggacgtt tctctggtgg
     9781 tacttatggt ctggttgttg gacatatcgc tcctgaagct caggatggtg gaccaattgc
     9841 ctatctccgt accggcgata tcgttacggt tgaccaagat accaaagaaa tttccatggc
     9901 cgtatccgaa gaagaacttg aaaaacgcaa ggcagaaaca accttgccac cactttacag
     9961 ccgtggtgtc ctcggtaaat atgcccacat cgtatcatct gcttcacgcg gagccgtgac
    10021 agacttctgg aatatggaca agtcaggtaa aaaataaact catactcgaa aatctcttca
    10081 aatcacgtca acgtcgcctt gccgtaggta tggttactga cttcgtcagt tctatccaca
    10141 acctcaaaac agtgttttgg gctgacttcg tcagttctat ccacaacctc aaaacagtgt
    10201 tttgagctga cttcgtcagt tctatccata acttcaaaac agtgttttga gcaacctgcg
    10261 gctagttttc tagtttgccc tttgattttc attgagtatc aaaaagcaag ccattttcgg
    10321 cttgcttttt tcatctttaa aagtgattgg cctgcttaac gaggtggtag tccaagggca
    10381 atacggccat agcgactgat tcgtgtgatt ttccaagcag gcgaccaggt aacttcaacc
    10441 ttgatatctt tgataccctc gatttgtttc agacctgcca caatttcaat aggcaggctt
    10501 tcggcgcaat cacaggcagt atcggtgaag gtcatgacaa tcttgcagag ccccgtttca
    10561 tccagattga tttcataaat cagacctaga ttgtaaacat ccaattccac atctgtatca
    10621 aaaactttct ctagtttttc gataatttgg tcttgcaagg ccaaagcacg gtcattgatt
    10681 ttgatatcgt ctctcatagc agtccctcca cgtgataaat atcctctatt ttctcataat
    10741 tctgacaatt tggcaagttt ttgatgaatt ttctgaaaaa taggataaaa tgaagaaaat
    10801 acggaatcaa ggggaagtct atggagcaga ttggaaaagt ctttagacaa ttacgagagt
    10861 caagaaatat ctcactgaga caagcaaccg gaggacaatt ttcgccgtct atgttgtccc
    10921 gttttgaaac aggtcagagt gagctttcgg tggaaaagtt tctatttgct ctggaaaata
    10981 tatctgccag tgtggaggag atcctctttc tggcgagagg tttccagtat gatacagatt
    11041 ctgagttgag aaaagaaatt acagatgtct tggaaccaaa gaatatagca cctcttgagg
    11101 acttatatcg cagggagtat caaaagcatg cccattctca caacaaacag aaacatattc
    11161 taaatgccat tattatcaag tcttatatga agagcatgga tgaaagggta gagttaacag
    11221 cagaggaagg aaaagtcctt catgattatt tgttttctac cgagatctgg ggaatctatg
    11281 aactcaattt attttcagtc agttctccat ttttatctgt ttctcttttt actagatatg
    11341 tacgagaaat ggtacgtaaa tctgattttc taatggaaat gtctggcaat cgaaaccttt
    11401 ttcatactat actattgaat ggctttttag ctagtattga gtgtgaagaa tttaccaatg
    11461 cctattattt taaacgtgtt atcgaagagc atttctacaa ggaaaatgag acctatttcc
    11521 gaattgttta tctgtgggca gaaggtctcc ttgatagcaa gcaaggtaga gtcaaggaag
    11581 gccagaaaaa gatggaggat gctgtccgta tttttgagat gcttggctgt aataaatctg
    11641 ccgaatacta tagaaatacg accgaatgtt gaatatctgc aaaccaagaa aaaatttgaa
    11701 gcgatagaac tattgccctc tctcaggtca ttacaaaagt tctatcgttt ctttttgctc
    11761 attttatttg ttgcatatat tcaagagttc tccctctcaa atttctaagt gctatactat
    11821 agtcatactt catatagagg ttcgaacaag aagggagatt atctatgaaa ctattgttta
    11881 gaaatccagc ttatagaatt ttgattttat cacgcttctt caatgctttt ggtgcttcga
    11941 ttttcaacct ggtctttatc gtctatgcat cgaccttgtc acaagcatct tttgctgttg
    12001 ctatggcgaa tattgtcatg attcttccga ccctctttac agtttttgta gggattcggg
    12061 cagattacac gagggacaag gtcaaatgga tggtctatag cggtttgttt caggcggttc
    12121 tattttttct agcagcccta gttgttcagc aagctagtct ctttgccttt tctagcctgt
    12181 gtttgatcaa tgtcattagt gatatcatca gtgattttgc aggtggcctg cgtatgcctc
    12241 ttattaagga aaaagtagct gaagatgatt tgatggaggc ttattctttt tcacagttca
    12301 tcacctatat ttcagctatt ggtggtcaag ctttcggagt ctggctctta gctctatcgg
    12361 tcaacaattt ttctctcgtt gcgggaatca atgcctgctt tttcctagta tcagccacta
    12421 tcctcttttt aggaaaaagc aaattgagcc tgtcaatgtc atctgctgat ggtgaaaact
    12481 taaaaaatga gaagctttct atcaaagacc agttcctaac aatttaccga aatttacgtc
    12541 tcgtttttct taaaagtggg cagaaaaact ttggttttat gctctttgct gtcttgctta
    12601 ttaattcctt gggtggcgct ttgggtggaa tttataatat cttctttttg agccattctc
    12661 tcttgaattt ttcttataca gaggcactat ttatcaatca attctgtgtt ttagtagcaa
    12721 tcatcatcag tagccttacg ggcaatgatt attttgggaa gcagtccttg cctagattga
    12781 tgatgtgggc gaccgtagga cttagtctag ttggtttggc taatttattc aatcaagtcg
    12841 tgcttggttt gctatttctc ttctttaccc tgtatgtgtc tggtaaagtt caaccaaaga
    12901 ttagtgccat gctcatgaaa aatctagctc cagaggttct agctcgtact agtaattttt
    12961 taggtctatt gtttacctta tccatacctg tgggaacagc ttgtttttca ctagtagccg
    13021 tatggaatat acagttgact tggatgctat ttgttggtct ttccttgcta gctatttttt
    13081 tgacaattct taatctcaaa aatgatatct aaatcctaat ttttttctta ctgttttaat
    13141 ccctttattt gtggtaaaat aagactatta agtttaaaga ggattcccta tgaaattaca
    13201 aaaaccaaaa ggaacgcagg atattttacc tgctgaatct gctaagtggc agtacgttga
    13261 gggctttgcc cgtgagattt tcaagcgcta taactatgca gaagtgcgca cgcctatttt
    13321 tgagcattac gaggttatca gtcgctctgt cggagataca acggatatcg taaccaagga
    13381 aatgtacgat ttttatgaca agggtgaccg tcatattacc ctccgtccag aaggaactgc
    13441 gcccgttgtc cgttcctatg tggaaaataa actcttcgcc ccagaagtgc aaaagccaag
    13501 caagttctac tatatgggac ctatgttccg ttatgagcgt ccacaggcag ggcgcttgcg
    13561 ccaattccac caaattggtg ttgagtgttt tggctctagc aatccagcta ccgatgtgga
    13621 aacaatcgct atggcagccc attttttgaa ggaaatcggt attcaaggtg tcaaattgca
    13681 cctcaacact cttggaaatc ctgagagccg tgcagcctac cgccaagcct tgattgacta
    13741 tttgacaccg ctcaaggaga ccttgtctaa ggatagccaa cgtcgcttgg aggaaaatcc
    13801 tcttcgtgtc ttggactcta aggaaaaaga agacaaggag gcagtagaga atgcgccgtc
    13861 tatcttggac tttcttgatg aagaaagcca agctcatttt gatgctgtgc gtcagatgtt
    13921 ggaaaatctt ggagtagatt acatcatcga taccaatatg gtgcgtggtc tggactacta
    13981 caaccacacc attttcgagt ttatcacaga gattgagggc aatgacctga ccgtctgtgc
    14041 gggtggtcgt tacgatggtt tggtttctta ttttggaggc cctgaaactg ctggatttgg
    14101 ttttggactt ggtgtagagc gcctgcttct cattcttgaa aagcaaggtg tgaccctccc
    14161 tatcgaaaac gccctagatg tctatatcgc agtcttgggc gaaggggcaa atatcaaggc
    14221 cttggaattg gtacaggctc ttcgccaaca aggtttcaaa gcagagcgtg attacctcaa
    14281 ccgtaaacta aaagctcagt tcaagtcagc cgatgtcttt gtggctaaga ccctcatcac
    14341 cctaggagag agcgaagtcg aaagcggaca agtgacggtc aagaacaacc aaactcgaga
    14401 agaagtgcaa gtgtcacttg agacaatcag ccaaaacttc tcagaaatct ttgaaaaact
    14461 aggattttat actcaataaa aatcaaagag caaactagga agctagccgc aggttgctca
    14521 aaacactgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaaca tggttttgag
    14581 gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggtgaa gctgacgtgg
    14641 tttgaagaga ttttcgaaga gtattaatga tagataaagt ggtcaggaac ttactcctga
    14701 cctttttctt ttgcaaaatg acaaaaatca taaacttttt gacaaatata cttgtcaaaa
    14761 agaaaaagat atgttacaat gaattcaagt taagaaatag gaagcagaaa ggagttataa
    14821 tgtgggtact aggatttata ctatttatga ttttctttta ttctaataat tctaaaaaaa
    14881 tcaagaaact agagaataaa atcaaaaaac ttgagcgaaa agagaaagga aacgcagaaa
    14941 tgtcgagatt attacaagaa atgattggaa aggaaccaat tataacggga gtgtatattg
    15001 ggccagataa ctgggaagtt gtggatgttg atgaggaatg ggtcaaacta cgtagtgttg
    15061 ataatacggg aaaagaaaaa ttcaagttgc aacgtattga agatatccaa accgttgaat
    15121 ttgacggaga gtaggtgtgt aacgtgcaac taaaaaatcg tctaaaagag cttcgagctc
    15181 gcgatggtct caatcaaacc gacctagcca aactggcagg ggtttccaga cagaccatta
    15241 gcctactaga acgggatgag tacaccccat ccattatcat tgccctgaaa atatctcaaa
    15301 ttttcaacga aacagtcgaa tcggtatttc gtttggagga ggacgagtga tgaacaagta
    15361 taaagtgatt tattatgtag tggtcatagc tttattagtc agcgtatttc tactgattgg
    15421 gatggaccta agctggttta atccctatca aggcgaccaa tttgtttggc tctactttgc
    15481 tctcatccca gtaattgaat ggattgaaaa gaaatccaaa aatctagcaa gtgaaaaagg
    15541 agaatgaata tgaaaaagaa acgtagattg ttatttttga tgtctattgt cttggggggg
    15601 ttcttgggca tgtttgtagg gatgtttaag gcacgtgtcg aatcccacga aattatttta
    15661 gatgtaaaag ccttgatgcc atggatatca gctatttgtt tactgatagg tttcattagt
    15721 atgtttttga ctttcaattt cttaaagaaa agcagaaaat ttcattcctt gtatcaagag
    15781 gaaatggatg acgatctgaa tgaaacctat tatgtgcaaa tgtatcggaa tcttgagttt
    15841 ggaaccattg cttttaatat tacaggtgta gcgattccat tggctatttt tatttcatta
    15901 agtgaggtga ttatattgca tacaaaccct caaacatttt tcctttcttt cttactcttt
    15961 gtggtattct tagtcgctca aaaatctctt tttaaaacca ttgcgattgt tcgtcagttt
    16021 gatttggaat ttttcgctac accaaaggat gtcttgaact atataaattc ttatgatgaa
    16081 ggggagcgtc aggctaattt ggaacagagt tttcgaattt tattccaatt acaccaatat
    16141 gtcttaccag ccttatatat ttttcttatt atcatttctt tcttgacagg agagattcag
    16201 ttactagctt tcttgcttgt aggagccatc catgtttata tcaatgtgat gcagttacct
    16261 atggtaaaac gttatttcaa ataaaggagt tatctatgaa attacttaaa aaccttggct
    16321 ggattcttct agcccttcta tcctttttat ttatctatgg ctttattcag gggctcgcga
    16381 ctgcgtcgct tgctttaggc gcttcaccct atgctgttac tctactctat gtggccttgg
    16441 ctggagtata tgtgtacggc atttacaaat ggtatcagaa ggctcctgtt catattgaga
    16501 agagcggctt taaccgattt atttggcttc ctgccttggt ttggttctta tctctggtcg
    16561 ttcaattctt cttgccagat gatccttcag taaatcagca aatagcgaca gacttgacct
    16621 tgtctcaacc acttttctca ttctttgctg tggttatttt tgctcctttg acggaagaga
    16681 ttgtttttag agggatgtta gcacgctatc tctttcctaa gcaggacaat agtaaacgaa
    16741 ccctgatttt tcttctggta tctagtcttc tatttgcctt gattcatttt ccaggtgatg
    16801 tgcaacaatt ttttgtctat tttagccttg gttttagttt gggcttggct tacattagca
    16861 gaaaaggtct ggtctacagt atttctcttc acgctttgaa taatttagtc ggctttttga
    16921 tgattctcat gctataatag agtcaggagg tcacatgaaa cgagtaattt tattagcagt
    16981 gattcaggca gtcgttctat ttttcatcat tggagcgcta gcttatgcct tcaaaggcga
    17041 tttcttctat aactatctag cagttgtctt tgctcctatt gcaggtgtac tgcgttttgg
    17101 gacggcttac ataacggaaa ttgtcttgcc tcgaaaggca gccgaaatcg ctgaaaagcg
    17161 taaagcaggc aaaaattcaa aataaaagag tccggtgaag ttcatcggat ttttgtatta
    17221 tactcaatga aaatcaaaga gtaaactagg aagctagccg caggttgctc aaaacactgt
    17281 tttgaggttg tagatgaaac tgacgaagtc agctcaaaac atggttttga ggttgtagat
    17341 gaaactgacg aagtcagtaa ccatacctac ggtaaggcga cgctgacgtg gtttgaagag
    17401 attttcgaag agtattagcg ctaattttta gggctttcac ttgactttta aagactggca
    17461 aacttttctg atgattttca tgaagagcct gcgcttttat ggtaaaatag taacagaata
    17521 aaagaggaga gaaataatga aacgtagtat gtatgctggt cgtgttcgtg aggaacacat
    17581 cggacaagaa ataaccttga aaggatgggt tggccgtcgt cgtgaccttg gtggtttgat
    17641 ctttatcgat cttcgtgacc gtgaaggaat catgcagttg gttatcaacc ctgaaaaagt
    17701 atctgcagag gttatggcaa cagctgaaag ccttcgtagc gaatttgtta ttgaggtgac
    17761 tggtcaggtc gctgcgcgtg agcaagccaa tgataagttg ccaactggtg cggttgagtt
    17821 aaacgtgaca gctcttattg tgcttaacac agctaagaca acaccatttg agattaagga
    17881 tggcattgag gcaaatgacg atacacgttt gcgttaccgt taccttgacc ttcgtcgtcc
    17941 agaaatgttg gaaaatctta aacttcgtgc caaggtgacc cactctatcc gcaactattt
    18001 ggatgagttg gagtttatcg acgtggagac accattcctt tctaagtcaa cgcctgaagg
    18061 ggcgcgtgat tatttagtgc cgtctcgtgt taataagggg catttttacg ctcttcctca
    18121 aagtccacaa atcacgaaac agctcttgat gaatgctggt tttgaccgtt actaccaaat
    18181 cgttaaatgt ttccgtgacg aggacttgcg tggagaccgc cagcctgaat ttactcaggt
    18241 cgacttggaa acgtccttcc ttactgagaa agaaatccaa gatattacag aaggcttgat
    18301 cgcgcgcgtg atgaaggaaa caaaaggcat cgaagtaacg ctaccgttcc ctcgtatgaa
    18361 atacgatgat gctatggctc tttacggttc tgacaagcca gatactcgtt ttgacatgtt
    18421 gcttcaggac ttgacagaag tggtcaaagg tgtagacttt aaagtctttt cagaagcacc
    18481 tgctgtaaaa gcgattgtgg tcaaaggagc tgcggacaac tattcacgta aagacatcga
    18541 caagatgacg gaagtagcca aacagtatgg tgccaaaggt cttgcttggg tcaaggtggt
    18601 tgatggagaa ttaaacggac cagttgccaa gttcttgact ggtatccaag aagaattgac
    18661 aacagcgctt gctcttgaag ataaggactt ggttctcttt gtggcggata cgcttgaagt
    18721 ggctaatgca acactgggtg cccttcgtgg acgtattgct aaagagcttg gcttgattga
    18781 taatgataag ttcaacttcc tttgggtggt tgactggccg atgtttgaat ggtctgaaga
    18841 agaaggccgc tacatgagcg cccaccatcc attcacactt ccacaggaag agactgctca
    18901 cgaattagaa ggtgatttgg ctaaggttcg tgccattgct tacgatatcg tcttgaacgg
    18961 ttatgagctt ggtggtggta gccttcgtat caaccaaaaa gaccttcaag aacgcatgtt
    19021 caaggctctt ggtttctcaa ctgaagaagc caatgaccag tttggtttcc ttcttgaagc
    19081 catggactat ggtttcccac cacacggtgg tttggctatc gggcttgacc gttttgtcat
    19141 gttgcttgct ggagaagaaa atatccgtga agtcattgcc tttcctaaga acaacaaggc
    19201 aactgaccca atgacacaag ctccatcaac agtcgctctc aaacaactag aggaactcag
    19261 cttacaagta gaagaagatg aaacaaacaa aacgaattaa gcggtggcgc tattatctgc
    19321 gccgctttgc ttatcagata aaaattttac gtgtcttaca aagtatctct cgagaaaagt
    19381 atgatgagaa gatttcggcc tctctggtct atggtttttt atcagcagta gcagttaatt
    19441 tctttttcca accagggcat gtgtattcga gtggtgcaac aggtctggca cagattatct
    19501 ctgccttgag taatcactgg tttggttttc atattccgat ttcgctaagc ttctacgcca
    19561 ttaacttccc tttgatggtc ttagcttggt atcagattgg ccataagttc accgtcttta
    19621 cctttatcac ggtatctatg agttccttct ttatccagtt tgtccctgtg gcaaccttga
    19681 cggaggatcc cattatcaat tccctttttg ggggtgttgt tatgggtttg gggattggtt
    19741 ttgctcttcg aaacaatatc tccagtggtg ggacggatat cgtcagcctg actattcgca
    19801 agaaaacggg taagaatgtc ggtagtattt ctttcttggt aaatggaact atcatgctga
    19861 tagcaggttt gacctttggt tggaaatacg ctctttattc tatgattacc atctttgtct
    19921 ctagccgtgt gacagacgca gtctttacta agcaaaagcg tatgcaggcc atgattgtga
    19981 caaatcatcc agagaaggta attgaaaaaa tccataaaaa attgcaccgc ggagcaacca
    20041 tgatccacga tgcagaagga acctataatc acgagagaaa ggcagtttta atcactgtca
    20101 ttacacgtgc agagtttaat gaatttaaac agattatgac acaagtggat ccaagctcct
    20161 ttgtctctgt ctcggaaaac gttcatattc taggaagatt tgttgagata gataattagt
    20221 gattaatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtatatatgt
    20281 tactgacttc gtcagttcta tctgcaacct caaaaccatg ttttgagctg acttcgtcag
    20341 ttctatctgc aacctcaaaa ccatgttttg agctgacttc gtcagtttca tctacaacct
    20401 caaaaccatg ttttgagctg acttcgtcag ttctatccac aacctcaaaa cagtgttttg
    20461 agcaacctgc ggctagcttc ctagtttgca ctttgatttt cattgagtat aaaaagatct
    20521 tgggaaaaga ctcaatttca gtagaaaagg aagtaaatct tcccacaata aaacgcatag
    20581 tatcaagttt tttcaatacc tgatagtatg cgtttttgct tttaacgact ctttgcccag
    20641 tctcttattt ttcgataatt ttgtgggcga tcaattgacg gtaacaaatt tgtttattgt
    20701 ttttattatc attaataatc tggagaatag tttcaaggga aacacgacca agctctaaac
    20761 tattgatatc gacataggct gccaagttga gcttgggatt aaccgagtca aagctgagaa
    20821 cagggacatc cagctggtgt ttggcaatat agttacaaac accttcagct aggaggctat
    20881 cggttgtgat gatagcatca atttgtggat cgtgcttgaa taatcgcttg ctaaatttat
    20941 agcccttttc ttccagaaac tcgtcggcaa agtagatgcg attgttgtca gtggtaagtt
    21001 tgtaatgttt aagcgcctgt tcatagcccg ttaaacggtc tttggtcacg aagagctttt
    21061 tacttcctcc gataaaggca atgcgtttgc agcctttttt gatgaaatat tcagtcgcat
    21121 caaaaccagc ttgaacattg tcgttgtcga caagtgggat gaaaggagat agagatttac
    21181 ctaagataag gaaggggaac tgttcttctg cgacgagttt tacgagaggg tcttcttctt
    21241 gggcatagag aaagattagc ccatctacac gcttgccgta gaccatttgt gaaatagcgt
    21301 tgagacgctc cttctcatct ttccctgttg ctatttgaat ggcatagtgg ttttcagatg
    21361 cgacttgaga gatgccacgt agaaccgatg gaaagaaagg attctggtag aaggcgtctg
    21421 agtcatcagg aagaactaat ccgataacct gagtatagct gcttaccaag ctacgagcgt
    21481 taaggtttgg gtggtagttg agttccttca tagctttgcg aacgcgtttt tttgtttcgt
    21541 cgctaatggt tgatttattt tgaataacac gggttacggt tgaaggcgaa acaccagcag
    21601 ccttggccac gtctttaatc gtaacgggca taaaaatctc ctatttatgg taatttggat
    21661 cacggaaatg tgttttataa aagatagtga ccagatacag aacaaaaaga atattttgta
    21721 cagtaatcag ggttgtcata ttttggccaa ataatcccaa aataagtgta atcagagtcg
    21781 gcaatcctaa acagttcaag ataaagtgat agcactcttt aaaggttcta aatgaaaaga
    21841 ggcgtgattt cttagtgata taaaggagaa gactagctcc tagagagacg ataaagaaat
    21901 tcaaaccaaa gaggaagctc gcaccgagaa ctaggaagag gctgatatag acacgatttt
    21961 gttggtacca gtctttagaa attgcttggg tcaagctgtc tttgcttttg aaactctcag
    22021 tctgaatggc tcggtaagag atgcgggtca gttccttgct ttccttgctg atgactagtt
    22081 catttgtatc gaaatgcagt tgcaagtcct taggtaattc cttgatttga cctggaccaa
    22141 tcacaacaga aggggcttga ctagctgttc cagtataagt taatgtgcca tcgacaattg
    22201 tagcatgttc agagagatcc tggacaacct catttgtcag aggttcatag acattatcga
    22261 taaaagtttc tagcggatag gtctcctggg agctgttttg gatagcaatg ggtaccatag
    22321 acaagctgat aaggaagata ctggtaaaga gaagttgaaa ccagttgagc tcgaaacgtt
    22381 tggacagggg cttacgaaac ccccaaatac ttgaaaaata ggaaaatgga tatggaagca
    22441 taggtatctt tctaaaaggt gttttctata tgagtattat tatatagaga aatgcgcttt
    22501 atttcaagtc tagggggtaa attgcttgct acaaggatat tatttacagt gacaatcgct
    22561 aatagtcaat gaaaatcaaa gtgcaaacca ggaagctagc tgcaggttgc tcaaagcaca
    22621 actttgaggt tggagataaa gctgacgtgg cttgaagaga ttttcgaaga gtataaaatg
    22681 aaaaagggtg gcggggataa attatccctt gtcgccacca cttgtaagtc ctgaaacaaa
    22741 gttcttttgt aggaagaaga agagaataca gattggaagg gcgatgagga tagcacctgc
    22801 tgagaagtag gcaatcttca agtttttcgc attgttaacg aaggtttgga gacctacggc
    22861 aacagtaaag tattctttct cacgaagcaa gaaactagag aggatgtagt ccccgaaagg
    22921 tcccatgaag gcccagagag cttgtacggc aaccattggg cgaacaagtg gtagaacaat
    22981 ttgccagaag cggcggaagt gtcctgcacc gtctagtttt gcagattcgt ctaaagacat
    23041 tggcactgta tcgaagtagc ctttcatgag ccaagcattc atcgggatac caccaccaac
    23101 gtagaggaag atgaggaacc agttgtggtt aagggcgttc aacataagcg ccataacgaa
    23161 gaaggctgtc aaagcggcca tagttggcac catttggatg atcaagaaga agaccaaact
    23221 ttgtttacga gccaagaagt tgtaacggct gtaagcataa ccagcaagta cgatgatact
    23281 tgtttgaaca gccatggtaa ttaaggcgat aatcaaagtg ttgaggtacc aagtaccgta
    23341 caaggtttca gtgaagaggc ctttaaagtt atcaaaattg aggtcgatat tagtatctag
    23401 tttaaaggct gagacgttac ctgctttaaa ggctgacatg atggtaatca acagtggata
    23461 gataattaca attgatagac caatcaggta aaggtaagta aggctttgag tcagtctacg
    23521 tttgagttta attgagttat tcatcttaga cgtcctccat atcaaatgcg tgtagtttct
    23581 tgaatgcgat catagagatt gagatgacaa tgatagagat aatcaaggta acagctgccg
    23641 ccattgagta ttgaggagat gtacctgttg tcaaacggta gatccatgag atcaagatat
    23701 cggttgaacc agctccacct ccgacactac caggtcctcc accattgaag aggtacatga
    23761 tagagaagtt gttaaagttg aaggtgtatt ggctaatcaa agtaggtgcc gcaacagcca
    23821 aaatcattgg gaaagtgatg ttgcggaatt tttgccaagc gttggcaccg tcaatataag
    23881 ctgcttcgta aaggtcgtta ggaatagatt gcaagatacc caaagtcaaa acgtagatgt
    23941 atgggaatcc gagccaacct tgcatcataa tcaaggcaat cttagtccaa gttgggtctg
    24001 ttttccaagg aataagagct ccatcaagga aaggaaggaa tttagccaag attggcaata
    24061 cttgagtgtt gatagcaccg acactatcgt taaacatgtt tgagaatgtc aagatagtga
    24121 tgaaggctgg gacagcccaa ggaagaagga aaataacacc aaagatacgt tttcctttga
    24181 taaatggttg gttggcaatg atagctgtga agataccaat tacgatttgt aaagtagaag
    24241 ctgccaaagc ccaaatgata gtccaagaaa gaacagaacc aaaggcagaa cggaaggtac
    24301 tcaagctcca aatgtttgta aagttggtca aaccaaccca gtccaacaac ttgtttggtg
    24361 gcaagtgttg gaagtcgtag ttggtaaagg cgatcatcaa ggttacgata actgggaaga
    24421 taatcgcgaa ggtcatggca acataagatg gaatgatcaa gaggtaaggg aagccatttt
    24481 cataaatccc tttgatcatg tctttgagtg tgcgtggaac tggaattcca ttgttaatgc
    24541 gttttgcaat cgtatgtgca tctttgatat ttgagaaata aaagagtaca taaacgatta
    24601 caaagattag atggaaggca ccacgaatca gcataaagag ggaattatca cgacctggtt
    24661 tgtcaccaag agtgatgagg ttgctcaatt caggggttgc aagtgctagg aagtaaagga
    24721 caaatacgat ggttacacca aggaagataa aacctttggc tttttgttta ttgtaaatct
    24781 gtcctaaccc aggaatgata gacagcaggg ctgctttact aggttgttgc ttttccatat
    24841 taactccttt cataggatac tactttttta taagaaagct aaattatttg tgtctctatt
    24901 gataaattca aagggggatt tgatttccac cccccttgaa caaatttttt attcaccaaa
    24961 tttttgtttg attgtttctt tgatcaatgt tacagcatcg ttagcagctg ttttagcatc
    25021 tttttgacca cttacagcat caaagagcat atttttcgct ggatcccaaa ctgcagacat
    25081 ttgagagatg tttggcagtg gttgagtgtt cttgaactgt ttgataacag ctgttgtcaa
    25141 ctcatcgttt ttaccttcag cgtatgaacg agcctcagta ttagctggga tttcgttagt
    25201 cttatcatat aatacttttt gttgttcagt tgcaacaagg aagtctacaa atttttgaga
    25261 agcttcaagg ttcttaacgg cttgaggaat gacccaagct ttaccaccac cgaatgcagc
    25321 atattctttt ccatttggaa gagttgggat agttgcaact ccgtagttta ctttagcatc
    25381 tttaaaggct tgagctttcc aaggtccgtc gatgatagca gctgttttac cttcttggaa
    25441 ttgagtttgg attaagtttc cagcaccttc tgtatcttgc atacctttag gccatttttc
    25501 gtaccaagat ttagcgtagt tgatacctgc gatagaaccg tcgtttgcaa gaccgatgtc
    25561 tttagcgtct ttaccgtttt ggccaaagac gtaagcaccg ttaccggcaa gaagtccata
    25621 tgtatagtag aagtttgtcc agtcagctag gaaggcagta gttttaccat cttcaccagc
    25681 gaatgcgtat ttgctatctt tagcaaggtt ttccaagtca gcaaatgttt ttggagcatc
    25741 tttcaccaag tctttgttgt agtacataac aagtgactcg ataacggcag gagcaccgta
    25801 aactttacca ttagcagctg ttacaagaga tttagttgtg tcgtctgttt tagcaccatc
    25861 gctcaatttc acttctgaaa gttgtccgtc agaaccaagg ctacctacac ggtcgtatgg
    25921 agccatcata acatcaggga cattaccaga ttggttgtca agagaaagtt tatcaagacc
    25981 tcctagagca tcaccagttt taagagtgac ttttactcca gcttcttttt cataagcttt
    26041 agcaacctct tcaatatagc tcttatatcc ctcgtctaca tatacagtga gttctttgac
    26101 ttcagatgaa ccagaatcag caggcttatc agcagttttg cttccgcaag ctaccaaaag
    26161 caagctagca agtgtagcag ttccaagcac cgcagtgctc ttcataaatt tagatgacat
    26221 agtgtattcc tcccaaagaa tagcaagttt tattgataag gaaacgcaaa cgttttcctt
    26281 tatgagctta gtatagcaca aatagaaaac ggttgcaagt attttttgta aaaattttaa
    26341 aaaattttta agcttgattt gatagcataa ttttgcattt taatagaaga aaagtatgaa
    26401 atagataaga atacagtatt tttaataaaa atatatggaa tctgtctaaa gagggaaatc
    26461 aggaggggct acctccctgt ttctaatccc tatctatttt ctatagacgt ttgtgctttg
    26521 ttgcatataa attcaagctc cctaaggagg ttttgtactt tgtagactgt ctcgtgagag
    26581 tcaaacttta ggattagata gttttaagtt atctttgcta aaatgagtta gtctccttaa
    26641 aaataatcaa aaaagttttt taaaaacgct tgcaattatg cttgaaaagg agtatactta
    26701 taagtaacgc aaacgtttgc gtctgcaaaa tacgcaacgt tccattattt taacacacga
    26761 ggtgctatta tgaaaaaacg tcaaagtggt gtgttgatgc acatctcttc tcttccagga
    26821 gcttacggaa tcggatcatt tggtcaaagt gcttacgact tcgttgattt cttggtccgt
    26881 acaaaacaac gttactggca aatccttcca ttaggagcaa ctagttacgg ggattctcct
    26941 taccaatctt tctcagcctt cgcaggaaac actcatttta tcgatttaga tatcttggtg
    27001 gagcaaggtt tgttggaagc aagtgacctt gaaggagttg actttggtag cgatgcgtct
    27061 gaagttgact atgctaaaat ctactatgca cgtcgtcctc ttttagaaaa agcggtgaaa
    27121 cgtttctttg aagtcggaga tgttaaagat tttgagaaat ttgctcaaga caaccaatca
    27181 tggcttgagc tctttgctga gtatatggct atcaaagagt attttgacaa tcttgcttgg
    27241 actgaatggc cagatgcaga tgctcgtgct cgtaaagctt cagcacttga aagctatcgt
    27301 gagcaattgg cagacaagtt ggtttaccac cgtgtgactc aatacttctt cttccaacaa
    27361 tggttgaaat tgaaagctta cgctaacgac aaccacatcg aaatcgttgg ggacatgcca
    27421 atctacgtag cggaagattc aagtgatatg tgggcaaatc cacatctctt caaaacagat
    27481 gtcaatggta aggctacttg tatcgcagga tgcccaccag atgagttttc tgtaactggt
    27541 cagctttggg gtaatccaat ctatgactgg gaagcaatgg acaaagacgg ctacaaatgg
    27601 tggattgaac gcttgcgtga aagcttcaaa atctacgata tcgttcgtat cgaccacttc
    27661 cgtggcttcg aatcttactg ggaaatccct gctggttccg atacagcagc acctggtgag
    27721 tgggtgaaag gtccaggcta caagcttttt gcagccgtta aggaagaact tggtgagcta
    27781 aacatcatcg cagaagacct tggcttcatg acagatgaag tgatcgaatt gcgtgaacgt
    27841 actggcttcc caggaatgaa gattcttcaa tttgccttca acccagaaga cgaaagcatt
    27901 gatagcccac acttggcacc tgctaactca gttatgtaca caggaacaca cgataacaat
    27961 acggttcttg gttggtaccg taatgagatt gatgatgcga ctcgtgagta catggctcgt
    28021 tacacgaacc gtaaagaata cgaaacagtg gtacacgcta tgcttcgtac agtattttca
    28081 tcagttagct ttatggcaat tgcaactatg caagatttac tagaattgga tgaggcagct
    28141 cgtatgaact tcccatctac ccttggtgga aactggtctt ggcgtatgac tgaagatcaa
    28201 ttgacaccag ctgtcgagga aggtttgctt gacttgacaa caatttatcg ccgaattaat
    28261 gaaaatttgg tagatttaaa gaaataagac aataatcagg agacaactaa acatgttatc
    28321 actacaagaa tttgtacaaa atcgttacaa taaaaccatt gcagaatgta gcaatgaaga
    28381 gctttacctt gctcttctta actacagcaa gcttgcaagc agccaaaaac cagtcaacac
    28441 tggtaagaaa aaagtttact acatctcagc tgagttcttg attggtaaac tcttgtcaaa
    28501 caacttgatt aaccttggtc tttacgacga tgttaaaaaa gaacttgcag ctgcaggtaa
    28561 agacttgatc gaagttgaag aagttgaatt ggaaccatct cttggtaatg gtggtttggg
    28621 acgtttggct gcctgcttta tcgactcaat tgctactctt ggtttgaatg gtgacggtgt
    28681 tggtcttaac taccactttg gtcttttcca acaagttctt aaaaacaacc aacaagaaac
    28741 aattccaaat gcatggttga cagagcaaaa ctggttggtt cgctcaagcc gtagctacca
    28801 agtaccattt gcagacttta ctttgacatc aactctttac gatattgatg ttactggtta
    28861 tgaaacagcg actaaaaacc gcttgcgttt gtttgacttg gattcagttg attcttctat
    28921 tattaaagat ggtatcaact ttgacaagac agatatcgct cgcaacttaa ctctcttcct
    28981 ttacccagat gatagtgacc gtcaaggtga attgctccgt atcttccaac aatacttcat
    29041 ggtttcaaac ggtgcgcaat tgatcatcga cgaagcaatc gaaaaaggaa gcaacttgca
    29101 tgaccttgct gactacgcag ttgtccaaat caacgatact cacccatcaa tggtgattcc
    29161 tgaattgatt cgtcttttga ctgcacgtgg tatcgagctt gacgaagcaa tctcaattgt
    29221 tcgtagcatg actgcctaca ctaaccacac aatccttgct gaggcgcttg aaaaatggcc
    29281 tcttgaattc ttgcaagaag tggttcctca cttggtacca atcatcgaag aattggaccg
    29341 tcgtgtgaag gcagagtaca aagatccagc tgttcaaatc atcgatgaga gcggacgtgt
    29401 tcacatggct cacatggata tccactacgg atacagtgtt aacggggttg cagcacttca
    29461 tactgaaatc ttgaaaaatt ctgagttgaa agccttctac gacctttacc cagaaaagtt
    29521 caacaacaaa acaaacggta tcactttccg tcgttggctt atgcatgcta acccaagatt
    29581 gtctcactac ttggatgaga ttcttggaga tggttggcac catgaagcag atgagcttga
    29641 aaaacttttg tcttatgaag acaaagcagc tgtcaaagaa aaattggaaa gcatcaaggc
    29701 tcacaacaaa cgtaaattgg ctcgtcactt gaaagaacac caaggtgtgg aaatcaatcc
    29761 aaattctatc tttgatatcc aaatcaaacg tcttcacgag tacaaacgcc aacaaatgaa
    29821 cgctttgtac gtgatccaca aataccttga catcaaagct ggtaacatcc ctgctcgtcc
    29881 aatcacaatc ttctttggtg gtaaagcagc tccagcctac acaatcgctc aagacattat
    29941 ccatttaatc ctttgcatgt cagaagttat tgctaacgat ccagcagtag ctccacactt
    30001 gcaagtagtt atggttgaaa actacaacgt tactgcagca agtttcctta tcccagcatg
    30061 tgatatctca gaacaaatct cacttgcttc taaagaagct tcaggtactg gtaacatgaa
    30121 attcatgttg aacggagctt tgacacttgg tactatggac ggtgctaacg tggaaatcgc
    30181 tgagttggtt ggagaagaaa acatctacat cttcggtgaa gattcagaaa ctgttatcga
    30241 cctttacgca aaagcagctt acaaatcaag cgaattctac gctcgtgaag ctatcaaacc
    30301 attggttgac ttcatcgtta gtgatgcagt tcttgcagct ggaaacaaag agcgcttgga
    30361 acgtctttac aatgaattga tcaacaaaga ctggttcatg actcttcttg acttggaaga
    30421 ctacatcaaa gtcaaagagc aaatgcttgc tgactacgaa gaccgtgacg catggttgga
    30481 taaagtcatc gttaacattt ctaaagcagg attcttctca tctgaccgta caatcgctca
    30541 gtataacgaa gacatctggc acttgaacta atactcttcg aaaatctctt caaaccacgt
    30601 cagctttatc tgcaacctca aagcggtgct ttgagcaacc tgcggctagc ttcctagttt
    30661 actctttggt tttcattgag tataagatac aaatttatac taatacattt tgtaaaaaag
    30721 cgagtttcga ttgaaattcg cttttttaaa tgctgtagat ttgggtcaat cttgtctaaa
    30781 aatagggaaa tcctagatac agtgaagact ttaaatgctg gtttttactg tcctcagcct
    30841 tatatttttt cgtagttgat tacctcacac ctcttgtatt cgcttacata aagtattata
    30901 atataattgt aggaaagaag gtgtttttat gatatacaca cttaaattgg tgttgtttat
    30961 tacctttctt gtaataagct tgttacctga taagattttt ggaaaaaata aaaaaatttg
    31021 gaaaatagtt tttgcaatat tgacggcagt ggcagcattg tcatttatgt actaagttat
    31081 tttaagaatg tagggaaata aaccctacat tctttttagt tttttctgtt ttctaaattc
    31141 tatttatcca agcgcttcaa catttcttgc ttcttcgctt caagttctgc acgcttttct
    31201 tcgatttcgg catgtttttt ctcgagttca gaacaacttg caccattgct aaattctttt
    31261 cgccatcagg agatagggtg agtcgacatg tctattactc acccaaagca gtcctacaaa
    31321 gcaggaattt tctgttactt ttttggaaat agtaacgttt atacagcttt gacacttcgt
    31381 atcaaagcgc caaacacact ccgagggatt tacagaaagc agaaaaggaa tgatctggta
    31441 taagatcatt ccttttctct ctttttcttt aagtaattat atacaatgta cgacgaagtc
    31501 gtcattgcaa tgctgatcca ccacctaaag ggaactttaa acaacattga taagataaag
    31561 aatataaaca acgaaaatac gttataccca attaatttta ttgtatatct catgattaaa
    31621 agttaatcct tccgttgtta ggaatggcat catttttatc ccataattgt gctaaataag
    31681 tccccggtga taataaattc atagcggatt ctaaagcaac atcatttaca aaccaactac
    31741 ctagatatct agaaattgct gaacgaatag cactttttgc tgcatgtttt ccttttactt
    31801 taattagatt tgcaaggcct gcagtagttc ctcctaatgc taaagctatt gtagtatcta
    31861 atagagcacc catttgatta actgtaatac cttgccaagc tgctctaaat ggagagtatg
    31921 taggtgggat tgtataatcg ccttgtaatt gtcggttaat tacttctttg atccattgtt
    31981 gtgagacgtc tggatgaaaa gattggattt cgtttgcaag tgtattgatt tgttcttctg
    32041 ttagagaagt gacaggttga agttccatat ttgtttcaat ttgcgatact tgttcagaag
    32101 cgtatacagc tgaaacactt ggaatcgctg atacaattaa cacaattgac gtcaaaaaaa
    32161 ccgaaataaa tttcattaat ttgttcatga gcttttctcc tttttatttg tatctgctta
    32221 cattttatta tatactgtta ttatagtcaa gaaaaatatg ctattatgtt aaaaaaatat
    32281 ttttcaaaat ataaatggac ggatttattt tggattttat ttgttatttt gacctgcctc
    32341 tatattggta accatgattt gtttactctc aatcatcaag aattctcttt tcgtggtagc
    32401 ttttggggtt tggtactggc cttatatcac ttattgttca ttgataagtt tgtaatttcg
    32461 aatcgaaaat aaagattaga actatgattg actggctact tttaatattg attttggagg
    32521 aagattttgt ctctattatt tattatttta aatttatcta ttttgtacaa tatctattct
    32581 ttgagacggg agaaatcgaa atacttgatt tatacggcct atatcatatt tggggtaaat
    32641 gtagtatatg gtattcaatg gttattaaga gaactgattt caactatttc cccttaatgt
    32701 gtatggaaac tataacaaaa cgcataagat taaggtttgt gtacctgttc ttatgcgttt
    32761 ttgtaatatt gaagattttc ggtaagtttt atacctttgg gaagtctagt ttagaatgct
    32821 ttcccaacca gaatctctgc ttcgatggta atctctgtca gttggctcca gtcaatcttg
    32881 ctctggtcaa catgaaagag gagaggagtc atactgagta gggcttggag ttgttctgct
    32941 gtgatagtct tagtcagaga ggcagtttga ctagatagga tggtaaagtg ttcctggaaa
    33001 tgctccttga tatcttggtt agaatactcc ttgtttgtca gctggtcctg tactctttga
    33061 cggatttctt tgaggtgatt ttcagttggg ataaccttta tcaagatacc gtctttggat
    33121 aaaacgcgac gaaattctcc atagttggca ggtgagaaga tatcaagcag aatatccatg
    33181 ttagcgtctt ttataggaag tcgtgccaag tcgccaacga accaattgac tgcccagttg
    33241 ggttcacttt tagcagcgat ttggactgaa tctttggaga tgtcaaaggc atagaaagtt
    33301 ttttcagagt gactttcttg tagtttgcga gaatagaatc cttcaccaca accgatatcc
    33361 aaaattgttg tggtagtttt tgagcttgca agcaagtcag atacagcatc taagatagct
    33421 tggtaaaagc cggcttctag gatttgttga cggttttgaa aattttcctt gtcatagtta
    33481 gcagattgct tgatttgagg tgctagattg acatagccaa atttcgccaa gtcaaaagaa
    33541 tgacggttgc agcacttgaa attagtctct aacagagtca gattttcttg acagatagga
    33601 caggcaaagg cagtcgcaga agcaaaacgc tgaagtttgg gcttgagatt tgtattcata
    33661 gtttaagtgt atcaaaagag gcaaatgaaa gcaactttag gaataagtag atgggagatt
    33721 cagtagaaat aaaactaatt ctccaattta tagaatgaaa ttgcttttat atctaaattg
    33781 ctatataata atgataagga ggaaataagt atgttaaaag aagtattaac cgttgcaaaa
    33841 gttgcgaaaa aatcttcatt atttttgggt ggtgtcgcat ttggtaccct tggtttgaaa
    33901 atcttagcaa gtaaggaagc taaaaaaggt tattctaaag ctttggctaa ggcttacaag
    33961 ttgaaagacg agctagatgc atctgtttct gttgtgaagc aacatggaga cgatgtcttg
    34021 caagatgcca aatatttgta cgagcaagag aaaaaagaag agcaattaga tagccttata
    34081 ggtgaataat atgtctttta aagtgctaca tagaggatac caacatatcc gactatcatc
    34141 ttctttttca cttaccttgg atattcaaga ctatcttcgt tccttggcga gagatgaaaa
    34201 ggggattgag tctatccagt tttacatgga tcaacagcac tttactctac gcataaaaga
    34261 aggcttttct gtattagata atgcagaagc ctttttaaaa agaattgata aagggaaagt
    34321 ttctgagttg atgactcttc ccattcgtag agaagagagt gcttattcta ttgtttcagg
    34381 tgcagcggtt aagcgtgtac tttttcgtag ttttgtgccg tatcctattc gctatatatg
    34441 gacttgttat caggctttgg gttatattag agaagcctat caaacactag cgcgtaagga
    34501 actaacgatg gaagtcttgg actgttcggc tattttattg tctttgttta tgaaccaatc
    34561 caagacagct agcaatatca tgtttatgct tgatttgggg aatcatttag atcagtggtc
    34621 cttgaaaaaa actgcaacag atttagaaca gagtcttctt gcaaaagaga gcgatgtatt
    34681 cctagtacag ggcgatacgg ttgttagtat caagagttcc gatgttcaaa taggagatgt
    34741 cttgatctta tctcaaggaa atgaaattct gtttgatgga caagtagttt caggtttagg
    34801 tatggtcaac gaaagttcct tgacaggaga gagttttcca gttgaaaaaa gagagtctga
    34861 tttggtttgt gcaaatacag tattagaaac tggagagtta cgcattcgtg taacagataa
    34921 tcagatgaac agccgtattt tacagctgat taagttgatg aagaaatctg aagaaaacaa
    34981 gaaaacgaaa caacgctatt tcatcaagat ggcggataaa gtcgttaaat ataatttctt
    35041 gggggctggg ctgacttacc tattgacagg ttctttttct aaggctattt ctttcctatt
    35101 ggtcgatttc tcctgcgctt tgaaaatctc tactcctgta gcttatttga cagttatcaa
    35161 ggaagggttg aaccgtgaaa tggtgattaa ggatggagat gttctggaga aatatctgga
    35221 agttgatact ttcttgtttg ataagacagg aacaatcaca actagttatc ctatagttga
    35281 aaaggtgtta ccttttggag actatagtga ggaagatatt ctcagaatca gtgcctgtct
    35341 tgaggaacac atttatcatc ctattgctaa tgccatcgtc aagcaagctg agatagaggg
    35401 aattgaacat gaggaaatgc atgggaaact ccaatatatc gcaagcaagg ggatcaaatc
    35461 tcatatagat ggccaaccag ttcttattgg gaattatgtc ttgatgcagg atgagcagat
    35521 tcatatcagt tcagaacaaa atgctttaat tgaagagtac aagagtcact acaatctctt
    35581 attcttggct tatcaaaatg aattgattgg aatgttctgc attcatactc ctttgagaaa
    35641 agaagcaaaa acagccttgg ataaacttaa ggcacagggg aaaaaattga ttctggcaac
    35701 aggagacacc ttgattagga cagaggaatt agtcaaagat ttgccctttg atcaggtcta
    35761 tacagacttg aaacctgatg ggaaatttga gttagtagag aaactgcaga aagcaggtca
    35821 cactattttg atggttggag atggattgaa tgactcagcg gctttaactc tatcagatat
    35881 cggtgtggtg atgaatgaga gtgcagatat ttctaagcag atgagtgata tcttattgtt
    35941 agataatcgt ttggatttct tccaagagtt ggattcgtta tcatcatctt tgcaaacact
    36001 catcaagaaa aatattcaag ataccgttgt cgtaaatagt agtttgattg gctttggctt
    36061 atttaattgg ctcagtcctt caaatctctc tatcttacat aatctaacaa ccttgcgcat
    36121 tgtcctgcgt agcctgtcta ttaaaaatag atagatgaga gttattaaca gcaaaaagga
    36181 gttacctttc tcgaggttaa ctcctttgtt tatagataaa tgttgaatgg tttagtaagt
    36241 caatacaaag tattttttct tcccacgacg gataacagtc agttcatttt ctaacttatc
    36301 agcgtcactc aagacatagt caaggtcttg gatgcggtcg ccgtttacgt agatggctcc
    36361 gttttggacg tcttcacggg cttggcgttt tgagttaact ataccagatg agacgagcag
    36421 ttccacgata ttgttgtttt cgtctgcctg tacttggtag tttggcacac cacgaagtcc
    36481 ttgtttgagc tctttgacag aaaggttttt gatgtttcct gcaaagagtt gctcagtgat
    36541 gttaagtgct tctttgtagg cttcttctcc gtgaacaagt gtaacaactt cacgagccaa
    36601 gactttttga gccaagcgtt cgtgtggcgc tgcttcaaat tgtttacgaa tatcttcaat
    36661 ctcatcaagt gacaagaaag taaagatttt caagaagcga acagcgtcag cgtccatcac
    36721 gttcatccag aattggtaca tttcgtatgg agaagtcttt tcgggattga gccagacggc
    36781 atttccttct gatttaccaa attttttacc agttgcatct gtgattagtg gaacagtgat
    36841 aacgtgacca gtcttgtccg ccttacgacg aagcaattcg gtaccagctg tcatatttcc
    36901 ccactggtca gaaccaccga tttgaagagt gacattatgg tcttggttaa ggacgaagaa
    36961 gtcgtaccct tgcatgattt ggtaagcgaa ctcagtgtaa gaaattcctg tttcgatccg
    37021 ttttttaaca gattccttac tcatcatgta gttgaccgtg aagtattttc caatgtcacg
    37081 gaggaagtca atgaagctga tgctgccaaa ccagtcgtag ttgttgacca tgacagcctt
    37141 gttttcgcca ttttcaaagt caagaaaacg agaaagttgt ccttggatag acttgaccca
    37201 gccatctact gtgtcttttg tttggagact acgttcagca tctttgaagg acggatctcc
    37261 gatgagacct gtagcaccgc caacgagcgc ataaggtttg tgacctgcta gttgcaagcg
    37321 acgacttgtc aagattgcga caaggtggcc taggtgaagg ctgtcagcag ttggatcgta
    37381 gccagtataa taagaaactt gaccttcttc tagggcttta cgcaaagctt cttcatcagt
    37441 cgtttgaaat atcaaaccac gctcttttag ctcatcaaaa atgtgcatgt gtcttttctc
    37501 ctttttaaaa ttattgtttc tacctattgt atcacaaact tgggcaatag cctagcagaa
    37561 tagggaagaa agtggctatt ttattgaaaa tttccctttt gtggtataat agatagagtg
    37621 aggaaatcca tgcaaaatca attaaatgaa ttaaaacgaa aaatgctgga atttttccag
    37681 caaaaacaaa aaaataaaaa atcagctaga cctggcaaga aaggttcaag taccaaaaaa
    37741 tctaaaacct tagataagtc agccattttc ccagctattt tactgagtat aaaagcctta
    37801 tttaacttac tctttgtact cggttttcta ggaggaatgt tgggagttgg gattgctttg
    37861 gggtacggag tggccttatt tgacaaggtt cgggtgcctc agacagaaga attggtgaat
    37921 caggtcaagg acatctcttc tatttcagag attacctatt cggacgggac ggtgattgct
    37981 tccatagaga gtgatttgtt gcgcacttct atctcatctg agcaaatttc ggaaaatctg
    38041 aagaaggcta tcattgcgac agaagatgaa cactttaaag aacataaggg tgtagtaccc
    38101 aaggcggtga ttcgtgcgac cttggggaaa tttgtaggtt tgggttcctc tagtgggggt
    38161 tcaaccttga cccagcaact aattaaacag caggttgttg gggatgcgcc gaccttggct
    38221 cgtaaggcgg cagagattgt ggatgctctt gccttggaac gcgccatgaa taaagatgag
    38281 attttaacga cctatctcaa tgtggctccc tttggccgaa ataataaggg acagaatatt
    38341 gcaggggctc ggcaagcagc tgagggaatt ttcggtgtag atgccagtca gttgactgtt
    38401 cctcaagcag catttttagc aggactccca cagagtccca ttacttactc tccttatgaa
    38461 aatactgggg agttgaagag tgatgaagac ctagaaattg gcttaagacg ggctaaggca
    38521 gttctttaca gtatgtatcg tacaggtgca ttaagcaaag acgagtattc tcagtacaag
    38581 gattatgacc ttaaacagga ctttttacca tcgggcacgg ttacaggaat ttcacgagac
    38641 tatttatact ttacaacttt ggcagaagct caagaacgta tgtatgacta tctagctcag
    38701 agagacaatg tctccgctaa ggagttgaaa aatgaggcaa ctcagaagtt ttatcgagat
    38761 ttggcagcca aggaaattga aaatggtggt tataagatta ctactaccat agatcagaaa
    38821 attcattctg ccatgcaaag tgcggttgct gattatggct atcttttaga cgatggaaca
    38881 ggtcgtgtag aagtagggaa tgtcttgatg gacaaccaaa caggtgctat tctaggcttt
    38941 gtaggtggtc gtaattatca agaaaatcaa aataatcatg cctttgatac caaacgttcg
    39001 ccagcttcta ctaccaagcc cttgctggcc tacggtattg ctattgacca gggcttgatg
    39061 ggaagtgaaa cgattctatc taactatcca acaaactttg ctaatggcaa tccgattatg
    39121 tatgctaata gcaagggaac aggaatgatg accttgggag aagctctgaa ctattcatgg
    39181 aatatccctg cttactggac ctatcgtatg ctccgtgaaa agggtgttga tgtcaagggt
    39241 tatatggaaa agatgggtta cgagattcct gagtacggta ttgagagctt gccaatgggt
    39301 ggtggtattg aagtcacagt tgcccagcat accaatggct atcagacctt agctaataat
    39361 ggagtttatc atcagaagca tgtgatttca aagattgaag cagcagatgg tagagtggtg
    39421 tatgagtatc aggataaacc ggttcaagtc tattcaaaag ctactgcgac gattatgcag
    39481 ggattgctac gagaagttct atcctctcgt gtgacaacaa ccttcaagtc taacctgact
    39541 tctttaaatc ctactctggc taatgcagat tggattggga agactggtac aaccaaccaa
    39601 gacgaaaata tgtggctcat gctttcgaca cctagattaa ccctaggtgg ctggattggg
    39661 catgatgata atcattcatt gtcacgtaga gcaggttatt ctaataactc taattacatg
    39721 gctcatctgg taaatgcgat tcagcaagct tccccaagca tttgggggaa cgagcgcttt
    39781 gctttagatc ctagtgtagt gaaatcggaa gtcttgaaat caacaggtca aaaaccaggg
    39841 aaggtttctg ttgaaggaaa agaagtagag gtcacaggtt cgactgttac cagctattgg
    39901 gctaataagt caggagcgcc agcgacaagt tatcgctttg ctattggcgg aagtgatgcg
    39961 gattatcaga atgcttggtc tagtattgtg gggagtctac caactccatc cagctccagc
    40021 agttcaagta gtagttctag cgatagcagt aactcaagta ctacacgacc ttcttcttca
    40081 agggcgagac gataattctc taaatgaagt ggccaatcaa tggattgcca cttttttcct
    40141 ttcgtgttac aataagggta tgaatcagta tcagaaaaag attgttaacg gaaaaattta
    40201 ttcgctccta tccggcttaa tatggggaat ctgtggaatt ttaggagagt acttctttac
    40261 tcattatcag gtgtcttcgg gctggattac ctctatgcgt ttgacactgg cagggagtct
    40321 tgtactcatt tggtctgcaa tacaattaaa atcgcaagtg ctagatattt ggcgagacaa
    40381 gaaaaattac ctgccctttt tagcctatgc tattttgggg attttttcag ttcagtattt
    40441 tttctatctc tgtgtagaat actcaaatgc tacgacagca actattttac agtttattag
    40501 ccctgttttt atcctctttt acaatcgctt ggtttatcaa aaacgagcgt caaaaagcgc
    40561 tgttttctat gttttggttg ccatgctggg tgtttgcttg atggcgacaa agggagatct
    40621 ctctcagtta tccatgacgc cgctagctct tataacaggt ttgctgagtg ccatgggtgt
    40681 tatgtttaat gttatcttgc cccaaccttt tgctaagcgt tatggttttg ttcctacggt
    40741 tgggtggggg atgattttgg caggtttgtt tagcaatgtc ctctcgccgg tttatcagct
    40801 ttcctttact cttgatattt ggagtatctt gatttgcctc attatcgctt tctttggaac
    40861 ggcttttgct tttttcattt ccatgaaggc tgtgtccttg gtttctcctt tggtggttgc
    40921 cgttatcagt gccagtgaac ctctctcttc tgctctcttg agtgttttgt tcttaggatt
    40981 agtagtggat tggtccctcc ttctagctat agccttgatt attttaccca tgatattttt
    41041 gtctatagaa gaagcgaaag aaagtagata aaaagtcttt tcttaattct aaaagtgtgc
    41101 tatactagaa tagtcaataa aacacgggga gatagttgtg aagagtgttt ttaggttgta
    41161 tcggtagggg cttgctttta ccgacagcac gttttatctc acatccctaa aaaatcatac
    41221 ctaaaaacag acaaaaaggt ttcaaatttg aggccttttt tggtagaata ggtatcatta
    41281 taacgaacca ggaggcacct atgactgcta caaaaatgaa cgctcaagaa attatccaat
    41341 ttatcgccaa tgctgaaaag aaaaccagtg tcaaagtaac ctttgagggg caactcgcaa
    41401 ctgctgtgcc tagctctgtt gtcaaactag gaaatgtcct attcggagac tggaaggacg
    41461 tggctccgct tcttgaaggt ttggtagaaa atcaagatta tgttgtcgag caagatgctc
    41521 gtaattctgc agttcctttg ctagataagc gtgctatcaa cgctcgtatc gagccaggtg
    41581 ctattatccg tgaccaggtg gaaattggtg acaatgctgt tatcatgatg ggagctgtta
    41641 tcaatatcgg tgctgaaatc ggtgctggaa ccatgattga catgggtgcc atccttggtg
    41701 gccgtgctat cgttggaaaa aatagccacg ttggtgcagg tgcagttttg gcaggtgtga
    41761 ttgagccagc tagtgctgaa ccagtccgtg tcggagacaa tgttcttatc ggtgctaatg
    41821 cagtggttat cgaaggagtc caaatcggta gtggttcagt tgtcgctgca ggagctatcg
    41881 ttacccaaga tgtcccagaa aacgtggtag tagcaggtgt tccagctcgt atcatcaaag
    41941 aaattgatgc ccaaacccaa caaaaaacag cgctagagga tgcgcttcgt accttgtaat
    42001 tgtaaaagta aaaaagaggc ggaacccttt ttccagcctc tttctgctat aacggaggac
    42061 agatagatgt tagatttgat tcagactaga cgagctttac accagattcc agagattggc
    42121 ttggaggagt tcaagactca ggcttatttg ctggatgtga ttgagaaatt gactacgggc
    42181 aaggattttg ttcaaattcg tacttggcgg acagggattt tggtctacct gcagggaagt
    42241 cagccggagc gaaccattgg ttggcggaca gatattgatg gtctgcctat cgtcgaacaa
    42301 acaggtctac cttttgcttc tcaacaccaa ggtcgcatgc atgcctgtgg ccatgatttt
    42361 catatgacca ttgccttagg ctgtcttgag cgcgcccttg aggagcaacc caagaataat
    42421 ctgctctttc tatttcagcc tgctgaagaa aatgaagctg gtggcatgct catgtatgag
    42481 gacggtgctt ttggagattg gttgccaaac caattctatg gtctccatgt tcgtccagat
    42541 ttgaaagtcg gccagattgc gactaatact catacactct ttgcaggaac ttgcgaggtg
    42601 aagatccgtt tcaaaggcaa aggtggccac gcagcttttc ctcatgaagc caatgacgcc
    42661 ttggtggcgg ctagttactt tgtgacccaa gtgcagtcag ttgttagccg caatgtcaac
    42721 ccaatcgagg gagcagtggt gaccttcggc gtttttcaag ctggaaccac caacaatgtc
    42781 atcacagaca cagctttttt acatggaact attcgtgcct tgacacagga catgagtctc
    42841 ttggtgcaaa agagggtaaa aacagttgca gaaggggttg cagctgcctt tgatatggaa
    42901 gtcgaagtgg aactcaaaca aggtggatac ctacctgttg agaacaatcc agccttggcg
    42961 cgtgaactga tggacttctt tgacgaaaaa gacggaatcg agttgattga tatcgaacct
    43021 gctatgacag gcgaggactt tggttatctc ctttcaaagg ttgatggcgt gatgttttgg
    43081 ctaggtatcg atagtcccta cgctcttcat caccctcaaa tgagtcctaa ggaagaagtc
    43141 ttagctattg gggtggctgc ggtgtctagt ttcctgaaaa agaaggcagc agaatagagg
    43201 gcttgtctat gaaatcggaa ttacgcaagc aagtcttgca tgaaatgaag gctatatctc
    43261 aagagcaaaa acaggctata gaccaagctt taaccgagcg gcttttacac catcccttct
    43321 accaagaagc caaggtcatc gcaacctacc tctctttttc tcatgagttt caaacgcggg
    43381 aactgattga gcaggcgctg aaggacggca agaaggtttt aatacccaaa acttatccca
    43441 aggggcgcat ggagtttgtg gtctatgatc cgcaacagtt ggtaaaaact tcctttgcct
    43501 tactggagcc acagggagat gtggaagtgg tggatgcatc tcagattgat ttgattcatg
    43561 ttcctggtct ggcttttacg acgaaaggat atcggatagg atacggtgga ggctattatg
    43621 accgctatct ggaacatttt tctggtcgta ctttgagtac gatatatcct tgtcaaattc
    43681 aggactttat acctgaaaac catgatattc ctgttcagga ggtattaatt gatgaaggaa
    43741 atctttgata gacgttaccc tgtgacgagt ttcttcctct tagtgacggc cttggtattt
    43801 ttactaatgt tggtcactgc aggcggaaac tttgacaggg cagatacatt atttcgattt
    43861 ggagccatgt atgggccagc tattcgcctc tttcccgagc aggtttggcg tctcttgtct
    43921 gccatttttg ttcatattgg gtgggaacat ttcattgtta atatgctttc actttattat
    43981 cttggaaggc aggtagagga gattttcggt tctaagcagt ttttctttct ctatctttta
    44041 tcaggaatga tgggcaatct ctttgttttt gtatttagtc ctaaatcctt agcagcaggc
    44101 gcttctacct ctctttatgg gctatttgcc gcgattattg ttcttcgcta tgcaactcgc
    44161 aatccttata ttcaacagct agggcaatcc tatctgacac tttttgtggt taacattatt
    44221 ggaagtgttc tgattccagg aatcagccta gcaggccata tcggtggtgc agttggtggc
    44281 gcatttctag cagttatctt tccagttaga ggagaaaaac ggatgtataa taccagccag
    44341 agattaggag cggtagtctt gttcgtagga ctcgccattt tgcttttcta caagggaatg
    44401 ggaatgtgac gaagttgaaa gaaaatttgt gtaatgaaaa aagataaggc attttttgaa
    44461 ccttatcttt ttattttatt ttattccttc tcagtcaatt cttttccaag ttggatgagg
    44521 taattcttca aatcatcttt gacttgtggg tgtttgaggg cgtagtcgat ggatgttttc
    44581 atgaagccaa acttgtctcc gacatcgtaa cgagccccat tgaactcacg agcaaataca
    44641 cgttgtgttt tattgagggt gtcgattgca tctgtcagct gaatttcatt tcctgcacct
    44701 ggagcttggt tttcgaggat ttggaaaatt tcaggcgtga ggaggtagcg tccgataata
    44761 gcaaggtcgc taggagcgtc ctctggagct ggtttttcaa caaaggtttc aacactgtaa
    44821 agaccatctt ttccttcgcc ttgcggagca ataaccccgt aagcagatac ttcgtcatga
    44881 gggactggca tgacagcgat agtagacgcg tgggtacgct cgtagtcatc catgagttgt
    44941 ttggtaagtg gaacagcctt ttcgtctgtg atatccatca agtcatcacc aagcataacg
    45001 acaaaaggtt catttccgac gaaagcctta gcttgcaaaa cagcatctcc gagaccgcgt
    45061 ggatgagttt ggcggataaa atgcagacgc atgtcagttg ttttatcaac tagcttcaaa
    45121 agatctgttt tccctttttc tttgaggtta tattccaatt cgaagtttga atcaaagtgg
    45181 tcctcaatag aacgttttga tttaccagtg acaactagaa tatcttcaat acctgatttg
    45241 agagcttctt ccacgataaa ctggatagtt ggtttgtcta cgattggcaa catttctttg
    45301 gcaagggcct tggttgctgg taaaaatcga gttcctagtc cagcagcagg gatgactgcc
    45361 tttctaactt ttgatgtcat aaaaatcctt tctatagagg gttaagacca ctcattttct
    45421 gctttaaatt cattgttcat gatgtcataa atggcatctt tgatattggt tccgtgataa
    45481 ataacttggt aaatagcctg tgtaatgggc atatagactc caagttcttg ggctagttca
    45541 taggctgctc gagtcgttga aattccttcg attaccatgc ccatattagc ttctatatca
    45601 gctagggatt ctcctcgtcc gagagcatct ccagctctcc agttacgaga gtggatggaa
    45661 gttcccgtta cgatcaaatc tcccacacca gataagccgc tataggtcaa tggactggcc
    45721 ccgagtgcta cccctaggcg ggtgatttct gctaaacctc gagcgatgat ggctgcctta
    45781 gcattatcac caaatccaag accatgtaaa gctccagcac cgacagcaat aatattttta
    45841 agagcaccag cagtttcaac cccgataaca tccgtattgg tataaagtcg gaagtagtga
    45901 ttactaaata gcttctgaac gtattgagct gtttgtaaat ctttagaagc agcagttatt
    45961 aaagttaggt cacgcacaat ggtctcttct gcatgactag gccctgaaac aacgacgata
    46021 tcactacgga gatgttcagg aatttcttct tcaagaatgg ttgataatcg tttatggcta
    46081 tcaggttcta atccctttga tgcgtgcatg atgataacct tatggtccaa ggtttgtgca
    46141 acttgctggg caacaagtcg tgtcactttt gttgggacaa caaacaaaat cgcatccaca
    46201 tctttcaatg tttctgctaa gtcggtgtag gcaatgatat tttcgtctag aacgacatct
    46261 ttaaagtagt gcttattagt atggtgtgta ttaatttcat tgatttgctc gggaagattt
    46321 ccccaaatac gtacctcgtg tccattgtca tttaagactt gtgaaagggc ggttccccaa
    46381 gaaccaggcc ccaagacggc gacggtttgt ttttccatga tttcctcctt gatagagttc
    46441 tttctcttat tctatcatat tctaggggat tttgcacttg cattactggg gtatggtgga
    46501 aaaatacaca aaaaccgaga cgaagggata aactcttagt ctttagttaa agtgagaaga
    46561 aatctgatag atagtttgat tcagtatatg cttataatag aggtaaacaa ctcaggaagt
    46621 tcttgtaggt tgcgagagtt tggctaaaaa aatcagtcgt tcagaatttt gtggtgatga
    46681 gtctgaatta agtatccgtc aattaattag aattgaaaat ggagaatcca gaccaacact
    46741 aacaaagtta aaatatatcg ctgaacgttt gggggttgaa gattacaagt tgatgccaag
    46801 ttatatagag ttggataagg aatacctaga attgaagtat ttcttgatga ggactcctac
    46861 atacgaagat gaaactatcg cccaaaagaa agagagtgtt ttgataagat ttttgaagag
    46921 tattatgata ggctacctga ggaagaaaga tttatcatcc caaattattc atatctggca
    46981 ctaacgaact acacagttca aaaattacca gaaaagctag ttgaaatact gtccttctgg
    47041 tgattttgct taatttctga tgttcgagac ataattgagg agatttgtct tgattttttc
    47101 ctaaaaaagg gcagactcct cccttggttt gatgctcgat ttttaaaata aggtgactta
    47161 ttctgttagg catgttttcc cctgccctct agctctatat ggaacaggga gtatcagatt
    47221 tatctggcag attgtatcaa ataaggcttg aaactgtttt gaataggcat atagacttga
    47281 gaatttgaga atatgtcgtc tagcagtaga gacatatttt ccggcaatat gaaggaagag
    47341 acgtcgaaaa cgcttgatag tcaaggcctt tacttcatca ccagctagct gctttaaaaa
    47401 gaggtagaga ttataagcca gacagcccat catcatacgt acttcattct taatcatggt
    47461 cgaactatct gtcttatccc caaagaatcc tgctttcctt tctttgataa agttttcagc
    47521 attccctcgt tcacgataga attgaaacag ctcctcacta tctacactgc ttaaattgtt
    47581 caaatgaact tttttacaac cataaaaaag agcacttaat cgtactcttc tcttttaagg
    47641 attagttgaa ttaattcaaa tccaccagtt ctcctgtttc taggtagact aggcgttcac
    47701 aaatgttagc aatgtaatca gcgaagcgtt ccagatgccc tatgatataa aggtattgag
    47761 ttccattggg aattgaggtt tcttggtctt tcataagtcc aatgatttcc tttgataagg
    47821 cataataata ttggtcaatc tgttcatctt tttgagcaat actaatagct tttgaggctt
    47881 ggtgcaaagg aaaggcaacc aataaatcgg ctagcatgct gagggataat ttacccattt
    47941 ggtgtaactg ttcttcgtca ggggctagtt gattttcttt tagttgcaaa acagctttag
    48001 caatgcctgc catatggtct cccatacgtt caaggtctga acaagaagac atgatgctaa
    48061 tcacaaatcg aaggtcagac acttgtggct gctgcaaggc caacaaacgg gcacaggtca
    48121 attcgatagc gctttgacct tggttgatag catgatcctt attgataatt agctctgcca
    48181 tctccttgtc tttggaggct aaggccagta aggcttttga agctgtttca aggacaagtt
    48241 gccctagtcc taaaaaggat tgttctaatt catgcaattc taagtcaaat tgatttctca
    48301 taggtttttc cttccttatc cgaaccgtcc tgaaatatag tcttctgtgc gctgatcttt
    48361 tggattggta aacacgtcaa cggtatctcc aaattcgcaa atttctcctg ttaagaaaaa
    48421 agcagtttta tctgaaatac gtgaagcttg ttgcatgtta tgggtaacaa tgataatcgt
    48481 ataatccttt tttagttgct gaatgaggtc ttcaattttt aaagtggaga tagggtctaa
    48541 ggctgaagtc ggctcatcca ttaacagaat atcaggttct actgctaaag ctcgcgcaat
    48601 gcaaaggcgt tgctgctgac cgccagataa ggacatggca ctctttttaa gatcatcttt
    48661 gacttcttcc caaatggctg ccccttttaa agatttctcc actaaggcat ctaattgttt
    48721 tttgtctcga ataccatgtg tccttgggcc ataagccacg ttatcataga tagacatggc
    48781 aaagggatta ggctgttgaa aaaccatccc tacacgctta cgtagctgat taaggttgaa
    48841 tttgctacta taaatatctt gctcatctaa gaggacttgg ccttcaatat ggcaagaagg
    48901 aaccaaatcg ttcatccggt taagggtttt tagaaaagtt gatttgccac aaccagatgg
    48961 gcctatcaag gcagtaatct gtctttctgg taattgaatc gaaatatttt ttaaggcttg
    49021 aaaatccccg taaaataagt ctaggtgtct gactgaaaat gttcccatac taggaagctc
    49081 ctttcacaag ttttcgagat aataagcttg atagagtatt tatcattaaa acagtaataa
    49141 tcaaaatcac accggtagca taggcttcat tgacatgtag cccctcactt gacagcatat
    49201 acatatgcag ggctagagaa cgacctgaag acatgagact acttggcgta ttggtagagg
    49261 tacctaatgt atacatgagg gcagctgttt caccaacgat acggccaata gctagtatca
    49321 ctccagctaa aatacctggc atggcaactg gtagaacaat tctaaaaaca gtccgtaact
    49381 tacctgcccc aagtccataa cttgcttgac gcatgctatc actaacagat aaaagggctt
    49441 cttctgttga gcgaataatg actggcaaca ccatgataac tgaggttaag attcctgata
    49501 acagagagta ttgaaaacct aagaagacta caaagaagag catgccaaac agaccaaaaa
    49561 caatggaagg aatcccagac aaggtatctg aggccaatcg catgatttta acacaaaggg
    49621 aatctttttt tgtatattcc acaagataaa aaccagcaaa aatccctatg ggcaaggcta
    49681 aaagaagagc accaaagacc agaataacgg tggaaataat cgctggcata agggaaatgt
    49741 tctcagaagt ataagtccaa gaaaagaggg atagacttag atgaggtaag cctttgatga
    49801 ggataaaacc aatgattaaa aagagagagc caaaggttaa agctgaaaaa caataaacga
    49861 gaagttttag caggtattta ctcataagat gattttcctt tcaagtaggc aaagtaggca
    49921 ttaatcaaga gaataaggaa aaagagaact gctgaggttg caataagggc ttccctatgc
    49981 tgacctgatg cgtaagccat ctccagaaca atattggttg ttaaggttct ggttcctgaa
    50041 aagagtccac ttggaataat tggctggttg cctgccacca aaataactgc catggtttca
    50101 cctactgcgc gaccgattcc taaaataact gctgataaaa taccagatct cgcagctggc
    50161 aagatgacac taaaaatact ccgttcatga ctagctccta gagccaagct accagaataa
    50221 tacgttttgg gaactgttcg gatagcagat tctgacaaac tgataatggt tggcaaaatc
    50281 attattccta atagtaacga agcggttagg acactcatgc catttcctaa aaagcttcta
    50341 atccaaggca ccaataattg taggccgaaa aaaccataaa caatagatgg aatggctgcc
    50401 atcaagttga tagctgattt taagaagcca tagacgggct ttggacaata ataaaccata
    50461 aacaccgatg tcaagatgcc tgttggcacc ccaatcacaa tcgctcctaa ggtaattaat
    50521 aaggaaccaa cgatcattgg taaaatacca tagcttgccg gaatgttcgt tggcgaccaa
    50581 tcactgccta ataaaaaacg ggcaaagccg tagttagcta tgaaaggtaa gccattacta
    50641 aaaataaaga aacagattag caaaatagct acaacagcta ctgttgcact catgaaaaaa
    50701 attgccctaa aaactgcttc tttgaaggct tgttttgtca catcttgtcc tttctagtga
    50761 agaaagtaag ggagatacga cacctcccta cttgccttct ttatcttatt gtacgatgaa
    50821 acgtctgcat ctctttagag atttatggag caaacatttt atttaatctt gtcccaggtg
    50881 gttaatttgc cactaaaaac gtctgcaagt tcagccatac tgacttggct tgccttattg
    50941 tcattattga ccacaacagc aataccgtct aaagcaatag catcatgggt gagactctta
    51001 ccttcttcag gagttaattc cctagaaacc ataccaatat cagcggtttt ctccttaaca
    51061 gcggtaatac ctgctgaaga cccattagag gtaatatcaa tcgtaacttc tggattttct
    51121 tttttataag cttctgctaa tttttccatt aaagaagata ctgaagtgga acctacaaca
    51181 gacaacttgc ctgataagtg ttggcttgta tattctgtgg tttcggtttt agcttcaata
    51241 aatttattat ctgtgaccac ttgttgacct tgtttggagt ggataaagct gataaaatct
    51301 tgacctagct tggaaagatt agaagaccaa acaatgttga agggacgttg aagagggtat
    51361 ttaccatcta aaactgtgtc tcgactagcc ttgacaccat caatctctaa agctttgaca
    51421 gatttcgtta aagatcccaa ggagatgtag ccgatagcat tagcattccc ttgaactgct
    51481 gagagaacac cttctgtact attttgaatc acagctgttt tggcagtgtt gtcaattttt
    51541 ttatcaccgt cttttttgag aatccctgtg atttctgtga aggcaccccg tgttccagag
    51601 ccattttctc gtgaaatcac ctcaatcgtt cctgaagctg actgtttgga agcagctgac
    51661 tgattgccac aggcaacaag cccaaatcct gataagccaa tggctgcaag agtaagcatt
    51721 tttttgaatt tcataataat cacctttatc tctatgtatt tttcttgtgt aggcttacta
    51781 catttatagt ctaacaagtc tttgtaaagg tttatccctg attcatgtaa agattgtgta
    51841 aagaatcaaa aaaagccact tttgaaaaat ggctgctcct aaaaatagct ttaaaaatta
    51901 ttagtcctgt gcgaaagatt ggttaggaag aaaaatcgtg aagcaactgc ctctgccaag
    51961 ctgactcgtc accgtgactt ggccacctaa taattgactg agttctttga caatggcaag
    52021 gccaagacca gtgccaccag tttgtctgct tcgaccttta ttaactcggt aaaaacgttc
    52081 aaaaatacga tcctgctcta attgactaat accaatccct gtatctgata cagaaatctt
    52141 aatgccttcg ttcacctttt gggtcttgac ctcaattttt cccccttgtt cagtgtaacg
    52201 gatggcattg gataaaagat tgagtaagat ttgggaaagt aattgactat ctgatacgag
    52261 ggtgacatca tctggcacct gcacctttag ctgtaaatcc ttcttcttga gctgaggttg
    52321 caagctttga gtcaaatcct gtacaaattc tgccaaagaa agggtcgtcc attgtatagg
    52381 catttgttga gccttagata aggtaagaag atgctcaaca atatgctcaa gacgcaagct
    52441 ttctttgtaa ataatgtcta gaaagtcatc cttgagcgct tcttcttcag ctgacatccc
    52501 cttaatggtt tcagcaaagc ccttaatcga agtaactggt gtcctcaatt catgggaggc
    52561 atttgagaca aaggctaaat ttaacttttc ataagttcta atcgttgtta aatcatatag
    52621 caagacgagc acagcttcca cagattgggt ggggctaaaa acgggaactg ctgtcacttc
    52681 taaaatcaag tcaccctcat gaaacccact tacttcttgt tttaaccttg ttttttgatc
    52741 aaaggcttgg tgaactaaat ttcgaatatc catccgtttg aggtcatcaa gtgaacttat
    52801 gtcgccgtcc acatcgggaa aataatgagg cagagagcga ctggataata acatctgacc
    52861 ttgagcggaa actaaaaacg tccccatggt taggtgcgac agaagaacct ccattgtttc
    52921 ggctaggtcc ttgtattgct gatcctgttg ggagactttg gtttttaggg cagacacata
    52981 ctgagccaaa gactttaagt cttcttgccc tttttctaaa aagtattcac tactggtcaa
    53041 gagaggttgg tgcaaggtct caaaagcaac ttcccatttc caaaggcaaa agagccagta
    53101 gccaccttgt cccaaagaaa gggctagaag aaagagaccg atgcctttac tgatccaagt
    53161 taataccatc cctgcaatca gaatgaggct aacacttaga ttgactagcc aaaattgaag
    53221 gtagcgtttc atctataact ccttgaactt ataaccataa ccccgaatgg ttcgaataaa
    53281 ttgaggggct ttaggattgt cttcaatttt ttccctcaac ttaccaatat gaacgtccac
    53341 caaacgtgtt tcctgcccaa agtcataccc ccagatacgt tccaaaagac gctctctagt
    53401 cagtgtcatg ttgggatgtt tcataagata gagcaagagt tcaaattctt ttggggtcaa
    53461 actcagtaac ttattcgcct tgtagacttc atgacgctca gggtatactt tcaaggtccc
    53521 aaatagccaa gaatcgtcag cgatattatc tgaatcatct ccttcttgtt ctcctttagt
    53581 tcgcctgagg acagccttga cacgcgccag caattctcta gggctaaaag gtttggtcag
    53641 gtagtcatca gcccctaatt ccaaggccaa aaccttatca aattcatcac ttttcgcaga
    53701 aaccatcata attggagttt tgacgccttt ggctctcagc cgcttacaaa cttccatgcc
    53761 atctaattgt ggtaacatga tatcaagcaa gataaaatca aagggttctg tttctgccaa
    53821 agctaaggcc ttccgtccat ttgttaccaa ttgagtagaa aagccttcct tacttaaatg
    53881 gtagtcaagc aatttcagaa tgtgttcttc atcatccact aataagactt gttttgtcat
    53941 ctattatctc ctattggtaa cattataaca caattatcag aaatcctaac attgctaaat
    54001 cagattaaat ttgcttatca agactagtat ctggtcaaac gctcaatcat ctccttgtgc
    54061 tctggatagg tcgccagtag atctaccctt tcaaataatt caaaatcctc aaattcaaaa
    54121 ccaggagcaa caagacaaga aaccagagca tcatccttat caactgttga tccccaaata
    54181 gtgcccttag gaacacagta gtgaagttgt tgccctttgg atatgtccag gcctaaagtg
    54241 actgcttcgt agtgaccatc tgctgtaatc atgtgaacag taagtgggga ttctgcatga
    54301 aaataccaga tttcatctgc tgtcaatcgg tgaaaatgtg aaggattcgt ttcttcttaa
    54361 taagaaataa atactggtat aaagcgccct tcccttacca gcaaggttta tagtgtctga
    54421 agcttttttt gtttgtctaa aatagccacc ttcaacatgg ggagctaact ctagagttct
    54481 tatcaagtct tctttatccg tcggagccaa tgggttgaag taactcttgt tcaaagtggt
    54541 gttacgattt caagaactcc tctcagttct gaggacacgg taatgattga tgcgacggaa
    54601 gtacaaatca atcgccctaa aaaaagaatt agcgaatcat tctggtaaaa agaaatttca
    54661 cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt tggatatcgc
    54721 tgtgaactat agtcatgata tgaagttgtt caaaatgagt cgcagaaata tcggacaagc
    54781 tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca
    54841 aattccacgt aaatccagca aactcaagcc gctaacagtt gaagataaag cctgtaacca
    54901 tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa
    54961 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat
    55021 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ttatttggtt
    55081 aggtgaatta gtgaagcgtt taggcaagtg tctctggtta cgacgtcatg gcctctaaat
    55141 cgattatatt taggggtcat gactagtgaa gcagttagct agttcgcata taagcggcta
    55201 gcgtctaaca attaggaact ttagttccaa taactttaag attacgacgt tttaggacat
    55261 aaatcgatca tatttatgtc ctaaaactag tgaagcgcct agccaaagtc cgaataggat
    55321 ttggcgttag ttacttagat tgctttgcaa tcaagtaact ttggcgattt acatcttctc
    55381 tggtgcttct actccaagca agcgaagggc ttctttgaga acgactgcgg ttgcgtagct
    55441 gagggctaga cggctgtcgc gttctgggct ttcatccaag atacgtgtat gtgcatagta
    55501 tttgttaaag gattgagcca ggctaattgc aaatttagca atgatagaag gttcaaagtt
    55561 atctgccgca cggttgataa tacgtgggaa gtcttgaatg agtttaatga tttcccagct
    55621 ttcagtatca ttcaagctat agttgccagc tgtttctggt ttgaaatcgg ctttgcgtaa
    55681 gatagattgg atacgagcgt aggcatattg aacgtaaggt ccagtttcac cctcgaagga
    55741 taccatagct tctaggtcga agtcgtatcc atttgtacgg tcagttttga ggtcatagaa
    55801 tttaatggct ccaaccccaa cagcatgtgc tacttggtct ttgttttcta gttcaggatt
    55861 tttagcctcg atttggacct tggcacggct aacagcctct gcaacagtag gctctagcaa
    55921 gatgacattc cctttacgag tagagagctt cttcccttct tttgtaacca gaccaaaagg
    55981 aacgtgggta atgtcgtcac tccaatcgta gcccatctct tgcaagacag ctttgagttg
    56041 tttaaagtgg gcagattgct cttgaccaac gacgtagata gatttagcaa attggtattc
    56101 atttttacgg tagagggctg cagccaagtc acgtgtgata tagagagttg caccatcaga
    56161 cttcttgatg agggctggat gttcaattcc atatttctca agattcacaa cttgggcacc
    56221 ttctgattca agaagtagtc ctttttcaga aagaatgtct acaactgcat ccatcttatc
    56281 attgtagaag gcttctccgt tatagctgtc aaattcaacc ttcaattcat tgtaaaggcg
    56341 gttaaattcc actaaacttt catcgcggaa ccattgccaa agagcgagag cttcctcatc
    56401 tccattttca agtttacgga accattcgcg cgcttcttca tccaagctag ggtcattttc
    56461 agcttcagcg ttgatgcgga catagagttt aaggagttca tcgattggat gagcttttac
    56521 agcttcttcg tcgccccatt ttttataggc aacaatcaac atcccaaatt gtttacccca
    56581 gtctcccaaa tggttgacct tgaccgtttg ataaccgatt ttttggaaaa tatgtgacaa
    56641 gctatctccg ataacagttg aacgcaggtg gccaatagaa aatggtttag cgatattcgg
    56701 actagacatg tcgataacaa cattttcttg tttaccaata ttttggtcag catagtgttc
    56761 tttttcagtg gtaacagctt gcaatacttg agcagaaatg gcagatttat caaggaaaaa
    56821 gttaacgtaa ggtcctgttg cgacaacttt ttcaaaggct tggctgttca ttttttcagc
    56881 cagttcagcc gcaatcattt gtggtgcttt acgttcgact tttgcaagag aaaaagcagg
    56941 gaaagcaatg tctcccattt ctgagttttt aggggtttcc agtaacttta aaacagcctc
    57001 ttggtccagg ctatcaatga tgctagataa ttcgctagca atcaattctt ttgtattcat
    57061 taagagctcc tttttggact tttctactat tttatcacaa ttttaaagaa agaagaaaaa
    57121 atttttgaaa tctcctgttt ttttggtata atatggttat aaatatagtt ataaatatgc
    57181 acgcaagagg attttatgag aaaaagagat cgtcatcagt taataaaaaa aatgattact
    57241 gaggagaaat taagtacaca aaaagaaatt caagatcggt tggaggcgca caatgtttgt
    57301 gtgacgcaga caaccttgtc tcgtgatttg cgcgaaatcg gcttgaccaa ggtcaagaaa
    57361 aatgatatgg tgtattatgt actagtaaat gagacagaaa agattgattt ggtggaattt
    57421 ttgtctcatc atttagaaag tgttgcaaga gcagagttta ccttggtgct tcataccaaa
    57481 ttgggagaag cctctgtttt ggcaaatatt gtagatgtaa acaaggatga atggatttta
    57541 ggaacagttg ctggtgccaa taccttattg gttatttgtc gagatcagca cgttgccaaa
    57601 ctcatggaag atcgtttgct agatttgatg aaagataagt aaggtcttgg gagttgctct
    57661 caagacttat ttttgaaaag gagagacaga aaatggcgat agaaaagcta tcacccggca
    57721 tgcaacagta tgtggatatt aaaaagcaat atccagatgc ttttttgctc tttcggatgg
    57781 gtgattttta tgaattattt tatgaggatg cggtcaatgc tgcgcagatt ctggaaattt
    57841 ccttaacgag tcgcaacaag aatgccgaca atccgatccc tatggcgggt gttccctatc
    57901 attctgccca acagtatatc gatgtcttga ttgagcaggg ttataaggtg gctatcgcag
    57961 agcagatgga agatcctaaa caagcagttg gggttgttaa acgagaggtt gttcaggtca
    58021 ttacgccagg gacagtggtc gatagcagta agccggacag tcagaataat tttttggttt
    58081 ccatagactg cgaaggcaat caatttggcc tagcttatat ggatttggtg acgggtgact
    58141 tttatgtgac aggtcttttg gatttcacgc tggtttgtgg ggaaatccgt aacctcaagg
    58201 ctcgagaagt ggtgttgggt tatgacttgt ctgaggaaga agaacaaatc ctcagccgcc
    58261 agatgaatct ggtactctct tatgaaaaag aaagctttga agaccttcat ttattggatt
    58321 tgcgattggc aacggtggag caaacggcat ctagtaagct gctccagtat gttcatcgga
    58381 ctcagatgag ggaattgaac cacctcaaac ctgttatccg ctacgaaatt aaggatttct
    58441 tgcagatgga ttatgcgacc aaggctagtc tggatttggt tgagaatgct cgctcaggta
    58501 agaaacaagg cagtcttttc tggcttttgg atgaaaccaa aacggctatg gggatgcgtc
    58561 tcttgcgttc ttggattcat cgccccttga ttgataagga acgaatcgtc caacgtcaag
    58621 aagtagtgca ggtctttctc gaccatttct ttgagcgtag tgacttgaca gacagtctca
    58681 agggtgttta tgacattgag cgcttggcta gtcgtgtttc ttttggcaaa accaatccaa
    58741 aggatctctt gcagttggcg actaccttgt ctagtgtgcc acggattcgt gcgattttag
    58801 aagggatgga gcaacctact ctagcctatc tcatcgcaca actggatgca atccctgagt
    58861 tggagagttt gattagcgca gcgattgctc ctgaagctcc tcatgtgatt acagatgggg
    58921 gaattatccg gactggattt gatgagactt tagacaagta tcgttgcgtt ctcagagaag
    58981 ggactagctg gattgctgag attgaggcta aggagcgaga aaactctggt atcagcacgc
    59041 tcaagattga ctacaataaa aaggatggct actattttca tgtgaccaat tcgcaactag
    59101 gaaatgtgcc agcccacttt ttccgcaagg cgacgctgaa aaactcagaa cgctttggaa
    59161 ccgaagaatt agcccgtatc gagggagata tgcttgaggc gcgtgagaag tcagccaacc
    59221 tcgaatacga aatatttatg cgcattcgtg aagaggtcgg caagtacatc cagcgtttac
    59281 aagctctagc ccaaggaatt gcgacggttg atgtcttaca gagtctggcg gttgtggctg
    59341 aaacccagca tttgattcga cctgagtttg gtgacgattc acaaattgat atccggaaag
    59401 ggcgccatgc tgtcgttgaa aaggttatgg gggctcagac ctatattcca aatacgattc
    59461 agatggcaga agataccagt attcaactgg ttacagggcc aaacatgagt gggaagtcta
    59521 cctatatgcg tcagttagcc atgacggcgg ttatggccca gctgggttcc tatgttcctg
    59581 ctgaaagcgc ccatttaccg atttttgatg cgatttttac ccgtatcgga gcagcagatg
    59641 acttggtttc gggtcagtca acctttatgg tggagatgat ggaggccaat aatgccattt
    59701 cgcatgcgac caagaactct ctcattctct ttgatgaatt gggacgtgga actgcaactt
    59761 atgacgggat ggctcttgct cagtccatca tcgaatatat ccatgagcac atcggagcta
    59821 agaccctctt tgcgacccac taccatgagt tgactagtct ggagtctagt ttacaacact
    59881 tggtcaatgt ccacgtggca actttggagc aggatgggca ggtcaccttc cttcacaaga
    59941 ttgaaccggg accagctgat aaatcctacg gtatccatgt tgccaagatt gctggcttgc
    60001 cagcagacct tttagcaagg gcggataaga ttttgactca gctagagaat caaggaacag
    60061 agagtcctcc tcccatgaga caaactagtg ctgtcactga acagatttca ctctttgata
    60121 gggcagaaga gcatcctatc ctagcagaat tagctaaact ggatgtgtat aatatgacac
    60181 ctatgcaggt tatgaatgtc ttagtagagt taaaacagaa actataaaac caagactcac
    60241 tagttaatct agctgtatca aggagacttc tttgacaatt ctccactttt ttgctagaat
    60301 aacatcacac aaacagaatg aaaaggagct gacgcattgt cgctcccttt tgtctatttt
    60361 ttaaggagaa agtatgctga ttcagaaaat aaaaacctac aagtggcagg ccttggcttc
    60421 gctcctgatg acaggcttga tggttgctag ttcacttctg caaccgcgtt atctgcagga
    60481 agtattagac gccctcctta ctgggaaata tgaagctatt tatagtatcg gggcttggtt
    60541 gattggtgtg gccgtagtcg gtctagttgc tggtggactc aatgttgtcc tcgcagccta
    60601 tattgcccaa ggagtttcat ccgaccttcg ggaggatgcc ttccgtaaaa ttcaaacctt
    60661 ttcttatgct gatattgaac aatttaatgc gggaaatcta gtcgttcgaa tgacaaatga
    60721 tatcaaccag attcagaacg ttgtcatgat gaccttccaa attcttttca gacttcccct
    60781 cttgttcatc ggttcgttta tcctagcggt tcaaacctta ccttctctgt ggtgggtgat
    60841 tgttctcatg gtagtcttga tttttggttt gactgctgtc atgatgggaa tgatggggcc
    60901 tcgttttgcc aagtttcaaa cccttcttga gcgcatcaat gccattgcca aggaaaattt
    60961 acgtggcgtt cgtgtggtca agtcctttgt ccaagaaaaa gagcaatttg ctaagtttac
    61021 agaggtctca gacgagcttt ttggtcaaaa cctttacatt ggttatgcct tttcagtagt
    61081 ggaacccttt atgatgttgg ttggttacgg ggcggtcttc ctctctattt ggctggtcgc
    61141 gggaatggtt cagtcggatc cgtctgttgt tggttccatc gcttcttttg ttaattacct
    61201 aagccagatt atctttacca ttgttatggt tggatttttg ggaaattctg tcagccgtgc
    61261 catgatttcc atgcgtcgta ttcgagaaat tcttgacgca gagccagcta tgaccttcaa
    61321 ggatatccca gatgaagagt tggttggaag ccttagcttt gaaaatgtga cctttaccta
    61381 tccaatggac aaggaaccga tgctgaaaga tgtgagcttt actattgaac ctggtcaaat
    61441 ggttggtgta gttggagcga ctggtgcagg aaagtcaacc ttggctcaat tgattccacg
    61501 tctctttgat ccacagaacg gggccattaa aatcggtggc aaggatattc gagaagtgag
    61561 tgaaggaacc ctgcgtaaaa cagtttccat cgttctccaa cgtgccattc tttttagtgg
    61621 aacgattgca gataacttga gacaggggaa gggaaatgct actctatttg aaatggagcg
    61681 cgcagccaat attgcccagg ctagtgaatt cattcatcgt atggagaaaa cctttgaaag
    61741 tccagttgaa gaacggggaa ccaatttctc tggtggacaa aaacaaagga tgtcgattgc
    61801 gcgtgggatt gtcagcaatc cacgtattct gatttttgat gattcgacct cagccttgga
    61861 tgccaaatca gagcgcttgg tgcaagaagc tttgaataag gacttgaagg ggacgacaac
    61921 cattattatt gctcaaaaaa ttagctcggt tgtccatgca gacaagatct tggttctaaa
    61981 tcaaggacga ttgattggtc aaggtacgca tgcagacttg gttgccaaca atgccgttta
    62041 ccgtgaaatc tatgaaacac agaaatgaaa gacaaactat aagaaaagtc aatagtttta
    62101 tctaaactat ttcttatttc aatttgatga tttggcgatg attttagagc acggcaaaag
    62161 gcccttgaaa aagtccattt tttcaaaggt aatcctgtgt taatttcaga aattacatca
    62221 ctttttgttc gtcaaatggc agctcttttt ttaggatata aaacagggtt cggataagtt
    62281 tttttgcaag gtggatgatg gctacattgt aatgttttcc ttgttctaat ttagtcttaa
    62341 gataggcctt aaaagcaggc gaaaagcgag ggcatgcttt ggcagcttgt atgagtacct
    62401 accgcagatg aggggaactc cgtttgacca ttcttcctgc taaatcaatc tgatctgact
    62461 gataaataga agaatccagt ccagcgaaag cttgtaattg agcaggatta tcaaaggcat
    62521 gaatatttcg aatctcagct aaaatgaccg cccctaaacg atccccaatc ccagtaaccg
    62581 tcgtgatgac cgagttgaac tcagccatca agtcattgac acatgtttcc gccttgtcaa
    62641 tgagcccctt gtaatgtttg atgttttcat tacacgagat aaaacgtcta tgcgttatca
    62701 aactcattac caattaaaac aaaaagctgt ggttagatcc tttcggaaat tgtcaagcga
    62761 ttggaggaaa tgaactaatc cacagcggct tattccaagt ataccacttg ggctttggca
    62821 gtagctaact gcgctaaata taatataagg aggagtaaaa tgaagacagt tcaatttttt
    62881 tggcattatt ttaaggtcta caagttctca tttgtagttg tcatcctgat gattgttctg
    62941 gcgacttttg cccaagccct ctttccagtc ttttctggac aagcggtgac gcagctagcc
    63001 aatttagttc aagctcatca aaatggcaat ccagaacttg tatggcaaag cctatcagga
    63061 atcatggtca atcttggcct gctggttttg gttctattta tctctagtgt aatatacatg
    63121 tgtctcatga cgcgcgtgat tgcagaatcg accaacgaga tgcgcaaagg tctctttggt
    63181 aagcttgctc agttgacggt ttctttcttt gaccgtcgac aagatggcga tatcctgtct
    63241 cattttacca gtgatttgga taatatcctc caagccttta acgaaagctt gattcaggtc
    63301 atgagcaata ttgttttata cattggtctg attcttgtca tgttttcgag aaatgtgacg
    63361 ctggctctca tcaccattgc cagcacccca ttggctttcc ttatgctgat tttcatcgtg
    63421 aaaatggcac gcaaatacac caacctccag cagaaagagg tagggaagct caacgcctat
    63481 atggatgaga gcatttcagg ccaaaaagcc gtgattgtgc aaggaattca agaggatatg
    63541 atggcaggat ttcttgaaca aaatgagcgc gtgcgcaagg caacctttaa aggaagaatg
    63601 ttctcaggaa ttcttttccc tatcatgaat gggatgagcc tgattaatac agccatcgtc
    63661 atctttgctg gttcggctgt acttttgaat gataagtcta ttgaaacaag tacagcccta
    63721 ggtttgattg ttatgtttgc acaattttca cagcagtact accagcctat tatccaagtt
    63781 gcagcgagtt ggggaagcct tcagttggcc tttactggag ctgaacgaat tcaggaaatg
    63841 tttgatgcag aggaggaaat ccgacctgaa aaggctccaa ccttcactaa gttgcaagaa
    63901 agtgttgaaa tcagtcatat cgatttttca tacttgcctg ataaacctat tttgaaagat
    63961 gtcagcattt ctgcccctaa aggccagatg acagcagttg ttgggccgac aggttcagga
    64021 aaaacgacta ttatgaacct catcaatcgc ttttatgatg ttgatgctgg tggtatttat
    64081 tttgatggta aagacattcg tggctatgac ttagatagtc ttagaagcaa ggtgggaatt
    64141 gtattgcaag attcggtctt gtttagcgga acgattcgag acaatatccg atttggtgtg
    64201 ccagatgcta gtcaggaaat ggttgaggta gcagcaaaag caacccacat tcacgactat
    64261 atcgaaagtt tgcctgataa gtacgatact cttattgatg atgaccagag catcttttca
    64321 acagggcaga agcaattgat ttcaatcgct cgaaccctga tgacagatcc agaagttctc
    64381 attctcgatg aagcaacttc aaacgtagat acggtgacag aaagcaagat tcagcatgcc
    64441 atggaggtgg ttgtagcagg tagaactagt ttcgtcattg cccaccgctt gaaaaccatt
    64501 ctcaatgcag atcagattat tgtccttaaa gatggagaag tcattgaacg tggtaaccac
    64561 catgaacttt tgaagctagg tggcttttat tcagaactct atcacaatca atttgttttc
    64621 gaataagaaa gaagttgtcc tatgtgggca gctttttctt gtccataaaa aatgtttatc
    64681 acagccttaa aaaaaacata ttagacgaaa gtcattttga gtgatatgat aggactatcg
    64741 ttagcattcg aaaggagagg catcatggct agaacggttg taggagttgc tgcaaatcta
    64801 tgtcccgtag acgcagaagg caaaatcatt cattcatctg tatcttgtag attcgcagag
    64861 atcattcgtc aagtcggtgg tctcccttta gtcattcctg ttggtgatga gtcagttgta
    64921 cgtgattatg tggaaatgat tgacaaactc attttgacag gaggccaaaa tgttcatcct
    64981 cagttttatg gagagaagaa gaccgtcgag agcgatgatt acaatctggt ccgtgacgaa
    65041 tttgaattgg cactcttgaa ggaagcgctt cgtcagaata aaccaattat ggcaatctgt
    65101 cgcggtgtcc aacttgtcaa tgttgccttt ggtggaaccc tcaatcaaga aatcgaaggt
    65161 cactggcaag gactaccttt cgggacatct cactctattg agacagtaga aggaagcgtg
    65221 gtggctaagc tatttgggaa agaaagtcag gtcaactcag tccatcgtca aagcattaaa
    65281 gatttggcac ctaatttccg tgtaactgct attgattcaa gagaccaaac tattgaagcg
    65341 attgagtcta tcgacgagca ccgcattatc ggtttacagt ggcatccaga gtttctggtt
    65401 aatgaagaag atggcaattt agaattattt gagtatttat tgaatgaact gtaacgattg
    65461 gaacatctgg tcgttctttc ttttattttt tcaaaatttt tagaatgtgg cattttacgc
    65521 aaacgtttga attctgataa aaattggaga aattcgacaa aaaaacttga aaaaaacgaa
    65581 ggtaagcgtt atgatagaaa agaagaaata ttggaggaag aacatgtcac atattaaatt
    65641 tgattattca aaagttttag acaaatttgt tgcaccacat gaagtggaat acatgcaatc
    65701 acaagtaaca gcagcagatg aattgatccg taaaggaact ggtgctggta gcgacttctt
    65761 gggatggttg gaccttcctg aaaaatacga ccgcgaagaa tttgaccgca tcttgaaagc
    65821 tgctgagcaa atcaagtcag acagcgatgt tttggttgtg atcggtattg gtggatctta
    65881 ccttggtgca aaagcagcaa tcgacttctt gaatcaccat tttgctaact tgcaaacaaa
    65941 agaagaacgc aaagctccac aaatccttta cgcaggaaac tcaatctcat ctacttacct
    66001 tgctgacttg gtagagtatg ttgcagacaa agacttctca gtaaacgtaa tttctaaatc
    66061 aggtacaaca actgaaccag cgattgcttt ccgtgtcttt aaagaactct tggttaagaa
    66121 atacggtcaa gaagaagcta acaaacgtat ctatgcaaca actgaccgcc aaaagggtgc
    66181 tgttaaggtt gaagcagacg ctaacggttg gggaacattt gttgttccag atgatatcgg
    66241 tggacgcttc tcagtattga cagccgttgg tttgcttcca atcgcagcat caggagctga
    66301 cataaaagct cttatggaag gtgcgaatgc agctcgcaaa gactacactt cagacaaaat
    66361 ctctgaaaac gaagcttacc aatacgcagt cgttcgtaac atcctttatc gtaaaggcta
    66421 tgcaactgag atcttggtaa actatgagcc atcacttcaa tacttctcag aatggtggaa
    66481 acaattggct ggtgaatcag aaggaaaaga ccaaaaaggt atctacccaa cttcagccaa
    66541 cttctcaact gacttgcact cacttggtca atttatccaa gaaggaactc gtatcatgtt
    66601 tgaaacagtt gtccgtgttg acaaacctcg taaaaacgtg cttattccta ctttggaaga
    66661 agaccttgac ggacttggtt accttcaagg aaaagacgtt gactttgtaa acaaaaaagc
    66721 aactgacggt gttcttcttg cccacacaga tggtgatgta ccaaacatgt atgtgactct
    66781 tccagagcaa gacgctttca ctcttggtta cactatctac ttcttcgaat tggcaattgc
    66841 cctttcaggt tacttgaatg ctatcaaccc atttgaccaa ccaggtgttg aagcttataa
    66901 acgtaacatg tttgcccttc ttggaaaacc aggatttgaa gaattgagca aagaacttaa
    66961 cgcacgtcta taatagaaga aaagagtggt ttgcccactc tttttactct ctttatccat
    67021 agaaattgga ctcagccaag acttgtgata taatatagaa agcaaaaagg cagacgccta
    67081 gataatagga gaaactatgt caaaagatat ccgcgtacgt tacgcaccaa gtccaacagg
    67141 actactacac atcggaaatg cccgtacagc attgtttaac tacttgtatg cgcgccatca
    67201 tggtggaaca tttctcatcc gtatcgaaga tactgaccgt aaacgccatg tcgaggatgg
    67261 tgaacgttca caacttgaaa accttcgctg gttaggcatg gattgggatg aaagtccaga
    67321 atcacatgag aattatcgcc agtctgagcg tttggacttg tatcaaaaat acatcgacca
    67381 actattagct gaaggaaaag cctacaaatc ttacgttaca gaagaagagt tggcagctga
    67441 acgtgaacgt caagaagtag ctggcgaaac accacgctac atcaatgaat accttggtat
    67501 gagtgaagaa gaaaaagcag cttacatcgc agaacgtgaa gcagcaggga tcatcccaac
    67561 tgttcgtttg gctgtcaatg agtcaggtat ctacaagtgg catgatatgg tcaaaggcga
    67621 tatcgaattt gaaggtggca atatcggtgg tgactgggtt atccaaaaga aagacggtta
    67681 cccaacttac aactttgccg ttgttatcga tgaccacgat atgcaaatct ctcatgttat
    67741 ccgtggagat gaccatattg ctaatacacc aaaacagctt atggtctatg aagctcttgg
    67801 ttgggaagct ccagagttcg gtcacatgac cttgattatc aactctgaga ctggtaagaa
    67861 gttatctaaa cgtgatacta atacacttca atttatcgaa gattaccgaa agaaaggtta
    67921 ccttccagaa gcagtcttta actttattgc tcttcttggt tggaacccag gtggtgaaga
    67981 tgagattttc tctcgtgaag aactcattaa actttttgat gaaaaccgcc tcagcaagtc
    68041 accagcagcc tttgatcaga aaaaactaga ctggatgagc aatgattata tcaagaatgc
    68101 agaccttgaa accatctttg aaatggcaaa accattctta gaggaagcag gccgtttgac
    68161 tgacaaggct gaaaaattag ttgagctcta taaaccacaa atgaaatcag tagatgagat
    68221 tatcccattg acagatcttt tcttctcaga tttcccagaa ttgacagaag cagagcgcga
    68281 agtcatgacg ggtgaaacag ttccaacagt tcttgaagca ttcaaagcaa aacttgaagc
    68341 gatgacagat gataaatttg tgacagaaaa tatcttccca caaattaaag cagttcaaaa
    68401 agaaacaggt attaaaggga aaaatctttt catgcctatt cgtatcgcag tttcaggcga
    68461 aatgcatggg ccagaattac cagatacaat tttcttgctt ggacgtgaaa aatcaattca
    68521 gcatatcgaa aacatgctaa aagaaatctc taaataaaga ggatacaata atggacatct
    68581 gggaaaagat gtacgaagaa gcacagaaac tatacaatcc acatgaagta tcagactttg
    68641 tttatgccaa tcatgttgta gctgcagtag aagcagaaga tggacaaata tttacaggat
    68701 tctgtatgga gggaacctgt ggtgttttcc atctctgcgc agaacgggcg accctcttca
    68761 atatgtacca attttcagga caaactaagg ttaagaaagt attagccttt cgagacaaac
    68821 caccttatgg tggaagttca gccatgcctt gcggtgcttg tagagaattc cttttagagc
    68881 ttaatgctga aaataaagat gcagaattca tgatggacta taatataaga aaaacagtta
    68941 aagtcgcaga actaatccct tattggtggg gagaagaacg tgcttctaag tttaatgagc
    69001 gatagaagag tcagtataat tctggctttt tttactataa gttgaaaaaa t
//
LOCUS       DAVLHM010000004        56448 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLHM010000004 DAVLHM010000000
VERSION     DAVLHM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.004"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(90..287)
                     /locus_tag="VXE45_000284"
     CDS             complement(90..287)
                     /locus_tag="VXE45_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0788388.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(362..1138)
                     /locus_tag="VXE45_000285"
     CDS             complement(362..1138)
                     /locus_tag="VXE45_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0788389.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1260..2006
                     /locus_tag="VXE45_000286"
     CDS             1260..2006
                     /locus_tag="VXE45_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0788390.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2019..2999
                     /locus_tag="VXE45_000287"
     CDS             2019..2999
                     /locus_tag="VXE45_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0788391.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3194..3514
                     /locus_tag="VXE45_000288"
     CDS             3194..3514
                     /locus_tag="VXE45_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0788392.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3560..3868
                     /locus_tag="VXE45_000289"
     CDS             3560..3868
                     /locus_tag="VXE45_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0788393.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3885..5183
                     /locus_tag="VXE45_000290"
     CDS             3885..5183
                     /locus_tag="VXE45_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0788394.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            5334..7772
                     /locus_tag="VXE45_000291"
     CDS             5334..7772
                     /locus_tag="VXE45_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0788395.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7791..8459
                     /locus_tag="VXE45_000292"
     CDS             7791..8459
                     /locus_tag="VXE45_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0788396.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            8477..9565
                     /locus_tag="VXE45_000293"
     CDS             8477..9565
                     /locus_tag="VXE45_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0788397.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            10047..12548
                     /locus_tag="VXE45_000294"
     CDS             10047..12548
                     /locus_tag="VXE45_000294"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0788398.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            12742..13437
                     /locus_tag="VXE45_000295"
     CDS             12742..13437
                     /locus_tag="VXE45_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788399.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13449..13865
                     /locus_tag="VXE45_000296"
     CDS             13449..13865
                     /locus_tag="VXE45_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788400.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(14492..14584)
                     /locus_tag="VXE45_000297"
     CDS             complement(14492..14584)
                     /locus_tag="VXE45_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0788401.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            14745..15716
                     /gene="ruvB"
                     /locus_tag="VXE45_000298"
     CDS             14745..15716
                     /gene="ruvB"
                     /locus_tag="VXE45_000298"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0788402.1"
                     /translation="MGDEELVEHTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            15697..16269
                     /locus_tag="VXE45_000299"
     CDS             15697..16269
                     /locus_tag="VXE45_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0788403.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            16500..17258
                     /locus_tag="VXE45_000300"
     CDS             16500..17258
                     /locus_tag="VXE45_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0788404.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            17267..18070
                     /locus_tag="VXE45_000301"
     CDS             17267..18070
                     /locus_tag="VXE45_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0788405.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            18092..19351
                     /gene="rseP"
                     /locus_tag="VXE45_000302"
     CDS             18092..19351
                     /gene="rseP"
                     /locus_tag="VXE45_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0788406.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            19364..21217
                     /locus_tag="VXE45_000303"
     CDS             19364..21217
                     /locus_tag="VXE45_000303"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0788407.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            21316..22707
                     /gene="bglA"
                     /locus_tag="VXE45_000304"
     CDS             21316..22707
                     /gene="bglA"
                     /locus_tag="VXE45_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0788408.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAVKVAYHTQLASSRAVKACHELLPD
                     SKIGIVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGL
                     LPDATEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEHYVMPGRK
                     INSHRGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRID
                     FVKGHLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKS
                     GHWFKELSDNNGF"
     gene            22900..24708
                     /gene="glmS"
                     /locus_tag="VXE45_000305"
     CDS             22900..24708
                     /gene="glmS"
                     /locus_tag="VXE45_000305"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0788409.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGFDVDKPRNLAKSVTVE"
     gene            complement(24846..24923)
                     /locus_tag="VXE45_000306"
                     /pseudo
     CDS             complement(24846..24923)
                     /locus_tag="VXE45_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            24980..26029
                     /locus_tag="VXE45_000307"
     CDS             24980..26029
                     /locus_tag="VXE45_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0788410.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLALLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(26129..29965)
                     /gene="spuA"
                     /locus_tag="VXE45_000308"
     CDS             complement(26129..29965)
                     /gene="spuA"
                     /locus_tag="VXE45_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0788411.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNKSDISSLGNANASLEKTEEKPATEPT
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQ
                     AEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISL
                     LALLGLGFLLKNKKEN"
     gene            30382..30795
                     /gene="rpsL"
                     /locus_tag="VXE45_000309"
     CDS             30382..30795
                     /gene="rpsL"
                     /locus_tag="VXE45_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0788412.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            30815..31285
                     /gene="rpsG"
                     /locus_tag="VXE45_000310"
     CDS             30815..31285
                     /gene="rpsG"
                     /locus_tag="VXE45_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0788413.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            31710..33791
                     /gene="fusA"
                     /locus_tag="VXE45_000311"
     CDS             31710..33791
                     /gene="fusA"
                     /locus_tag="VXE45_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0788414.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            33895..38286
                     /locus_tag="VXE45_000312"
     CDS             33895..38286
                     /locus_tag="VXE45_000312"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0788415.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREVFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            38388..38651
                     /locus_tag="VXE45_000313"
     CDS             38388..38651
                     /locus_tag="VXE45_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0788416.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            38644..38922
                     /locus_tag="VXE45_000314"
     CDS             38644..38922
                     /locus_tag="VXE45_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0788417.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            38943..39095
                     /locus_tag="VXE45_000315"
     CDS             38943..39095
                     /locus_tag="VXE45_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788418.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            39117..40358
                     /locus_tag="VXE45_000316"
     CDS             39117..40358
                     /locus_tag="VXE45_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0788419.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            40368..40598
                     /locus_tag="VXE45_000317"
     CDS             40368..40598
                     /locus_tag="VXE45_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0788420.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            40821..41543
                     /locus_tag="VXE45_000318"
     CDS             40821..41543
                     /locus_tag="VXE45_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0788421.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            41760..43094
                     /gene="pepC"
                     /locus_tag="VXE45_000319"
     CDS             41760..43094
                     /gene="pepC"
                     /locus_tag="VXE45_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0788422.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(43150..44061)
                     /locus_tag="VXE45_000320"
     CDS             complement(43150..44061)
                     /locus_tag="VXE45_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0788423.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(44085..44888)
                     /locus_tag="VXE45_000321"
     CDS             complement(44085..44888)
                     /locus_tag="VXE45_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0788424.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(44916..45905)
                     /gene="manX"
                     /locus_tag="VXE45_000322"
     CDS             complement(44916..45905)
                     /gene="manX"
                     /locus_tag="VXE45_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0788425.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(46138..47157)
                     /gene="adhP"
                     /locus_tag="VXE45_000323"
     CDS             complement(46138..47157)
                     /gene="adhP"
                     /locus_tag="VXE45_000323"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0788426.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(47496..48308)
                     /locus_tag="VXE45_000324"
     CDS             complement(47496..48308)
                     /locus_tag="VXE45_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0788427.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            48498..49916
                     /locus_tag="VXE45_000325"
     CDS             48498..49916
                     /locus_tag="VXE45_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0788428.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTKVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            49969..50676
                     /locus_tag="VXE45_000326"
     CDS             49969..50676
                     /locus_tag="VXE45_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0788429.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLMVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            50801..51745
                     /gene="folP"
                     /locus_tag="VXE45_000327"
     CDS             50801..51745
                     /gene="folP"
                     /locus_tag="VXE45_000327"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0788430.1"
                     /translation="MSSKANHAKTAICGIINVTPDSFSDGGQFFALEQALQQARKLIA
                     EGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAAL
                     AAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQTF
                     TEKELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLR
                     DLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQ
                     GVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            51747..53069
                     /locus_tag="VXE45_000328"
     CDS             51747..53069
                     /locus_tag="VXE45_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0788431.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLESIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEEKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGCFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            53050..53604
                     /gene="folE"
                     /locus_tag="VXE45_000329"
     CDS             53050..53604
                     /gene="folE"
                     /locus_tag="VXE45_000329"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0788432.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            53647..54459
                     /gene="folK"
                     /locus_tag="VXE45_000330"
     CDS             53647..54459
                     /gene="folK"
                     /locus_tag="VXE45_000330"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0788433.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(54610..54927)
                     /locus_tag="VXE45_000331"
     CDS             complement(54610..54927)
                     /locus_tag="VXE45_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0788434.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            55284..55730
                     /gene="rplM"
                     /locus_tag="VXE45_000332"
     CDS             55284..55730
                     /gene="rplM"
                     /locus_tag="VXE45_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0788435.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            55749..56141
                     /gene="rpsI"
                     /locus_tag="VXE45_000333"
     CDS             55749..56141
                     /gene="rpsI"
                     /locus_tag="VXE45_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0788436.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
BASE COUNT        16566 a        10370 c        12768 g        16744 t
ORIGIN      
        1 aaattaattt gactttcctg atagagatgt tcacatctta tttcaattca ctatattaga
       61 gtaaaattct ctacaaaaag aagaatagcc tatttgacta ttcttccgag tgatttcaat
      121 ttctttgggg aaatatggag atacttttta aatactttgg caaaatattt atagtctgaa
      181 aatccaactt ggtcagagat agcgcttaaa ggggagttgg gagattcagc catcttatct
      241 atagcttgtt tcaggcgata ttgtaagata tattcattta gagtcatggg gaagtcttct
      301 ttgataacct tatatagatg cttgttatct gcaaatagct agagcatttc aaggaaataa
      361 actagaaata acaattaata tggtggttca gaaatacctt ttgataatca ataagatctt
      421 caggatgaag tgcgttgatt ccatccattt catatttccg atttaataaa cgatatttgt
      481 tttcaccaaa ttgatgaaaa gggagtagtt gaacttggtc gatatttaat gagttaaata
      541 gagtagcgaa tttttctgca tcctctaaac tattgttaaa attaggaata actgggattc
      601 ttaaaacgat agttttattt tgagaaaaag cataatgaat gtttttaata atcatttgat
      661 taaaaacccc agtcactttt ttatgtttta tagaattata atgttttagg tctgtgtaga
      721 taaaatccac atattgaatt aaatcaataa atttttcatg atcaacaaag gcagtagttt
      781 caatggcagt gtgtatgtga tgttctttag ctgattttaa gatggcttta gcaaattcaa
      841 actgagcaaa tatttcacct cctgataaag ttaaacctcc accggattct tcgtaaaatt
      901 ctttgtcttt taatacctct gtaataattt cttctacagt cttttcttca ccgactaagg
      961 tgaatttctc tcgttgagca tctttcattt tttcaggttt cattctttga gattcaggat
     1021 tagaacacca tggacagcgc agaggacatc cttttaaaaa aacagttgta cgaatacccg
     1081 ggccgtcatg aattgaaaag tgttgaatat taaaaataat tcctttagat atttccataa
     1141 gagttcctcc tcttcataag tctatcctat cacaaaaacg aaagaaaaac aattacgaac
     1201 gaaagtttaa tttgttgttt tttgcttttt attttggtag aataaaacgg aggtgtaaaa
     1261 tgaaaagatt ggaacaaatt attaaattag tatcagaata tgaaaagatc gacgttaata
     1321 cattatcgga aaaattaaat gtatcgaaag taacgattag aaaagattta gataaattag
     1381 agtcaaaagg tttattacac agagagcatg gatatgctgt attaaatagt ggagatgact
     1441 taaatgtacg tttgtcaatt aactatgaaa ttaagagaaa aattgttcag gaagcagtaa
     1501 aattggtgtc agataatgaa acaataatga tagaatctgg atcgacctgt gctttacttg
     1561 ctgaggaaat ttgcaagcaa aaaagaaatg ttacgattgt aacaaattca ttttttatag
     1621 caaattttgt gagagcttat gattcatgtc gtattattgt tcttggtgga gagtttcaga
     1681 aggattcaca ggttactgtg ggacctttat taaaagaaat gatacagact tttcatgtgc
     1741 atcaagcttt tgttgggaca gatggttacg ataaagagat gggctttaca ggaaaagatt
     1801 taatgcgcag tgaggtagtt caatatattt cagcagcgtc ggataaagtc attgtactaa
     1861 ctgactcaag taaatttgat aaaaggggta cagtaagaag atttgcttta agtcaagtct
     1921 atgaagtaat aacagacgaa aaactttcta aacaaaatat agctacatta gaaaatgctg
     1981 ggataatggt taaggtagtt tcgtaagagg ttaaatgtat gaatcaagat aggaataaac
     2041 tgctctctaa aattgcttat ctgtattata ttgaaaactt aaatcagtca caaatagcag
     2101 caaaattagg aatttataga acctctatta gtagaatgtt aacagaagca aggaatgcag
     2161 gaattgttaa aattgaaata gagaattttg ataccaatat gtttaagttg gaaaattatg
     2221 taaaagaaaa atatggtctg gaaagtttag aaattattcc aaatgaattt gatgataatc
     2281 caacaatttt atctgaaaga atttctcaag ttgcagcagg tgtccttagg aatctaattg
     2341 atgataatat gaaaattggc ttttcttggg ggaaaagttt aagtaattta gtagatttaa
     2401 ttcacagtaa aagtgtccga aatgttcact tctatcctct agcaggtggt cctagtcaca
     2461 tacacgctaa ataccatgtg aatacactga tttatgaaat gtctagaaaa tttcatggag
     2521 agtgtacatt tatgaatgca acgattgtgc aagaaaataa attgttagca gatggtattt
     2581 tgcaatcaag atattttgaa aatttgaaaa atagttggaa agatttagat atagctgtag
     2641 tcggaattgg tgattttagc aataaaggga aacatcaatg gttagacatg cttacagagg
     2701 atgactttaa agaattgacc aaagttaaaa ctgtaggaga aatttgttgt cgattttttg
     2761 attcaaaagg taaagaagtc tatgaaaact tacaggaaag aacgatagcc atctctttgg
     2821 aagatttaaa aaatattcct caaagtttag ctgttgctta cggtgatacg aaagtatctt
     2881 cgattctttc tgtcttgcgt gctaatttag taaatcattt gattacagat aaaaatacaa
     2941 ttttaaaagt tttggaagaa gatggtgatt tgacttttag agagattcta ggtgagtgaa
     3001 aatgatagac tgatcagttt atcgtttttt ctttttagtc gattgcacat ttgtgcttat
     3061 ataaacaaaa atagtttatc tgttgttttt ggattgacaa ctttattatg tagttgtatt
     3121 ctatagttac aaaagaaaat tttaaaattt caaatgaaaa aagcttttta catagtgaaa
     3181 tgaggaggaa tttatggaaa ttattgttcc agatcaaatt atcatgggtt taattttata
     3241 tgctggcgat gcgaaacaac atatttataa agcattagat tacataaaaa atggtacatg
     3301 tgaacggtgt gaagaagaaa tccagttagc tgatgccgcc ttattagaag cccataatct
     3361 acaaacaaaa ttcttggcac aagaagcgtc tggtacaaag acagaaatta cagctctctt
     3421 tgttcattca caagatcatc tcatgactag catgacggag attaatttaa tcaaagaaat
     3481 tattagtttg agaaaagaac ttcataaaaa ataatactag agtattatca ttgttattaa
     3541 catagaggag gaaaacataa tggtgaagat tggtttgttt tgtgcagcag gtttttctac
     3601 tggtatgctt gtaaataata tgaaaattgc agcgcaatct agtggagttg aggcagaaat
     3661 agaggcgttt tctcagtcta aattagcgga ttatgcgcca aatatagatg ttgcactatt
     3721 gggtccacaa gttgcttata cattagataa atcaaaagaa atttgtgata agtgtgatgt
     3781 tccgatagct gttattccga tgatggacta tggtatgtta gatgggaaaa aagtattaga
     3841 tttggcccta tctttgatta gtgggtaaga aaaggagatt tattatgtca aagatggatg
     3901 ttcagaaaat cattgcaccg atgatgaagt ttgtgaatat gcgtggcatt atagctctaa
     3961 aagatgggat gttagcaatt ttgccattga cagtagttgg cagtttgttc ttgattatgg
     4021 gacaattgcc gttcgaagga ttaaataaga gcattgctag tgtttttgga gctaattgga
     4081 cagagccgtt tatgcaagta tattcaggaa cttttgctat tatgggtcta atttcttgtt
     4141 tttcaattgc ctattcttat gctaagaata gcggagtaga ggctttacca gctggagttc
     4201 tatctgtatc tgcattcttt attttgctaa gatcatctta tatccctaaa caaggtgagg
     4261 cgattgggga cgctattagt aaagtttggt ttggaggcca aggaattatc ggtgctatca
     4321 ttataggttt ggtagtagga agtatttata ccttctttat aaagagaaaa attgttatta
     4381 agatgccaga acaagttcca caagctattg ccaaacagtt tgaagcaatg attccagcat
     4441 ttgtaatttt cttatcttct atgattgtat atattttagc gaagtcattg actaatggcg
     4501 gaacattcat agaaatgatt tattctgcta ttcaagttcc gttgcaaggt ttaactggat
     4561 ctttgtatgg tgctattgga attgcattct ttatatcatt tttgtggtgg tttggtgttc
     4621 atgggcaatc ggtagtaaat ggagtagtga cagctctgct tttatctaat cttgatgcta
     4681 ataaagctat gttagcctct ggtaatctat cattagaaaa tggtgcacat attgttactc
     4741 aacaattttt agattcattt ttaattctat caggttcagg gattacgttt ggtcttgtag
     4801 ttgccatgct ttttgcagca aaatcaaaac aataccaagc cttaggaaaa gttgcagctt
     4861 ttccagcaat atttaacgta aatgagccag ttgtatttgg atttccgatt gtcatgaatc
     4921 cagttatgtt tgtacctttc attcttgttc ctgtacttgc agctgtgata gtatatggag
     4981 ctattgcaac aggtttcatg caaccattct caggggtaac attgccttgg agtacaccag
     5041 ctattctatc aggatttttg gtgggtggat ggcaaggtgt tgtgactcag ttattagtat
     5101 tggcgatgtc tacaatggtt tactttccat tctttaagat acaagatcgt ttagcttgcc
     5161 aaaatgaaat caaacaatct tagaggtatt tgtgtgttac tgttaaactc acacatttgt
     5221 gctaaaaatt agagagttaa aatttttcta gttaaaagct tgaaaatttc tataaaaatc
     5281 ggtattatat tttcgaaaga aataaaaata ttttcgaaag aaaggtgctt acgatggtaa
     5341 atacagaagt agcaagaaca acaatcaaga cagaatattt tggcagcctt actgaaagga
     5401 tgaacaaata tcgagaagat gttttaaata aaaaacctta tattgatgct gagagagcag
     5461 ttctagcaac acgcgcctat gaacgataca aggaacaacc taatgtccta aaacgtgcat
     5521 atatgctgaa agaaattttg gaaaatatgt ctatctatat tgaagaagaa tctatgattg
     5581 cgggaaatca agcttcttcc aataaagatg ctcctatttt tccggaatat acgctagaat
     5641 ttgttctcaa tgagttggat ctttttgaaa agcgtgatgg agatgttttc tatattacag
     5701 aagaaacaaa agaacaactt agaagtattg ctccgttttg ggaaaataat aatttacgtg
     5761 ctagagctgg tgccttatta cctgaagaag tgtctgttta tatggaaaca ggattcttcg
     5821 gtatggaagg taagatgaat tctggagatg ctcacttagc agttaactat cagaaacttt
     5881 tgcaatttgg tttaagaggt tttgaagagc gggctcgtaa agcgaaggta gctctagatt
     5941 taacagatcc agcaagtatt gataaatatc atttttacga ctctatattt atcgtaatcg
     6001 atgctattaa agtatatgca aagcgctttg ttgctcttgc taaaagttta gccgaaaatg
     6061 caaatcctaa acgtaagaaa gaattacttg agattgcaga tatttgctct agagtcccat
     6121 atgaaccggc aactactttt gcagaagcta ttcaatcagt ttggtttatt caatgtattt
     6181 tacaaattga atctaatggc cactctcttt catatggccg ttttgatcaa tatatgtatc
     6241 catatatgaa ggctgattta gaaagtggta aagaaacaga agatagcatt gttgaacgtc
     6301 tgacaaatct ttggattaag acaattacaa ttaataaggt tcgcagtcaa tcacatacat
     6361 tttcttcagc aggaagtcct ttatatcaaa atgttacaat tggtggacag actcgagata
     6421 agaaggatgc tgttaaccca ttatcttatt tggtattaaa atcagttgca caaacccatc
     6481 taccgcaacc taatctaact gtacgttacc atgcaggttt agatgctcgt ttcatgaatg
     6541 agtgtattga agtgatgaaa cttggttttg gtatgcctgc atttaataat gatgagatta
     6601 ttattccttc ttttattgca aaaggagtat tggaagatga tgcttatgat tacagtgcca
     6661 ttggatgtgt tgaaacggca gttccaggga aatggggcta tcgttgcaca ggtatgagtt
     6721 atatgaactt ccctaaggtt ctacttatca cgatgaatga tggaattgat ccggcttcgg
     6781 gtaaacggtt tgcaccaagc tttggtcatt ttaaggatat gaagaacttt tctgaattag
     6841 aaaatgcttg ggataaaaca ctaagatatt tgacacgaat gagtgttatt gttgaaaatt
     6901 ctattgattt atcattggaa cgagaagttc ctgatattct atgttcagca ttgactgatg
     6961 attgtattgg tcgtggaaaa caccttaaag aaggtggagc agtatatgat tatatatcag
     7021 gattgcaagt tggaattgca aatttgtcgg attcattagc tgcaattaaa aaattggtgt
     7081 ttgaggaaga acgtataagc ccaagtcagc tttggcatgc actggaaaca gattatgccg
     7141 gagaagaagg taaggtcatt caagaaatgt tgattcatga tgcacctaag tatggtaatg
     7201 atgatgatta tgctgacaaa ttggttactg ctgcttatga catttatgtt gatgaaattg
     7261 ctaaatatcc taatacacgt tatggaagag gtccaattgg aggaattcgt tattcaggaa
     7321 catcttctat ctcagccaac gtagggcagg gacgtggaac attagcaact ccagatggac
     7381 gcaacgcggg tacaccgtta gcagagggtt gttcaccatc acataatatg gatcaacacg
     7441 gccctacatc tgttttaaaa tctgtttcaa aattaccaac agatgaaatc gtaggtgggg
     7501 ttctcttaaa tcagaaagta aatcctcaaa cgttagccaa agaagaagat aaattaaaac
     7561 taattgcttt gttacgaaca ttctttaatc gtttacatgg gtaccatatt caatacaatg
     7621 ttgtttccag agagacgctg attgacgctc agaaacatcc tgaaaaacac agagacttaa
     7681 ttgttcgtgt tgcaggatac tctgcattct tcaatgttct ttctaaggca acccaagatg
     7741 acattatagg acgtactgag catactttgt aaaataaaga ggttcttttt atggaattta
     7801 tgcttgacac attaaattta gatgagatta aaaagtggtc tgaaattttg ccgctagctg
     7861 gggtaacttc aaatcccact attgcaaaaa gagagggttc tattaatttt tttgaacgaa
     7921 tcaaagatgt aagagaattg attggctcta caccctctat tcatgttcag gtgatttctc
     7981 aagattttga aggcatctta aaggatgctc ataaaattcg aagacaagca ggagatgata
     8041 tatttatcaa agtacctgtt actccagctg gattacgtgc aataaaggcg ctaaaaaaag
     8101 agggctacca tatcactgca acagctattt atacagttat tcagggatta ttagctatcg
     8161 aagcaggagc ggattaccta gctccatatt ataatagaat ggaaaatctg aacattgatt
     8221 caaattctgt cattcgtcaa ttagctcttg ctattgatag acagaactct cctagtaaga
     8281 ttttagctgc atcctttaaa aatgtagcac aagtaaataa tgctttagct gcaggtgcgc
     8341 atgctgttac agcaggagcg gatgtttttg aatcagcttt cgccatgcca tctatccaaa
     8401 aggcggttga tgatttttct gacgattggt ttgttattca aaatagtcgt tccatttaga
     8461 tagagaggaa atacatatga gaatttttgc tagtccttct agatatattc agggggaaaa
     8521 tgccttgttt gaaaatgcca aatcaatttt ggatttggga aattgcccta ttctattatg
     8581 cgatcagttg gtttatgata ttgttggaaa acgatttgaa gattacctac ataggtatgg
     8641 tttccatatt gttctggcgc tatttaatgg tgaagcttct gacaatgaaa tcaatcgagt
     8701 tgttgccttg gctgagaaag aaaattgtga tagtattatc ggtcttggtg ggggaaagac
     8761 gattgatagc gcaaaagcta ttgcagattt gattgaaaag cctgttatta ttgctccaac
     8821 aattgcatcg accgacgcac ctgtatctgc tttatctgtt atttatacag atgaaggtgc
     8881 atttgatcat tatctatttt attctaaaaa tccagattta gttttggttg atacaaaagt
     8941 tatttcacaa gcccctaagc gtttattagc gtctggtatt gcagatggtt tagcaacttg
     9001 ggttgaggcg cgtgcggtta tgcaggcaaa tggaaaaact atgttgggac aacagcaaac
     9061 attggctgga gttgcaattg cgaagaaatg tgaagaaacg ctgtttgcag atggtttaca
     9121 ggctatggca gcttgtgaag ctaaagtggt gacaccagca ttagaaaata ttgttgaagc
     9181 taatacttta ttgagtggtc taggttttga aagtggagga ttagctgcgg cgcatgcaat
     9241 tcataatggt tttactgcat tgacaggtga cattcatcat ttaacacatg gtgaaaaagt
     9301 agcttatgga actttagtac aactattatt ggaaaataga cctaaagaag aacttgataa
     9361 gtatattgag ttttacaaaa aaattggtat gccaacaact ctaaaagaaa tgcatttgga
     9421 tcaagttgga tatgatgatt taataaaagt tggtaaacaa gcaactatgg agggtgagac
     9481 aattcatcag atgccgttta agatttcgcc ttcagatgtt gctcaagcta ttatcgctgt
     9541 agatgcctat gtaaattcaa aataaacaat aaggactact gttttccaaa tggtagtctt
     9601 ttattgatcc ctgtattgaa ttctatagaa gattgaaata ggatgagaac aaatcgattg
     9661 ggaaagtaaa attaatttct ataaatgttt tagcaattgt ttcgtactat ttcagattca
     9721 gtctactata tgttcttcat aaatcaaaaa gcgacatagg ttgtcggcaa tcaaaaagcg
     9781 acataggttg tcggctattt attgtgaata cattaattag cattccagtt ttatcttcgg
     9841 tctaaaataa gtattttgtg ctatacgaga taagcttctt gacttactcc ttgatttact
     9901 gcataacaat gggataaaaa gtgggagata gagcaattca tagtcatcaa aattaatgag
     9961 atacagtata cagtttttcc tttaaacaca tttcaaattc cctcaaaaat ggtataatag
    10021 taacatcaca aaattggaga gagaccatga gtttttacaa tcataaagaa attgagccta
    10081 agtggcaggg ctactgggca gaacatcata catttaagac aggaacagat gcatcaaaac
    10141 ctaagtttta tgcgcttgat atgttccctt atccgtctgg agctggtctg cacgtaggac
    10201 acccagaagg ttatactgca accgatatcc tcagtcgtta caaacgtgcg caaggctaca
    10261 atgtccttca cccaatgggt tgggatgctt ttggtttgcc tgcagagcaa tacgctatgg
    10321 atactggtaa tgacccagca gaatttacag cggaaaacat tgccaacttc aaacgtcaaa
    10381 ttaatgcgct tggattttct tatgactggg atcgtgaagt caacacaaca gatccaaact
    10441 actacaagtg gactcaatgg attttcacca agctttacga aaaaggcttg gcctatgaag
    10501 ctgaagtgcc agtaaactgg gttgaggaat tgggaactgc cattgccaat gaagaagtgc
    10561 ttcctgacgg aacttctgag cgtggaggct atccagttgt ccgcaaacca atgcgccaat
    10621 ggatgctcaa aatcacggct tacgcagagc gcttgctcaa tgacttagat gaactagatt
    10681 ggtcagagtc tatcaaggat atgcaacgca actggattgg taaatcaact ggtgccaatg
    10741 taactttcaa agtaaaagga acagacaagg aatttacagt ctttactact cgtccggaca
    10801 cacttttcgg tgcgactttc actgtcttgg ctcctgaaca tgaattagta gacgctatca
    10861 caagttcaga gcaagcagaa gctgtagcag actataaaca ccaagccagc cttaagtctg
    10921 acttggctcg tacagacctt gctaaagaaa aaacaggggt ttggactggt gcttatgcca
    10981 tcaaccctgt caatggtaag gaaatgccaa tctggattgc agactatgtc cttgctagtt
    11041 atggaacagg tgcggttatg gctgtgcctg cccacgacca acgtgactgg gaatttgcca
    11101 aacaatttga ccttccaatc gtcgaagtac ttgaaggtgg aaatgtcgaa gaagctgcct
    11161 acacagagga tggcctgcat gtcaattcag acttcctaga tggactcaac aaagaagacg
    11221 ctattgccaa gattgtggct tggttggaag aaaaaggctg tggtcaggag aaggttacct
    11281 accgtctccg cgactggctc tttagccgtc aacgttactg gggtgagcca attccaatca
    11341 ttcattggga agatggaact tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc
    11401 ctgtaaccaa ggatatccgt ccttcaggta ctggtgaaag tccactagct aacttgacag
    11461 attggcttga agtgactcgt gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc
    11521 cacaatgggc tggttcaagc tggtactacc tccgctatat tgatccacac aatactgaga
    11581 agttggctga tgaggacctc ctcaaacaat ggttgccagt agatatctac gtgggtggtg
    11641 cagagcatgc tgttcttcac ttgctttacg ctcgtttctg gcacaaattc ctctatgacc
    11701 tcggtgttgt tccgactaag gaaccattcc aaaaactctt taaccaaggg atgattttgg
    11761 gaacaagcta ccgtgaccac cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg
    11821 atggttcctt cttccatgta gaaacagggg aagagttgga gcaagcgcca gccaagatgt
    11881 ctaaatcgct caagaacgtt gttaacccag acgatgtggt ggaacaatac ggtgccgata
    11941 cccttcgtgt ttatgaaatg tttatgggac cactcgatgc ttcgattgct tggtcagaag
    12001 aaggtttgga aggaagccgt aagttccttg accgagttta ccgtttgatt acaagtaaag
    12061 aaatccttgc ggaaaacaat ggtgctcttg acaaggttta caacgaaaca gtcaaagctg
    12121 ttactgagca aattgagtct ctcaaattca acacagctat tgcccaactt atggtctttg
    12181 tcaatgctgc taacaaggaa gataagcttt atgttgacta tgccaaaggc tttattcaat
    12241 tgattgcacc atttgcacct cacttggcag aagaactctg gcaaacagtc gcagaaacag
    12301 gtgagtcaat ctcttatgta gcttggccaa cttgggacga aagtaaactg gttgaagacg
    12361 aaatcgaaat cgttgtccaa atcaaaggta aagtccgtgc caaactcatg gtcgctaaag
    12421 acctatcacg tgaagaattg caagaaattg ctctagcgga tgaaaaagtc aaagcagaaa
    12481 ttgacggtaa ggaaatcgtg aaagtgatta gtgtaccaaa taaattggtt aatattgttg
    12541 taaaataacc aatttatttg ctgatttcca acctcaaaca gtttcccaaa ctgtttgagc
    12601 caactaaact cgttaatatc gttgtgaaat aaggtaggaa tccttcagag tagaatctgg
    12661 aggatttttt gaatcttctt atgaaagtat ggtatactat gggcaactat aaagtttgaa
    12721 aagtgaaaaa aggagaaagc tatgccagta aatgaatatg gtcaaatgat tggggagtca
    12781 atggaaggtt atacaccagg tgaactgcct tctattgatt tcttagaagg gcgttatgct
    12841 aggatagagg ctctttcagt ggaaaagcat gcggaggatt tgctagctgt ttatgggcct
    12901 gatacgcctc aggagatgtg gacctacctt tttcaggagc cagtagcaga tatgggggag
    12961 ctggttagcc ttttacatca gatgttggct cgtaaggacc gtttttacta tgcaatcata
    13021 gacaaggcga ctggtaaggc tttgggatct ttttctctca tgcgcattga ccagaataac
    13081 cgagtaatag aagtcggagc agtcactttt tctccagagc taaggggtac acggatagga
    13141 actgaagctc agtatctcct agctcgctat gtttttgagg agctaaacta tcgtcgctac
    13201 gagtggaaat gcgatgcctt aaatctgcca tccagacgag ctgcggagcg tttgagcttt
    13261 atttatgaag gaaccttccg tcaggcagtg gtttataagg gacgtacgag agatacggat
    13321 tggttgtcta tgattgataa ggactggcct caagtcaaag atcgtttgga aacatggttg
    13381 cgtcctgaaa attttgataa aaatggacag cagtacaaga gcttgagaga actttaagag
    13441 gtgttgacat gattactatt aaaaagcaag aaattgtcaa gctagaggat gttttacatc
    13501 tctatcaggc tgtcggttgg acaaattata cccatcaacc agagatgctg gagcaggcct
    13561 tatctcattc attagtaatt tatctggcac ttgatggtga tgctgtggtg ggcttgattc
    13621 gtttggttgg agatggattc tcatcagtat tggttcagga tttaatcgtt ttaccaatct
    13681 atcagcgtca aggaattggt agtgccttga tgaaagaggc tttagaggat tacaaagatg
    13741 cctatcaagt ccagctggtg acagaagaga cagaaagaac cttgggcttc tatcgttcta
    13801 tgggctttga aatcttatcc acctataatt gtatagggat gacttggatg aatcgtaaaa
    13861 aataacaaaa cttgtttttt cttaagcaaa atttaaggat ggtctagtat tatatagtca
    13921 ttaaataaag acctcctaac tttatttaat aaaatcctaa acttttcttt ttcataataa
    13981 tctcccttaa ctccacccaa tcaggtggag ttttttagct ctatttcagg cttttgggga
    14041 ctattctaaa aataattttt cgatattttt cggtattttt cggattttgg tcggggaatt
    14101 ggcggggact tttttagcga atataactaa gaaataggtc tgtggtcgct tcagctagtt
    14161 caaactcaat ttgattgtaa gtgactgtta attgaagaac tggaactact gtaataatga
    14221 ttttgcttgt ctagtagtgg cgtattaaat gagaagtgac atgtaagatt gtctcttcgt
    14281 ttacgaaatc aaaatttcta tgaaattgat agaatcccta acgttctctt aatcttaacc
    14341 gtcttgtcgt acagcggttg aagaaaatgt aaacctttga caaaattcgt gaactatgag
    14401 ataataaaaa ggaattgagt actagttcta tatcataggc tagaaaagac cccaagctca
    14461 cgaccaaata agcttggggt cttttttgac actatttgtc cttgtttagc catttatcga
    14521 ctatacgaag aacgacaccg accacaattg gtccgatgat agttttgagt actaattcca
    14581 tcatgggcta tctcacctcc tttcgtaggc ggtgtagcag tgtcgtagaa tattatacca
    14641 cataagtgct aaacttagga gtcacccaat caggtggctt ttttgtttgt ggcttggttt
    14701 tttgatataa tagagccatg agtagaattt tagataatga gataatgggg gatgaggagt
    14761 tagtagaaca cacgctccgt cctcagtatt tacgtgaata tatcggacag gataaggtca
    14821 aggaccagct acaaatcttt attgaagctg ccaaaatgcg ggatgaagcg ctggatcatg
    14881 tgctcttatt tgggcctcca ggtctcggga aaacgaccat ggcctttgtt attgccaacg
    14941 aactgggagt caatcttaag cagacgtcgg gtccagtcat tgaaaaagcc ggagatctgg
    15001 tagctatttt gaatgagtta gagcctgggg atgtactttt tattgatgag atccatcgtt
    15061 tgccaatgtc agtggaagag gtgctttata gtgctatgga ggacttctac atagatatta
    15121 tgattggggc tggtgagggt agtcgtagtg ttcatttgga gttaccacct tttaccttga
    15181 ttggtgcgac gactcgggct ggtatgctct ccaatccgct acgggcacgt tttgggatta
    15241 caggccatat ggagtattat gcccatgctg acttgacaga aattgtcgag cggacggcag
    15301 atatttttga gatggaaatc actcatgagg cagcatctga gttggcccta cgtagtcgtg
    15361 ggacccctcg tattgccaat cgtctcctca agcgcgtgcg cgattttgcc cagataatgg
    15421 ggaatggggt aattgatgat attattaccg ataaggcttt gactatgctg gatgttgacc
    15481 atgaaggttt ggactatgtg gatcaaaaaa tccttcgtac catgattgag atgtacagtg
    15541 gaggacctgt tggtctagga actctttctg tgaatatcgc cgaagagcgt gagacagttg
    15601 aagatatgta tgagccttac ttgattcaaa aaggttttat catgcggaca cggtctggac
    15661 gggtggcgac tgctaaggca tatgagcact taggttatga atacagtgaa aaataagcaa
    15721 gaaatcttag aggcttttag agaaaatcca gatatgatgg ccattctgac gatcatccga
    15781 gaccttggtc tgaaagactc gtggttggca gcaggttctg tcagaaattt catttggaat
    15841 cttttgtcag acaaatcccc ttttgatcat gaaacagata tagatgtgat tttctttgat
    15901 ccagattttt cttatgagga aaccttatta ctggagaaaa agctgcgaga ggattttcct
    15961 cagtaccagt gggaattgaa aaatcaggtc tatatgcatc agcacagtcc tcacactgct
    16021 tcctatacca gttctcgtga tgctatgagt aagtatccag aacggtgtac gacagttgga
    16081 ctgcgcttga atgaagaatc agattttgaa ctctatgcac cttatggttt ggaggatatt
    16141 ttgaattttc aagttcgtcc aactcctcat ttcttagaaa atgaagaccg aatggaactc
    16201 tatcaaacac gtttatccaa gaaaaattgg caggagaaat ggaaaaattt gatttttaaa
    16261 aatacttaag gaaactttaa gctagggagt gtacactaag ttcataagtt aagaagacct
    16321 taacttaaac tcctaaaact ttttcataat aatctcccta taaaaataaa gtcgcccaat
    16381 caggcggctt atttttttga aaaatgggct tggtgcctga gaataaatag cttagtgata
    16441 gaagaaaatg gggaaatatg gtataataaa acgatagatt tttgaatagg aataagatca
    16501 tgtttggatt ttttaagaaa gataaggctg tggaagtaga ggttccgaca caggttcctg
    16561 ctcatatcgg catcatcatg gatggcaatg gccgttgggc taaaaaacgt atgcaaccgc
    16621 gagtttttgg acataaggcg ggcatggaag cattgcaaac cgtgaccaag gcagccaaca
    16681 aactgggcgt caaggttatt acggtctatg ctttttctac ggaaaactgg acccgtccag
    16741 atcaggaagt caagtttatc atgaacttgc cagtagagtt ttatgataat tatgtcccgg
    16801 aactacatgc gaataatgtt aagattcaaa tgattgggga gacagaccgc ctgcctaagc
    16861 aaacctttga agctttaacc aaggctgagg aattgactaa gaacaacaca ggattgattc
    16921 ttaattttgc tcttaactat ggtggacgtg ctgagattac acaggcgctt aagttgattt
    16981 cccaggatgt tttagatgcc aaaatcaatc caggtgacat cacagaggaa ttgattggta
    17041 actatctctt tacccagcat ttgcctaagg acttacgaga cccagacttg attatccgta
    17101 ctagtggaga attgcgtttg agcaatttcc ttccatggca gggagcctat agtgagcttt
    17161 attttacgga caccttatgg cctgattttg acgaagcggc cttgcaggaa gctattcttg
    17221 cctataatcg tcgtcatcgc cgatttggag gagtttagga ggaaatatga cccaggattt
    17281 acagaaaaga accttgtttg cagggattgc cctggctatt ttcctaccaa ttttaatgat
    17341 tgggggcctc ttgcttcaga tagcaatcgg aatcatagcc atgctagcca tgcatgaact
    17401 tttgaagatg agaggtctag agaccatgac gatggagggc ctcttgaccc tctttgcaac
    17461 ctttgcattg accattccct tggagaatta cctgactttt ttgccagttg atgggaatgt
    17521 ggttgcctat agtgttttga tttcaatcat gttaggaacg accgttttta gcaagtctta
    17581 tacgattgag gatgcggttt tccctcttgc tatgagcttc tacgtgggct ttggatttaa
    17641 tgctttacta gatgctcgtg ttgcaggttt ggacaaggct ctcttagcct tgtgtatcgt
    17701 ctgggcgaca gacagtggtg cctatcttgt tgggatgaac tatgggaaac gaaagttagc
    17761 accaagggta tcgcctaata aaacccttga gggtgccttg ggtggtattt taggagcaat
    17821 tttagtaacc attatcttta tgatagttga cagtacagtt gctcttccat atggaattta
    17881 caagatgtca gtctttgcta ttttctttag cattgctgga caatttggtg atttactaga
    17941 aagttcgatc aaacgtcatt ttggtgttaa ggattctggg aaatttatcc ctggacatgg
    18001 tggtgttttg gatcgtttcg atagtatgtt gcttgtattt ccaatcatgc acttatttgg
    18061 actcttttaa tcaaaagacg gaggaaacgc tatgctcgga attttaacct ttattctggt
    18121 tttcgggatt attgtagtgg tgcacgagtt cgggcacttc tactttgcca agaaatcagg
    18181 gattttagta cgtgaatttg ccatcggtat gggacctaaa atttttgctc acattggcaa
    18241 ggatggaacg gcctatacca ttcgaatctt gcctctgggt ggctatgtcc gcatggccgg
    18301 ttggggtgat gatacaactg aaatcaagac aggaacgcct gttagtttga cacttgctga
    18361 tgatggtaag gttaaacgca tcaatctctc aggtaaaaaa ttggatcaaa cagccctccc
    18421 tatgcaggtg acccagtttg attttgaaga caagctcttt atcaaaggat tggttctgga
    18481 agaagaaaaa acatttgcag tggatcacga tgcaacggtt gtggaagcag atggtactga
    18541 ggttcggatt gcacctttag atgttcaata tcaaaatgcg actatctggg gcaaactgat
    18601 taccaatttt gcaggtccta tgaacaattt tatcttaggt gtcgttgttt tttgggtttt
    18661 aatctttatg cagggtggtg tcagagatgt tgataccaat cagttccata tcatgcccca
    18721 aggtgccttg gccaaggtag gagtaccaga aacggcacaa attaccaaga ttggctcaca
    18781 tgaggttagc aactgggaaa gcttgatcca agctgtggaa acagaaacca aagataagac
    18841 ggcaccgact ttggatgtga ctatttctga aaaggggagt gacaaacaag tcactgttac
    18901 acccaaagat agtcaaggtc gttaccttct aggtgttcaa ccgggggtta agtcagattt
    18961 tctatccatg tttgtaggtg gttttacaac tgctgctgac tcagctctcc gaattctctc
    19021 agctctgaaa aatctgattt tccaaccaga tttgaacaag ttgggtggac ctgttgctat
    19081 ctttaaggca agtagtgatg ctgctaaaaa tggaattgaa aatatcttgt acttcttggc
    19141 aatgatttcc atcaatattg ggatttttaa tcttattccg attccagcct tggatggtgg
    19201 taagattgtg ctcaatatcc tagaagccat ccgccgcaaa ccattgaaac aagaaattga
    19261 aacctatgtc accttggccg gagtggtcat catggttgtc ttgatgattg ctgtgacttg
    19321 gaatgacatt atgcgactct tttttagata atcgaggaat attatgaaac aaagtaaaat
    19381 gcctatccca acgcttcgcg aaatgccaag cgatgctcaa gttatcagcc atgctcttat
    19441 gttgcgtgct ggttatgttc gccaagtttc agcaggtgtt tattcttatc taccacttgc
    19501 caatcgtgtg attgaaaaag ctaaaaacat catgcgccaa gaattcgaaa agattggtgc
    19561 tgttgagatg ttggctccag cccttcttag tgcagaattg tggcgtgaat caggtcgtta
    19621 cgaaacctat ggtgaagacc tttacaaact aaaaaaccgt gaaaaatcag actttatctt
    19681 aggtccaact cacgaagaaa cctttacagc tattgtccgt gattctgtta aatcttacaa
    19741 gcaattgcca ctcaaccttt atcaaattca gcccaagtat cgtgatgaaa aacgcccacg
    19801 taatggactt cttcgtacac gtgagtttat catgaaggat gcttatagtt tccacgctaa
    19861 ctatgatagt ttggatagtg tttatgatga gtacaaagca gcctatgagc gtatttttac
    19921 tcgtagtggt ttagacttca aggctattat tggtgacggt ggagccatgg gtggtaagga
    19981 tagccaagaa tttatggcca ttacatctgc tcgtacagac cttgaccgct gggttgtctt
    20041 ggacaagtca gttgcctcat ttgacgaaat tcctgcagaa gtgcaagaag aaatcaaggc
    20101 agaattgctc aaatggatag tctctggtga agataccatt gcttactcaa gtgagtctag
    20161 ctatgcagct aacttagaaa tggcaacaaa cgagtacaaa ccaagcaacc gtgttgtcgc
    20221 tgaagaagaa gttactcgtg ttgcaacgcc agatgttaaa tcaatagatg aagttgcagc
    20281 tttcctcaat gttccagaag aacaaacgat taaaaccctc ttctacattg cagatggtga
    20341 gcttgttgca gcccttctag ttggaaatga ccaactcaac gaagtcaagt tgaaaaacca
    20401 cttaggagca gatttctttg acgttgctag cgaagaagaa gtggcgaatg ttgttcaagc
    20461 aggatttggt tcacttggac cagttggttt gccagagaat attaaaatta ttgcagatcg
    20521 taaggtgcaa gatgttcgca atgcagttgt cggtgctaac gaagatggct accacttgac
    20581 tggtgtgaac ccaggccgtg attttacttc agaatatgtg gatatccgtg aagttcgtga
    20641 gggtgaaatt tccccagatg gacaaggtgt ccttaatttt gcgcgtggta ttgagatcgg
    20701 tcatattttc aaactcggaa ctcgctattc agcaagcatg ggagcagatg tcttggatga
    20761 aaatggtcgt gctgtgccaa tcatcatggg atgttacggt atcggtgtca gccgtcttct
    20821 ttcagcagtg atggagcaac acgctcgcct ctttgttaac aaaacgccaa aaggtgaata
    20881 ccgttacgct tggggaatca atttccctaa agaattggca ccatttgatg tgcatttgat
    20941 tactgttaat gtcaaggatg aagaagcgca agccttgaca gaaaaacttg aagcaagctt
    21001 gatgggagct ggttatgaag tcttgacaga tgaccgtaac gaacgtgtcg gtgttaaatt
    21061 tagcgatagt gacttgattg gtcttccaat ccgtatcact gttggtaaaa aagcggccga
    21121 tggcattgta gaagttaaga tcaaggcaac tggtgacacc attgaggttc atgcagataa
    21181 cgtgcttgaa acgcttgaaa tcctaagtaa gaaataaaaa ctataatcag aagaaaaaca
    21241 aggaaaaaat gtaactagtt tttaccttgt tttttctgta taatgggaga aatgagtaga
    21301 taaagaggta aatgtatgct aagatttcca aaggattttg tctggggatc ctctacttct
    21361 ggaccgcaga cagaaggacg tgtagctggt gacggtaagg gagacaatct ctgggattac
    21421 tggttccaag tggagccaaa tcgttactat aatgggattg gttcagataa gacatcgact
    21481 ttttatgaaa attgggagcg ggatattgag cttttgttag agactggtca cacagccttt
    21541 cggacttcta ttcagtggtc acggattttt ccacaaggct gtggaaaagt caaccctcaa
    21601 ggtgtggatt tttatcgtaa ggtctttgag gctattaagg ctaaaggaat tcgtctgtta
    21661 gtcaatctct atcattttga tttacctttt gcccttcaag aggatggtga tggttgggaa
    21721 aataaggcga cagtttcagc ctatgaagac tatgctcgtt tttgttttga gacttatgga
    21781 gatttagtgg atcaatggat tacctttaac gagcccatcg ttcctgtaga atttggttat
    21841 ttttatgatg cccattatcc acataaggtg gatgcagagg cagctgttaa ggtagctgtt
    21901 aaggtagcct atcatacaca attggccagc agccgggctg ttaaggcttg ccatgaactt
    21961 ttgcctgatt ccaagattgg gattgtcctc aacttgacac cggcttatcc acgtagccag
    22021 catcctgctg atgtcaaggc agctcgtatt gcggcccttt ttcaggccca atctttctta
    22081 gatccatctg tcttggggac ttatccacag gagttggtag aaatcttgca tgaacacggt
    22141 cttttacctg atgctacaga ggaagagttg gaactcattc gtgataatac ggtggacttc
    22201 cttggtgtga actactatca acctttgcgt gttatggctc ctcgatttgc taagcatcca
    22261 gagagtccac tcttaccaga acatttttac gagcattatg tgatgcctgg acgtaaaatc
    22321 aattctcacc gtggttggga gatttatgag caagggattt atgacatcgc ccaaaatatc
    22381 aaggaaaatt atggcaatat tgagtggatg ttgactgaga atggtatggg tgttgaaggg
    22441 gaagaaaaat tccgtcaaga tggaatgatt caagatgatt accgtattga ctttgtaaaa
    22501 ggtcatcttc gtgaacttca ccgtgccatt gaagatggtg ccaactgtaa gggctacttg
    22561 atttggacct ttattgactg ctggtcatgg ctcaacagct ataaaaatcg ctatggtttg
    22621 gtcgaattag acttggaaac gcaagaacgt cgtctgaaga aatcaggcca ctggttcaaa
    22681 gaattaagcg ataataatgg attttaaaaa ggactctgac tgattatccc aatcggtcag
    22741 agtttttatg cttacaggag cttaatttga actataccaa tttttactct tgacaagtga
    22801 aagaaacaag tatatactgt ttttactgat tctataaaag atgaattaga ctataccaat
    22861 tttaaggaga aagcacagct tgcctgtgtc gtatatacta tgtgtggaat tgttggtgtt
    22921 gttggaaaca caaatgcaac tgatattttg attcaagggc ttgaaaagct tgaataccgt
    22981 ggctatgatt ctgcgggaat ttttgtccta gatggtgctg ataaccattt ggtgaaggcg
    23041 gttggtcgta ttgcagaatt gtctgccaag acagctggtg ttgagggaac aactggtatc
    23101 ggacatactc gttgggctac tcacggaaaa ccaactgagg acaatgctca cccacaccgc
    23161 tctgagacag aacgttttgt cttggtgcat aatggggtga ttgagaacta tcttgaaatc
    23221 aaggaagaat accttgcagg tcaccacttc aaggggcaga cagatactga aatagccgtt
    23281 catttgattg gaaaatttgc ggaagaagaa gggctctcag ttcttgaagc cttcaaaaaa
    23341 gctcttcata ttatccgtgg ttcatatgcc tttgccttga ttgactctga aaatccagat
    23401 gtcatctatg tagcgaaaaa caaatctcca cttttgattg gtcttgggga aggctacaat
    23461 atggtctgct cagatgctat ggctatgatt cgtgaaacca accaatacat ggaaattcat
    23521 gaccaagagt tggtaatcgt caaggctgat agcgtggaag ttcaagacta tgatggtaac
    23581 agtcgtgaac gtgctagcta tactgcggaa cttgacttgt cagatatcgg taagggaact
    23641 tatccttact acatgcttaa ggaaattgat gagcaaccaa ctgttatgcg taaactcatt
    23701 caagcctaca cggatgatgc tggtcaagta gtgattgatc ctgctatcat taaggctgtt
    23761 caagacgcag accgcatcta catccttgca gctggaacat cttaccatgc aggatttgct
    23821 tctaagaaaa tgttggaaga attgacagat acaccagttg aacttggaat ctcatctgag
    23881 tggggctacg gtatgccact tctcagcaag aaaccactct tcatctttat cagccaatct
    23941 ggtgaaacag cggatagtcg tcaagttttg gtcaaggcta atgaaatggg aattccaagc
    24001 ttaacagtga caaacgttcc aggttcaacc ctctcacgtg aagccaacta taccatgctc
    24061 cttcacgcag gtcctgaaat tgccgtggca tcaactaaag cctatacagc gcaaatcgca
    24121 gcccttgcct tccttgcaaa agcagtcgga gaagcaaatg gtaatgctaa agcgcaagcc
    24181 tttgacctgg ttcatgaatt gtcaatcgta gctcagtcta tcgaatcaac tctttcagag
    24241 aaagaaacca ttgaagccaa ggttcgtgaa cttcttgaaa caactcgtaa cgccttttac
    24301 atcggacgtg gtcaagatta ctacgtagcc atggaagcaa gtctcaaact caaagagatt
    24361 tcttatatcc agtgtgaagg ttttgcggca ggagaactca agcacggaac cattgccttg
    24421 attgaagaag gaacgcctgt cttgtctctc ttgtcagatc cagttcttgc caaccatact
    24481 cgtggaaata tccaagaggt cgcagcccgt ggtgccaaag tcctcactat cgcagaagag
    24541 aatgtagcca aagataccga cgatatcgtc cttacgaccg tacatccata cctctcacca
    24601 atttcaatgg tcgtaccaac gcaattagtc gcttactttg caaccctcca ccgtggcttc
    24661 gatgtggaca aaccacgtaa ccttgccaag tcagtaacgg tagaataagc taaaaaagtc
    24721 tagttatcta ggcctttttc ttgtgagcaa attggttgct tgtactcaag attcgtgtta
    24781 tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtaggt atggttactg
    24841 acttcgtcag ttctatccac aacctcaaaa cactgttttg agcagcctgc agctagcttc
    24901 ctagtttgct ctttgatttt cattgagtat tagaataatt tttcaaattg aagtacagag
    24961 atagataagg agaatcacaa tggtagaatt gggaatttca acatttgggg aaataacgga
    25021 gcttgaaggg actggacaaa cttacagtca tgctgaacgc attcgccagt tggtggcaga
    25081 gattgagctg gctgacaagg ttggtttgga tgtatatggg attggtgagc accatcgggc
    25141 ggattttgca gtatcagccc cagagattgt tctggccgct ggggcagtca ataccaagaa
    25201 aatccgtttg accagtgcag tcagcattct gtcaagcatg gacccgattc gtttgttcca
    25261 acagtatgcc actatcgatg ctttgtcaaa tggacgagcg gagattatgg ctggaagggg
    25321 ctctttcacg gaatctttcc ctctgtttgg ttatgacttg aaagactacg actctctttt
    25381 tgatgagaaa ttagccttgc ttcagttagt caatgaaaag accaagttag actggcaagg
    25441 tcgattgact caaacgattg ctggtaaaga agtttatcct cgtccagttc aggacaaatt
    25501 gcccttgtgg atagctacag gtggtcatgt cgaatcaaca gtgaagattg ctcaggctgg
    25561 tctaccgatt gtatatgcta ttattggtgg taatccacgt tattttaaaa agttgattca
    25621 ggcttatcgt gagattggaa gcgaagcggg tcatgctgac aaagacttga aagtgggagc
    25681 ccattcttgg gggtggattg cggaagatgg tgagcaggcg gtgaaagatt atttccatcc
    25741 gactaagcaa gtggtggatg ctatttccaa agaccgtccg cactggcagg aattgcgtta
    25801 tgagcaatat ttggagcagg tagggccaaa tggcgccatg tttgttggca atccagatca
    25861 ggtggccgaa aaattgattc gcatgataga ggatttagga ttggaccgct tcatgcttca
    25921 tctaccgctt ggttctatgc ctcatgacca ggttctgaga gctattgaac tcttcggaac
    25981 acaagttgca cccaaagtac gagcttattt tgctatgaaa gaggcttaat aaaaaatcct
    26041 aatcaagttt attaggacaa caaatattgt acgaaaatta atcccccgag ctataatgct
    26101 tgggggattt ttctatagga gggctagttt agttctcttt tttatttttt agtaagaaac
    26161 cgagaccaag gagcgcaagg aggctgattc ctgcaaatag gagtttgttt tcgtttttga
    26221 ttcctgtatt tggaagttca gcttgtctat ctggggttgc aggtatattt ttcttgctag
    26281 agttttctac cgattcgttt tgaaccgctt cttttacaga tgatgcttgt gcttcttgtg
    26341 ctggttgttc agcttgtgaa tcagctgtag cttggctagg tttattttcc gcatcagcta
    26401 ctttggcatc tggtttagta gaatcaggtc tagcttctgg agctgggtct tgatgttcag
    26461 gcttggaagg ggttgagtct ggtttctctt ctgcagttga ctcatggcta gttccatttt
    26521 gagagactcg aagaacagta gctgtaaggg cattcaattt caagcctttt tcagtccatt
    26581 caagtccttt cgggttggca attccgactg gtcctgcttg gttttcatct gccaaaactt
    26641 ccgcatttct tagatgtgca aaggcagttc ccaaattaaa ttcgcgagct ttttcatccg
    26701 cattgacaaa gactgcgtag atatcgccgt ttggagcagt gatttggtag ccaatcacta
    26761 catcctcttt ttccacacca ttttggcctg ggacagtgat gaggtggaca cggtctttga
    26821 tatcttggag actcttaagt cggaaggcat ctgtagattg acgaagggca atcaaacctt
    26881 tcatatagtc acggctcttg acattttcag gataagcttt accatctgta gccttagtcc
    26941 agtcaaactt gttgactgcg tcgctagaat cgtaagaatc atggatgaag taaggatagt
    27001 caaatgggtt gccgtcctta tcacgcaaca agtgagattt gtttggaacc ttatcctctg
    27061 ctactggagt cttgtaggct gggtcacgga attgtttagt acgtccatat tcctgaccgg
    27121 agtggataaa tggagttcct tgagctgtca agaccatgag atttccaagt cgtaaacgac
    27181 ggtggatttc agcatagttc tcagccttgc ttgggtcttt tttgatagac tgggcaatga
    27241 tgtcaaagag ggtcaagtta tcatgggctg cgatgtattg gatgacatct ccagggctgt
    27301 cagcttcaaa gttagttggt tgagcaatga gatttttaaa gatggtgttg acatcacgct
    27361 tgccacctgt gataaaggca ggttgacctt cgtttggata accagatttg aggttgttac
    27421 ggatgtcatc tgaaaagaca gcgacagtat cggtatgttt catccaatct tggtcagcag
    27481 ctttagtagg catgttttca tcaccggcat aggttctcca accttcgcct aacatgatta
    27541 gatttggatt gagggcgcgt gcagccttgt aagcttcttc gatagaagcg gcgtcatggt
    27601 ctcccatcat atcgaagcgg aagccatcca ctttgtaggt atcaactagg tatttgatag
    27661 agtcaactag gaggcgtttg gtcatatggt gggttgtccc caagcgtcca ccaccaaagc
    27721 tagttcgagg tgtgccatcg gcatccataa agtggtagta gtttggctct aggtcttcaa
    27781 agatatcgac tttggctgtg tggttataaa cgacatctag gatagctccc ataccacgtt
    27841 tgtggatttc gttgatgagg tttttaaatt ctgcgattcg tttttctgga ttcttaggat
    27901 cgcttgagta cataccagtc aaggagaagt agttttgagg gtcatatccc cagttgtagt
    27961 tgctgttgct tgaagcatag tcagacaagc gttcatggtt tttcaattca ttgacaaagt
    28021 agtaagacaa gactggaagg agctggatat gggttacacc caagtctttg agatagtcta
    28081 gtttttcaat gaaggcttca aaagtcccaa atggtttggt caagtctttt gcaatggcag
    28141 gatctgaagt gaagtcacgc acatgagctt cgtagataac ggcgtcttca cgagtcttga
    28201 aattgtgaat cttaccataa gtcaagtctt gaggtccgag tttagctgga tctacaaagg
    28261 cggctttagc cactttatgg gcatcgtcaa tcttggcatc gttgctattc caagcagcaa
    28321 gagatttagc gtaaggatcg agtgcaagaa cagttttacc ttgacgctcg atttggtatt
    28381 gataatagta gccagtgaaa tctgtgattc cgagtttgtt tgtgctgtct agagtttgtt
    28441 tccaagttcc tctttcccct ttttcgagag cgacagttcc aactactttg tcagggtcat
    28501 tcttgtcgta gacaacaaca gaaaccttat cagcacttgg tgaccaaagg gtcaaatcaa
    28561 cttgttttcc ttcttctttt aggtcagctc ccagtttgcc atcatagctg tatgtctcat
    28621 ctttcaggcg ccagcttgtt ttggtagtga attggtcgga attgtagcta acagtataag
    28681 gatgttttgt gtcagagaaa tctccgctgt aggtcacttt cttaccagct tcatcgattg
    28741 caacatcggt aatagttacc ttgtttccta ggtgattagt gatgttggag tgtttgagga
    28801 tatcttcttt tttagcaccg acaagtgttg aaaagctact ttcaatgcta gaagtgccta
    28861 cgtgttgggc tcctgtcata cggatatcat ggacatagta tggatttgtg taaatcgatt
    28921 catcatcgtc ttttaggaaa atttggctat gatttttcaa atctgtgaac ttataatttt
    28981 ctttacggat tttcacgtcg tctccttgtt tgctctcatc tagtaataaa aatccaaatt
    29041 ctcttgcggc ttcattaaga ggaatgtcga tatagcggcc atatttgcct gtagccgtaa
    29101 agtctgttcc gtcaggccat tgagcgctac ttggattttt cacatctccc cagtaccaga
    29161 gagatttctt gtcatagttg ccatctgtgc ggtagtagtt gacgcgaaca gttcctgcag
    29221 gctgtggctc gtaagagaaa accttgtaat cttggtctaa ccaagcttcg ttcatttttg
    29281 gaactagttt ttctacagat ttatcgccgg ttagattttt tccagctgta ttgttgatga
    29341 ggaagctaat tttcttggct tgttctccct ttaatttgac atctaggtaa tagccgtagt
    29401 catctttctt ggcatccttg aaggacaaag ctccgtttgg ccagttttca gatggttttt
    29461 caacatcgtc ccaagtccat agtccttgag catccttgtt ttcttcagga agttttttga
    29521 catggatacg gaagtagtta tcttcgatgg gctcttctgc cttagtttca gttgttactg
    29581 gactagtaga agtagttggc tcacttgaac gatcttgtcc agtttgtggt gctggatcgg
    29641 ctgggcttgc agcaggagtt gttggctctg ttgcaggttt ttcttctgtt ttctctaggg
    29701 aagcgtttgc atttccaagt gaagaaatat cacttttgtt cttaccagag ccagctgctg
    29761 tatcagtaag aggttgggca agggtggttg tatttctgtt gttgggttcg ttagtggttg
    29821 gtgtactttc gtcggatgag atagttggtg tagccatggc aagcaagaca aggcttgcgc
    29881 cgataaggac agaaccagtc ccatttttga gggaacggat gctgtagacc atttttttct
    29941 cagtgtgaga tggtgttttt ctcataatga ttctccaatc aataaatttc tatatcagta
    30001 tagcatgtag taaaacaata tgcaagcgtt ttctttgatt tgtgaaaaaa attcttactt
    30061 ttgagaagtt ttctgtacta ttttatatat cagtataaat gacggagata aaaatgtcac
    30121 ataagccaag ccgtattatt aggaagatga tgtgttccca gctattttta ttcagaaatt
    30181 gatctctaac attaccaata aaaaagaaaa atatcttgac aaacaaggga aaattttgtt
    30241 acaataatag acggtacttt ttacttttgg tctctcaaga gtgtacaggg acgtgctgac
    30301 aaatgttgca aaagtacaca cagatgatat ctgtcaccaa gtgtatcatc accaaaaata
    30361 aaaaaacaca ggagaatgta gatgcctaca attaaccaat tggttcgcaa accgcgtaaa
    30421 tcaaaagtag aaaaatctaa atcaccagct ttgaacgttg gttacaatag tcataaaaaa
    30481 gttcaaacaa acgtttcttc accacaaaaa cgtggtgttg caactcgtgt tggaacaatg
    30541 acacctaaaa aacctaactc agcccttcgt aaattcgctc gtgtacgttt gagcaacctt
    30601 atcgaagtta ctgcctacat cccaggtatc ggacacaact tgcaagagca cagcgtggtg
    30661 cttcttcgcg gtggacgtgt aaaagacctt ccaggggtac gttaccatat cgtccgtggt
    30721 gcacttgata ctgcaggtgt taacgatcgt aaacaaggtc gttctaaata cggtactaaa
    30781 cgtccaaaag cataaggaaa ggggataaag agaaatgagt cgtaaaaata gagctccaaa
    30841 acgtgacgta ttgccagatc cgctatacaa ttcacaacta gttactcgtc ttatcaaccg
    30901 cgttatgctt gatggtaaac gtggtactgc tgcttcaatc gtttacggtg cttttgagca
    30961 aatcaaagaa gctactggca acgatgcact tgaagtattt gaaacagcta tggaaaacat
    31021 catgcctgta cttgaagtac gtgcacgtcg tgttggtggt tctaactacc aagtcccagt
    31081 tgaagttcgt ccagaacgtc gtacaacact tggacttcgt tggttggtaa caatcgctcg
    31141 tcttcgtggt gaacacacaa tgcaagaccg tcttgcaaaa gaaatcttgg atgctgctaa
    31201 caacactggt gcagctgtta agaaacgtga agatactcac cgtatggctg aagctaaccg
    31261 tgcattcgca cacttccgtt ggtaagatag gatgcgaaag cgttaagaaa gtcccagaga
    31321 aaatagggaa tcgaagcagg ttgcggttgc aaccaatgag attcatcttt ttctccagac
    31381 ttttagcttg agctcaacta aatcatgatg ctaggcacgg taaggatgca aggtgaaaat
    31441 aggaaactga cgcagtattc aacgaataca aggagtttta tctttttcac gcagcatccc
    31501 gttccagctc acatcggcta actaacttta gcccgggttc aaattagcta aatcgattag
    31561 tattagctat aactcagctt accatctcgt aagttgaaac caacaatagc atgaaaacat
    31621 tgagaacggg taggtcctgc ctatccgttt ttattaaaat cgtgttataa tagaatagaa
    31681 atcaaaaata aataggagaa acaaacctca tggcacgcga attttcactt gaaaaaactc
    31741 gtaatatcgg tatcatggct cacgtcgatg ccggtaaaac aacaactact gagcgtattc
    31801 tttactacac tggtaaaatc cacaaaatcg gtgaaactca cgaaggtgcg tcacaaatgg
    31861 actggatgga gcaagagcaa gaacgtggta tcacgatcac atctgctgcg acaacagctc
    31921 aatggaacaa ccaccgcgta aacatcatcg acacaccagg acacgtggac ttcacaatcg
    31981 aagtacaacg ttctcttcgt gtattggatg gtgcggttac cgttcttgac tcacaatcag
    32041 gtgttgaacc tcaaactgaa acagtttggc gtcaagcaac tgagtacgga gttccacgta
    32101 tcgtatttgc caacaaaatg gacaaaatcg gtgctgactt cctttactct gtaagcacac
    32161 ttcacgatcg tcttcaagca aatgcacacc caatccaatt gccaatcggt tctgaagatg
    32221 acttccgtgg tatcattgac ttgatcaaga tgaaagctga aatctatact aacgaccttg
    32281 gtacggatat ccttgaagaa gacatcccag ctgaatacct tgaccaagct caagaatacc
    32341 gtgaaaaatt gattgaagca gttgctgaaa ctgacgaaga attgatgatg aaatacctcg
    32401 aaggtgaaga aatcactaac gaagaattga aagctggtat ccgtaaagcg actatcaacg
    32461 ttgaattctt cccagtattg tgtggttcag ccttcaaaaa caaaggtgtt caattgatgc
    32521 ttgatgcggt tatcgactac cttccaagtc cacttgacat cccagcaatc aaaggtatta
    32581 acccagatac agacgctgaa gaaactcgtc cagcatctga cgaagagcca tttgcagctc
    32641 ttgccttcaa gatcatgact gacccattcg taggtcgttt gacattcttc cgtgtttact
    32701 caggtgttct tcaatcaggt tcatacgtat tgaatacttc taaaggtaaa cgtgaacgta
    32761 tcggacgtat ccttcaaatg cacgctaaca gccgtcaaga aatcgacact gtttactcag
    32821 gtgatatcgc tgctgccgtt ggtttgaaag atactacaac tggtgactca ttgacagatg
    32881 aaaaatctaa aatcatcctt gagtcaatca acgttccaga accagttatc caattgatgg
    32941 ttgagccaaa atctaaagct gaccaagaca agatgggtat cgcccttcaa aaattggctg
    33001 aagaagatcc aacattccgc gttgaaacaa acgttgaaac tggtgaaaca gttatctcag
    33061 gtatgggtga acttcacctt gacgtccttg ttgatcgtat gcgtcgtgag ttcaaagttg
    33121 aagcgaacgt aggtgcgcct caagtatctt accgtgaaac attccgcgct tctactcaag
    33181 cacgtggatt cttcaaacgt cagtctggtg gtaaaggtca attcggtgat gtgtggattg
    33241 aatttactcc aaacgaagaa ggtaaaggat tcgaattcga aaacgcaatc gtcggtggtg
    33301 tggttcctcg tgaatttatc ccagcggttg aaaaaggttt ggtagaatct atggctaacg
    33361 gtgttcttgc aggttaccca atggttgacg ttaaagctaa gctttatgat ggttcatatc
    33421 acgatgtcga ctcatctgaa actgccttca agattgcggc ttcactttcc cttaaagaag
    33481 ctgctaaatc agcacaacca gctatccttg aaccaatgat gcttgtaaca atcactgttc
    33541 cagaagaaaa ccttggtgat gttatgggtc acgtaactgc tcgtcgtgga cgtgtagatg
    33601 gtatggaagc acacggtaac agccaaatcg ttcgtgctta cgttccactt gctgaaatgt
    33661 tcggttacgc aacagttctt cgttctgcat ctcaaggacg tggtacattc atgatggtat
    33721 ttgaccacta cgaagatgta cctaagtcag tacaagaaga aattattaag aaaaataaag
    33781 gtgaagacta atccgtcctc actctagaag gaagtcactt agtggcttcc ttttgtcttt
    33841 agaaaatacc tctaaatatg gtaaaatagt agaagaataa tgtgaggaaa atgaatgtca
    33901 aatagttttg aaattttgat gaatcaattg gggatgcctg ctgaaatgag acaggctcct
    33961 gctttagcac aggccaatat tgagcgagtt gtggttcata aaattagtaa ggtatgggag
    34021 tttcatttcg tattttctaa tattttaccg attgaaatct ttttagaatt aaagaaaggt
    34081 ttgagcgaag aattttctaa gacaggcaat aaagctgttt ttgaaattaa ggctcggtct
    34141 caagaatttt caaatcagct cttgcagtcc tactataggg aggttttctc tgaaggtcca
    34201 tgtgctagtc aaggttttaa gtccctttat caaaatttgc aagttcgtgc tgagggtaat
    34261 cagctattta ttgaaggatc tgaagcgatt gataaggaac attttaagaa gaatcatctt
    34321 cctaatttag ccaaacaact tgaaaagttt ggttttccaa cttttaactg tcaagtcgag
    34381 aagaatgatg tcttgaccca agagcaggaa gaggcctttc atgctgaaaa tgagcagatt
    34441 gttcaagctg ccaatgagga agcgctccgt gctatggaac aactggagca gatggcacct
    34501 cctccagcgg aagagaaacc agtctttgat tttcaagcga aaaaagctgc agctaaaccc
    34561 aagctggata aggcggagat tactcctatg atcgaagtga cgacagagga aaatcgtctg
    34621 gtatttgaag gggttgtttt tgatgtggag caaaaagtga ctagaacagg tcgtgtttta
    34681 atcaacttta aaatgacgga ctatacttca agtttttcta tgcaaaagtg ggttaaaaac
    34741 gaggaagagg cccagaagtt tgacctcatc aagaagaatt cttggctccg agttcgaggg
    34801 aatgtggaga tgaataattt cacacgcgat ttgactatga acgtacagga tctgcaggaa
    34861 gttgttcact atgagcggaa ggatttgatg ccagaaggtg agcgtcgggt tgagtttcat
    34921 gctcatacta acatgtcgac tatggatgct ttgccagagg tcgaagagat tgttgcaaca
    34981 gctgctaagt ggggacacaa ggcggttgct atcacggacc atgggaatgt ccagtccttt
    35041 ccacatggct ataaggcggc taagaaagcg ggaatccagc tgatctatgg aatggaagcc
    35101 aatatcgtgg aggaccgtgt ccctatcgtc tataacgaag tggagatgga cttgtcagaa
    35161 gcaacctacg tggtctttga cgtggaaacg acgggacttt cagctatcta taatgacttg
    35221 attcaggttg cggcctctaa gatgtacaag gggaatgtta ttgctgaatt tgatgaattt
    35281 atcaatcctg ggcatccctt gtcagctttt actacagagt taactggaat tacagatgat
    35341 catgtcaaaa atgccaaacc actagaacaa gttttgcaag aattccaaga attttgcaag
    35401 gatacggtcc tagttgccca caatgctacc tttgacgttg gctttatgaa tgctaattat
    35461 gagcgtcatg gtcttccaaa gattagtcag ccagttattg atacgctgga gtttgctaga
    35521 aacctctatc ctgagtataa acgccatggt ttggggcctt tgaccaagcg ttttggtgtg
    35581 gccttggaac atcatcacat ggccaactac gatgcggaag cgactggtcg tctgcttttc
    35641 atctttatca aagaggtagc agaaaaacat ggtgtgaccg atttagctag actcaacatt
    35701 gatctaatca gtccagattc ttacaaaaaa gctcggatca agcatgcgac catctatgtc
    35761 aagaatcagg taggtctaaa aaatatcttt aagctggttt ccttgtctaa taccaagtat
    35821 tttgaaggag tgccacggat tccgagaacg gttctagatg cccatcgaga gggcttgatt
    35881 ttaggttcag cctgttcaga gggtgaagtt tttgacgtgg tcgtttctca aggtgtggat
    35941 gcggcggttg aggtggccaa gtattatgac tttatcgagg tcatgccacc ggctatctat
    36001 gcgcccttga ttgccaaaga gcaggtcaag gatatggagg aactccagac cattatcaag
    36061 agtttgatag aggttggaga tcgccttggc aagcctgttc tggctacggg aaatgttcac
    36121 tatatcgaac cggaagaaga gatttatcgt gaaattatcg tccgtagttt gggacagggt
    36181 gcgatgatta accgaactat cggtcatggt gaacatgccc aaccagcacc acttccaaag
    36241 gctcattttc gaacgactaa tgagatgttg gatgaatttg cctttttggg agaggaactg
    36301 gctcgtaaac tggttattga aaacaccaat gccttggcag aaatatttga acccgttgaa
    36361 gtcgttaagg gtgacttgta tacgcctttc atcgacaagg ctgaagaaac agttgctgag
    36421 ttgacctata agaaagcttt tgagatttat ggaaatccgc tgccagatat tgttgatttg
    36481 cggattgaaa aagaattaac atccatactg gggaatggat ttgctgtgat ttatctggca
    36541 tcgcagatgc tggtgcaacg ttctaatgaa cggggttatt tggttggttc tcgtgggtct
    36601 gtcggatcta gtttcgttgc gaccatgatt gggattacgg aagtcaatcc tctctctcct
    36661 cactatgtct gtggtcagtg tcagtacagt gagtttatca cagatggttc gtacggttca
    36721 ggatttgata tgccccataa ggactgtcca aactgtggtc acaaactcag taaaaacgga
    36781 caggatattc cgtttgagac cttccttggt tttgatgggg ataaggttcc tgatattgac
    36841 ttgaacttct cgggagaaga tcagcctagc gcccacttgg atgtgcgtga tatctttggt
    36901 gaagaatatg ccttccgtgc gggaacggtt ggtacggtag ctgccaagac tgcctatgga
    36961 tttgtcaagg gttacgagcg agattatggt aagttttatc gtgatgcaga agtagaacgc
    37021 ctcgctcaag gagcggcggg tgtcaagcgg acaacaggcc aacacccggg gggaatcgtt
    37081 gttattccga actacatgga tgtctacgat tttacgcctg tccagtatcc agcagatgat
    37141 gtcacggctg aatggcagac cactcacttt aacttccacg atatcgatga gaacgtcctc
    37201 aaactcgatg tactgggaca tgatgatccg accatgattc gaaaacttca ggatttgtct
    37261 ggtattgacc ctaataaaat tcctatggat gacgaaggcg tgatggcact cttttctggg
    37321 actgatgtgc taggggtaac acctgaacaa attggaacgc ctacgggtat gttggggatt
    37381 ccagagtttg gaacaaattt cgtacgtgga atggtagacg aaacccatcc gacaaccttt
    37441 gcggaattgc ttcagctgtc tggtctgtcc cacggtactg acgtttggtt ggggaatgct
    37501 caggatctga ttaagcaagg aatagcggac ctatcgactg ttatcggttg tcgggacgac
    37561 atcatggttt acctcatgca tgcgggtctg gaacctaaga tggcctttac cattatggaa
    37621 cgggtacgta agggtttgtg gctaaagatt tcagaagagg agagaaatgg ctatatcgaa
    37681 gcaatgaagg ctaataaggt gccagagtgg tatatcgaat cctgtgggaa aattaagtac
    37741 atgttcccta aggcccatgc ggcagcctac gttatgatgg ccttgcgtgt agcttacttc
    37801 aaggttcacc atcctattta ttactactgt gcttacttct ccattcgtgc taaggctttt
    37861 gatatcaaga ccatgggtgc gggcttggag gtcatcaagc gcagaatgga agaaatctct
    37921 gaaaaacgga agaacaatga agcctctaat gtggaaatcg atctctatac aactcttgag
    37981 attgtcaatg agatgtggga acgaggtttc aagtttggta aattagatct ctactgtagt
    38041 caggcgacag agttcctcat cgacggggat acccttatcc caccatttgt agcaatggat
    38101 ggtctgggag agaacgttgc caagcaactg gtgcgggcgc gtgaagaggg agaatttctc
    38161 tctaaaacag aactacgcaa gcgtggtgga ctctcatcaa ccttggttga aaagatggat
    38221 gagatgggta ttcttggaaa tatgccagag gataaccagt tgagtttgtt tgatgagttg
    38281 ttttaaaaaa ttgcttaata atctattaaa agaggctaac gtatatccaa tagatttaca
    38341 ttagctttct tttttgttaa aatagtctat ggaaagaggg tgagagtatg tcaaagatga
    38401 gtataagcat ccgtctggat agtgaggtta aggagcaggc ccaacaggtg tttagtaatc
    38461 tgggaatgga tatgacaaca gctattaata ttttccttcg tcaggcaatt caatatcagg
    38521 gactaccttt tgatgttaga ctagacgaaa atcggaagtt gctccaagcg ttaacggatt
    38581 tagaccaaaa tcgtaatatg agccagtctt ttgaatcagt ctcagatttg atggaggact
    38641 tacgtgctta agattcgtta tcataaacag tttaaaaaag attttaagtt ggctatgaag
    38701 cgtggtttga aggcagaatt attagaagaa gttttgaatt ttctggttca agaaaaagaa
    38761 catcctgcca gatatcgtga tcattcattg acggcatcca agcattttca aggagttcgt
    38821 gaatgccata cccagccaga ttggcttttg gtttataaag tagacaagtc ggaattgatt
    38881 ttaaatttgc tgaggacagg cagtcacagt gatttatttt aatctatttt aagggggttc
    38941 tcatgaaact aagaatattt gcggaagata agccggctaa gaaggtattt gaatatcaat
    39001 tagaacttgc tgatcgtaca attcttctat cgacagcact cttgtcaggt gctattgctt
    39061 tagcaggaat cttttctgct ttgagagaaa aataaaaata gaaaagagaa aacagaatgg
    39121 ttttaccaaa ttttaaagaa aatctagaaa aatatgcgaa attgttggtt gcgaacggaa
    39181 ttaacgtgca acctggtcac actttggctc tctctattga tgtggagcaa cgtgaattgg
    39241 cacatctaat cgtgaaagaa gcttatgcct tgggtgcgca tgaggtcatc gttcagtgga
    39301 cagatgatgt gattaaccgt gagaaattcc tccatgcccc gatggagcgt ttggacaatg
    39361 tgccagaata caagattgct gagatgaact atctcttgga gaataaggct agccgtcttg
    39421 gagttcgttc atctgatcca ggtgccttga acggagtgga cgctgacaag ctttcagctt
    39481 ctgctaaagc tatgggactt gccatgaagc ctatgcgtat cgcaactcaa tctaacaagg
    39541 ttagctggac tgtagcagct gcagcaggac ttgagtgggc taagaaagtc ttcccaaatg
    39601 ctgcgagcga cgaagaagca gttgatttcc tttgggacca aattttcaaa acttgccgtg
    39661 tctacgaagc agatcctgtt aaggcctggg aagagcatgc agctatcttg aagagcaagg
    39721 ccgatatgct taataaggag caattttcag cccttcacta cacagcgcca ggaacagatt
    39781 taacacttgg tttgccaaag aaccatgttt gggaatcagc tggtgctgtc aatgcacagg
    39841 gcgaaggatt cttgccaaat atgccgacag aagaggtctt cacagcacct gacttccgtc
    39901 gtgcagatgg ttatgtcact tctacaaaac cgcttagcta caacggaaat attattgaag
    39961 gcattaaggt gacctttaag gatggacaaa tcgtagatat cactgctgag aagggtgatc
    40021 aggttatgaa agaccttgtc tttgaaaatg cgggtgcgcg tgccttgggt gaatgtgcct
    40081 tggtaccaga tccaagtcca atttctcagt caggcattac cttctttaac acccttttcg
    40141 atgaaaatgc gtcaaaccac ttggctatcg gtgcagccta tgcgactagc gttgttgatg
    40201 gagcggagat gagcgaagag gagcttgaag ctgcagggct taaccgttca gatgttcacg
    40261 tagactttat gattggttct aaccaaatgg atatcgatgg tattcgtgag gatggaacgc
    40321 gggtacctct tttccgtaat gggaattggg caaattaagg agataatatg ttaggaagta
    40381 tgttcgttgg tctcctagtg ggatttttag caggtgctat gaccaatcgt ggagagcgaa
    40441 tgggatgttt tggaaaaatg tttctcggtt ggatcggagc ctttctaggt cacttgctct
    40501 ttggaacttg ggggccagtt ttatcaggaa cagctattat cccagctgtt ttaggtgcca
    40561 tgattgtctt agctattttt tggagacgag gaagttaatt tcctaaatct gatactcaat
    40621 gaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc tcaaagcact gctttgaggt
    40681 tgcagataga actgacgaag tcagtaacat atatgcggca aggcgacgtt gacgcggttt
    40741 gaagagattt ttgaagagta tgaaacgaaa aggaggttgg tcattgtact agcctccttt
    40801 tgatatgata taatagttct atgagattag ataaattttt agttgcctgt gcggtgggaa
    40861 gtcggactga ggtcaaaaac ttgctcaagg ctgggcgcgt gactgtaaat ggtaaaaaag
    40921 aaaaatcagc taaattgcag attgatgaaa aaatagatga gattcgcttt gatgggcaag
    40981 tgttggagta tgaagagttt gtctactaca tgatgaacaa gcccaaagga gttatctcag
    41041 cgactgagga tcccaagcac agaaccgttc tggacttgtt ggatgacttg gcgcggagta
    41101 aggaagtttt tccagtagga cgcttggata ttgacacgca tggtcttttg ctcttgacca
    41161 ataatggtca gctggctcat gttcttcttt ctcccaagcg tcatgtggac aagacttatc
    41221 aggctcaggt caagggaatt atgacccaag aagatgtgga gacatttatc aagggcattc
    41281 cgctcaaaga ctttacctgt cagcccgcta gactggagat tctttccaca gatgcagaaa
    41341 agaatcagag ccaaatccgt gtgaccattg cagaagggaa gtttcatcag atcaagcgta
    41401 tggtgggcta ctgtggcaag gaagtggtgg acttgcaacg attgactatg ggaactttag
    41461 tattagatga gaacctggaa cgaggggaat ggcgtcgctt gaccaaggaa gaattagaaa
    41521 ttctccgcgc taatattatt taatttagtt taatactcaa tgaaaatcaa agagcaaact
    41581 aggaaactag ccgcaggctg tacttgagta cggcaaggcg acgttgacgt ggtttgaaga
    41641 gattttcgaa gagtataaat tcgaaaaagg tgagggagaa tgtccttacc ttttatgttt
    41701 tttagttgct tcctttgtga aaagagttat aatagactgt agaataaaag gaggaatcta
    41761 tgaacgcgat tcaagaatca tttactgata aactatttgc caactatgaa gcaaatgtaa
    41821 aataccaagc gattgaaaat gctgccagcc acaacggaat ttttgcagct ctggaacgtc
    41881 gccaaagcca tgtagacaac acacctgttt tctcattgga tttaaccaag gacaaggtca
    41941 ctaaccagaa agcgtctggt cgttgctgga tgtttgcggc tctcaacacc ttccgccaca
    42001 aactcatctc gcaatacaaa ttggagaact ttgagttgtc acaagcccac actttcttct
    42061 gggataagta tgagaaatca aactggttct tggagcaagt cattgcgact tcagaccaag
    42121 aattgactag ccgcaaggtt agcttcttac tccaaacacc tcaacaagat ggtggtcaat
    42181 gggatatggt cgtttccctc tttgaaaaat acggtgtcgt gcctaagtca gtttatcctg
    42241 agtctgtttc atctagcagc agtcgtgagc taaatgcgat ccttaataaa ttgcttcgtc
    42301 aagatgctca aatcttgcgt gatttgcttg tttctggtgc agatcaagtg actgttcaaa
    42361 ctaagaaaga agacctcttg caagaaatct ttaactttct tgctatgtca ttaggacttc
    42421 caccacgcaa gtttgacttt gcttatcgcg ataaagataa caactacaaa agtgaaaaag
    42481 gaatcacacc acaagagttc tacaagaaat atgtcaatct tcctttagaa gactacgttt
    42541 ctgttatcaa tgctccaact gctgataaac cttacggaaa atcttacaca gttgagatgt
    42601 tggggaatgt ggttggtagc cgtgcagttc gctacatcaa cgttccaatg gagcgcttga
    42661 aagaattggc gattgcccaa atgcaagcag gtgagactgt ttggtttggt tctgatgtcg
    42721 gccagctcag caaccgtaag gctggcatcc ttgcgacaga tgtttatgac tttgaatcaa
    42781 gcatggacat taaacttact caagacaagg ctggacgttt ggactatagt gaaagcttga
    42841 tgacccacgc catggtcttg acaggtgttg acttggacga aaatggtaaa tcaaccaagt
    42901 ggaaggttga aaactcatgg ggagacaagg tcggtacaga tggttacttt gttgcctcag
    42961 acgcttggat ggacgaatac acataccaaa tcgttgttcg taaggaattg ctgacagcag
    43021 aagaacaagc tgcctatgga gcagaaccaa tcgtacttgc accatgggat ccaatgggag
    43081 ccttggctga ataaaagcat agaaaaaagg aatcagattt tagaacctgg ttccttttta
    43141 gttgcttgat tacatgatgt gaagaacatg tgccacaata cccactgcga agagggcaag
    43201 gataatagtg attggagata cttttttctt aagtaagtac atgcaaagta aagtaaggag
    43261 tagtcctgat aatccaggaa tcaacatatc caagttttgt tggaaagtag taactttttc
    43321 aggagtttga gacaatcctt gtcctacttg tgcgaatgct tcttggatac ctttagaccc
    43381 ttctggcaat ttatcccaat ggatataagc cttttcatct agttgaactt tagaaacatc
    43441 gaaagcaaat ttaatattta cccagcgttg aacaaggaca gcaagaatga acatcccaag
    43501 gatagaagct cctttagtga tatcttgaag gataccacca gacatatctt tagtgatttc
    43561 tgatccagcc ttgtatccaa tctcttgaac ataccacaag aatgacatac gaatcaagtt
    43621 ccatgcaaca aagaagagga gtggacccaa gatattgcca gtaagggcaa gtgaagcacc
    43681 gagagatcca aggattgggc gtactgtaaa ccagaatact gggtcaccga taccagcaag
    43741 aggtcccatc ataccgattt taaccccttg gatagcagcg tcatcgattt ccacaccgtt
    43801 agcacgttct tcttcaagcg caagagtaac ccccatgact ggagcagcta cgtatggatg
    43861 agtgttgaag aactcaaggt gacgctcaag agcagcgatt tgatcttctt ttttagtata
    43921 gagttttttg atagctggaa tgagtgtata agcccagccc aagttttgca tccgttcaaa
    43981 gttccaagac ccttgtaaga aggttgaacg ccaccaaact tttttacgat ctgatttagt
    44041 taattgaagt ttttcagtca tgatgttttc agtcctttct tatcttagta gtcttctagg
    44101 atatcgccga ttgggtcgtt agaagttgcg gctcctccgc caccatttcc accagtttta
    44161 gaaaggtgaa ggtagataag agcgatagca acaccgatag caccgaatcc gattagagta
    44221 atatctgaca cagcagcgag aacgaaacca agagcgaaga atggccatac ttcacgagtt
    44281 gccatcatgt tgataaccat ggcgtaacca acggcaacga ccataccacc accgatagcc
    44341 ataccatctt tgagccagtc tggcatggca ctaaggatac tttgtacagt ttcagttggt
    44401 accataagga gaagagctgc aggaagcgcg atacgaagtc cttggaaaag tagcgcaatg
    44461 aaatgcgcac gctccacagc gccgaagtca ccttttttag cggcagcatc tgcagtatga
    44521 accaaaccaa ctgaaattgt acgaacaatc attgtcaaga aaagtccagc tacggcaaga
    44581 gggatagcaa ccgcttgggc aacaccgata ccagtcttgg taaagtcacc accaagaacc
    44641 atgataatgg cagcagcgac agaagcaagt gcagcatcag gagcgatagc agcaccgata
    44701 tttgaccaac caagggcaat catttgaagc gatccaccga ggataatccc tgcttccaag
    44761 tgacctgtta caagcccaat aagggtacag gctacaagtg gttggtgaaa ttggaactgg
    44821 tcgaggatgc cttcaagacc tgcaaagaag gctacaacga ctactaaaac catagaaata
    44881 atagacatgt ttaaaatcct ttcataaata atggcttatt tgacattggc tttgttaatc
    44941 aagtcaaaca aatctttttt agaatcattt ggtactttac ggacatcaaa ttcaacaccc
    45001 aagtcacgca ttttttcaaa tgtagcaaca tcttctttgt ccatagacaa aacggtattg
    45061 accaatgttt tacctgttga gtgagccata gaaccaacgt taagagtctt gattggcacg
    45121 ccgccttcga tggcacgaag ggcatcttga ggtgtttcaa acaagataag ggcatgtgtt
    45181 tctccaaaac gtgggtcttt tgaaatctca atcagttttt gaattggaac cacgttagcc
    45241 ttgacattac ctggagctgc ttgtttaatc aattctttac gaaggtcgtc tttagccacg
    45301 ttatctgaag caacgatgat acgatttgct tttgaatctg gagtccaagc agttgcaacc
    45361 tgaccgtgaa gtagacgtgt gtcaagacgg gcaagattga ttttcaattt accgtctccg
    45421 ataacagttc cttctgggat agcagtttgg gcaactggag cagctgcagc gcttgcaact
    45481 tcttcaactg gatttagctc ttctggaaga gctttgatgc catctttggc ttctttaatg
    45541 atattagcag cgactttttc tacacctgca gcagcgtcca tgaggcgctc tgtgtaggct
    45601 tgaatcaaca tcggtaagtt aagtcctgtg atgatggcaa acttacgctc aggattttct
    45661 cccatcacgc gactagcttg gttaaatgga gaaccactcc aaaggtcagc caaaactaga
    45721 acctcatctt ctgcgtcaaa tgcagcaaca gcgttattaa acttagcgta tagatcatca
    45781 ggaccttcat ttggcataaa ggtcacaact tgaacctttt cttgttcacc aaagatcata
    45841 gatcctgact gatgaatacc cgcagcaaat tcgccgtggc tcgcaataat gattccgata
    45901 ctcattattg tcattcctcc ttttttgttt tagttttcat ttaagaaaac tttaagactg
    45961 tttaagtata aaccgttttc ataaaaaaag caactattta tcataaaaaa ttaaaaaatt
    46021 tttattttta tatgttgata tgttgagttt ttgaggagta atcttgaatt cttatttaaa
    46081 atttaatata aaaaagttgg aagaagcttc caacttttaa aataggtttc tattagatta
    46141 gtgggtgaag tcgagtacca tacgtccttg gatttggcct ttttccattt cgtcgaaaat
    46201 ggcaacagca tcttctactg gacgtttttg aacaactggg actaccagac cttctgcacc
    46261 aaattggaag gcttcttcta agtctttacg agttccgaca agagaaccga tgacttggat
    46321 tccatcgagg actgttttaa cgatgctgag ttccatcgtt tcagaaggaa gaccaacagc
    46381 gacgacgcga ccaccagcac gaatggagtc aacagcctgg ttgaaggcaa ctttagacac
    46441 agcagttacg acagctgaat gagctcctcc atcagttttt tctttaatga gtccagctac
    46501 atcttcaact tcgaggccgt taatcacaat gtcagcgcct acttcttttg caagggcaag
    46561 tttgtcattg ttgatatcga ctgcgataac atgagcattg aatacttttt tagcgtattg
    46621 aacagcgagg ttaccaagtc caccagcacc gtaaagaaca acccattggc ctggttcaac
    46681 ttttgcttct ttgatagctt tataggttgt tactccagca catgtgatag aagaagcttg
    46741 ggctggatca agtccgtcag gaactttgac agcatagtca gcagttacga tacattgttc
    46801 agccatacca ccgtctactg agtagccagc atttttcact gtacggcaaa gggtttcgcg
    46861 accagttgta cagtattcgc aagtgccaca tccttcaaag aaccaagcaa cgctgacgcg
    46921 gtcaccgact ttaaggcttt tcacatctgg agcaatctct ttaacgatac cgataccttc
    46981 gtgcccaaga acacgtcctg ggacttgacc aaagtcacca tgagcaacgt ggaggtcggt
    47041 gtggcaaacg ccacagtatt caacttctac aagtgcttcc ccagtttcaa gtggacggag
    47101 tactttttct tcaatagcaa caccagtgct ttctggattt acaacaacag ctttcatagc
    47161 tatcctcctt gatattgacc gagaacaggg acaacgggac tggattgatt ttttgtcaac
    47221 agagtcgagt gtgacgagct ctcttgtatt tatatgtgaa gtatatcaca aaagaaagcc
    47281 ttttccaagg ttttggagac aaaaagtaga acaatcgatt aactggttga tgagactgtg
    47341 aaaagagcac aaagaccagc ttgcaagctg gtcatactct tcgaaaatct cttcaaacca
    47401 cgtcagcttc atctacaacc tcaaagcagt gctttgagca acctacggct agcttcctag
    47461 tttgctcttt gattctcatt gagtatcagt ataggttata agaataagtc ttgtagggtt
    47521 ttggcaaccc catcttggtc gttggtaagg gaaatttgct catctgcata aggaagtagc
    47581 tctggattgg catttttcat ggcataaccc ttcccagcaa aagcgagcat ttcggtatca
    47641 ttgtgttcat ctccaaaggc aatcaaatct tttttgtcac gattcattat cttgagcaag
    47701 tagtccaaag caaaggcctt gttgacacct tttggggtac attcaaggat attgagcgga
    47761 cctccccagg tattgataga aagttgatgc tggtagaagg cgttcatgtc ttttgccaag
    47821 gcatatttgt cactggctct ggtctgcaag aggatacagt tagggtcctt ggtcaccaat
    47881 tcaggctgga attgatcttc aggctggaaa gcttctacac caaatagttt gggattggca
    47941 atctcttcat tgggatttgt aatgtagaat tttttacgat attctccagc gataaaatcg
    48001 gcttgaatgt cctctgaacg ttgaaccata tctagcagat attttttgtc tacagtcaaa
    48061 cacttttcaa aatcccaaac ttggtctggt aaatgagtaa gggatccgtt gaagttaatc
    48121 ataggagtgt ctaagcccag ttcacggtaa aaatcttttg acatacggta agggcgacct
    48181 gtcgtaataa taacctgatg gcctttttca gcaacttttt tgatggtttt tttggtaaag
    48241 tcagaaattt gactgtctga gttgagcagg gttccatcca ggtcaactgc aataattttt
    48301 ttcgtcatat ggacctttct agtgtgtttt cagataagat gtcttctatt ataacagaaa
    48361 gcaggcagaa aagcagattc caaacaaaaa atgaaattgg attaatttct taaacaaatc
    48421 aaacaaagac attgaaaaag tgaatgataa atgatataat tctattattg ttcgtaaaaa
    48481 ttaaaaggag attgatgatg gacaaattat ttaaactaaa agagaacggt acagacgttc
    48541 gtacagaggt tctcgctggt ttaacaactt tctttgcaat gagctatatt ctctttgtaa
    48601 acccacaaat actttcacaa acaggaatgc ctgctcaggg tgtcttccta gcgacgatta
    48661 ttggtgcagt agcgggtacc ttgatgatgg ctttttatgc taacttacct tatgcccaag
    48721 cgccaggtat gggactcaat gccttcttta cctttacagt tgtattcggg cttggttatt
    48781 cttggcaaga agccctagct atggtcttca tctgtgggat tatttcattg attattacct
    48841 tgacaaaggt tcgtaaaatg atcattgaat cgattcccaa tgctcttcgc tcagctattt
    48901 cagctggtat cggtgtcttc cttgcctatg tagggattaa gaatgctgga cttttgaaat
    48961 tcacgattga tccaggcaac tatactgttg taggagaagg ggctgacaaa gctcaagcaa
    49021 cgattgcagc aaactcttca gcagttccag gattggtcag ctttaataat ccagctgttt
    49081 tagtggctct tgcaggactt gccattacta tcttctttgt catcaaaggg attaaagggg
    49141 gaattattct ctctatcttg acaacaactg ttcttgctat tgcagttggt ttggttgatt
    49201 tgtctagtat cgattttgct aataaccatg ttggtgcagc ttttgaagat ttgaagacaa
    49261 tctttggtgc agctcttggt tcagaaggtt taggagcttt ggtttcagat acagctcgct
    49321 tgcctgaaac tctgatggcc attcttgcct tctcattgac agatattttt gacacaattg
    49381 gtaccttgat cggtacaggt gaaaaagttg gtattgtagc gacaaatggt gaaaatcacc
    49441 aatcagccaa attggataag gctctttact ctgatttgat tggaacgaca gtcggtgcca
    49501 ttgcaggtac ttcaaacgta acgacttatg ttgagtctgc tgctggtatc ggtgcaggtg
    49561 gacgtactgg tttgacagcc ttggttgtag ctatctgttt tgcgatttca agcttcttta
    49621 gcccacttct agcgatcgta ccaacagcgg ctacagctcc aatcttgatt atcgttggga
    49681 ttatgatgct tggtagcttg aaaaatatcc attgggatga tatgtctgaa gcagttcctg
    49741 ccttcttcac atctatcttt atgggattca gctactctat cactcaaggg attgcagttg
    49801 gtttcttgac ttacactttg actaagcttg ttaaaggtca agttaaagat gttcatgcca
    49861 tgatttggat tttggatgcc ttgtttatcc ttaactacat tagcatggcc ttataataga
    49921 atgacccagg gggatttccc ccctttttta atacaaagga gataggtgat gaaagagaaa
    49981 aatatgtgga aagaattgtt gaatcgtgca ggctggattt tggtcttttt acttgccgtc
    50041 cttttatatc aggttcccct agtggttacc tctattttga ctttaaaaga agtagccctg
    50101 ctacagtcag ggctgatggt tgctggcctt tcaattgtgg ttctggctct atttattatg
    50161 ggagctcgta aaaccaagtt agctagtttt aatttttctt tttttagagc taaagatttg
    50221 gcacgtttgg gtttgagtta tttagttatt gtcgggtcaa atatacttgg ttctatcttg
    50281 ttgcaactgt caaatgagac gacaacagct aaccagtctc agattaatga tatggttcaa
    50341 aatagttcgt tgatttccag tttcttcttg ctagccttgc ttgctccgat ttgtgaggaa
    50401 atcttgtgtc gtgggattgt tcctaaaaag attttccgag gcaaggagaa cttgggattt
    50461 gtagtcggta cgattgtgtt tgctttattg catcaaccaa gtaatttacc ttctttattg
    50521 atttatggag gtatgtcgac agttctatct tggacggcct acaagaccca acgtttggaa
    50581 atgtcgatct tgcttcacat gattgttaat gggattgctt tctgtttgtt ggctcttgtg
    50641 gtgattatga gtcggacatt aggaatttct gtttaaaagc ttttatgtag aaaccgacct
    50701 ctttctacta gggaaagatg aatgcaatcg tgtccatctt tttcttttta tggtaaaata
    50761 gaaaaataat aagatgaaaa gccttgaggg agtgaccgat atgtcaagta aagccaatca
    50821 tgcaaaaaca gctatttgcg gaattatcaa tgtaacccca gactcctttt cggacggtgg
    50881 tcaatttttt gctcttgagc aggcactcca gcaggctcgt aaattgatag cagaaggagc
    50941 cagtatgctc gatatcggcg gagaatcgac tcggccgggc agtagctatg ttgagataga
    51001 agaggaaatc cagcgtgttg ttccagtgat caaagcgatt cgcaaggaaa gtgatgtcct
    51061 catctctatt gatacttgga agagtcaagt agcagaggct gctttggctg ctggtgccga
    51121 tctagtcaat gatatcactg gtcttatggg tgatgagaaa atggctcatg tggtagctga
    51181 agcgagagcg caagtggtca tcatgtttaa cccagttatg gctcggcctc agcatcctag
    51241 ttcgcttatc ttccctcatt ttggttttgg tcaaaccttt acagaaaaag agttagcgga
    51301 ctttgaaaca ttgccaatcg aagaattgat ggaggctttc tttgaacgag cactagcgag
    51361 agcggcagaa gctggtattg caccagaaaa tatcctgttg gatccaggaa ttggctttgg
    51421 tctgaccaag aaagaaaatc tgcttctttt acgggacctg gataaactac atcagaaggg
    51481 ctatccaatc tttctcggag tgtcgcgcaa gcgatttgtc atcaatatcc tagaggagaa
    51541 tggttttgaa gtcaatcctg agacagagct tggtttccga aatcgggaca cggcttcggc
    51601 tcatgtaact agtatcgctg cgagacaggg tgtagaagtg gtgcgcgtgc atgacgtagc
    51661 tagtcacagg atggcagttg aaattgcctc tgccattcgt ctggctgatg aagcggaaaa
    51721 tttagattta aaacaatata aataagatga aagaaattga aaacaatcag tggattgcta
    51781 actaccggac ggatcaaccg cattttggct tggaacgaat ggtggaactg ttagctttgc
    51841 gtggcaatcc ccatctcaaa ctcaaggtcc tccatatcgg agggactaac ggcaagggct
    51901 cgactattgc ttttttgaaa aagatgctag aaaagctagg gttgagagtt ggcgtgttta
    51961 gctcgcccta tctcattcat tacacagacc agattagcat caatggggaa tcgatctcag
    52021 aagcgaggct agaagctctc atggcagact atcagtcttt gctggaggga gaagcggtcg
    52081 ccaatttaca gggcacaacc gagtttgaga ttatcacagc cctggcctat gactactttg
    52141 cctcagagca agtagatgtg gccatcatgg aagttggcat gggtggactt ttggatagta
    52201 ccaatgtctg tcagcccatt ttgacaggaa ttacaactat tggcttggat catgtggccc
    52261 tacttggtga caccttggag tccatagcag agcagaaggc aggtattatc aaacaaggga
    52321 tgcccttggt aacagggcgt attgctccag aagccttagc tgtgattgac cgcattgcgg
    52381 aagagaaaga tgcgccgaga cttgcctacg ggacagatta tcaggttcgt catcaagaaa
    52441 gtgtggtgac aggggaagtc tttgactata caagtgctgt cagacaaggt tgcttccaga
    52501 ctagcctgct tggtttgtac caaatagaga atgctgggat ggccatagct ttacttgata
    52561 ctttttgtca agaagatggt cgagagctag caagcaatga ctttcttggt caagccttgg
    52621 aagaaacaag ttggccaggg cgtttggaaa tcgtgtcaag agatcccttg atgattttgg
    52681 atggagccca caatccccat gctatcaagg ccttgttggt aaccttgcaa gaacgttttg
    52741 cggatcatca taaggaaatc ctcttcactt gtatcaaaac caaagccttg gaggatatgt
    52801 tggacttgct gggagccatg ccagataccg agcttactct aacacatttt gcggatagtc
    52861 gggcgacgga tgaaagcgtg ctgaaagagg cagctaaggc tagaaatctc agctaccaag
    52921 attggcatga ttttctagag cagaatttga cagataaaaa agaagagaaa caaacagtta
    52981 ggattgtcac aggttccttg tatttcttga gccaagtgag ggcctatctg atggagagga
    53041 agaacgagaa tggatacaca aaagattgaa gcagctgtaa aaatgattat cgaggctgta
    53101 ggagagaacg ctaatcgcga gggcttgcag gaaacacctg ctcgtgtagc ccgtatgtat
    53161 caagagattt tttcaggtct tggtcaaaca gcagaggaac atttgtcaaa atcctttgaa
    53221 attattgacg ataatatggt ggtagaaaag gatatctttt tccataccat gtgtgaacac
    53281 cacttcttgc cattttatgg tagagcgcac attgcctaca ttccagatgg tcgtgtggca
    53341 ggcttgtcta agctagcccg tacggttgaa gtttattcga aaaaaccaca aattcaagaa
    53401 cgtttgaata tcgaagtggc cgatgccttg atggactatc taggtgctaa aggagccttt
    53461 gttgtcattg aggcggaaca tatgtgtatg agtatgcgtg gtgttagaaa accaggcact
    53521 gcaaccttga cgacagtagc tcgtggtcta tttgaaacag ataaggatct ccgtgaccaa
    53581 gcttatcgtt taatggggct ataaaaagaa tccgcttcaa gcggattttt ctagaaagga
    53641 atcattatgg atcaactgca gattaaggat ttggaaatgt ttgcctatca tggtcttttt
    53701 cctagtgaga aagaattggg gcagaaattt gtcgtttcag ccatcctatc ctatgatatg
    53761 accaaggcag ctacagactt ggatttaaca gcctctgtcc attacggaga attgtgtcag
    53821 cagtggacga cttggtttca ggaaacgagt gaagatttga ttgaaacggt agcctataaa
    53881 ctggtggaac gtacctttga gtcttatcct cttgtccaag aaatgaagtt ggaactgaaa
    53941 aaaccttggg caccggtgca tttgtcacta gatacttgct cggtaaccat tcatcgccgc
    54001 aagcaacgag cctttatcgc cctaggaagc aatatgggag ataaacaagc aaacttgaag
    54061 caagccattg acaaactgcg agctcgtggc atccatattc tcaaagagtc cagtgtctta
    54121 gcgacggagc cttggggtgg agtggagcag gatagctttg ccaatcaagt ggttgaggtg
    54181 gaaacctggc taccagcaca agacttgtta gaaaccttgt tagccattga gtcagagctg
    54241 ggacgggtga gagaagtgca ttggggacct cgtttgattg atttggactt gctctttgtg
    54301 gaggaccaga tcctttatac agacgacctc atattgcctc atccttacat agcggaacgc
    54361 ctttttgtcc ttgagtcctt acaggaaatt gcgcctcatt ttatccatcc gatattaaaa
    54421 caaccgatcc gcaacttgta tgatgctttg aaaaaataga aaaactctag ttttcagtca
    54481 cttgcaactg aaggctagag tttttatact cttcgaaaat caaattcaaa ccacgtcagc
    54541 gtcgccttac cgtactcaag tacagcttgc ggttagcttc ctagtttgct ctttgatttt
    54601 cattgagtat taaaataggt cattttcttc tgggaggagg atagtttctc taccgtccat
    54661 gtctaaaacc agtactcttg ggggataacg agggtcgaaa ggatggttaa agtcaaaatc
    54721 aatggctgta gggaggtgtt gacttgaaaa gtggaaggta atctttcctt ggttattaag
    54781 caattgaaac tcgagttctt cttccaattc aaagacattt tttaagaaat gatcgatgat
    54841 ataccaaaaa gagtcaatga tgtcatcggg caagctggta acaatgccaa aactagcaga
    54901 ccgcatgtgg gtattggtaa aagccatatc tctgtcccct ttcttttccc ttatcataca
    54961 gcaaatagga ttaaaaatca agaaaaggtg attttttgaa aaggatttta actacaggga
    55021 aaaagaagga aaaaaattcc caaaaatcta ccgaagttaa taggtaaatt cccaaattaa
    55081 cttgattata taactttcag ttactttgag aagttaccga aaaatatttt tcatatctat
    55141 tgacttttag gggtaaaatt tggtatgatg gtaggcggta ttgtttaccc catttgaaag
    55201 gccccggaac cttccaaata cttttcgatg ggaaggaaca cccatcaccg taaacaaaaa
    55261 tcgaactata tataggagaa atcatgaaca aaacaacatt tatggctaaa ccaggccaag
    55321 ttgaacgtaa atggtacgta gttgacgcaa ctgatgtacc acttggacgt ctttctgcag
    55381 tagttgctag cgtacttcgc ggaaaaaaca aaccaacatt tacaccacac actgatacag
    55441 gtgacttcgt gattgttatc aatgctgaaa aagttaaatt gactggtaaa aaagcaactg
    55501 ataaaatcta ctacactcac tcaaaccacc caggtggatt gaaacaaatc tctgcaggtg
    55561 aacttcgttc taaaaatgca gtacgtttga ttgagaaatc agttaaaggt atgcttccac
    55621 acaatacact tggacgcgct caaggtatga agttgaaagt atttgttgga gctgagcaca
    55681 ctcacgctgc acaacaacca gaagttcttg acatttcaga acttatctaa ggaaaggaac
    55741 aataaagtat gtcacaagca caatatgcag gtactggacg tcgtaaaaac gctgttgcac
    55801 gcgttcgcct tgttccagga actggtaaaa tcactgttaa caaaaaagat gttgaagagt
    55861 acatcccaca cgctgacctt cgtcttgtca tcaaccaacc attcgcagtt acttcaactg
    55921 taggttcata cgacgttttc gttaacgttg taggtggtgg atacgctggt caatcaggag
    55981 ctatccgtca cggtatcgct cgtgcccttc ttcaagtaga cccagacttc cgcgattcat
    56041 tgaaacgcgc aggacttctt acacgtgact cacgtaaagt tgaacgtaag aaaccaggtc
    56101 ttaagaaagc tcgtaaagca tcacaattta gtaaacgtta attcgaaaga attactatac
    56161 ttatacagag cacctttcgg ggtgttcttt ttttatactt tcttactaaa ttggtgcaat
    56221 tgacacagtt gttgcgactt tagtcgctta caaatgtggc tgcaacctga caaggtcagt
    56281 tgcctcaaaa cgttaatcaa tacgattata tcaatgtttc aaagcactca aaagtttacc
    56341 ttatttttat agtaaggtga aataagaata ggacaaaccg aggataatca aatcgaattc
    56401 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctact
//
LOCUS       DAVLHM010000005        52208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLHM010000005 DAVLHM010000000
VERSION     DAVLHM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.005"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(391..2007)
                     /locus_tag="VXE45_000334"
     CDS             complement(391..2007)
                     /locus_tag="VXE45_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788437.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            complement(2017..2970)
                     /locus_tag="VXE45_000335"
     CDS             complement(2017..2970)
                     /locus_tag="VXE45_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0788438.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            complement(2963..4167)
                     /locus_tag="VXE45_000336"
                     /pseudo
     CDS             complement(2963..4167)
                     /locus_tag="VXE45_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            4404..4730
                     /locus_tag="VXE45_000337"
     CDS             4404..4730
                     /locus_tag="VXE45_000337"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788439.1"
                     /translation="MEKVDRDKLKIYIETHPDAYLTEIAAEFNCPPTTIHYALKAMGY
                     SLKKSRTYCEQDPEKVNRFLKELNHLSYLTPIYIYETGVKTYFYLEYDRALSRQLVSL
                     EEDIII"
     gene            4931..5011
                     /locus_tag="VXE45_000338"
     CDS             4931..5011
                     /locus_tag="VXE45_000338"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788440.1"
                     /translation="MLPLPTYSPEYNPIEKIWAYIKNISE"
     gene            5403..6709
                     /locus_tag="VXE45_000339"
                     /pseudo
     CDS             5403..6709
                     /locus_tag="VXE45_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294462.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(6749..7759)
                     /gene="tsaD"
                     /locus_tag="VXE45_000340"
     CDS             complement(6749..7759)
                     /gene="tsaD"
                     /locus_tag="VXE45_000340"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0788441.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHELPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(7749..8186)
                     /gene="rimI"
                     /locus_tag="VXE45_000341"
     CDS             complement(7749..8186)
                     /gene="rimI"
                     /locus_tag="VXE45_000341"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0788442.1"
                     /translation="MIEIKRIQQHPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(8183..8866)
                     /gene="tsaB"
                     /locus_tag="VXE45_000342"
     CDS             complement(8183..8866)
                     /gene="tsaB"
                     /locus_tag="VXE45_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0788443.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            9044..9229
                     /gene="cibA"
                     /locus_tag="VXE45_000343"
     CDS             9044..9229
                     /gene="cibA"
                     /locus_tag="VXE45_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0788444.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            9231..9383
                     /gene="cibB"
                     /locus_tag="VXE45_000344"
     CDS             9231..9383
                     /gene="cibB"
                     /locus_tag="VXE45_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0788445.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(9706..9921)
                     /locus_tag="VXE45_000345"
     CDS             complement(9706..9921)
                     /locus_tag="VXE45_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788446.1"
                     /translation="MYNLFAFAIGVRLLAFIVFVACVYGGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            10201..10434
                     /locus_tag="VXE45_000346"
     CDS             10201..10434
                     /locus_tag="VXE45_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0788447.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            10436..12115
                     /locus_tag="VXE45_000347"
     CDS             10436..12115
                     /locus_tag="VXE45_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0788448.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(12213..12290)
                     /locus_tag="VXE45_000348"
                     /pseudo
     CDS             complement(12213..12290)
                     /locus_tag="VXE45_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12494..14407)
                     /gene="mnmG"
                     /locus_tag="VXE45_000349"
     CDS             complement(12494..14407)
                     /gene="mnmG"
                     /locus_tag="VXE45_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0788449.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(14417..14872)
                     /locus_tag="VXE45_000350"
     CDS             complement(14417..14872)
                     /locus_tag="VXE45_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0788450.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(15013..16134)
                     /gene="mnmA"
                     /locus_tag="VXE45_000351"
     CDS             complement(15013..16134)
                     /gene="mnmA"
                     /locus_tag="VXE45_000351"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0788451.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTNLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(16534..18699)
                     /gene="pspA"
                     /locus_tag="VXE45_000352"
     CDS             complement(16534..18699)
                     /gene="pspA"
                     /locus_tag="VXE45_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV0788452.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTLVRAEEAPVANQSKAEK
                     DYDAAVKKSEAAKKDYETAKKKAEDAQKKYDEDQKKTEEKAELVRKADEKRQKANLAV
                     QEAYVKFQEAQREFNESPSRKKSDAKKKLDDASAHIEEVKLKQKEADANFNKEQAKVI
                     PEASDLAVTKQKAEEAKKEAEVAKEKYDKAVQEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKGIAPYQNKVAELNKEIARLQSDLKDAEENNVEDYIKEGLEQAIADKKAELAT
                     TQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKEAAEDANIEALQNKVADLEN
                     KVAELDKEVTRLQSDLKDAEENNVEDYVKEGLDKALTDKKVELNNTQKALDTAQKALD
                     TALNELGPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARR
                     SEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGW
                     LQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMAT
                     GWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAM
                     KASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            complement(18986..19489)
                     /locus_tag="VXE45_000353"
     CDS             complement(18986..19489)
                     /locus_tag="VXE45_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788453.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQDGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            complement(20621..21349)
                     /locus_tag="VXE45_000354"
     CDS             complement(20621..21349)
                     /locus_tag="VXE45_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788454.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            complement(21346..21699)
                     /locus_tag="VXE45_000355"
     CDS             complement(21346..21699)
                     /locus_tag="VXE45_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0788455.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            complement(21755..22657)
                     /locus_tag="VXE45_000356"
     CDS             complement(21755..22657)
                     /locus_tag="VXE45_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788456.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(22865..23239)
                     /locus_tag="VXE45_000357"
     CDS             complement(22865..23239)
                     /locus_tag="VXE45_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV0788457.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(23616..24593)
                     /locus_tag="VXE45_000358"
     CDS             complement(23616..24593)
                     /locus_tag="VXE45_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788458.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            complement(24907..25965)
                     /locus_tag="VXE45_000359"
     CDS             complement(24907..25965)
                     /locus_tag="VXE45_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788459.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(26847..27059)
                     /locus_tag="VXE45_000360"
     CDS             complement(26847..27059)
                     /locus_tag="VXE45_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788460.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(27067..27438)
                     /locus_tag="VXE45_000361"
     CDS             complement(27067..27438)
                     /locus_tag="VXE45_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV0788461.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            28196..28516
                     /locus_tag="VXE45_000362"
     CDS             28196..28516
                     /locus_tag="VXE45_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0788462.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILFHLKKEVEIYYQ
                     AKER"
     gene            complement(28805..29275)
                     /locus_tag="VXE45_000363"
     CDS             complement(28805..29275)
                     /locus_tag="VXE45_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0788463.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(29241..30047)
                     /locus_tag="VXE45_000364"
     CDS             complement(29241..30047)
                     /locus_tag="VXE45_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0788464.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(30263..30904)
                     /locus_tag="VXE45_000365"
     CDS             complement(30263..30904)
                     /locus_tag="VXE45_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788465.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(30901..33009)
                     /locus_tag="VXE45_000366"
     CDS             complement(30901..33009)
                     /locus_tag="VXE45_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0788466.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(33061..33348)
                     /locus_tag="VXE45_000367"
     CDS             complement(33061..33348)
                     /locus_tag="VXE45_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0788467.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            33773..34093
                     /locus_tag="VXE45_000368"
     CDS             33773..34093
                     /locus_tag="VXE45_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0788468.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(34146..34718)
                     /locus_tag="VXE45_000369"
     CDS             complement(34146..34718)
                     /locus_tag="VXE45_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0788469.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            34960..35631
                     /gene="sdaAB"
                     /locus_tag="VXE45_000370"
     CDS             34960..35631
                     /gene="sdaAB"
                     /locus_tag="VXE45_000370"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0788470.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            35640..36512
                     /gene="sdaAA"
                     /locus_tag="VXE45_000371"
     CDS             35640..36512
                     /gene="sdaAA"
                     /locus_tag="VXE45_000371"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0788471.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            36534..37166
                     /locus_tag="VXE45_000372"
     CDS             36534..37166
                     /locus_tag="VXE45_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0788472.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            37216..37293
                     /locus_tag="VXE45_000373"
                     /pseudo
     CDS             37216..37293
                     /locus_tag="VXE45_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(37559..39409)
                     /locus_tag="VXE45_000374"
     CDS             complement(37559..39409)
                     /locus_tag="VXE45_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0788473.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(39451..40608)
                     /locus_tag="VXE45_000375"
     CDS             complement(39451..40608)
                     /locus_tag="VXE45_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0788474.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            40666..41832
                     /locus_tag="VXE45_000376"
     CDS             40666..41832
                     /locus_tag="VXE45_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0788475.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            41971..42297
                     /locus_tag="VXE45_000377"
     CDS             41971..42297
                     /locus_tag="VXE45_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0788476.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            42284..42877
                     /locus_tag="VXE45_000378"
     CDS             42284..42877
                     /locus_tag="VXE45_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0788477.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            42870..43781
                     /locus_tag="VXE45_000379"
     CDS             42870..43781
                     /locus_tag="VXE45_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0788478.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            43844..44908
                     /locus_tag="VXE45_000380"
     CDS             43844..44908
                     /locus_tag="VXE45_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788479.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(45086..45946)
                     /locus_tag="VXE45_000381"
     CDS             complement(45086..45946)
                     /locus_tag="VXE45_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0788480.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFERVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(46221..47207)
                     /locus_tag="VXE45_000382"
     CDS             complement(46221..47207)
                     /locus_tag="VXE45_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0788481.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEREQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(47479..48954)
                     /locus_tag="VXE45_000383"
     CDS             complement(47479..48954)
                     /locus_tag="VXE45_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0788482.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(49164..50087)
                     /locus_tag="VXE45_000384"
     CDS             complement(49164..50087)
                     /locus_tag="VXE45_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0788483.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(50101..51030)
                     /locus_tag="VXE45_000385"
     CDS             complement(50101..51030)
                     /locus_tag="VXE45_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0788484.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(51349..51569)
                     /locus_tag="VXE45_000386"
                     /pseudo
     CDS             complement(51349..51569)
                     /locus_tag="VXE45_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(51523..51783)
                     /locus_tag="VXE45_000387"
     CDS             complement(51523..51783)
                     /locus_tag="VXE45_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788485.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT        16064 a        11036 c         8840 g        16268 t
ORIGIN      
        1 ttgtacccgg gacactattt atgttatcaa gaacactatc ttgaaacctc aactcacagt
       61 tctttttgtg aaattctttt ttatcgttta gatttgatat ttttttagac atttcaacaa
      121 tctcagacat tttatatgga tatctaggat gaatgccaaa actatgcaaa atgaactgca
      181 ccccaaaagt tagacagaat aaatctaact tttggggtgc agttcataag attgggatat
      241 ttttttttag ctagaactag tagaaatata tagtcaaata acagatacct taagggtttc
      301 tcatctacat aaaaaaatga tacttttttc tcttcagtaa ttacctcata agcttcacaa
      361 tagaatctca tgtttccctc ccctatattc ttaaataaaa tcctttggaa attgatatat
      421 cttagtaaaa tattgtttaa gttccggatg cggagcatgg gtaacaataa tgacagtcaa
      481 atcctctcta tctaatatct tacgttcaat cgctaacgaa gttctcctat cgatagcaga
      541 agttccctcg tcaattaata ctattttctt atttctaatt aggcctctag ctaaagtaat
      601 tttttgtttc tgccctcctg acagtaatct cccatcatca ccaacataat aatctaaaat
      661 gttattagga aaatctttta cactcaaacc aacttgttct aaagactgta gtatttcttc
      721 atcagtataa ttttcttcca ataaaatatt atctctaatc gtaccttcaa acaaataagc
      781 tttttgatct acatatagaa cattcgaaac catatttaaa taggaggttt tttttatatc
      841 atccccgcag aatcgcaatt ctccactata atctctcaaa aagccattca ataattttaa
      901 taatgtagat ttcccgcttc cactttcacc taaaattaaa tacttttcat tacgttgaaa
      961 acaaaaattt aagtttttta atatttcttt atctccatac ttatagcaaa tattttttgc
     1021 ttcatataac ggaaaatctc tattcacctc atttggttcg atatcattca ttttatttga
     1081 ctcaattgga ttaattgaat acaattttaa aaaaataggc ttcgtaccaa taatagagga
     1141 taattgacct cctaattcac ctagcgctgt aaaaataaca cctgttagtg ctcctattgc
     1201 ttcaatagta ccaattttca ctattccttt tattgcaaga tagcctgtta aaaaaacgag
     1261 agatatctga aaaaaaatat tgagaaagaa gctaatagcg cctgctaacg tttctacagt
     1321 tgtctttctt tgtataacca tctttaataa aattcctgct tctttaattt tcttaggcaa
     1381 tacatataaa agattcaagg acgctaacac atcaaatcca ttcaatatag tctcactaga
     1441 ttttaaaaaa gcttcatttt ggctagttaa atttagacta acttctcgca ttttcgatgc
     1501 aaagattttt ggtacaagta gcataatcat taatgaaaac aaggtggcta cagtcaatga
     1561 ccaatgatag tgattaagag tcacaactgc aaatatagta ccagaaattc cttttattac
     1621 taaaaaaagt tgtttaaaag cctgatcatt taaagtctga acatcattat ttagccacga
     1681 aagatatgtt cctgatgatt tactatgaaa ttcttgatag gtagagttag agatgtctgt
     1741 ggcaactcta tttcgaatct ctagattaaa ctcttggatc acttcaacct gataattttt
     1801 cactacccag tcaaggaata ttatcccaca ccagacaatc atttggtaga ttgacaattt
     1861 caaaaaccgc tctaaattca tcgcaattaa ttcattcaac accagagcat taatagttgc
     1921 tgcataaatt agcaataatt gaccagcaac aataaatatc gttaataaac taaatttttt
     1981 tatatttgat tttataatag tatacacaat agtttctcac tttctaaatt ttaattgaac
     2041 atagttgtca tatatacaat agaaaaaacc aaaataatat aataacatgt atttcaaaaa
     2101 aagaaattcg ttaaaaattt tttcttctct tgccttcttg attactttta aagccttgca
     2161 tttgtctcct attaatagta accgctttat gtttaaagaa taatatttct ttgtaaccaa
     2221 tattctctcg ttgaaactca ataaattaaa atatttccta cagtaattat aatattcttc
     2281 atctgcatta attgtttttt gtgtcactcc agtgataccg ttttctttac tgtgagcgta
     2341 gtaattcacc aagaattctc gcactatatc aatttggtat ccttgagcaa gtagttttaa
     2401 taaaacaaca ccgtcctgat gtgaatctat tttctcaaaa ccattaatta attctagcac
     2461 ctctttttta cacaaccaaa atgacgtacc tgctatattg tgaaccattt gaacaaacaa
     2521 gggatttcca acaaaatcgg tcttctcctc ttctcgtgta ccatttggat aaattattat
     2581 tccataacta taaactaaag ctaaattctt cattctactc tttttaaaac aagccatcaa
     2641 ctttaaaatt cgatctggca tatattcatc atcatcgtct aaaaatgata tatacttacc
     2701 tctagaattt tttataccta tgtttctggc attagttgca cctaaatctt cattacttaa
     2761 aattaactta attctatgat ttgtatagcc aaattgatgg ataattttat ttcttaaatt
     2821 tacattacta taattatcat caataattat aacttcgata tttttataac tttgatgtaa
     2881 acaacttttc acagctctaa tcagagattc atacctatta tgtgttggta ttataatact
     2941 tactaattct tgatctatat tcctatccat gactactctt ctctaataat tcatcatata
     3001 ctctcatggt ttctacaaac attttttgca cagaaaaatg ttttcttatt tttgatttac
     3061 tattctcacc tatatatttc aaatactcag aatcattgag taaaaaatta gcacaagcac
     3121 acactccctc aacatcttcc ttctcaaata aaaatccatc aaccctatgt tcaataattt
     3181 cacttaaccc gccaacatta ctagctaaaa ccggagttcc ttgtgacatt gactctaaaa
     3241 cacacatagg tattccttct gtatcagaag gaatatacaa taaatccgat atttggtaaa
     3301 ctatagtagc tggatagatt tcaccaagta acctgaaatt atctctacat ttcaaatggc
     3361 aaattttttc tttcaaagca gcccacatac taccatttcc agccataata aaaatcacat
     3421 cttctctgac taaaaataat ttttctgcaa attcaaggaa tctatccggc cttttttctg
     3481 gatccaacct tccaatataa caaatgattt ttttgttatt tggaatacaa aattcttttt
     3541 taaagtcttg aacacctact acatctaaat cgctatttga tacattaatt ccgttattta
     3601 ttgcaattat cttcttattt tttattatac tctccaatct tttttcatag tttcagatac
     3661 acaaataaaa gcatctccca tagaatatgt ccaaaaatca aaataagtca agaatttctt
     3721 ttttaagtta tattcaaccc atccatggca tgttatcact gtcttaacct ttccaaatcc
     3781 attcttgtca agttttttta acatatataa aaaataatta gttgagtagc catgacagtg
     3841 tataagttgg atttttaata attttaaaat atttttaacg tgtaaggcag tttcaaaatt
     3901 atttgaacat tgagtacaat caacataggc aatatctaaa tttttataat catcaataac
     3961 ctttgaatct ctagatacga ttatcaaaat aggatataga gacatccttc tgatctgctt
     4021 tttacaaagt ccaattatat gcggatctat acctccacaa tgtccattat tatacctaac
     4081 tataatatga gccgaaaaca ctatatcctt aatgtctcca tatccatcag ggatattaat
     4141 atttattttt ccacaactat attgcattgt aaccatctcc ttaaacgacg cattatgata
     4201 tttgatagag aaatttttat gaataactca ataattttat agtaaatcat gcttatatct
     4261 caaagatacc tattttctct tgtctcgacc ttctccaaag aattgctata atactattac
     4321 aaatacatct gcactacact tcaaatttta gcactgtata aaaacgtttc aatacactaa
     4381 cttcaagaaa acttccacta ttaattgaaa aagttgatag agataaatta aagatctata
     4441 ttgaaactca tcccgatgct tatttgactg aaatagctgc tgaattcaac tgtcctccaa
     4501 caactattca ttacgctcta aaggctatgg gatatagtct aaaaaagagc cgtacctact
     4561 gcgaacaaga cccagaaaaa gtaaatcggt tccttaaaga attgaatcac ttaagctacc
     4621 tgactcctat ttatatttat gagacagggg ttaagaccta tttttatctc gaatatgatc
     4681 gagccttgag caggcagtta gtctctctgg aagaagatat aattatttga attaagatcg
     4741 agacaacgca caccagagat tgcgatactg ttatagaagt actaatgccc ttttttgttt
     4801 caatatacta tggctccttc gaagcttgct tccaaaaatt cttactacct actttagata
     4861 caccatccct tatcattatg gacaatgcaa ggtttcacag aatgaacatg tgtaaggagc
     4921 agggcataga ctgttaccac ttcctaccta ttcacccgag tataatccca ttgagaaaat
     4981 atgggcttac atcaaaaaca tctcagaata atattgtcaa attacgatgc ttttcttgag
     5041 gcacttttgt cctattcttg tttcagccga ctatactccg ttattgggca gctacggaac
     5101 agtcgatggg acgatggggg gacataaaaa aatcctccag ttttgttttt tataacagta
     5161 tactggagaa ttgacaatct cggtagatac ctcgttatag cgcggttact tattaggcag
     5221 ttacaaaaca actgtgaaca gaaaacattc cagagtcaga caagactttg gaatgctttg
     5281 gctctataat ttctgtagtg ggtaatccca ccccaggaat tatagggtcg tttcttgtag
     5341 aaaaaaagcc ccatatgacc tataatgaaa agcgtctaac caactcatta gaaagggttc
     5401 atatggaaca acttaagaat accacagatt tgctcggatt ggaagacaaa aatatcaaaa
     5461 tcttgtctgt tctgaaatac caaacccatc tagtcgttca ggcaaagttg gattcccccg
     5521 ctcctccttg tcctcattgt caagggaaga tgatcaaata cgacttccag aaaacctcta
     5581 aaattccgct tctcgactgt cagggtttac ccacggtact gcatctcaaa aagcgccgct
     5641 ttcagtgcaa gaattgcctt aaggtggtcg tttctcaaac atccattgtc aagaaaaatt
     5701 gccagatttc caacatggtg agacaaaaaa tcgctcagct cctccttgaa aagcagtcta
     5761 tgactgagat tgcccacaga ttggcggtct caacttccac cgtcatccga aaactgaggg
     5821 aatttaagtt tgaaaccgat tggaccaagt tgccaaaagt tatgagttgg gatgagtata
     5881 gcttcaaaaa gagcaaaatg agcttcattg cccaagattt tgagtccaaa tccatcctcg
     5941 caattttaga cgggcgaact catgcggtga ttcgaaacca tttccaacgc tatcagagag
     6001 aggttcggga gctggtcgag gtcatcacca tggacatgta cagcccttat tatcggctcg
     6061 ctaagcaact ctttccaaag gcgaagattg ttcttgaccg cttccacatt gtccaacatc
     6121 tgagccgagc tatgaaccga gtacgaatcc aaatcatgaa ccaatttgac cgaaaatcct
     6181 tggagtatcg ggcgctcaag cgcttttgga accctcgctt tttcgtttct aggctcgggc
     6241 taaatcagtc cactggactg atttactaca ccaggatagc ttcaagctct gtcagaaacg
     6301 attctatcag cccacgtttc gaatgcactt aacccatcgg gaagtacgag ataagctgct
     6361 ttcttactct gagggattac aggtttacta cgaactctat caactcctgc tctttcattt
     6421 tcaagagaag aatgccgacc atttctttgg attgattgag caagaactgc caacggttca
     6481 tccgcttttt caaacggtct tttggacttt tttaagggat agagataaga ttatcaacgc
     6541 acttaagctg ccttattcca acgctaaact tgaagcgacc aataatttga ttaaggttat
     6601 caagcgcaaa gcctttggtt tccggaactt taacaatttt aaaaaacgga ttttgatgac
     6661 tttgaacatc aaaaaagaga gtacgaattt cgtactctcc agattgtagc ttttcgccta
     6721 cccactacac ttgacaaaga gccactcttt attccatggt atcaaaggca agacttggtt
     6781 tggcattgag gtccaagttt gcaaagtttt ctttgttcca ctcgctgacg ctggcatagg
     6841 caatcatacc tgcattgtct ccgcagagtc gcagaggggg gatgataacc ttgacatctg
     6901 tgatttcggc tgctaggcgt tctctgagac ctttattggc tgccacacca cctgccacaa
     6961 ctagggtttt aacaggatat ttctccaaag ccttcttggt ttttgccatg agaatgtcca
     7021 taactgctgc ttggaaggaa gcacacaaat cttctgtaga caggctttct cccttttgct
     7081 cggcattgtg atgaagattg ataaaggcag atttcaaacc tgagaaggag aactccagat
     7141 tatcttcctt aatcatggca cgggggaaat cataaatatc ctgcccctga tgagccagct
     7201 cgtcaatctc acgacctgca ggataggtca agcccatgac acgaccgacc ttgtcataag
     7261 cctccccaac tgcatcgtct cgtgtctccc caacaatctt gtaatcgcca gcctcagaaa
     7321 catagaccaa ctctgtgtgc ccaccactga ctaaaagggc tagcaaggga aactccaaag
     7381 gctccacact ctgagctgcc atgaggtgcc cagccatgtg attaacagga atcagtggaa
     7441 gttcgtgagc ccaagcaaag gccttggcag ctgacaaacc aactagcaag gctccgacca
     7501 agcctggtcc gtaggtaacc gcaacagctg tcacgtcctc ttcggtaatc cctgcttctg
     7561 ccaatgcctc ctcgatacag gctgtaatga cctcgacatg gtgacgactg gctacttcgg
     7621 gcactacgcc accaaaacgt ttgtgactct caatttgact agcaatgaca ttggacaaga
     7681 gctcatcgtc gtttttcaag acggcgacac tggtctcatc acaggatgtc tcaaatgcta
     7741 aaatatatct atccttcatc tatttctctc ttcatgataa tggcgtcctc gactgggtca
     7801 tggtagtagg cctttcgctc agcgataact gccatctttt ctttcttgta aaatgcttgc
     7861 gctcgttgat ttgactgtct gacttcgagg aaaatttcct tgtctgtcgg caattgagca
     7921 aacaaggctg acgcaattcc ctgaccctga taagctcctt tgacagcgat ttgcaggact
     7981 tctgcttcaa aaagattctc ctgcacagct agaaatccaa tcacttctgc cccatcataa
     8041 gccaatgcat accaagtctg gtcttgggac agatctgctt ggatttgctc cagagtccaa
     8101 ggactgacta ggtaaacagc tgccataaca gcgtagatgg cttgagctag gtcaggatgt
     8161 tgttgaattc gcttgatttc tatcataggc gtttaatgta ggactcacca gactcggtgt
     8221 gattcttgag ccagttttcc tcagcttcga cacgcttgag gtagttcggc acaaaatcat
     8281 gcaaggagtc tgcttccttg tcccaagcta aaagagcaag attggctgca ttgggcaatg
     8341 tttctttgta atcagtcctt ggcaagtgtt tttgaatctg ctcaacaaag gggccaactt
     8401 ctccgacaaa ggttacctga ctagtaccct tgactttttc tagcacctct tcaaaagata
     8461 ggtgcgcttc tgccatgaca ggtttggcat tttcataaaa tcctgcataa acattattgc
     8521 gacgcgcatc catcaagggg acaaacaaac cttcttgttg gtggggcacc agagccaaga
     8581 gactcgacat accaaccaac tcgatgttca gggtgtaagc taaggtctta gcagttgcta
     8641 ccgcaattcg caagcctgta tagctacccg gcccttcagc taccacgatt cggtccaaat
     8701 ccttgggtgt ccaatccaaa cttgccatca aaaaatcgat ggcaggcata agagtaatac
     8761 tgtgattttt cttaatatta atcgtcgtct cggcaagaac ctgcttatcc tctaaaatag
     8821 ccagagaaag agccttgctg gacgtatcaa aagctaatac tttcataaca cattcctatc
     8881 tttttgtctg cttactatta tactacaaaa gctggcacat gggaattttc tttgccccca
     8941 gacaagagtg ccctcactta actaaaaata atttaaaaaa atgctcactt ttccttttct
     9001 tttccgaata taaaagtgaa caagaaaaaa ggaggaaagt tcaatgacaa attttgacat
     9061 tcttgacaat caatttttat ccttatctga aaatgaatta tcagatattg atggcggtct
     9121 cgctcccttg gttatctttg gagtagcagt atcttggaag gctattgcag gtggaacagc
     9181 acttataggt tctggtttgg cagctggtta ttttttagga ggagattaat atgatgaaag
     9241 atttgaacaa ttatcgtgaa atttctaata aggaattgca agaaatcaag ggtggctttg
     9301 gtgtcggtgt tggtatcgct ttatttatgg caggttatac cattggaaaa gaccttcgta
     9361 aaaagtttgg taagtcatgc tagataagaa acacattttt agaaggataa attttattgt
     9421 cttcatctct tacagtttgc tcagcattct caatgatttg aacattacta ccatcccttt
     9481 accattcgat ttatctgttt gtattgtttt atttttatgc ttcaactcta tttttgatca
     9541 gaacaatgac tcccataaaa ataataagct ttgaaaattc cattgtcatg tcatgttaga
     9601 aaaatgcaaa gaccacctca tcttgataga tggggtggaa ttttcgtgtc gtaaatctac
     9661 tatctctaca tccccaaaca aaaaacccca gcataagcag ggcatctaag catttaattc
     9721 aaagtaaaat acaaaccaaa cgacataggt cacgaggagg agaaaaagcg agtagagagt
     9781 cacaaaggtc attttccaca agaacttggt ttgtcgtcgt tccagtttgg caaatagaag
     9841 atttcctcca taaacgcaag caacaaaaac gataaaagct agcaaacgaa ctccgatagc
     9901 aaaagcaaat aagttataca tagggcaacc tccttgactt aaaatctata tggaattatg
     9961 acaagcaata aatttcactt ccgttatcaa cataatacat tttctttatt tttgcaaacg
    10021 cttaccaaag aaatcgtccc ctaactttct cgtttccgtc ttttactaat ttttcatttt
    10081 gtggtataat tgaaataatt gtaacgaatc aaggtcaatc tagacacaaa atggaatgaa
    10141 atcaagcaaa tctctgctaa aagtttggaa taagctgacc tgtaaataga aaggaactat
    10201 atgatttaca aagtttttta tcaagaaaca aaagaacgta gcccacgccg tgaaacaaca
    10261 cgcgcgcttt acctagacat cgatgccagc tcagaacttg agggccgtat cactgctcgc
    10321 caacttgtcg aagaaaatcg cccagagtac aatatcgaat atatcgaact cttgtctgac
    10381 aaattgctcg attacgaaaa agaaactggc gccttcgaaa ttacggagtt ctaatatggc
    10441 ctacactctt aaacctgaag aagtcggcgt ttttgccatc ggtggtctag gagaaatcgg
    10501 gaaaaacact tacggaattg aataccaaga cgagattatc atcgtcgatg ctgggattaa
    10561 attcccagaa gatgacttgc ttggtatcga ctatgtcatt cctgactact cttacatcgt
    10621 ggacaatatc gaccgcgtca aggctgtttt aatcacacac ggacacgagg accacattgg
    10681 tgggattccg ttcctactca agcaagcaaa tgtccctatc tacgctggac cgcttgcctt
    10741 ggctttgatc cgtgggaaac tcgaagaaca cggcctcttg cgcaacgcca aactttacga
    10801 aatcaaccac aacaccgagt tgacctttaa aaatctcaag gcaactttct ttagaacgac
    10861 tcactctatt ccagagcctt tggggattgt cattcatact cctcaaggga aaatcgtctg
    10921 tacgggtgac tttaagttcg actttactcc agttggagaa cctgcggact tgcatcgtat
    10981 ggctgcgctt ggtgaagaag gcgtgctctg tctcctgtct gactcgacaa atgcggaagt
    11041 accaaccttt accaactctg aaaaagtcgt tggtcagtcc attatgaaga ttatccaagg
    11101 tattgaagga cgtatcatct ttgcatcctt tgcctcaaat atcttccgtc tccagcaggc
    11161 aacagaagct gctgttaaga ctggacgcaa gattgcggtc tttggtcgtt ctatggaaaa
    11221 ggccattgtc aacggaatcg atcttggcta catcaaagct cctaagggaa cctttatcga
    11281 gccaaatgaa atcaaagatt atcctgcagg agaagttctt atcctctgta caggtagtca
    11341 gggtgagcct atggcagccc tctctcgtat cgccaacgga acccaccgtc aagtacaatt
    11401 acaaccaggt gataccgtta tcttctcttc tagtcccatc cctggaaaca ctactagcgt
    11461 caacaagctg attaacatca tttctgaagc tggtgtcgaa gttatccacg gtaaagtaaa
    11521 caatatccat acatctggac acggtggtca gcaagagcaa aaactcatgc tctgcttgat
    11581 taagccaaaa tacttcatgc ctgtccacgg tgaataccgc atgcaaaaag tccacgctgg
    11641 actagcagtg gatactggtg ttgagaagga caatatcttt atcatgagca atggcgatgt
    11701 gcttgccctt actgctgact cagctcgtat cgcaggtcat ttcaacgccc aagatatcta
    11761 tgtcgatgga aatcgtatcg gtgaaattgg cgcagctgtc ctcaaagatc gtcgcgatct
    11821 atctgaagac ggtgtcgttc tggcagtcgc aactgttgac ttcaaatcgc agatgattct
    11881 atctggtcca gacatcctca gccgaggctt tgtctacatg agagagtctg gcgacttgat
    11941 tcgccaaagc cagcgtatcc tcttcaatgc cattcgtatc gcactgaaaa ataaggatgc
    12001 tagcgtgcaa tctgtcaatg gtgccattgt caacgctatt cgccccttcc tctatgaaaa
    12061 taccgaacgt gaaccgatca tcatcccgat gatcctcaca ccagatgaag aataatactc
    12121 ttcaaaccac gtcagcttcg ccttgccgta tatatgttac tgacttcgtc agttctatcc
    12181 acaacctcaa aactgtgttt tgagctgact tcgtcagttc tatccacaac ctcaaagcag
    12241 tgctttgagc aacctacggc tagcttccta gtttgctctt tgattttcat tgagtacaaa
    12301 tcaacaaaac agccccgtct tcggagctgt ttttctctat gctttctttt gagattaaaa
    12361 ctcaatgaaa atcagactag aaggctaagc gaaagcataa cttgagttag ctcccatagt
    12421 tcggggaact atgggaggtt ggagatgaat caaagccaag ctttgaactc attcgtaaga
    12481 agccgacgac gtatcatttt gatttttgaa gagttttaga aatactacga tttttacctt
    12541 ccagatacac catcaaaata gaaatatctg ctgggtttac tcccgaaata cggctggctt
    12601 ggccgatggt ttctggattg atgagtttga acttctgacg agcttccgtc gcaatagaat
    12661 cgatgtcatc ccagtcgata ttggctggaa tgcgtttttc ttccatacgt ttcatcttgg
    12721 caacctgatc catggctttg gaaatatagc cttcgtactt gatttctgtt tcaatcaatt
    12781 cgataatctt gtcatccaag tcttctgcag ctggtccgat gaaggccacc acatcttggt
    12841 aagaaacttc tggacggcga aggaattctt tggctgtcac cgcatctgtc aacggcttga
    12901 agcccatttc ctcaacctta gcattggttt ccttgactgg cttgagtttg atactgtcta
    12961 ggcgtttcat ctcattatca aattgatttt tcttgatttc aaaacgagcc cagcgttcat
    13021 catccacaag gccaatctcg cgtcccatct cagtcaagcg catatcagca ttgtcatgac
    13081 gaagaatgag acggtattca gcacgacttg tcaagagacg gtagggttca atggttccct
    13141 tggtcaccaa gtcgtcgatc atcaccccga tataaccgtc actgcgcttc aaaatcaact
    13201 caggcttgcc ttggattttc agagccgcat tgatacccgc gataatccct tggccagcag
    13261 cttcttcata acctgatgtt ccatttgtct gaccagcagt gaagagacct gagattttct
    13321 tggtttccag agtcgcacgc aactgatgag gcaagaccat atcatactca atagcataac
    13381 ctgtccgcat catctctgca ttttccaaac ctttgatgga atgaaccaag tcacgctgga
    13441 catcctcagg cagactggtt gaaagtcctt gaacatagac ttcctcagta ttgcgccctt
    13501 ctggctcaag gaagagttgg tgacgttcct tgtccgcaaa gcgcacaatc ttgtcctcaa
    13561 tcgatggaca gtaacgaggc cccactccct tgaccacacc tgtaaacata ggcgcacggt
    13621 ggaggttgtt ttggataatc tcatgactgg taccattggt gtaggtcaac cagcatggca
    13681 cttggtcctt gacataatcc tcatcacgtg aagtgtatga gaagtgatta ggtgcttcat
    13741 ctcctggttg gatttctgtc acatcgtaat tgatagaaga agccttgaca cgtggagggg
    13801 ttcctgtctt gaaacgaccg atttcgaggc ccagttcctt gagattgtca gctaggttaa
    13861 tagaagccaa gctgtggtta ggacctgatg agtacttgag gtctccgatg ataatttccc
    13921 cacggagagc agtccctgtc gtcacaataa cagccttagc agcatattct tgatgggtgg
    13981 ctgtacgcac accgacaacc ttgccatctt ccaccaaaat ctcatcaatc atggtttgac
    14041 gaagggtcag attttcttgg ttttcaaccg tcttgcgcat ctccttagag taaagttcct
    14101 tgtcagcctg cgcacgaagg gcacggacag ctggcccctt ccctgtgttg agcatcttca
    14161 tctggatgta agtcttgtca atggttttgg ccatctcgcc accgagggca tcgacttcac
    14221 gcacgacaat ccccttggca gaaccaccga tagagggatt acaaggcatg aaagccagca
    14281 tttcaatatt gatggtcgca agcaggacct tacagcccat acggctagcg gccaaggaag
    14341 cctcaacccc agcgtgtccc gcaccaatta caataatatc gtattcttca gtaaaatgat
    14401 aagtcatgtt tctctcctat tcctcaagat gaatgtgtct tagttggcct tcccaatctg
    14461 gtagggctgt ttttaaaaag gctggaacta gctggatatc ctcaagctta tccaagtcaa
    14521 tccactcaca gggctgcctt ttctcatctt cctgcatggt caacggggca tcttcaagca
    14581 aatccaccag ataatgaaac tcgatattgt gataggaaac gccgtccact tcaaaacgat
    14641 tttcaaccac aaaagctagc tgcccagctt gagctttaac acctagttct tccttcactt
    14701 cacggactac cgcgtcttcc gttttttcgt taacttgaat cgcaccgccg atagtgtaat
    14761 acttgccctt gtctttggtg actagaagct tgtgattttg gacaatcaag gctgtcgccc
    14821 gaacaccaaa aaccgtattg tctacttttg tccgaaagtc ttgttgagtc attcttgtcc
    14881 tttcccttaa acgacacaaa aacagtcaaa actacaaaga agtgcaggac aaaaaagcct
    14941 gcaacatcca tgagctttga ccatcatttc tattgctgtt attattgtag caaattgaga
    15001 aaatttgtca atctaaatgt actgacaaac ttgtccatcg cggtaagcat tgtcaatcaa
    15061 accgccacct agacactctt cgccatcgta aaagacaact gcctgtcctg gtgtaatcgc
    15121 gcgttgtggt tccgcaaaga taacttctgc cttgtctcct ttgacatgga cggtcacctt
    15181 agagtcaggc tgacggtaac ggaatttagc cgtacattct agcgtaaact cttctggcat
    15241 ttcacgagta aagtggactt gactggcttc taggttagtt gacatgagcg aatcatggta
    15301 gaatccttgt cctacataga gaatattctt gcttagatct tttccgacaa cgaaccaagg
    15361 ggcattgtca ccgccgtgtt gcccaccgat accgagtccg ccacgctgac cgattgtata
    15421 gtacataaga cctgcatgct cgcccatatc gcgaccatcc acagtcatca tgcgaccagg
    15481 ctgagctggc aggtagttgc tgaggaagtt tttaaagttc ttttctccga taaaacaaat
    15541 ccctgtcgaa tctttcttct tagcagtcgc caggcctgct tcttctgcta gtctgcgtac
    15601 ttcaggcttt tccaaatgtc ccaaagggaa catggttttt tggagttgtt cttgcgaaag
    15661 ttggctgagg aaataggtct ggtccttgcc attgtccacg ccacgaagca tgtgaacagt
    15721 gccgtcctca tcacgcgcca ctcgagcata atgcccagtc gctacatagt ctgcccccaa
    15781 ggtcatggca tagtccaaaa aggccttgaa cttgatttcc ttgttgcaca taacgtccgg
    15841 atttggcgtg cgccctgcac ggtattccgc taggaaatac tcaaaaacgc ggtcccagta
    15901 ctctttttca aaattgacag agtagtaggg aatgccaatc tggtctgcca ccgcaaccac
    15961 atccttgtaa tcttcggtcg ccgtacaaac gccgttttca tctgtgtcat cccagttctt
    16021 catgaagata ccgatcacat cgtagccctg ctccttgagc aaaagagccg tcaccgacga
    16081 atcaacacca ccactcatcc ccacgacaac acgtgtttta gagttatcac tcatggtaag
    16141 tctccatcta ttcgtttatt cacgattgaa ggtcgtgtgt gcttcacgat tgaaggtcgc
    16201 ttgagcagta ttcattataa cacgcttggt tagagaagac aaggaagagc ttaaaaattg
    16261 ttttttaaaa cttatagtca atatacagat catgtgaatg acgtgagtat accctcttct
    16321 tatcttcatt caaataacta taataaataa aacaacccat tttctctaat ctatttttca
    16381 agttagagaa aaggagtcgt ttttttaatg acacttcctg aaatcataag ataggtacct
    16441 aaagaatacg aacataaatc tattcaatcg aaccttatct ttgtttcaaa attaaaatgt
    16501 caaatgttct taacatgatt taatttaatc ggcttaaacc cattcaccat tggcattgac
    16561 tttatagcca tctacagttg tgttgactgc aagggcacct aaaccattga catagtacca
    16621 tttatctgat actttgaacc attggcttgc tttcatagca cctgatgctt caagatagta
    16681 ccaggtatct ccatctttca cccaacctgt tgccattgaa ccgttagcgt tgaggtagta
    16741 ccatgaaccg ttgactttag cccaacctgt agccatagca ccgttagcgt tgaggtagta
    16801 ccatgaaccg ttgtattgga gccaacctgt agccatagca ccattagcgt tgaggtagta
    16861 ccatgaaccg ttgactttag cccaacctgt agccatagca ccgttagcgt tgaggtagta
    16921 ccatgaaccg ttgtattgga gccatcctgt agccatagcg ccgttagcgt ttaggtaata
    16981 ccatgaatcg ttgtattgga gccaacctgt agccatagca ccattagcgt tgaggtagta
    17041 ccatgaaccg ttgactttag cccaacctgt agccatagcg ccgttagcgt ttaggtaata
    17101 ccatgaacca ttgtattgga gccaacctgt agccatagcg ccattgctgt tgaggtaata
    17161 ccatgaaccg ttgttttgga gccaacctgt agccattgaa ccatcagtat tgtagaagta
    17221 ccacataccg ttttcttgtt tccaacctgt ttttggtgca ggaactggtt gctctggttt
    17281 tggtgctgga gctggttttt ctgcttttgg cggttgctgt tggggcaagc ggttatattc
    17341 ttcttctgat ctacgagcat agtcttcttc agcttgttga tcatctgttt tttctggttt
    17401 tggtgctgga gctggttgag gagccggcgc tggttttggt tgttcagctg gttgctctgg
    17461 ttttggtgct ggagctggag tttcttcttc atcaccgtca ggacctaatt cattaagagc
    17521 agtatctaat gctttttgag cagtatctaa tgctttttga gtattattta attcaacttt
    17581 tttatcagta agagctttat ctaagccttc tttaacgtag tcttctacat tgttttcttc
    17641 agcatctttt aaatcgcttt gaagtctagt aacttcttta tctaattcag caaccttgtt
    17701 ttctagatca gcaactttgt tttgaagagc ttcaatatta gcatcttctg cagcttcttt
    17761 atctaattca tcttgagttt taccttcagg gtctaatgta gctaatactt tttcaagttc
    17821 taattcagca tcctctaaat ctttttgagt tttatctatg ttttgttgag ttgtagctaa
    17881 ttcagctttt ttatcagcga tagcttgctc taaaccttct ttaatatagt cttctacatt
    17941 attttcttca gcatctttta aatcgctttg aagtctagca atttctttat ttaattcagc
    18001 gactttgttt tgataaggag caattccttt ttctaaatca gcgactttgt tttgaagtac
    18061 gtcaattttc ttttcgtttt cagcatcttg ttcaagtatt ttatttttct ctacttctac
    18121 ctcttgaact gccttatcat atttttcctt agctacttct gcttcttttt tagcttcttc
    18181 cgctttttgt ttagtaacag ctaagtcact tgcttcggga attacttttg cttgttcctt
    18241 attaaaattc gcatccgcct ctttttgttt taattttacc tcttcaatat gagctgatgc
    18301 atcatctaat ttctttttag catcagattt ttttctgctt ggactttcgt taaattctct
    18361 ttgtgcttct tggaatttta catatgcttc ttgaactgcc aaattcgctt tttgacgttt
    18421 ttcatccgct tttcgaacaa gctctgcttt ctcctcagtt ttcttctgat cctcatcata
    18481 tttcttctga gcgtcttctg ctttcttttt agccgtttcg taatctttct tagcagcttc
    18541 agattttttc actgctgcat catagtcttt ctcagcttta gactggttag ctacgggagc
    18601 ttcttctgct ctcaccaaag taggctgaga cgtaacaaaa ccagccccta agatagcgac
    18661 gctggctaga cttgttaaaa tcattttttt cttattcatc taaatttacc tcttttctga
    18721 tagtcatttt tagactatac ttatattaag tatactcccc ccgtaaatat ttgtcaaatg
    18781 ttttatatta catttttatt acaaatttct atatcataag cttctactcc aaaaagataa
    18841 agacactact tttgcccttt tcgattctct ttttaaacat agcatcatct tccttcattc
    18901 ctataaaaac atttccgatg agagagcttg tttttttaat ttcgttaaac aacaaaaaac
    18961 gcaagcttaa gcctgcggac aatctttata gccatttcat ttctttcaca tctgttttac
    19021 gaactttagc atatttctta gcgcttgtaa aatgtagggt aactggttta aatactccgc
    19081 ttttgtctct tcgtaaacct aaaactgcgg atcttttatt tttatcctca aaaaatatga
    19141 cgtccaattt catagtattt ttagataaat ccttagctac gatgcaacaa cttgttattt
    19201 tagaatagaa aatatcacct ataaactcat ataaagatat cctttcgatt acatcattgt
    19261 acaataggat atttctaaaa tcttctaaaa taaaaacacc atcttgaata gcaggttttg
    19321 tttgactagc ataatctcgt gtgattttgt gtaagccaaa taaatgatgt aaatcagtca
    19381 agcaaaaatt cactttgaaa gtctctaaat acttataatt cgttgatact tgacatgttt
    19441 ttccattgaa tctttcttga tagtccaaaa tacaatcaag taatttcaac gacaaactcc
    19501 atattttctc aaaataaaaa gcacggggca gttctcacta ctgcccaaag tggttgatta
    19561 gagtcggctt ctctaactcc ctatgttgtg cttattaggc ttatcgcaag ggaacagttt
    19621 ttagctctgc caagccacat aatgtgctta ctactatgtg tccatgtcac catgaattgc
    19681 cgaacggttt aacgagaaag tatagtagat tgaaacaaga tgtgaacaaa tcgattagga
    19741 aagtcaaatt aatttctaga aatattttaa cagtcataac ggactattcc agattcaatc
    19801 tactatatta cttttaggtt tatcccaact caattatgac atttttttca aaagtcaata
    19861 tatctcactc ttttcaacga caagaaagag gctgataatc gaccaacctc tgtttttaga
    19921 tacagttcaa gtccaaacta ttctttatag aaaagtccga taaattcgag caatagttaa
    19981 catacttaca aatataactc ccaaaataga taacactatt ttcacaaaac tcagttccga
    20041 acctatgaca tatatatgaa aaagaggggc tagtcctaca catatataca ataagtagcc
    20101 aacaagtttt atctcaccaa ttcctgcaaa aaaatgtttc atgtgacgat tctccattta
    20161 ctccattaaa tcagttttat tttagactat cataaaacaa tcacctcttc aataaaaacc
    20221 atttgcgaaa tactattctg aagcattgat agctcagatt tctcagaata gagctgtcct
    20281 aactatcgag cagctcaaat acatatatat gagcaattct aagcctagaa ttgctataaa
    20341 ataaatgttt ccaggctatt ctaagtcttt gactgcttaa aattttacat tctgaaggat
    20401 tctaaagcta gaacagctca aaatcacgag aactaaggta ttcgaaactt cagagtaata
    20461 caatccccat aggaattctc cattcttatt aagcatgatt aaaatgtaat cctaacaagt
    20521 gatcctcgac tgtgtttgta gcacttagtt acctagataa gactatttcc ctttatcata
    20581 tctgatttta agccgttcta agatttaacc tatgtttcta ttacttgcta tttttaaata
    20641 attcgtattc ctttgctttg ataaatggaa ctgaaaaatt agaaaaaaga agtaaaaccg
    20701 aaaacaaata gcctgctttt tgaatcacta aaagatatcc taaaaataag taagctataa
    20761 catccaatgc gaaaagaaaa aatattctcc tcttcattaa agtacttgtg tcaaataatc
    20821 tgatgaataa aaattttatc gtagtatcta cacaaatttt tatcaaaaag ataagagcca
    20881 atacacgatt atcaactgta ccgtaaagaa tagatggaaa tatagttaat ataaaactag
    20941 aaatctctaa atattttatc caaggagatt gagacacctt gcttctaaac tgactaattt
    21001 tcttatattc gttagtcaat ttagtagcaa aatcttcccc aattaaatga aagattgcta
    21061 actctaggat aaaaacactt attaatacgg tataagtcaa aaaactttct gggaaaaact
    21121 tattgattaa aatggggaaa ctcattaaca gaatcgaatt tatggctaga cagatagata
    21181 ctattttatt tttcacagaa tatagaggta gtgatactat tgagtagata aaagctaaaa
    21241 aaataagcaa aaaatactcc gtgtcattta taatcgccct gaatgataaa aatatataca
    21301 tccaacatac gataatatgt atttttcgaa tcttatctac attattcatc ttactgtcgc
    21361 agatatgaat ccatcccaag gataagggtt cccgctaata tcacaacctc tattaagagc
    21421 accatatcca atacagtaag ctatttttcc tgctgctgta gccaatacac ctgctgctgc
    21481 accaataagc cagcctccaa gacctccaaa cttaatatag tttattagtt ttttagttaa
    21541 aactgcagat ccagctaatg ctataaaagt tcctgggctc atagctaaag ctgcacaaat
    21601 tccttgacaa tcactcttgc ttaaataagc ccccccatca agatacatca tttcttcttc
    21661 atcaatcaca acataattat ttggtaatac aagttccatt tgttttctcc tccttagttg
    21721 aaattgtttc atttgtttta caaataggac gaacttaaac tatcttttta ttactcagta
    21781 ataatttccg agatttcatt ttatgatact ctctattcat acagaaatca aaattttgcc
    21841 ttaaccaact tgtataatag aaaaaatcta attgattgat tctgatgagg tgtatcctaa
    21901 ttttatcaac cttgttggac cagttgttat tgttactaat agaaatctca tacagcagta
    21961 actcgacaag acctgtacac agaagggtgt tatgagaatc ttcaatttta ctcagaatat
    22021 cctcaaagag ttcactatcc gttaaaaagg tagattgatt catcgcatca tacagctgaa
    22081 gagacattaa gtcagaataa ctgagatctg atttttgtat tttatccttt aacgtatttg
    22141 tcaaatcact ttcaaacgaa tcttcttttt cccatttatt ttgattgaaa agaaattccg
    22201 tcttattaaa aacgagatga ttgatatcca ttatagtcca gaaaaatatt gtagtaagca
    22261 tgatgattgc aaaaggaatt tttaaaataa atactaggat aatagcaatt tcaagaataa
    22321 aactccatat aatcctagat cttaaatcat caggcgacaa acttttacga tggaatgaaa
    22381 aatagggcga gaacctcaca tttactttct tcctgcctat aaaaataaaa ggaaaaatcg
    22441 taataagagc ttctttcttg tacaaatctt tcaatgcgta tagtatgtct aaaactattt
    22501 ttgataaaat caaactacag aaagcaagac tcatactaat cacaaaatca aggggagatt
    22561 ctagattcaa tagtaagtta ttcactagga catgcaactc tagccacaag acaaaaagag
    22621 ggagcattaa taaaaaaatg attagtttac gtatcataat tttacagtgt ccttatcatt
    22681 ttcttaattt tggataaatt atcattgcta tgattaaaat caaaaaaacg acattcatcc
    22741 aaataatcaa tttttttatt tcttcgctaa caaaatcata ggctaaaaaa gttatggatg
    22801 atataaatag acatacaaaa aaaataataa caaaaatttt ttccatttta atacccatat
    22861 ctagttacca caaggcgttt aaatttgggt ctctcctatt tacatcattg ttggcccaga
    22921 ttgttgtaat agcatcgcca attgacatcc aagctgcaaa tccattaata gcagacagtg
    22981 caaatcctgc cactctattt gcaactcgta ccccaacata tcttgcagct gctccagcaa
    23041 ttgcgcttgt aactcgccgc aaaccataat tacgaatata atttctaact agactgattg
    23101 ctcctccacc taaaacacca ttaaaagcta tattaatggc tgttgcaaca ggccatctca
    23161 gaatagaaaa tcccccatca agatacatca tctcttcttg ctcaagagca acataattat
    23221 ttggtaatac gagttccatt tattttctcc ttttttatta agcatagtta ggatagtttc
    23281 ctaacaagtg atagacgact gtgtttttat cacttagcta cctatataag atatcctttc
    23341 tctaccttat ttgtttttat aggttaccta aggtttaaaa tcaattattg tttgaaactt
    23401 aacagttcta aaccactagc aataaataat tgcgaactca ctaatactat ttcaaaattt
    23461 attttttttg acttagtaac gcaattccaa ttagcaatac acctaatata aataaaagta
    23521 tttcccaaaa tttattctca gttttaataa gtggaataag atacatactg actaatatgc
    23581 aacttgcccc tataatggca aatattattc tggttttatc tcctaattga aacatgtttg
    23641 atccccatat acacttcaag caaaagttgg atttctgaaa tggctaaaga taaagataag
    23701 ggttgcgagc tatttaaact atcatcaata ttctgctcga ttaaaacaaa gtctggtctt
    23761 acctctaaaa ttttctttaa cattgattca tatttatttt tttcattata atgccgtaaa
    23821 tatagattta attttataac atccaacata ccataaagtg atattggatg atttattttt
    23881 ttaaatcgct taacttctaa taaatcaatt tgttcacgca cactctctga aagatatggc
    23941 ttgatcaaac tgatataaga taaagccacg catggcaact cagattttga ttgcaatttc
    24001 caaatttcat gataatcctg aagattaaac tcacaatccc tcttagattc cagtattgtt
    24061 agtacttttg attttaacag aaataattgt tgattctcaa ttctataaag tttttgtact
    24121 aatgctatga taatagaaaa tggaataaga ggcaaaagca acgatttgtc atacacaaaa
    24181 gtaaagaaaa aatagtatga aattagtgtt gtaaagtaca agaagtagta aaatttaaac
    24241 agattcttag ttgtttgact ctccttataa aacactgcta ttcctggact aaatcccatt
    24301 agttggtgaa agagaattcg atagtatttc ctagctccta taatgatcac aaatataaaa
    24361 taaaaataaa ttggtcttaa tttacaaaag attgaggaaa ctagtaatag caaagtatgt
    24421 aagcattgag acaaaatata gaataacggt atcgccaata caaaggttaa gatggcatga
    24481 gagggagttc ctaagatgtc caattttata aatactgggc tgacacaaaa tatcgtgctt
    24541 ataagcagta aaattattaa aattgtgtca aaaaaataac gcttattttt cattagtcta
    24601 ctttccattg ttaaataata ctactgctaa caccaagcca acttagcaca ttgcatcacc
    24661 taatcctgcg ctacttgtcc ataatccttt aatgtttcta ctaaaattat tccaatctcc
    24721 cccatcaaga tagcttattt atcctagaca acgcctactg caacagtata aataagattc
    24781 atcagccatc ttttctggca atcatatggg tagactaatg atatttctag ttactcaaaa
    24841 atatctagct atactagagt tatttctaat ccctaggaca cttgttaatc caaatgtaac
    24901 aaattttcac cccttaatag gactctttct ggaaaaaata taaggtctat ctttataaaa
    24961 aaatctatca tattgggatg gcacgcatct ggaatttaaa caagctataa attcatttat
    25021 aactactatt tgtttagagg caacagcatc ttgtataccg tcctcgaaag aaccatcttg
    25081 taattccgaa atatttttgt ttaaatattg ttttgacaaa tctcttaatg cttcattatc
    25141 gtaaatgatt cccaaaaatc caaccttata tagtaaataa tttaaactta caaagtaatt
    25201 gaatcccata gtatattttt ctttataaag caaaggtaaa actttataaa aaatatctaa
    25261 gtcaacctca ctctgattct gaagcaagta ggagtcaagc aaattttcaa aaatagctaa
    25321 caatatgatt ggtgtaaagt ttttgtattc acatgtcaag tattctgagt atcgtgcaga
    25381 tgatatttct tttatataac tttttgaaag caagattttt tcaaattcat catctattat
    25441 taatcttcta tttccaatcc aagcggtatt accacccaaa taagattgtg caaatagcaa
    25501 tatgtaagaa aatatgaacg taaatactga aagaggtaga attctatgcg taaaaaaata
    25561 gacgataatg gtagccagga gtaaagatat ctctcgtgac aatcgaattc ttttcagcat
    25621 cttttttaac agtccgtaag gttgtccttg gcaatattct tgaactaaat taatcggaat
    25681 gacatctctc accatttctg gaaagtagag taagtttata ggttgaaatc tccagctccc
    25741 atcataagta aatggatata gaaccaaata cttaaaagat ttttttctta taaacttaat
    25801 tatcacaata tgaatgactg ttgcaatgaa gtatattaaa tataaaagta aaaccgccat
    25861 caatatactt acaaaaatcc ccttggaatc aatcaatgga aaataaaata ttgcaactag
    25921 aagcgaataa agtcccgcta ataaatattt ctgatcatct ttcatttaaa acaccatatt
    25981 atttactaag aatgcatcaa tacaatagag caactctgta agtcaatatt tgataaagca
    26041 aagctttaaa cccttcccca gacgttagct tttattcaac ccactacagt tgacaaggag
    26101 cccaaattat tgataaaaac tttagtcatc atcgtctcta taaaaatatt ttctatacac
    26161 tcttgataat accaaaatta atgccaatat cataccaaga gctataataa tagaatttat
    26221 tagatttatt ttagtatatc caatcactag tccaataatt ggactagcag acatgcttag
    26281 atataataaa aataacaaaa aatgaatttc accaattcct gcaaaaaaat gtttcatagc
    26341 tatagtttta cgcccataaa tacccatcaa atttaccgtc tacgatatct aaaccatatg
    26401 caatggctcc tcctaatgag aagacttcag caacagtagc cacaatatta agagcattag
    26461 taatagttgc catactaact ccaccaatat atcttgttat agcacttagt tacctagata
    26521 agatatcctt tagcttgctt ccaaaattta agtctacacc tataatatga gttcatatta
    26581 gtactgctaa atcctatcta tagtaatgtc aaacacctaa ataaagtcat ctctccaatt
    26641 cattcaagaa atgaataaag gcaaaaaatc tttaaaataa gaaaagtgca tattatcagg
    26701 tgttcaaaaa tattgatgat atacgttata tagatagaaa gatttactca atctcacttt
    26761 caaattgagt tttttcccaa cctcgttttt aatttatatc ttcaataaaa tctaatgacc
    26821 tagttgatat gtcatatgga ataatattat ttaatctgta atttttttaa aaaacttaat
    26881 aataaatttg ctccactgat tgctatcaat atttcaattg gtaaaaaata gtaattccaa
    26941 ataaaatgag aaatcagcaa tgatagaaaa ataacaatat caattttcct gttgttgaca
    27001 tactctgtaa ttttatgata caggaatgca acaataactg aaattaaaac aatcaacata
    27061 agattattaa cctattctca attgattatc acgtcgccca tcccagccat caataatatt
    27121 ggtaaaaatc caatcagctc cagcaccaat tccagcagat gcaatacttc taataacagt
    27181 atttgcaaaa gcatttccaa tatgaattcc taatactcct aaacctttaa caatcccagc
    27241 taccagtgcg gagcgtaatc cataagatgc aagaactagt tgaaggcctc cacctcctgc
    27301 tgctgctaat gctgcatatg ctgcaccagt aatggctcct gtaattgccc acctgggtat
    27361 atatatagcc cccccatcaa ggtacatcat ctcttcttca tcaatcacaa cataattatt
    27421 tggtaataca agttccattt attttctcct tttttattaa gcatgcttag gatggtttcc
    27481 taacaagtga tcgcaggctt tgtttagtta cctaaattag acttccttcc tttatcttat
    27541 tttaaatatt taaaaccagt tactgcttga agcttaacag tttacttaat tcaaataaca
    27601 gctaatcact gattccctga ttttatcaaa tatactaata acaacaattg tgatacgatc
    27661 atcattataa gaacaacatt taacgaatca aagtttttcc gagataataa taaagcaaca
    27721 gcaagcagta ttattactaa agattgaata actactatta ctcttaacat tttatcctcc
    27781 actaacaact caagctccct tacattatat cgaccagccc catggaaaga ttatagctag
    27841 actaatcaat gatataatac atactagaat acaaaatatt tttttattca tactttttct
    27901 cctatcttta ttttctacct acatcatacc tcttattaag ctcatttcaa aattacgtta
    27961 acttttttca cgaaaaggag acaattatgc gttatgatta tggatagcgc tttcaaattt
    28021 ttaaactcct atcccatcct tttatctata ttatgagcga aaatataata actgtcaagt
    28081 aactaaagtg aattttataa aaaaattaca agccaaattt gtaaagttta cactaagccg
    28141 ctagggcaat cgtctatcag aatgtccgtt tatttgtcaa taatccgaga aaatcttgca
    28201 acgcttagaa gtctataaaa actatcaaca tttatatgac ttgcgaatag caatcctgct
    28261 caacctttcc acactctatc tatacaatca agataaaaac atgtgtaagc aaatctgcta
    28321 cactttactg gaggacgcca agaataagaa aagctacgat aggctggcta tctgctatgt
    28381 ccgtattggg atttgtaggg atgatgcgaa acttatccaa aaagggttct cccttctgga
    28441 gctaaccgag gaaacttcta tactgtttca tctcaaaaaa gaagtagaga tctattacca
    28501 agcgaaggaa agataaaaaa gccgagggat ttcctcgact ctttacatat tatttgttcg
    28561 ttagttctta ataccagcta ttgttaagcc agaagttttt agctctgcca agccacatag
    28621 tgtgtttact actatgtgtc catgtcacca tgaatcgccg aacgatttaa cgagaaagta
    28681 tgacttttcc gtttatccca actcaattat gacatttttt tcaaaagtca atatatctca
    28741 ctttttcaac gacaagaaag aggctgataa tctaccaacc tcttattctg aacccatcac
    28801 tccatcactt tttagcttca ttcgctttct tagcgactgc aatctggtat tcgacttggt
    28861 cattcccctt accggtacaa ccatgagcaa ttgtagtcgc tcctatctga tgcgctattt
    28921 caaccaattt tttagaaatc agagggcggc tcaaggcaga taccaaggga tacttttgtt
    28981 cataataggc atgtgactga agagccacta gcacataatc tgtagcaaat tcgtccttaa
    29041 catcaatgac ataagattct actgccccaa ccttaagagc cttatcatgg atgaaatcta
    29101 agtctttccc ttcacccaca tccatacaaa ctgaaacaac atcatagtct ttctttaacc
    29161 aggtaatagc aactgatgtg tccaaaccgc cagaataggc caaaattact ttttctttac
    29221 tcatgttctt ttccttcttt ctatttttca atggatgctt taaaggcatc ctcaatgagt
    29281 ttgtctaatt ccccagactc cttcaacttt tgaatggttt tatcgactgc ctctttcaat
    29341 tccttgctat cttttttcat ggctaccgcg taggaatcat cttgctcttt ttcaaaattg
    29401 aggtctgcga ttgctaaatc aggattattt tccacaaatc ccttggaaac aggttcttca
    29461 aagataacgg catccacttg tcctgatttt aaatctgtga ttaaattccc atttttaggc
    29521 agagatacga gggaagaatt ttgtagcaaa tctttcgcca tcgtctcttg aatcgaacct
    29581 ttctgcgctc caaccttttt ctgcgccaag tcgtttacag actgataagt agtcaagtca
    29641 gattttttga caatgagttt attttttgca gtatagtagg gaatggaaaa gtcaaacacc
    29701 ttgctccgtt catctgtctt agaaacacct gatatggcaa ggtctgcttt tcctgattga
    29761 acactagcca gtacattatc aaaactcatg ggagatagtt ccaattcgac acctagttct
    29821 gttgcgatag ccttggctaa ttcgatatct gaacccacaa tctgattttt cccatcaacc
    29881 actttttgat attcaaatgg agcaaaatct ggattgaggg ctacaaccaa ttttcctttg
    29941 gacttgatgg cttcaattcc agccgattga ttgttactac aagcaaatag tagggggagc
    30001 atcactaaac caaacatcgt catcaacacc ttcttcatct tattcataac aaagccttct
    30061 ttatgtttat tcttttttat tgtataaata atactcctat actcatatac tcatcctttg
    30121 tcaagcctaa attgaaaaaa ttttcaattt gaaacaaaaa aaaacctaga aatgctacat
    30181 aaaatgtcat tcctaggcgt atttatgcta tttttctctg gaaaacatga gtattcagcc
    30241 agtcaaaagg agctgaatga actcattttc cctcgcccaa ttcaatgaca cgatgacatt
    30301 gttgggctac ataagcatcg tgggtcacaa taatgactgt tttcccttct cgattcatct
    30361 ctaagagaaa cttcaagacc aaatctctat tttcaggatc cagcgaacct gtaggttcat
    30421 cggctaaaat cagctggctg ggttttaaga tggctctagc aactgcaatt cgttgttgtt
    30481 cgcccccaga caactcggag accctttgat gcaaagtagc tgacaaacct actctctcta
    30541 aaatctcttc cacctttttg agcttgtctt tcttaggcaa tttcacatat ttcagcgcca
    30601 gcatgagatt gtactcgacc gtttcatcat caatcagggc aaaattttga aacagataag
    30661 agatatgttc acggattatt gtttgcgact tagcagaatt aaccgctaga tttgtctgac
    30721 caaaaatctc ataccgtccg ctataatcac catctatcaa acccaataaa tttaacaagg
    30781 tcgacttccc actaccactc ttaccaacaa tagctaccaa atccccctga tcaatcctga
    30841 gagataagtt atccaaaatc acttttcccc caatggtttt ggtaatattt ttcaactcaa
    30901 tcataagatg ccccctttca ataactctac tagacttctt ttctccatcc tagaagctaa
    30961 gcctagcaca aatagtatat ccagacatgt aaaacctgca aacagtagaa gtggtaagaa
    31021 cgcatgggca aagaaaatca agactagaag agggaaacta tagcccagca agagcagaac
    31081 gaggagagga cggtagcgat cgaccagttt ccaccccata aacttcttgg taatgatatc
    31141 cctgcgcttc aataagaaag ttgttactag taagaagtag gaaatcatca tgctaaggag
    31201 accaaacaaa gcaaagagta ggttaaaatt ccgaacagca tctctataag aatccacttt
    31261 ctcttgttga atggcttgaa tagatgaaaa ttttaaataa tttccatctg acaatttctc
    31321 aactaactct gtaatctctt tttgatgttg aaccgtattt tcaattttaa tcggattatt
    31381 taagccagtt gttgacaggg aggctttctc atcccacatc atatcagaat cattgaccaa
    31441 gctaataatt ggattggaga gattttcctt tcgcttatca ctatatggga aaaatgacca
    31501 atctccttca taataggcaa tctcgacatc catctcctct atcgttcgtt tttgctgctc
    31561 ttcatacttc atcgaatgaa aggcaattaa cttccccaag agctgatttt tatcttcttc
    31621 acctttcgta cttgctggca tcaaaataac ttttttaata ccggtatctg gtagcttgaa
    31681 tcccttgctc tttagaaaat tgcgattggc atagtaaaca tccaccgtat ctgttaactg
    31741 atattgctga atctgttctg attggacaaa attttttaca ggaagactgc tactctgcac
    31801 atagcccgcc tgcgtttttt ctaccaaatc ctgataaaat cgatagaaat aatctgtaga
    31861 tttccctgac cctgctagct cttcttgcca cagattatca ttgagtttga aggtttctaa
    31921 ggtcaggtaa ttaccttgac ttacccactg ttgctgataa gcaagttctt tgttttcttg
    31981 ttctaaactt ctgcccaccc caatcagtaa ggccgtcagt aaaatagttg tccctatttt
    32041 catcacataa ttgaagataa gaccaaattt gaaagatgaa aaacctttca gcagagagct
    32101 gattgtcatt ttttggatta agaggtaagt caaccaactg ataaagagat aaagctgcaa
    32161 cagcaaaaaa tgagacaacc acagcatagg aaacaaatct tttggcttat aatcaagcaa
    32221 gaaaaacacg cctagattga tcacaagagc cccacctagg aggaggtaaa ggttgccttt
    32281 tacaacatca gctaaaacag ccctatcttg aaaaccaagt aatttttgta ccccaactct
    32341 tttcatctcc atcatcggtt gatacactgt cactaacaca agaagcaaaa tagccaagac
    32401 aaaaacaatg gcagataaaa gcaaatctcg atttatgact tccactgcac ttttgtaggt
    32461 cggctctagc aaggtagcct ggtctatctt gaaaaaatcg ctccatttct gtacaatcct
    32521 atccttgtcc atctcttgtg tagaagttat cgtatagcga ccatttaaac tacgagatgt
    32581 atccttgata taggtttgaa aagtcataag ctgaataggt ttggctttta gaaaggtcgg
    32641 aatcgtacca agtttattgg aaatttcttt attactatag actccttcac catctgtggt
    32701 aaaatcaaga gaagaaatcc caaactcttg gtaggggaag gtatctttat caaaaacacc
    32761 agacttgacc acctcatcac cactgtctgt tttgatgatg gagactttat actcctttga
    32821 tacatcctca aaaaatcgaa gaacagacgc tgcaggttcg ttaatatctt tcaaatacaa
    32881 atccaaagaa tctacagtct ttcccatttc ttgaatccga accacttctc gtgtatagtt
    32941 tacattaaaa acaaaaaaag tggtacacag aagcaggagt aacatacaga aattactgat
    33001 ttttttcata aaagtgcctc cactacagtt ttccctctcc aaataggaga gggaagaatt
    33061 ttactcaaat ccatagaaat attccattcc tgttggcgga atcttggtga gggaagctct
    33121 agcccatgcc tcaggttttg cataatcctt agaggttcta cccccatgtc taacagttgc
    33181 tgtatgatat cgagtagaat gtaagtaatc agaatatcca aaagttcctg tccaacctac
    33241 tccatagttc cattgaccac cctcaaccca tactgctaaa gcatttgtag tagcaagtat
    33301 accacatacc attaaagatg caacaccaat tttaactaat tttctcatga tttatttctc
    33361 ctattatcga gagctgttcc gtaaaaacag ctatagtaat ttatcaacaa gtatcgtagt
    33421 ccattggact caccttcctt ctatctcatt tcatttttta acaacgaact tactcttaac
    33481 cgggagaatg gtgcgcttct gtatcaggtc cttgaacaac cagagtagta ttaagcacac
    33541 tctaactatt actcaagaat cagtccaata aacaatatgg atagcgcttt caaattttta
    33601 aactcctatc ccatcctttt atctatataa taagcgaaaa tataataact gtcaagtaac
    33661 tgaagtgaat tttataaaaa aattacaagc caaatttgta aagtttacac taagccgcta
    33721 gggcaatcgt ctatcagaat gtccgtttat ttgtcaataa tccgagaaaa tcttgcaacg
    33781 cttagaagtc tataaaaact atcaacattt atatgacttg cgaatagcaa tcctgctaaa
    33841 cctttccaca ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctacac
    33901 tttactggag gacgccaaga ataagaaaag ctacgatagg cttgctatct gctatgtccc
    33961 tattgggatt tgtacagata atgctaaact tatccaaaaa ggtttctcac ttctggagct
    34021 gaccgaggaa acttctatgc tgtctcatct caaaaaagaa gtagagaccc attatcaacc
    34081 aaagaaatta taaaaaaagt cgagggagct cctcgacctt ttacatatta tttgttcgtt
    34141 agttcttaat accagccatt gttaagccag aagtttttag cagcagtcca tgaaccgtaa
    34201 cgtcctgcaa cgtaggcatc tgctacacgt tcttggtttt cagctgagta gtcaccgttc
    34261 aggtatgaat ctgttaattg gtaacgtccg atataacgtc catttgtagc tgtatagcta
    34321 ccacctgatt ctttttgagc gatccattct ttggcttctg cttcagatcc gcttacagtt
    34381 gaaacaactg tttcacttac tactggagct gaaacagttt catcttgagc ggctggtgcc
    34441 gcataagtag ctggcgctgg tgttgcaaca ggcgctacag ggccatcgat aaccaactct
    34501 tgatcaacat aaatcaaatg aatgttatca atgtggttgt tttctgccaa tttttcaact
    34561 gttgtgttgt gagtttcagc gatttctgaa agtgtatcac cttctttaac agtgtaagtt
    34621 gatgattctt gagcagatac aaatgatgga gcaaatactg caaacaaggc agctactcct
    34681 gcaagagttg ctttaatctt tttagttatt gatttcatat tcgaaaattc tccttctttc
    34741 tatagttcta tcataccctt taaatattac cgtttcttga cacttttatg tagaaatatt
    34801 acaaaattat tttttatttc cctaaataag gtgttttttg tcataaaaga tactattttt
    34861 atgctatttg aggtattaga aaggttttca tccacaatta aagccaagcc cctcattctt
    34921 tgatataata gagataagaa tttttataag gggaaactga tgaaatcact tcgttttcaa
    34981 tctgtctttg atatcatcgg accagttatg attggcccat ctagtagcca taccgctggt
    35041 gctgttcgta ttgggaagat tgtctcttcc atttttgatg atactccgac agaagttgaa
    35101 ttccaacttt ttaactcatt tgccaagacc tatcgtggtc acggaacaga cctagccctt
    35161 gttgcaggta ttttaggaat ggatacagat gatcctgaaa ttccaaatag tctggaaatt
    35221 gcccacaagc gtggtatcaa gattgtctgg accattcaga aagacagcaa tgcccctcac
    35281 cctaacacca ctaaaattac tgttaaaaat gcccacaaga ccatcagcgt gactggtatt
    35341 tctatcggtg gaggaaatat tcaggtaacc gaactcaatg gttttgccgt ctctctcaat
    35401 atgaatacac cgactatcat catcgttcat caagatattc caggtatgat tgcccttgtt
    35461 acagaggcgc tttcccgcta tggtatcaat atcgcccaga tgaatgtcac tcgtgaaaaa
    35521 gctggtgaaa aagccattat gattatcgaa gttgacagtc gcaactgtga tgaggctatc
    35581 gaagaaattc gaaaaatccc tcatctccac aatgtcaatt tctttaaata ggaggaagca
    35641 tgttttattc tatcaaagaa ttggtcgagc aagcagatct agactttcaa ggaaatgtcg
    35701 cagaactcat gattacaaca gagtttgaat tgaccggtcg cgaacgtgaa gaagtcttcc
    35761 ttctcatgga acgcaatctg gaagttatga aagcctctgt ccaacttggc ctcaatgaaa
    35821 ataaatctcg tagtggcctg acaggtggag atgctgccaa attggatcac tacatcgaaa
    35881 acggaaaaac tctgtcagat tacacgattc tctctgctgc ccgaaatgcc atcgcagtca
    35941 atgaacacaa tgccaaaatg ggcttggtct gtgccactcc aaccgctgga agtgctggct
    36001 gtctgccatc cgttctcact gctgctattg aaaaattaga cctcagccac gagcaacaat
    36061 tggatttcct ctttgctgct ggtgcctttg gactagtcat cgcaaacaat gcctccatct
    36121 caggtgctga gggtgggtgt caagctgaag ttggttcagc ctctgctatg agtgctgccg
    36181 ccttgactct ggctgcaggt ggaacacctt atcaggccag tcaagctatt gcctttgtca
    36241 ttaaaaatat gctaggcctc atctgtgacc ctgttgcagg tttggtcgaa gttccctgtg
    36301 tcaaacgtaa tgccatggga gctagctttg ctttcatcgc agcagacatg gccttggcag
    36361 gtatcgaatc taaaatccct gtggatgaag tgatcgatgc catgtaccaa gtaggagcaa
    36421 gcatgccaac tgcctttcgt gaaacagctg aaggtggact cgctaccacc cctactggtc
    36481 gtcgcctcca aaaagaaatt ttcggagaat aagcttatca aataggagaa accatgacct
    36541 ctatcacagc gatttttttc gatttggatg gaaccctcgt tgatagttct atcgggattc
    36601 acaatgcctt tacctatacc tttaaagagc tgggggtgcc tagccctgat gccaaaacta
    36661 ttcgtggttt tatgggacca cctctcgaaa gtagttttgc gacctgcctg tccaaagacc
    36721 aaatttctga agccgtgcag atatatcgtt cttactataa ggcaaaaggc atctatgaag
    36781 ctcaactctt tcctcagatt atagacttgc ttgaggagtt atcgagcagt tatccactct
    36841 acatcaccac gacaaaggat acatctactg ctcaagacat ggcaaaaaac ttggaaatcc
    36901 atcatttctt tgatggcatt tatggttcta gccctgaagc accccataag gcagatgtca
    36961 ttcaccaagc cttgcagaca catcaactag caccagaaca agccatcatc atcggagata
    37021 ccaagtttga tatgctggga gctcgagaaa caggtattca gaaattggcc atcacttggg
    37081 gatttggaga gcaagcagat ctactaaact atcaacctga ttatatcgct cacaaaccct
    37141 tagaagtttt ggcgtatttt caatagcata gactgggtaa caattccatt tcagaagaaa
    37201 atgaagtaat actcaatgaa aatcaaagag caaactagga aactagctgc gggctgctca
    37261 aaacactgtt ttgaggttgc agatagaact gacgaagtca gatcaaaaca ctgttttaag
    37321 gttgtggatg gaactgacga agtcagatca aaacactgtt ttgaggttgc agatagaact
    37381 gacgaagtca gatcaaaaca ctgttttgag gttgtggata gaactgacga agtcagtaac
    37441 catatacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataagtctct
    37501 acataataaa acgcatatta ccaaggttgt gtaactggat actatgcgtt tttctttttt
    37561 attcaatgtg ggttgtttga ttagcaaagg cgataatagc ttgcttcaac tcatctccac
    37621 tgagagtgcg gaactctcca atcttttgat tgatggattc taaaggcatg acattaacct
    37681 taccaacgaa aatcttatcc ataacttgat tatcaacgag ttcggttgat accaagagtt
    37741 cttcgtagag tttttcacct gggcggattc caacttcaac gattggaatt tcactttcag
    37801 tgtggccact tagaagcacc atcttcttgg ccaagtcata aatcttgact ggtttgccca
    37861 tatcaaggat aaagacttcc ccatctttgg cataagcacc agcatggata accagacggc
    37921 tagcttctgg aatggtcata aagtaacggg tcatgcggaa gtctgtcacc gttacaggcc
    37981 caccttcagc aatctgacgt tcaaagactg gaatgacact accacggcta ccaagaacat
    38041 tcccaaaacg aactgcacag taggttgatt ggctacgttg gttaaagcca gtgacaatca
    38101 actccgccac gcgcttggtt gctcccataa catttggtgg attgactgcc ttatctgtcg
    38161 aaatcataac catcttagac actttagctt catcaacagc cttagcaaca ttgtaagttc
    38221 cacggatatt gtttttgaag gcttcttttg gattgcgctc catcatagga acatgcttgt
    38281 gggcagccgc atgataaaca atagcaggtt tgtactgctc aaagacttgc aacaaacgat
    38341 catagtcttg aatgtccgca atcacaggta cataatcaat cccttggaac ttacgaatca
    38401 attcatgata aacaaggtag attgagtttt ccccatgacc gagcaagaca atgcgttcag
    38461 gattgaagcg actaacttga cgacagattt cagaaccgat tgaacctcca gctcctgtga
    38521 ctaagatggt cttacctgtc agttctgcac ccagacgcga ttcgtcaaga cggatttcct
    38581 gacgacccaa aaggtccgta atatcaattt tttggaagcc agtacctgct tggtgaaggc
    38641 cctgaacaac agtttcaacc ttaggcatct tgtaacattt gacacccagc ttattacaca
    38701 tctgcaagat acgctcatat tctgacggat ccagcgacgg aatcgcaacg atgacacgct
    38761 cgatttgatg gcgtttggct aattcaggca gattgtcata agagcccaaa acaggaatac
    38821 caccaagttt ttgacccttt ttcttagaat ccttatccaa aataccgacc agttctaatt
    38881 cactggttgg atgttggtaa ctatccataa agagagcccc accatcaccg gcaccaatca
    38941 agaaggttcg acggtgttct ccatcaccac tacctttttt gcgtctggag tagattaact
    39001 gccaagtaat ccgtggcaat aaaatcaaga aggtactcaa caagataaag agaatgatga
    39061 aacggatgga gaagagtggc aagaaggcat aacagatact atatgacaag acactgctag
    39121 cagtcacacc aaaaaagatt ttcatgaaat ccgtaatctt gctgtaacga ctaatgctcg
    39181 cgttcaaccc ccaaaaacca atcatcaatt gatagaacag gaaggccaaa ctcgtataga
    39241 taatgtagtc aacaggtgct ggattaatca gcccataaaa taaaatataa gatacaatga
    39301 tggaaaccac catactgaaa atatcaaata ttccccagaa aacctgcttt tgttgtttat
    39361 ttaaaatttc caccagatca atcacataat ctgttagttt tttattcata gaaatctact
    39421 cctccttaaa agagttttac tatattgtta ttatagcata ttttgattta tttggcttat
    39481 tttatccaaa taaattattg ttctcttgta ctccttcttc catttaaatc ctctaattaa
    39541 acctacaatc gtcccaaagc cataagcaaa gtgaatggaa aataaaagaa agggcatcac
    39601 aattagaaat ccatttttat gttttaataa agtcagcaaa gtgagtaatg acaaaagtag
    39661 aaaataggca cctaatagta aagttatgaa tacgaatgtg atcggtaaca atgctagact
    39721 aaacacaaga ctcaaaacaa ataaacaagg aacatagtga aataatgata aacacttaaa
    39781 ctgaacatga cttgtcaagc caatccacaa accatttgaa tacttttgat gcagcatttt
    39841 cttgaatgtt ggtcgaatat actgataaga tagaatactt gggctatagc ggattttata
    39901 accatgttct cgaattctat aatgaatatc attatcttca gttcggccaa gttgctcatt
    39961 tactaaacca accttctgga aaacctctcg tttatacatc ccatgaaaaa tagaagaaac
    40021 atatctatcc tcggaactat ttcgataatt ggcaatgcta ctgccaaaca tattttcctc
    40081 aacaagatgc aaggtctctg cccattttcc ttttccttcg acaatcgtcg gtctaggccc
    40141 cccacagaca aattcacctt gttgaataat agccacattg ttcattacaa aactctcagt
    40201 aacttttgaa tgagcatcaa tttttaaaat aaggtcccct acagaatgtt taactcccag
    40261 gttaaaacca ctagcttgat ttttcttagg attgttatac aatctaattg agttaaactc
    40321 tgtatcttcc tttataaatt gctgaatgat agctgtggtc ccatctgtgg acatagcatt
    40381 tataaataga atttcaatat cctctttagg ataggtttga ttttttaagt cttcaattag
    40441 accaggcaga tatttttctt cattgtatgc actgattaca atggatacga gaagactttc
    40501 aacattttga gtcactacta ctctcctgaa tttttccttc caccattcta tcataatttt
    40561 caagactttc ccatttttat cttgaaagcc agaaacctta cttgacatta tagtgaaaaa
    40621 gccttaaaat aagctgttat taaaatcagc tagaagaggt attatatgaa aaagcaatca
    40681 ctcttttttg ttccaggtat tatcctgatt ggtgtttcct tgcgaactcc ttttactgtt
    40741 ttacccatta ttttgggaaa tatttcgcaa ggtctggagg tagaagttag ttcgcttggt
    40801 gtcttgacca gcctgcctct ccttatgttt accctctttt caccattttc tacccaactg
    40861 gctcagaaaa tcggcttgga gcatctcttc acctacagcc tcttcttctt gaccatcggc
    40921 tcacttattc gactaatcaa tctgcccctg ctctatctag gaaccttgat ggttggggca
    40981 agtgtcgcag tcatcaatgt cctgcttcct agtcttatcc aagccaatca accaaagaaa
    41041 attggttttc tgaccacctt atatgtaacg tctatgggga ttgcaacggc tctggcttcc
    41101 tatctagctg tgcccattac acaagccagt tcttggaaag gacttatcct tctcctcacg
    41161 ttactctgtc tagcaacttt tttggtctgg ctcccaaatc accgctataa tcatagacta
    41221 gctccacaaa ccaaacaaaa aagtcaaata aaggtcatgc gtaataaaca ggtttgggca
    41281 attattatct tttcaggttt tcaatccttg atcttttaca ccgtcatgac ctggttacct
    41341 accatgtcta tccatgcagg tctatccagt cacgaagctg gcttgctgac ttctatctta
    41401 tctctgatta gcattccttt ttcaatgacc atcccaagcc tgacaaccag tttatctact
    41461 cgcaaccgtc agctcatgct cactctggtt tcactagctg gtgtggtcgg catttccatg
    41521 ctctttttcc caatcaataa tttcatttac tggcttgcca tccatctcct catcggaacc
    41581 gcaaccagtg ccctcttccc ttatctcatg gtcaactttt cactcaagac aagcgcccct
    41641 gaaaagacag cccaattgtc cggcctatct caaacaggag gctatatcct agcagccttt
    41701 gggccaaccc tctttggtta cagttttgac ctgttccact cttgggtacc atctgtagct
    41761 gccctcttgc tcatcgatat cctgatgact gtggccctct ttacagtgga cagagcggat
    41821 aagatccttt aaacttctag ttttagctag aagtttttta tatataaaaa ttttacacat
    41881 ttctcttgac agggctttct tttagatgta caatgtatgt gtagaaaaat tatatataaa
    41941 aatcttacac attagaaaag gaggtttccc atgtactttc caacatcctc tgccttgatt
    42001 gaatttctca tcttggctgt actggagcag ggtgattctt atggttatga gattagccaa
    42061 accattaagc tgatcgctaa tatcaaagaa tccacactct atcccattct caaaaaattg
    42121 gaaggcaata gctttctgac aacctactct agagagttcc aaggtcgcat gcgcaaatac
    42181 tactccttga caaacggtgg tatagagcag ctcttgaccc taaaagatga atgggcactc
    42241 tatacagaca ccatcaatgg catcatagaa gggagtatcc gccatgacaa gaactgaata
    42301 cctgactcag ctagaactct atctcaagaa actacctgaa gctgaccgta tcgaagccat
    42361 ggactatttc agagagctct ttgacgatgc tggagtcgaa ggagaagaag aactcatcgc
    42421 tagtttggga actcccaaag aagcggccca cgaagttcta tccaatcttc tcgataaaaa
    42481 aatcaatgaa gcacccgctc aaaaaaataa ccgacaaatt ttacatatcg ccttgttagc
    42541 cctccttgca gcacctatcg gcattcctct gggaatcgcc atcctcgtga ccctgttcgc
    42601 aattcttgta gccgctttga ctgtcattct ggctttcttt gcagtttcca tactgggtat
    42661 catcggcgga ttcctatttt tagttgaaag tttcactgtc ctcgcccaag ccaaatcagc
    42721 ctttatcttg atttttggtt ctggtttact ggctatcggt gcttcttcgc tagttttact
    42781 tggcatttcc tatgcaactc gcttcttcgg tctactcatt gttcgtctgg tacaatttgt
    42841 tcttaaaaaa ggaaagagag gtaatcagca tgcgtaaatg gacaaaagga tttctcatct
    42901 ttggtgtggt gactaccgtt atcggcttta tcctgctttt tgtaggtatc caatctgacg
    42961 ggattaagag cctactttcc atgtccaaag aacctgtcta tgatagccgt acggaaaagc
    43021 taacctttgg caaggaagtc gaaaacctag aaattactct ccaccaacac acgctcacca
    43081 tcacagactc tttcgatgat caaatccaca tttcttacca tccatctctt tctgctcacc
    43141 atgatcttat caccaatcag aacgatagaa ctctgagtct cactgataag aaactgtctg
    43201 aaactccgtt tctctcttct ggaattggtg ggattcttca tatcgcaagt agctactcta
    43261 gtcgttttga agaagttatt ctccgactac caaaagggag aactctaaaa gggatcaaca
    43321 tctcagccaa tcgcggacaa accaccatca taaatgctag ccttgaaaat gcgaccctca
    43381 atacaaacag ctatatcctc cgaattgaag gaagtcgtat caaaaacagt aaactcacaa
    43441 cgcccaatat cgttaatatc tttgatacag ttcttacaga tagtcagcta gagtcaacag
    43501 agaatcactt ccacgctgaa aatatccaag tccatggcaa ggttgaactg actgccaaag
    43561 attatctcag aatcatccta gaccagaaag aaagccaacg aattaactgg gacatctcaa
    43621 gcaactatgg ttctatcttc caattcacaa gagaaaagcc tgaatcaaga ggtacggaat
    43681 taagcaaccc ttacaaaact gaaaaaaccg atgtcaagga tcaactcatt gcgagatctg
    43741 atgataatat tgatctaata tccacaccaa gcagacgttg acaaaaacgc ttacatttgc
    43801 tactatggaa acatatttat ctaactaaaa aggaggttct accatgaaac aagaatggtt
    43861 tgaaagtaat gattttgtaa aaacaacaag caagaacaag cctgaagagc aagctcaaga
    43921 ggttgcagac aaggctgaag aaacgatagc cgatctcgat acaccaattg aaaaaaatac
    43981 tcagttagag gaggaagtcc ctcaagctga agtcgaattg gaaagccagc aagaagagaa
    44041 aattgaagct cctgaagaca gtgaagcgag aacagaaata gaagaaaaga aggcatctaa
    44101 ttctactgaa gaagagccag acctttctaa agaaacagaa aaagtcacta tagctgaaga
    44161 gagccaagaa gctcttcctc agcaaaaagc aaccacgaaa gagccacttc ttatcagtaa
    44221 atctttagaa agtccttata tccccgacca agctccaaaa tctagggata aatggaaaga
    44281 gcaagtgctt gatttttggt cttggctagt ggaagcgatc aaatctccta caagtaagtt
    44341 ggaaacaagt atcacacaca gttacacagc ctttctcttg ctcattctgt tttctgcatc
    44401 ttcctttttc tttagtatct atcacatcaa acatgcttac tatggacata tagcaagcat
    44461 taacagtcgc ttccctgagc agctagctcc tttaactctt ttttctatca tctctatcct
    44521 agtagcgaca acactcttct tcttttcatt cctcttgggt agtttcgttg tgagacgatt
    44581 tatccaccag gaaaaggact ggacgctaga caaggttctc caacaatata gtcaactctt
    44641 ggcaattcca atcttcctca ctgctattgc tagtttcttt gctttctttg atagcctacg
    44701 atttacagcc ctcttgtgtg tgattagcat tggaatcatt ctgcttgcca gtctccatat
    44761 cattacaaga ccaagtcaag caagtgaaac cgactccttc tatcaattat tcttgtctgt
    44821 ccttgtgaac ggagttatta tcctcctctt ctttgtagct gaagtggcac tgattggaga
    44881 ttatcttcgt atcttggcct ttctttaaac ttcatactct tcaaaaatca aattcaaacc
    44941 acgtcagctt cgccttaccg tactcaagta cagcctgcgg ctagcttcct agtttgctct
    45001 ttgattttca ttgagtagca atcctgtcat ccttggcagg attttttcta tgtcaaaaaa
    45061 gcaagtcgat tgacctgctt ctgctttact tttcttgtgc taatgtttta aaatctttgt
    45121 ctaatatggg ttgcacttct atttgattgg cgtctagttg gtggtaaaaa gatgggggta
    45181 atacctctaa gaattttgca tagtccaagc gagcaatggc ttcatagtct tctggtttag
    45241 agccatctcc tgtgatttga accaagtcaa tctcccactg gacttcctta tccaccaatt
    45301 gctcaatata ggctgcagga acaaacggtt ctctcggtaa aactgtcttg actccttgag
    45361 ctagatggta aacgccatgc acttttcctt ctccatcctg atagaaggaa actctctcaa
    45421 agtaggcatc tgtctcttga accgcacgca cacgcgcttc aaactgagcc aagccatctg
    45481 cctctaaaaa gcttttcaag ttctcacgac taaagaaaat aggattaaaa attccttggc
    45541 aaatcgtaaa acgagctaca gggtctgcta gataggcttg aatacttgct tggaaataag
    45601 cttcaaaatc aaaaccatct agcccttcaa tatcagtccc tgtataagca agcaaagcat
    45661 ctaaaaatga cttgataatc tgccagtctg tctttgttag taggtcagga agatcgacac
    45721 ggtaagcctt ttgaccatca gcataactga ccttaaagag aaattgtgat tgccccacta
    45781 tcgcacactc gatatattcg agacgattaa gaggctgacg gagatagact acatcatagc
    45841 tatgtgactc caaaccgtct agcaaggcca agatcgactt ggcattcaaa atctcttgtt
    45901 ctcctaaaat gctctgttta tttggaataa aaaatgtttt cgccataact ggactccttt
    45961 gaaatcgttt acatacagta taccttattt ttctgaaaga tacaaaaaca aactttatac
    46021 tcttcgaaaa tctcttcaaa ccgcgtcagc ttcgccttgc cgtagatata tgtaactgac
    46081 ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag cagcctgcag ctagcttcct
    46141 agtttgctct ttgattttca ttgagtatta gatttttgag tacaaagcat agaaaaacag
    46201 cccctaagga ctgtttgatc ttatacagta gctgcctgat ccaagctttc accgatagcg
    46261 gctaggcgct caatcacttc agcttgtgtc aattcatttt ttgaaacata gcggttacgt
    46321 gggtgaacac ggcactcgtg tgagcatcca cgaaggtact tgtcttcatt ttcttctgat
    46381 gtcaagatac gacggttaca gaagggattt ccacagttga cataacgttc acatggtgtt
    46441 ccatcaaacc agtctttccc tacgatagtt gggttgacat ggttgacatc aacggcaata
    46501 cgctcgtcaa agacgtacat tttcccatcc caaagctcac cttgaacttc tgggtcttta
    46561 ccgtaagttg cgattcctcc gtgcaattgg ccgacatctt tgtagccttc acggaccatc
    46621 cagcctgaga atttctcaca gcgaacgcca cctgtacagt aaaccacgac acgcttgtcc
    46681 atgaattttt ccttgttatc acggacccat tgtggtaact cacggaagtt gcgaatatct
    46741 gggcgaatag ccccacggaa atgtcctagg tcgtactcat aatcgttacg tgtgtcaagg
    46801 acaacggtat ctttatcaag aagcgcttct ttgaactctt ttggagacaa gtaagcacct
    46861 gttgtttcaa gtgggttgat gtcattgtca aagtcgttgt cttccaaacc aaggtggaca
    46921 atttctttct tgtagcgaac aaacatcttc ttgaaggctt gttctctttc ttcgtcaatc
    46981 ttgaaccaga gatcttccat acctgggagg ctgtgaacgt agtccatgta tttttgagtt
    47041 gtttcatagt cacctgaaac tgttccgtta attccctcgt cagcgactag gatacggcct
    47101 ttaaggccga ttgatttaca gaaagccaag tggtctgcag caaattgctc tgcattttca
    47161 attggagtat aaaggtagta aagtaagaca cgaatatctt ttgccataag atttgttctc
    47221 ttttctattc ttaaattttc taaatttttt atttatccat actagtatac ctgcttgaga
    47281 aaacgaatgc aatttatttg actggaaatt gtagagggtt ctcgaaattt cctgaatggt
    47341 taaaataagg acaagagaaa acatggatat ctatatcctt gtgccaaaaa aaccactgcc
    47401 ctccccagac caacctgagg aaagcagtga ttcttatttt aggagttagg aatgaataca
    47461 cgaaatcaat ttagctgatt attttttgtt tttcaagaat tcatcgtatt gtttttgcat
    47521 ttcgttcaat actttttcgt aggcaccttc agatttcaat ttttccatca attctggaat
    47581 agctttatct gggtctacag taccagtgtt gatagctgta tcaaattgtt gcattgtgtt
    47641 agcaatagct gagatttcag atttcacatt gtcagtattg aagataaatc caagcgctgg
    47701 agattcttta gcttctgcca attctttctt agaattttcg atttgttggt ctgtaacgtt
    47761 ttcgttgatg taaaggatcc agttgttacc agtgttccat ccacccatgt gagtgtttcc
    47821 tttgtagcca tcaagaacgc gaacacggtt ttctttacct tcaatttttt cccagttctt
    47881 gccttctgga ccgtaaacaa gaccgttcaa gagttctgga ttcgtattca agaggttcaa
    47941 gatttccatt gatttttctt tgttcttaga gttgtttgag atgacaaagt tagcaacttg
    48001 tgttgtttgg tttttcttga tgaagttagt aattggtttg atttggatat ctttgttggc
    48061 aacacgtgaa agcaagctgt taccgtagtc agctggtcct actgtttctt cacgaacgaa
    48121 ccaagtatct tgttgaaggt caaaggaagt atcgcttgtt gcgacatctt ttggaatgta
    48181 gccagcttca tagaatttgt gaagagtctt caagtgttct ttgaaacgag gcacttcgta
    48241 acggtttaca actttagtag tatcgccttc aaggtcaata acgaatggaa gcccgtttgc
    48301 tactgggtag tcaaaattat cagatgggat gaaaacttta ccaatagcaa atggtactac
    48361 gtctggagct ttttctttga tttgtttcaa gactggctca agagtttcgt aagaagtaac
    48421 acctgaaata tcgataccat atttggcaag gagagttccg ttgaaggcaa agttttgaga
    48481 tgatgctacg ttggctgcaa ctggtacagc ataaatctta ccatttacag tattaccctt
    48541 gatataagct ggatcaagtg ccttgtaaag gtctttacct tcttttttgt acaattctgt
    48601 caagtcagca taagcacctt tttgagcatt tacaatatag ttatctgcaa aggcgatatc
    48661 atagttttca ccagatgatg tgataactga cattttctta ccatagtcac cccagccaag
    48721 gtattggata tccaatttgg caccaacttt ttcttcgatg attttgttgg catttgctaa
    48781 caattcatcc aagttatctg gtttgtcacc gatttggtac attttgataa caggtttgtc
    48841 acctgaatca gcagcttttt tactgttacc tgtcaagttg ccacaagcag caagacctgc
    48901 agccaaagcg actacactag cagatgcaaa agcatatttt ttccagtttt tcatgataaa
    48961 aactcctttt tttattttta aacttataaa caatgtaatg atcttatact caatgaaaat
    49021 caaagagcaa actagaaaac tagccgcagg ctgtacttga gtacggcaag gcgacgttga
    49081 cgcggtttga atttgatttt cgaagagtat taacttcaca caagggaagt tgggaactga
    49141 gaaatgttat ttctcaataa gcactattct ttcacaccac cgatagtcaa accttttaca
    49201 aagtagcgtt ggaaaaatgg atacaaaatc gcgattggaa gggttgcaac cacaaccatg
    49261 gccatacgac ctgtttcttt cggtagagca actcccagtt gaccagtcaa gccgaccgct
    49321 ttggcaatgt agtccatatt ttgttggatt tgcatgagca aatattgcaa tggatacaag
    49381 ttgtcactct tgatgtaaag aagggcgttg aaccagtcat tccagaaacc aagagctgtt
    49441 aagagcgtga tggttgcgat acctggtagt gacaatggca aacagatttg gaagaaaatc
    49501 cgggcttcac tggcaccatc gatacgagcc gattctagaa tggcttctgg aatggtcttc
    49561 ttgaagaagg aacgcatcaa gatgatgtta aatggtgaga gaagcattgg aacaatcaag
    49621 gcccaaacag tatccccaag ctgaagcaca cgagtcacca tgatataacc tggtaccaaa
    49681 ccagcgttga acaacatact gagcagaacg aagatggtaa agaatctgcg atacttaaag
    49741 gttgtccgtg aaatagcgta ggcataggtt gttgtgataa agacatttgt caatgtccca
    49801 actacggtta caaagacaga gatgaagagg gcttgtagga ttttatcctt aaactgtgcc
    49861 aaaaactcaa aaccgtctaa gccaaattgg gatgggaaga agctatagcc gtattggagg
    49921 aggcttttct cgtctgtcac tgaaataatg ataacgaata caaaaggtag gatacaagag
    49981 agggcaatca aacccgaaat gatactgaag aagatatctg ctttcttact gaaggagtga
    50041 atgccgacat tatcaatttt ttctttttta attttctttt ttgccatatt ctcctccttt
    50101 ctagaacaaa gctgagtttg gatcgactcg tcttgcaagc aagtttgata ggataaccag
    50161 aatcaaacca acaacggatt ggtaaagacc ggctgctgca gccataccga tatctgctgt
    50221 ctgagtcaaa ccattaaaga catatacgtc caaaacgttg gttacattgt aaagctgacc
    50281 agcattgtgt gggatttgat agaagagacc aaagtctgcg cggaagatat ttccgactgc
    50341 aaggatggtc aatacagtta caagcggagt caactgagga atggttacgt tgcgaatacg
    50401 ttgccacttg ctagctccgt ccactgtcgc tgcttcgtag taggttggat caattcccat
    50461 gatcgtcgca tagtacatga cactgctata tccaaagcct ttccaaatac ctaggaaaag
    50521 taggagatag ggccagatgc ccaggtcagc gtaaaaattg acttctttga gaccaagact
    50581 ttccaataga tgattgaaca cccctttatc aatatttagg aaggcatctg taaagaaact
    50641 gatgataacc caagacaaga agtaagggaa caacatagaa gtttggaaaa tcttcaccat
    50701 tctcttagaa cggagctcgc tgaggataat ggcaatccct acagatacaa ctaaacctag
    50761 aaagataaag ccaagattgt agaggacagt atttcgtgtg ataataaagg cgtctcttga
    50821 actaaataag aatctgaaat tatcgagtcc gacccattta ctatttatga tactatctat
    50881 gaaaccatta ctggtcatgt ggtagtcttt gaaggcaacc acgttcccaa atactggaat
    50941 gtaaaagaat agaatcaacc agagtgtccc tggcaaaacc atcaagagaa agatccagtt
    51001 gtctctcaat gtttttgaaa actttttcat aatttcctcc ctttttattt tgatatccat
    51061 ctaaaaattc ttttttagac ttttgataac gattacatta ttagtatact cctatttgca
    51121 ggttaggtta aactcctaat tatagaaaaa actccacaaa ttatgtagca gatttaaaac
    51181 tttatcacca ctatcaaaca aatgtcctaa atcaattgtt tattttatct ctattagccc
    51241 agtgatggcg tcactctgtt ataagcatcc aacaacgggg tatactgaaa aatctccaga
    51301 ctagggaact cagagatagt tcctaatctg gagattttta atatgttatt aggcgtttgc
    51361 tttcaactta gcaataacct ctttaagatt atcaatcacc tctgcttcag tatgctcaga
    51421 gctttttcat ctgccaagaa caaaactgct ttttgaagtt ctttttgaga gttttcaagg
    51481 acatccttat ctactgtttc aaggtttgag tctttaagaa gtttacttaa ttccttggct
    51541 aatttcttga gtttgatttg cagactcatc ttctcctgct gtttctttgc ccgctgtttg
    51601 tcctccatcc ttagttgctg actggctttc cttaatggac tctagggaag caatggcatc
    51661 tttgactgtt tgcaaaatat cacgtaaacc ttgctctgtc aaactatcat ctgcaaaagc
    51721 tttcttagcc tctgccaaaa ccagacgtgc tgaatctgtg gtaggattcg atacacctgt
    51781 caatgatctc aaaagatttt ctaaggtttg agtctgctta ctaatactag actaaaatca
    51841 aaaagcatta tataacagtg atatgaaatc aactaaagaa gaaatccaaa ctatcaaaac
    51901 acttttaaaa gactctcgta cagctaaata tcataaacgc cttcaaatcg ttctatagta
    51961 aaatgaaaca agaacaggac aaatcgatca ggacagtcaa atcgatttct aacaatgttt
    52021 tagaagtaga tgtgtactat tctagtttca atccattata tttcgtctga tgggcaaatc
    52081 ttaataaaga gattatagag cttttatagt gatttgaaat aagatgtgaa caactctatc
    52141 aggaaagtca aattaattta tagaaatatt ttagcagcca aggtgtactg ttataaattc
    52201 aatacact
//
LOCUS       DAVLHM010000006        51855 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLHM010000006 DAVLHM010000000
VERSION     DAVLHM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.006"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..590
                     /locus_tag="VXE45_000388"
     CDS             <1..590
                     /locus_tag="VXE45_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788486.1"
                     /translation="SLIKLDQMGLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSH
                     GANLSLYEYCLLDNSLTLKNDWNYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVP
                     FVFLDLIGEGKKEYEMFFQWLNFFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIF
                     KICPGVYKGLSYYLMKFLLKSFSNEYLKTTDEVNR"
     gene            587..1765
                     /locus_tag="VXE45_000389"
     CDS             587..1765
                     /locus_tag="VXE45_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0788487.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            2190..2423
                     /locus_tag="VXE45_000390"
     CDS             2190..2423
                     /locus_tag="VXE45_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0788488.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            2706..4655
                     /gene="mutL"
                     /locus_tag="VXE45_000391"
     CDS             2706..4655
                     /gene="mutL"
                     /locus_tag="VXE45_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0788489.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(4980..5447)
                     /locus_tag="VXE45_000392"
     CDS             complement(4980..5447)
                     /locus_tag="VXE45_000392"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0788490.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIAVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(5448..6653)
                     /locus_tag="VXE45_000393"
     CDS             complement(5448..6653)
                     /locus_tag="VXE45_000393"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0788491.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(6673..7308)
                     /gene="ribE"
                     /locus_tag="VXE45_000394"
     CDS             complement(6673..7308)
                     /gene="ribE"
                     /locus_tag="VXE45_000394"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0788492.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(7293..8393)
                     /gene="ribD"
                     /locus_tag="VXE45_000395"
     CDS             complement(7293..8393)
                     /gene="ribD"
                     /locus_tag="VXE45_000395"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0788493.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(8528..8642)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            8799..9392
                     /gene="ruvA"
                     /locus_tag="VXE45_000396"
     CDS             8799..9392
                     /gene="ruvA"
                     /locus_tag="VXE45_000396"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0788494.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            9402..9965
                     /locus_tag="VXE45_000397"
     CDS             9402..9965
                     /locus_tag="VXE45_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0788495.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            9962..10639
                     /locus_tag="VXE45_000398"
     CDS             9962..10639
                     /locus_tag="VXE45_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0788496.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIATYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVDYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(10794..11825)
                     /locus_tag="VXE45_000399"
     CDS             complement(10794..11825)
                     /locus_tag="VXE45_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0788497.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(12080..12763)
                     /locus_tag="VXE45_000400"
     CDS             complement(12080..12763)
                     /locus_tag="VXE45_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0788498.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(12775..13719)
                     /locus_tag="VXE45_000401"
     CDS             complement(12775..13719)
                     /locus_tag="VXE45_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0788499.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            13851..16682
                     /gene="uvrA"
                     /locus_tag="VXE45_000402"
     CDS             13851..16682
                     /gene="uvrA"
                     /locus_tag="VXE45_000402"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0788500.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            16675..17736
                     /locus_tag="VXE45_000403"
     CDS             16675..17736
                     /locus_tag="VXE45_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0788501.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            17868..18266
                     /gene="spx"
                     /locus_tag="VXE45_000404"
     CDS             17868..18266
                     /gene="spx"
                     /locus_tag="VXE45_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0788502.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            18332..18901
                     /locus_tag="VXE45_000405"
     CDS             18332..18901
                     /locus_tag="VXE45_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0788503.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            18988..19254
                     /locus_tag="VXE45_000406"
     CDS             18988..19254
                     /locus_tag="VXE45_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0788504.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            19258..19677
                     /gene="ruvX"
                     /locus_tag="VXE45_000407"
     CDS             19258..19677
                     /gene="ruvX"
                     /locus_tag="VXE45_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0788505.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            19693..19998
                     /locus_tag="VXE45_000408"
     CDS             19693..19998
                     /locus_tag="VXE45_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0788506.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            20411..21661
                     /locus_tag="VXE45_000409"
     CDS             20411..21661
                     /locus_tag="VXE45_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0788507.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            21658..22215
                     /locus_tag="VXE45_000410"
     CDS             21658..22215
                     /locus_tag="VXE45_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0788508.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            22361..23893
                     /gene="cls"
                     /locus_tag="VXE45_000411"
     CDS             22361..23893
                     /gene="cls"
                     /locus_tag="VXE45_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0788509.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            23971..24114
                     /locus_tag="VXE45_000412"
     CDS             23971..24114
                     /locus_tag="VXE45_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788510.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            24151..25689
                     /locus_tag="VXE45_000413"
     CDS             24151..25689
                     /locus_tag="VXE45_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0788511.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            25809..28016
                     /gene="nrdD"
                     /locus_tag="VXE45_000414"
     CDS             25809..28016
                     /gene="nrdD"
                     /locus_tag="VXE45_000414"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0788512.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            28028..28168
                     /locus_tag="VXE45_000415"
     CDS             28028..28168
                     /locus_tag="VXE45_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788513.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            28212..28718
                     /locus_tag="VXE45_000416"
     CDS             28212..28718
                     /locus_tag="VXE45_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788514.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            28711..29301
                     /gene="nrdG"
                     /locus_tag="VXE45_000417"
     CDS             28711..29301
                     /gene="nrdG"
                     /locus_tag="VXE45_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0788515.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            29298..29915
                     /locus_tag="VXE45_000418"
     CDS             29298..29915
                     /locus_tag="VXE45_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0788516.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            30181..30489
                     /gene="rpsJ"
                     /locus_tag="VXE45_000419"
     CDS             30181..30489
                     /gene="rpsJ"
                     /locus_tag="VXE45_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0788517.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            30706..31332
                     /gene="rplC"
                     /locus_tag="VXE45_000420"
     CDS             30706..31332
                     /gene="rplC"
                     /locus_tag="VXE45_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0788518.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            31357..31980
                     /gene="rplD"
                     /locus_tag="VXE45_000421"
     CDS             31357..31980
                     /gene="rplD"
                     /locus_tag="VXE45_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0788519.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            31980..32276
                     /locus_tag="VXE45_000422"
     CDS             31980..32276
                     /locus_tag="VXE45_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0788520.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            32294..33127
                     /gene="rplB"
                     /locus_tag="VXE45_000423"
     CDS             32294..33127
                     /gene="rplB"
                     /locus_tag="VXE45_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0788521.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            33231..33512
                     /gene="rpsS"
                     /locus_tag="VXE45_000424"
     CDS             33231..33512
                     /gene="rpsS"
                     /locus_tag="VXE45_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0788522.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            33524..33868
                     /gene="rplV"
                     /locus_tag="VXE45_000425"
     CDS             33524..33868
                     /gene="rplV"
                     /locus_tag="VXE45_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0788523.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            33881..34534
                     /gene="rpsC"
                     /locus_tag="VXE45_000426"
     CDS             33881..34534
                     /gene="rpsC"
                     /locus_tag="VXE45_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0788524.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            34538..34951
                     /gene="rplP"
                     /locus_tag="VXE45_000427"
     CDS             34538..34951
                     /gene="rplP"
                     /locus_tag="VXE45_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0788525.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            34961..35167
                     /locus_tag="VXE45_000428"
     CDS             34961..35167
                     /locus_tag="VXE45_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0788526.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            35192..35452
                     /gene="rpsQ"
                     /locus_tag="VXE45_000429"
     CDS             35192..35452
                     /gene="rpsQ"
                     /locus_tag="VXE45_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0788527.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            35478..35846
                     /gene="rplN"
                     /locus_tag="VXE45_000430"
     CDS             35478..35846
                     /gene="rplN"
                     /locus_tag="VXE45_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0788528.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            35924..36229
                     /gene="rplX"
                     /locus_tag="VXE45_000431"
     CDS             35924..36229
                     /gene="rplX"
                     /locus_tag="VXE45_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0788529.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            36253..36795
                     /gene="rplE"
                     /locus_tag="VXE45_000432"
     CDS             36253..36795
                     /gene="rplE"
                     /locus_tag="VXE45_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0788530.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            36813..37082
                     /gene="rpsN"
                     /locus_tag="VXE45_000433"
     CDS             36813..37082
                     /gene="rpsN"
                     /locus_tag="VXE45_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0788531.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            37367..37765
                     /gene="rpsH"
                     /locus_tag="VXE45_000434"
     CDS             37367..37765
                     /gene="rpsH"
                     /locus_tag="VXE45_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0788532.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            37957..38493
                     /gene="rplF"
                     /locus_tag="VXE45_000435"
     CDS             37957..38493
                     /gene="rplF"
                     /locus_tag="VXE45_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0788533.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            38577..38933
                     /gene="rplR"
                     /locus_tag="VXE45_000436"
     CDS             38577..38933
                     /gene="rplR"
                     /locus_tag="VXE45_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0788534.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            38951..39445
                     /gene="rpsE"
                     /locus_tag="VXE45_000437"
     CDS             38951..39445
                     /gene="rpsE"
                     /locus_tag="VXE45_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0788535.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            39417..39641
                     /gene="rpmD"
                     /locus_tag="VXE45_000438"
     CDS             39417..39641
                     /gene="rpmD"
                     /locus_tag="VXE45_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0788536.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            39786..40226
                     /gene="rplO"
                     /locus_tag="VXE45_000439"
     CDS             39786..40226
                     /gene="rplO"
                     /locus_tag="VXE45_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0788537.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            40239..41549
                     /gene="secY"
                     /locus_tag="VXE45_000440"
     CDS             40239..41549
                     /gene="secY"
                     /locus_tag="VXE45_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0788538.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            41700..42338
                     /locus_tag="VXE45_000441"
     CDS             41700..42338
                     /locus_tag="VXE45_000441"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0788539.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            42455..42673
                     /gene="infA"
                     /locus_tag="VXE45_000442"
     CDS             42455..42673
                     /gene="infA"
                     /locus_tag="VXE45_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0788540.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            42698..42814
                     /gene="rpmJ"
                     /locus_tag="VXE45_000443"
     CDS             42698..42814
                     /gene="rpmJ"
                     /locus_tag="VXE45_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0788541.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            42832..43197
                     /gene="rpsM"
                     /locus_tag="VXE45_000444"
     CDS             42832..43197
                     /gene="rpsM"
                     /locus_tag="VXE45_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0788542.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            43215..43598
                     /gene="rpsK"
                     /locus_tag="VXE45_000445"
     CDS             43215..43598
                     /gene="rpsK"
                     /locus_tag="VXE45_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0788543.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43641..44576
                     /locus_tag="VXE45_000446"
     CDS             43641..44576
                     /locus_tag="VXE45_000446"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0788544.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            44588..44974
                     /gene="rplQ"
                     /locus_tag="VXE45_000447"
     CDS             44588..44974
                     /gene="rplQ"
                     /locus_tag="VXE45_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0788545.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            45239..45505
                     /locus_tag="VXE45_000448"
     CDS             45239..45505
                     /locus_tag="VXE45_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0788546.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            45515..46852
                     /locus_tag="VXE45_000449"
     CDS             45515..46852
                     /locus_tag="VXE45_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0788547.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            47096..47788
                     /locus_tag="VXE45_000450"
     CDS             47096..47788
                     /locus_tag="VXE45_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0788548.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(47891..49536)
                     /locus_tag="VXE45_000451"
                     /pseudo
     CDS             complement(47891..49536)
                     /locus_tag="VXE45_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(49526..50617)
                     /locus_tag="VXE45_000452"
                     /pseudo
     CDS             complement(49526..50617)
                     /locus_tag="VXE45_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(50630..51751)
                     /locus_tag="VXE45_000453"
                     /pseudo
     CDS             complement(50630..51751)
                     /locus_tag="VXE45_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        15682 a         9602 c        11270 g        15301 t
ORIGIN      
        1 gatctttgat aaaattagat caaatgggat tagaattgac aaatggggga ataatagaag
       61 tgtttattcc taatcatttg agaaagttga aaaattttat tgaagaggaa ttcaataaat
      121 ttagaaattc tcacggagct aatctaagcc tctatgaata ctgtttgctt gataattctt
      181 taactttaaa aaatgattgg aactattctg atttagttat gaaatttacg agtaattttt
      241 atgctgatat aaaagacttg ttcatggaaa attctgatat tgaaatcatc catgaagagg
      301 gagtaccttt tgtattttta gatttaatag gtgaaggtaa aaaagaatat gaaatgtttt
      361 ttcaatggtt aaacttcttt tacaaacagc ttggaatcac attgtatgct agaaatagtt
      421 ttgggtttcg gaatctaaca gtagagtatt ttggaattat tgggacagaa agatatatat
      481 ttaagatttg tccaggtgtt tataaagggt taagttatta tttgatgaaa tttttattaa
      541 aatctttttc aaatgaatat ttaaaaacta ctgatgaggt taatagatga aaaatttgat
      601 aaagttgcta ataattagat tgattgttaa cttagcagac agtgtatttt atatagtagc
      661 attgtggcac gttagcaata attattcttc gagcatgttc ttaggaatat ttattgcagt
      721 aaattatcta ccggatttgt tactaatctt ttttggacca gttattgaca gagtaaatcc
      781 gcaaaaaatt cttataatat caattttggt tcaattagca gtggctgtaa tatttttatt
      841 attattaaac caaatatcat tttgggtgat aatgagtcta gtgtttattt cagtaatggc
      901 tagctccata agttacgtga tagaagatgt gttgattcct caagtggtag aatatgataa
      961 gattgtattt gcaaattctc tttttagtat ttcgtataaa gtattagatt ctatttttaa
     1021 ttcattcgca tcatttttac aggtggcagt aggatttatt ttattggtta agatagatat
     1081 aggcatattt ttacttgctc tatttatatt gttgttgtta aaatttagaa ctagcaatgc
     1141 gaatatagaa aacttctctt tcaaatatta caagagagaa gtgttgcaag gtacaaagtt
     1201 tattttaaat aataaattat tatttaaaac cagtatttct ttaacgctta taaacttttt
     1261 ttattcattt cagacagtag ttgtaccgat tttttctatt cgatattttg atggtccgat
     1321 tttttatggt atttttttaa ctattgctgg tttgggtggt atattgggaa atatgctagc
     1381 gccaatcgta ataaaatatt taaaatcgaa tcaaattgtt ggtgtatttc tttttttgaa
     1441 cggctcaagt tggttagtag caattgttat aaaagactat actttatcac ttattttatt
     1501 tttcgtttgt tttatgtcta aaggagtctt caatattatt tttaattcgt tgtaccaaca
     1561 aatacctcca catcaacttc ttggtagggt aaatactacc attgattcta ttatttcttt
     1621 tggaatgcca attggtagtt tagttgcagg aacgcttatt gatttgaata ttgaattagt
     1681 gttaattgct attagcatac cttatttttt gttttcttat attttttata cggataatgg
     1741 attgaaagaa tttagtatat attagaaatg tttatgttca ttcaaaagca taatgactat
     1801 aactgaaaaa gaaaagtgat atctttaagg ttgttcttct tggtggtgag attcgtgaga
     1861 caacccaagc ttttgtcgga aagattacca atgctttgat ggataggatg tactttagca
     1921 agatgttttt agtggtaacg gtatcgtgga tggacgtgta ataacctctt ctttcgagga
     1981 gtattttact aaaaaactag ccttggagcg ttccccagaa acggacttac tcattgactc
     2041 ttcaaagatt tggggagaag attttgcttc atctgttcct tgaaaaaagt cacagcagtc
     2101 atcacagacg atagtactga acaaaactat gaagagttag aaatttatac gcaggtgatt
     2161 gtataaagga tctggaaata gataagaagt tgattagtat tgacctaggt ggtacaaata
     2221 ttaagattac tgttctttca aatgacggtg agattgaaac tttgtggagt attacaacag
     2281 atacaagtga gaaaggttct caaattatat cggacatcat cagttctatt aaaaataaat
     2341 tgaccgaacg gaatattcct gatagcgacc ttcttggaat cggtatggga agttgctcat
     2401 catactttcc ttgtaaatca taggggctat aaactctccg tctacttgtc ctgcaacaat
     2461 tgaagtctgc tcaaaacgcc gtccgctaat cttttcatag actttctccc ttttaggagc
     2521 ctagctttct agtttgttct ttgattttta ttgagtatac cactatttta ctccctctgg
     2581 caagggactt tgtctatgtg gagggattgg gctcctatgt ggtggagctt ttctgttctt
     2641 tctgaaatat ggtataatag cactaatcaa tttctaggaa aatagataca gaaaggggct
     2701 gaaagatgtc tcatattatt gaattgccag agatgctggc aaaccaaatc gcggctggag
     2761 aggtcattga acgtcctgcc agtgtggtca aagagttggt agaaaatgcc attgacgcgg
     2821 gctctagtca gattatcatt gagattgagg aagctggtct caagaaggtt caaatcacgg
     2881 ataacggtca tggaattgcc cacgatgagg tggagttggc cctgcgtcgc catgcgacca
     2941 gtaagataaa aaatcaagca gatctctttc ggattcggac gcttggtttt cgtggtgaag
     3001 ccttgccttc tattgcgtct gttagtgtct tgactctgtt aacggcggtg gatggtgcta
     3061 gtcatggaac caagttagtc gcgcgtgggg gtgaagttga ggaagtcatc ccagcgacta
     3121 gtcctgtggg aaccaaggtt tgtgtggagg atctcttttt caacacgcct gcccgtctca
     3181 agtatatgaa gagccagcaa gcggagttgt ctcatatcat tgatattgtc aaccgtctgg
     3241 gcttggccca tcctgagatt tcttttagct tgattagtga tggcaaggaa atgacgcgga
     3301 cagcagggac tggtcaactg cgccaagcaa tcgcaggaat ttacggtttg gtcagtgcca
     3361 agaagatgat tgaaattgag aactctgacc tagatttcga aatttcaggt tttgtgtcct
     3421 tgcctgagtt gactcgggct aaccgcaatt atatcagcct cttcatcaat ggccgttata
     3481 ttaagaactt cctgctcaat cgtgctattt tggatggttt tggaagcaag cttatggttg
     3541 gacgttttcc actggctgtc attcacatcc atatcgaccc ttatctagcg gatgtcaatg
     3601 tgcatccaac taagcaagag gtgcggattt ccaaggaaaa agaactgatg actctggttt
     3661 cagaagctat tgcaaatagt ctcaaggaac aaaccttgat tccagatgcc ttggaaaatc
     3721 ttgccaaatc gaccgtgcgc aatcgtgaga aggtggagca aactattctc ccactcaaag
     3781 aaaatacgct ctactatgag aaaactgagc cgtcaagacc tagtcaaact gaagtagctg
     3841 attatcaggt agaattgact gatgaagggc aggatttgac cctgtttgcc aaggaaacct
     3901 tggaccgatt gaccaagcca gcaaaactgc attttgcaga gagaaagcct gctaactacg
     3961 accagctaga ccatccagag ttagatcttg ctagcatcga taaggcttat gacaaactgg
     4021 agcgagaaga agcatccagc ttcccagagt tggagttttt cggacaaatg cacgggactt
     4081 atctctttgc ccaagggcga gatggacttt acatcataga tcagcacgct gctcaggaac
     4141 gggtcaagta cgaggagtac cgtgaaagca ttggcaatgt tgaccagagc cagcagcaac
     4201 tcctagtgcc ctatatcttt gaatttcctg cggatgatgc cctgcgtctc aaggaaagaa
     4261 tgcctctctt agaggaagtg ggcgtctttc tagcagagta cggagaaaat caatttattc
     4321 tacgtgaaca tcctatttgg atggcagaag aagagattga atcaggcatc tatgagatgt
     4381 gcgacatgct ccttttgacc aaggaagttt ctatcaagaa ataccgagca gagctggcta
     4441 tcatgatgtc ttgcaagcga tctatcaagg ccaatcatcg tattgatgat cattcagcta
     4501 gacaactcct ctatcagctt tctcaatgtg acaatcccta taactgtcct cacggacgtc
     4561 ctgttttggt gcattttacc aagtcggata tggaaaagat gttccgacgt attcaggaaa
     4621 atcacaccag tctccgtgag ttggggaaat attaaaagta taaaaaagtc tgggaaaaat
     4681 tttcaaaatc agaaaaacgc ataaaatcag gtgttcaaaa accttgattt tatgcgtttt
     4741 atcatagaaa tatttacttc attttttcct aattcttttc gaaactcttt ttaaacgacg
     4801 tcagttttat cagtaatctc aaaacagtgt tttgagctaa ttttgccagt tttgtctgta
     4861 acatcgaagt tgtgttttac cactctgcga ctggtttcct agtttgctct atgattttca
     4921 cagagtatta aattgcgatt ttgccaagtt tctttattcg tctaaaagta gagtctgttc
     4981 tatgcgtcta atgtacgaat taggttgacc atttcaatag ctccttgtgc acactcagaa
     5041 cccttatttc ctgctttagt gccagctcgt tctatggctt gttcaattgt atctgtcgtt
     5101 agcacaccaa acataacagg aatttcgcta tttaaactga tttgggcgat tcccttagat
     5161 acctcgctac atacataatc ataatgactt gtattccctc taatgacagc tcccaagcag
     5221 ataattgcat catatttttt actttttgcc atttttgatg caatcagtgg tatttcaaaa
     5281 gctcctggaa tccaggctac cgctatatct ttctcgttta cattctctct tttgagatta
     5341 tctagtgctc cagataataa ttttgaagtt ataaattcat taaatctcgc tacaacaata
     5401 cctattttaa tattgtttgc tactaaatta ccttcataag tgttcattta tttttcctcc
     5461 atatttaaaa tgtgacccat tcgatttttc tttgtttcta aataaaaact atcgtaagga
     5521 ttggcttcta tttcgattga tattctactg gaaatggtaa ttccatattt ttctaactgt
     5581 tcaaccttgt caggattatt tgtcagtaaa tgaagtgact gaagtcccag atctttaagc
     5641 atttgtgctc caatatgata ttctcttaaa tcaccttcaa agcctaatgc aagattggca
     5701 tcaagcgtat ccatgccttg atcttgtaaa tgataggctt ttaatttatt gataagtcca
     5761 attcctcgtc cctcctgtcg caagtaaagt aagacacccg aaccattctc aacaatcatt
     5821 ttcatagctt tatcgaattg ctgtccacaa tcgcaacgta aagagcctaa aacatcccct
     5881 gttaaacatt cggagtggac ccgacataat acattggctt catcctctat gtttcccata
     5941 ataagagcaa gatgatgttc cccatttagt ttatctatat agctaattgc tttgaaatta
     6001 ccgtatctag taggcatatt gacagttgaa actcgttcta ccagctgatc atatactttt
     6061 ctatattctt gtaattcttt gatggtaatt agtggaatgt tgtgtttctt cgagaactga
     6121 attaaatcat ctgttctcat cattttgcca tcatgattca ttatttcaca acataggcca
     6181 cactctttta gtccagctaa ttttaataaa tcaacagttg cttctgtgtg tccatttctt
     6241 tctagaacac cacctttttt tgcaattaaa ggaaacatgt gtcctggcct gcgaaaatca
     6301 gagggtgtta tatcttcagc tacacacata cgtgcggtca gtcctctttc ctcggcagaa
     6361 atacctgtgg tcgtttcttt ataatcaatt gaaactgtaa aagcagtctt atgattatct
     6421 gtattgtttt caaccatagg tgaaagcatt aattgattag ctaaactttc gctcataggc
     6481 atacaaatta atcctttggc ataagtagcc ataaaattaa cattttctgt tgtagctgct
     6541 tgtgcagaac aaattaagtc tccttcattt tctctatcct tgtcgtctat aacaagaaca
     6601 agtcgtccct tctgcaatgc ttctaatgct tcttgtattt ttcgatattc cattgactga
     6661 ttatcctttc tgctaaaatc cattttgata taatagttcc ttagatattt ctgattttgg
     6721 agagttatcc atcagttttt gcacatattt acctaagata tcattttcaa gatttactgt
     6781 actcccgact tgtttactct taagaatggt ttgttccaag gtatgaggga taacagatac
     6841 tgaaaagttt actttggaga ctttagcgac agtcagacta atgccgtcaa ttgtaataga
     6901 tcctttttca actattaaat ctaaaatttc tttttgtgtg ttgatttgat accatacagc
     6961 attatcatct ttttttattg acgagatttt tcctgtacca tcaatgtgtc ctgtaacgac
     7021 gtgaccccca agtcgaccgt tgacagataa ggctctttct agattcacct cacttccatg
     7081 ttttaataga gtaagagctg ttcgactcca tgtttcattc attacatcaa ctgtaaagga
     7141 ttgatggttg aaatgagtaa ctgtaagaca gataccattt actgctatac tatcgcctaa
     7201 atggatatcc gttaatattt ttgaggcttt aattgatagt ttacaattac gagagtcttt
     7261 ctgtattctt tcaacttttc cgatttcttc aattattcct gtgaacatgg ataaatcact
     7321 tcactttcta tgagatagtc atttcctatt tgagaaaaag cataaggttt caatctaata
     7381 gcgtcatttg gcaaagaaat gccttcacct ccgacaggaa acttggcact gcctccaaaa
     7441 atttttggtg caatatatat tttcagctca tcaacaattt gttgttccaa agcactccaa
     7501 ttcattagac tgcccccttc tagaactagg ctatcaatct gcatgtttcc tagatgttgc
     7561 attaaactcg ataagtctat atgattgcct tttttcttta tggaaagtat ttcacagcca
     7621 tgattttgat atagcttcat tttatttttg tcttcagagg aagtggcaat gtaagtttta
     7681 atatcatttg ctgtttttac gattttagag gtaagaggag ttcgtaaatg tgtatcgcat
     7741 atgatacgga taggattttt cccttcctcc aatctacatg tcagcaaagg atcgtcttga
     7801 ataacagtat tgactcccac cataattgca ctaacatagt gtcgtaactg atgcacatgc
     7861 tttcttgctt cttcttcagt aatccatttg gattgatttg ttttagtggc tatttttcca
     7921 tccattgaca ttgcatattt cataaaaaca tagggtacat gctgggtaat atactttcta
     7981 aaacttttta ttaagttaag acactcattt tctaaaattc caacagtaac ttgaagatta
     8041 ttttcctcaa gtatctttac tccttttcca gatacaatag gattacagtc taggcttcca
     8101 atgactactc ttgtaatacc actatcgatt atagcatcta tacagggagg tgttttcccg
     8161 aagtgacaac agggttcaag tgttacataa agcgtcgctc cgacagggga ttctctacag
     8221 tttttaagag catttctctc agcatgtggg ccaccaaaaa actcatgata accttgtccg
     8281 atgatgtgat tatcttttac aataactgcg ccgaccatag gattgggatt gacgtaacca
     8341 gccccttttt gtgccagttt tattgctaat ttcatatatt ttgaatcgct catctcacta
     8401 cctccaaaaa aaatatacct tgaatagggg actactcaag gcatacaaaa gaaaacttat
     8461 gcgattaaca aaaatactct gaaatgacaa gtaatcattt cagagcacgc aaaaagcaca
     8521 aatatacttt tatcttcttt catccagact atactgtcgg ctttggaatt tcaccaaatc
     8581 atgcctttcg gctcgtgggc tataccaccg gtagggaatt acaccctgcc ctgaagatag
     8641 ttattcaatt acagatgatt atagtactta attttgaata tgtcaacaga taaataccga
     8701 ttgtttttga tatactgtat ttgtgataat cgattctcgc tcctcggata aagaaaatat
     8761 gatatactag ataaacgaaa taagagagaa ggaatactat gtacgcatat ttaaaaggaa
     8821 tcattaccaa aattactgcc aaatacattg ttcttgaaac caatggtatt ggttatatcc
     8881 tgcatgtggc caatccttat gcctattcag gtcaggttaa tcaggaggct cagatttatg
     8941 tgcatcaggt tgtgcgtgag gacgcccatt tgctttatgg atttcgctca gaggatgaga
     9001 aaaagctctt tcttagtctg atttcggtct ctgggattgg tcctgtatca gctcttgcta
     9061 ttatcgctgc tgatgacaat gctggcttgg ttcaagccat tgaaaccaag aacatcacct
     9121 acttgaccaa gttccctaaa attggcaaga aaacagccca gcagatggtg ctggacttgg
     9181 aaggcaaggt agtagttgca ggagatggcc ttcctgccaa ggtcgcagtg caagcaagtg
     9241 ctgaaaacca agaattggaa gaagctatgg aagccatgtt ggctctgggc tacaaggcaa
     9301 cagagctcaa gaaaatcaag aaattctttg aaggaacgac agatacagct gagaactata
     9361 tcaagtcggc ccttaaaatg ttggtcaaat aggagcagag aatgacaaaa cgttgttcgt
     9421 gggtcaagat gaccaacccg ctctacatcg cctatcatga tgaggagtgg ggtcagcccc
     9481 tccatgatga ccaagcattg tttgagttgt tgtgtatgga aacctatcag gcaggcctgt
     9541 cttgggaaac ggtactcaac aaacgccaag ctttccgaga agcctttcat agctatcaaa
     9601 ttcactcagt cgcagagatg actgacactg aattggaagc catgctggag aatccagcta
     9661 tcattcgaaa tagagccaag atttttgcta cacgcgctaa cgcccaagcc tttctacagt
     9721 tacaggcaga gtacggctct tttgatgcct atctttggtc ttttgttgag gggaaaactg
     9781 tcgttaacga tgttcctgat tatcgccaag ccccagctaa aacaccctta tctgagaaat
     9841 tagccaaaga tctcaaaaaa cgaggcttca agttcacagg cccagtcgcc gtattgtctt
     9901 ttctacaggc tgcagggcta gttgatgacc acgagaatga ttgtgagtgg aaaggtctta
     9961 aatgatgtct aacaaaaata agggaattct gatttttgcg attctctata cagtcctctt
    10021 tgtgtttgat ggcgttaaat tgctggcttc tttaatgcca tctgccattg caacttatct
    10081 tgtttatgta gttttagctt tatatggctc cttcttgttc aaggatagat tgatccaaca
    10141 atggaaggag attagaaaga ctaaaagaaa attcttcttt ggagtcttaa caggatggct
    10201 ctttctcatt ctgatgactg ttgtctttga atttgtatca gagatgttga agcagtttgt
    10261 gggactagat ggacaaggtc taaatcagtc taatattcaa agtacctttc aagaacaacc
    10321 actactgata gctgtttttg cttgtgtcat tggacctctg gtagaagaat tatttttccg
    10381 tcaggtctta ttgcattact tgcaggaacg gttgccaggt ttactaagca ttattctggt
    10441 aggacttgtt tttgctctga ctcatatgca cagtttggct ctatcagagt ggattggtgc
    10501 agttgattac ttaggtggag gccttgcctt ttctattatt tatgtgaaag aaaaagagaa
    10561 tatctactat cccctacttg ttcacatgtt aagcaacagc ctctccttaa tcattttagc
    10621 tatcagtata gtaaaatgaa ataagaacag gacaaatcaa tcaggacagt caaatcgatt
    10681 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatacact gtaacatgtg
    10741 atgaaaatgc cagtaatgat accgagaaaa aagctgagaa acttttccca gctttatttg
    10801 ttatagtcaa agcgaatgac ttgttcctgt gcatctacat gagcatggac cccaaagggt
    10861 acaattgctc ttggagttgc gtggccgaca ttcagattat agacaatcgg gatattgttg
    10921 tcaatgatat ccaatagtgc ctctttatag tcgtcatgga aagtttcatc cataggtttt
    10981 ccgaccaaga gtccattgat gaccgcgaat atgccagtgt cctttaaagt tagcaacatc
    11041 tttttgaagt cttctggctt aggctcttct tcgcttgttt cgagcaagag gattttccct
    11101 tcccagtctg acaagtcagg gaaaagtttg tatttttggc agagttccgt gctatctgcg
    11161 tatcgagagt tgtcaaagat atcgtagagg gattcgaggc aaccaccgag gattttcccc
    11221 tcgaactgag cacttccttg caacaagtca aaacctgtat ttgtatgact gacacgaggt
    11281 gttcccaggg ccgtgggact aaaatcagtt cgttcctcat accaaacgtc actagggcgg
    11341 atttctgaaa ttcttcccgt ctcaatcaat tctttaaagt agtgaaggct ataggctagc
    11401 atttctttgt ctaattcaca aatgtctgct aaaaaggatt gaccataaaa agtcttgatt
    11461 cctaatttat gcaacatgag gtggttcatg gttgtatccg agaagccaag aaaaattttt
    11521 tgtttgataa ccttttggag ttggtcattt tcaaaaagat aaggtagcaa gcgataggta
    11581 tcgtctccac ctatggcaca taggatcatg tcgatgctat catcagaaaa ggcatgaatc
    11641 aaatcctctg cacgagcttc aggatggtcc ttgataaagt ctaatccttt taacgaatgg
    11701 ggcaaaaaga tgggattgag tcccagaacc ttgagacgtt ggatacccaa gtccacttcg
    11761 tgtttgacaa aatcctctcc gataatgcca ctagataaac taacaatacc aatagtagaa
    11821 accatatctc atcctcctag aaatagattg agcctatttt atcacaaaat ataagagaaa
    11881 gctatgtggg atttcagaag aatactttta atactcttcg aaaatctctt caaaccacgt
    11941 cagttttatc tgcaacctca aagctgtgct ttgagcaacc tgcagctagc ttcctagttt
    12001 gctctttgat tttcattgag tataactcaa aaaagtaagt gaaaaagcaa ccgcacctgc
    12061 agttgctttt atcgttttct tattcttgat agcgtgttgg tcctgcactt gcactacgga
    12121 tattcaagcg tttcttgaga tagaagcgaa gggctaggag agctgctcca ataatagcta
    12181 gtggcaatgg atccagtact gggttaaggc tagctggtag gaagcttgtt gcaaagaaga
    12241 caagcaacca aaggaacata gaagctagga taactagtac agatttccag aaaggtggac
    12301 gttgactgcg atccatatct ggtccatagt attggtaaac aaagtagtac atcaagtaga
    12361 aggcaaatcc accaaccagt ccaactaata gaagagtaat caatccatag ccgaaagctt
    12421 gatctgccgc aaagaaggtt gtgagggcgc tgacaagggc aaagaggcta gtgatgaaaa
    12481 gagctgagtc cataatcatc agttttgggt catcattttc ttttggatgc tctttttcgt
    12541 actgctcttt gacagtgaag ctatgagccc aatgagttgg tgcgccgtat agggaacggg
    12601 cagttgtacc tttagattgc tcctcaagga tttggggaat gacttcctca aaaatagtct
    12661 ggatttcagc gtctgttttc ccatctttga tgaattgttg ggtagcaatg tggacaaact
    12721 cttggttttt cttagttaat ttttgtagat caatttgaga cataggaact cctcttagaa
    12781 ccatttttta tggatgagat agagagtgag cgagacactc atagcaaagg cgataaagac
    12841 gattaaccag aaggcatttg gctctccgtt taggggaatt tcattatcct taaagttcat
    12901 cccgtaggca gaaaagacca tggttgggat ggacatgacg atggtcacaa gggccaaggt
    12961 tttcatgatg ttgttctggt tgttagaaat gatagaggca aaggtctctg tcatagaatg
    13021 caagacgttt ccataaatat ctgccatctc gatggcctgt tgggtttcaa tcagggtgtc
    13081 ttcaagcagg tcttcgtcct caaggtattt cttgatattg ctggttgaac tggtcaattt
    13141 cttaatcacg cgctcatttg ttttgaggga ggccttgaaa tagacgatag ttttttccaa
    13201 ttccatgagc tcaatcaatt cttcattacg agttgattga tgcagttgac tttcgatttg
    13261 ttcactcttg cggtcgattg aacgaagggc tgttaggtaa agctctgcat tgcgataaag
    13321 aatttgaaag ataaaacgtg aacgcatgaa ggtatagaaa ttacgcaatc gacggttgat
    13381 aaagacatca aggacaggta gtggttccaa acacgtagtg ataatggttt cctcagtgat
    13441 gataatacca agcgggatgg ttacgtagta ggtgcggtta tttctttcct ccgtgaccgg
    13501 cacgtctacg ataatcaggg tatactcgtc ttcaatggta atacgagaca tttcttccgc
    13561 atcgagcggt gctcgaaggt cggcaatatc aatatcgaag gtgttggcga tttcgagtga
    13621 ttcattttga gtcggattga cgagattgat ccaagtaccc ggttcaagcg tatcgatctc
    13681 tttaaattca gttgttgtag agagaaaaac ttgtttcata tcccttatcc tttctcattt
    13741 ttcagatttt ttcacactgt actattatac tacaaaatcg gccttttggg taatagaatc
    13801 tcactttttt tggtataatg gtaagcaata atggactaga aagaacaaag atgcaagata
    13861 aaattgtcat tcatggggcg cgtgcccata atttaaaaaa tattgatgtg gagattccgc
    13921 gagacaagtt ggttgtcgtg actggcttgt caggttcagg gaagtccagt ctggcttttg
    13981 atactctcta tgcggaggga caacgtcgct atgtagagag tttgtctgcc tacgctcgtc
    14041 agttcttggg aaatatggaa aaaccagatg tagatgccat tgatggtctc agcccagcta
    14101 tttccatcga ccagaaaacg actagtaaaa atcctcgctc gacggtggga acgacgactg
    14161 aaatcaatga ctatctgcgt ctcctctacg cacgtgtggg gacgccttac tgtatcaacg
    14221 gacatggagc tatcaatgct tcttctgtgg agcaaatcgt tgataaggtt ttggagttac
    14281 ctgaacgcca gcgcttgcag atcttggctc ctgtcatccg caagaaaaaa ggccaacata
    14341 agagtgttat cgagaaggtt cagaaagacg ggtatgttcg tgttcgtgtg gatggggaag
    14401 tctatgatgt gaccgaagtg ccagagttgt ctaagagcaa gcaacacaat atcgatgtcg
    14461 tggttgaccg tattgttatc aaggagggca ttcgtagccg tctctttgat tccattgaag
    14521 ctgcccttcg tatcgcagaa ggttatgtga ttatcgacac catggacgac tctgagttgt
    14581 tgttctctga gcattatgcc tgtccagttt gtggatttac tgtcccagag ttagaacctc
    14641 gtctcttctc tttcaatgct ccctttggct cttgtagtga gtgtgacggc ttggggatca
    14701 agctggaggt agatactgat ttggtagtgc cagatgccag caaaacctta cgtgagggag
    14761 cgctagcacc ttggaatcct atctcatcca actactatcc aaacatgtta gagcaggcca
    14821 tgaaagtctt tggagtggct atggataagc cttttgagga cctgtcagaa gaagataaga
    14881 acttgattct ctatgggtca gatggtaagg aattccattt ccactatgag aatgaatttg
    14941 gtggcgtgcg cgatatcgac attccgtttg agggagttat caataatatc aaacgtcgtt
    15001 accatgaaac caatagcgat tacactcgca ctcagatgcg tctctacatg aatgagctga
    15061 cctgcggaac ctgtcaaggc tatcgtctca atgaccaggc cttgtctgtc cgtgtgggcg
    15121 gccagcaagg gccacatatt ggagaaatct cagacctgtc tatcgctgac cacttggact
    15181 tggtgagcca gttaactttg tctgaaaatg aagccatcat tgctcgtccc attctcaagg
    15241 aaatcaagga tcgtttgacc ttccttaata atgtgggtct taactatcta accctgtcac
    15301 gttcagcagg aaccctttca ggtggggaaa gtcagcgcat tcgtttggca acccagattg
    15361 gttccaacct atcaggcgtc ctctatatcc tagacgagcc gtcaatcggt cttcaccaga
    15421 gggacaatga ccgcctgatt gccagtctga aaaagatgcg tgacttgggc aatactctta
    15481 tcgtggtgga acacgacgaa gataccatgc gtgaagctga ttatctgatt gacgttggtc
    15541 ctggtgccgg tgtttttggt ggtgagattg ttgcagcagg tacacctaag caagtggctc
    15601 gcaacagcaa gtctatcaca ggtcagtact tgtcaggcaa acgtgtcatc ccagtaccag
    15661 aagagcgccg tgtcggaaat ggtcgtttta ttgaagtgac aggagcgcgt gagaacaact
    15721 tgcaaaatgt cacggctcgc tttccactag gaaaatttat cgcagtgaca ggtgtgtcgg
    15781 gttcagggaa atcgactcta atcaacagca ttctcaaaaa agccattgcc cagaagctca
    15841 accgtaattc agacaaacct ggtaagttta agactattac agggattgag catgtcgacc
    15901 gtttgattga tattgaccag agccctatcg gacggacgcc gaggtctaac ccagctacct
    15961 atacaggagt ttttgacgat atacgtgacc tttttgctca gacaaatgaa gccaagattc
    16021 gaggctacaa gaaggggcgc ttcagtttca acgtcaaggg aggtcgctgt gaagcttgct
    16081 caggtgacgg gattatcaag attgagatgc acttcttgcc agatgtttat gtggcttgtg
    16141 aagtttgcca cggaacccgc tataacagtg aaaccctaga agttcactac aaggaaaaga
    16201 atatttcgca ggtcttggat atgacggtca acgatgcggt agaatttttc caacacattc
    16261 cgaaaattca acgcaaactc cagaccatca aggatgtagg gctaggctat gtgaccttgg
    16321 gacagccagc taccaccctt tctgggggag aagcccaacg tatgaagtta gctagcgaac
    16381 tccacaaacg ctcgacagga aaatctttct acattctgga tgagccgacg acagggcttc
    16441 atacagagga cattgctcgc ctgctcaagg ttttagctcg ctttgtagac gatggcaata
    16501 cagtcctcgt catcgagcac aatctggatg ttatcaagac ggcagaccat atcattgact
    16561 tgggacctga gggcggtgtc ggtggtggaa ccatcatcgt aacaggaact ccagaagaag
    16621 tagctgccaa cgaagccagc tatacaggac actatttgaa aggaaagtta catcatgaat
    16681 aaacgcgtac aagcatttct agctaaaatg caagaaaaag aactagatgg tatcatcatc
    16741 aacaatctta aaaacgtcta ttatttgact ggtttttggg gctcaaacgg aacagtcttt
    16801 atcagtcgtg accgtcaggt cttagtgaca gactctcgct atatcatcgc agctaagcaa
    16861 gaaaccagtg gttttgagat tgtggctgat cgtgatgaat tggctgtcat tgcaggaatt
    16921 gttaaggaca tgggcttgac tcgtatcggt tttgaagatg agatttcagt gtcttattac
    16981 caccgtatgc aggcagcttt tgcaggtttg gacttgtttc cgcaaactca gtttgtggaa
    17041 ggtcttcgta tgattaagga tgaggcagag attgcagcga ttcgcaaggc ttgttctatc
    17101 tcagaccaag ctttccgcga tgcgcttgac tttatcaaac caggaaaaac tgaaattgag
    17161 attgccaact tccttgactt ccgcatgcgt gagttgggag catctggctt atcttttgat
    17221 acgatcctag ctagcggtat caattcttct aaaccccatg cccatccaat gcacaaacca
    17281 gtggagttgg gagaagccat taccatggac ttcggctgtc tctatgacca ctatgtcagt
    17341 gatatgaccc ggactatcta tctagggcat gttagcgatg agcaggcaga gatttacaat
    17401 acggttctaa aagctaacca agccttgatt gaccaagcta aggcaggctt aggtttccgt
    17461 gactttgaca aaatccctcg tgatattatc attgaggcag gttatggcga ctactttact
    17521 cacggcattg gccacggtat tggtctggat atccatgagg aaccctactt tagccagact
    17581 tctacagaaa ctattaagac aggtatggcc ttgaccgatg aaccaggtat ctatatcgaa
    17641 ggcaaatatg gcgttcgtat cgaggatgat atcctgatta cagagacagg ttgtgaatta
    17701 ttgaccctag ctccaaaaga gttgatagtc atttagttgt ttgtcaagaa aaaagtacga
    17761 aaatgacgaa aaaagtcaaa aaaaattaaa aataggtcgc aagtcggatg ttttttatgg
    17821 tataatagac taaactgata gtaacatgta gcgaaagggg taggtacatg attaaaattt
    17881 atacagtctc aagttgtact agctgtaaaa aagcaaaaac ctggctcaat gcccaccagt
    17941 taagttataa agaacaaaac cttggtaaag aaggaattac gagagaagaa ttactggata
    18001 ttctaaccaa aacagataac ggaatagcca gcatcgtttc gtctaaaaat cgctatgcca
    18061 aagcccttgg agtggatatt gaagatttga gtgtcaatga agttctcaat ctgattatgg
    18121 aaacaccgag aattttaaag agcccaatcc ttgtagatga aaaacgcctg caagttggct
    18181 acaaggaaga cgatattcgt gccttcctac cacgctctgt ccgtaatgta gaaaatgcag
    18241 aagcacgttt acgtgcagct ctataaacat caaggctggg agcaattccc agtcttattc
    18301 tattttaatt tcaaaaagaa agaagaaaga aatgaaaaaa atagttcttg ttagtctagc
    18361 tttccttttt gtcctggttg gttgcggaca gaaaaaagaa actggaccag ctacaaaaac
    18421 agaaaaggat acgcttcagt cggcattgcc agttattgaa aatgccgaga agaatacagt
    18481 tgtaaccaag actttggtct tgcccaagtc agatgatggt agccagcaaa ctcaaaccat
    18541 tacatacaag gacaagactt ttttgagctt aacgattcaa caaaaacgtc cagtttctga
    18601 tgagttgaag acttatattg accaacatgg agtggaagaa actcaaaaag ctcttcttga
    18661 agcggaggag aaggataagt ctatcattga agctcgtaaa ttggtaggtt tcaaacttga
    18721 aacaaaacta ttgagcgcaa cggaacttca aacaacgact agttttgatt ttcaagttct
    18781 ggatgtcaag aaggcttccc agttggaaca tctgaagaat attggtttgg aaaatctttt
    18841 gaaaaatgaa ccaagcaaat atatttcaga cagattggca aatggtgcga cagaacagta
    18901 gaaaatccaa ataaatagac tgcctgaatt gtagaaggta aggaattatg ctataatggt
    18961 actattctaa ggaaagaggg tgttagaatg ggatttactg aagaaacagt acgttttaaa
    19021 ttggacgatt ccaataaaaa agaaattagc gaaactttga cagatgttta tgcttcgttg
    19081 aacgataagg gttacaaccc aattaaccaa atcgtaggtt acgtattgag tggagaccct
    19141 gcctacgttc ctcgttataa taatgcacga aatcaaatcc gtaagtatga gcgtgatgaa
    19201 atcgttgagg aattggttcg ctactacctc aaaggacaag gagtcgatct ataacctatg
    19261 agaattatgg gattggacgt cggttcaaaa acggtagggg tggcgattag cgatccgctt
    19321 ggttttacag ctcaagggct tgaaatcatc cagataaatg aagaacaagg ccaatttggt
    19381 tttgaccgcg ttaaggaatt ggttgatact tacaaggtgg aacgatttgt agtgggcttg
    19441 cctaaaaaca tgaacaatac aagtggaccg cgcgtagaag ctagtcaagc ctacggagca
    19501 aagctagaag agttttttgg tttaccagta gactatcagg atgaacgctt gacaacagtg
    19561 gctgctgagc gcatgttgat tgaacaagca gatatcagtc gcaataagcg caagaaagtc
    19621 attgataagt tagcagctca gctgatttta caaaattatt tagatagaaa attttaatat
    19681 aaaggagagg ctatgtcaca cgatcataac cacgaccacg aagaacgtga actaatcaca
    19741 ctagtagatg agcaaggaaa tgaaaccttg tttgaaatcc ttttgacaat tgatggaaaa
    19801 gaagaatttg gtaaaaacta tgttcttcta gtaccagtta acgcagaaga agacgaagac
    19861 ggacaagttg aaatccaagc ttactcattc atcgaaaacg aagatggaac agaaggcgaa
    19921 ttgcaaccaa tcccagaaga ctcagaagac gaatggaaca tgattgaaga agtcttcaac
    19981 agctttatgg aggagtgata cagtctggga gactgtatca gcccaactcc cagaaatggg
    20041 gaagagttgg aacgtccagt ggatgttttt agcccagttc ctttaaataa gagagaactg
    20101 gtaggttcgg ggggacgttt ttagcccagc tcctttaaat aagatagagc tggtaagtct
    20161 gggagactgt atcagcccaa ctcccagaaa tggggaagag ttggaacgtc cagtgaacat
    20221 ttttacccca actcttagaa attgagaaga gttggaacat ctagtggatg tttttagccc
    20281 atattcacat tcatagtggc tagttattag ctaaccaggt aagaggtcgg gacgaaaatc
    20341 ctggccttgt ttttattagt aaccatactt taatgcgata attgattgga cttttgtcaa
    20401 ggagatgtgt atgtttgaag tagaagaatg gctccatagt cggattggtt taaattttcg
    20461 atcaggtttg ggccgaatgc agcaagcggt ggatttgtta ggaaatcctg agcagtctta
    20521 ccctattatc cacgtaacag ggactaatgg gaaaggatct accattgctt ttatgaggga
    20581 attatttatg gggcatggca aaaaagttgc gacctttacc tcccctcata tcgtctctat
    20641 caatgaccga atctgcatta atgggcaacc tatagcagac gcagacttta tccgtttggc
    20701 tgatcaggtc aaggagatgg agaaaacgct tctgcaaact cctgaccagt tgtccttttt
    20761 tgaattgctg accttggttg cttttcttta ttttagggag caagaggtgg atttggtttt
    20821 attagaagtg ggaattggtg gcttacttga cacgaccaat gtggtaactg gagagcttgc
    20881 tgtcatcacc tccattgggc ttgaccatca agaaaccttg ggtgatagtc tagaagcaat
    20941 tgcagagcag aaagctggta ttttcaaggc tggtaagaag gcagtgattg cgaaattgcc
    21001 tccagaagct aggcttgtct gtcagaaaaa agccgaatct ttagctgtta acctttatca
    21061 ggcaggtcaa gattttttaa tgctgaatgg tgatttttca agctctttac taaatctttc
    21121 acagctgaac ataggcttag aaggagtcta tcagcaggag aatgcagcct tggcgttgca
    21181 aacttttctt ctttttatgg gagaaggaaa ggaagctgtt gatgaacagg ctgtaagaaa
    21241 ggccttggaa cagacccatt gggctggtcg cttggagcgt attcgcccac agatttactt
    21301 ggatggtgct cataacctcc ctgccttgac tcgcttggtt gagtttatca aagaaaaaga
    21361 gcaggaaggc tatcgacctc aaatcctttt tggagccttg aaacggaagg attatcaagg
    21421 gatgttaggt tacctgactg aaaaattgcc tcaggtggaa ctcaaggtga ccggctttga
    21481 ctatcagggg gctttggacg aaagggatgt gacaggttac gatatagttt cttcttgccg
    21541 agaatttatc agcgattttg aagaaagagc agatgctcag gatttgctgt tcgttacagg
    21601 gtctctctat tttatctcag aagtacgggg ctacctgctg gaccgtgagc agataaattg
    21661 acccccttgt ttgaacttgt tatactaggg gaattgctgg ttagagaaaa tttctctaaa
    21721 ttggtagcag aaaggaaatt catcatgaaa ttaaaaagat tcacactttc tcttgcttct
    21781 ctagcaagtt ttagtctctt agtagcttgt tcacaaagag ctcaacaggt tcaacagcct
    21841 gttgctcagc agcaggtcca acagcctgct caacaacctg ctcaacagaa taccaatact
    21901 gcaaatgcag gaggtaacca aaatcaagcg gctccagtac aaaaccaacc tgttgctcaa
    21961 ccgaccgata ttgatgggac ttatactggt caggatgacg gagaccgtat cactttagtg
    22021 gtaactggaa cgactggtac atggactgag ctcgaatctg acggggatca gaaagtcaaa
    22081 caggttacat ttgattcagc aaatcaacgc atgattattg gcgatgatgt caaaatttac
    22141 actgtaaacg gtaatcaaat cgtcgtagat gatatggata gagacccatc ggaccaaatc
    22201 gttttaacta aataagacta tgcaagtaga aagggctgga tttttcagcc tttttacttt
    22261 tacctagaaa ataatcataa atacttgcct tctaccgaat acctgcgtta tactagtatc
    22321 aattacttgt ttttagcatt caaactatca aggaggggat atgaaatata ggaaatttca
    22381 attattgatg tccaagtatg gctttagtct ttcgattatg ttacttgaac tttgtcttgt
    22441 ttttggtctc tttctttatt taggacgcat ggctcccatt ttatggatta ctgtcctcat
    22501 tctactgagt atcatcacaa tcatttcgat agtcaaccgt aatacgactc ctgagaataa
    22561 ggtaacctgg ttgttagtag cctttgtgcc agtatttggt cccttgctct atctgatgtt
    22621 tggtgaaagg cgattgtcca aaaaagaaat caaacaactg aagaagctag gctctatgca
    22681 tttccaagaa gcaaatagcc agctactaaa agagaaatta aaagaaagtg acaaggcagc
    22741 ttatggagtc atcaagtcct tattgagtat ggataccaat gctgacatct atgatcaaac
    22801 tgcctctaca ttttttccta acggagaagc tatgtggaaa aagatggtag aagatcttaa
    22861 aaaggctgag aaatttattt tcttggaata ttacattata gaagaaggtt tgatgtggaa
    22921 tcgcatacta gatatactag agcaaaaggt agctcagggt gtagaggtta agatgctcta
    22981 tgatgatatc ggctgtatgg ctactttaac aggagattat gcacatcgac ttcgtcagct
    23041 gggcatcgag gcccataaat tcaataaagt tattcctcgt ttgacagtgg cttataataa
    23101 cagagatcat agaaaaatat tgattgttga tggtcagata gcctatactg gtgggatcaa
    23161 tctggcagat gagtacatta accacgtcga gagatttggt tattggaagg atagtggaat
    23221 tcgcttagac ggactagcag taaaagctct gacacgctta tttttgacca cttggtacat
    23281 taatcgagga gaaattagtg attttgatca atatcattta gaaaatcatt ctatcccgag
    23341 tgacggttta accattccat acggaagtgg acccaagcca atttttcgag cgcaggtagg
    23401 gaaaaaagtt tatcagagtt taatcaatca agcaacagaa tcggtctata ttacgacacc
    23461 ttatttgatt atagattatg atttaacaga gacaatcaaa aatgcagcta tgagaggggt
    23521 cgatgttcga attatcaccc cttacatacc agataagaag ttcattcagt tagtcacgag
    23581 aggagcttat cccgaccttc tttctgctgg tgttcggatt tatgagtata gtccaggttt
    23641 tattcatagt aagcagatgt tggtagacga agattttgcg gtggtgggga caatcaatct
    23701 cgactaccgg agcttggtac accattatga aaatgcagtc ttactctata aaactccttc
    23761 tataagggaa atcgcccgag attttcgaaa tatatttgca gattctcagg aagtctatcc
    23821 tcattctatc aaaacgagct ggtatcaaaa gcttgtaaaa gaaatcgccc agctattcgc
    23881 ccctatctta taagaaatct agaacttagg atacaaacca gacctatttt tcttgtcttt
    23941 tacgaataga aagaaagagg aggggaattc atgctaacta aggaagaagt gaatgatatg
    24001 attgagttca aacagacaca tttacaccgc tttcgggaaa ttgaaacctt tgtgaaacta
    24061 tgcaaaaaat cactcaaaca gccatcgcaa gctgacaatc ctaggacttt ttgatatact
    24121 aagacagata aattgaacag gagaaacgat atgagtgtgt atggtagagt agaagaagtt
    24181 cataaggaga atcgtgaacc tctagaatac caaatcgaac aagaatcgca tcatcgtgaa
    24241 tcaagtcgtc ttcctttggt gaaaatttta ctatggagta cgcttgtaac ggggataact
    24301 ctaggagtac cgctattact cgacttaatg agtgcacaag aagtgcagga tttttatgca
    24361 ggttgggcgc ttcatcagac agggaagatt tacagcgact attatggaag tcaaggtttg
    24421 ctttattatt tgctgactta cgtgagtcag ggcggatttt tctttgccat ctttgagtgg
    24481 ttagccttgg tagcaggagg atttttcctt tttagatcag cggacacctt gacagagcaa
    24541 ggagaccaag ctggacatct ggtgactatt ttttacatgc tagttacagg tcttgctttt
    24601 ggtggaggct atgcgactct tttagcgctt cctttcttat tcgcagcctt tagtttagtt
    24661 gcggcttacc taagcaatcc aagccatgat aagggatttg tacggattgg gctagctttg
    24721 gcaggcggat ttttctttgc tcccttatca tcgctcctgt ttattgctgt agtgagttta
    24781 ggcttgttgg tctttaacct tgggcataga cgctttgcgc atgggtttta tcagtttctt
    24841 gcagtggctt taggtttttc acttgtcttt tatccaactg cctactatag tgctgcaaca
    24901 ggaagttttg gggatgcgat tagtggtatt cgttatccta ttgacagtat tcgctttgat
    24961 tttacttcta aaattttaga gaatatgttt ttttatggct tgttgtccct tggtttggga
    25021 tttgtggttt gtatcttttt aggtctcttt caatccaaac cctttaaact atacgtcatt
    25081 tcggttcctg caagtcttgt ggtaatttta ggtttgattt tacttttctt ttcacaagag
    25141 cctctgcacg cttcttattt gatggtcgtc ttccctgttt tcctactttt attggtaacc
    25201 aatattaaga gtcaacagag ggggcgtagt gctagaagaa gccgaagaga aacgccagtt
    25261 agcctatgga gtcgtttctt caaaggaaat ctatatctgc tagtttttga gtttgtctat
    25321 cttttgtctg ttcctttttt gatgaagttt gtcctttatc cagtacctta tcaagaacgt
    25381 aatcgtcttg ctgatttggt aaaagaggag acaaatacgg aagatgctat ctatgcatgg
    25441 gatgatactg cgactcttta tcgtaagagt gagcgcttgt cgccatcggc gattttgtcc
    25501 ccgttgcact atacagcaac tgaggaaaat cgtaataagt tacttaatga cttgaaagaa
    25561 aaacaaccta aggtgattgt ggtaaatgat aaggtggtag tctggtctga agtggaaaca
    25621 ctcttaaaag aaaattacca acaagtaaag actgattact cagagtttaa agtctataaa
    25681 attaaataac caaatcaata tcttgtgtat ttttaaaaat tttaggattt ttaacacaag
    25741 atattgattt ttctttttag agtggtataa tactttttag aaagaacatt ttagaaaaga
    25801 gcatgcatat gattgcacta gaagaaaaaa ttacaatttt gccaactctc ttcgtcgaga
    25861 aacgagatgg gagacgtgtt gtatttgatg tggacaagat tgacaaggct ctccacaagg
    25921 cggctgacaa ggttatggat gtgacacccc tggttgaaaa acgcctcaat gatctgactg
    25981 agcgaattat tacagaaatt catagtcgct ttccacaggg aattaagatt tacgaaattc
    26041 aaaatatcgt agaacatgaa ctccttgaag ccaaagaata tgcgctggct gaggagtata
    26101 ttacttatcg gacacagagg gattttgagc gctcaaaagc gacggatatc aactttagta
    26161 ttcataaact tctcaacaaa gaccagacag ttgtcaatga aaacgctaat aaagacagtg
    26221 atgtctttaa cactcagcgt gatttgacag cagggattgt tgggaaatca atcggactgc
    26281 aaatgcttcc taagcacgta gccaatgccc accaaaaggg ggatatccac tatcacgatt
    26341 tggactacag tccctatacc cctatgacca actgctgttt gattgatttt aagggtatgt
    26401 tggaaaatgg ttttaagatt ggaaatgcag aggtagagag tcccaagtct atccagactg
    26461 cgacagcaca gatttctcaa atcattgcca acgttgcttc tagccagtac ggtggctgtt
    26521 cagctgaccg tatcgatgaa attttggcgc cttatgcaga gaagaattat caaaaacatc
    26581 tcaaagatgc agaagagtgg gtattgcctg aaaaacggga agattacgct tggaagaaaa
    26641 cgcaaaagga catctacgat gccatgcaat ctcttgagta tgaaatcaat actctcttca
    26701 cttcaaatgg acaaacacct tttacttcgt taggttttgg tctgggaacc agtcgttttg
    26761 aacgagaaat tcaaaaagct attttaaaca ttcgcatcaa gggtcttggt tcagaacacc
    26821 gtacggctat ctttcctaaa cttattttca ctctgaaaag aggccttaat ttagaggaag
    26881 gaactcccaa ctacgacatc aagcagttgg ctcttgagtg tgcaaccaaa cggatgtatc
    26941 cagatgtttt atcttacgat aagattgttg acttgacagg atccttcaag gtgcctatgg
    27001 gttgccgttc tttcctccaa ggatggaagg atgaaaatgg tgtagaagtc aattcaggtc
    27061 gcatgaatct gggtgttgtg acggttaatc tgcctcgtat tgctcttgag tctgaaggtg
    27121 atatgaataa gttctgggaa atcttcaacg agcgaatgaa tatcgcagaa gatgctcttg
    27181 tttaccgtgt cgaacgcact aaagaggcga caccagcaaa tgctcctatt ctttatcagt
    27241 acggtgcttt tggccatcgt ctaggtaaag aagaaagtgt tgaccagctc tttaagaatc
    27301 gtcgtgctac cgtttcgctg ggctatatcg gcttgtatga agtagcgaca gttttctttg
    27361 gtaacagctg ggaaagtaat ccagatgcta aggaattcac gctagacatc attcacgata
    27421 tgaaacgccg tgtagaagag tggtcagacc aatatggcta ccatttctct atctactcaa
    27481 caccatccga aagtctgaca gaccgtttct gccgactaga tatagacaag tttggctcta
    27541 ttcctgatat cacagacaag gaatactaca ccaactcttt ccactacgat gttcgtaaaa
    27601 atccaacacc gtttgaaaaa ttggactttg agaaagtcta tccagaagca ggtgcgtcag
    27661 gtggtttcat ccattattgt gagtatccag tccttcagca aaatccaaag gccttggaag
    27721 ctgtctggga ttatgcttat gaccgtgtag gctatctagg caccaatact ccgattgacc
    27781 gttgctacaa gtgtgacttt gaaggggatt ttgaaccaac tgagagaggg tttgcttgtc
    27841 caaactgtgg caatagcgac cctaaaacag tagatgtggt gaagcgaact tgtggctacc
    27901 taggtaatcc tcaagcaaga ccgatggtca acgggcgtca caaggaaatc gctgcgcgtg
    27961 tcaaacatat gaatggttca acgattaaaa tagctgggca tcaagtaaca aattagaaag
    28021 aaatgaaatg ggaaaatatc aactagacga taaggggcgc gcacaagtga cccgttatca
    28081 cgagaaacac tctaaaggtg gagctggtaa gaaagaacgc ttgcttagct tcagagaaca
    28141 atttttaaac aagaacaaga aaaaataaaa gtgagagcca gctctcgctt ttctcatagt
    28201 gggaggtaag gatggaatta cgcagaccaa gattagcgga taagaaagct gttttagata
    28261 tgatgacaga gtttgaaaag agtcaatcag cccatgatgg aggattttgg gatgttgagg
    28321 atttttctta cgaggagtgg ctagaaggta accgtaataa agaaatggga atatggctac
    28381 ctgaaaatcg cgttccatcg atacagttcg tattgtttgg tgaatcaggt tgtgctctag
    28441 gatttttgaa tctgcgattg agactgaatg aggggttact gaattatgct ggccacattg
    28501 gctactccat ccgtccatct gaaagaggca agggttatgc aaaagagact ctccgtcagg
    28561 gcttgcaagt tgctaaggaa aagaacatca agaaagctct ggtgacctgt agcgtgaata
    28621 atcttgctag cagagcagtc attctagcaa atggtggaat atttgaggat gctcgcaatg
    28681 gagtcgagcg ttattggata gaggtagcga atgaataatc caaaaccaca agaatggaaa
    28741 agcgaggaac ttagtcaagg tcgtatcatt gactacaagg cctttaactt tgtggacggc
    28801 gaaggcgtgc gtaactctct ctatgtatca ggctgtatgt ttcactgcga gggatgttat
    28861 aatgttgcga cttggtcttt taatgctggc attccctata cagcagaatt agaagagcag
    28921 atcatggcag atcttgctca gccctatgtt caaggtttga ctttgttggg aggggagcct
    28981 tttcttaata ctgggattct cttgccactt gttaagcgga ttcggaagga attgccagac
    29041 aaggacatct ggtcctggac cggctacact tgggaagaaa tgatgttgga aactccagat
    29101 aaactggaat tcttgtcact gattgacatt cttgtcgatg gaagatatga tcgaactaag
    29161 agaaatctta tgctccagtt tcgaggttcg tctaaccaac gaattatcga tgtgcaaaaa
    29221 tcgctcaaaa gtgggcaagt agtgatttgg gacaagctca atgacggaaa agaaagctat
    29281 gaacaggtga agagagaatg aagaaaaaag acttagtaga ccaactagtc tcagagatcg
    29341 agacggggaa agtcaggaca ctgggaatat acggtcatgg agcttcaggt aaatcaacct
    29401 ttgcacagga attgtaccaa gctttagatt ctactacagt aaatttgcta gagacagatc
    29461 cttatatcac ctcaggacgc catctggtag tacccaagga cgcgccgaat caaaaggtga
    29521 cagccagtct gccagtggcg catgaactgg agagtttgca gagagatatc cttgccttgc
    29581 aggcgagtat ggatgtcttg acaattgaag aaccttggaa ggctagtgag gtcttgtctg
    29641 gagccaaacc aattttgatt gtcgaaggga tgtctgttgg ctttctaccc aaggaactct
    29701 ttgaaaaaac catctgtttc tacacggatg aggagaccga attaaagcga cgccttgcta
    29761 gagatacgac tgtgagaaat cgcgatgcat cctttatatt ggctagccat cagatgagac
    29821 gggagcagta tctgcgatac tataaagaaa ctgagtctaa ggcggatatc ttagtggacc
    29881 aatcagaaga taaatttgat gtcaagagga cttaacttat gtatagaaga aatatagaag
    29941 aaaatcccta attttagaaa gaaaaagtag gaaaacagtt tcatccccaa aaaacgaaaa
    30001 aacctaacaa atcccttgca atcgcagggg atttgtgtta ttctattatg gtgctgtaaa
    30061 ttacagcctt agttttgatg caagaggttg cgacacgctc ggttgcattg ccacgcaaca
    30121 ccgcgtcggt tttcttgtgg agctagccta ttatcttaaa tagacgaaaa ggagaaaaag
    30181 atggcaaaca aaaaaatccg tatccgtttg aaagcttacg aacaccgtac gcttgacaca
    30241 gcggctgcaa aaatcgtaga atcagctact cgtacaggtg cacaagttgc gggtccaatc
    30301 ccacttccaa ctgaacgtag cctctacaca atcattcgtg cgactcacaa atacaaagac
    30361 tctcgcgaac aatttgaaat gcgtacacac aaacgtttga tcgatatcgt taacccaact
    30421 caaaaaacag ttgatgcctt gatgaaattg gatcttccaa gtggtgtaaa cgtagaaatc
    30481 aaactttaat ctaaaatata aaagagcaga ggctggtgtt tcaatctaat tgaacacggg
    30541 ctaaactcgg tgtgaaaaag ataaacttcc tcgcgtctgc tagacactgt gtcagtttcc
    30601 tattttcact ttgagtttga cgccctttgt atcttagact tgagcataaa aaacgctcgt
    30661 taaaaacttt ttgaataaaa aatatagaaa aggaactatt ttctcatgac aaaaggaatc
    30721 ttagggaaaa aagtgggaat gactcaaatc ttcactgaag ctggcgaatt gatccctgta
    30781 acagttattg aagcaactcc aaacgttgtt cttcaagtta aaactgttga aacagacgga
    30841 tacaacgcta tccaagttgg tttcgatgac aaacgcgaag tattgagcaa caaacctgct
    30901 aaaggacatg tagcgaaagc taacacggct cctaagcgct tcattcgtga attcaaaaac
    30961 gttgaaggct tggaagttgg tgctgaaatt acagttgaaa cattcgcagc tggagacgtt
    31021 gttgacgtaa ctggtacttc taaaggtaaa ggtttccaag gtgttatcaa acgccacgga
    31081 caatcacgtg gaccaatggc tcacggttct cgttaccacc gtcgtccagg ttctatggga
    31141 cctgttgcac ctaaccgcgt attcaaaggt aaaaaccttg caggacgtat gggtggtgac
    31201 cgcgtaacaa ttcaaaatct tgaagttgta caagttgttc cagaaaagaa cgttatcctt
    31261 atcaaaggta acgtaccagg tgctaagaaa tctcttatca ctatcaaatc agcagttaaa
    31321 gctggtaaat aataaagaaa ggggaaatca gtcacaatgg caaacgtaac attatttgac
    31381 caaactggta aagaagctgg ccaagttgtt cttagcgatg cagtatttgg tatcgaacca
    31441 aatgaatcag ttgtgtttga tgtaatcatc agccaacgcg caagccttcg tcaaggaaca
    31501 cacgctgtta aaaaccgctc tgcagtatca ggtggtggac gcaaaccatg gcgtcaaaaa
    31561 ggaactggac gtgctcgtca aggttctatc cgctcaccac aatggcgtgg tggtggtgtt
    31621 gtcttcggac caactccacg ttcatacggc tacaaacttc cacaaaaagt tcgtcgccta
    31681 gctcttaaat cagtttactc tgaaaaagtt gctgaaaaca aattcgtagc tgtagacgct
    31741 ctttcattta cagctccaaa aactgctgaa tttgcaaaag ttcttgcagc attgagcatc
    31801 gattctaaag ttcttgttat ccttgaagaa ggaaatgaat tcgcagctct ttcagctcgt
    31861 aaccttccaa acgtgaaagt tgcaactgct acaactgcaa gtgttcttga catcgcaaat
    31921 agcgacaaac ttcttgtcac acaagcagct atctctaaaa tcgaggaggt tcttgcataa
    31981 tgaatttgta tgatgttatc aaaaaacctg tcatcactga aagctcaatg gctcaacttg
    32041 aagcagggaa atatgtattt gaagttgaca ctcgtgcaca caaacttttg atcaagcaag
    32101 ctgttgaagc tgctttcgaa ggtgttaaag ttgccaatgt taacacaatc aacgtaaaac
    32161 caaaagctaa acgtgttgga cgttacactg gttttactaa caaaactaaa aaagctatca
    32221 tcacacttac agctgattct aaagcaatcg agttgtttgc tgctgaagct gaataatcta
    32281 aggaggaaat atcgtgggaa ttcgtgttta taaaccaaca acaaacggtc gccgtaatat
    32341 gacttctttg gatttcgctg aaatcacaac aagcactcct gaaaaatcat tgcttgttgc
    32401 attgaagagc aaggctggtc gtaacaacaa cggtcgtatc acagttcgtc accaaggtgg
    32461 tggacacaaa cgtttctacc gtttggttga cttcaaacgt aataaagaca acgttgaagc
    32521 agttgttaaa acaatcgagt acgatccaaa ccgttctgca aacatcgctc ttgtacacta
    32581 cactgacggt gtgaaagcat acatcatcgc tccaaaaggt cttgaagtag gtcaacgtat
    32641 cgtttcaggt ccagaagcag atatcaaagt cggaaacgct cttccacttg ctaacatccc
    32701 agttggtact ttgattcaca acatcgagtt gaaaccaggt cgtggtggtg aattggtacg
    32761 tgctgctggt gcatctgctc aagtattggg ttctgaaggt aaatacgttc ttgttcgtct
    32821 tcaatcaggt gaagttcgta tgattcttgg aacttgccgt gctacagttg gtgttgtcgg
    32881 aaacgaacaa catggacttg taaaccttgg taaagcagga cgtagccgtt ggaaaggtat
    32941 ccgcccaaca gttcgtggtt ctgtaatgaa ccctaacgat cacccacacg gtggtggtga
    33001 aggtaaggca ccagttggtc gtaaagcacc atctactcca tggggcaaac ctgctcttgg
    33061 tcttaaaact cgtaacaaga aagcgaaatc tgacaaactt atcgttcgtc gtcgcaacga
    33121 gaaataatat taaactagtc gcttaagcaa ctagtaaatc cgccagctcg gtagcgctcc
    33181 ataggagtgc aagccgctgt ggtacaacat ttaaaggaga aaatataaaa atgggacgca
    33241 gtcttaaaaa aggacctttc gtcgatgagc atttgatgaa aaaagttgaa gctcaagcta
    33301 acgacgaaaa gaaaaaagtt attaaaactt ggtcacgtcg atcaacgatc ttcccaagtt
    33361 tcattggtta cactattgca gtttatgacg gacgtaaaca cgtacctgtt tacatccaag
    33421 aagacatggt aggccacaaa cttggtgaat ttgcaccaac tcgtacttac aaaggtcacg
    33481 ctgcagacga caagaaaaca cgtagaaaat aaggagaaca taaatggcag aaattacttc
    33541 agctaaagca atggctcgta cagtacgtgt ttcacctcgt aaatcacgtc ttgttcttga
    33601 taacatccgt ggtaaaagcg tagccgatgc aatcgcaatc ttgacattca ctccaaacaa
    33661 agctgctgaa atcatcttga aagttttgaa ctcagctgta gctaacgctg aaaacaactt
    33721 tggtttggat aaagctaact tggtagtatc tgaagcattc gcaaacgaag gaccaactat
    33781 gaaacgtttc cgtccacgtg cgaaaggttc agcttcacca atcaacaaac gtacagctca
    33841 catcactgta gctgttgcag aaaaataagg aggtaaaatc gtgggtcaaa aagtacatcc
    33901 aattggtatg cgtgtcggca tcatccgtga ttgggatgcc aaatggtatg ctgaaaaaga
    33961 atacgcggat taccttcatg aagatcttgc aatccgtaaa ttcgttcaaa aagaacttgc
    34021 tgacgcagca gtttcaacta ttgaaatcga acgcgcagta aacaaagtta acgtttcact
    34081 tcacactgct aaaccaggta tggttatcgg taaaggtggt gctaacgttg atgcactccg
    34141 tgcaaaactt aacaaattga ctggaaaaca agtacacatc aacatcatcg aaatcaaaca
    34201 acctgatttg gatgctcacc ttgtaggtga aggaattgct cgtcaattgg agcaacgtgt
    34261 tgctttccgt cgtgcacaaa aacaagcaat ccaacgtgca atgcgtgctg gagctaaagg
    34321 aatcaaaact caagtatcag gtcgtttgaa cggtgcagat atcgcccgtg ctgaaggata
    34381 ctctgaagga actgttccgc ttcacacact tcgtgcagat atcgattacg cttgggaaga
    34441 agcagatact acatatggta aacttggtgt taaagtatgg atctaccgtg gtgaagttct
    34501 tccagctcgt aaaaacacta aaggaggtaa ataaccaatg ttagtaccta aacgtgttaa
    34561 acaccgtcgt gaattccgtg gaaaaatgcg cggtgaagca aaaggtggaa aagaagtagc
    34621 attcggtgaa tacggtcttc aagctacaac tagccactgg atcactaacc gccaaatcga
    34681 agctgctcgt atcgccatga ctcgttacat gaaacgtggt ggtaaagttt ggattaaaat
    34741 cttcccacac aaatcataca ctgctaaagc tatcggtgtg cgtatgggat ctggtaaagg
    34801 ggcacctgaa ggttgggtag caccagttaa acgtggtaaa gtgatgttcg aaatcgctgg
    34861 tgtatctgaa gagattgcac gtgaagcgct tcgacttgct agccacaaat tgccagttaa
    34921 atgtaaattc gtaaaacgtg aagcagaata aggagaaggc atgaaactta atgaagtaaa
    34981 agaatttgtt aaagaacttc gtggtctttc tcaagaagaa ctcgcgaagc gcgaaaacga
    35041 attgaaaaaa gaattgtttg aacttcgttt ccaagctgct actggtcaat tggaacaaac
    35101 agctcgcttg aaagaagtta aaaaacaaat cgctcgtatc aaaacagttc aatctgaagc
    35161 gaaataatag actagggaag gagaaatttc aatggaacgc aataatcgta aagttcttgt
    35221 tggacgtgtt gtatctgaca aaatggacaa gacaatcaca gttgtagttg aaacaaaacg
    35281 taaccaccca gtctatggta aacgtattaa ctactctaaa aaatacaaag ctcatgatga
    35341 aaacaatgtt gccaaagaag gcgatatcgt acgtatcatg gaaactcgcc cgctttcagc
    35401 tacaaaacgt ttccgtcttg tagaagttgt tgaagaagcg gtcatcatct aatcaaacct
    35461 gaaaggagaa aactgaaatg attcaaacag aaactcgttt gaaagtcgca gacaacagcg
    35521 gtgctcgcga aatcttgact atcaaagttc ttggtggttc aggacgtaaa tttgcaaaca
    35581 tcggtgatgt tatcgtggca tctgtaaaac aagctactcc tggtggtgcg gttaaaaaag
    35641 gtgacgttgt taaagcagtt atcgttcgta ctaaatcagg tgctcgtcgt gctgatggtt
    35701 catacatcaa atttgacgaa aacgcagcag ttatcatccg tgaagacaaa actcctcgcg
    35761 gaacacgtat ctttggccca gttgcacgtg aattgcgtga aggtggcttc atgaagatcg
    35821 tgtcacttgc tccagaagta ctttaatttt taggaacaaa ctagtcccct agcttcaagc
    35881 tagggtgccc ttatgggcgt aagaaaaatc aaggagaaac ctaatgtttg taaaaaaagg
    35941 cgacaaagtt cgcgtaatcg ctggtaaaga taagggaaca gaagctgttg tccttactgc
    36001 ccttccaaaa gtaaacaaag ttatcgttga aggtgttaac attgttaaga aacaccaacg
    36061 tccaactaac gagcttcctc aaggtggtat catcgagaaa gaagcagcta tccacgtatc
    36121 aaatgttcaa gttttggata aaaatggtgt agctggtcgt gttggttaca aatttgtaga
    36181 cggtaaaaaa gttcgctaca acaaaaaatc aggcgaagtg cttgattaat cacgaaggaa
    36241 aggagaagta taatggcaaa tcgtttaaaa gaaaaatatc ttaatgaagt agttcctgct
    36301 ttgacagaac aattcaacta ctcatcagtg atggctgtgc ctaaagtaga taagattgtt
    36361 ttgaacatgg gtgttggtga agctgtatca aacgctaaaa gccttgaaaa agctgctgaa
    36421 gaattggcac ttatctcagg tcaaaaacca cttatcacta aagctaaaaa atcaatcgcc
    36481 ggcttccgtc ttcgtgaagg tgttgcgatc ggtgcaaaag ttacccttcg tggtgaacgt
    36541 atgtacgaat tcttggataa attggtatca gtttcacttc cacgtgtacg tgacttccac
    36601 ggtgtcccaa caaaatcatt tgatggacgc gggaactaca cacttggtgt gaaagaacaa
    36661 ttaatcttcc cagaaatcaa cttcgatgac gttgacaaaa ctcgtggtct tgacatcgtt
    36721 atcgtaacaa ctgctaacac tgacgaagag tcacgtgcat tgcttacagg ccttggaatg
    36781 ccttttgcaa aataatatag gaggtaaatc taatggctaa aaaatcaatg gtagctagag
    36841 aggctaaacg ccaaaaaatt gttgaccgtt atgctgaaaa acgtgctgca ttaaaggcgg
    36901 caggggacta cgaaggttta tctaaattac ctcgcaacgc ctcaccgact cgtttacata
    36961 atcgttgtag ggttacgggg cgcccacatt cagtttaccg caaatttggt ctgagtcgta
    37021 tcgcttttcg cgaacttgcg cataaaggtc aaattcctgg tgtaacaaaa gcatcttggt
    37081 aatttaagat atcaagagtg tcaaaactcc aagtaaaaat aggaaacttg acgaagaaac
    37141 taaagtttct aggaaagttt atctttttca cacagagttt agcccgggtt caattgggct
    37201 tgccaatttg aacacgagct acagctttgg caaaaaagac caatttgctt tggagcattg
    37261 cttctgcatt aaattgtcta tttttgctcg tgctgttacg ctctttgtat catgtattaa
    37321 ctagcaagtg caacttgcaa actactagta agaggagaaa aacaaaatgg ttatgactga
    37381 cccaatcgca gacttcctaa ctcgtattcg taatgctaac caagctaaac acgaagtact
    37441 tgaagtacct gcatcaaaca tcaaaaaagg gattgctgaa atccttaaac gcgaaggttt
    37501 tgtaaaaaac gttgaaatca ttgaagatga caaacaaggc gtcatccgtg tatttcttaa
    37561 atacggacca aatggtgaga aagttatcac taacttgaaa cgtgtttcta aaccaggact
    37621 tcgtgtctac aaaaaacgtg aagaccttcc aaaagttctt aacggacttg gaattgccat
    37681 cctttcaact tctgaaggtt tgcttactga taaagaagca cgccaaaaga atgttggtgg
    37741 tgaggttatc gcttacgttt ggtaaaatca agatacaaag ctcgtaaaga acaaagcaaa
    37801 attaggaagt tggagaagtt tgtttacaaa caagccaact tatctatttt gcacagttct
    37861 tagagcgtgt tcagttcagc tcttgaacta aataagtatc tgaaccccgt gaaaactggc
    37921 cgttctggcc tgacaattta acaggagaaa ataaacatgt cacgtattgg taataaagtt
    37981 atcgtgttgc ctgctggtgt tgaactcgct aacaatgaca acgttgtaac tgtaaaagga
    38041 cctaaaggag aacttactcg tgagttctca aaagatattg aaatccgtgt ggaaggtact
    38101 gaaataactc ttcaccgtcc aaacgattca aaagaaatga aaactatcca cggaactact
    38161 cgtgcccttt tgaacaacat ggttgttggt gtatcagaag gattcaagaa agaacttgaa
    38221 atgcgtgggg ttggttaccg tgcacagctt caaggatcta aacttgtttt ggctgttggt
    38281 aaatctcatc cagacgaagt tgaagctcca gaaggaatta cttttgaact tccaaaccca
    38341 acaacaatcg ttgttagcgg aatttcaaaa gaagtagttg gtcaaacagc tgcttacgta
    38401 cgtagccttc gttcaccaga accatataaa ggtaaaggta tccgttacgt tggtgaattc
    38461 gttcgccgta aagaaggtaa aacaggtaaa taatgttgag tggttgatca tcaaccacca
    38521 acctattttc caactttgtg catagcacac gatttaaaac taaagaggtg aaaactgtga
    38581 tttcaaaacc agataaaaac aaactccgcc aaaaacgcca ccgtcgcgtt cgcggaaaac
    38641 tctctggaac tgctgatcgc ccacgtttga acgtattccg ttctaataca ggcatctacg
    38701 ctcaagtgat tgatgacgta gcgggtgtaa cgctcgcaag tgcttcaact cttgataaag
    38761 aagtttcaaa aggaactaaa actgaacaag ccgttgctgt cggtaaactc gttgcagaac
    38821 gtgcaaacgc taaaggtatt tcagaagtgg tgttcgaccg cggtggatat ctatatcacg
    38881 gacgtgtgaa agctttggct gatgcagctc gtgaaaacgg attgaaattc taataggagg
    38941 acactagaaa atggcattta aagacaatgc agttgaatta gaagaacgcg tagttgctgt
    39001 caaccgtgtt acaaaagttg ttaaaggtgg acgtcgtctt cgtttcgcag ctcttgttgt
    39061 tgttggtgac cacaatggtc gcgtaggatt tggtactggt aaagctcaag aagttccaga
    39121 agcaatccgt aaagcagtag atgatgctaa gaaaaacttg atcgaagttc ctatggttgg
    39181 aacaacaatc ccacacgaag ttctttcaga attcggtgga gctaaagtat tgttgaaacc
    39241 tgctgtagaa ggttctggag ttgccgctgg tggtgcagtt cgtgccgttg tggaattggc
    39301 aggtgtggca gatattacat ctaaatcact tggttctaac actccaatca acattgttcg
    39361 tgcaactgtt gaaggtttga aacaattgaa acgcgctgaa gaaattgctg cccttcgtgg
    39421 tatttcagtt tctgatttgg cataagaaag gggataaaat ggctcaaatt aaaattactt
    39481 tgactaagtc tccaatcgga cgcattccat cacaacgtaa aactgttgta gcacttggac
    39541 ttggcaaatt gaacagctct gttattaaag aagataacgc tgctatccgt ggtatgatca
    39601 cagcagtatc tcacttagta acagttgaag aagtaaacta atgaagtttt aggggatgtg
    39661 cactgtacca tcccctaaaa ctagatatag tcatctatga tgacatcgta taggcgagtt
    39721 gatgggggag acaacctttt ctcccttatc ggcgctagca ttttacaaaa gaggagaaaa
    39781 taaaaatgaa acttcatgaa ttgaaacctg cagaaggttc tcgtaaagta cgtaaccgcg
    39841 ttggtcgtgg tacttcatca ggtaacggta aaacatctgg tcgtggtcaa aaaggtcaaa
    39901 aagctcgtag cggtggcgga gttcgccttg gttttgaagg tggacaaact ccattgttcc
    39961 gtcgtcttcc aaaacgtgga ttcactaaca tcaacgctaa agaatacgca attgtgaacc
    40021 ttgaccaatt gaacgtcttt gaagatggtg ctgaagtaac tccagttgtt cttatcgaag
    40081 caggaattgt taaagctgaa aagtcaggta ttaaaattct tggtaacggt gagttgacta
    40141 agaaattgac tgtgaaagca gctaaattct ctaaatcagc tgaagaagct atcactgcta
    40201 aaggtggttc agtagaagtc atctaagaga ggtgacctat gttttttaaa ttattaagag
    40261 aagctcttaa agtcaagcag gttcgatcaa aaattttatt tacaattttt atcgttttgg
    40321 tctttcgtat cggaactagc attacagttc ctggtgtgaa tgccaatagc ttgaatgctt
    40381 taagtggatt atccttctta aacatgttga gcttggtgtc ggggaatgcc ctaaaaaact
    40441 tttcgatttt tgccctagga gttagtccct atatcactgc ttctattgtt gtccaactct
    40501 tgcaaatgga tattttaccc aagtttgtag agtggggtaa acaaggggaa gtaggtcgaa
    40561 gaaaattgaa tcaagctact cgttatattg ctctagttct cgcttttgtg caatctatcg
    40621 ggattacagc tggttttaat accttggctg gagctcaatt gattaaaact gctttaactc
    40681 cacaagtttt tctgacgatt ggtatcatct taacagctgg tagtatgatt gtcacttggt
    40741 tgggtgagca aattacagat aagggatacg gaaacggtgt ttccatgatt atctttgccg
    40801 ggattgtttc ctcaattcca gagatgattc agggcatcta tgtggactac tttgtgaacg
    40861 tcccaagtag ccgtatcact tcatctatca ttttcgtaat cattttgatt attactgtat
    40921 tgttgattat ttactttaca acttatgttc aacaagcaga atacaaaatt ccaatccaat
    40981 atactaaggt tgcacaaggt gctccatcta gctcttacct tccgttaaag gtaaatcctg
    41041 ctggagttat ccctgttatc tttgccagtt cgattactgc agcgcctgcg gctattcttc
    41101 agtttttgag tgccacaggt catgattggg cttgggtaag ggtagcacaa gagatgttgg
    41161 caactacttc tccaactggt attgccatgt atgctttgtt gattattctc tttacattct
    41221 tctatacgtt tgtacagatt aatcctgaaa aagcagcaga gagcctacaa aagagtggtg
    41281 cctatatcca tggagttcgt cctggtaaag gtacagaaga atatatgtct aaacttcttc
    41341 gtcgtcttgc aactgttggt tccctcttcc ttggtgtgat ttccatttta ccgattgcag
    41401 ctaaagatgt atttggtctt tctgatgttg ttgcctttgg tggaacaagt ctcttgatca
    41461 ttatctctac aggtatcgaa ggaatcaagc aattggaagg ttacctattg aaacgtaagt
    41521 atgttggttt catggacaga acagaataaa agtatttact gaatcagtaa atgctgaggg
    41581 agtggaggtt taaactctga catttgtaag agttggatct cccctcttct attttgtttt
    41641 taaatagggg tgaaaagact ttttgcttct atttaaaaat aaaataagga gatcaaatca
    41701 tgaatctttt gattatgggc ttacctggtg caggtaaggg aactcaagca gcaaaaatcg
    41761 tagaacaatt ccatgttgca catatctcaa caggtgatat gttccgcgct gcaatggcaa
    41821 atcaaactga aatgggtgtt cttgctaagt catatattga caagggtgaa ttggttcctg
    41881 acgaagttac aaatggaatc gtaaaagaac gcctttcaca agatgatatt aaagaaacag
    41941 gattcttatt ggatggttac ccacgtacaa ttgaacaagc tcatgccttg gacaaaacat
    42001 tggctgaact tggcattgaa ctagaaggtg ttatcaatat tgaagtgaac cctgacagcc
    42061 tcttggaacg tttgagtggc cgtatcatcc accgcgtaac tggagaaact ttccacaagg
    42121 tctttaaccc accagttgac tataaagaag aagattacta ccaacgtgaa gatgataagc
    42181 ctgagacagt aaaacgtcgt ttggatgtta atattgctca aggagaacca atcattgctc
    42241 actaccgtgc caaaggtttg gttcatgaca tcgaaggtaa tcaagatatc aatgatgtct
    42301 tctcagatat tgaaaaagta ttgacaaatt tgaaataaag cgtttttcat acttgcaaaa
    42361 attcgctaca aatgttatac tgagatagtc tgacttataa ttgttgtctc tgtgtctaga
    42421 ggcatcgaat cgaaatttat ggaggtgctt ttgcgtggca aaagacgatg tgattgaagt
    42481 tgaaggcaaa gtagttgata caatgccgaa tgcaatgttt acggttgaac ttgaaaatgg
    42541 acatcagatt ttagcaacag tttctggtaa aattcgtaaa aactatattc gtattttagc
    42601 gggagatcgt gttactgtcg aaatgagtcc atatgacttg acacgtggac gtatcactta
    42661 ccgctttaaa taatcgaaaa acttggaggg ataagaaatg aaagtaagac catcggtcaa
    42721 accaatttgc gaatactgta aagttattcg tcgtaatggt cgtgttatgg taatttgccc
    42781 agcaaatcca aaacacaaac aacgtcaagg ataagataga aaggagaaaa catggctcgt
    42841 attgctggag ttgatattcc aaatgacaaa cgcgtagtaa tctcattgac ttatgtttat
    42901 ggtatcggac ttgcaacatc taagaaaatt ttggctgctg ctggaatctc agaagatgtt
    42961 cgtgtacgtg atcttacatc agatcaagaa gatgctatcc gtcgtgaagt ggatgcaatc
    43021 aaagttgaag gtgaccttcg tcgtgaagta aacttgaaca tcaaacgttt gatggaaatc
    43081 ggttcatacc gtggtatccg tcaccgtcgt ggacttcctg tccgtggaca aaacactaaa
    43141 aacaacgctc gcactcgtaa aggtaaagct gttgcgattg ctggtaagaa aaaataatat
    43201 aggaggtaaa agtcttggct aaaccaacac gtaaacgtcg tgtgaaaaag aatatcgaat
    43261 ctggtattgc tcatattcac gctacattta ataacactat tgttatgatt actgatgtgc
    43321 atggtaatgc aattgcttgg tcatcagctg gtgctcttgg tttcaaaggt tctcgtaaat
    43381 ctacaccatt cgctgctcaa atggcttctg aagctgctgc taaatctgca caagaacacg
    43441 gtcttaaatc agttgaagtt actgtaaaag gtccaggttc tggtcgtgag tcagctattc
    43501 gtgcgcttgc tgccgctggt cttgaagtaa cagcaattcg tgatgtgact ccagtgccac
    43561 acaatggtgc tcgtcctcca aaacgtcgcc gtgtataatc atcgcattac actgcttttc
    43621 gtttaagagg gagtaactaa atgatcgagt ttgaaaaacc aaatataaca aaaattgatg
    43681 aaaataaaga ttatggcaag tttgtaatcg aaccacttga acgtggctac ggtacaactc
    43741 ttggtaactc tcttcgtcgt gtacttctag cttctctacc aggagcagct gtgacatcta
    43801 tcaacattga tggtgtgtta catgagtttg acacagttcc aggtgttcgt gaagacgtga
    43861 tgcaaatcat tctgaacatt aaaggaattg cagtgaaatc gtacgttgaa gacgaaaaaa
    43921 tcatcgaact ggatgttgaa ggtcctgctg aagtaacagc tggtgacatt ttgacagata
    43981 gcgatattga aattgtaaat ccagatcatt atctctttac aatcggtgaa ggttcttctc
    44041 taaaagcgac tatgactgtt aacagtggtc gtggatatgt acctgctgat gaaaataaaa
    44101 aggataatgc accagttgga acacttgctg tagattctat ttatacacca gttacaaaag
    44161 tcaactatca agtggaacct gctcgtgtag gtagcaatga tggtttcgac aaattaaccc
    44221 ttgaaatctt gacaaatgga acaattattc cagaagatgc tttagggctt tcagcacgta
    44281 ttttgacaga acatcttgat ttgtttacaa atcttactga gattgctaag tcaactgaag
    44341 tgatgaaaga agctgatact gaatctgacg accgtatttt agatcgtacg attgaggaac
    44401 tggacttgtc tgtgcgttca tacaactgtt taaaacgtgc cggtatcaat actgtgcatg
    44461 atttgacaga aaaatctgaa gcagagatga tgaaagtacg aaatcttgga cgcaagagtt
    44521 tggaagaagt gaaactcaaa ctcattgatt tgggtcttgg attaaaagat aaataaagga
    44581 ggaatacatg gcttaccgta aactaggacg cactagctca caacgtaaag caatgcttcg
    44641 cgatttgaca actgaccttt tgatcaacga atcaatcgtg acaactgaag ctcgtgctaa
    44701 agaaatccgt aaaactgttg aaaaaatgat tactctaggt aaacgtggtg atttgcatgc
    44761 acgtcgtcaa gcagctgctt tcgtacgtaa tgaaatcgca tctgaaaact atgatgaagc
    44821 aactgataag tacacttcta ctacagcact tcaaaaattg ttctcagaaa tcgcacctcg
    44881 ttatgctgaa cgtaacggtg gatacactcg tatccttaaa actgaaccac gtcgtggtga
    44941 tgcagcgcca atggcgatca tcgaattagt ataaaatcat caattttgtt gagtgttatg
    45001 atgatggagt cttgtgctct tagtctagct ctggtctacc gctaggattt cggtcctagc
    45061 gggaacactc atcataagtt gggatagtag acgcttgttt acgaaattgt ttttttctta
    45121 agaacaactt cgtaagcagg cgtttttgag tattttcgtt agaattatgc tatactattt
    45181 gaaaagaatc ctgtttaatg ttaaggtttc ttattttaag aagaattgga gtttacttat
    45241 gaaagccatt ataactgttg ttggtaaaga taaatctgga attgttgcag gtgtttctgg
    45301 taaaattgca gaattaggat tgaatattga cgatatctct caaactgtat tggatgaata
    45361 ttttacgatg atggctgttg tatctagtga tgaaaagcaa gattttacct atcttcgtaa
    45421 tgaatttgaa gcttttgggc aaactttgaa tgtaaaaatc aatattcaga gtgcagcgat
    45481 tttcgaagct atgtataata tctaggaggt catcatggat attagacaag ttactgaaac
    45541 catcgccatg attgaggagc aaaacttcga tattagaacc attaccatgg ggatttctct
    45601 tttggactgt atcgatccaa atatcaatcg tgctgcggag aaaatctatc aaaaaattac
    45661 gacaaaggcg gctaatttag tagctgttgg tgatgaaatt gcggctgagt tgggaattcc
    45721 tatcgttaat aagcgtgtat cggtgacacc tatttctctg attggggcag cgacagatgc
    45781 gacggactac gtggttctgg caaaagcgct tgataaggct gcgaaagaga ttggtgtgga
    45841 ctttattggt ggtttttctg ccttagtaca aaaaggttat caaaagggag atgagattct
    45901 catcaattcc attcctcgcg ctttggctga gacggataag gtctgctcgt cagtcaatat
    45961 cggctcaacc aagtctggta ttaatatgac ggctgtggca gatatgggac gaattatcaa
    46021 ggaaacagca aatctttcag atatgggagt ggccaagttg gttgtattcg ctaatgctgt
    46081 tgaggacaat ccatttatgg cgggtgcctt tcatggtgtt ggggaagcag atgttatcat
    46141 caatgtcgga gtttctggtc ctggtgtggt gaaacgtgct ttggaaaaag ttcgtggaca
    46201 gagctttgat gtagtagccg aaacagttaa gaaaactgcc tttaaaatca ctcgtatcgg
    46261 tcaattggtt ggtcaaatgg ccagtgagag actgggtgtg gagtttggta ttgtggactt
    46321 gagtttggca ccaacccctg cggttggaga ctctgtggca cgtgtccttg aggaaatggg
    46381 gctagaaaca gttggcacgc atggaacgac agctgccttg gccctcttga acgaccaagt
    46441 taaaaagggt ggagtgatgg cctgtaacca ggtcggtggt ctatctggtg cctttatccc
    46501 tgtttctgag gatgaaggaa tgattgctgc agtgcaaaat ggctctctta atttagaaaa
    46561 actagaagct atgacggcta tctgttctgt tggattggat atgattgcca tcccagaaga
    46621 tacgcctgct gaaactattg cggctatgat tgcggatgaa gcagcaatcg gtgttatcaa
    46681 catgaaaaca acagctgttc gtatcattcc caaaggaaga gaaggcgata tgattgagtt
    46741 tggtggtcta ttaggaactg cacctgttat gaaggttaat ggggcttcgt ctgtcgactt
    46801 catctctcgc ggtggacaaa tcccagcacc aattcatagt tttaaaaatt aagaaaatag
    46861 gagaaatttt aagttctatt taagattaga cgtgtatact ataatcatta aataaagacc
    46921 tcctaatatt atttgaaaca gataacactg aattagtttg aatttgattt tcatctaata
    46981 tctttattta atgaactcct aaactttttc ataataatct ccttcaaaag tcgcctgtat
    47041 gggtggcttt tattttatca ttcatgatat aatagaagca aacggaggac ggaaaatggt
    47101 aaaagtacga ttgtatttgg tacgtcatgg caagaccatg tttaacacga ttggtcgcgc
    47161 gcaaggttgg agcgatactc ccttaactgc tgaaggtgaa cgagggattc aagagttagg
    47221 aattggtttg cgagaatctg atctacagtt tgagcgcgct tattcgagtg attctggtcg
    47281 taccattcag accatgggaa ttatccttga agaacttggc ttgcagggga aaatccctta
    47341 tcgcatggac aagcgtatca gagaatggtg tttcggtagt tttgatggag cctatgatgg
    47401 cgatcttttc atgggcatta ttcctcgtat ctttaatgtg gaccacgttc accaattgtc
    47461 ttatgctgaa ctggctgagg gcttggtaga ggtcgataca gctggttggg ctgaaggctg
    47521 ggaaaaactc agtggccgaa tcaaggaagg ctttgaaatg attgcaaaag aaatggaaga
    47581 tcaaggtgga ggtaacgccc ttgttgtcag ccatggaatg actattggaa ccattgttta
    47641 tctgattaat ggcatgcatc cgcatggtct agataatggt agcgtgacga ttcttgaata
    47701 tgaggacggt cagtttaggg ttgaagttgt cggtgaccgt agttaccgag agctaggacg
    47761 tgagaagatg gaagaaggct ctatttaatc agtctagact tgcttgccat gagctaggga
    47821 tttgataaga atatcaagat aagaaaaaac agccgagggt actcctttcg gctgtttttg
    47881 atgtggaaaa ctaaagtgta atgctattgc ttttagagat tttcataaac aagagcaagg
    47941 aacctactgt tagaacagtc aggatagttg acaaggctgc ggctacaccg taatttcctc
    48001 tgagaacctc tgtataaata gctacagtca ttgttcttgt tttgacattg tagaggagga
    48061 tagaagtaga gagttttgaa atcattatga cctaagataa gatggctcca gaaatgatac
    48121 cagatagcat cattggagtt gtaatcttag caaaggtatt gagacgacta cttcctaagc
    48181 tttcagcagc ttcttcaata cttggtgcta tttgttgtaa gctagcaaca gatgagcgaa
    48241 tagtataagg taatcttctg acagatagag acataatcaa gatgaaagca gtccctgtaa
    48301 tcataagaaa tccacttcca aatagaccag tattgaagga agaaatgaag gcaatcccta
    48361 gaacggttcc tggtacaata taaggtacca tactgaggct gtcaattaag tttgtaaaca
    48421 aattccgttt tctaacggct aggtaggaga taaatgtcgc aaatagaaca actagaacta
    48481 aggcaatcaa agggatacga atggtattga aaatagcaga tcccatacga ttgaaagcta
    48541 ccttgtaact gtttggagaa taacctttaa cagataccat acctgatgtt tttaggaaag
    48601 aggtataaat taagtagatt tgaggtaaaa cagagataaa gataattccg tagactgttg
    48661 cataaatggc agctattttt ccttttgtag tttttttagg ctcaattgga tggagcagat
    48721 tcatgctgaa actgtagcgg tttgcaatgt gtttttggat aaggaaaatt gccaagacaa
    48781 tgataatcgc cataattgca aaagcagaat ttcctccaac ctcgctaata aattgggtat
    48841 aaatcaggac agggaaggtc cgatatcctt cgccaatcaa cataggcgtt ccaaagtctg
    48901 agaatgctct cataaataca agcaaggagc tgctagtaag gttggaacta ggagaggtaa
    48961 aacaaccgtt acgataggtt taaatccgaa ggaccccatg ctttcagctg cttcaagtag
    49021 agaattgtca atactgttca ttgttccagc aacatataga aataccagtg ggaatagttg
    49081 cagtgtaaag acaagtacaa ttcctttgaa tccataaata tcgatagctg gaagatgaag
    49141 ggcatttgtc aaaaatttag tgatgacccc atttcgtcct agcaagagaa cccaggagta
    49201 ggctcctacg aaaggagctg acatggaagc aatgataatc aatatttgta gaaatttctt
    49261 ccccttgaag tcatacatag agaagagata agctaatagg gttcctacaa ctaaggaagt
    49321 gacagtagcg gtaatggaaa ccttgaaact gttgactagt gtctcagagt agtagacttt
    49381 actaaagaaa gtgacaaaat tagctagtga gaattgtcct tcatgtataa gtgcttgctt
    49441 gagcacggta acgataggat aaacgagaaa gacaagatag gtaagaaaga tgaagaaaga
    49501 ggaggttgtc caaatattta gttttttaca ttccatggtt gactcctttt atcaggtttt
    49561 gggaaccatc tgcagaaaag atgtttaatt tttgcgtatt gattcgtaga cgaatacgat
    49621 tgcctttttg tagttcttct tcaaaagttg attcttcact aacttgaatt tttgaggcaa
    49681 aacctgtctc aatgaaatac tccgtattta gtccaagata gacgctatcg ctaatagttc
    49741 cttcaatatc tccagattca tctttgataa actcttcggg acgaatgctt acatgaatag
    49801 cttgctcctc aacctgatca agagctggca ttcgaagggc atagccatct gaaaagacga
    49861 tataagcgcc gtcgctccgt ttttcaagat tagtagggat aatatttgtg cgtccgataa
    49921 aggttgccac aaactcatta gctggtttat gatagagttc ttttggtcgg ccgatttgtt
    49981 ggatcacccc atctttcata acagcaattt ggtctgaaat agccatggct tcttcttggt
    50041 cgtgggttac ataaacagtt gtaattccca cttcgtgttg gatttctcgg atggcttgac
    50101 gcatatccaa gcgaagtttg gcctccagat tactaagtgg ctcgtccatg aggagaacac
    50161 ttggattaac cgctaaggcg catgccaagg tgacacgttg ttgttgtcca ccactgagtt
    50221 tatcgggctt tcaatccgca tattgagcaa tttgcatgag ttcaagatac ttgttggtct
    50281 gttgaatcaa ttcttctttt ggaaccttct tttgcataag accaaaagca acgttgtctc
    50341 ggacagtcaa atgtgggaaa atagcgtagt tttggaaaac cagcccgata ttgcgtttgc
    50401 tgggttccat attattgatt tttgtatcat cgaagtaaaa ttctccatct ttgatactgt
    50461 tgaaacctgc aatcatacga agaagggtcg ttttcccaca tcctgaagct ccaagaaggg
    50521 taaagagact tccttttgga attgtaatgt tcaaattctc aataacaggg acatcgtggt
    50581 agattttttt ggcgttaata atttcgatct cactcatagt gaacctcttt tactgtttag
    50641 attggatatc tgtaaagact tcgttgtatt tcttaacgat atctgattta ttcttgatga
    50701 cataatcata atcttcagtg agtgttttga ttttgtcaat tggtttcatg ttttcgcttg
    50761 ttttagcatt tttacgaaca ggacggttag tagtggttgt accaagtgta tcttgtactt
    50821 cttgagagat aataaaatcg ataaatttct tggcattttc catattttta gcttttttaa
    50881 cgatagcagc actagcaggt aggaagacgg ttccttcttt tggatagact actttaatgt
    50941 tagctccgtc atttaagagt ttaactgctg gatcctcata agagagacca acagccattt
    51001 ctccatcaac gactgcttta tagacaccag atgaacttga accgatttta tagtgtattg
    51061 aaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcctg
    51121 attaatttgt cctgttctta tttcatttta ctataccatc aataagtgtg aaaagatctt
    51181 ttacataaga ccaagcctta tcatctttgt aaccaccttg agcttgtagc atatttgtta
    51241 attgagcaaa ggcgctagaa gagtttgctg ggtcagcagt tgcgattttt ccttttagtt
    51301 caggtttgag aaggtcgcta tatccttcga tgttcatgcc tttagttaaa tcagggtgga
    51361 cgattaaaac actaccatct agtgtataag gagtagagaa gccagttgtg ttttgatatt
    51421 ctttgataac attatcattt tcttttgaaa tatagttttc aaagagttct ccgtgggtag
    51481 catattgtgt ataagaacca ccaaagataa catcagctac aggaacttct ttttctgact
    51541 ctagtttttt gaaaagttct ccagtaccag cttgaatcag ttctattttg ataccatatt
    51601 tttcttcaaa ggcaggaata gttgctccaa ttaagccttc tgagtttggt gaataaacga
    51661 ctagcgaacc accgtctcct ttatcagatg aactgtcatc ggcagattca ttagaagaac
    51721 aagcagcata atacatccat ttctttttca tgatggatat ctccgttgtg ttatttaagt
    51781 ttattttaaa acaatgtaag cgtttttaaa acctacaatt ctattctata gtgtattgaa
    51841 tctataacag tacac
//
LOCUS       DAVLHM010000007        51589 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLHM010000007 DAVLHM010000000
VERSION     DAVLHM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.007"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VXE45_000454"
     CDS             complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VXE45_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0788549.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
     gene            1722..1904
                     /locus_tag="VXE45_000455"
     CDS             1722..1904
                     /locus_tag="VXE45_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0788550.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            1849..2698
                     /locus_tag="VXE45_000456"
                     /pseudo
     CDS             1849..2698
                     /locus_tag="VXE45_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(2750..3112)
                     /locus_tag="VXE45_000457"
     CDS             complement(2750..3112)
                     /locus_tag="VXE45_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788551.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(3403..5283)
                     /locus_tag="VXE45_000458"
     CDS             complement(3403..5283)
                     /locus_tag="VXE45_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0788552.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(5277..6146)
                     /locus_tag="VXE45_000459"
     CDS             complement(5277..6146)
                     /locus_tag="VXE45_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0788553.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(6230..8875)
                     /locus_tag="VXE45_000460"
     CDS             complement(6230..8875)
                     /locus_tag="VXE45_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0788554.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(8966..10246)
                     /locus_tag="VXE45_000461"
     CDS             complement(8966..10246)
                     /locus_tag="VXE45_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0788555.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            10417..12501
                     /locus_tag="VXE45_000462"
     CDS             10417..12501
                     /locus_tag="VXE45_000462"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0788556.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(12541..14220)
                     /locus_tag="VXE45_000463"
     CDS             complement(12541..14220)
                     /locus_tag="VXE45_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0788557.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGSNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            14975..16204
                     /gene="arcA"
                     /locus_tag="VXE45_000464"
     CDS             14975..16204
                     /gene="arcA"
                     /locus_tag="VXE45_000464"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0788558.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            16262..17278
                     /gene="argF"
                     /locus_tag="VXE45_000465"
     CDS             16262..17278
                     /gene="argF"
                     /locus_tag="VXE45_000465"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0788559.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            17443..18390
                     /gene="arcC"
                     /locus_tag="VXE45_000466"
     CDS             17443..18390
                     /gene="arcC"
                     /locus_tag="VXE45_000466"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0788560.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            18601..20112
                     /locus_tag="VXE45_000467"
     CDS             18601..20112
                     /locus_tag="VXE45_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0788561.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            20134..21465
                     /locus_tag="VXE45_000468"
     CDS             20134..21465
                     /locus_tag="VXE45_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0788562.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEENLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            21560..21687
                     /locus_tag="VXE45_000469"
                     /pseudo
     CDS             21560..21687
                     /locus_tag="VXE45_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(21852..22142)
                     /locus_tag="VXE45_000470"
     CDS             complement(21852..22142)
                     /locus_tag="VXE45_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788563.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(22130..22381)
                     /locus_tag="VXE45_000471"
     CDS             complement(22130..22381)
                     /locus_tag="VXE45_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0788564.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFDGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            22585..22662
                     /locus_tag="VXE45_000472"
                     /pseudo
     CDS             22585..22662
                     /locus_tag="VXE45_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(22780..23664)
                     /locus_tag="VXE45_000473"
     CDS             complement(22780..23664)
                     /locus_tag="VXE45_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0788565.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(23809..24960)
                     /locus_tag="VXE45_000474"
     CDS             complement(23809..24960)
                     /locus_tag="VXE45_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0788566.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(25106..26872)
                     /locus_tag="VXE45_000475"
     CDS             complement(25106..26872)
                     /locus_tag="VXE45_000475"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0788567.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(26929..30045)
                     /locus_tag="VXE45_000476"
     CDS             complement(26929..30045)
                     /locus_tag="VXE45_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0788568.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(30055..32349)
                     /locus_tag="VXE45_000477"
     CDS             complement(30055..32349)
                     /locus_tag="VXE45_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0788569.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRV
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(32408..33208)
                     /locus_tag="VXE45_000478"
     CDS             complement(32408..33208)
                     /locus_tag="VXE45_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0788570.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(33205..33978)
                     /locus_tag="VXE45_000479"
     CDS             complement(33205..33978)
                     /locus_tag="VXE45_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0788571.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(34003..34473)
                     /locus_tag="VXE45_000480"
     CDS             complement(34003..34473)
                     /locus_tag="VXE45_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0788572.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(34464..34895)
                     /locus_tag="VXE45_000481"
     CDS             complement(34464..34895)
                     /locus_tag="VXE45_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0788573.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(34888..35328)
                     /locus_tag="VXE45_000482"
     CDS             complement(34888..35328)
                     /locus_tag="VXE45_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0788574.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(35340..35978)
                     /locus_tag="VXE45_000483"
     CDS             complement(35340..35978)
                     /locus_tag="VXE45_000483"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0788575.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(36093..37496)
                     /locus_tag="VXE45_000484"
     CDS             complement(36093..37496)
                     /locus_tag="VXE45_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0788576.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELNSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            37672..38445
                     /locus_tag="VXE45_000485"
     CDS             37672..38445
                     /locus_tag="VXE45_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0788577.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(39616..41121)
                     /gene="adcA"
                     /locus_tag="VXE45_000486"
     CDS             complement(39616..41121)
                     /gene="adcA"
                     /locus_tag="VXE45_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0788578.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(41131..41937)
                     /locus_tag="VXE45_000487"
     CDS             complement(41131..41937)
                     /locus_tag="VXE45_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0788579.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(41930..42634)
                     /locus_tag="VXE45_000488"
     CDS             complement(41930..42634)
                     /locus_tag="VXE45_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0788580.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(42634..43074)
                     /gene="adcR"
                     /locus_tag="VXE45_000489"
     CDS             complement(42634..43074)
                     /gene="adcR"
                     /locus_tag="VXE45_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0788581.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(43229..44497)
                     /gene="dltD"
                     /locus_tag="VXE45_000490"
     CDS             complement(43229..44497)
                     /gene="dltD"
                     /locus_tag="VXE45_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0788582.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(44490..44729)
                     /gene="dltC"
                     /locus_tag="VXE45_000491"
     CDS             complement(44490..44729)
                     /gene="dltC"
                     /locus_tag="VXE45_000491"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0788583.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(44743..45987)
                     /gene="dltB"
                     /locus_tag="VXE45_000492"
     CDS             complement(44743..45987)
                     /gene="dltB"
                     /locus_tag="VXE45_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0788584.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(45984..47534)
                     /gene="dltA"
                     /locus_tag="VXE45_000493"
     CDS             complement(45984..47534)
                     /gene="dltA"
                     /locus_tag="VXE45_000493"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0788585.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(47555..47686)
                     /locus_tag="VXE45_000494"
     CDS             complement(47555..47686)
                     /locus_tag="VXE45_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0788586.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(48000..49178)
                     /locus_tag="VXE45_000495"
     CDS             complement(48000..49178)
                     /locus_tag="VXE45_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0788587.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(49630..50906)
                     /gene="ltrA"
                     /locus_tag="VXE45_000496"
                     /pseudo
     CDS             complement(49630..50906)
                     /gene="ltrA"
                     /locus_tag="VXE45_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        15405 a        11142 c         9246 g        15796 t
ORIGIN      
        1 ctactccccg attagaattc tttttaggtt tagctacatc agtttcttgt tttatattat
       61 ctactttttc aacaatgata tcattactag tagataaatt tgatttaaga acatctttta
      121 tatgttctga tgttacatag aacttaacag tttcaggaat tgcaaatgta tcttttttca
      181 cagaaaactc tgtactttta ttcttaatat gaatttcctt taatgaatct aagacgccac
      241 ttaggaagaa ggacggcaat gagttgatat tattaccaat tgttaaactt tttaattttg
      301 gtaaaccgtt cataacgtgt ttaccaaaat ttttaacatt atctggtaat ataagttctt
      361 ttaattctaa attaccgtaa aaggctaaac gttcaatagt ttctaaacta tttggtaagc
      421 taatttcttc aagtttaatc gcatccgcaa atgcaaaagt accgattttt tctaaacctt
      481 cattcaattc gagttttttc aagtaagaat ttttattaaa cgaatatgat gcaagttctt
      541 ttgtctcttt aggcgtttta taactttcgt catttttttg acttggataa taaattaatt
      601 gagttttatc ttttgaaaac aaaacaccat caactgaggc aaacgattca tttccttctt
      661 caacatcaac atgttttaag ctagtagtga gtctaaatag attacttcct aatgttttaa
      721 ccgattttgg taatgttagt ttctctaaat ttgataaatt agcaaaagcc tcatgtgata
      781 ttaattctaa ttttgaactt gaggaaaagg ttagcttttt caatttttga ctaaaagaaa
      841 atgcacttgt tccaatatat tctagagatg caggcaattc aatctcttct aattcagaaa
      901 aatcaaaagc tctatcttca attttctcca gctgactgcc tttgtcaaaa ataatagttt
      961 tagctttact tccatggaag cctttttttt gtattttttt tatgcttgat gggatagtaa
     1021 tagagctagg atagtagaca attctacctg tttcatctgg ataataacta aaagcttgac
     1081 tagctacttc agtaacggta aatactttat cacctactgt gatttttgta ggaatcgtga
     1141 atggttttcc atcttgacca gcttcaaact ctacaggagt aactccatta cccacttgaa
     1201 cagttcctat gttaccttct acagttagaa ccttatattt gatattattt tgttgaataa
     1261 tacttccaac tttagtctct ttgattactt ccgaactagg agtatctgct aggattggtt
     1321 cattagggac atatgctgct aaaataaccg cagctgtagt taatgataat attgtagttt
     1381 ttttcattta aatttcctta catatttatt ttctaataga tataaaatta taactttgct
     1441 agccgttgtt ataaaaagtt ttattcaatc attatctagt agaatagagt agtacatttt
     1501 ataaattgtc atctctccat aaacacagta tatcattttt aaattttaag tcaaggaaaa
     1561 ttaacccact ttaatttctt ttttaacccg tgttaaaaaa gaaattaaag tgggttaaaa
     1621 aagaaattaa ctgagtaaaa actctcgaaa ttcaattcgc tatattatca ctcaacttga
     1681 acaaatacca gaaccacaaa aaacagatgt aaaggaaaaa tatggactta aaatttgaag
     1741 gggttgattt agaatacaaa aaagctaaaa acaatcttcc agagtctttc tgggaaacct
     1801 actcagcatt tgcaaataca aatggcggga aaataattct cgggatagat gaaaaaaaca
     1861 ttgacaccta ccaaagagtc aatagactcc ctgcgaaatt atgaagcaag taaacaatta
     1921 actgatacac gatttaagcg tcttgttggt gttcagcgca cgacttttaa agagatgtta
     1981 gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa acctaaatta
     2041 agcctagaag accttcttat ggccactctt caatatgtgt gagaataccg cacttatgaa
     2101 gaaattgcgg ctgattttgg tatccacgaa agcaacttaa tccgtcggag ccaatgggtt
     2161 gaagtaactc ttgttcaaag tggtgttacg atttcaagaa ctcctctcag ctctgaggac
     2221 acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc ctaaaaaaac aattagcgaa
     2281 tcattctggt aaaaagaaat ttcacgctat gaaggctcaa gcgattgtca caagtcaagg
     2341 gagaattgtt tctttggata tcactgtgaa ctattgtcat gatatgaagt tgttcaaaat
     2401 gagttgcaga aatatcagac aagttggtaa aatcttggct gacagtggtt atcaagggct
     2461 catgaagata tgtcctcaag cacaaacttc acgtaaatcc agcaaactca agccactaac
     2521 agctgaagat aaagcctata accatgcgct atccaaggag agaagcaagg ttgagaacat
     2581 ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
     2641 cttcggatta cgaatgaatt tgattgctgg tattatcaat catgaactag gattctagtt
     2701 ttgcaggaag tctattgaaa tactaagcct acacagactg atttcaattt taccattctt
     2761 catagtcaaa accatcataa tctggatatt gttctggcga cgttccaacc gaacgtacga
     2821 gataagcttc ttcgtcctct gtctcgattt ctctcagcac ttggcattca aaacgccatt
     2881 catcaccgaa gtcgaaaata aacttaaatt tttgtttgac acttaggcta tccagataga
     2941 cattttctgt gtaacgttct tcaacatcgt cactaacaaa gctaagaaag taagaatctg
     3001 catgactcca ctcaatatta tccatgaaaa atgcgtgagc atgatcattt gcaaaatcaa
     3061 aactccataa aatcacatct gctagttccg ctaacgtttt tgtttttgga atctatatat
     3121 gtcggtagca acctttttta aatttgacgg aaatgatcca agcctctaca gatgctggct
     3181 tttcagcttc tatttcttgt tttactaatt ttaactgtag catttgaaac cagataattc
     3241 ttctgtttca cgcgaaacac cctgcgccaa gcaaggtgtt cttgttttta tactcaatga
     3301 aaatcaaaga gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg
     3361 tagatggaag ctgacgtggt ttgaagagat tttcgaagag tattaagtcg tataaatcgt
     3421 cgaagctgtc gcaatggtat gccactggtt agctgtagtt gctgcgaaat ccttgtctgc
     3481 gtagaagtca gtaaatggta ggatttcaac ttccagctcg tcgatgcggt caagctggcc
     3541 agccagataa acctcgatac ggctttctgc tcgtttgatg cgttgcaaga gtccgcccat
     3601 acggatgtca actgtatcca aaccaaagac cttgttttct ttcagccatt ggtgactaaa
     3661 gagggcatgg aagtcttcaa tttggcttct aagttctggt aattcttgtc tggcgatttg
     3721 ttgtaaactt tctttatcat ccgcttggta ggcctgacga atgcgtcgtc ccacatctac
     3781 tttgctactt aaaatagcat tcaactgggc ctgagtttca aagagataag catagtttcc
     3841 agctttttct ttaatgttag caagcgtctc agcagcctga gcgaagtgcg gtttgtcctg
     3901 ttcaggtgtc atgtgtcggt caagtatcgg acagagaaca tcctgataaa agacatatcg
     3961 gttgggattg atgccactga gattgcctgg taggtctggt aagaggttgg caaggtcaat
     4021 ctgcataaaa tcctcaaccg ttagaccagt attggtcttg aagtgcgcag acaaactatc
     4081 taggtcatgg cgatagctga gttctgccca gatttgcaag cttggtagga tagagaactg
     4141 ggcagtttca cccccattgt ctccccaacc cgttacgatg acttctttaa tctgattggc
     4201 acggcaggct ttattagcct cgatagccac tagacggcta aaatggttgt gaggtgtaaa
     4261 gccaatccac ttccaagctc cccctgcaaa tgcaaggtca tggctaatct tgtgatgatt
     4321 gcggaaatta cggttgtatt tttcctcgct atcctgataa taatcccagt aaaccagagt
     4381 cacacggtct ttgagacggt ctaggtagac acgagtttcc tctggaattt ccacatcacg
     4441 gtcgtactgg ccatccgctg acatgagttt gaagaacata tcactccaca tctggcagtg
     4501 gaaaccatat ttgtcagcaa tatccagcac gcgctccaag tgttggcaca tgaggagact
     4561 acgatccaca acaccgttca aaatcaggta gcgtcccaaa ccaaccaagt gggcttcgtc
     4621 catcccgata ttgaccttgc gagtcttcag tttagacaac gtggcaaaca tgccatcaat
     4681 caggtcataa accttttctt cgccaatgag aagaatgtcc tctacatcac ggagctcctg
     4741 cacttccttg acaccccatt tgacaaaggc cgacaagtgg gccaaggtct ggatgcatgg
     4801 tacaaaggtc atgtcaaact gttgggcata ggcttcgatt tcctgcaact cctctgctga
     4861 ataagctcca cggaaatagc caaagtaagg ctgtccttca atctggtaag tgtcttccat
     4921 gtaaagctca aaggttgagt agcccatgag agccaagacc tcaatcatct gcttggcaga
     4981 agccacattc agcaccgcat ttcgagaaca gtcaaccatg taagccaaat cttcgtaagc
     5041 tgcttgttcc tcaatctcta ctttatcagc ttctgctaga actgttacca acaaggacaa
     5101 ggcacgataa agttggtgag gtttgcgata ggtcaattga tagtgacctt cctcaccctg
     5161 gatagagata gatgcttggt cagactgagt gacagccact tccacatctg gtagagaaat
     5221 gtgacctttt aaaacctcaa tagcttgcgt ttgtttggga ctaagtccta taaatcttac
     5281 cactgctttt cctcctgtag ccagttgaca agagcaccgt agagattggc atctgcgtga
     5341 taggtgcagg cctggataac tggtgcgacc gtgtattctt cgtaggcatc gacaaagtct
     5401 tcaacagcct tcttaacacc ttggataaaa tctggatttt gactgataga gccacccaga
     5461 ctgatgacat ctggatcgat gagatactgg atattgagca agccttgcgt caaattgcgg
     5521 ttcatgcgct caatggcttc ttgacaaaga gcattaccag ctgcggcctc ttggtaaatc
     5581 ttgcgaccgt cccaatcagt atgaccagat ttttcaatca cgtatcgtac catattccca
     5641 gttgatgcta gttgcgacca gttattaagt ttttcagcag gggcaagggt tgtcatgtag
     5701 ccaaattctc cacccagacc gtggcgacct cgatgaagtc taccattgat aatcatggct
     5761 ccgccaatcc ctgtcccaat cacgacacag gctgcatttt caagctctgg atgagctagt
     5821 agttcactga gtccaacgca gttggcatca ttttctaaat ggacaggtag ctgataagag
     5881 ctaagcgcct cataccaaga aaagccatgg atgtagggca ccgcactgaa gccatcaatc
     5941 acacctgtct cttgattgac tgcacctgga acactcatag caatcccact gtaatcctgt
     6001 tctgacaagc gttgatctag ccacgctagt aaatcctcca agttttcagg cgttgaaata
     6061 cttgtcttat ccagtatttt cccatcagga gtcagactgg caaacttaat cccagtccct
     6121 ccgatatcaa tcgttgcaat ggtcattgtt tttaccataa aaaggggcga atcagcagtt
     6181 agttcttact ttttcgcccc tcctttcttt tgatgtttac tttttgaaat taaatttctt
     6241 cttttttgat gaattctgta cgaatctctt gtggagccaa tagtcctgaa tgaactggat
     6301 atggtcgctc aagtaagtca agaatggttt gttgatgttc tgatatgcgc acattttctt
     6361 gactcatatt atagtaacgg aggacatagc cttcttcatt ttccgccact ttaaaggctg
     6421 ttggacaaac ttgcggtatg ctgagaacag aatggctcaa gaggctacca gtcgcaacca
     6481 cgcttccttc ctgtctagca agctgaaggc tggtaaacgg tgtctgcaag gctttggcac
     6541 gacgataggc tgagaagcgt tcttgggctt ggtggcattc aatcgcaaat tcgacttcaa
     6601 actcacgcaa gcattgtgct tctggcgttg ggaagtagcc ccagtcacct agctcacctg
     6661 atgcacgcaa aatggtcacg gcaatggtgt tatccccaag gatttcgtat tcattcaatc
     6721 ccttgttgga tacagtcacc cctttttcat cgtcatacag actgacaaaa gcttgttggt
     6781 gttgaggatt ttcaggattt tcccatgaag cagctggttt gtttggtcgt gtcaccacct
     6841 catagatact ttcagaatca ttgcttggac gcgtgttatg agtcttgacc aagagacgga
     6901 tacggtgatc cttggcagtg ttagtaaagc gagtcttgaa gcggatttgt ggattgtcaa
     6961 caaagacaat caactcagtt tccagaggaa tgtttgtcaa ttcttctgac cgtccagcct
     7021 cacgcttcat aaactcgatg ataccttgtt gctcttcttc tagcttttca tccgcactga
     7081 caggcacggt caattcatgt ttgagcaaga ttttagcata gcgatctgtg ttttccaaga
     7141 cctcgtggcc cttaagctct gcaaagattg gctctgttcc ttttggttgg aaatagatat
     7201 actcgtttcc gatgtcaccc cggtcttcaa agcggataaa gtcttcatag gcttcgtgag
     7261 ttgtcttgtc atagactgtg atgttgtcat ccacactcac cgttacgaat ggtgtatcaa
     7321 tcactccgtt ttggtaaata ccctcacggt gttcttgttt tccttccagc aattggaagg
     7381 ttgtccaaga aagcggcgct aggtgaactg gaatggtcac gcgcacttgt cgagcaatac
     7441 gagcttggcg gaacttatct tttggtaaat cgtactcaaa attagctccg aggtcttcga
     7501 ttgtagcctc tacaggacga ccatccaagt cctccacacg gtaacttggc aagataagag
     7561 cagccatctt tttgtagcct tctgttgggt gcaattcctt gaaatcacaa gtcgccacat
     7621 caatcactgt gctgacagta tcgaccttat catgcaagcc tgtgttaatg acagtaaaga
     7681 gatagtcact ttgagcctta tccgtagcaa ttttaccctt ccactcgttg agcaagttac
     7741 ttttaacaaa gtttcctact tggttgacct tggcaaaacg cgtttccatc tcgcggtgaa
     7801 cttcgtccac gctacagcca cagatactat catgtggcgc gttctgcaaa agtgttttcc
     7861 aagcataggt caactggtcc ttgtggttgt gtccaccagt gataatagtc aagggttcta
     7921 ccacttgctc taggaggttg ctattttctt ggaaggcttg tttcaggtaa atgcgggatg
     7981 aagaagtgtt ggcaagtgtg taccagccat ctgtttcctg actggtcaac tcgcctgtaa
     8041 cagttgataa gtgttcagga agcgcacctt ctacagcttg aacatattca tcaaaagaac
     8101 tatgaacaaa gattacatcc gggaagagtt catttgccac acgaatggct tcgctcagat
     8161 ttttctgtac aggctggtgg tcacagccgt tcatcatcaa ccattggttg gtcgaagcgt
     8221 aggcacgcac atctgacaat ttttgtttcc agaaggtcaa ggcctcatct ttgtcaactg
     8281 ggatttcatt cccattactg taccagttgg caaagagaat acctaaaaca cgactaccat
     8341 ccacaccctg ccagtacatt tctgaaaact gggatgtaaa ctgctcatct tcaaggactt
     8401 ggttgtcaaa tccaatcggc ttcacaccac gaccaaaggc cgccacatga atgcctgatt
     8461 tttgaagaat ttgaggtgct tgtcccatat ttccaaaggt atctggaaag tagccaatct
     8521 gggttgattt accccatttg gcagcttctt gttgaccaat caaggtattg cggacattgg
     8581 cttcacttga aatcaaataa tcatcctgca agatgtaaaa gggaccaatt ttaagcttgc
     8641 cctcgtcaat gtagcgttgg accttgtcgc gattttcagg gcgaatttgt aagtagtcgt
     8701 caaggacaat agtttgtcca tccaagtgga aactcttgaa ctcagggtca ttttcaaaga
     8761 gatcaaagag attgtcaaac aattccacca actgcatacg atgactttca aaaggcaagt
     8821 accactcacg gtcccagtga ctatgtgaga taatatgtac aacaacattt tccatgaagt
     8881 aaaacctcat tctaaattta aattttaacg ttttaaatgt aaacttgtga ttctgataag
     8941 aatcggttga gctaaagcga gccccttagc gaatatccaa gtaatccaag accaactcac
     9001 agaacatcat gttagcccag gagaaccatt cacgagagta gagagttggg tcatccacgt
     9061 ggaagctttc atgcataaga cctgtaccgc catcgcaggc aaccagctga tccagcaaga
     9121 agtttttctc tgccttatct cttgttgtca agccttggat agaaagggcg attggccaga
     9181 tatagcgata gaaggtatga gaacttccaa gaccgctagc gtattctcct tggtagaaat
     9241 atggattttc agagctcaga atggtacggc gagtagcttg atacacttca tcatcgaccg
     9301 aacagtagcc cagatagggc gcagctagta gacttggtac gtttggatca tccataatgc
     9361 tggcatttcc taggccatcc acttcaaagg cataaatctt ttcaccctta ctgttggtgg
     9421 tgtaagcgta gttttcgatt ccttcttgga tttcatcctg aagacgcttg gcatcagcaa
     9481 taacactctg gctatcagct aggtttaatg ctgcgaagat ttcttgcaca taacccaaga
     9541 ctactacagc aaacatattt gacggaatca agtaactata ctggcaacag tcatcactcg
     9601 gacgaaaggc tgaccaagtc atacctgtca ctgcaaagtc aggtccaaag ccatcattta
     9661 ccaaggtgtc ttccttacgg tccgtatctc ggacaaaacg ataaggagag ttcttgtggt
     9721 cttgttcaac tgtccataga tggagaattt ccttagtcgc tgcgacaaaa gtctcatcaa
     9781 actgactagt ctcgccagtt tctttccaga ggagataagc caactgcaaa ggatagcaaa
     9841 gcgagtccac ctcatacttg cgttcccaaa tccagccatt aaggtcggtg tggtcggtct
     9901 cgtggtgccc cttccagttt tcctctatgt tgaaggaatt ggcataagga tccttgagta
     9961 ccaaggtcat ctgacgtttg accaaacctg caatggtctg acgcaggagg gcatctcttt
    10021 tagctacatg caggtagggt ctgagctggg ctgtcgaatc ccgaagccac atagcaggaa
    10081 tatccccagt caagacaaaa gttgaaccat cttctaagat ttcaaccgta ttgtccaagg
    10141 tatcggtgta gcaacgctcg aaaacatcca cccactctgg atggtcctta gcccgctctg
    10201 ctacttcatc tagccattct ctaacaattt ctttcgaata aatcatcgtg caattccctc
    10261 tttcaaacaa gtttcatgtt cagtatatag cttttgagac agaaaataca tacacaaatg
    10321 atagtcattt ttctacaaaa tagttatttt tgaaactcct tttctaaagt ccctcttttt
    10381 ctgatataat gtagaaaaac agctaaagga aagactatga aaccactact tgaaaccatc
    10441 gatacccgct ttggtactgc tagcaagcat gccttctctt ggggaaatac cctgccatac
    10501 acaggcgtgc cttttgggat gaattacttt gtgccccaga ccagtgacca ggatggatct
    10561 tggttttttg atccgcatct gcctatcttt caggggattc gattaactca ccagcccagt
    10621 ccttggattg gggactactc ttggctcctt ctgacacctg tcaccagtca actgggggga
    10681 gacagcctct ttcaccgcca gtcttcttat gatatagata aagcttgctt ccagcctcac
    10741 tatttgaagc tcttttctct gcgttatcag attgaaaccc agctcacacc gacttgctac
    10801 ggtgcttcta ttcgtttgaa gcaaaagcaa ggcaaagccc tctccctcta tcttcacgca
    10861 acagatgaac tgacagtaga gcaagtagat aagcgaactc ttgccctgcg acaagaaggt
    10921 aaaactgaaa ccaacaaaaa ttcgctaacg atgttcactg ccctgcaaat gaacacggat
    10981 attcttgcta tcagccaaga agctggggac tggcgaattg acttagcaag tagtcaaacc
    11041 gagatgcaac tagccacttc tttcatctct ccttctcaag cactgcttaa tctacctcaa
    11101 gaagattttg atagctgtaa agcaagtgcc caagcggatt gggaaaatct cctccatcgt
    11161 tttgacatta tagagacagg agaggctgac cgaaccttct ttgaccactg cctctacaga
    11221 ctcttcctct tcccacagac tttttatgag gttgatgagt cagggcaagc catccacatg
    11281 gatctggcta ctggtactgt caagcctggt gtcctcttta gcaacaatgg tttctgggat
    11341 accttccgca ccaccttccc cctctttgcc cttatcatac cggagcacta tcaacgcttt
    11401 ttagaaggtt tcctcaatag ctaccgcgat actggtttcc ttccaaaatg gctggctcca
    11461 gatgaacggg gtatgatgcc aggtacactt ttagacggta ttatcgcaga tagcgcctgc
    11521 aaggacatgg cccctgacct agaaggagaa ctcttccaag ccatgctcga aacagccagc
    11581 aaagccgacc ctctcggaat caatggccgc cacggactag cccaatacca agaactaggt
    11641 tacctctcta ccgaccacca cgaaagtgtt agccatactc tagactatgc ctatagtgac
    11701 ttttgtatcg ccagctgtgc caaaaaacta gagaacatag aaatcgctga aacctacaag
    11761 gctgcttcac aaaattaccg ccagctattt gacgctgaga caggttacat gcgagcacga
    11821 gacaatcaag gaaactttca ccctgacttc tctccttata gttgggggcg agactacgct
    11881 gaatgctctg ccattcaagc tactttaggc gttctccacg acatccctgg cttaatccaa
    11941 ctgatgggtg gaaaagaaac ctttagcaac tatcttttga aagcctgtca agatgctccc
    12001 ctctttgaaa caacaggcta tggttacgaa attcacgaaa tgagcgagat ggctactgct
    12061 ccttttggac aaatagccat ttccaaccag cctagtttcc acattcctta tctcttccgc
    12121 tacagcgatt accctgacta cactgccctt cttatcaaga cgctccgtca gaaagctttt
    12181 cacccaagtt gggaagccta tcctggagat gaagacaatg gtagtctctc tgcttggtac
    12241 atctggtcag ctctcggatt ttatccaacc tgtccaggaa aaccaagcta tgacctcgga
    12301 atccctctct ttgaccatct acgagtctac ctcgctaaag aagataaatg gctggatatc
    12361 catactaaac aaaaccacaa ccattttaac tttgtcaaag aatgccgact ggacaaaaca
    12421 ctcgtatcaa ctattcaaca ccaagacctc ttaaaagctg aacaactaac tttcaccctc
    12481 agctggttac caagtcacta ataaccaaaa gaacctttgc atcgcgcaaa ggttcttctt
    12541 ttatgaaact tggacttgaa gttgatccac aagctgacca tccaccgtta ggttcagata
    12601 gaaatccaag gttttatctc ctgcgaaata cagggttggt agatgcaaat cttttttgct
    12661 ttcccctgct tggaattgaa ggacttgaat ctcatcctga taggcgacac catggacacc
    12721 tgtccccggt tgaatcgaaa tcttagcctc taaagaggag ctactttcac tacgttcaat
    12781 cctaaaatga agagtctctc cctttgccac agctaggctt ttttctgcaa atgctagccc
    12841 ctgaacagct actgtttgtg ataacctcgg agttttatag agtgaaatct tggtcaacaa
    12901 aggcaaagcc tgtgattctg taatgactac acgtatcttc tgtgcttcaa caactgctcc
    12961 tcgtaagaga cgtttgtaac caacagtatg acccgaacca aactcctgcc agacaccatc
    13021 cacctctact tgcacatgaa aagcagcgat tcgttgccct agcttcaaat cttctcttaa
    13081 ctcaattaca tcaaaagttt taggagaacc taagtcgagt tctaactgga tgggcaagtc
    13141 tgcatcgctt gcccaagagc tggtctcaag gccgtctgtc aaatggcgac aagcaaagtc
    13201 tgcggaaaga gctggaccag atacctcagc tcccagagcc aaatcttctt tatagagctc
    13261 attgcgatag gtcgcaaatt cataaagtcg ttcaatatcc tttgcatcaa agagcccagc
    13321 ttgattcggc ggaatattaa gcaagagtgg agttcctcgc cctactgagt gaaagtagat
    13381 ttcgaccaac tcctcgagag acttaggatc ctgatcctca tggtagaacc agcctggacg
    13441 gatggaaaca tctgcctctc cgattgaaaa aatcgtgccc gagggatccc cgtgctgaag
    13501 atagttcagc tctgcttctg ttcctagttt atcaggattc accttttgcc acagtggatc
    13561 acctgcatac cctcgttcat tgccaatcca gcggatactg gtgccttctg ttgaaaaaat
    13621 caagcaagcg ccctgcaggt cacgaatggt ttcaaaccat ttttcaaatt cataattaac
    13681 cttttgcgcg ccctctcctc tggcaccatc catccaaacc tcagcgaact taccagcatt
    13741 cccatagtta ggatttgata agatttcctt caactgagcc agataatagg cattgtagtc
    13801 cgcttctcgg tccacatgat agaggggact atgggcatcc cacggtgaca ggtagacccc
    13861 catatccata tcaaactctg tggcagcttg ggatacttca aggagcaagt cgccctttcc
    13921 tctcctccaa ggactgacct taaccgaata atctgtgtga gctgtcggat aaaggacaaa
    13981 gccatcgtgg tgcttgacca ccaaaatcaa ctttttgaag cccgtttcct tgagcacacg
    14041 aacccactca cgcgcatcca actgactcgg gttaaagcgc tcaggatcct cctgtccagt
    14101 cccccattct tggtcataaa aggtattaga accgaagtgg ataaaagctg ctagttcatc
    14161 tcccagataa gctagctgag tctgacttgg taacggtcca tgcggtttga ttttcttcat
    14221 cgttatatat ctccttcttt agcaacttct cttgttcaca aggttatcca caggttgtgg
    14281 ataataaacc atgatctaac agccagctct ttccaactcc aactggtagg ctcaggattt
    14341 ttctcctcaa tattccctct tcaaacagct ctgtcatatg gttctgctaa cacctctcag
    14401 aatgctactc tccataatta ttctcaggct tctttcaggt cattgtgtga agaccattca
    14461 ctctccagac ttttccacag attgtgaata agtgattatt ctaaactatc acctcgtcga
    14521 ctataacaaa aaataaaaag agggtcaata agataattat ctcttcctaa atactcagaa
    14581 aagattctat aatttgtaca attgaacaag aaatgcttct ccaaaatcta tcttcaaaag
    14641 aatgttgcat ctttttatcc tttcacacaa acatttctct ttatacagat ccaagtgata
    14701 accagatgat aattggacac tttttggtca tttgtatatt ttttgaaaaa ttttttaaaa
    14761 aaattttata tcctttttat agaagtttat gcatttgtat ctatgtattc tatcctatgt
    14821 tatgtataat aacataaaat tgtgctaaat attataattt atattatttt ccgagaaatt
    14881 atagccattg acattaccta ggaattgcgt tataacatac atgtaagcgg tacccaaaat
    14941 ggtgccaagt caaaattttt aaggaggaaa atacatgtct tcacatccaa ttcaggtctt
    15001 ctcagaaatt gggaaactga aaaaagttat gttacaccgt ccaggcaagg agttagaaaa
    15061 cttgttgccg gactatcttg aaaggcttct ttttgatgat attcctttct tggaagatgc
    15121 tcaaaaagaa catgatgcat ttgcccaagc tcttcgcgat gaaggaattg aggttctcta
    15181 cctagaacaa ctcgctgctg aatcattgac ctctccagaa atccgcgatc aatttatcga
    15241 ggaatactta gacgaagcca acatccgtga tcgtcaaacc aaggttgcta ttcgtgaatt
    15301 gcttcacggc atcaaggaca accaagaatt ggttgaaaaa acaatggctg ggattcaaaa
    15361 agttgaattg ccagaaattc ctgacgaagc taaagatcta actgacttag ttgaatcaga
    15421 ttatccattt gcaattgacc cgatgccaaa cctctatttc actcgcgacc catttgcaac
    15481 aattggaaac gccgtatcgc ttaaccacat gtttgcagac actcgtaacc gtgaaacact
    15541 ctacggtaag tatatcttca aataccaccc aatctatggc ggaaaagtgg atttggtcta
    15601 caaccgtgaa gaagatacgc gtatcgaagg tggagacgag ctagttcttt ctaaagacgt
    15661 ccttgcagta ggtatctctc aacgtacaga cgcagcttct atcgaaaaac ttttggtcaa
    15721 catcttcaag aaaaatgttg gcttcaagaa agttttggcc tttgaatttg ctaacaaccg
    15781 taaattcatg cacttggata ctgtcttcac tatggtagac tatgacaagt tcactattca
    15841 cccagaaatc gaaggcgacc ttcacgttta ctcagttact tacgaaaacg aaaaacttaa
    15901 aatcgttgaa gagaaaggtg acttagctga acttcttgct caaaaccttg gtgtagaaaa
    15961 agttcatttg attcgttgcg gtggtggcaa tatcgtagca gctgcgcgtg aacaatggaa
    16021 cgacggttct aacactttga ccatcgcacc tggtgtggta gttgtttatg accgcaatac
    16081 cgtgaccaat aagattttgg aagaatacgg gcttcgcttg attaagattc gcggaagtga
    16141 attggttcgg ggccgtggtg gacctcgttg tatgtctatg ccatttgaac gtgaagaagt
    16201 gtaatcgctg ttcggcattc gtcaatagaa aatgtaaaaa atagaaagag gaaataataa
    16261 aatgacaaat tcagtattcc aaggacgcag cttcttagca gaaaaagact ttacccgtgc
    16321 agagttagaa taccttattg gtctttcagc tcacttgaaa gatttgaaaa aacgcaatat
    16381 tcaacaccac taccttgctg gcaagaatat cgctctccta tttgaaaaaa catctactcg
    16441 tactcgtgca gcctttacaa ctgcggctat cgaccttggt gctcacccag aatacctcgg
    16501 agcaaatgat attcagttgg gtaaaaaaga atctactgaa gatactgcta aagtattggg
    16561 acgtatgttt gacgggattg aattccgcgg attcagccaa cgtatggttg aagaattggc
    16621 agaattctca ggcgttccag tatggaacgg tctaactgac gaatggcacc caactcaaat
    16681 gctcgctgac tacttgactg ttcaagaaaa cttcggtcgc ttggaaggct tgacattggt
    16741 atactgtggt gatggacgta acaacgttgc caacagcttg ctcgtaacag gtgctatcct
    16801 tggtgtcaat gttcacatct tctcaccaaa agaactcttc ccagaaaaag aaatcgttga
    16861 attggcagaa ggatttgcta aagaaagtgg cgcacatgtt ctcatcactg aagatgctga
    16921 tgaagcagtt aaagatgcag acgttcttta cacagacgtt tgggtatcaa tgggtgaaga
    16981 agacaaattc gcagaacgtg tagctcttct taaaccttac caagtcaata tggacttagt
    17041 taaaaaagca ggcaatgaaa acttgatctt cctacactgc ttgccagcat tccacgatac
    17101 tcacactgtt tatggtaaag acgttgctga aaaatttggt gtagaagaaa tggaagtaac
    17161 agacgaagtc ttccgcagca agtacgctcg ccacttcgat caagcagaaa accgtatgca
    17221 cactatcaaa gctgttatgg ctgcgacact tggtaacctt tatattccta aagtataatt
    17281 ttagataata aaccgtctac caacagctat gagggctgcg actaatagct ttagtccggt
    17341 cctcttttat gtaatggtaa tctattattt cttataaaat atgtgaaaaa tcattaaatt
    17401 gaaatctaaa cgcattctat tgagtgtgat aaaggagaat ttatggcaaa tcgtaaaatt
    17461 gtagtagctt tgggaggaaa tgcgattctt tcttctgacc catcagcaaa ggctcaacaa
    17521 gaagctttag ttgaaacagc taagcatctt gtaaaattga ttaaaaatgg agatgatctg
    17581 attatcactc acggtaatgg acctcaagtt gggaatctct tgctccaaca tttggcatca
    17641 gactctgaaa agaaccctgc cttcccactc gactcacttg tcgctatgac agaaggtagc
    17701 atcggtttct ggttgaaaaa tgctttgcaa aatgctctct tggatgaagg catcgaaaaa
    17761 aacgttgcct ctgttgtaac gcaagttgtc gtagataaaa atgatccagc ttttgttaac
    17821 ttgagtaaac caatcggtcc tttctattca gaagaagaag caaaagcaga agccgaaaag
    17881 agcggagcga ctttcaagga agatgctggc cgtggctggc gtaaggtcgt tgcctcacca
    17941 aaacctgttg acatcaaaga aattgaaacc atccgtactc ttttaaatag tggtcaagtc
    18001 gtcgtagctg caggtggtgg cggtattccc gtcgtcaaag aaaacaatgg acatttgact
    18061 ggtgtcgaag cggttattga taaagacttc gcttcccaac gtttggcaga attggttgat
    18121 gcagacctct tcatcgtttt gacaggtgta gattatgtat ttgttaacta caacaagcca
    18181 aaccaggaaa aattggaaca tgtgaatgtt gcccagctgg aagaatatat caaacaagat
    18241 cagtttgcac caggtagcat gcttccaaaa gtagaagcag ctatcgcttt tgtcaatggt
    18301 cgtccagaag gaaaagcagt tattacttcc cttgaaaatc taggcgcctt gattgaatct
    18361 gaaagtggaa caattattga aaaaggataa gttgttttac taataagatg tattctattt
    18421 ctagtatctt tatatcaaat tagaaattat tcttgaaaac atgtacaata tttcaaaaga
    18481 tattagtttt ttagacttta atatggtaaa acaaatataa atagaaagcg ttttcttaaa
    18541 tgtttattta agaaagtagt tggtttttta cactttgtta gacatcagga ggaaaaacaa
    18601 atgagtgaaa aagctaaaaa agggtttaag atgccttcat cttacaccgt attattgata
    18661 atcattgcta ttatggcagt actaacttgg tttatccctg cgggggcctt tatagaaggt
    18721 atttacgaga ctcagcctca aaatccacaa gggatttggg atgtcctcat ggcaccaatt
    18781 cgggctatgc taggtactca tccagaggaa ggttcgctca ttaaagaaac gagcgcagcg
    18841 attgatgtag ccttcttcat ccttatggtt ggtggtttcc ttggcattgt caacaaaact
    18901 ggtgctcttg acgtagggat tgcctctatc gtgaagaagt ataagggccg cgaaaaaatg
    18961 ttaattttgg tactaatgcc tttgtttgcc ctcggtggta caacttatgg tatgggtgaa
    19021 gaaacaatgg ccttctatcc actccttgtg ccagttatga tggccgttgg ttttgatagc
    19081 ctgactggtg ttgcaattat tttgctcggt tctcaaatcg gctgtttggc atctactctg
    19141 aatccatttg cgacaggtat tgcttcagcg actgcgggag ttggtacagg ggacggtatc
    19201 gtacttcgtc tgatcttctg ggttaccttg actgctctta gtacttggtt tgtttaccgt
    19261 tatgcggata agattcaaaa agatccgact aagtcactgg tttatagtac tcgcaaagaa
    19321 gatttgaaac actttaacgt agaagaatct tcatctgtag aatctacact tagcagcaaa
    19381 caaaaatcag ttctcttctt atttgtgttg acattcatct tgatggtatt gagcttcatt
    19441 ccatggacag accttggcgt taccattttt gatgacttta atgcttggtt gactggtctt
    19501 ccagttattg gtaatattgt cggttcatct acttctgcac taggtacttg gtacttccca
    19561 gaaggcgcaa tgctctttgc ctttatgggt atcctgattg gtgttattta tggtcttaaa
    19621 gaagataaga ttatctcttc cttcatgaat ggtgctgctg acttgctcag tgttgccttg
    19681 atcgtagcga ttgctcgtgg tattcaagtt atcatgaacg acggtatgat taccgataca
    19741 atcctcaact ggggtaaaga aggcttgagc ggtctatctt cacaagtctt tatcgttgta
    19801 acttatatct tctatctacc tatgtcattc ttgatcccat cttcatctgg tcttgccagc
    19861 gcaactatgg gtatcatggc tccacttgga gaatttgtaa atgtccgtcc tagcttgatt
    19921 atcactgctt atcaatctgc ttcaggtgtc ttgaacttga ttgcaccaac atctggtatt
    19981 gtgatgggag ctcttgcact tggacgtatc aacattggta cttggtggaa attcatgggc
    20041 aaactcgtag tcgctattat tgtagtgacc atcgcccttc ttctccttgg aaccttcctt
    20101 ccattcctat aaaatagtga gtgaggtgat tccatgaaaa tagatataac aaatcaagtt
    20161 aaagatgaat ttcttatatc attaaaaacc ttgatttcct atccttcagt actcaatgaa
    20221 ggagaaaatg gaacaccttt tggacaagca atccaagatg tcctagaaaa aactttagag
    20281 atttgtcgag acataggttt cactacctat cttgacccta aaggttatta cggatatgca
    20341 gaaatcggtc agggagcaga gcttctggcc attctctgtc atttggatgt tgttccatca
    20401 ggtgatgaag cagattggca gacaccgcca tttgaagcaa ctatcaaaga cggctgggta
    20461 ttcggacgtg gtgtccaaga tgataaaggc ccttcgctcg cagctctcta tgcagtaaaa
    20521 agcttgctgg accaaggtat tcagttcaaa aagcgcgtac gctttatctt tggtaccgat
    20581 gaggaaaacc tctggcgctg catggcacgc tacaatacca tcgaagaaca ggccagtatg
    20641 ggctttgcac ctgactcatc ttttcctctg acctatgctg aaaaagggct tctacaggtc
    20701 aaacttcatg gcccgggatc ggatcaacta gagcttgaag taggaggcgc ctttaacgtt
    20761 gtaccagaca aggccaacta ccaaggtctt ctctatgaac aggtttgtaa cggtctcaaa
    20821 gaagctggtt atgattacca aaccactgaa caaaccgtaa cggttctcgg agtgccaaag
    20881 catgctaagg atgctagtca aggtatcaat gctgtcatcc gactagctac cattcttgct
    20941 cctctccaag aacaccctgc tctcagtttt cttgcaacac aagcaggtca agacggcaca
    21001 ggaagacaaa tctttggtga tatagcagat gaaccttctg gtcacctatc ctttaatgtc
    21061 gcaggtctca tgatcaatca tgaacgttct gaaatccgta ttgacattcg gactcctgtc
    21121 ttagctgaca aggaagaact agtagagttg cttacaagat gtgcacaaaa ctaccaactc
    21181 cgctacgaag agtttgacta tctagcgcct ctatacgtcg caaaagacag taaactcgtt
    21241 agcacactga tgcaaatcta ccaagaaaag actggcgata acagtcctgc tatttcatcc
    21301 ggtggtgcca cttttgctcg caccatgcca aattgtgtag ccttcggcgc cttattccca
    21361 ggagcgaagc agacagaaca tcaggcaaat gaatgtgccg ttctagaaga tttgtaccgt
    21421 gctatggata tttatgccga agccgtctat cgacttgcaa cttaatcagg caactgtttc
    21481 tacaaaaaaa aatcgaccga ttaatgaact gcaccccaaa agttagacag aataaatcta
    21541 acttttgggg tgttttatta tgaaattgaa ttatgaagat aaagttcaga tctatgaact
    21601 aagaaagcaa ggacaaagct tcaaacagct ttcaaaaaga tttatgtgga tgtttctggt
    21661 ttaaagtcat ctgaatcttt gagatgagct ttataaatcg cttttttcag tgtttgcact
    21721 ggtgtttcga taaactcaaa ctttttagcc gtggtattgc ctgattttat agtatattga
    21781 aactagaata gtacacctct acttctaaaa catttttaga aatcgatttg tcctgttctt
    21841 atttcatttt actatatttg agccacttcg tctttaacgg ctttattcat aagctcttgt
    21901 aatttttctt tactatcaat tacttctgat tttccgttgt aatttattgt aataggtttt
    21961 aacttaccta atttctcgac acgctcatta atttgatctt ttttgaaggc tgcatatgtt
    22021 tttcctaaga ttttttcgaa aatatattta tcagatagcg gtttgccttc ttcttcagct
    22081 tggtttttgt attgatttga aacataagga acaaatcctt catagtaacc taatgctccc
    22141 ataagttcaa aagcttgttt tctaattcaa accattgcaa ctcagatttc agcttttcag
    22201 ataaatcctg ctcatccaaa taatgactta aaattagtgc tgaactcgtt tctgtatcct
    22261 gtacaggctg atcacccata ccatcaaaaa ataaactcgt tcctagcaag accgaacaag
    22321 ctcctattgc atatggcctc aaagaaaaac gctgctttct ctcaaattga aattctttca
    22381 tcccatctcc catcattcat tattactgta tattttgtat atcagaaata gtttgtattc
    22441 acaaatcttt ctagttattc ccttatcatt cctaattaag ggagataaca tacaataatt
    22501 tttagttaaa tgtatatcga tgttttttgt ttttcttaat aaacgcaata caaaaagagc
    22561 ctgttgccaa gctctttgta ctcaatgaaa atcaaagagc aaactaggaa actagccaca
    22621 ggttgctcaa aacaccgttt tgaggtagta gataagactg acgaagtcag ctcaaaacac
    22681 tgttttgagg ttgcagatag aactgacgaa gtcagtaaca tctatacggc aaggcgacgc
    22741 tgacgtggtt tgaagagatt ttcgaagagt attagtctat tatttcttct cagcgcgaag
    22801 ggctgacaag atttgtgttc ggatatcatc cacaccattt ggagtatttg gtaaaaagat
    22861 ggtttgattt cctttagagg caaaggtatt caaggtatcc aaatactggt tggtcaagag
    22921 gatagacatg atttgttctt ctgtcatgcc aacattggct tccttgagtt cggtgataga
    22981 ctctgccaat ccatccacaa tcgccttacg ttgttgggca atccccacac catgaaggcg
    23041 gtctttttct gcttcggctt cagctgcagt gacaatttta atcttgtcag cttccgccaa
    23101 ttcttgtgct gcgacccgct tacgttgcgc cgcattgatt tcattcatgg attgcttaac
    23161 ttctgcatcc ggttcgactt tggtaatcaa ggttttcacg ataatgtagc cgtaagtggt
    23221 catttcttct gctacttggt gttgaacctc aagggcaatc tcatcttttt tctcaaacaa
    23281 ttcatccaag gttaattttg gaacagaaga gcgaagagca tcttcgatat aagatttaat
    23341 ctgagattct ggacgtatga gtttatagta agcatctgtc acgctctgct cgttgacacg
    23401 gtactgagtc gctacattca tcataacgaa cacattgtcc ttggtcttag tctcaaccac
    23461 aatatcactt tgcaacaagc gcaactgaat ccgtgctgca atcgagtcaa tcccaaaagg
    23521 caagcgaata tgaataccgc tattagcaac cttttggtat ttcccaaagc gttcaataat
    23581 cgccaccgac tgctgacgaa ccacataaac tgtactcagt gtgactatca ccaataggag
    23641 cacacaaaca atcagaaaaa tcatgaaaaa tattgccata atggaacctc cacaagtatt
    23701 tttctagtat tatagcacat ttaaagaagg ctgtgccgtt tttactgcga tttttcctga
    23761 aatgtcaata attagaggtg aattgtccta ttgtcgtcca atctcttgct aaaataactc
    23821 tttataaaag gcaatcgttt cttctaaggt tggcataaat ggatttcctg gtgcgcaggc
    23881 atcaatcaag gcattcttag aaaggtattc aaagtcgaaa tctttttctt caataccaag
    23941 ttcagtcagt ttcttaggaa tacctactgt ctcagaaagc ttctcaatct caacaatcgc
    24001 ataatcggca cattcttgat ctgatttacc ttctacatga agtcccaagg ctttggcaac
    24061 attgcggaaa gcttctggta cacgtttagc attttcacgt tctataactg gtagcaacat
    24121 ggcacagcaa acaccatgtg gcaaattata tactgcaccg agttggtgag ccattgagtg
    24181 aacataacca agaccagcat tattaaagct cataccacca aggaagatgg cattgaccat
    24241 accttcacgc gcttcaatat catgtccatt ttctacagca cgaggaagat attccttgat
    24301 aagctcaata gcaccaatag acagtttctt ggttacatca taagcaccag gtgttaccaa
    24361 agcttcaaca gcgtgagtca gagcatccat accagtagca gcagtcaggc ctttaggttt
    24421 ggaaagcatg agttccgggt cattaacaga gataagagca aggctattct tgtcaaccat
    24481 taccatctta accttgcgtt cttcatcagt aatcacatag ttaatagtga tttctgcaga
    24541 agttcctgcc gttgtattga tagccacaac tggcaagcct tttttagcag acttatgaag
    24601 cccttcataa tcctgtggtt ttccaccatt tgtagccatg atagaaatac aactagctgc
    24661 atcctgtgga gaacccccgc caagactgat gataaagtca cagccatgtt cttgcaaagc
    24721 agctacccca tctgtgacat ttttacaagt agggtttggc tctacatcgc taaagatgac
    24781 atattcgatt ccttctgtat ccagtggttt taaaacctta ggtaaaatgt cactgccttc
    24841 gatgtactta tctgtcacca aaagtgcctt tttatagcca agttccttga tataaggacc
    24901 cacttcattt acaacacctt taccaataag gttgactgcc ggaacataaa atgtagccat
    24961 ataattttcc tcctgcgcct ccgcgctatc tatttaacat cattatatta gtttttgtat
    25021 tcgttttcaa ttatttgtga attgtttaac aaatcttttt aaaaggatag gagggacata
    25081 agttcacctc ctatatacac aatttttatt tatgtagcgg tcccaacaac tgacatgcac
    25141 gatagtctgc tgattctaga tcttctgttc caaataagga ccaattttta ggtctaaaga
    25201 tatcttcctc gggtacatta tgcatattga caggaattct caacatagaa gccaaggtaa
    25261 tcaagtctgc tccaatgtgt ccatatgtta tggctccgtg attagctccc caattattca
    25321 tgacgtcata gacagacttg aaagcacctt ttcctgtcaa acgtggagca aaccaagtag
    25381 ttggccatcc tggatctgta cgattatcta aagtatggtg aacatcttca ggaagttcaa
    25441 gtgtataacc ttctgcaatt tgtagcactg gaccaacccc ttttagaaga ttgagacgta
    25501 ccattgttac tggcatatcc cccttcgtca agaaacgagt tgagaatcct cctccacgga
    25561 agtattcgcg gtttgctggt gggaagtctg tattttcaag catagcctgc acttcacttt
    25621 cttccaactc ccagaatggt ttcataacag gtttgccatc tcgagtagct tgccctgtac
    25681 catccaatgt acaagaacca gagttgatta gatgtaagaa gccagctgca gcacaaccct
    25741 ctaaagtatg tcccgttaca cgtttaacag cctctggact ccaataagtg cgcacatcag
    25801 caaagatttg tggagtattt gttaatagat aattaaagag catagacaca ccatttagtg
    25861 aatcattctc tgtcgcaaat acaaatggtt ttcgaatacc attccagtca aactgagtat
    25921 tgaggaaagt ttccataaag tccccatttg ggaaatggtc tgtccactga cgttgacctt
    25981 ggaaaccagc tactaaagca tggtgaccaa ctgcttcttc ctcaaaacca agttcagcaa
    26041 gtcttgggtt accaaccatt aagtcacgtc caatcatgaa catcttaata acaaattccc
    26101 attgtctatc tttttcttca cggcttaaaa caaggtcttc acggttatgg tcgaatcctt
    26161 cttttacgtt ttctttcacc catttgagcg cacgttcgaa ctcttcaggg tcgtaaatac
    26221 cacggtccat acggcgtgtg aactccgtca tatctaccga ttcatttcgc attcctaggt
    26281 attcttggaa gaaatccgga tttacaatag aaccaccaat ccccatcgaa acactcccca
    26341 ttgataagta agctgtatct ctcatcaagc cagttgcaag agctgcccgc gcataacgta
    26401 aaagtttttc tttgacatct tctggaatag ctgtatcatt agcttcctga acatctctac
    26461 cataaatccc aaaggctgga atcccttttt gagcatgtga agctagtaca gctgcaagat
    26521 agacagctcc tgggcgttct gtcccattaa atccccaaat agcatgagga atatctggag
    26581 acatatccat agtttcacta ccataacacc agcatggtgt aactgtaatt gttgcgcaaa
    26641 catttgattt tttaaacaac tcatgggaag ctgcagcctc tggaacacga ccaatggtag
    26701 atggagaaat cacacattcc acaggttccc catctggata tttcaatgtg cttgaaatca
    26761 aatctgccac acttttagcc atgttcattg tttgtacttc aagtgattcg cgtacacctt
    26821 gacgacgacc atcaatagtc ggacgaatcc caatacgtgg atgttgaatc atactatttt
    26881 cctcttattt ttctgtttct ttcatactac cgatgataat ttttaaaatt acttataagt
    26941 ataaacctct acctctgcca aacttaaagg aattcctgcg tttctcaaag aaattctaac
    27001 cttttttccc ttcagccctt ttaagtctat ggatagatta ttgctttcta aactgtcaat
    27061 atgttgttta aaaacttcat gattatttga atcatatata ataatatcaa aatttgataa
    27121 tctctgaatt tcagcatctg ttctattata aataattaac ttttctaatt cttcggtttg
    27181 tgctaaatct atctcccacc atgaaggaga atctcctttg gtatgagtca ctgaatgatg
    27241 accataatct ccgtttttat ttccatcaac tgctagacga gaaaaaccat tgtaatccgt
    27301 tgaactctgt cgagtttctt tggttaatgc aatattagaa agtttcttcg gagttctctt
    27361 tgaaccatag acttcaactt ccgctaaact taacggaata gctgctgatt ttaattctat
    27421 tttgactagc ttagccccta cagaaggtac ttttaaagat aacaaaccat caactacttt
    27481 atcaaaatgt cttctaaaaa cttcttctcc tgatgaagat agaaaaataa catcaaaatt
    27541 agataaacgc tgaggttcgg catctgttct attataaata tcaactttag aaaccgtaaa
    27601 ctcttctccc agatcgacct gccaccaagc gttagaatct gccttagtat gagtcaccga
    27661 atgatgtccg taatctccat ctttattacc atcaactgct aaagcagcta caccctcata
    27721 attggttgaa ctttgagtag ctaccttatt tgtagagact actttatctt ctgttatttt
    27781 atctatatcc tcttcagatt gcttaccatc tgattctcta aaaacctcta cttctgctaa
    27841 actcaaaggc actccactcg ttagtaattt aactttaata taccttgctc ctttttcttt
    27901 gaaatctaga ctaacagatt cacccgacaa attattaaca tgtttcttag caacttcgtt
    27961 tctattattg tcatatagaa tcacatcaaa attagataga cgttgagtct cagcatctgt
    28021 gcgattataa attttaacaa gcccaacttt atccattttt ttcaaatcga cttcccacca
    28081 agagggatta tctgccctag tgtgtgttac cgaaccagag ttaaaattac catttctgtt
    28141 accatccaca gctctattag ggtctccatt gtaatctaca gaactttgtg ttgttggttt
    28201 tgcatatgct atattcaaat taccatcatt aaatttatct ggtgttggga aagagactgg
    28261 acctgtcccc tcagtattta tagacatctc taccattcca ttatgattaa ccgtaatggt
    28321 ataaacatgg gtattctcat cccaattttc tgtataagta taatgatttt tatcgccact
    28381 tatatttatc tgaggtttat gaccagtatg cccttttaat gtaagtgttg ttgtcctaaa
    28441 gtcattatct acaggattga tggaataatt tttgcttatc cagttcgcta actctaattc
    28501 ttctttcttc caactttttg atgcatcaaa atttcctgat aatgcccaca tagctgtctt
    28561 atctgtcctg taattattca ataaaatatg taaattattt ggattttctt taacaacagc
    28621 gtaagtatgt ggcgtcaaat ctaacgataa cgactttgta ttattagtat acataggcaa
    28681 cattacttgc tgatttttat tgatattagc attactatta taaatatacc aggaattacc
    28741 tacacgctga gcatacccat ctccttcata aagttttgga taaagcgagt ttaaatagtt
    28801 gactttacta gacaattcct cactattttt agtcaaaatt tttgcattag ggaatataga
    28861 tgaaatcttt tccttatcaa ttttctcatg tattacagga agaatatgat atctcccatt
    28921 attatataaa ggcattgttt catcattcga ataaagtcct tgataaaatc cgtttaatga
    28981 actaatccta ccttctccat tccaaaatac agcttttgtt ctatttacaa cttcttcctt
    29041 acttggagct ggattttgta tagcatgtct aaagaaagga ataatacctt tagtaaatgc
    29101 tggagttggt acatcatttg tcataaatgt atacgcggca cattcgaaat tataaactgt
    29161 gcctccccca gtatatacat tcatcatttc catagcaatc attgattctg gttccgatgc
    29221 ataggatctc atatccctag ctcttccagt ttcaaatgtg tttgtataat gtttttccca
    29281 ccatttccat gtatctgttg atgagcccca gttatcacat aagccactca accaaaatcc
    29341 actaacgata gaatctgtac ccgcatcatc tcttattggc gtatttttag ttgccaacac
    29401 caaattttta tgatattttt gactcgcttc aaagaatgtc ggatcattca taatagtttc
    29461 ccagaaccat ttttcatgat catgccagat aaaatgcgct ccatatttgg cacaaacttc
    29521 caaatattta gcactatgcg gagctaactg gttattgtaa atccaataat tctcaatatt
    29581 taaaacacct tttaacacac tatacttttg gaattgttca tctaaccact ctggaggaac
    29641 tgtattacgc tctccagccg acataataac caagaaaact ggaatgttta gactttgagc
    29701 ttcctccaac atcttgacat accattctct caattctttc gtatctcgtg gaatacaact
    29761 tgttggttta cagacttttg caggatgaag ttcaatcgct gcatatggtt ttacatcttc
    29821 aggaatagct tcccatgctc ccttcaatgt gttcccccac cataatccgt taccattatc
    29881 attgccatac aacggagaaa gcaacaatgg cgattcatta ttaatcgtcg ttctcatttg
    29941 aacacgatta tcagccttaa ctcctgctaa caatccaaaa cataacatcc caatacatac
    30001 aaacagtatt gtgattaatt ttctttttat tttttcttta ttcatgactt atacctaaaa
    30061 atttaactca ataatttttt ctgaattaaa taccaattca atattttgta catcagtatt
    30121 tttgccatat actcttactc ttactttttg atctttgttt cctccttcca attttaggaa
    30181 tgttatatcc ccatttttcc aagcaaacga taccttatat cctcctctta ctctgaaacc
    30241 tttcacttct ccttctgacc aagcagaagg taaagctgga attagtgata accaattatg
    30301 atggctctgt actaataatt cacaaattcc actcaccaaa cctaaattac catcaatttg
    30361 aaatggtgga tggtcaagaa ataaattgcc aagagtcgca ttatttaaca aaccattaat
    30421 ctggttataa gcaggttcac cttgatatag tctcgcaaaa aaatgaatca gccatgcagc
    30481 actccaacct gtttgtgtac tagcatgcaa accacttact aaccaattat taatcgcttg
    30541 ctccctatcc tgtgaagata aaaagttagc gtttgataat cttctattga tagtgatttt
    30601 agctgcttct gctaattccg gagttttatg aatatcaatc tcattataag gataaagccc
    30661 aaatagaggt gaaatgtgtc tatgaccagg ctctacttct tcataatcct ctagccattc
    30721 ttgtatttgc ccattactac ctatttttgt tctaggtaat ttctttttta actccttcac
    30781 acgactaata aaatccgaat tgtctcctaa ttgttttgca attccaatgc atgaatcaca
    30841 aaaatatctt aaaatttgat tatcaattgt agatgataga caagcatttc cttcaatacc
    30901 attttttaag cgatatttat tttccggtga gacacttgga cctgtcatca agtagccatc
    30961 cacctcaaat aaataatctt caaagaaaag aaatgcttct tttatcattt caaaatgttc
    31021 cgtaagaata cgctcatctt ggaaatataa atagtgttcc caaatatgag tacataacca
    31081 tggaatagtt aatacccaaa ttgcagcccc catggcatga gattggggag ccgtatcgcc
    31141 aaaaccatcc gtattatgat gtgctgtaaa acctctagct ccatacattt tcttagcggt
    31201 tagtcttccc ggttctctca ttctttcgag catatcaaat aatggatatt ctacttctgg
    31261 taaatcacat ggacctacca tccaataatt catttgagta ttaatattaa tcgtatattt
    31321 agaaccccaa attggattta attcatcaca ccatattcct tgaagattgg caggtaaacc
    31381 attcggttga ctagacgata ttaacagata tcttccataa tgaaataaca agttagtcaa
    31441 gtagttacta tactttttag tgttttcaag aagtagattc gttggaatgc taagacaatc
    31501 tttactatag tctagtttaa aatcaactct attaaattgc tcctgatatt tttttacatg
    31561 ttcatctttt tctgtaaagt aatcaatact actaaattct ccctgaagag aagaaatatc
    31621 tatatttccc caataatccg tcattgattt gagataaaga aatacctctg tagcattccg
    31681 aataactatt gtctctccca atacacttac ttcaccatcc gtaaccttag aatgacatac
    31741 tactttaaac tgaacacctt ttctacctcc agcagaggcc gacattaaaa ttgtacttga
    31801 atccagttta gatacttcat cattaaaccg tttatttcta cccaaattaa tgtttaaatt
    31861 taatgtgttt tgaactgatg acactatacg gcaacataaa atattcttat taaaactcgt
    31921 aaaatattct ctttttattt gtaaattaca actattaggc tcaaacacaa cattagaaat
    31981 agctgtatct aaatctagct ctctttcata caatgaaaga gcacaagact gaatatctat
    32041 atgctcaatg taaagttccc caagtaattc atagtggctt tgatctcttg gggtagcaaa
    32101 cattgttaac tttatcaatt cttcggcttt ctgaatttct ccatctaaaa gatattcccg
    32161 aattttttta agatgcaata gtgagtctgg attatttcta tctgactttc ctctatacca
    32221 aatagtctca tcgtttagtt gaatacattc ttttgtagct gaaccataaa tcataccacc
    32281 taaatgaccg ttcccaatcg gcaaggcttc attccaattt gaggcagctt tcttatacca
    32341 taatttcact ctttacctct cttccaaaat ggaggtgata tcccaaatac cacctccaca
    32401 ctttctacta cttcaaaatt cctaaaacaa ctaggataac tccaatagcc ataacactaa
    32461 agattagtac aaccggattc tttccttttc taattaattt acacattaat aaagtcaaag
    32521 ccatagggat aaatcctgga attaattttg taatcatttc ttgaacagaa ataacaagtt
    32581 ccccctgctt aaattctaat ccaaaattaa taccaaccat tgatggaatc aaaccaccca
    32641 ctagtactag ccctaatgct gtcgccatac tcgtaacgcg attcaatgtt ccttttgtat
    32701 tattttcttg gataagacta gaacccttag tatacccata tttcaaaccg aaatatttaa
    32761 caggaatatt aataatatta aacaatatta aggcgataaa gatacctaaa gcaccgccgt
    32821 ctttagaata agacgcacca atactaaaac agataggaac tagtgtcagc cagaacaaac
    32881 tatctcctag accagccagt ggccccatca agccaacttt aataccagta attgaagctg
    32941 caccttcatt tccttcttgt tcttccatag cggaagtaac tccaagaata aatggtgccg
    33001 ctgtttgatg agtattgaaa aactcaaggt gacgtttcat tgcaggagaa gctgaatctt
    33061 tgtctgggta tagttttttc aatactggaa gaattgtata tagaaaacct aggttctgca
    33121 ttctctcata gttccatgaa gaaccataca taaaacttcg tttgaaaact tttttaagtt
    33181 caactttagt tactttatta ttcatcatag atcaagatcc tcctcaacat cactacttga
    33241 agttgtttct tgtggtttac ttccaatcat atcgtagaag tatgctaccg caataccaac
    33301 tagtgagatc ccaatggttg acattcctcc atacacagaa caaatgaatc caatcaacaa
    33361 gaatacccac atatttttct tgagcatcat atttaaaagc ataccaaaac caattgaagg
    33421 tagtaaagca cctgcagagt taagtccctg cataacgatt ggtggaacct tcgcaaacaa
    33481 gtctgccaca tattcccctc caagcataat agctaggaaa attggtacaa ttttaaataa
    33541 cgtgattaaa accaaacttg aataatgata aaaaccgatc tttgaataat ctccgttttt
    33601 agcatcatta tcagcttttt tcacaaaata aacatctaaa gtttttgcaa gaacatccaa
    33661 ctgttgggta gcaactgcaa ttggaactgc tatagcgata ccagcagttt ctccttgacc
    33721 agataaaata ccaaatgcag taccaataat cgcacctgaa atagtatctg gtggagtgta
    33781 acctccaata cctgttacac cgagccaagt taattcaaga gctgaaccaa taagaacacc
    33841 ttgggtgaaa tctcctaaga ctaagccaac cattgcactt gtaactaacg gacggtgaat
    33901 cataaataac ggtccattat agtcaatagt ggcaataatc ccaactaatg tcaccagtaa
    33961 tgcttgtgtg aatagcatat actgtacctc cttaaattat ttttataaaa atttttccaa
    34021 cattgtaact ttatcattag gaaccatttg aatttcaact ctcgttccct tatcaactat
    34081 tttcttaaaa taatatttgt cttcttcacc tagagctaca cctcccgtta ccttttcatt
    34141 ttcctccgtt ttactcatct gtcctacatt gaggtactcc aattttaaat ttccttcaat
    34201 agaatcatac acatcttttg gatttgtata tatcagcatt gttctctttt ttattggcac
    34261 agagtttaaa acttccacaa accgttttac actaaagaaa acaattttta aacctactgg
    34321 tgcagaaatc tttaaaatag attgtcgtgt tttatcttct gagatgcgat cattaacaat
    34381 gataacttgc tcaatatcat acttttttag ccacgtagtg acaacttgac catgtaccag
    34441 acggtcatca atacgaacaa actctataga cataaatctt cttcctcctc tacgttaagt
    34501 tgttgtttaa cattaaacaa actattttga gcattgtgaa caatttcttc taaattgatt
    34561 tttgaatcat aatttgatat taattccact aggagaggga tattaaaccc tgttacaata
    34621 tcaactgaat ccaaatttaa aaaccgtgac aaagcaacat tattaggact tcctccaatc
    34681 aagtcagtca aaacgataac ctcttgattt gagtctaaca gttcatttac ttgattttta
    34741 aaataatgtt caaactctac aatattctct ccaggcatca aacctaatgt cctaactcta
    34801 tcatttgttg tctcaccaac aaacatttct gcggtcatga gagctccgct agcaaaatta
    34861 ccatgactgg caactaaaat tcctctatta aacattttct ctttcaacaa ctactccttt
    34921 cttaaggata atattagcat aaagtgaagt ttctcctgta gcaacaatag cataagcttt
    34981 cttactacgt tcataaaagt cttctcttct aagataagta atcgttttaa gatctgtacc
    35041 atgaccttca atcatctgtc tataggtacc ccatatctta ggaatatcat cacccgaaac
    35101 aacgttcata aactgaattg aactatcgac gtaactatct aatggcatta aatacagaat
    35161 ggaatctaat aattctggaa tatttacacc atcacaacga attagcttat ttgcacatga
    35221 ggcagaagga taattcgcgt cagctaatac tatttcatct ccatgtccca tttccattaa
    35281 agtcttcaat aaatctggag aaatattttt cggtatatgt tttaacatta atatcctccc
    35341 tattttctct gaccgtatgt tttaaatttt tctgccatta aatccatctc ctcatcagga
    35401 agaactactg gctctccaaa attcttagct aaacaataaa tttttgcaca atattcaact
    35461 tcttcaacaa tattaaatgc attcaataaa ttttgtgcac ctgctaaaat tccatgattc
    35521 gctagtaaaa ctgctctacg accttccatt gctttagctg cattcacagc caattctttc
    35581 gtaccatatg ttgcatactc agctacccga acatctttcc ctgccactgc aatcatataa
    35641 tgactagccg gaagtggttc tctgagacaa gctaatactg ttgcataagt tgtatgagca
    35701 tggataattg catcgatatc atcacgagtt tgatattgaa tcaaatgcat ataccattcg
    35761 ctagatggca agcgttctcc ctctacaaca tttccattaa tatccatcac tacaatatcg
    35821 gattctttga tttcaaagaa atcaataccc gacggggtaa ttgccatcaa ttgtttttca
    35881 cgatcgaaaa cactgagatt cccacctgtt cctttcgtca aatctgtttc tactagcttc
    35941 ttgccatact taattaattc ttgttttaca tctgacattc ttgtcctcct catatcaaaa
    36001 cactaaatat ttttcaattc accaattatc cccccttctt gtacaaaact taagaagggg
    36061 gagggaggca aatttacaaa ctctcaatct ttttaattct tttgggagta ataactctct
    36121 aattgtagaa actcctcaat aacatggtga gcttcttcca tcccttttaa ttgtcccata
    36181 gctatgagct gcacaacaat attccccaca gctgtaccct cagtcgaacc tgtaagaacc
    36241 tctttaccag ttctatcagc aatcatttgg ttaaaataac tggctctagc acctcctcca
    36301 atcacatata tcctcttata aaccttatga gttagttctt ctagtaactc tatcgctttc
    36361 ctatacgttt cagctaggct ttcataaaca atcttaaata gttgtccatc tgtccactct
    36421 ctagtttcat gatgataagc tagatattct gtcaaagtct tgtgcatatc agattctgtt
    36481 gcaaattcag ttgattcagt atcaatcaga ggaagatttt ctttttcttt ctccaccatt
    36541 gtcctaatat catcaaaaga ataggctttc cctcttcgtt caaatgaacg tcttagttcc
    36601 tctatgatcc acaaccctgt acaattcttc agaaatgtaa tcactccatc tttaccgact
    36661 tcatttgtaa atccataact gaaggattcg gtagtaagaa tcggtgaagt aagttccact
    36721 ccaaccaaag accaagtacc tgatgaaata aataaactac cttctgtctt aggtactgag
    36781 acaatcgcgc ttgctgtatc atgactacaa acattcacaa caggaatatc gcctaaacca
    36841 tactcctttt ttatccttcc aagaacattt ccctctgaaa caatttcagg aagtaaagat
    36901 gaattcaatt caaatagttt taagatattc tgattccaat tttgactcct aggatcaaat
    36961 aattgagttg ttgaagcaat gcttttttct gtagcaaact tacctgtcaa gagataatta
    37021 aacaaatctg gcattaaaag aatcttattg gtcttataga aagagtcagg agattcttga
    37081 cgtgccttaa agagttgaaa caaggtattt atctccataa tctgatttcc tgtctctgaa
    37141 tacagttttt ctaattcagt catttcagat atttccttta acactccctt tgttctttca
    37201 tcacgataat gaacaggttg tgataacagc ttaccttcat tatcaatcag gccaaaatca
    37261 actccccatg tgtcaatacc gatagataaa atcttgtaac tagtattagc caagcggata
    37321 ctttcaagaa ttttagctag tagaaagtca acatcccaag ataaatgccc ttttactcta
    37381 ataggtagat tagaaaagcg atttatttct tccattacta gtttattttc agaaaggtaa
    37441 ccaacgattg ctcttccaga agtcgcacct aaatctattg ctaaaaccgc ttccattttt
    37501 cttctctctt cgtccttgat taagtttatt ataatcccca cattttattt tttcaatatg
    37561 tgaacgctta cttggataat gttcaaatgt taacccaata ttcataaaaa taattcaaat
    37621 tcctccaatt tgtgctataa tatagttgaa atgataaatt aggaggagct tatgataaaa
    37681 gatgaacgtg tacttgaatt gattgaaatt atcaaaaaga aaaaaagaat tgccgtaaaa
    37741 gagctggcag aaatcacttt ctccagcaca agtaccttac gtcgtgattt aattttctta
    37801 gaaaatcaag gtcttatcaa aagaaagcac ggatacgtga ccctgtcctc tatgaacaca
    37861 attgaacttt ctcatcaaat acgtgaagga gaaagtacta ggcaaaaaag actaatcgct
    37921 agtctcgcta aagactttat tcggtctggt atgtgtatct atctggattc cagtactact
    37981 gtctacgaac tctgtcccta tctttctgaa cttgataatt tgattatttt tacaaatggt
    38041 ttacatactg cacaaaccct atctgaaact gttaaagata gctccaaaat ctttatcaca
    38101 tctggcgagg tcaaacatca atcctgttcc gtggtcaact atgataagga aaattcttta
    38161 ttagatcatt ttaatatcga tttagcattt tgttcagcaa gaggtattga tgaccaatat
    38221 gtttatgaag cttctctcag ccaagctatt tcaaaaaaga atattattga caaagcccat
    38281 gaaaccatct tactgattga tagttctaaa ttttacaaga ctggattttt taaaattaat
    38341 cccctctcca aatacacaac ctttatttca gacaccgtgc cagatcaaaa attattagac
    38401 gcagtcgaat tatttgatgg agaatgggtt tctgatattc aatgaaaatc aaataggaag
    38461 ctagtctcag cttgctcaaa gtacagattt gaaaactgat gaagtcagct cgaaacactg
    38521 ttttgaggtt gtagatagaa ctgatgaagt cagtcacata tatacggaaa gacgaagctg
    38581 acatgatgtg aagagatttt cgaagagtat tcgttctgtc tgctgactga tttacaaata
    38641 ttcaccacat gacattattt tcttagcaac cccaaaaaca gaggctggac aaaaactcaa
    38701 tttcaggaga aaatggagta aaccttccca caataaaacg catagtatca agtttttgca
    38761 cacctgatat tatgcgtttt tctgatttta aagactttgt cgcctagacc ctatatttca
    38821 agaattaagt gaccttgatg atctaaattt attgtggtat actatttttg tcatcggtta
    38881 ccgattacgt tcctatgggt tcgtgagagg aggtgaaact aatgagcctt atcatagagc
    38941 tcgctcttac tattatagcg gatgttatag ctggaattat cttgtatttc gtctgcagat
    39001 ggctagatag taaggagtag accgactgac tagcctataa acacccgtta aatcgctaag
    39061 atacgtcaaa aaagccctta actacggcca tagttagggg ctttggtgtt ctaatgaacc
    39121 ttatcaatta actacatttt agcatataat ctacaatagt tcaagcatta agtgaggttg
    39181 atgatctaaa tttagtgtgg tatactattt ttgtcatcgg ttaccgatta cgttcctatg
    39241 ggttcgtgag aggaggtgaa actaatgagc cttataccag agcttgctct tactattata
    39301 gcagatgtta tagctggaat tatcttgtat ttcgtctgca aatggctaga tggtaagaag
    39361 tagaccgact gactagccta taaacaccca ttaaatcgct aagatacgtc aaaaaagccc
    39421 ttaactatgg cactagttag gggctttggt gttctaatga accttataca ctaactacat
    39481 tctagcatat aagcccagat atttcaagag ttttatttat tttttcaggt tcccttagtt
    39541 ctgaaaggtc tataatgaag ttagccatct agtatcaaaa aaccgactag ctcttatgaa
    39601 ctagtcgatt tctcatcaat gcgccaacat ttcttgggcg atttcttggc cagataggtt
    39661 atctgggtag taggttggcc agttgtccat ttcttcaaag agggcttctt ggcttgtgcc
    39721 tccaaagaag atatggaaat gttctgcctt aactggggca acattgtggt cactaaactg
    39781 aacatacttg aattgtccag cgtcagcatc tgtggcttca aagaggaaac gcacgccacg
    39841 attgcctttc ttgtaagtca aaattttctt accgacatac ttgtaagtgt atttcttgct
    39901 ttgtccacct tgaacaaatt ccatagtatt atcagtaatg ttaatcttag tcacatctgt
    39961 ctgatagcct tttgtatagt aagccttgta ctcagcctgg gtcatcttac cagttaactt
    40021 agccttgtag tcaaagactt ggtcaaacgt gccgtcttca aggaaaggat aaactgattg
    40081 ccagttacct gcatagtcac tcaaggtacg gtccttgaca gctgcatcct cgaagtaacc
    40141 attttggact gtcttggtat cctctgcctt ttcaggttcg attgctgggc cttcttggtc
    40201 tgttgtttgt ttcaaagcct tgaggttttt ctccatcacg gaaatgtagt tttctccagc
    40261 cttggtgtcc tcttctgtca gactttctaa aggattgagg acatcagttt tgacacctgc
    40321 ttcttttgaa agtgtgttag caagggcttg tgaggcattt tcttcaaaat agatataggc
    40381 gattttattt ttcttgacat actctgtcaa ttctgccaag cgagcagctg atggctctgc
    40441 atctggagaa agtcctgaga ttgcgacttg tttgagtcca tagtccaagg caagatagtt
    40501 aaaggctgcg tgttgagtca caaagctctt ttgttttgct tgagacaagc cttctgcgta
    40561 agccttatcc aaggcttgca atttttcgat ataggcagct gcattcttct caaaggtctc
    40621 ttttttatca ggataatctg ctgacaagct gtcgcggatg tgctctacta gtttaatggc
    40681 acgaactggt gataaccaaa catgggggtc aaactcatgg tgatgacctt cttctccatg
    40741 gtcatgatct ccctcttctt cctcgccacc tggcaagagc aacatatcgc ctgtcgcctt
    40801 gatggttttc acttttttct tatccaaggt atctagcaat ttaggtaccc atgtttccat
    40861 gttttcattt tcataaacaa aggtatctgc atcttggatt ttggcaactg ccttggcaga
    40921 tggttcgtat tcatgaggtt ctgtcccagc accgattagg agttctacat tagccgtatc
    40981 tcctgcgact tgcttggtaa attcatagac agggtaaaag gttgtcacga tattgagttt
    41041 accatctgcc tgtttttgat tggaacaagc cactaaaaac aaggcacata gactggctag
    41101 taataagcta atttttttca cgttcgtctc ctatttgata aaacgtctta ctaaactgat
    41161 tagtataaag acagttacaa aaataatggt aatacttgca cttgcaggtg tttctgcata
    41221 gtaggaaatg taaagtcctg ctaccattcc caaaaagcca atcgcactgg caagcagcat
    41281 aaccgattta aagtttttcc ccagacgcag ggcaatacta gctggcaaga ccataatggt
    41341 cgataccaga agagctcctg ctgcaggaat cataagggca atagccaccc ctgtcaccat
    41401 gttaaaaaga atggacatgg tacgaactgg caagccatcc acaaaggccg tatcttcgtc
    41461 aaaagttaag atatacatag gacgaagaaa gagaaaggtc aaaatcaaaa caaccgccgc
    41521 aatgacaaag agggaaatga cctgttcttc actgatagtc acgatcgaac caaagagata
    41581 ttggtccaaa ctcattgaac tcgagctttt acccttgctc atgacaatca gagaaacagc
    41641 cagacctgtt gacatgagga tagctgtccc gatttccata aagctcttgt aaaccgtacg
    41701 gagatactcc agaaagaccg ccgcaatcaa gacaatggca atagtagaaa cagttggaga
    41761 aatccccaaa accagaccaa aggctacacc tgaaagtgag acgtggctaa gggtatcact
    41821 catcaaactc tgacgacgca agatgaggaa ggttcccaat accggtgaga aaagactcat
    41881 agcaataacc gccaaaaagg cgcgttgtat aaagtcgtaa gataataaac taagcatggc
    41941 ccacctcctg gccattctca tgaacgttga aacaacgcca tggcgagtct tggttacgga
    42001 ctagatgaat attgcgatcc gcataatcct taacttcttc agggtcatgg gtaatcatca
    42061 aaacagcctt gccatgatga tgggcgctgt ggtgcatgag ttcgtaaaat tcatttttac
    42121 ttcctgcatc catccccgtt gtcggctcgt ctaggataaa cacatcaggg tcagaagcaa
    42181 acatacgcgc aattaccgct cgctgctttt gtcccccaga tagagacccc aagcgtttgt
    42241 ctcgatgttc ccacatgcca actgagtcca gactggcctt gatatgctcc tcatcatgag
    42301 cattcaaacg acggaaccag ccttttctcg gatagcgacc cgacttgaca aattcataga
    42361 ccgtacttgg aaaaccagca ttaaaactgg caatttgttg aggaagatag gctattctca
    42421 atttcttacc ttgcgtattt gtctttgaaa tagccacctt tccaatgcgt ggttgcagaa
    42481 ttccaagact agccttgatg agcgtcgtct tagccgctcc attttcccca gtcaaggtaa
    42541 caaattcccc actatcaaca caataattga tatgttcaag aacaggctcc ttatcataat
    42601 agaaggacaa atcctctacc gtaatatatc tcattatttg atttctccta ctaaagcagt
    42661 caaaaaccgc tgaatcactt tttgttcatt tggagtaaac tgagtcgcca cttgttcata
    42721 ggttaaaagt gtatgctcat ggtgatggtg gtgctcctca gcgattggac gagccaagtc
    42781 agtcaactga taaaaaatca cacgcgcatc tttagaatct ttagatgttt ccaacatccc
    42841 ttccttgacc aaagacttaa tggccttggt aactgccgcc tgactgacat tgagacgacg
    42901 ggccaattct gaatttgtta aagattcctc tgacaagagc ataaggatat gctcctgagt
    42961 attggtcagg gccacctcgc tagtgcaatg acctattagg atttcatgct gattttccgc
    43021 ctgcaaaatc acctcattca aaaaagcatt gatatccttt gctagctgtc tcatatctga
    43081 ctcctttcct tttagacttc tcttttttaa gagaaaaata ctattctttg acattttgtt
    43141 taccagttaa ttatatcaca agcaaaaaaa gagtcaagaa aaaacgtgaa aactagtttc
    43201 attcttgaac tcttctatat tatattatct attgaaattc tttgacatct ccatcataag
    43261 tcgcccaatc tttgctgaaa aagcgctcat tcagatggta agtcggagct ggtgtgggat
    43321 tggataggaa aggatcaact gccttgtcaa aagccaacca acccaaccaa ccaaggtgaa
    43381 tggtgtcctt cataaagaaa ggctccccgc cgtccttaga aaaatctgct atattggtaa
    43441 aaccttgact ttctaactgg tagcgaatct tctgcaccgt ttgttggtac atatcctctc
    43501 gtagaccagc atagtccatc cattttttat taacaggtgg aatgataaaa atcgggttta
    43561 ccttagattt agaaaactgt gttaaaacca actgcaagtc attatactct ggcgacttga
    43621 gataggtaaa gcttttctga gaatccttta atttcttcaa atccttcttg atctgctcat
    43681 tatagaaata attttccatt cccatctcat tattggaagt atttttttca gcatctgctt
    43741 tgacaacatc ttctattgct tgataagaaa actggtctgg caagattttt aaatacttag
    43801 ctacatgctt atcgtagtta acatagcctc taaccgaaaa ctgaccaaaa aaggaggctt
    43861 ggcgttcatt aaaacgagcc aataattcaa tcatttcatt gtctgctgtc gacaattctc
    43921 ctttacttgc caacttctga accaggtcct tcatagctac gtttgggaac tgttgcagta
    43981 agcgagtcgc tgcatattga ctagcctgat ccccagattg atgtttcaga aaactagtca
    44041 actggtctcc attaaaatac tgctggaagg ctgctggatc atagccattt ttactgaacc
    44101 actgaggtga gataacatac acaacttgtt tattctccag ctgtggtaac atctgttgca
    44161 ttccaaaata ttggttaagc gatgcagctc ccccctgtcc taaaagataa ggacggtagg
    44221 aacgattgta tttctcagct aataccgcag gatgagcacc gtcaaaacga agccattcac
    44281 tagagccaaa gaagggaaca aaacgcacat ttggatcaga tagtgctctg actttttgac
    44341 ttcgctcctt aaaactatcg atagtagtag ccactgctga acgcttttca gctcctagat
    44401 tatgatgcat ctcagtagga taaaagaaaa tgagcagaaa aaccaacaaa ccagcgatca
    44461 agaccggtcc gaagatcatc cataagcgtt taagcatttt gtagctccac aataccagct
    44521 atgattttat tagctgtatt ccagtcgtca cgaccaaact ctgttacagg gacacgaatg
    44581 tcaaaacggt tctcaatctc cacaatcaac tcaaccgttc ccatactatc caagacacct
    44641 gcatcaaaaa gatcttcatc catcatgtca gaaacatctt ccataaacaa ctcatcaata
    44701 atttcaataa cttctgattt gatatccata ttttatttcc ttttattttt taaaccatag
    44761 attattcaag aatccagaaa agattaagaa tgacaacatg acaacatgga aagtgacaac
    44821 catgccaagc aactgaatcc agcgattctc aggtagggca gccttccctg cttttttccg
    44881 ttccttattg agcgtttttt tcttgcgaac ccaggcatca ttgatgacca agcctagtcc
    44941 atgaaagagt ccataggcga tatagtacca ggtcacacca tgccaaaatc ccataatcag
    45001 catatttaca atgtaagcca tgcttgaggt tacattacga tttttaaaga ctttctttct
    45061 ggttaacacc atcaccattc gcataaagac aaagtcacgg aaccagaagg acagactcat
    45121 atgccagcga ttccaaaact cctttaaatc ccttgataaa aagggcttgt taaagttgat
    45181 agggctacgg attcccatca agtttgagat ggccaaagca aacatagaat aacctgcaaa
    45241 gtcaaagaag agctccagac caaaagtata cataactgcc aaggcataga gattaaagaa
    45301 gccacctgac tgcaaggcta aattcttcag aggaggtagt aaggtctctc ctaaaacatg
    45361 agctaggata aacttataca aaaagcccca catgatatag cggacagatt catccagcat
    45421 atccatcaac tcatctcgct caggaatggt ctgataattt tcattaaatc gcttaaagcg
    45481 atcgattgga ccactcgaga aagttggcat gaagagaagg aaacggagga attcccagag
    45541 ggtaaaatcc ttaatcactc catctctcag ctcgatgata atcccaaccg aacgaaaggt
    45601 caggtaagaa attcccaaga acccaagcaa agactgcgtt ccattgatag ctggttgcac
    45661 cttgacaaag ataatcggaa gtagggacag aaaactaact aagtagaaga cccacttgcc
    45721 atccttgctt tttcgataat gcttgtagaa aagcaggagc aatatttccc agcaaaggta
    45781 aatacccaag gcagctagtt gattggtctt tccacccacc aacatggtga caataaagaa
    45841 gagacttacc aacacttcat accaggcaaa gcgtttcttg aaaaagaggc ctataaagat
    45901 gggcaaggtt gcagcaatca cataaacaaa atactgagga ttgccatatg gctctaaatg
    45961 aggaagctgt tgaaaaaact ccatcatctc ttattcacct cgttaatcaa tcctttgatg
    46021 tcaatctttc catttggagt tagtggcaaa ctgtctcggt aaaggaattt agatggcatc
    46081 atgtaggaca tcatgatgtc tgtcaggtct tccttgatgg ccttggtaat atcgatatct
    46141 cgctcaaact gctcacgaac accgtctttt aagatgacat aagccaatag attttgtacc
    46201 ttatggtcct tgttatagcg cggtactgcg acagcagatt cgataaagcg agacttgttg
    46261 aggttttgag agacatcttc taactcaatg cggtaaccgt taaacttaat ctggaagtcc
    46321 atgcgtccgc cgtaaagaag caagccctca tctgtcatgg ttcccacatc gcctgtgtga
    46381 taggctggca gaccttcaaa ctcaaagaag gcttctgctg ttttttcagg attgttcata
    46441 taaccttttg aaacagctgg cccagaaaca atgatttctc cctgttcgcc atttggcagt
    46501 ttatttcctt cctcgtcaat gataaaggtt ggagaatcag ccttggtata gccgattggt
    46561 aggcgtttga gagtcgctaa catctcgtct gtcacggcaa ctgctgacag agctactgtc
    46621 gcttctgttg ggccgtaagc attgatgata cgggcatttg ggaaacgctc gcgcagtttt
    46681 tgagctgttt tgaccgtcaa ttcttcacca tcaaagtaga aatgcgtgat tccaggcatt
    46741 ttctcactgt tgaagtattc agacaacatg gccatatctg caaaggatgg tgttgatgtc
    46801 cagatagcga ttggcaatga aaagatagcc gcaaagagtt gcttaaagtc ctgagtgatg
    46861 actgaaggaa gagtgaaaag cgtaccacca agtgccaagg tcggtgccca atacatgaca
    46921 gacaagtcaa aagaataagg tggctgtgcc agcatttgcg gacgactcgg tgtcgcaaat
    46981 tccttatccg taatcatcca gtttgtaaag ctgaggagat tatcatgtga aatctgcact
    47041 cccttaggct taccagtcgt accagaagta aagataatgt agtaattatc atctcccttg
    47101 actggatgcg tgatttcata gttgttccct tgggcaaagg cttcttgaac ctgagctaga
    47161 tttatcattg gtgtagaaac ctgctccaag ggaaaggctg aaatggcaat aatcaagctt
    47221 ggctctgcta cttctaaaat agctgaaact cgctccaagg ccgaatggct atcaattgga
    47281 atgtaggcat gacctgactt agtcagcgct acaaaggttg ccaacatttc atattcttgg
    47341 ccaccaaaaa caaccacagg agacttctca ggcaagccta gttggtcaat gactgcagcc
    47401 aaactatccg aatcagcctt taaatcgcca taagtgtgtt cctgccccaa aacattatag
    47461 acaggatagc taggctgtgt ctgagcaaaa tgctcaatgg tttcaatcat atctgctatt
    47521 ggtttatttg acacaatagg gattctcctt caagttaaaa ttcattatag ataaagcttc
    47581 cttgaccctg accaagatag ctaaagaagt aaagcagccc tagaaagata agaaaataca
    47641 aggctgtccg accaagaaag aggtacaatt cttttctctg tttcatcaag aaaaaccatt
    47701 catttctgta atttttcgct aaaataagag tgattcttac tagcttattt ttctaccatt
    47761 gtaccacttt atatagtatc ttttcaattg tttaccgtat gtttccaata gatttcagct
    47821 tattttaagg attatacagt ttttctatgt atattttcaa atagagtgat cctgcttcaa
    47881 aactccattt caggagacaa tgaagtaaat cttcccataa taaaacacac aatatcaagt
    47941 tttttcaaca cctgatacta tgcgcttttc tgatttttaa agacttttta accactctct
    48001 catttaaaat aatctcgtct gatataaatt aaaatagctt ctatcatcag acaaatggct
    48061 gatagccaaa aactgatgct aataccaaaa ctctcagtaa tatagctcat tagcaaaaca
    48121 aatactgaaa atgctaatgt agaaatcact tcaagaacgg aatagacatt aactaaatga
    48181 ttttcctcta ctgtttcctg aagaaataca ctttcaggaa cttcttttag ttgcgataac
    48241 ataccaacta aagctgaaaa taataaaaac atctgtgcgt ttggaaaata tagaatagtc
    48301 agtgtcacta ttgccatagc tacaagagga aaaagaatac tttcccattt agcagcaagg
    48361 aacttttcag atagcctaaa agcaattaag ccactaatta taataccaat agagtatgct
    48421 gtattagaat atccccagta actttccgtt ttatttaata actccgttac aaaaacaagt
    48481 ataatggaag aaacccaaat cgtatttgaa aaaatttcca ataaatttgc tgatacaaaa
    48541 agtcttaatc taggatttct agcaactaac ttccaacctt tgagcaaaat ttcaagatta
    48601 gtttctgact ctaacacctc cacttcagcg ttaggaagaa ataacatcag aaagctagaa
    48661 atgatataca agactaaatt gatacacgtg gtaggtaaca gaccaattgt tgcaaacaag
    48721 agtccaccta atccccaacc tatcaattga acagcttcac cagtcattga taaggctgaa
    48781 ttagccttac ccaaatcggt cgcatagcgt ggcacaatag cataggaaac gggtgctgca
    48841 aaaccatcta gtatggaaat tgcaacaaca aatagatagg tcaccaaagg cgctacggat
    48901 tgcattacgg taaacattcc taccagtatc gccaataata tagtctttcc aaattgagat
    48961 aaagataaaa ccctatttag cgctaacctt ttagtaacca acggaactaa aagactcgca
    49021 acaaaagagg atattcctat taagatagga actagtgatg tggcaattac tgattttgaa
    49081 ataatgtata tgttagcaat gattgttact ctaaagaaaa tatctgctaa atttgcaaat
    49141 aattgagaga ctaacaactt gacaaatgaa ttagacatgt agcgctcccc ctttagttac
    49201 aaactttgga attaaatttg atttttaata ttttagcata aaatagcaga aaacaaaagt
    49261 gaggtttttt acatgaaaaa acaaaaacta ttgcctttat tattcctaat tttaggagga
    49321 attatgatta tcgttgttgg ctagtactaa gaagttagtt agtagaataa ttacatcttc
    49381 aatcgaaaaa gagactggaa aaagtcttaa aaatcagaaa aacgctcaaa tcctttggcg
    49441 ctctaagctt ttctaatgat agatttagat agtcaaaaaa atatctgaaa agttcccagg
    49501 atcgtcgtct cagcatcaaa aatacgtgaa atttgcataa ttaaaataaa tttcagggga
    49561 gttaatcgag taggggataa tctctagccc ctctcacacc accgtacgtg ccgttcggca
    49621 tacagcggtt caactaactt ttaacgcatg tcgttcaagg taataatcca aacacgaaac
    49681 cagtccacgt ttttccagga ctggttttga tatagcacgt ttaagtaccg acttctgagc
    49741 tactaattga taatggtcgc cccagccaga taccttatct gctatccatt taggaactcc
    49801 taacttaagc aatccccata atcgtctcga tttcttcttc cattgcttcc agataatcac
    49861 tcgtaggcga gtacgcaagc gctcatctat gctggcgact atacttttca tatttcccaa
    49921 tgagaaatag tttatccatc ctcgaataga caaattcagt tgctcaatac gtcttgttag
    49981 gtctatactc catttcctct gtgttagttt cttcaattta agcttaaatc tccgaacact
    50041 atcttgatgt ggacgacttt tccaaccatc tgatgatttc cagaacccaa aacctagata
    50101 tttcaactct cttggtctgg taatcttagt cttggtcatg tttactttca aacctagccg
    50161 tttctcaata aaacgactga ctgaatacat cacacgctta gcggctgcct cgcttccgac
    50221 cgtatcacac aatcatctgc gtagcgcaca aatcgaagtc ccctcttttc taattccttg
    50281 tccaattcat taagcatgat attggataag agaggagata aatttcctcc ctgtggtgta
    50341 ccaactagtg ttttataacg ttgaccatta atgataacac ctgaatgaag atacttacga
    50401 atcaaggatt ccgtatctcc gtcttcgata atgttatgta ctaaggacat caatctatct
    50461 tgaggaactg tatcgaaaaa tttctctagg tctatatcca ctatccactc atagccgtca
    50521 tttaagtatt ctaagagctt catgatggct ttttcacatg acctatttgg tctgaaacca
    50581 taactcgtat ctgagaaatg gggttcacaa atggggctca tgacttggac aatggcctgt
    50641 tgaatcattc tatccataac tgttgaaatt cctagttgac ggatgcctcc gtctggttta
    50701 ggtatctcaa ctttaagaac tggttgaggc ttatattttc tctgttttat cagttcctta
    50761 gtcaagcgcc agttttgtct gagataatta tccatctctt cgatagtcat tccatcaatc
    50821 ccagctgagc ctttattgga ttttacttga ttgtaggctt ccagcatatt ttcgcgtgat
    50881 aatatcttat ctagcagttt tgacatgtgc gtattccttt cttgttttgg tgcctgaggg
    50941 acatcttata ttggtgaacc ttcatctagt cattacgtgt caaagtccag ttctatcaga
    51001 ccactcattt tacagacaca agtgaagtag gattacttcg atctgtcgtt ttctctttct
    51061 agcgacagac ctcaaacagt ctctccccag actgtttgag tattcacccc ttcgctccac
    51121 ttccactaca gaagtttcct cactactatg ggctcggctg acttctcatg attcgttgtt
    51181 actacgcttt cagcgctcat gaaacctcac gggataagtc gtacatcttt cctcgtttat
    51241 acaagatatg aggacgttaa aaggttacag tgaaaatagg aaatctgacg cagagtcttt
    51301 agactctaga aagatttatc tttttcacac aaaccttagt ccgaattcaa ttactctcgt
    51361 gatttacaca tataggttac gactaccttt ttggacttta gagtttgaag cctccttatc
    51421 cgctatatac gccttactat cacgttcctg ttcgtagagc cacgatttcg ctatcccttc
    51481 ctctgacgat tcttatttcc tgcgtcagac ttaaaacggt ctatccccag accgttttaa
    51541 tccgctacct cacgatagtc aggcttggga atcgctattg ggttcaccg
//
LOCUS       DAVLHM010000008        51101 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLHM010000008 DAVLHM010000000
VERSION     DAVLHM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.008"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(44..928)
                     /locus_tag="VXE45_000497"
     CDS             complement(44..928)
                     /locus_tag="VXE45_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0788588.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(932..1318)
                     /locus_tag="VXE45_000498"
     CDS             complement(932..1318)
                     /locus_tag="VXE45_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0788589.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(1311..2654)
                     /locus_tag="VXE45_000499"
     CDS             complement(1311..2654)
                     /locus_tag="VXE45_000499"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0788590.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(2741..3625)
                     /locus_tag="VXE45_000500"
     CDS             complement(2741..3625)
                     /locus_tag="VXE45_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788591.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(3637..4254)
                     /gene="cysE"
                     /locus_tag="VXE45_000501"
     CDS             complement(3637..4254)
                     /gene="cysE"
                     /locus_tag="VXE45_000501"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0788592.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(4270..6483)
                     /gene="pnp"
                     /locus_tag="VXE45_000502"
     CDS             complement(4270..6483)
                     /gene="pnp"
                     /locus_tag="VXE45_000502"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0788593.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(7168..8034)
                     /gene="metF"
                     /locus_tag="VXE45_000503"
     CDS             complement(7168..8034)
                     /gene="metF"
                     /locus_tag="VXE45_000503"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0788594.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELVPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(8098..10347)
                     /gene="metE"
                     /locus_tag="VXE45_000504"
     CDS             complement(8098..10347)
                     /gene="metE"
                     /locus_tag="VXE45_000504"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0788595.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLSAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFTTERVGENAELRARIAG
                     LTDADYTRLPVFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(10608..10874)
                     /locus_tag="VXE45_000505"
     CDS             complement(10608..10874)
                     /locus_tag="VXE45_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0788596.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(10958..11447)
                     /locus_tag="VXE45_000506"
                     /pseudo
     CDS             complement(10958..11447)
                     /locus_tag="VXE45_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11603..12604
                     /locus_tag="VXE45_000507"
     CDS             11603..12604
                     /locus_tag="VXE45_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0788597.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTDSGIAPVTVIVKKSYDFYTKAETFHTTRFGTIVLHSRKQDIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(12672..15077)
                     /locus_tag="VXE45_000508"
     CDS             complement(12672..15077)
                     /locus_tag="VXE45_000508"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0788598.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(15154..15663)
                     /locus_tag="VXE45_000509"
     CDS             complement(15154..15663)
                     /locus_tag="VXE45_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788599.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(15663..16709)
                     /gene="pheS"
                     /locus_tag="VXE45_000510"
     CDS             complement(15663..16709)
                     /gene="pheS"
                     /locus_tag="VXE45_000510"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0788600.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(17258..17620)
                     /locus_tag="VXE45_000511"
     CDS             complement(17258..17620)
                     /locus_tag="VXE45_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0788601.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFGNE"
     gene            17628..17708
                     /locus_tag="VXE45_000512"
                     /pseudo
     CDS             17628..17708
                     /locus_tag="VXE45_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(18115..18273)
                     /locus_tag="VXE45_000513"
                     /pseudo
     CDS             complement(18115..18273)
                     /locus_tag="VXE45_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(18546..19235)
                     /gene="rplA"
                     /locus_tag="VXE45_000514"
     CDS             complement(18546..19235)
                     /gene="rplA"
                     /locus_tag="VXE45_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0788602.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(19443..19868)
                     /gene="rplK"
                     /locus_tag="VXE45_000515"
     CDS             complement(19443..19868)
                     /gene="rplK"
                     /locus_tag="VXE45_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0788603.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            20000..20137
                     /locus_tag="VXE45_000516"
     CDS             20000..20137
                     /locus_tag="VXE45_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788604.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(20177..20893)
                     /locus_tag="VXE45_000517"
     CDS             complement(20177..20893)
                     /locus_tag="VXE45_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0788605.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(20896..21366)
                     /locus_tag="VXE45_000518"
     CDS             complement(20896..21366)
                     /locus_tag="VXE45_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0788606.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(21368..22405)
                     /locus_tag="VXE45_000519"
     CDS             complement(21368..22405)
                     /locus_tag="VXE45_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0788607.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(22609..23934)
                     /gene="brnQ"
                     /locus_tag="VXE45_000520"
     CDS             complement(22609..23934)
                     /gene="brnQ"
                     /locus_tag="VXE45_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0788608.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(24105..24197)
                     /locus_tag="VXE45_000521"
     CDS             complement(24105..24197)
                     /locus_tag="VXE45_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0788609.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(24240..24392)
                     /locus_tag="VXE45_000522"
     CDS             complement(24240..24392)
                     /locus_tag="VXE45_000522"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0788610.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LTDSYD"
     gene            complement(24552..25130)
                     /locus_tag="VXE45_000523"
     CDS             complement(24552..25130)
                     /locus_tag="VXE45_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0788611.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(25184..26584)
                     /gene="pepV"
                     /locus_tag="VXE45_000524"
     CDS             complement(25184..26584)
                     /gene="pepV"
                     /locus_tag="VXE45_000524"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0788612.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(26597..27202)
                     /locus_tag="VXE45_000525"
     CDS             complement(26597..27202)
                     /locus_tag="VXE45_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0788613.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            27373..28173
                     /locus_tag="VXE45_000526"
     CDS             27373..28173
                     /locus_tag="VXE45_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0788614.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(28351..29184)
                     /locus_tag="VXE45_000527"
     CDS             complement(28351..29184)
                     /locus_tag="VXE45_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0788615.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(29174..31018)
                     /gene="uvrC"
                     /locus_tag="VXE45_000528"
     CDS             complement(29174..31018)
                     /gene="uvrC"
                     /locus_tag="VXE45_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0788616.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(31057..31758)
                     /locus_tag="VXE45_000529"
     CDS             complement(31057..31758)
                     /locus_tag="VXE45_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0788617.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(31837..33069)
                     /gene="murN"
                     /locus_tag="VXE45_000530"
     CDS             complement(31837..33069)
                     /gene="murN"
                     /locus_tag="VXE45_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0788618.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(33074..34294)
                     /gene="murM"
                     /locus_tag="VXE45_000531"
     CDS             complement(33074..34294)
                     /gene="murM"
                     /locus_tag="VXE45_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0788619.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(34406..35185)
                     /locus_tag="VXE45_000532"
     CDS             complement(34406..35185)
                     /locus_tag="VXE45_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0788620.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(35254..36915)
                     /locus_tag="VXE45_000533"
     CDS             complement(35254..36915)
                     /locus_tag="VXE45_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0788621.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(37090..39312)
                     /gene="recJ"
                     /locus_tag="VXE45_000534"
     CDS             complement(37090..39312)
                     /gene="recJ"
                     /locus_tag="VXE45_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0788622.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            39589..40347
                     /locus_tag="VXE45_000535"
     CDS             39589..40347
                     /locus_tag="VXE45_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0788623.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            40387..41151
                     /locus_tag="VXE45_000536"
     CDS             40387..41151
                     /locus_tag="VXE45_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0788624.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            41164..41841
                     /locus_tag="VXE45_000537"
     CDS             41164..41841
                     /locus_tag="VXE45_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0788625.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            41851..42510
                     /locus_tag="VXE45_000538"
     CDS             41851..42510
                     /locus_tag="VXE45_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0788626.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            42768..43958
                     /locus_tag="VXE45_000539"
     CDS             42768..43958
                     /locus_tag="VXE45_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0788627.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(44279..45160)
                     /locus_tag="VXE45_000540"
     CDS             complement(44279..45160)
                     /locus_tag="VXE45_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0788628.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(45299..46627)
                     /gene="vncS"
                     /locus_tag="VXE45_000541"
     CDS             complement(45299..46627)
                     /gene="vncS"
                     /locus_tag="VXE45_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0788629.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(46624..47280)
                     /gene="vncR"
                     /locus_tag="VXE45_000542"
     CDS             complement(46624..47280)
                     /gene="vncR"
                     /locus_tag="VXE45_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0788630.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(47329..47412)
                     /gene="pep27"
                     /locus_tag="VXE45_000543"
     CDS             complement(47329..47412)
                     /gene="pep27"
                     /locus_tag="VXE45_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0788631.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(47592..48971)
                     /gene="vex3"
                     /locus_tag="VXE45_000544"
     CDS             complement(47592..48971)
                     /gene="vex3"
                     /locus_tag="VXE45_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0788632.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(49023..49670)
                     /gene="vex2"
                     /locus_tag="VXE45_000545"
     CDS             complement(49023..49670)
                     /gene="vex2"
                     /locus_tag="VXE45_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0788633.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(49683..50960)
                     /locus_tag="VXE45_000546"
     CDS             complement(49683..50960)
                     /locus_tag="VXE45_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788634.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT        14439 a        11625 c         9703 g        15334 t
ORIGIN      
        1 aaatggagaa gatggcaatc ctcttctcca aatattaact tctttacaaa ccaactatag
       61 ttgacaaaga acctaaaatc aattgataac acaaggtcag gtcggtcaac tctttcaact
      121 gaagccctgt caactcttcc catttatcaa tcttgtattg gagagaattg cggtgcagat
      181 agagttgctg ggctgtttta gtgagaacag cactattttc ccaaagagag agaatgattt
      241 cctgaatctg atcttgatcc aaaatcatct ggtgtagaca ttctttaatt ggcttcaagt
      301 ccacgagtct ttctcccata ctccaaagat agagctgaga aaaagtatga acaccttggt
      361 gaccctgacg ccaccatgtc ttgaacaaat cccgctcagc tttgattaag tctgataggg
      421 cttgatgtcc tgtctgagac caaacctgac ccaacatgat agaaagacga agtccaaagt
      481 catactcaac cgcttcaatc gtatcactta aaatatctct tacagaagtg tatttgtctt
      541 gttgaagcac gaaaacataa tcctgagctc cgacctgtag cactgtctga caattcggaa
      601 aaagagtccg catcatatct agccaagaag ccagattttc ctgctgaaaa taagaaagat
      661 ggcaataaac caactgaatc tttttaaaaa cttgcggtgc ctgtcccttg ccttcaacca
      721 gataggaata ccaagggttt agcgaacgag cctgctcctg ctgggtcaaa agggcaacca
      781 actgcttttc acgctcgctg agcccagctt cctccagcaa aatccactgc tgagaagcta
      841 aagggagcgt gagatagccc tctttctcta ctggttggtc tgaaatccga gcctcaggaa
      901 accagtcttg tagttctttt tccctcatgt tctagccctc cactttttgg atgcaccatg
      961 aaaccaaact ctcaagacgt tccagattct cagtcatatg gagatagccc ataaccgctt
     1021 caaatcccgt ggacatacga taagtcacga catctgcatt tttagccttt gtgtggctat
     1081 tggtattgcg gccacgtttg tagatttctt cttctttttc cgttaggacc tgctcctcca
     1141 acatgagagc aatcaggcga gcctgagcct tggctgacac atacttggtt gcttcttgat
     1201 ggagtttatt gggtttggtc atacctttga ggatgaggtg acggcgaata tacatagaat
     1261 acaccgcatc cccctcaaag gctagcgcaa tcccgttaat gagattgaca tcaatcacgt
     1321 gtccacctca ctccatcctt ggtatcaagg agcttaattc cttgagtaac caattggtca
     1381 cggatttggt ctgctgtctc aaagtctcga ttggcacgcg cctcttggcg tttttgaatc
     1441 aagtcttcaa tctctgcatc caaaacttcc tcaacaaaga caattccaaa aatttctaac
     1501 atatctgcaa gagcttgctt gacacttgca tcatagttcc ctgagttgat ccatttggcc
     1561 atttcaaaga caactgtgat accgttggca gcattaaaat cttcatccat agctgctaca
     1621 aacttatctt taaagttttg taactcttgg gcatccacgt ttcctgtaaa tggttgttcg
     1681 taagtattct tcagatactt gagattggtc tcggcatcgc gaactgcctt ttccgtgaag
     1741 ttgataggct tacggtagtg ctgggtcgca aagaagaaac gaagtacttg cccatcaaga
     1801 gttttaaggg catcgtgtac cgtaatgaag ttacccaagg acttagacat tttgacattg
     1861 tcgatattga caaagccatt gtgcatccag tagttagcaa aagccttgcc tgttttagct
     1921 tcagattggg caatttcatt ggtgtggtgt ggaaactcta ggtcagctcc accaccgtgg
     1981 atatcaatgg tatcacctaa aatctctgtc gacatgactg aacactcaat atgccaaccc
     2041 ggacgtccag gtccccaagg actatcccaa gaaatctcac ctggtttgga agatttccat
     2101 agagcaaaat ctacaggatt ttccttacga gccgtttctt catcggtacg acctgaagca
     2161 cctagctcca aatcttccaa ggttttatta gccaatttag catagttgtg ggatttttct
     2221 acacggaaat agacatcccc ttgactctca taggcaaagc ctttctcgat caagtcttcc
     2281 acaaaacgga tgatgtctgc cataaactcc actacacgcg gatggcgagt cgcaggtttc
     2341 acgcctaagg ccgtcacatc ctcacgaaag gcagcgatgt acttatccgc aacctcctga
     2401 ggtgtgatgc cttcttccct ggcacggttg ataatcttat catccacatc tgtaaaattg
     2461 gaaatatagg caaccttata cccacggtac tcaaaatagc gacgaatcgt atcaaaagct
     2521 accgtcgaac gggcgtttcc cacgtgaata tagttgtaca cggttggccc acaaacatac
     2581 atcttgatct tgccgtcctc aatcgggaca aattctcgca aatcacgaga catggtgtca
     2641 tagattttaa tcataaatca taatcaggaa agctaaaatc caagaactgt tagtttcatc
     2701 actaaactaa gagctcaagt aaatttcagt ccgaatgtct ctacacttcg gaatcccttg
     2761 ctcctttctc attcagataa accacctgtg tctgtttgac aaagccaatt ttttcataca
     2821 aacgtttggc acctacattg ctatcttcca ctgcaatctg aaattccttg tcattttgct
     2881 caattagttg gttgacgagg gattttgcta agtagcttcc atagcctttc ccacgttcag
     2941 gttccgatat tgctaaaccg tagaagtaat tcgtattagt cgataaatct accgtgcaag
     3001 tcccaataac ctgaccgtct tttaacaaaa tatataagcg actttctgga tccttcagag
     3061 cttcagcgac atatctatcc acaacttctc tcgattcatg ttcctctgaa aatgcctgaa
     3121 attttaattg actaatttga tcctgatacg aactatctgc taacaaaact tcaagatggg
     3181 aaacatttgc taacggataa ggtcttctat ccttacctaa ccaagtttct gtctcttcat
     3241 cctcgattag tccccagtta ctggcaaagt caggatgatt ctctaaaaaa atacgttctg
     3301 tctgaaaagt gactgaccga atggggaaag aagctgtttc tctctcaaaa ctagtaaaca
     3361 atgcacgcgc aatcccctga cggcgatgac ctggatgaac caatatcgtc acttctacat
     3421 cttggtcatc tgcatagaca gttaataaac caacaagttt gcctttttca taataaagga
     3481 aaaaggcggg catgtttggg tcaaaattaa gcatgttaga gagataggga tcgcgatagg
     3541 taccgtcata gttttggcaa cagttaatta cttttttcgc ctcagatagc tcctcttggc
     3601 ttaacttgtt tcttgcttga atcatatagg tatcctctac aaaccagacg atctgtgact
     3661 ggcatcttta gcctgctcga gtttattgac ataatactcc cgtttttctt cgacttcgtg
     3721 aataacaggc tcatctttct taccatgaag acggacaatc ttggccggaa taccgacaac
     3781 cgtcacatca ctaggtacat ctgctacgac aactgctgca gcaccgacct tggcattttc
     3841 accaatttcc acaggcccga taacttgggc atgggctgat atgagggctc cctttcgtac
     3901 agtcggatgg cgtttgccac agtctttccc tgttcccccg agagtcactc cgtgatagag
     3961 aagaacgcct ttttcaacaa tcgctgtctc tccaatcacc agaccagaac catggtcaat
     4021 aaagacacct gaatcaatct gggctcctgg atgaatctca atctgagtcc aaaagcgcca
     4081 aaactgactg tgcatacgag ctaagagttt gaagtcgtac ttccagagaa aatgcgagag
     4141 acggtgggcc gccaaggcct tgacacctgg ataagtcagc aaaacctcca aagtggtgcg
     4201 ggccgctgga tcattttctt ttacgatatc aatggtttcg tgccaccacc ccatacattt
     4261 ctccttttct tactctgaat cttttggtgt ttctgtaaat tctttcttag gtttgtgatc
     4321 cttgtgatga cgtgggcggt gagggcgctc agacttttca cctttttcat catgctcagg
     4381 ttttggcgga cgaggtagaa gagccttcat agaggcatcg atacggcctt tttcatcaat
     4441 cttgataacc ttaacatcaa cttcatcccc gatttctacc aaatcctcta cacgattggt
     4501 acgagtccaa gccatctcag agatatgaac aagggcatct gtcttatcaa agaggttaac
     4561 aaaggcacca aatttctcga tacgaacgac tttagcacgg taaacttcat ccactttggc
     4621 ttcacgaacc aaaccagcaa taatttcttt ggcacggtta atagcatctt ggtcactaga
     4681 gtagatagac acatttcctt cttcgtctat atcaatctta acacctgttt cagcgataat
     4741 cttgtcgatg gtttctccac ccttaccgat gacaatctta atcttgtcca catcaatctt
     4801 gatcgtatca attttcggag cagttggagc caattctgga cgaacttctg gaatggttgc
     4861 ttcaatgaca tcaaggattt caaaacgcgc tttcttggct tgagcaagag cctccgtcaa
     4921 gatttctgca gtaatccctt gaatcttgat atccatttga agggctgtaa tcccatcacg
     4981 agtacctgca accttgaagt ccatatctcc aaagtgatct tccaaacctt ggatatctgt
     5041 caatactgtg tagttatttc catctgagat aagtcccata gcaataccag ctactggcgc
     5101 cttgattggc acaccaccag tcataagggc aagagttccc gcacagatag aagcttgaga
     5161 tgaagaaccg tttgattcca aaacttctgc tactagacgg atagcgtatg ggaattcttc
     5221 caagcttggc aagacttgag caagagcacg ctcaccaagg gcaccgtgac cgatttcacg
     5281 acgacctggc gcaccgtaac gacctgtttc ccctacagaa tattgaggga agttatagtg
     5341 gtgcataaag cgtttcttgt actctggatc caaaccatca atgatttgag tttctcccat
     5401 cggagccaag gtcaagactg aaagagcttg agtttgccca cgagtaaaga gacctgaacc
     5461 atgtacacga ggaaggaagt caacaaccgc atccaaagga cggatttcat cgaccttacg
     5521 accatcagga cgcaccttgt cttctgtaat taaacgtcgc acttctgcgt gttccatttg
     5581 ttccaagatt tcagccacat cacgcataat acggtcaaat tcttcgtggt tcgcatattt
     5641 ttcttcgtaa acggcagtca cttggtcttt cactgcttga gttgcagctt cacgggccaa
     5701 tttctcttct acttgaactg ccttttggag gtcactgttg taggctgcaa tgatttcagc
     5761 ttgcaattca gcatccacgt gaagcaattc cacttctgct ttttctttac cgacagcagc
     5821 aacgatttct tcttggaagg caatcaattc tttgacagct tcgtgccctt taagaagcgc
     5881 ttccaacatg atttcttctg acaattcttt ggcaccagac tctaccatgt tgatagcgtg
     5941 cttggttcca gctactgtca attcaagaag agattgctct gcttgttctt gacttgggtt
     6001 gatgatgatt tggccatcta catatcccac ttgtacccca gcaattggtc cgtcaaatgg
     6061 aatatctgaa atagacagtg ccaaagatga accaaacata gcagccattg gtgcagatgc
     6121 attttcatca taagaaagca ctgtattgat gacttggact tcattacgga aaccttccgc
     6181 aaacatagga cgaatcggac ggtcaatcaa acgcgctgtc aaggtcgcat ctgttgaagg
     6241 acgtccttca cgtttcataa agccaccagg aaacttccca gccgcataca ttttttcttc
     6301 gtagttgact tggagtggga agaaatcccc agttgccatt ttcttagaca taacggcagc
     6361 agtcaagaca gttgactcac cgtaacgtac gacaacagag ccatttgctt gcttagcaac
     6421 ctgaccagtt tctacaatta actcacgacc cgcaaaagtc gtttgaaaca cttgttttgc
     6481 cattttaatc ccctttggat tgatgaaatt atacgccttg cctacaaaga tcaagatacc
     6541 aaggacgtca aaagcaaagt aaaaatagga aactgacgaa gtcttcgatg aagacaagac
     6601 agtttatctt ttttacacag cttttcggcc gtgttcaatt acacaagata ttttggacgg
     6661 ttcggcttgc cgaacatttc tgtagaaaaa taggaaggtg acgtcacact cgacgagtgc
     6721 taggaagctt atcttttttc ctaagaaatg agaccaaaat tcaagtcatc aagataccaa
     6781 gccgtcaagc aactcaaagg aagataggaa atcgaacgac ggagcgacta ctcctaggga
     6841 gatttatctt tttccacaga gttgtaggca agttcagttt tcaagataca tcattagaaa
     6901 ggtttaatac taaagtatct aaagctttca cgctaatcgc tatcgggcga ttagctaaat
     6961 gctttactaa ctctctcgtc aaataacatc gatttgactc actcgtgtcg ttaaatctta
     7021 cagtttaaat gcattgtatt atttaatacc ttcatctttg tatcaagtac gtacagaatt
     7081 tattttatca tatttttctt aaaaagtgag gtctttacca ttaaaaagga accattcccc
     7141 tcacctgaga agaatggttt gcttttatta tcctagagac tggtgattaa acaaggcatg
     7201 ggttgcttga tggatgtatt ttgctgtatc agcattattc atcgtataga gatgcacacc
     7261 ggcaacatcc tgagttacca agtccacgat ttggtccact gcataggcaa gtcctgctgc
     7321 tctgagcgac tcagggtcat gctcatactt gtctaagatg gctttaaatt tgcgtggaag
     7381 atggatattc tcacaagtct tcaagagtcg gagagcctga tttcgattca gaattggcat
     7441 aattcctgca tgaatgggaa catcaatccc agccaagata cacttgtcct gaaaatcata
     7501 gaagcgctca ttgtcaaaga agagctgagt tacgaggctc gaacagcctg catccacttt
     7561 cttcttaaga ttttgaatat ctgaaatctg atttggcgaa tctggatgcc cttctggata
     7621 gcaagctcca ataatatcaa agtgaggggc tcgttccttg ataaactcaa tcaagtcggt
     7681 tgcatagcgg aaatcctttt gtggttccac gtctggaata atatccccac gaagagccaa
     7741 gattttctgc accccaactt tgtccaagtc agcaatagtt tcagcaacct tgtccttagt
     7801 tagataaata gctggcaagt gggcaatggt cggaatcgcc aaatcatttt ggataaagtc
     7861 agccaaacga accgtcgttt ccttgatatt aaatttatta ttgctggcag ttacactgat
     7921 aaaatgggga accaactcct gcatatcctg caaggctgaa ataatgttat cattacccac
     7981 ggctgggttt ggagggaaca cttcaaatga gagtgacggt gtttggcgtg acatatgtaa
     8041 taaccttttc tagttgattt ctttttgaac aaccactgta tggagagaaa tccaatctta
     8101 caatttctca cgcgcagctt tagctgcttc aacaaggcgg atcaagcttt cttttgtttc
     8161 tgggatacca cgtgttttca aaccacagtc agggttgatc caaactttct tgcttggcac
     8221 tttagcaagg atggcttcga ttgtgttgtc gatttcgcct tcatttggta cacgaggtga
     8281 gtggatatcg taaaccccag gtcccacttc tgtttggaag tttttcgctt tgagttcgtc
     8341 caagatttca aggtttgaac ggctagcttc aaaggaaata acgtctgcat ccatgttatc
     8401 gatagctggg atgatatctg taaattctga gtaacacatg tgagtgtgga tttgtgtgtc
     8461 tggcgctact gttgagtgta ccaagcggaa ggcaggaata gcccagtcaa ggtagtcttc
     8521 gtaccagtcg ctacggcgga gtggcaattt ttcacgaaga gcagcctcat caatttggat
     8581 gattttcaca ccagcagctt caaggtcaag cacttcatcc ttgatagcaa gggcgatttg
     8641 aagagttgaa tccttgatag agatgtcttc acgtgggaat gaccagttga ggatggtaac
     8701 aggtccagtc aacatacctt taacaggttt gtttgtacgg ctttgtgcat agctagacca
     8761 tttaacagtg atagggttaa gacgagtgac atcaccccag atgattggtg gtttcacccc
     8821 acgcataccg tatgactgta cccaaccatt tttagagaag aggtatcctg acaagttttg
     8881 accgaagtac tcaaccatgt cattacgctc aaattcaccg tgaacaagga catcaaagtc
     8941 aatatcttct tgccacttga tccattcgtc aatcgtttca gcaaggaaag catcgtactc
     9001 tttttgagac aattcacctt tacggtaagc caaacgtttg gcacgaactt cttttgtttg
     9061 agggaatgaa ccaatcgttg ttgttggaag agctggaagt ttgaaagctt cttcttggat
     9121 agcttcacgt tctgcaaaga ctggcaaacg agtgtagtct gcgtctgtca agccagcgat
     9181 acgcgcacga agttcagcat tttcaccaac acgctcagtc gtaaagagtt ctttgttggc
     9241 tgcaagagct tctgaacctt gaccattgcg gatagcatcc aagtcacgga tttcatccaa
     9301 tttttcaact gcaaaggcaa agtggttcaa gagtgctggt tcaaattctt cattagcagt
     9361 tgtaaatggc acatgaagaa gtgagcaaga gcttgtcaaa acgatgtttt cagctgggat
     9421 ttgctcaaga acagccaagc tcttttcgta gttgttgcgc cagatgtttt taccattgac
     9481 aatacctaca tagagagtct tgtcagctgg gaagccacct ttaacgagtt caagagtttt
     9541 cttaccttca acaaagtcaa gaccgatagc atctactggt aagtttacaa ggtcagcgta
     9601 tacgtcacga acatcaccga aataagtttg aagcaagact tcaagacctt ttttgtcagc
     9661 caagagtttg ttgtaaaggt tcaagaagag agctttttct tcagctgtca agtcttttac
     9721 aagagccgct tcatccaatt ggatgcgagt cgcaccaagt tcagccaatt tagcaaaaac
     9781 ttcttggtaa gcagccacta agctatctac gaagtcgtct gctttcacgc cttcttcaaa
     9841 gtctgacaat tgaaggaaag tgaagggacc tacaagaaca ggacgagtgt tcaatccaag
     9901 ttctttggct tcttggaact catcgaaaat cttgtgacca gccaatttta cttgagtgtc
     9961 tttttcaaat ttaggaacga tgtagtggta gttagtgttg aaccatttct tcattggaag
    10021 ggcgcgaacg tccccttttt ctccctggta accacgtccc aaagcgaagt agcgctcaag
    10081 gtcagacaag tccaagtttt gaacggatgc aggcaccacg ttgaaaagga aagccgcatc
    10141 taggaagtta tcatagtgag aaaagtcatt tgatggaatt tcagtgatgc ctttttcttt
    10201 gacaatgttc cagtgtttag cacgcaagtc ttttgctgct gataaaagtt cttcctctga
    10261 gatttctttt ctaaagtatt tttcagttgt aaattttaat tcacggaatt cgcccaaacg
    10321 agggaaaccg acgattgtag ttgacatgat gtgtcctcca aaatttgttg ttgaaactat
    10381 cttaacagaa aagaaagcgt ctgtataatt gtaaaaaatt agggtttgat atagtttgaa
    10441 actatatatc tgtttcggac aaaagaaaaa gacttgaagc aaacgtctca aatcctttgt
    10501 atagcttgtt ttatagctgt attttagtta gaatgctcaa acgcgttatt agtaattctt
    10561 ataagtgact atggcttgtt attagaaaag actataactg attctagtca actttttccc
    10621 tgttcaagtg ggacgattgc tagtgtcttt cctaaactgg ctaggacttt taagactgta
    10681 tccaactgag gactagtctt tcctgtctcc atcctagcta tgacaggctg gcttattcca
    10741 ctgacttctt ccagcttttt ctgactgatt ccttgttcat acctagcctc aatcaactcg
    10801 ctcatgatag ccactcgcat atcactttca aggatttcct ccttgctaaa gagctcagat
    10861 ggacatcctt ccaattactc ccaatagcac tattcttcat cacttaaccc tctttttttt
    10921 acgtctatgt atttttaaaa aaatgagcga attatgattc gatagattga tcagcgggtt
    10981 taaaattggg actaacttgt ttcttaacag attttccttt tctaggataa agcaaatcct
    11041 gtttgcttaa ccccaacttt ccatgatgaa tccaatagta aatggttgaa attcccacgt
    11101 taaccccttt agccatcacc atcatttcag gcaaaaattt ttggttatgt atagtggaga
    11161 atcttttcct ttagttcctt ggtcaagctt gatttcttga ccgagcgctt gcgattgttt
    11221 tcataagact gttgagcgta gtcggcagaa taaacctctt tgaagcgccc ttttccaaga
    11281 cattttcgga ctgtcccacg cttgatttca gtgtggatag tttgaggagc ttttccaagt
    11341 agagaggcaa cttctctatt tgattttcct tcttttttcc atctttcgat taagcgacgg
    11401 ctatcgattg tcaaatgttt accttttgta gtataattgt cttgcatctc tgtgcctttt
    11461 aatcatttca atcttaaatt ggactttttt tacttgggtt gtacttaatc tataaggaag
    11521 acaagaaaaa gaatatcaat caagtaaagt cacaaagtca cattagctcc gagcaaccat
    11581 tgcaaattga ggtactcaca caatgattaa aacatttctc tctgcccttt cggtcattct
    11641 ctttgttatc cctatcataa cttattcttt ttttccatct tctaatctta atatttggct
    11701 atctaccaga cctatcttgg cacagattta tgccttcccc ttagctactg caactatggc
    11761 tgccatttta agtttcgtat ttttttccct atctttttac aagaaaaata aacaaatacg
    11821 gttttactct ggcattttgc tcttattatc gctcatatta ctattattcg gaacagataa
    11881 aaccctttct tccgcatcaa ataagactaa aaccttaaaa ttagtaactt ggaacgtcgc
    11941 taatcaaata gaagcacaac atattgagcg aatttttagc cattttgacg ccgatatggc
    12001 tatattccct gaactagcta ccaatatcag aggtgagcaa gaaaaccaga gaatcaaact
    12061 attgtttcat caagttggac tttctatggc caactatgat atttttactt ctccacctac
    12121 tgacagtgga atagctcctg tgactgtgat tgtcaagaaa agttacgatt tctatacaaa
    12181 agctgaaact tttcatacaa cacggttcgg gacaattgta ttacattcga gaaaacaaga
    12241 tataccagat atcattgctt tgcatactgc tcctcctctg ccaggtttaa tggaaatctg
    12301 gaagcaagac ttaaacatca ttcataatca attggcttca aaatatccaa aggctattat
    12361 tgcaggtgat tttaatgcaa ctatgcgtca tggagcactt gcaaaaataa gctctcatag
    12421 ggacgcatta aatgcactgc caccttttga aagaggaact tggaatagcc aaagtccaaa
    12481 actttttaat gcaacgatag atcatatttt attgcctaaa aaccactact atgttaaaga
    12541 tttagacatt gtaagttttc aaaactctga tcatagatgt atttttacag aaatcacatt
    12601 ttaattattt tatataaaat cacccctcta gtgttcataa actagagggg gaatttatat
    12661 cctactatcg tttaacgcac ttctgcattc actttttctt cgagcgatgc ttggattttt
    12721 tccatatagc gtgcgacttc ttcgtccgtt aagctatctt ctggattttg gaaggtcaag
    12781 ctataagcca tggacttcat accaagtccc aatttctcac ctgagaagac gtcaaagagt
    12841 ttgatatctg tcaaacgttt cacgccggca gcttggatag catctacaac ttcttggtga
    12901 gttacttctg ccttgaggag aagggcaacg tcacggctga ctgctgggaa tttcgtgatt
    12961 tccacaaatg gaacagcagg ttggagcgcc ccttcgatgg ctgaaaggtt aagctcagct
    13021 acatacgttt ctggaatatc gtaagccttg gcagtgactg gatgcacttg gccaagaaaa
    13081 ccaagaactt ggtcaccgag tgaaatgact gctgtacgtc ctgggtgaag gctggcaatc
    13141 tcagctgttg ctgtataggt cacttctagt cccaagcgag taaagagcgc ttcaaggatt
    13201 cccttagcat agaagaaatc aactggaact gctgctgttt ggaaatcttt ttcagcaacc
    13261 aagcctgtca aggcaaaggc aaaactgttg atttcatttg gaagttcttc ttttggatta
    13321 cctgtttgtt caaagacttt tccaatctcg taaagggcca agtttttatt cttacgagcc
    13381 acgttgtagg caacggtatc aaggatacct gaaatcatat tttgacggag gactgaacga
    13441 tccacagtca ttggccacat gagttccgta aggttacttg gttgagccgt aaactcaact
    13501 gctttttcag gagttgttag agtataggtg atgatttctg tcaaacctgc tccttcagca
    13561 atggtacgaa cttgacggcg gagtttttgt gtcacagtca attcaccagc tgtaccatcg
    13621 tcttttggaa ggctggttgg caaacggtca tatccataga tacgagcgat ttcttcaaag
    13681 agatcagctt cgattgtgat atcccaacga cgacgtggta cgctgactgt aaagctgtct
    13741 gcatttccag aaagaccaaa gccaagacga cggaagacgt cttcgacatc agcataagac
    13801 agctcagttc cgaggacacg gttaacatca gcaagagttg aagaaacttc tacatctgaa
    13861 gtatcaagct cacccgctga aacgataccc ttacgcaccg tcgcacctgc aagttccgca
    13921 atcaggctag ctgccgcatc aagggcttca ttaactgttg ccacattaat tcctttttca
    13981 aagcgagaag atgactcaga acgaaggttc aggcgaccac ttgtcttacg gatagatttg
    14041 ccattaaaaa cagcagcttc aaggataaca cgactagatt tttcagaaat ttctgtagcc
    14101 tgaccaccca taacaccggc aagggctact ggtttgtcag caactgtaat cacgaggtct
    14161 gtctcagcca agtctcgttc ttcaccgtcc aaggtcacca acttttcacc agcacgcgct
    14221 tcacgcacac ggatgtcagt cccttcaaat gtgtccaagt caaaagcatg cataggttga
    14281 ccaaagtaga gcaggatgta gtttgtcacg tctacaacgt tattgatggg acggatgcct
    14341 tcgttcatga gaaggttttg caaccattgt ggacttggtg cgatagtcac attgtccaag
    14401 atacgagctg catagtaagg cgccttgtct gtcccaatgc tgacagaaag ggcatctgcc
    14461 gcagattcat tagtttctgt tagagtaaat tctttaaagt tgactgcctt gtcatagatg
    14521 gctgccactt cgtgagccac tccacacata gaaagggcat ctgcacggtt tggtgtgatg
    14581 gaaagttcga tgatttcatc atccaagtct aggtaagaaa agacttcctc acctggcacg
    14641 gcattttctg gcaagatttg gatgccatct gcgaattcct taggcacaac tgagtcagaa
    14701 attcccaatt caccaagtga acagatcatt ccaagtgact ccaaaccacg gatttttcct
    14761 tttttgattt tgtagttatc agcgatacga gctcctggaa gagccaccat gaccttgatc
    14821 ccagcacgca catttggggc accacaaacg atctgacgct cttcttcttc gccaacgtta
    14881 acctgacaaa catggaggtg agtctctggc acatcttcgc aagacaagac ctcaccgacg
    14941 acaatttttg agagaccagc agctggtgat tcgacaccct ctacctcgat tcctgtagtt
    15001 gacatttttt cagccaactc ttgtgatggc acatcaatgt ccaccaattc ttttaaccat
    15061 ttataagata caagcataat ttagttctcc agaatgacag ttgtcactct agttcttttc
    15121 ctttcctatc atttcaatag aagaatcctc ttcttacctt aatttctttc tcagtaacca
    15181 atccgtatct actttttgac caaccataaa atgatgttgg ctaaattttt caaaaccata
    15241 tcgattataa aacgcttgag cttttgtatt atgctcccaa acacctaacc aagcccaaga
    15301 aaaactattt tttgtagcaa gttcaagtgc gaattcaaac agttgcttac ctagtccaaa
    15361 tccttggaat ttttgtagca catagaggcg ttgaatttca aaagcgtcct ctaattctct
    15421 ctcagtttga gcacttcccc agttgacttt gagaaaacca gctatctcct cctcatgcat
    15481 aatgaaatag gtttcagagt caggatttcc caactcagtt gacaaagttt tcagactata
    15541 agcctcttca aagtattcct gtaactgctc ttccgtatta tcatacgcaa aggtttcacg
    15601 aaaggcttgt ttggcaattt tagccaacac ctcaacatct gccatttcta cttttctaat
    15661 cattatttaa actgttctga gaagcggaca tctccttggt agaatccacg gatatcgttg
    15721 attccataac ggagcatagc tacacgctct tgtccaagac caaaggcaaa gccagagtat
    15781 acagtcgcat cgataccact catttcaagg acacgtgggt gaaccatacc ggcccccata
    15841 atttcgatcc aacctgtttt cttacataca ttacagcctt ctccaccaca cttgaagcaa
    15901 gaaacatcca cctcaacaga tggctctgtg aatgggaagt aagatggacg caaacgaatt
    15961 tgacgctctt caccaaacat tttttggaca atcaactgaa gcgttccttg aagatcagcc
    16021 atagagatat ttttcccaac taccaagcct tcgatttggt ggaattggtg actgtgggtc
    16081 gcatcgtccg tatcgcgacg gaagacacgc cctggcgaga tcatcttcaa aggaccttta
    16141 gaaaaatcat gggcatccat agcacgcgcc tgaactggag acgtgtgggt acggagcaag
    16201 atttcttcag tgatatagaa agtatcctgc atatcacgag ctgggtggtc ttttggaagg
    16261 ttcatacgtt caaagttata gtagtcttgc tccacttcaa aaccatccac gacttgataa
    16321 cccataccga tgaagatatc ttcgatttct tcactggttt gtgtcaaaac gtgacggtga
    16381 ccagtcgcaa ctggacgacc tggaagcgtc acatcgatac tctcgctagc cagttgagcc
    16441 gcgactttct tttcttccaa gagcttagct gtttcttcaa aagcagcagt caagacatca
    16501 cgagcttcat tgacgtgttt cccgatgatt ggacgcatct cagcagaaac atctttcatc
    16561 cctttgagga tttcagtgag cgaacccttt ttaccaagga cagagacacg caaatcttgc
    16621 atctcttttt catttccagc agtaatctgc ttcaagctag ccagcgtttc ttcgcgaagc
    16681 gcttttaatt gttcttcaat agttgacata tttcctccat cagtctctcg tagataaaaa
    16741 gaaaaccaca tgccaaaaac tccactcgga gcgttgacac gcggtaccat ccgttttcat
    16801 ctgacaagtc agaccttcat ttctaaatcc atgcgcaagt gaattcaccc agctttcata
    16861 tagagagctt gcagtcacgg ctctcctccc tgatatactt cccttgggct actagtcttt
    16921 cagattccta ttcaattact acttagttta tcagattttt accattcttg caagacctat
    16981 cttacttctg cttgttagct tattcttatc taactttata gcggattgaa ataagatgag
    17041 aacaaatcga ttgggaaagt aaaattaatt tctataaatg ttttagcaat tgtttcgtac
    17101 tattttagat tcagtctact atacataaac taacctcctc attattagca aggattctac
    17161 tgattataac ctaattctta gactacttca agactaactg tccaataata atctacagat
    17221 aaatcatcca ctcttaataa aattttattc aatccatcta ctcattccca aaaggttgag
    17281 atttatctag taactctaaa acattaatgg taggtagcaa cattgcttca ctgctatcaa
    17341 ttgccgaaac tattgaaaca atagaacgta aataatgata aagaatagca gtaccattta
    17401 cgtatagaat atcggtgata ttttcatcta tatttatttc aaaatatcct attacagtta
    17461 cagatatttt tttcatggca tctttgtcaa ctaaagaaac actaagtttt acggctccat
    17521 gactataatc atctgtatga ccaaccttaa ctatgggata taatatatcg aaggtaaatg
    17581 tgaacaaact gattaggaaa tttaaaccaa cttctaacaa tctgttatac tcaatgaaaa
    17641 ccaaagagca aactaggaaa ctagcctcag gttgctcaaa acactgtttt gaggttgtag
    17701 atggaactga cgtagtcaga tcaaaacact gttttgaggt tgtggataga actgacgtag
    17761 tcagatcaaa acactgtttt gaggttgtgg atagaactga cgaagtcaga tcaaaacact
    17821 gttttgaggt tgtggataga actgacgtag tcagctcaaa acactgtttt gaggttgtgg
    17881 atagaactga cgtagtcagc tcaaaacact gttttgaggt tgtggataga actgacgtag
    17941 tcagtaacca tacgcacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    18001 attagaaagc tcgatgaact attccagatt cattccacta aatttcgaaa tcgagtaggg
    18061 gataatctct agcccctctc acaccaccgt acgtgccgtt cggcatacgg cggttcaact
    18121 aacttttaac gcatgtcgtt caaggtaata atccaaacac gaaaccagtc cacgtttttc
    18181 aaggactggt tttgatatag cacgtttaag taccgacttc tgagctacta attgatagtg
    18241 gtcgccccag ccagatacct tatccgctat ataggcctta ttatcacgtt cctgttcgta
    18301 gagccacgat ttcgctatcc cttcctctga cgattcttat ttccagcgtc agacttaaaa
    18361 cggtctatcc ccagaccgtt ttaatccgct acctcacgat agtcagactt gggaatcgct
    18421 attgggttca ccggtagtag gtgcccaccg aggacttaca cctcagatat acgacatgcc
    18481 cgtcgtacat caaaaaaagt tgagacatag tgtcttcaac ttttttacat tactttaact
    18541 actgattaaa gtgagtttac gtcaactttg ataccaacac cttgagtagt tgtgatagtc
    18601 aagtttgtta cgtaagttcc tttagctgta gctggttttg ctttttggat tgtttcgttg
    18661 aaagctttaa agttttcaac caatttttca gcttcaaatg atactttacc gatgattgct
    18721 tgaacgttac ctgcacggtc agcacggtaa gtgattttac cacctttaga ctcttcaact
    18781 gctttagcaa catccattgt tacagtacca gttttagggt ttggcatcaa gttacgtggt
    18841 ccaaggacac gtccaagacg tccaacaaga gccatcatat caggtgtagc gataactacg
    18901 tcgaagtcca accaaccgtc gttgatttta gcaacaaggt catcttcacc aacaaagtct
    18961 gcaccagcag cttttgcttc ttcagctttt gcaccacgtg cgaaaacaag aacacgtgaa
    19021 gttttaccag taccgtttgg caataccatt gctccacgga tttgttggtc agctttttta
    19081 acgtcgatgt tcaagttgta agcaacttct acagttgcat caaattttgc aaagttagtt
    19141 tcttttgcaa gtgctacagc ttcttctaca ctgtatgctt ttgtgctgtc gattttctca
    19201 agagcagcac gaagttgttt gcttttttta gccattttct attctccttg taagtggttc
    19261 aatcgatttt catctcccac gtcacttctc gaaatgatga agtcttgcgg gttttcagtc
    19321 tactattttt ctcttcctac ggccttaagc tcccttgctg tacccaagta caagcctcag
    19381 tcacttgcct agtatgaaaa gcaactaata gactgctgtg agattttcta ctgtgttatt
    19441 gattagtcaa caacagtgaa tcccatagaa cgagcagtac cttcgatcat acgcattgca
    19501 gactctacgt ttgctgcgtt caaatctggc atcttagttt ctgcaatttc ttgtacttgt
    19561 gcacgagtaa ctgtagcaac tttagtttta ttaggtgtac ctgatccttt ttcaacacct
    19621 gcagcttttt tcaaaagaac agcagctggt ggtgttttcg taacgaaagt aaatgattta
    19681 tcttcgtaaa ctgagataac aactggaatg atcataccag cttggtcagc tgtacgagcg
    19741 ttgaactctt ttgtgaatcc catgatgttg ataccagctt gaccaagagc aggtccaacc
    19801 ggtggagctg gtgtagcttt accagcaggg atttgcaatt ttacaagttt ttcgactttt
    19861 ttagccattt ttaaatcctc ctttgtggtt ttggcggtaa ttagagattt ttacctccca
    19921 caagtatgtt tttcacatac ccatccatta tacactattt atctggaatt gcaagagaaa
    19981 agtttatttt ttgtactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg
    20041 ctcaaagtac agctttgagg ttgcagataa aactgacgaa gtcagctcaa aacactgttt
    20101 tgaggttgtg aatagaaccg acgcagtcag taggtaaggc gacgctgacg tggtttgaag
    20161 agattttcga agagtattaa tcgacgtagt ctccgccttc aaagccatag tattcttcca
    20221 aactgagacc acttgcagca atttctttag cttcttttcc tacataacgc aggtgccatt
    20281 cttcagccat atagcctgtt tccttttcct tgcctttgag ataacggaca acaaagccat
    20341 aatcagctgc atgatccaag agccattggg ctgctttttc ttctgtcacc aaatcaccat
    20401 cagtcccaat cacatcaaag gccaagcctg tctggtgttc gctatagcca ggacgggcag
    20461 agtaacggtc agctgctgcc tttccatctt ggttgacata atcttgatag agcttggtct
    20521 gagtttcata acttctaaaa ccactgtaat gatcactaat agggaaacct gcctcttgca
    20581 tcgctttgat gagtttgacc aactctgcct tggctgttgg attttcccct ggattatagt
    20641 ctttagacaa tggatagtgt ttgttggcta cgatgatttc atcgtatttc ccttgaatgc
    20701 tgtagtaatc acctttattg accacttctg ctttcttctg ggcagctcct tgagacttac
    20761 taccgactgt tccatcagct ttggctgtct gttctgtctt agtttctcca tcttcatttt
    20821 ttgttttttc ttgtgaacaa gctgctagac tcaaggctag caaagctgtc aagactaggt
    20881 atcttttctt catttctact cctttatttc taatagttta tctacttctg acgataaacg
    20941 tttgactaat cttttaatct catccggttt tgcttggcag gtttctgctg tcatttcttc
    21001 aaagggaacc caccagactg gtccacgacc cttgagacca tgaccattca tatcacctgt
    21061 ccgtcgtgga aacagatgcc aatgaagatg agcatcgcca tttcctagca gttcgatatt
    21121 cattttctca gcagcaaagg ccttggcaac tgcctcttgg actaaactca tttcttctag
    21181 aaaacggagt cttgtctcct ttttcaaatg gtgcaattcg ctgacatgct ccttggctag
    21241 aaagagacta tagccttcaa aatactggtg gtctccaacc acaagatagc ctgtttccaa
    21301 ctctttgaca aagtaaggat tttcttcctt cttgatgagg tcaattctct gacaaataag
    21361 gcacatatta gtccaccaac gtgctcttaa gataagcatc gaccattcgt tctgttgcga
    21421 tcaccgagtc aatatgggta cgctcatagg aatggctaga ctctatacca gcaccgagaa
    21481 gggcgtgttt gacttctgcc cctgcagaca tagccgctga agcgtccgaa ccataaaatg
    21541 gatagatatc cagcttaaat ggaatatctt gctctttcgc caaagccacc aaatgttgac
    21601 ggaagtcata gtgataaggt ccagaagcat ccttgacaca gatagacact gtatattcgt
    21661 ctgtttgctg gtcatctccc atggctccca tatccacagc cagatattct actacctgag
    21721 caggaatgtt agagtttgca ccgtgtccca cttcttcaaa gactgaaaaa gcaaaatgag
    21781 ttgttacggg caattcaatc ttctcttcct tataaatgcg aaggagattg agcaaaatcg
    21841 ccgcactgac cttgtcatcc aaatggcgag acttgataaa acctgtctct gtcacgacag
    21901 ttcgtgggtc aaaactgata aaatcaccga cctcaatgcc aagagcacga gtttcttttt
    21961 cactagttac tttggcgtcc aaacgcactt ccatattgtc ttgcgtgcgt tctgcagttc
    22021 ctgcatcctt atagacatgg caagaagttt ggtggatgag gatggttcct gatacttttt
    22081 cacctgtgct agccacatga atggtacagt tttctccttc aatcatgttc caaggaaagc
    22141 caccgatacg gtccattttg agacggccgt ctggtttgac agcacggaca atagcaccaa
    22201 gcgtatctac atgggcagtc acatagcgat gttgctcatc attttgacct ttaatagtta
    22261 cattgacacc gcccttggat gtgcgaaccg gctggtaacc aaaaccttct agagtcttaa
    22321 ctaaatagtc cgcaatctca cgagtaaagc ctgttggcga cgcaatggct gtcagttctt
    22381 tgatatattc tactgtttga ttcatttctt cacctctttt gctacctatt ataacacatt
    22441 tatcatcgga taaaaaaaga aaatcactcc tgtagacttg actacaaaag tgattttata
    22501 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggctgtactt gagtacgaca
    22561 aggcgacgtt gacgcggttt gaatttgatt ttcgaagagt attagtgatt attccatttc
    22621 aaaaacatcg ctttcttgct tgtttggtag aaccaatgag agcaagattc caacaatggc
    22681 tggcaccaac catgggagag atgccttggc aaaaggaaga acgctaacaa gatttgcaag
    22741 aaactcaacc ttaaacgagc ttcctagtac gcttgcaatg gcaataactg taaccacagc
    22801 aattgtcaac tgcatacctg gttttgaaag agcaacaaat ttgttgacaa tgacaatcat
    22861 aacgatagca atcgtgattg ggtacaagat aaccagtact ggaattgagt acttgataat
    22921 cgcatcaaga cccaaattgg caatagcaaa tccaatcaag gtaaaggctg tcgcataaac
    22981 cttgtagctg atttgtggga agcgctcatt aaagaactca gctgttgaca caatcaaacc
    23041 aacagtcgtt gtgaagcagg ttacggtaac catagctgca aggaagagtt gagctgttga
    23101 gccaaagatt tcttgagtgg cttgtgacaa gatgtaaaca cctggtgttc cacccttcat
    23161 cgcttcagct ggtactggga aatgatttcc aagaaaacct aaaccgatgt aaagagcgct
    23221 gaaggcaagg gcaacaacga taccaacaac ccaaatagtt gaaatgtatt ctttcttact
    23281 tgaaaatcca agttgtttca aggtttgaac tgcgattacg ctaaaggcca ctgaggcaag
    23341 ggcgtccaag gtattgtaac cttctaggaa acctgtacca aaggcagaag cttgataagc
    23401 agctgaagca gcttgaggac ttgttccacc atatttgata gctcccagaa cgaccaagat
    23461 aacaatcaaa attgcaaaga ctggcgttaa aatacgtcca atgcggtcta agatttttga
    23521 tggattaagc gaaatcaaat aggctgccgc aaaatacaga accgtaaata caatcaagcc
    23581 aagtccttta tttgcatccg acaaaagggg gctaatccct acttcgtaag ctgttgtagc
    23641 agtacgtggg gtagcaaaga atggaccgat tgacaagtaa agaactgaga ggtaaagagt
    23701 cgcaaaccaa ggcgctatct tcgttgaaat ctcgtagata taccctttag gatttagcgt
    23761 tccaataata agggtcaaga cggcgatacc aacgcctgaa aagacaaaac ctgcgatggc
    23821 aggaagaaaa tgttctccag atagagcacc tagagaaggc ggaaaaatca agttccccgc
    23881 accaaaaaat attccaaaca ggagcaaacc tgttagggta ccttttttag ccataaaaat
    23941 ctccttcata tttataaaat actgacctag tataccacga ttaggagtct gaaaaaagca
    24001 tcacgaggca aatattaaat gttttcaatt ttcttaaaaa taagaattat ctaaaaataa
    24061 aactctccta cccagtccac accaagtagg agaaatgcaa aattttaaag ttcttcaaag
    24121 gctaacatgc caccctggac attgataaca ttataacctt gttctaacag gaattggcaa
    24181 gcacgcgccg atctcattcc agatttgcaa ataatataat gcaagcgatc tttgtccaat
    24241 taatcataac tatcagtcaa ttgactaagc ggtaggttgt gggcaccttc taaatgaaga
    24301 gctgcaaact catccacttc tctcacatcc actagagaaa gctggtcgtt ttggtaaagc
    24361 tggtaaaatg cgtcaaaggc tatttctttc attctttttc ttctaatact cttcgaaaat
    24421 ctcttcaaac cacgtcagcg tcgccttacc gtgcgtatgt taccgacttc gtcagtttta
    24481 tctgcaacct caaagctgta ctttgagcag cctacgacta gcttcctagt ttgctctttg
    24541 attttcattg actataaaat ggttttaatt ctttttttca aatctggcac tacttctgcc
    24601 tcaaaccaag gatttttggc catccagatt tgatttcgtg gtgatgggtg aactagcgga
    24661 aaataggctg gcagatagtc tttatagtgt ttcaccctct ccgttacctt cccactgatt
    24721 ttctcctgta aatagtaggc ttgggcatat tgcccaatca agagggttaa ctgaatatca
    24781 ggcaattcct gtaagagctg cggatgccat ttttctgcaa aacctgtacg aggcggaaga
    24841 tcacccgact tgccatgtcc tggaaagtag aaatccatag gcaaaacagc aaaataacct
    24901 gaattgtaaa aggtatcttc atccacacct agccagtccc gcaagcggtc accactttta
    24961 tctttccagt aaaggcctgc ttcttgagtt ttaagtcccg gagcctgacc gatgatattg
    25021 atgcgagcag tttttggcgc tgcaaagaga ggctcaatgc cacgctctgt atagctggca
    25081 ttctgtgaat ccgccatgat agcctgtttg attctttcga tttgagacat ctactttccc
    25141 tccaaaaaga agtccaagca taagatctca gacttctatc gttttatttg atcaattcgt
    25201 aaatagcttc ggcataaatt gctgctgctc ggaaaagatc atccaaggcg ataaattcat
    25261 tggcttggtg catggtatca atcgagtctg ggaacatagc accgtaggca actccgcgtt
    25321 ctagcaagcg accaaaggtt ccaccaccga tgacttgttc atgaccttta aggccagttt
    25381 gtttttcata gatattcaac aaggtttgca caagtggatc ttccattggc acatagtgag
    25441 gcgtgtgacc gtgttcagac aggctaacag aaacaactgg caagttttca aggattgact
    25501 tgatttgttc tggacttgtt ccttttggat agcggatgtt gagggcaatg gtattatcag
    25561 cacttgtttc atcgaagcgg aagacgccgg cattcataga aagagcaccc atcttttcat
    25621 ccacatgagc aatcttaaga ttttcaccct catgatcgtt caagagaatt ttacctgcga
    25681 tgtcaaggta gtctttggct ggaccagcaa agccaaactg gctgaggaag agggcaaggt
    25741 aagttgcgcc attgacacct gaagcaggca tagcaccgtg ggctgattta ccaatgatcg
    25801 tcaccttgta tttgccagct tcttcttgga gttctcctct aagtttgtgt tctgcaacaa
    25861 aggcatctag tttagcttgc aagtcagcca agtcacctga aacgactgct gttgctgatt
    25921 ctggtaccat attttcacgt aaaccacctg taaagctgtg aagacgggca acacctgtat
    25981 tttctcctgc aaagtggagg tattccgtga tatttccttt ttcaccattg atgattggaa
    26041 attcagcatc tggtgagaaa ccgaaatctg gtttggcaag tcctacgtgc tcaaagtagt
    26101 agtccatgtc tgcccagcct gattcttcgt ctgttccaac gatgaagcga actttcttag
    26161 aagttggaag acccaattct ttgatgattt tcaaaccata gtaacaagct gttgtaggac
    26221 ccttatcgtc cgaagccccg cgcgcataaa ggcgaccatc tttgatagtt ggtgtgtaag
    26281 ggtctgtgtc ccaaccgcta ccagcaggca ccacatccat atgggcaaag attccgagaa
    26341 cttcttctcc atcaccaaac tcaaaatgtc ctgcatagtt atcaacattc ttagttgggt
    26401 agccatcgcg gtctgcgatt tcaaggaatt tctccaaggc ttttactgga ccaggcccaa
    26461 atggatgctg ggcatcagcc ttgctgtcat cacgttctga attgatttcc aaaaggctaa
    26521 acaagtcagc caagaggtct tctttgcgtt tttctacttc tgctgtaaaa tcaattgctg
    26581 tcattttttc ttctttctat cttttctcga tgatttcatc tactggcaag cggtagcttg
    26641 gttccaattt ttcgtctgta taacccactg tgatcaagag ttctgggcgg aaacggtctt
    26701 cgatttccaa aacttcatta acttttgatt tgtcaaaacc aaggataata ttggaaccaa
    26761 ttccttggtc tgtaagagcg agaaccaagt tcatagcaac caaacctgca ttgagtgcta
    26821 ggtagtcgct gacttgttgt tcattgtagc gtgcaaattc agctggcaaa tttttcatga
    26881 agtattgaag ttgttcttct gagaaattgt tagcaccacc aactcgggca atcttacgag
    26941 cgcgtttggc aaggtctgta tctgtaaata gggcaatggt tacaggtgct gatgatacct
    27001 gttcaaaatt ggaaccataa gctaactttg ccagttcagc atttttctca cataccacca
    27061 caaatttcca aggctggctg ttgtgggcgc ttggcgccaa ggttgcaatt tcgatagccg
    27121 tacgcacatc ttttggatca acaggcttat cagtgaaatg cttggtcgca tgacgttttt
    27181 tatttaattc aagaaatttc ataatcgatt tccttttcta attctactgc ttccattcta
    27241 ccataatttg aaagagcttg cagggatttt tcatgattaa gtttttctat cacagacata
    27301 aaagatatat attggtttat caggaaagtt tctgataaac tagcaagtac tttacatttg
    27361 aatggagaca gtatgaaaaa atttagccta ttactagcta tcctaccatt tttggttgcc
    27421 tgtgggaatc aagctacacc caaagagtcc agctctcaaa agacaatcgt ccttgctaca
    27481 gctggcgatg tgccaccatt tgactacgaa gacaagggca atctgacagg cttcgatatc
    27541 gaagtcctaa aagcagtgga tgaaaaactc agcgattacg agattcaatt ccaaagaact
    27601 gcttgggaga gcatcttccc aggacttgat tctggtcact atcaagcagc agctaataat
    27661 ttgagttaca caaaagagcg cgctgaaaaa tacctctact cgcttccaat ttccaacaat
    27721 cccctcgtcc ttgtcagcaa caagaaaaat cctttgactt atcttgacca gatcgctggt
    27781 aaaacaacac aagaggatac cggaacttct aacgctcaat tcatcaataa ctggaatcag
    27841 aaacacactg ataatcccgc tacaattgat ttttctggtg aggatattgg taaacgaatc
    27901 ctagaccttg ctaacggaga gtttgatttc ctagtttttg acaaggtatc cgttcaaaag
    27961 attatcaagg accgtggttt agacctctca gtcgttgatt taccttctac agatagcccc
    28021 agcaactata tcgttttctc aagtgaccaa aaagagttta aagagaaatt tgataaagcg
    28081 ctcaaagaac tctatcaaga cggaaccctt gaaaaactca gcaataccta tctaggtggt
    28141 tcttacctcc cagatcaatc tcagttacaa taacactctt cgaaaatctc ttcaaaccac
    28201 gtcagcttta tctgcaacct caaagctgtg ctttgagcaa cctacggcta gcttcctagt
    28261 ttgctctttg attttcattg agtataagat atataaaagc gattggacta ccaatcgttt
    28321 ttagtttgca ttggttattt taggaaactc ttacaaaaaa tcaaaaaaat tcttcacatc
    28381 ctctacatac ctatgctttt ctattaagct tgctaatagt ttcagattgt gcctctgata
    28441 gttatcttca cgacgtagtt cttcatacat ttcgataaag ggaagcccct tggatttggc
    28501 caattctaac tcagcctcgt aatcataagc aactttacga aattggatat tgagtaattc
    28561 cccatcttca acctctatca cggcatactg ggcacggtga ttttttaacg cctcccaatt
    28621 aaaatagggc atgccaatcg accctggatt gatgatttgt tgccctttac tgccgtagcg
    28681 aagcaactgc ttgtgaacat gaccataaac tgccacgtcc gtttccgcat ctagcagttg
    28741 gtcaaatttc tctgtatcat tctcaactag caagtcacca ccatagtttt tgtcaggtaa
    28801 attatgagag atagaaaagc gcaatccgtc aatttctttc ttttccagca aaggcaagct
    28861 tcgtagccag acaatcgttg caggatccat tcgctccatc aaaaactggg tcatgcgcat
    28921 tgactggatt tctttcggat attccaaacc atattcgcca tccaagacct caaggacacg
    28981 atcatcccaa ttgcctcgaa cacttgctgt gataggaagg tcctttagca gggcgactaa
    29041 gtcatttgcg cctggaccag gaagaaaaat atctccctga agccaatatt cactggcccc
    29101 ttgattttta gcatctgcaa tcactgcttc tagcgccgtc gcattgccat gaacatctga
    29161 taaaattgcg attttatggt tcattgtggt ttccttccgt ttggtaatct actctttctt
    29221 ctgctacttg aggcaaggct tctccctgcg ggttcaactt tctttgcaca gcctctgcaa
    29281 cgactctagg taccccaact tcgacaatct catccacact ggcttccttg attttggtca
    29341 aagacttgaa atgcttcata agattctgct tgcgtttagg tcccagaccg tcaatcccat
    29401 ccaattgaga tgagaaagaa tttttggagc gcagttggcg gtggaaagtg atagcaaagc
    29461 ggtgcacctc atcttggatg cgttggagga ggaaaaattc ctgagaattg cgagacaagt
    29521 ccaccacctc aagcggatct ccaaagagca attcatgggt ttggtgctta tcattctttt
    29581 gcagcccagc aattggaata tccaagccca gttcctcttg gatgacttgc ttagcaatat
    29641 tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg aggagtcaaa gcctcacgct
    29701 gtactcgacc atagcgtctg cgaatgactt ctctcatact agcatagtcg tccggcccaa
    29761 caacggtttt tatcttgtac ttacggtaat cttttttact tggcctgccg ttaacaaaga
    29821 ccaccatggc tgaaacagga ctggtcccca tgatgttgga gttatcgaag gactcgatgc
    29881 gaactggagt cggaatttgg agcaaacgtc ctagattttc aatagctcct tgggtctttt
    29941 cgactgattt ttctagcaga ttgaacttct gctctagact aacacgagca ttttttatgg
    30001 ctagattgac cagctgtttt ttctctccac gttggggttt gagaatcttg gtatccacca
    30061 aagccttgac agcttcttcg tcaatatcct gcggaatcag tacctcattg ggaactaggt
    30121 gagatttttc ttgatagaat tgtcccacat aggtcaagaa atcctcatct ggatcattga
    30181 agtaggggaa gagattgaca tcgcgctcga tgagcttgcc ctgacgaaca aagaaaacct
    30241 gcacacacat ccagccctta tccacatagt agccaaagac atcgcgattt tggagatcct
    30301 tagccatgac ccgttgcttg gttcgaagtg ttccaatggc ctgaatcagg tcacggtatt
    30361 ccgctgcccg ttcaaactcc atactttgtg ctgttactgc cattttactc ttgagatcat
    30421 cgatgatttt gtcatcctga cctttcagaa aatcagacac ctcctgggcc atggacttga
    30481 aataggcctc gtcattctta cagatggtgt gggccataca ttggccgata tggtagtaaa
    30541 aacagacctt agagggcggg ttggtacatt ttcgaaaagg gaaaatccta tctagaagtc
    30601 gcttgatttc attggctgcc cccacatctg gataagggcc aaaataaaga ccaccgtcct
    30661 ttttgacctg acgagtaatg ataagccgtg gatagtgctc attggtgatt ttgataaaag
    30721 gataagactt gtcatccttg agcatgatat tgtacttggg cttattttcc ttgatcaggt
    30781 tgatttccag cagaagcgcc tcaatattag actccgtaac aataaattca aaatccacaa
    30841 tttcagacac caaggcctct gttttggtat catgacttcc acggaaataa gacctcacgc
    30901 gattacgcag atttttagcc tttcctacat agataatggt gccgttttta tccttgtaaa
    30961 tgtagcaacc agggctggtc ggcaagagct ctagttttgg tttaatcaag ttgttcatag
    31021 ttccattata gcaaaaaagt agggaaagat agtaccctac tcattagtct catatatttt
    31081 tcggaggttt gcaacatcct cttcctggat accataaaag gaacctgctg gttgcatgac
    31141 agacttctca tctgtatggt ccaagccaat cgcatgacct aactcatgtt ctgccgtatg
    31201 gacaaggcgt tcataggaat agccatagta tggattggac aaataataat gattcaaccg
    31261 caccgttacg gacaagaatt gccctgttaa gagattagtt tgactttccg cctctcctgc
    31321 cacaggagtg cctccgtcgt tcatctccgt agccgtaata tccgccttac tagactcagt
    31381 cacgagttca aagttaaaag caccagtttg attccagttc tggattgctt ctaaataagc
    31441 ctcttgaaag cgtgaatcca tctgcggatc caggtaaata cgagcagagg cctgtggcca
    31501 ccttccttca gaatgctggt gactatctgt ctggcttaac ttaggcagtt gccctgtttt
    31561 ctcccattgg tcaatacttt gttgaccaat ttttactgac cgttctgctt gctttagcgc
    31621 tccttgaaaa tccccgttca gataccagag aagtccgaaa gcaagcacac ataagagcac
    31681 aactatccaa accagacgcc aaaacaaacg ccacacaaaa gaaaagaaag cccctatcaa
    31741 acgaaaaagc cagcgcatgt ctctccacct ttctagcaaa taaaaattat tttactaaaa
    31801 gaagctaaaa gaaatctaaa tactgacttt ttcatcttaa cgtcctacta tttttttgag
    31861 taactggata gctttgtatt ttaaaggaga tggatggtaa cggaaagtac ctgctttgcg
    31921 tacaatatag ccattaaaat tctgtttaaa acgcaaaaca ccatcacttc catcaaaaat
    31981 cccttgaatg cctaggaagt tgtatttagg tattccacgt tttatgcttt ccaacataac
    32041 atatttttga agcagtgcag gggcatagaa cttattaaac tcagtgtagg aaccactaaa
    32101 gagataagtc gtttcctgag gcatataaac aaataaactc ccagctaaaa caatatcttc
    32161 ttctccatat ttttcaatca agtctcgcgc ttctgctttt cgaacttcaa acgtttcaaa
    32221 ttgactagaa tattctctca gttgattttg ttttttctca gaatgaggat ttttactcaa
    32281 atcaagtcgc aacttgtcca agttttcttc tagtttattt tgttcacctt gcaatttgct
    32341 catatagtcc gaaaaattta agcttgctat gagaaactcc gcttgttctc caaaagtatc
    32401 ataaaaatgc tcataatatt ctaaactttt atcactatat tctctacgtt cagaggtttc
    32461 ttttgttata ttcttaaaaa tcgatagttc ttcacgtttt aactttttca atcgaatgcc
    32521 aaaggtttca gcctttttca ccaagggttt accctttttg ctaaaacttt taagcaaact
    32581 cttttcagtt aattcagtta aatctttata gtataaccaa tctggttctc cacctgggta
    32641 acctgttgtt aagccatcaa attgataacc taaatcagtc aaaccttgaa taatactttt
    32701 tttctcagca tctattggat taccttggct atcaaaagtt tgataagttt cataaggttt
    32761 tacaagcaac tctaatacac cattttgctt ggcatattct tttaactctg cataaaaaac
    32821 tggaagagca tcttgttggg tataaatcgg ccccgaattg agttccatat gcagaccacc
    32881 cagcatgggc aagctataaa ccagagctgc aacttgaatt tctccttctt gtttcaaagc
    32941 aagataaaca attcgagccc ctcttttttc tagcaaatcc cccatctgga cagattgcat
    33001 aaaggaacga gaagaaacct gatcagaata agtctgaaac tcttctttcg tgagtgttgt
    33061 tagtgccata tacttacttt ctatgttttt ttcttaatgt tttacggaaa tcaagagcaa
    33121 gtcttaacag aggatagaga ggatgagtgg gcattgtaaa ttcacccaag tattcttcaa
    33181 tcgttggatt aaatttttcc ttaaaatgat aaagtccacc attgagagag ttttcaacac
    33241 cacctaaatt ttgccagacc atacctcgct caaaggcata gcgagccgtt tcataccatg
    33301 ttaaaattgg tgcattgtaa cgtttaaaat catcatccat accagcatat atattgacag
    33361 aggtagtacc aaattccaaa ctcaaagtag ccgctaaagg aactctcgct tgacctacat
    33421 ctatatattc ctgcaagaag gtcaattcct ctaacaaacg ttctttttcc ttcttctgcg
    33481 cttctacttt tgaagttcga gtcgactcag taaaggtctc ttccaaggct ctatttttcg
    33541 ctaactgttc ttctaattct tgcgaacgtt tagaaacatc caaggtggcc aaggtgatat
    33601 aggccttgtc cttaaaatta tctaacaatt ttttataata ggcttcattc ctcaaatgaa
    33661 tctcttttcg cttctcagtt tttttcatca actccgaaaa tgaatctaat agttccagtc
    33721 caccatattg aatctcaagc cctttgtttc gtgctgttcg aatagcctgt tttgttgact
    33781 tggaaagttt atcttcttca aaattttcct tgtatatttt cgcctgaata cgaggttgaa
    33841 tggtgtctcc catttcctcc gtttttcctg accaccttac tcccatttgt tgcaaactat
    33901 caataatagc cagattttca ggaaattctg tcttttcctg attgattaaa ctttgagata
    33961 ggcaaatact tgggtcaaaa gtcacaaaaa ccgctctctt actgcgagca taggacttaa
    34021 tagactgaat ggcaaaattc aagagttctt tatccccata atccaatata ggtcctcttg
    34081 ggatgtaaaa cattttatag cctagcggaa gagttctaat caaaatacta gctgtcgcca
    34141 gtaatttttc ttccctgtaa acaccaaact tctcatgttg ccaattagac ttaacttcct
    34201 cccaagcact actttgtaat acattggcta attcatgttc tttgacaaac tgatcatatt
    34261 ctaatgtggg aatgccaatt tgataacggt acatttccta ctctctttcc tccagtattt
    34321 tattactatt ctactacttt cgtttgaaaa gtctagtgaa aacatatttt attttagttc
    34381 tactccccct atgctgaagt tcaaactaag tcagtctctc ttctaatttg aaatcaattg
    34441 gtagggttgt taaaaaaact tccaattgtt tttcccagta gtaccactcg tgagttccag
    34501 cactatggct ataggtcaca tcaaaaccta gttttttgag atttttcact gcgagattat
    34561 tggcttcgta caagaaatcc tgttcgccac accacgccca aagtttggtc tttttatccg
    34621 attttttagc cagactttca agagaatagg gactagttgt ccagtctcta atctctccaa
    34681 aaacacctct ccagtaggct ggacttccca gattttgact ttcaggagaa aagttttgaa
    34741 agctgagggc acctgaaaaa ctagctgcat gagaaaaacg atttgtcgta agagccagtt
    34801 tgaagcagcc gtagcctccc atagaaagac cagcgataaa ggtcttttca cgcttgctag
    34861 tcatattagg gaagaagcgt ttcagaacct gtggcaattc ctctgctaga gccgtgtagt
    34921 agtcaaaacc atactgggta tcggtgtacc aaccattgct ggtattgggc ataacaacga
    34981 tgagattagt tcctcgaagc aagcgttcta cattggtccg cttaagccaa ctattatgat
    35041 ttccagacat cccgtgcaaa aggtacaaga cgggaatatc ttcacactct ggttcttcca
    35101 ctcgattggc atcagggtag aggacattca ccccccactc catatccaat acttgtgagt
    35161 aatactcgat tttcattact gccatgattt tctccttcta tttttctata agaaaaagcc
    35221 gaaactcgac tttctctctg tttatttcaa cgattatttt gcttccatga ctactggtaa
    35281 aatagctgga cgacgcttgg tttggtcaaa gagatacttg gtcaaattat ctcgaacctt
    35341 ccctttaaga tctgcccagt caaagtcatc tccttgaaga taatcttcta ccgtttggtt
    35401 aatcaattct gaactttcac ggagaatatc gcgactcttc ttgagataaa caaatccacg
    35461 cgtgtgaaca cgagccctag ccacaatttt cttctcacga cggttgactg taatagccac
    35521 gatgaaaatt ccatcctctg acaagacctt acggtcacga agaacaacat ttccaacatc
    35581 accaatggca ttcccatcaa tcaagatatc tcctgctgaa accgatccag ctggaacaaa
    35641 gtctccattc tcgtaagcca tggtcgtccc ctttttagga atgaaaatgc gttctggcaa
    35701 catcccaact gccatggcag ccttagcgtg agcatccaac tcacgatact ccccttggac
    35761 agggaagagg tacttaggtt gcaaaagatt gatcatcagc tgcaaatcac gcacatttcc
    35821 gtgccctgat acatgtaaac tttgggtaat caatttgaca accccacctg cctgataaat
    35881 catattttcc acacgcgcaa caaaggcttc tttagcaata gacggagccg tagcaatata
    35941 gaccaggtcc ccatccttga tttctacata acgatggcga ccaatcgaca tcttacgaag
    36001 tccattgata ggttcaccca tacgacctgt ctcaagaata atcaactcat ggtcttcaaa
    36061 gcgagacata tctttaggct taatcaagag aatttcgttg gctaaagaca acttcttaag
    36121 acgaatcgct gtgcggacga tattttcaat atcaaatcct gtcaagacga tacgtcgacc
    36181 tgttttatcc gcagcgtcaa aaatctgctg aatacgagaa agattactgg aaacagctgc
    36241 aacgatgata cgaccttccc agtcagcaat agtttgggta atttcatccc taacttcact
    36301 ttcactagcc acctgaatat tgctgtctgc attggccgaa tcactgagga gagccaggac
    36361 gccgtcacga ccaatctctg ccaaacgagc aaaatcagtt gcataagatt cactagccgt
    36421 ttggtcaaat ttgaagtcac ctgtataaac gatgcttcct tccgatgtct tcaagacaat
    36481 tcccagactc tctggaacgg agtaagtcgt agggaagaag gaaaccactg tcccaccaaa
    36541 atcaatctcc gtattctcat caatgacatg gaaatcatta aatttcttaa cggcatcatt
    36601 tcctttgaca aagagctttg ccaactcaat ggtcaactca gacccaaata caggaacttt
    36661 agcctctgcc aagagataag gtagagcacc aatggcatcc gcatgcccgt gggtcaagaa
    36721 aaccccagca atacggtcgc tattttcaaa aaggtaatcc atgtttggaa tcaccacatc
    36781 gacccctaat tgttcatttt caggatattt taaccctaca ttcaaaacaa aaatggactc
    36841 tccaatttca gcaatgtaca tattttttcc attctcacgc acaccaccaa gtgttgttaa
    36901 actgatatta ctcatttttc ctccaaaatc ttagtttatc ttgattatag ggcaattcta
    36961 ccctcttatt ctaaaagttc tgatactttc agccgaatct tttcctacca ttataccatt
    37021 tttttgatga ttttcaaaat gaaggtctgt tttcaaaaaa gagttgattt cccaactctt
    37081 tcctaacttc tactcttttt ccatcaaaaa atcataaatt tcttgcaccg tacccagcgc
    37141 catcatttct tggtctttaa cggtttgttt gagattttgg taaatttgac tttctcctat
    37201 ctcccgcttt ggcgcctctt tattgactgt catcacacca tcttttatcg tcacaaagcc
    37261 tagttcttca aatacttgaa tcatcttgac cagcaagatt tgttgaatat taagatatgc
    37321 agccaaatct ttcagcttgt agcgaatatc aaactctggg aactggtaaa tagtcttgta
    37381 caatttagca aactgatctc tagtcccata acctgtcaga taataggtct tgtcaatatc
    37441 atttttgaaa tagacagcag agaaatgctg ttcctgaaaa atggtcttca gctgagtaat
    37501 atcctctgga atgtttttta cgacaacagc ttcactagcc gcaagatttg gcagttctcc
    37561 aggaaaatcc aagactggaa caccttctgg caagactgca ttttttccac gaatgttaaa
    37621 aagttgaaca ccttccactc gcgcatccac catcatcaac tggagggcag tttggccatt
    37681 ccattggttg acagacaatt taaccgctaa ctctagattc ttggtttgag aaaactctgt
    37741 cgcccatctg ccttgaccaa aggctaccac ttcaaaactc gcctcaccct tggaaatttt
    37801 cagctttaga tgggcattac ctgcccccat agtacgagca ctttcgacct gaaaattctt
    37861 gatataaaaa ataggtttct gattatccat tccaaaagga gctaaacgtt caaaactttt
    37921 gaccgtttcc aagctaagtg cctccaaatc caactcttca tctaggttta acttattctt
    37981 gccaccagca tctgcacctt tttcacgaac ataatcttcc aaaacctgag ataaatctga
    38041 gagttgctca acttccagcg tcatacccgc tgcacctgca tgacctccaa aggcgatgaa
    38101 gaggtctcga tggggatcca gagcttcaaa aatatcgacc gcttccacac tacgagcact
    38161 gcccttggca cgaccgtctt ctatattaag aacaatgact gtctgtccca attcttccaa
    38221 taaacgacca gccacgattc ctagaacccc aggattccag ccttccttgg ccaagacctg
    38281 aaccttcttc tcaggatcca ccatggtctt ggcttcttca tagatagact gaacgatttc
    38341 cttgcgctct tcgtttttct ggtgaatcat aagggcaatc tcatgcgctt cctcatcatc
    38401 aaatccagtc aacaaatcaa tggcaggatt gggatcatcc aagcgaccca aggcattcaa
    38461 acgaggagca atctggaaac caaccgtttc ttctgttact tcgttggcag caatcccagc
    38521 catgtccagc atttcttgca gaccaatgcg ctgggtatga cccaacattt ccagaccata
    38581 ttgaactaag atacgatttt catccgtcag actcaccata tctgcaatag ttccaatagc
    38641 gaccaaatca agcaattcca cttgcacttc ttctaacagg gcacaagcca acttgaaagc
    38701 aactccacaa ccagccaaat atttaaaagg ataatccgca tctggatgtt caggatggac
    38761 aatagcataa gcatctggca gggtttcagg catggaatga tggtctgtca caatgacatc
    38821 tactcccata gactgagcca atgcaatagc ctcatgacca gcaaccccat tgtccaccgt
    38881 cacaatcaag gaaattcctt cttgctcgat aaagtattta taaacactag cattagggcc
    38941 atagccatcg gtaaaacgat ttggcaggta aactcggcac tcagcaccaa gttgttccaa
    39001 actttccttc acaatagaag ccgaagtcat gccatccgca tcatagtctc cataaacgag
    39061 aatattttcc ccttcttcaa tagcctgacg aatccgctcc actgccttgt ccatatcatg
    39121 gagcagataa gcatcatgta agtcctccaa ggaaggttct aaaaacttct tcagactttc
    39181 ttggtcctga atccctctct caaacaataa ccgagccacc tcaggaccca gtccagcctt
    39241 cttggctatc tttgtaaaat ccgcatcttc tacctgcagg gcaaactgcc attcataagt
    39301 aggtgttatc aaaaagacat ccactctttc taagaattct attgcttcat tataacatga
    39361 tttagacgtt ttctctatcc agattgcttt tttataacat tttatagtat attgaaacta
    39421 gaatagtaca cttctacttc taaaatattg ttagaaatcg atttgactgt cccgatcgat
    39481 ttttcctgtt cttatttcac tatagtgaat tttttcagat atgatttgac aagaacattc
    39541 ttttattgca gaatcgtgtt ataaaatcta acataaagga gttctctcat ggttttagta
    39601 gaatttaaaa acgtcgaaaa atattacgga gactaccacg cactccgcaa catcaatctc
    39661 cgttttgaaa aaggacaagt tgttgtcctg cttggacctt ctggctctgg gaagtccact
    39721 cttatccgta cgatcaatgg tttagaggct gttgacaaag gaagtctcct agtcaatggg
    39781 caccaagttg ctggtgccag ccagaaagat ttggtacctc ttcgcaagga agtcggcatg
    39841 gtttttcaac attttaacct ttatccacac aaaacagtgt tagaaaacgt gacacttgcg
    39901 cccattaaag ttctaggaat tgataaaaaa gaagctgaaa aaaccgccaa aaaatatctg
    39961 gaatttgtaa atatgtggga caagaaagat tcctatcccg ccatgctatc tggtggacaa
    40021 aaacagcgga tcgccatcgc tcgtggtctt gctatgcatc cggaactcct cctctttgat
    40081 gaaccaacat ctgctcttga tcctgagact atcggagatg ttctagcagt tatgcagaaa
    40141 ctggcgcgtg ataggatgaa catgatcatc gttacccacg aaatgggctt tgctcgagag
    40201 gttgcggacc gcattatctt tatggccgac ggagaagttt tagtagatac gacagatgtc
    40261 gataactttt ttgacaatcc aagcgaacct cgtgcccaac aattcctcag caaaattatc
    40321 aaccacgaaa gtgacaaagt caaataagga ggcgcctatg aaaaaaaatt ctttttatca
    40381 gcattattga ttagcctttt cggccttgct gctgccaaac cagtccaggc tgatacaagt
    40441 atcgcagaca ttcaaaaaag aggcgaactg gttgtcggtg tcaaacaaga cgttcccaat
    40501 tttggttaca aagatcccaa gaccggtact tattctggta tcgaaaccga cttggccaag
    40561 atggtagctg atgaactcaa ggtcaagatt cgctatgtgc cggttacagc acaaacccgc
    40621 ggcccccttc tagacaatga acaggtcgat atggatatcg cgacctttac catcacggac
    40681 gaacgcaaaa aactctacaa ctttaccagt ccctactaca cagacgcttc tggatttttg
    40741 gtcaataaat ctgccaaaat caaaaagatt gaggacctaa acggcaaaac catcggagtc
    40801 gcccaaggtt ctatcaccca acgcctaatt actgaactgg gtaaaaagaa aggtctgaag
    40861 tttaaattcg tcgaacttgg ttcctaccca gaattgatta cttccctgca cgctcatcgt
    40921 atcgatgcct tttccgttga ccgctctatt ctatctggct acactaataa acggacagca
    40981 ctactagatg atagtttcaa gccatctgac tacggtattg ttaccaagaa atcaaataca
    41041 gagctcaacg actatcttga taacttggtt actaaatgga gcaaggatgg tagtttgcag
    41101 aaactttatg accgttacaa gctcaaacca tctagtcata ccgcagatta aggaggatac
    41161 cctatgacag atttatcatc ttggacagcc tattttcagg attttggaca atttttcaat
    41221 ggtttcctct ttactcttgc cctagcgatt ggatccttta tcctcgccat ggtcttagga
    41281 atcttctttg gtgccatgtc aaccagtaaa cgtccaattt tacgcatttt agctcgcatc
    41341 tttgtggaat tttaccaaaa tactcctctc ttggtgcagt ttgttattgt tttttatggc
    41401 ctacctctta tcagtgacca tatcatcatg attccaattt attggacagc cgttctctgc
    41461 gtgggactct atcacggcgc ttatatcgct gaggttattc gttcagggat tcagtctatt
    41521 cctagtggtc agatggaggc cgccttgtcg caaggtttta cctatatcag tgccatgcgc
    41581 ttgattacct tgcctcaggc cttccgcatc attctccctc cattgaccaa ccaaattgtt
    41641 aacctcatca agaacacctc tactgtagct atcatctctg gagtagactt gatgtttgtg
    41701 actaagtctt ggtcggctct caacggaaac tatatcccag cctttttagg tgctactctt
    41761 ctctactttg ccctatgctt ccctgttgcc cagtttggtc gcaagatgga gcaagccaac
    41821 aaaaaagcct attcacttta ggaggttact atggaatcta ttttagaagt tttaacccca
    41881 gataacctag tctttatctt taaaggattt ggcttgaccc tctatatttc tctgattgcc
    41941 atcatcctct ctactatcat cggtacggtg ctagctgtca tgagaaatgg caaaaatcct
    42001 gtcttgcgaa tcatctccag catttatatc gaatttgtgc gcaacgttcc caaccttctc
    42061 tggattttta ctatcttttt ggtgttcaaa atgaaatcca caccagcagg tattacagcc
    42121 tttactctct ttacatcagc agccttggct gagattattc gaggcggtct caatgccgta
    42181 gacaagggac aatacgaagc aggaatgtca caaggcttca cctcagccca aatcctctac
    42241 tacatcattc tcccacaagc catccgcaaa atgctaccag ccatcatttc tcagtttgtt
    42301 accgtgatta aggataccag cctcctctac tctgttatcg ccctacaaga actctttgga
    42361 gccagccaaa ttctcatggg ccgttatttc gaaccagagc aggtcttcag tctttgcatc
    42421 ctgattgccc tcatctactt cagctttaac ctagcaattt ctagcctgtc tcatatgcta
    42481 gccaaacgtt ggcaacaagc tgcagaataa tactcttcga aaatctcttc aaaccacgtt
    42541 agctctatct gcaacctcaa aacagtgttt tgagcaactt gcggctagct tcctagtttg
    42601 ctctttgatt ttcattgagt ataaacagcc actctccagt tcaattggag agttttttga
    42661 tgagagtaga tatttataga cctcaatttg acaccataca ttttctatga taaaatgtaa
    42721 caaatttatt tacaacaaat cgaaatctaa atgaaatgga attttctatg aaatcagtca
    42781 aaggactact ctttatcata gctagtttta tcttgactct tttgacttgg atgaacactt
    42841 ctccccaatt catgattcca ggactagctt taacaagcct atctctgact tttatcctag
    42901 ccactcgtct cccactacta gaaagctggt ttcacagttt ggagaaggtc tacaccgtcc
    42961 acaaattcac agcctttctc tcaatcatcc tactaatctt tcataacttt agtatgggcg
    43021 gtttgtgggg ctctcgctta gctgctcaat ttggcaatct tgccatctat atctttgcca
    43081 gcatcatcct tgtcgcctat ttaggcaaat acatccaata cgaagcttgg cgatggattc
    43141 accgcctggt ttacctagcc tatattttag gactctttca catctacatg ataatgggca
    43201 atcgtctcct tacatttaat cttctaagtt ttcttgttgg tagctatgcc cttttaggct
    43261 tactagctgg tttttatatc atttttctat atcaaaagat ttccttcccc tatctaggga
    43321 aaattaccca tctcaaacgc ttaaatcacg atactagaga aattcaaatc catcttagca
    43381 gacctttcaa ctatcaatca ggacaatttg cctttctaaa gattttccaa gaaggctttg
    43441 aaagtgctcc gcatcccttt tctatctcag gaggtcatgg tcaaactctt tactttactg
    43501 ttaaaaattc aggcgaccat accaagaata tctatgataa tcttcaagcc ggcagcaaag
    43561 taaccctaga cagagcttac ggacacatga tcatagaaga aggacgagaa aatcaggttt
    43621 ggattgctgg aggtattggg atcaccccct tcatctctta catccgtgaa catcctattt
    43681 tagataaaca ggttcacttc tactatagct tccgtggaga tgaaaatgca gtctacctag
    43741 atttactccg taactatgct cagaaaaatc ctaattttga actccatcta atcgacagta
    43801 caaaagacgg ctatcttaat tttgaacaaa aagaagtgcc cgaacatgca accgtctata
    43861 tgtgtggtcc tatttctatg atgaaggcac ttgccaaaca gattaagaaa caaaatccaa
    43921 aaacagagct tatttacgaa ggattcaagt tcaaataagt aatcatactc tcctgggatt
    43981 tcccaggaga gttttttata gccaaatgaa ataagacagg aacgatggaa ttttggcatt
    44041 caaatcaatt gataagaatg ttttatagtg gagtgaaata ggatacgaac aaattgatta
    44101 ggaaaatcaa atgaatttat agaaatcttt tagcagttat gttgtcctat tctagtttca
    44161 aaacgctata gaagcagcat tgtgctagtc tagattcagt ttactatact aaaacgagta
    44221 gcttgaaatc aaaaaaccca ccctcacagg caggttttat ctgtattatt cagctagatt
    44281 atgctttacc ttctgaaccg aatacgtcga tacgttcttc aaccgatgct tggatagctt
    44341 ttacaccgtc agccaagaat ttacgtgggt cgaagagttt tttcttgtcg tattctgctt
    44401 cgtttgcttc gtagtcacga gcaaatttac gagttgcgtt agcgaatgcg atttggcatt
    44461 ctgtgttaac gttaactttg gcaacaccaa gtttgatagc tgcttggatt tgctcatcag
    44521 gaatacctga tccaccgtgc aatacgattg ggaatcctgg aagagcttct gtcaattttt
    44581 gcaagtggtc aaggtctaga ccttcccagt ttactgggta agggccgtgg atgttaccga
    44641 taccagctgc caagaagtcg ataccagttt caaccattgc tttagcgtct tcgattggag
    44701 ccaattcacc tttaccgatg attccgtctt cttcaccacc gatagtacca acttcagctt
    44761 ctactgagat acctttagcg tgtgcttttt caacaacttc tttagccaat ttaaggtttt
    44821 cttcaactgg aaggtgtgaa ccgtcaaaca tgattgaagt ataaccaact tcgatacact
    44881 caagtgcatc ttcgtagtga ccgtggtcaa ggtggatagc tactggtaca gtgataccca
    44941 ttgattcaac aaggttagcg atcaagttgc gagcaacttt gtaaccaccc atgtatttag
    45001 cagcacccat tgaagtttgg atcaaaactg gagctttttt agcttctgct gcgcgcaaga
    45061 tagcttgagt ccactcaagg ttgtttgtgt taaatccacc aactgcataa ccgttgtcac
    45121 gggctgcttg gacaaatttt tctgctgaaa cgattgccat tttatcaggc ctcctgtata
    45181 tttttatggg tcatcccatt tacattgttc attttatcac tttttgccaa aaaaatctag
    45241 tttttcccgc agtttcgatt gattttcttc taactccatc tatgtaaacc ctttctccct
    45301 agtcttggac gacttttgga aaatctataa agaaggttaa acgattctcc tccatctcga
    45361 aacgataagc taatttttca tgttctaata gactcttaac cacaaagagc cccataccag
    45421 accccttgac cttgcgacta gcattgtcag aaaaagactg ggctagtttt tcttgttcct
    45481 ctgagctaca gctattttcg ataaaaagtt ctccttctct ttctccaatt cgaactaagc
    45541 cacctggaac agagtgctta atggcattgc tgatgagatt agaaagaatc aacttcataa
    45601 ctgatgggtt tagataagcc tgctgatggg tcaaactatt gtctatctgg agctctcttt
    45661 cctttgctag caaggcataa tctttgacca gattttgcgt catctggagg aggtcaattg
    45721 tttccctatc atctcgcaat tcctgcacag aagagaggga aagtatctgc agaacatggt
    45781 gattgagttc atccacaatc cccaaggcaa ctcccagata ctggtctcta tccttataac
    45841 gaccgatatt ctctctcata ttttcgatta ggattttcaa actagccagc ggtgttttca
    45901 attcatgaga agctcctcgt aggaattcga ccttcatctt ctccagctgg agaatggctt
    45961 cattcttttc atgcaagtcc gcaataacag tcaagagatg ctggtagagg ctattgattt
    46021 gttccttgag attacctatc tcatccttag aatccacgcg caatcgcact tgggaatcca
    46081 ggtccatcat ccgacgggtc acccgcttga tttccaaaat cggtgcaaca atagtccgag
    46141 cgtagatgta ggccaccaag agggaaatca gaaaggaggc cagcaaggta tagggaagaa
    46201 actggagact gatttgctcc gcttcctttt gtaaatccat ggaagctaga aactggagaa
    46261 tcatagtacc accgtcttgc gttttcacct cgcgctcctc aataaagaga gaggttgtct
    46321 ggcggtctgt gtccagagga agactgtcct tgacttctaa cttgtcctcg gtcatctcac
    46381 ctttgacggt ccccttgata tcactagtct gggaatacaa gtctaacact tgctcgatac
    46441 tctgcctatc tttcccttct agggactggg caatggctgt tgccttttga ccaatggttt
    46501 cctgacgatg actcagataa gtcgaaggaa aaagaaaata aatagctaaa tgaaggcaga
    46561 taaccagaac actaaatatc gagaaggtat agataaatat ctttgcaaat aaacctgttc
    46621 gtttcatttt cgctccaatt tataaccaac attgcgcaca gtgaggatac aatccaagtc
    46681 tagctttttc cgcaattcct tgatataaac atcaataaca cggtcaaagg gaacctcatc
    46741 tgtcgctttc cagacggcat cgataatctg agatcgagtc aaggcccggc cttcattttt
    46801 cactagatag tccagaattt ccaactcttt ggcattgata ggcacttctt gacctgcgag
    46861 gcttgcactg tagctttcaa agtccacctt ggtatccttg taagaaaaga ttcgtcctgt
    46921 atcgtagtag cgcttgaaaa tcgcgtccac cctcactttt aaaagggaga gggagaaagg
    46981 tttttccaga tagccatctg ccaaagaggc aaaggcactc atcttgtatt cctcatcttg
    47041 aaaagctgtc aacatcaaga caggaacctg actggtttta cgaatctcag ctaggacttc
    47101 taagccgttg agcttgggca tctggatatc cagtaaaacc agggccacct catagctaga
    47161 aaattgctcc agagcttcct gaccgtccgc tgcctcaata gtttcatagc cacaatccgt
    47221 caaataatca ctgaccccct cacggatcat ctcttcatct tctacaatta aaattttcat
    47281 actttaactg ctctctattt tttatttttc ttagaataaa tacctaccct attttctatt
    47341 atagtctctt gctggccttt tgtctgcaag caactgacca ctagataaaa cgttgtgaaa
    47401 ttcctttctc ataaattcca taactttagt atattatatt taagcactaa agtacaaaga
    47461 aagcaactga aagcaatgat tttcaccact gctttcggat ttattttgaa ttgttaaata
    47521 gccattccta tccactattc ttgaatagaa acacaagatg caatctttat tctagactca
    47581 ttttttcaaa tttattcacc atccagcaag agctcttttg gttgttttct aaggagattg
    47641 cttgaagcaa gcgccataac gagaaccact agaaccaagg caaggacaaa aatgatgata
    47701 aagtctgatg tctgaatgga aatgtctagg ctcgacaagg tcttgctaaa gccatctact
    47761 tctgcaccac caccaaggtt agaggcttga gccgccttac tagcctgttt ggcaacacct
    47821 gaagtcacat tggcaaggac agtgtttcca attgcacggg cagtgtaatt agctaggaag
    47881 taagcagaaa ctagagcagg gatagcaatc aagatagatt cggtgatgaa ttgacccaag
    47941 atacttgcct gcttgaggcc gatagagagg agaattccca cttccttgcg acgggcgttg
    48001 atccaaaggc tgagcaagag ggcaaggagg agaactgaga agctcaagct accccagaag
    48061 aggaggttgg ccatcttgta cataccagag atagattgct caagagctgg gtagttagag
    48121 gagctcttga cgagtgtgta gctcttccag ttgataccac tgatgccatt caactctttc
    48181 ataacatcat ccaagttctt gtctgctgtt acaaagaagg ttgcgtcccc ataaatggct
    48241 gtgtcttctg tgtatccata aagttttgca gcagtgtgaa tgtctgtaat agctgtgttt
    48301 tcgtaaagtt cttgtgagta ggttactgct gacttattat gaccatcaaa gagtcccttg
    48361 attgtcactt caactgtttc cttggctcct ttttcattat ctgcatcgta gatattagag
    48421 tccagtttaa ccttgtcccc tactttccag ccgtgtttgg ctgccaagtc cttgtgcaag
    48481 aggattttat ccttgtcgtc gttggttaag tgctctcctt cgactagttt ataagaacca
    48541 gagacaaact tgtcttcttt agaggagtca ttgacacctg taatcatcaa gctacttcca
    48601 aaacgcttgg cacgatcagc agtgagattc ttcttggttt ctggcgtttc aatcaggtca
    48661 tatccagtca aatctccgat agcgttgata cgtttgacat aagactcaat ggccttgttt
    48721 tcggtgattt ttttgatgtc ttcacccttg atattcccag caccacgagg cgttccttgg
    48781 ttgacgcgac gattgatttg catggagaag ctattggtga tatttttaaa ggtctcctga
    48841 gaagccttgg cagtagctcc cttgattgac aagccgacca aactcaagct cgccatgagg
    48901 agaataatca ggaagatgac aatcgatttg aaaaacttcc ttgtaacata ggcaaatgcg
    48961 ttgtgtaaca tagattccct ttctagattt tgttttaatc attctattaa aataagctca
    49021 aattatttac tagtattgcg cgtttcagtc agtttcttat cctttaattc aagtgtaata
    49081 tctgacgctt gtgccacttc tttactgtga gttacgacaa tcacacattt acctgttttc
    49141 tgggcaagtg atttgagtag ttcgacaata tctccagcag ttttaggatc cagatttcct
    49201 gttggctcat cagctagaat aactggagct tctgagacca aactgcgagc aatggcaaca
    49261 cgttgctgtt gaccacctga taactggaga acattccgct tgatctggct ttcatccaaa
    49321 ccaagctcaa gaagtgtatt cttgcttgcc tttttgttga ccaatcggat attttccagc
    49381 ggagaaagat aatctatcaa gttataattt tgaaagacca gggaaatatg gtgcatgcga
    49441 tggtaagaat agcccttctt acgaatatcc tctccttgaa aaaggataga accttcaaca
    49501 ggactatcta gaccagcaag tagggacaag agtgtggatt ttcctgctcc tgactcccca
    49561 ataatactgt aaaattttcc gggttcaaaa ttataattga tctgatatag gactgcttca
    49621 gcagtattct tataacggta ggtaacatct tgtaattgta ataaagtcat gatttctcct
    49681 tcttaactaa tagatgataa aatttctttc ggtgattttc taaataagaa taggaaacaa
    49741 agggctacag ataagcaact aagcagaact agaaaaacat aggattctgc aaaagataag
    49801 atgctagttg ataaactgct tgctttggct agtgtatctt gtaagcttgc ctgatctcca
    49861 cttgctagta gagtttggag taggtaagtt gtgattgcgt ttcctgcaac aaatgctgga
    49921 agcaaagctc caagagatac caaaactacc tctaaacaga attgtaggaa gatcgagctc
    49981 ttgccttttc caagtgcaag taaaatcccc acttcataga cccgttctct caaccagaga
    50041 gacaaaacca gaattaaggc tccagctcct gctatcaaca tcccataaag gaagatggtc
    50101 aggaaggttt ggaaagttgc aactgagtct ttgatttgtt caaaagcctt gttttccttt
    50161 tcgacttggt agccttgatt ttccaaggcc aagttttcta cctgcttcat gagtccgtcc
    50221 atttccttag gattttctac atagaagcgt gctgcactga cttgagcttc actattgccc
    50281 aaaagggttt ggctactttc atagtctgta aagacttgat tttcactgaa gtcagaagac
    50341 aagcctgtga atttctcttg ttttttacca gaaaagatgc cgataatctc aaactctact
    50401 gtttgtcctt ttccagattc agactgacca gcatccaagc caatcttgtc atgaagcgaa
    50461 agaccgttct tcttagccaa ttcttcgtgg ataaggattt tcttggaatc ccctttttga
    50521 aggtgtcgcc cttcttttag attgaaagcc gaactggtaa aggttacatc cttggatgaa
    50581 tcctcaagag ccgttaagct aaccaagtta ttgtctgcag ctgataaatc atcacgctcc
    50641 acgctctgct cgccagtcac tgcttccttg tcttttagtt ttgcgaccgt ctcaagttca
    50701 ggagagacat tttccagccc cttaatcttg cttacagatg ctaggtctga caacttgaat
    50761 gtctgaccat tctctatctt cttaatagaa aaagatgtat tgagtgattt ataaagattg
    50821 ctttctactg ttttgttgga cttcatcaga gtcaaacagg ctgaaattcc ggccaataag
    50881 accaataaaa tcagaaataa aataaaactt ctcagtcgct ttctgctgac ataagcccaa
    50941 gatctttgga ttggattcat ttgtcacctc catatttgta agactattat aaaacccaaa
    51001 tatgaaatgt ttatgaaata cgaaaaaaaa atatcgagta ggggataatc tctagcccct
    51061 ctcacaccac catacgtgcc gttcggcata cggcggttca a
//
LOCUS       DAVLHM010000009        48823 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLHM010000009 DAVLHM010000000
VERSION     DAVLHM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.009"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VXE45_000547"
     CDS             complement(<1..137)
                     /locus_tag="VXE45_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0788635.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            314..1759
                     /gene="cps4A"
                     /locus_tag="VXE45_000548"
     CDS             314..1759
                     /gene="cps4A"
                     /locus_tag="VXE45_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0788636.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVITALVLLVALLGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAVYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1761..2492
                     /locus_tag="VXE45_000549"
     CDS             1761..2492
                     /locus_tag="VXE45_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0788637.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKVKELFVDNPRKIIMDQLI"
     gene            2501..3193
                     /gene="cpsC"
                     /locus_tag="VXE45_000550"
     CDS             2501..3193
                     /gene="cpsC"
                     /locus_tag="VXE45_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV0788638.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSMTRIYVVNRNQGEKSGLTNQDLQAGSSLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLHMT
                     LLGIVPNLNKLK"
     gene            3203..3892
                     /gene="cpsD"
                     /locus_tag="VXE45_000551"
     CDS             3203..3892
                     /gene="cpsD"
                     /locus_tag="VXE45_000551"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEV0788639.1"
                     /translation="MPTLEIAQKKLEFVKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PEEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GFYGNYGKKII"
     gene            3903..5270
                     /locus_tag="VXE45_000552"
     CDS             3903..5270
                     /locus_tag="VXE45_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0788640.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYVQYTSE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5274..6017
                     /locus_tag="VXE45_000553"
     CDS             5274..6017
                     /locus_tag="VXE45_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEV0788641.1"
                     /translation="MRDRIQLLGVTIDLLTMNETIDIVEQYVLEKRPLHLMGVNADKI
                     NQCHTDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEVLQDMLKVFKRDYPNLIVIGHRNGYFSEEDEQAIQEDIREKNPDFVF
                     IGITSPKKEYIIQKFMDSGVNSVFMGVGGSFDVLSGHIQRAPLWMQKSNLEWLFRVAN
                     EPKRLFKRYFVGNISFIGRVLKAKRGVKY"
     gene            6014..6838
                     /locus_tag="VXE45_000554"
     CDS             6014..6838
                     /locus_tag="VXE45_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV0788642.1"
                     /translation="MNQTEMIRLIQKVELDAIKEFKKICEENDIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREAYDKLPSVFKDRIIAGKYQVLTYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSVLRKIYFGKVYWYRFLASLGTTYVGDH
                     VDMHSTKQKLIIGFFKKLGFAKLFPQNSVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDTFFKVPTEYDRYLKRLYGENYLYEEPSDDEKKSHLGGH"
     gene            6840..7715
                     /locus_tag="VXE45_000555"
                     /pseudo
     CDS             6840..7715
                     /locus_tag="VXE45_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            7719..9056
                     /locus_tag="VXE45_000556"
     CDS             7719..9056
                     /locus_tag="VXE45_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV0788643.1"
                     /translation="MSYLFLLCLTLFLLTIFYFFAFIQDLIAPPVVMSVMFLISSVFA
                     LVNSKNWNIEYSGIAYILIISGIIIFSLPLMALKSPNFNTEVKIADRLIDIQFWKIAL
                     TIIIDLFILYLYRKEIYNLVLSNGYTGSNIQWFFRNATSYEGELTVRTFIRVLIRVID
                     VSAYIFGYTFINNFLIYRHKRPKDILLLVPLLIFISKTLISGGRQDIIKILIAYVIMM
                     YIQQKRKVGWNRVISHKYIHLGFVGLIAGIPAFYYSLFLAGRSTTRTLFESVSTYLGG
                     SIQHFNQYIENPLDPGEVFGSETLVPILNILGEMGLVNYRSTIHLEFRTLGVTVGNVY
                     TFFRRPLHDFGLVGMYVFVFAVGAFFAIYYLVLRKKQVGFNLDIHTIIYSYVFYWIFL
                     SSIEQYSFTMISLYTLVFIVLVYFMAIFYWCTDFKRGKLIFKISDSSIKLKEE"
     gene            9079..10500
                     /locus_tag="VXE45_000557"
     CDS             9079..10500
                     /locus_tag="VXE45_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788644.1"
                     /translation="MNTKIKNIITSFSYVISSNLLIVLTSSLVVLIFPKIMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYTNLDRKQFYSQMILFSSFLMLISLVLF
                     TLNLITVRDENARYIYNMAIISMIVTNLRTLYVYILQMTNRLKDSSVILISDRVLYVL
                     LLFMFIVFGWHEYKVMIWADILGRTFSLMLSFWICKDIVFQPLSKFILDFKESLDNIR
                     VGINLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVIFP
                     LIKRTKTENLPKIYSNLRNALMLVMFAILLFYYPLKFILDIWLPAYKDALVFMALIFP
                     MSVYEGKMALVINTYLKAMRMEKDILKINALVMLTSMVVTLVTTLLLNNLGLTVVSIV
                     ILLALRSIIAELILSKKLKISVKQDIALELLMTIIFISSSWYLSIWIAVIIYLLAYTL
                     YLYLKHKDIRMYIEYFKNHKKIS"
     gene            10564..11652
                     /gene="wecB"
                     /locus_tag="VXE45_000558"
     CDS             10564..11652
                     /gene="wecB"
                     /locus_tag="VXE45_000558"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEV0788645.1"
                     /translation="MKKIMLVFGTRPEAIKMCSLVNELRKQEDMKTVVCVTGQHKEMV
                     SPVLDLFGVQPDYDLEIMKANQNLFSITISILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIANYHFAPTELAKENLIKE
                     GRNNIYVTGNTVIDALTTTVQKDYTHPDLDLNDGNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYDDVKVIYPIHKNPLVRETATEIFGDTERIQIIEPLDVLDFHNFMNHSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKMLLDDPE
                     EYKKMSQASNPYGNGDASKQIVRILRGI"
     gene            11691..12560
                     /gene="rfbA"
                     /locus_tag="VXE45_000559"
     CDS             11691..12560
                     /gene="rfbA"
                     /locus_tag="VXE45_000559"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0788646.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12561..13157
                     /locus_tag="VXE45_000560"
     CDS             12561..13157
                     /locus_tag="VXE45_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0788647.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            13167..14216
                     /gene="rfbB"
                     /locus_tag="VXE45_000561"
     CDS             13167..14216
                     /gene="rfbB"
                     /locus_tag="VXE45_000561"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0788648.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            14282..15133
                     /gene="rfbD"
                     /locus_tag="VXE45_000562"
     CDS             14282..15133
                     /gene="rfbD"
                     /locus_tag="VXE45_000562"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0788649.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            15209..15643
                     /locus_tag="VXE45_000563"
     CDS             15209..15643
                     /locus_tag="VXE45_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788650.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTF
                     LSGKAENQVITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            15716..15973
                     /locus_tag="VXE45_000564"
     CDS             15716..15973
                     /locus_tag="VXE45_000564"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788651.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLERDWEALPADERLQKRQEHLQPLMEDFFA"
     gene            16019..16165
                     /locus_tag="VXE45_000565"
     CDS             16019..16165
                     /locus_tag="VXE45_000565"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788652.1"
                     /translation="MEYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQW
                     TLLA"
     gene            16236..16394
                     /locus_tag="VXE45_000566"
     CDS             16236..16394
                     /locus_tag="VXE45_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0788653.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            16593..18575
                     /locus_tag="VXE45_000567"
     CDS             16593..18575
                     /locus_tag="VXE45_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0788654.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDGYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVMAPVNEEFLNSKGDDFAKATDPNSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            18875..24193
                     /locus_tag="VXE45_000568"
     CDS             18875..24193
                     /locus_tag="VXE45_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0788655.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQ
                     NDNAGKPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYD
                     KDGWFWEYKTPGNSTWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTL
                     PAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKV
                     TYDTIQSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKIN
                     ETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLL
                     SSISFLGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVS
                     TDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFP
                     EYTKELPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFG
                     SQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDF
                     KTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDA
                     AYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRF
                     AIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAA
                     NYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDN
                     GSTYKWTPEMRVELVDANNNKVVVTRKSNDVNSPQYRKRTVTLNGRVIQDGSAYLTPW
                     NWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVK
                     DGKITLDLLANQPYVFYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEI
                     VKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE
                     VTTYTNKSLALNYVKAYAHNTRRDNATVDNTSYFQNMYAFFTTGSDVSNVTLTLSREA
                     GDQATYFDEIRTFENNSSMYGENHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRT
                     HLSEKHDPYTQRGWNGKKVDDVIDGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYR
                     VTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTG
                     AETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALK
                     NYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTA
                     LVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWGGGDVGKPATMVLKEPTEITGLR
                     YVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTG
                     TKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQA
                     SMKYATDNHLLTERMMEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDY
                     KQEIARPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(24360..26519)
                     /locus_tag="VXE45_000569"
     CDS             complement(24360..26519)
                     /locus_tag="VXE45_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0788656.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VXE45_000570"
     CDS             complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VXE45_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0788657.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            27178..27705
                     /locus_tag="VXE45_000571"
     CDS             27178..27705
                     /locus_tag="VXE45_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0788658.1"
                     /translation="MATALVLGYSTFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            27775..28104
                     /gene="gpsB"
                     /locus_tag="VXE45_000572"
     CDS             27775..28104
                     /gene="gpsB"
                     /locus_tag="VXE45_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0788659.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            28125..28505
                     /gene="rnpB"
                     /locus_tag="VXE45_000573"
     ncRNA           28125..28505
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXE45_000573"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            28590..29747
                     /locus_tag="VXE45_000574"
     CDS             28590..29747
                     /locus_tag="VXE45_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0788660.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFDEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            29760..31154
                     /gene="mapZ"
                     /locus_tag="VXE45_000575"
     CDS             29760..31154
                     /gene="mapZ"
                     /locus_tag="VXE45_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0788661.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            31230..32654
                     /gene="gndA"
                     /locus_tag="VXE45_000576"
     CDS             31230..32654
                     /gene="gndA"
                     /locus_tag="VXE45_000576"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0788662.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            32666..33355
                     /locus_tag="VXE45_000577"
     CDS             32666..33355
                     /locus_tag="VXE45_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0788663.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            33453..34415
                     /gene="cbpC"
                     /locus_tag="VXE45_000578"
     CDS             33453..34415
                     /gene="cbpC"
                     /locus_tag="VXE45_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0788664.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            34434..35432
                     /gene="cbpJ"
                     /locus_tag="VXE45_000579"
     CDS             34434..35432
                     /gene="cbpJ"
                     /locus_tag="VXE45_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0788665.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(35550..36782)
                     /locus_tag="VXE45_000580"
     CDS             complement(35550..36782)
                     /locus_tag="VXE45_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0788666.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEIVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTLFLVLSPFSLI
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(36941..37411)
                     /locus_tag="VXE45_000581"
     CDS             complement(36941..37411)
                     /locus_tag="VXE45_000581"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788667.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(37311..37649)
                     /locus_tag="VXE45_000582"
     CDS             complement(37311..37649)
                     /locus_tag="VXE45_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEV0788668.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            38312..38590
                     /locus_tag="VXE45_000583"
     CDS             38312..38590
                     /locus_tag="VXE45_000583"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788669.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSAQVPWQ"
     gene            38765..39643
                     /gene="mvk"
                     /locus_tag="VXE45_000584"
     CDS             38765..39643
                     /gene="mvk"
                     /locus_tag="VXE45_000584"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0788670.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            39625..40578
                     /gene="mvaD"
                     /locus_tag="VXE45_000585"
     CDS             39625..40578
                     /gene="mvaD"
                     /locus_tag="VXE45_000585"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0788671.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            40565..41572
                     /locus_tag="VXE45_000586"
     CDS             40565..41572
                     /locus_tag="VXE45_000586"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0788672.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAESTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            41556..42566
                     /locus_tag="VXE45_000587"
     CDS             41556..42566
                     /locus_tag="VXE45_000587"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0788673.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            42644..43342
                     /locus_tag="VXE45_000588"
     CDS             42644..43342
                     /locus_tag="VXE45_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0788674.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            43339..44334
                     /locus_tag="VXE45_000589"
     CDS             43339..44334
                     /locus_tag="VXE45_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0788675.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            44348..44980
                     /locus_tag="VXE45_000590"
     CDS             44348..44980
                     /locus_tag="VXE45_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0788676.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            44981..45223
                     /locus_tag="VXE45_000591"
     CDS             44981..45223
                     /locus_tag="VXE45_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0788677.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            45148..45459
                     /locus_tag="VXE45_000592"
     CDS             45148..45459
                     /locus_tag="VXE45_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0788678.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLT
                     S"
     gene            45484..45750
                     /locus_tag="VXE45_000593"
                     /pseudo
     CDS             45484..45750
                     /locus_tag="VXE45_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            45900..46139
                     /locus_tag="VXE45_000594"
     CDS             45900..46139
                     /locus_tag="VXE45_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788679.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            46220..47041
                     /gene="cbpG"
                     /locus_tag="VXE45_000595"
     CDS             46220..47041
                     /gene="cbpG"
                     /locus_tag="VXE45_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0788680.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            47060..48082
                     /gene="cbpF"
                     /locus_tag="VXE45_000596"
                     /pseudo
     CDS             47060..48082
                     /gene="cbpF"
                     /locus_tag="VXE45_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(48210..48823)
                     /locus_tag="VXE45_000597"
                     /pseudo
     CDS             complement(48210..48823)
                     /locus_tag="VXE45_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        15228 a         8301 c        10713 g        14581 t
ORIGIN      
        1 tttcctttct gttgataggc tagtagcaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatta aagatgcaga
      241 tagtaaaaaa aatgtagaca ttaccgtaaa aaagtgatat aatcgtatga tgttcaaggt
      301 ataggtgtta atcatgagta gacgttttaa aaaatcacgt tcacagaaag tgaagcgaag
      361 tgttaatatc gttttgctga ctatttattt attgttagtt tgttttttat tgttcttaat
      421 ctttaagtac aatatccttg cttttagata tcttaaccta gtgataactg cgttagtcct
      481 actagttgcc ttgctagggc tactcttgat tatctataaa aaagctgaaa agtttactat
      541 ttttctgttg gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag tacagcagtt
      601 tgttggactg actaatcgtt taaatgcgac ttctaattac tcagaatatt caatcagtgt
      661 cgctgtttta gcagatagtg atatcgaaaa tgttacgcaa ctgacgagtg tgacagcacc
      721 gactgggact gataatgaaa atattcaaaa actactagct gatattaagt caagtcagaa
      781 taccgatttg acggtcaacc agagttcgtc ttacttggca gtttacaaga gtttgattgc
      841 aggggagact aaggccattg tcctaaatag tgtctttgaa aacatcatcg agtcagagta
      901 tccagactac gcatcgaaga taaaaaagat ttataccaag ggattcacta aaaaagtaga
      961 agctcctaag acgtctaaga atcagtcttt caatatctat gttagtggaa ttgacaccta
     1021 tggtcctatt agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg tcaatcgaga
     1081 taccaagaaa atcctcttga ccacaacgcc acgtgatgcc tatgtaccaa tcgcagatgg
     1141 tggaaataat caaaaagata aattaaccca tgcaggcatt tatggagttg attcgtccat
     1201 tcacacctta gaaaatctct atggagtgga tatcaattac tatgtgcgat tgaacttcac
     1261 ttctttcttg aaaatgattg acttattggg aggggtagat gttcataatg atcaagagtt
     1321 ttcagctcta catgggaagt tccatttccc agtagggaat gtccacctag actctgagca
     1381 ggctctaggt tttgtacgtg aacgctactc actagccgat ggagaccgtg atcgtggtcg
     1441 caaccaacaa aaggtcattg tagcaattat tcagaagtta acttctacag aggttttgaa
     1501 aaactatagt agtattcttc aaggattgca ggattctctt caaacaaata tgccgattga
     1561 gactatgata gatttagtga atactcagtt ggaaagtggg gggaattata aagtaaattc
     1621 tcaagattta aaagggacag gtcggatgga tcttccttct tatgcaatgc cagacagtaa
     1681 cctctatgtg atggaaatag atgatagtag tttagctgta gttaaagcag ctatacagga
     1741 tgtgatggag ggtagatgaa atgatagaca tccattcgca tatcgttttt gatgtagatg
     1801 acggtcccaa gtcaagagag gaaagcaagg ctctcttggc agaatcctac aggcaggggg
     1861 tgcgaaccat tgtctctacc tctcaccgtc gcaagggcat gtttgaaact ccggaagaga
     1921 agatagcaga aaactttctt caggttcggg aaattgcaaa agaagtggca gatgatttag
     1981 tcattgctta tggcgcagag atatactata ctctggatgc tctagaaaag ctagaaaaaa
     2041 aagaaattcc tacccttaat gatagtcgtt atgccttgat tgagtttagc atgcatactt
     2101 cctatcgtca gattcatacg ggattgagca atattttgat gttgggaatc acgccagtaa
     2161 ttgctcatat tgaacgttat gatgctttag agaataacga aaaacgtgtt cgtgaactga
     2221 ttgatatggg gtgctatact cagataaata gttatcatgt ttcaaaacct aagttctttg
     2281 gtgaaaaata taaattcatg aaaaagagag ctcggtattt tttggaacgt gatttagttc
     2341 atgtagttgc aagtgacatg cacaatttag acagtagacc tccatatatg caacaggcat
     2401 atgatatcat tgctaagaaa tatggagcga aaaaagtaaa agaacttttt gtagataatc
     2461 ccagaaaaat tataatggat caattaattt aggagaaaat atgaaggaac aaaacacttt
     2521 ggaaatcgat gtattgcaac tattcagagc tttatggaaa agaaagttgg tcattttatt
     2581 agtggcaatt ataacttctt cagttgcttt tgcctacagt acttttgtta tcaaacctga
     2641 gtttactagt atgactcgga tttatgtagt taaccgtaat cagggagaga agtctggttt
     2701 aaccaatcaa gacttgcagg caggatcatc cttggttaaa gactatcgtg aaattatcct
     2761 atcgcaggat gttttggagg aagttgtttc tgatttgaaa ctagatttga cgccaaaaga
     2821 tttggctaat aaaattaaag taacagtacc agttgatacc cgtattgtct ctgtttcagt
     2881 tagtgatcga gttcctgaag aggcaagccg tatcgctaac tctttgagag aagtagctgc
     2941 tcaaaaaatt atcagtatta ctcgtgtttc tgatgtgaca acactggagg aggcaagacc
     3001 ggcgacatca ccgtcttcgc caaatattaa acgcagtaca ctaattggtt ttttggcagg
     3061 agtgattgga actagtgtta tagttcttat tcttgaactt ttggacactc gtgtgaaacg
     3121 tccgaaagat atcgaagata cactgcatat gacacttttg ggaattgtac caaacttgaa
     3181 taagttgaaa taggagagag gaatgccgac attagaaata gcacaaaaaa aactggagtt
     3241 cgttaagaag gcagaagaat attacaatgc cttgtgtaca aatatacagt tgagcggaga
     3301 taaactaaaa gtaatttccg ttacttctgt taaccctgag gaaggaaaaa caactacttc
     3361 cgtaaatata gcaaggtcgt ttgcgcgtgc aggctataaa actcttttga tcgatggcga
     3421 tactcgaaat tcagttatgt caggattttt taaatctcgt gaaaaaatta cagggctaac
     3481 ggaattttta tctgggacag ctgatttatc tcacggttta tgtgatacaa atattgaaaa
     3541 tttatttgta gttcaatcgg gcactgtatc accaaaccct acagccttgt tacaaagtaa
     3601 aaattttaat gatatgattg aaacattgcg taaatatttt gattatatca ttgttgatac
     3661 agcacctatt ggaattgtta ttgatgcggc aattatcact caaaagtgtg atgcgtccat
     3721 cttggtaaca gcaacaggtg aggtgaataa acgtgatgtc caaaaagcga aacaacaatt
     3781 agaacaaaca gggaaactgt tcctaggagt tgttttgaat aaattagata tctcggttga
     3841 taagtatgga gtttacggtt tctatggaaa ttatggtaaa aaaataattt aggaaagatt
     3901 ctatggatga aaaaggattg aaaatttttt tggcagtatt acagagtatt attgtcattt
     3961 tattggttta ttttcttagc tttgttagag agacagaact tgaacgttct tcgatggtta
     4021 tactatacct tctccacttt tttgtattct attttagttc ctatggtaac aattttttta
     4081 aaagagggta cctagttgag tttaatagta ccataagata tatttttttc tttgcaatag
     4141 ctataagtgt attaaacttt tttatagcgg aacggtttag tatctctaga agaggaatgg
     4201 tatacttctt aactttagaa ggaatatcct tatacttgtt aaatttctta gtaaagaaat
     4261 attggaagca tgtgtttttt aatctaaaaa atagcaagaa aattttactg ttaacagtaa
     4321 cgaaaaatat ggaaaaagtt cttgataaat tgctagaatc tgatgaactt tcatggaaat
     4381 tggtagcagt aagtgttttg gataaatctg attttcaaca tgataaaata cctgtaattg
     4441 aaaaggaaaa aattattgaa tttgcaacgc atgaagttgt ggatgaggtg tttgtcaatc
     4501 ttccaggaga gagctacgat attggagaaa ttatctctag gtttgagaca atggggatag
     4561 atgtaactgt aaatcttaaa gcatttgata agaatttggg tcgcaataaa caaattcatg
     4621 agatggtagg attgaatgta gtcactttct ctacaaattt ttataaaact agtcatgtaa
     4681 ttgctaagcg gattattgat atcatgggtg cattggtagg gctgatacta tgtggtttag
     4741 tcagtattgt attggttcct ttgattcgaa aggatggggg ctctgctatt tttgctcaga
     4801 cgcgtatagg aaaaaatggt cgtcagttca ctttttataa gtttcgctct atgtgtgtag
     4861 atgccgaggc gaaaaaaaga gaactcatgg aacaaaatac catgcagggt ggaatgttta
     4921 aggtggacga tgatcctcgt atcacgaaaa ttggtcgttt tatacggaag actagcttgg
     4981 acgagttacc acagttttat aatgttctaa agggagatat gagtttggtt ggcacacggc
     5041 cacctacagt ggacgagtat gttcagtata cttcagaaca gaaacgtcga ctcagcttta
     5101 aacctggtat tacaggttta tggcaggtta gcggccgtag taaaataacc gattttgacg
     5161 atgttgtaaa attagatgtg gcttatattg ataattggac aatctggaaa gatattgaaa
     5221 ttttgcttaa aactgttaaa gttgtattta tgagagatgg agcgaagtga ggaatgaggg
     5281 atagaatcca acttttaggt gtaacaattg atttgcttac gatgaatgaa acgatagata
     5341 ttgtagaaca atatgtatta gaaaaaagac cactacactt gatgggggtg aatgctgata
     5401 aaattaatca gtgtcataca gatgagaaaa tcaaaaaaat cgttaatgag tcaggaatca
     5461 ttaatgcgga tggagcatca gttgttcttg caagtaagtt tttaggaacg cctgttcctg
     5521 aacgagtagc gggtattgat ttgatgcaat gtcttttaga gttgtcaaat aaaaaaggat
     5581 attcagttta cttttttgga gcaaaagaag aagttttgca agatatgctc aaagtattta
     5641 agagagatta tccaaatttg atagttattg gacacagaaa tggctatttt tctgaagagg
     5701 atgaacaagc tattcaagaa gatattcgtg aaaagaaccc tgattttgtg tttattggaa
     5761 ttacgtctcc taaaaaagaa tatattattc aaaaatttat ggatagtggc gtcaattcgg
     5821 tatttatggg agttggcggt agttttgatg tcttgtctgg tcatatccaa cgagcacctc
     5881 tatggatgca aaagtcaaat ttagagtggt tattccgtgt agctaatgag cctaaacgtc
     5941 tctttaaacg ttattttgta gggaatattt cattcatagg aagagtttta aaagcaaaaa
     6001 gaggtgtaaa atattgaacc agacagagat gattcgctta attcaaaaag ttgaattaga
     6061 tgctataaaa gagtttaaaa aaatctgtga agagaatgat atagattttt tcctccgcgg
     6121 tggtagtgta cttggtgcgg tcaaatacga cggctttatt ccatgggatg atgatatgga
     6181 tatcgctgtc cctcgtgaag catacgacaa acttccaagt gttttcaaag atagaattat
     6241 cgctgggaaa tatcaggttc ttacttatca atactgtgat acgttgcatt gctactttcc
     6301 tcgactattc cttttagaag atgaaagaaa acgtttgggc ttgccacgaa ataccaatct
     6361 aggattgcat ttgattgata tcattccttt agatggagca ccaaatcatt cggttttaag
     6421 aaagatttac tttggcaaag tatactggta tcgtttttta gcaagtttag gaacaactta
     6481 tgttggcgac catgtggata tgcattccac taagcaaaaa ctaattattg gtttctttaa
     6541 aaaactagga tttgcaaaac tatttcctca aaattctgta tacagacgct tggataatct
     6601 ctataaaaag tatgattgga aaaagcagaa gtatgcgggg actatcaatg cttctttatt
     6661 tgctaaagaa gttatgccag tagagatttg gggagaagga gtagagaagc cttttgagga
     6721 tactttcttt aaagttccaa cggagtatga tcgctacctg aaaagacttt acggagaaaa
     6781 ctatctttac gaagagccta gtgatgatga aaagaaatcg catttaggag gacactaatt
     6841 tgttttgtta tattattttg cattacaaag tcttagaaga aactatttct tgtgttaaat
     6901 ctataaaaga aggcaattat aatgcaaagc aaatcgttat tattgataat ttttctaata
     6961 atggtactgg tgaaaaacta caagagcttt atgaatcaga tttagaaatt gatgttttga
     7021 ttaaccatga aaatgctggt tttgctcgtg gaaataatgt ggcttatcaa tttgctaagg
     7081 aaaagtataa ccccgatttc atggttatca tgaataacga tattgagata gaaacagaaa
     7141 attttgaaaa aattgtgaca gatatctatc gtgaggaaaa attccatttg ctcgggccag
     7201 atatcttctc gactacttac caacttcacc aaaacccaaa acggttgaca cattatactt
     7261 atggagaagt taaagctcta aatgaaaaat ttaaaaaagg gagccaagtt agtctagctt
     7321 taaaaatcaa atgttggttg aaagctagta aagttcttcg aacagcaatc tatcaaaata
     7381 gacgtaaaaa aggatcagta gactatagaa aacaggtaga aaacccaatt cttcatggtt
     7441 cttttattgt atattcgaga gattttatcg aaaaagagga gtatgctttt aaccctaaca
     7501 ccttcttcta ctatgaaaca gagatattag attatgaagc tgaattaaaa ggatacaaga
     7561 gaatttatac acctaaaatt agagttttgc accatcaaaa tgttgcaact aatcaagttt
     7621 acacgaactt gttagaaaaa accttgtttt caaataaatg caactttaaa tccaccagtt
     7681 attttttgaa gttgatgaaa gaaaacgagg atgtttatat gagttattta tttttacttt
     7741 gccttacatt attcttattg actatattct atttctttgc ttttattcaa gatttaattg
     7801 ctcctccagt agttatgtct gtaatgtttc taattagttc agtatttgca ctggttaatt
     7861 caaaaaactg gaatattgaa tatagtggaa tagcctatat tctcataatt agtggtatta
     7921 ttatattttc gcttccttta atggcattaa aatcacctaa ttttaatact gaggttaaga
     7981 ttgctgatcg attaattgat atccaatttt ggaaaattgc tctaactatt ataattgatc
     8041 tctttatttt gtatctttac aggaaggaaa tatataacct tgttcttagt aatggatata
     8101 cggggtcaaa tattcagtgg ttttttagaa atgcaacgag ttatgaaggt gaattgacag
     8161 tgcgaacttt tattcgagtt ctcattcgtg ttattgacgt atctgcttat atttttggat
     8221 atacttttat taataatttt cttatctatc gccataaacg ccctaaagac atattacttt
     8281 tagtaccttt attaatattt atttcaaaaa ctttaatatc aggaggccgg caagatatta
     8341 ttaaaattct gattgcctat gtaatcatga tgtatatcca acaaaaacgg aaagttggat
     8401 ggaatagagt catatctcat aaatatattc accttggatt tgttggttta atagcaggta
     8461 ttccagcatt ttactactct ttgtttttag ccggtcgttc aacgactagg acgctatttg
     8521 agagtgtttc gacctatcta ggaggctcaa ttcagcattt taatcagtat attgaaaatc
     8581 cattagatcc tggtgaagtt tttggcagtg aaacattggt gcctatatta aatatattag
     8641 gggaaatggg cctagttaat tatcgtagta caattcattt agaatttcgg acactaggag
     8701 ttactgtagg aaatgtttat acttttttta gaagaccctt gcatgatttt ggtctagttg
     8761 gtatgtatgt gtttgtcttt gctgtaggtg ctttttttgc tatttattat ttagttctga
     8821 gaaagaaaca ggttggtttt aatttggata ttcataccat tatttattct tatgtctttt
     8881 attggatttt tttatcatca atcgagcaat actcgttcac aatgattagt ctatatacac
     8941 ttgtatttat tgtgttggtt tactttatgg ctatctttta ctggtgtaca gattttaaaa
     9001 gaggaaaact gatttttaaa atttctgact caagtatcaa attaaaagaa gaataacaga
     9061 atgtatagga gagggtagat gaatactaaa attaaaaata taataactag tttttcttat
     9121 gttatttctt caaatctgct catagtttta acctcatcac tagttgtttt gatttttcct
     9181 aaaataatgg gggtaactga gtacagttac tggcaacttt atatttttta tctgacctat
     9241 atcggttttt tccacttggg ttggattgat gggatttatc tcaaatatgg tggcttagaa
     9301 tatacaaatt tagatagaaa acagttttat tctcagatga ttctattttc tagtttctta
     9361 atgctaatct cgctggtatt atttactttg aacctaataa ctgtaaggga tgaaaacgca
     9421 agatatattt ataatatggc tatcattagc atgatagtca caaacttaag aacactctat
     9481 gtttatatct tgcagatgac aaatcgcttg aaggatagtt cagtcattct aattagtgat
     9541 cgcgttttat atgtactcct tttattcatg tttattgtat ttggatggca tgagtacaag
     9601 gtcatgattt gggctgatat tctaggtcga acattttctc tcatgctttc cttctggatt
     9661 tgtaaagata ttgtgtttca gcctttgtca aaatttatct tagatttcaa ggagtccctt
     9721 gataatatcc gtgttggaat caatttaatg ctatctaaca ttgcgagtag catgattata
     9781 ggcattgttc gtatgggaat tcaatggaat tggaatattg aaacattcgg gaaagtgtca
     9841 ttaactttga gtatatctaa tttattaatg acttttatta atgccattgg attagttatc
     9901 tttcctttga taaagcgaac aaagactgag aatttaccta aaatttattc taatttaaga
     9961 aatgctttga tgttggttat gttcgcaatc ttgctcttct actatccttt aaaatttatt
    10021 cttgatattt ggcttcctgc ttataaggat gccttagttt tcatggccct aatttttcct
    10081 atgtcagttt atgaagggaa aatggctttg gtgataaata catatttaaa agcaatgaga
    10141 atggaaaaag acattctcaa aattaatgct ttggttatgt taactagtat ggtagtgaca
    10201 ttagtgacta ctctactact aaataatttg gggctgacag ttgtatctat agttatttta
    10261 cttgctttaa gaagtataat agctgaatta attttatcca aaaaactgaa gatatcagtc
    10321 aagcaagaca ttgctttaga gttacttatg acgattatat ttatttcttc aagttggtat
    10381 ctctctattt ggattgcagt aataatttat ttattggcgt atactttata tttgtattta
    10441 aagcacaaag atatcagaat gtatatagaa tactttaaaa atcataaaaa aatatcataa
    10501 aaattatata tcaatgaaat ggtagattac atttctacct ttttatccat ttaggaggaa
    10561 acgatgaaaa agataatgct agttttcggt acacgtccag aagcaataaa aatgtgttca
    10621 ttagtcaatg agttgagaaa acaggaagat atgaaaacag ttgtttgtgt aactggtcaa
    10681 cacaaggaga tggttagccc tgttttagat ttatttggag ttcaaccaga ctatgattta
    10741 gaaattatga aggctaatca aaacttgttc tctataacaa taagtatttt agaaaaaata
    10801 aaacctgtgt tagaaaaaga acaaccagat attgttttgg ttcacggtga tactactacg
    10861 acatatgcag cagctttagc ggcattttat ctaggaatta aagttggtca tgttgaagct
    10921 ggattacgaa cttacaacct gcaaagtcct ttcccagaag agttcaacag acaatcgact
    10981 tctattattg caaattatca ttttgctcct acagaattag ctaaagaaaa tctaataaaa
    11041 gagggtagaa ataatatcta tgttactgga aatacagtga ttgatgcact tacaactaca
    11101 gtacaaaagg attatacaca ccccgatcta gatttaaacg atggaaatcg cctcatctta
    11161 ttgactgctc atagacgcga aaatctcgga gaacctatga gacatatgtt tagagctgtt
    11221 aaacgagttt taaatgaata tgacgatgtt aaagtaattt atccaattca taaaaatcca
    11281 ttggtacggg aaacagctac agaaattttt ggagatacag aacgtattca gatcattgaa
    11341 cctttagatg ttcttgattt tcacaacttt atgaatcata gttatatgat tctaactgac
    11401 tcaggagggg ttcaagaaga ggcaccttcg ttaggaaagc ctgtattggt catgcgagat
    11461 acgacagaaa gacctgaagg agtagctgct ggaacgttga aattggttgg gactgatgag
    11521 gagactattt atcaaaactt taagatgctt ttagacgatc ccgaagaata taaaaaaatg
    11581 agtcaagcta gtaatcctta tggaaatggt gatgctagta aacagattgt tcgaatttta
    11641 cgtggaattt gagtgtgttc agataaagta atatagaaag gtaccctact atgaaaggta
    11701 ttattctagc aggtggttcg gggacacgtt tatatccttt gactcgcgct gcatcaaaac
    11761 aacttatgcc ggtttatgat aaaccgatga tttactaccc actttcaaca ttgatgttgg
    11821 ctgggattag ggatattttg attatttcca ctccacagga tttacatcga ttccaagagc
    11881 ttcttcaaga cggatctgag tttgggctca aactttctta tgcagagcaa ccaagtccag
    11941 atggtttggc acaagccttt atcattgggg aagagtttat ttctgatgat agcgttgcgc
    12001 tgatcttagg tgacaatatc tatcacggtt ctgggctttc caagatgcta caaaaggcag
    12061 cgagtaagga gtcgggagca actgtttttg gctaccatgt caaggatcca gagcgctttg
    12121 gtgtggttga gtttgatcag gatatgaagg ctatttctat tgaagaaaag ccagagcaac
    12181 ctcgttcaaa ctatgcagtt acaggtctct atttctatga taatgatgta gtagagattg
    12241 ccaagagtat taaaccaagt cctcgtggtg aactggaaat tacagatgta aacaaggctt
    12301 acctagatcg tggtgatttg tctgttgagc ttatgggacg tggctttgct tggctggata
    12361 ctggaactca tgaaagttta ctagaggctt cacagtacat cgaaacagtg caacggatgc
    12421 aaaatgttca ggtagcaaac ttagaagaaa ttgcttaccg tatgggctat atcagtcgag
    12481 aagatgtatt ggccttagcc caaccactta agaaaaatga atacggacag tatctgctcc
    12541 gtttgattgg agaagcatag atgacagata attttttcgg taagacgctt gcggcacgca
    12601 aggttgaagc tattccaggc atgttggagt ttgatatccc cgttcatgga gataaccgtg
    12661 gctggtttaa agaaaatttc caaaaggaaa aaatgcttcc acttggattt ccagagtctt
    12721 tctttgcaga aggaaaattg caaaacaatg tatccttctc acgtaaaaat gtccttcgag
    12781 gtctccacgc agagccttgg gataagtaca tctctgtagc agatggaggg aaagttctgg
    12841 gttcttgggt tgatctacgc gagggtgaaa cctttgggaa tacctatcag acagtgattg
    12901 atgcgagtaa gggaatcttt gttcctcgag gcgtagctaa tggctttcaa gttttatcag
    12961 atacagtgtc atatagctat ctggtcaatg attactgggc tcttgaactc aaacccaagt
    13021 atgcctttgt gaactacgct gatccaagcc ttggtattga atgggaaaat attgcagaag
    13081 cagaggtttc agaagcagac aaacatcatc cactacttaa ggatgtaaaa cctttgaaaa
    13141 aagaagattt ggaataagga aagaatatga ctgaatacaa aaatattatc gtgacaggtg
    13201 gagctggctt tatcggttct aactttgtcc attatgttta cgagaacttt ccagatgttc
    13261 atgtgacagt cctagataag ttgacttatg ctggaaaccg cgcgaatatt gaggaaattt
    13321 taggtaatcg tgttgagtta gttgttggtg acattgctga tgcggagttg gtagacaagt
    13381 tggctgctca agcagatgct atcgttcatt atgcagcgga aagccacaat gataattcgc
    13441 tcaatgatcc atcgccattt attcatacta acttcatcgg aacctatact cttttagaag
    13501 ctgctcgtaa gtatgatatt cgcttccacc atgtatcgac agatgaagtt tatggggatc
    13561 tccctttacg cgaagatttg ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg
    13621 aaacaaaata caacccaagc tctccgtact catcaaccaa ggcagcctca gatttgattg
    13681 tcaaagcctg ggtgcgttct tttggagtca aggcaacgat ttccaactgt tcaaataact
    13741 acggtcctta tcaacatatc gaaaaattca tcccacgtca gattactaac atcctaagtg
    13801 gtatcaagcc aaaactttac ggtgaaggta agaacgttcg tgattggatt cataccaatg
    13861 accattcttc aggagtttgg acaatcttga caaaagggca aatcggtgaa acctacttga
    13921 ttggggctga tggtgagaag aacaataagg aagttttgga acttatcctt aaggaaatgg
    13981 gacaagctgc ggatgcctat gatcatgtga ctgaccgtgc aggacatgac cttcgctatg
    14041 cgattgatgc tagcaagctc cgtgatgagt tggggtggaa acctgaattt accaactttg
    14101 aagctgggct caaggcaaca atcaagtggt atacagataa ccaagaatgg tggaaagcag
    14161 agaaagaagc tgttgaagcc aattatgcta agactcagga gattattaca gtataaaaag
    14221 caggaaatag ctgcttttta ttgctatatt gggaagagtt acatattaga aaggtctaga
    14281 gatgatttta attacagggg caaatggcca attaggaacg gaacttcgct atttattgga
    14341 tgaacgtaat gaagaatacg tggcagtaga tgtggctgag atggacatta ccgatgcaga
    14401 aatggttgag aaagtttttg aagaggtgaa accgacttta gtctaccact gtgcagccta
    14461 caccgctgtt gatgcagcag aggatgaagg aaaagagttg gacttcgcca tcaatgtgac
    14521 ggggacaaaa aatgtcgcaa gagcatctga aaagcatggt gcaactctag tttatatttc
    14581 tacggactat gtctttgacg gtaagaaacc agttggacaa gagtgggaag ttgatgaccg
    14641 accagatcca cagacagaat atggacgcac taagcgtatg ggggaagagt tagttgagaa
    14701 gcatgtgtct aatttctata ttatccgtac tgcctgggta tttggaaatt atggcaaaaa
    14761 cttcgttttt accatgcaaa atcttgcgaa aactcataag actttaacag ttgtaaatga
    14821 ccagtacggt cgtccgactt ggactcgtac cttggctgag ttcatgacct acctagctga
    14881 aaatcgtaag gaatttggtt attatcattt gtcaaatgat gcgacagaag acacaacatg
    14941 gtatgatttt gcagttgaaa ttttgaaaga tacagatgtc gaagtcaagc cagtagattc
    15001 cagtcaattt ccagccaaag ctaaacgtcc gctaaactca acgatgagcc tggccaaagc
    15061 caaagctact ggatttgtta ttccaacttg gcaagatgca ttgcaagaat tttacaaaca
    15121 agaagtgaga taagtagtag aatgattttc tagtctaata aaagaggcag ataatgaact
    15181 ccaaaggagc ttaagatgta cgattatctt gttgttggtg ctggtctctt tggcgcatag
    15241 ctttggctca gtttctatta tcgctcacac catccatcag aagtttaatc tgaaggtacc
    15301 caattatcgc caagaagaag attgggctag gatgggttta ccaatcacac gtaaggaaat
    15361 ctctaattgg catatcaagg caagtcaata ctatttagag tccctttata accttttacg
    15421 agaaaagttg ttagaacaac ctcttcttca tgcggatgaa acctcttatc gggtcttaga
    15481 aagtgatagt cagctgacct actattggac ctttttgtct gggaaagctg agaatcaagt
    15541 aatcacgctt taccaccatg atcagtgtcg gagtggttcg gtagtgcaag aattcctagg
    15601 agattattct ggctatgtgc attgtgatat gttgcggcag taacttagga ctttagtcct
    15661 ctagttctgt ctatgcgata gcagtccaag gtttaggagc aaggcgacgc taagcttggt
    15721 aaactgcgaa ccgctagaag cttatcgtca actggaagaa gctgaacttg ttggatgttg
    15781 ggcgcatgtg agaaggaaat tttttgaagt gccccccaag caagcagata aatcatcctt
    15841 aggagctaaa ggtttagctt attgtgatca gttattttcc ttggaaagag actgggaggc
    15901 tttgccagct gatgaacgac tacagaaacg tcaagaacat ctccaacccc taatggaaga
    15961 cttctttgct tagtgccgtc gtcagtcagt tttatcgggt tcaaaactag gaagggcaat
    16021 tgaatacagc ctcaagtatg aagaaacctt taagaccatt ttaaaagacg gacatctggt
    16081 cctttccaat aatctagctg aacgcgccat taaatcattg gttatgggac ggagtaaaag
    16141 agtccagtgg actcttttag cctaagctaa attttaaaaa gcgagggtgg ttattttctc
    16201 aaagttttga aggagctaaa gcaagagcta ttattatgag cttattggaa acagctaaac
    16261 gtcatcaact aaatagtgag aaatatctat cctatcttct agaatgtctt ccaaacgagg
    16321 aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa gttgtacaag
    16381 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact aatctggaga
    16441 tttttcaata gacctcgtta ttgggcggtt acgatattca tattttttgc aaagatgttg
    16501 tttgaaaaat aattttcaaa aattctgaaa attctgttga catctttctg aaaagagtct
    16561 ataatggaga gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta cttgcccttg
    16621 cgggcgtgac attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca
    16681 ctaaaggtga gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt
    16741 tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag
    16801 aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg
    16861 atggattgac ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg
    16921 aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata
    16981 aaaaatcaga tgctctttac cttgttcaag aatcaatcaa aggattggat ggctatgtaa
    17041 aaggggaaat caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc
    17101 agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaacaatg ggagtaatgg
    17161 ctccagttaa tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc
    17221 caaatagtct cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg
    17281 ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta
    17341 aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta
    17401 gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta
    17461 tgaaggacaa tattgtctat actcaacaag actctattac gtatttagtt ggtacaaata
    17521 ttgaccgtca gtcctataaa tacacatcta agaccagcga cgaacaaaag gcatcgacta
    17581 aaaaggctct cttaaacaag gatttccgtc aggctattgc ctttggtttt gatcgtacag
    17641 cctatgcctc tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg
    17701 ttccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat
    17761 tggttactta tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt
    17821 acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta caagcagaag
    17881 gtgtgacttt cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc
    17941 agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat aatgtcatta
    18001 ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg
    18061 ctgctggcga agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc
    18121 catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag
    18181 ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa
    18241 aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat gataaatacg
    18301 ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag
    18361 ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata
    18421 aaggtacaag tgaaccaatc ttatataaat acttggaact tcaagacaag gcagtcactg
    18481 tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa
    18541 aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt
    18601 tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta
    18661 ctgaccccca aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta
    18721 cttgtttcct attgctttct cagttattat ttgttatatt aaaagtataa ttatttttat
    18781 ttatcagggt taagcattgc attttcagag gaaggagtat tttttaaaaa ggaaatgtaa
    18841 acgcttgctc aaaaatgaaa ggatttagaa gtttatgaat aaaggattat ttgaaaaacg
    18901 ttgtaaatat agtattcgga aattttcatt aggtgttgct tctgttatga ttggagctgc
    18961 attctttggg acaagtccgg ttcttgcaga tagcgtgcag tctggttcca cggcgaactt
    19021 accagctgat ttagctactg ctcttgcaac agcaaaagag aatgatgggc gtgattttga
    19081 agcgcctaag gtgggagaag accaaggttc tccagaagtt acagatggac ctaagacaga
    19141 agaagaacta ttagcacttg aaaaagaaaa accggctgaa gaaaaaccaa aagaggataa
    19201 acctgcagct gctaaacctg aaacccctaa gacggtaacc cctaagacgg taactcctga
    19261 atggcaaacg gtagagaaaa aagaacaaca gggaacagtc actatccgag aagaaaaagg
    19321 tgtccgctac aaccaactat cctcaactgc tcaaaatgat aacgcaggca aaccagccct
    19381 gtttgaaaag aagggcttga ccgttgatgc caatggaaat gcaactgttg atttaacctt
    19441 caaagaagat tctgaaaagg gcaaatcacg ctttggtgtc ttcttgaaat ttaaagatac
    19501 caataataat gtttttgtcg gttatgacaa ggatggctgg ttctgggaat acaaaactcc
    19561 aggtaatagc acatggtata aaggcaaccg tgttgctgct cctgaaacag gatcaataaa
    19621 ccgtctttct atcactctca agtcagacgg tcagctaaat gccagcaata acgatgtcaa
    19681 tctctttgac acagtgactc taccagctgc ggtcaatgac catcttaaaa atgagaagaa
    19741 gattcttctc aaggcgggct cttatgacga tgagcgaaca gttgttagcg ttaaaacgga
    19801 taaccaagag ggggtaaaaa cagaggatac ccctgctgaa aaagaaacag gtcctgaagt
    19861 tgatgatagc aaggtgactt atgacacgat tcagtctaag gtcctcaaag cagtgattga
    19921 ccaagccttc cctcgtgtca aggaatacac cttgaatgga catactttgc caggacaggt
    19981 gcaacagttc aaccaagtct ttatcaataa ccaccgaatc acccctgaag tcacttataa
    20041 gaaaatcaat gagacaacag cagagtactt gatgaagctt cgcgatgatg ctcacttaat
    20101 caatgcggaa atgacagtac gcttgcaagt tgtggacaat caattgcact ttgatgtgac
    20161 caagattgtc aaccacaatc aagtcactcc aggtcaaaag atcgatgacg aaagaaaact
    20221 actttcttct attagtttcc tcggcaatgc tttagtctct gtttctagtg atcaaactgg
    20281 tgctaagttt gatggggcaa ccatgtcaaa caatacacat gtcagcggag atgatcatat
    20341 cgatgtaacc aatccaatga aggatttggc taagggttac atgtatggat ttgtttctac
    20401 agataagctt gctgctggtg tttggagtaa ctctcaaaac agctatggtg gtggttcgaa
    20461 tgactggact cgtttgacag cttataaaga aacagtcgga aatgccaact atgtaggaat
    20521 ccacagctct gaatggcaat gggaaaaagc ttataagggc attgttttcc cagaatacac
    20581 gaaggaactt ccaagtgcta aggttgttat cactgaagat gccaatgcag acaagaaagt
    20641 tgattggcag gatggtgcca ttgcttatcg tagcattatg aacaaccctc aaggttggga
    20701 aaaagttaag gatatcacag cttaccgtat cgcgatgaac tttggttctc aagcacaaaa
    20761 tccattcctt atgaccttgg atggtatcaa gaaaatcaat ctccacacag atggtcttgg
    20821 gcaaggtgtt ctccttaaag gatatggtag tgaaggtcat gactctggtc acttgaacta
    20881 tgctgatatt ggtaagcgta tcggtggtgt cgaagacttc aagaccctaa ttgagaaggc
    20941 taagaaatat ggagctcatc taggtatcca tgttaacgct tcagaaactt atcctgagtc
    21001 taaatatttc aatgaaaaaa ttctccgtaa gaatccagat ggaagctata gctatggttg
    21061 gaactggcta gatcaaggta tcaacattga tgctgcctat gacctagctc atggtcgttt
    21121 ggcacgttgg gaagatttga agaaaaaact tggtgacggt ctcgacttta tctatgtgga
    21181 cgtttggggt aatggtcaat caggtgataa cggtgcctgg gctacccacg ttcttgctaa
    21241 agaaattaac aaacaaggct ggcgctttgc gatcgagtgg ggccatggtg gtgagtacga
    21301 ctctaccttc catcactggg cagctgactt gacctacggt ggctacacca ataaaggtat
    21361 caacagtgcc atcacccgct ttatccgtaa ccaccaaaaa gatgcttggg taggggacta
    21421 cagaagttat ggtggtgcag ccaactatcc actgctaggt ggctacagca tgaaagactt
    21481 tgaaggctgg caaggaagaa gtgactacaa tggctatgta actaacttat ttgcccatga
    21541 cgtcatgacc aagtacttcc aacacttcac tgtaagtaaa tgggaaaatg gtacaccggt
    21601 gactatgacc gataacggta gcacctataa atggactcca gaaatgcgag tggaattggt
    21661 agatgctaac aataataaag tagttgtaac tcgtaagtca aatgatgtca atagtccaca
    21721 atatcgcaaa cgtacagtaa cgctcaacgg acgtgtcatc caagatggtt cagcttactt
    21781 gactccttgg aactgggatg caaatggtaa gaaactttct actgataagg aaaagatgta
    21841 ctacttcaat acgcaggccg gtgcaacaac ttggaccctt ccaagtgatt gggcaaagag
    21901 caaggtttac ctttacaagc taactgacca aggtaagaca gaagagcaag aactaactgt
    21961 aaaagatggt aaaattaccc tagatcttct agcaaatcaa ccatacgttt tctatcgttc
    22021 gaaacaaacc aatcctgaaa tgtcatggag tgaaggcatg cacatctatg atcaaggatt
    22081 taatagcggt accttgaaac actggaccat ttcaggcgat gcttctaagg cagaaattgt
    22141 caagtctcaa ggggcaaacg atatgcttcg tattcaagga aacaaagaaa aagttagtct
    22201 cactcagaaa ttaactggtt tgaaaccaaa taccaagtat gccgtttatg tcggtgtcga
    22261 taaccgtagt aatgccaagg cgagcatcac tgtaaacact ggtgaaaaag aagtgactac
    22321 ttataccaat aagtctctcg ctctcaacta tgttaaggcc tacgcccaca atacacgtcg
    22381 tgacaatgct acagttgaca atacaagtta cttccaaaac atgtacgcct tctttacaac
    22441 tggatcggac gtatcaaatg ttactcttac tttaagtcgc gaagctggtg atcaagcaac
    22501 ttactttgat gaaattcgta cctttgaaaa caattcaagc atgtacggag aaaaccatga
    22561 tacaggtaaa ggcaccttca aacaagactt tgaaaatgtt gctcagggta tcttcccatt
    22621 cgtagtgggt ggtgtcgaag gtgttgaaga caaccgcact cacttgtctg aaaagcatga
    22681 tccatataca caacgtggtt ggaacggtaa gaaagttgat gatgttatcg atggaaattg
    22741 gtcactcaag accaatggac tggttagccg tcgtaacttg gtttaccaaa ccatcccaca
    22801 aaacttccgc tttgaagctg gtaagaccta ccgtgtaacc tttgaatacg aagcaggttc
    22861 agataatacc tatgcttttg tagtcggtaa gggagaattc cagtcaggtc gtcgtggcac
    22921 tcaagcaagc aacttagaaa tgcatgaatt gccaaatact tggacagatt ccaagaaagc
    22981 caagaaggca accttcctcg tgacaggtgc agaaacagga gatacttggg taggtatcta
    23041 ctcaactgga aatgcaagta atactcgtgg tgattctggt ggaaatgcca acttccgtgg
    23101 ttataacgac ttcatgatgg ataatcttca aatcgaagaa attaccctaa caggtaagat
    23161 gttgacagaa aatgctctga agaactactt gccaacggtt gccatgacta actacaccaa
    23221 agagtctatg gatgctttga aagaggcggt ctttaacctc agtcaggccg atgatgatat
    23281 cagtgtggaa gaagcgcgtg cagagattgc caagattgaa gctttgaaga atgctttggt
    23341 tcagaagaaa acggctttgg tagcagatga ctttgcaagt cttacagctc ctgctcaggc
    23401 tcaagaaggt cttgcaaatg cctttgatgg caatgtgtct agtctatggc atacatcatg
    23461 gggcggagga gatgtaggca agcctgcaac catggtcttg aaagaaccaa ctgaaatcac
    23521 tggacttcgt tatgttccac gtggatcagg ttcaaatggt aacttgcgag atgtgaaact
    23581 tgttgtgaca gatgagtctg gcaaggagca tacctttact gcaactgatt ggccaaataa
    23641 caacaaacca aaagatattg actttggtaa gacaatcaag gctaagaaaa ttgtccttac
    23701 tggtaccaag acatacggag atggtggaga taaataccaa tctgcagcgg aacttatctt
    23761 tactcgtcca caggtagcag aaacacctct tgacttgtca ggctatgaag cagctttggt
    23821 taaggctcag aaattaacag acaaagacaa tcaagaggaa gtagctagcg ttcaggcaag
    23881 catgaaatat gcgacggata accatctctt gacggaaaga atgatggaat actttgcaga
    23941 ttatctcaac caattaaaag attctgctac gaaaccagat gctccaactg tagagaaacc
    24001 tgagtttaaa cttagatctt tagcttccga gcaaggtaag acgccagatt ataagcaaga
    24061 aatagctaga ccagaaacac ctgaacaaat cttgccagca acaggtgaga gtcaatctga
    24121 cacagccctc ttcctagcaa gtgttagcct agccctatct gctctctttg tagtaaaaac
    24181 gaagaaagac tagtatttag taaaacctct taacaagatt acggaagcag tctctatctt
    24241 ttccaatgag gtttatagta cagaaaaagc ctgagaagat atcttctcag gcttttgtta
    24301 agcacataaa tacaatagtg ctatgaaaaa atcacccaga aaaatctgga tgataaatgt
    24361 tatggttgtg ctggttgagg attctgattt tgttgatcag gggttgtatt tgattgttgc
    24421 gtattattgt taggattggt agtcgtacta ttatttgtgc ttggagtggt tgagctagac
    24481 tgtgaagttg aactatctga tgatgagctt gaactttcag ttgatggggg ttgttgtgga
    24541 gcaggtgagc tccacgtaga acgagcacca tttttaaata cgaattctcc atttctgtag
    24601 agcccctctg gtatattcca atcctctgga ttgcttcctt cagacaggta ggtcatcata
    24661 gagcggtaaa ctttggcagc gaccgtaagg ccattgccta caagtggtgt cagacggtta
    24721 gaatagcctg tccatacagc cattgaatat ttacgcgtat agccagcaaa tagttcatca
    24781 ggtgctacaa attgagaggt cttgatgtgg ttttcaattt cctcgtctgt atagttagag
    24841 gttcctgttt taccagcctg agggagccaa gcaagatagg catttcgtcc agttccataa
    24901 ctcaagactg ttttcatcat gtcggtcatc atataggctg tcgtttcctt catggcacga
    24961 gttccgacat tagagaactc tttttcactc ccatcactaa agacgacttt atggatatac
    25021 attggtttat agtaagttcc accatttgca aaggcagcgt aagcagcagc catcttttca
    25081 ctacttgctc catatttttt gtctgattcg gttgtgttac ttgaaatggc atttgagtag
    25141 tgaatacttg ggtagtcgat tccgagacca tttaggaaag tcttggcgcg gttgagtccg
    25201 accttgttta gagtttccac ggctgggacg tttcgcgatt gttgcagggc gtattgcaag
    25261 gtgatgttgc caaagtagcc cctatcccag ttataaacag gggtatttgt cccagggtag
    25321 ttatagggct catcgtgaac gatagtagca gttgaatcgt agacaccgta ctccaaggca
    25381 ggagcatagt ctgtgatcgg tttcatagtt gatccccagt cgcggtttgt ttctactgct
    25441 tggttaattc cgaaggaaac attacttgac tgatggcgtg ctcctagctg ggcaatgact
    25501 ttaccgttag aaacatcaac aatggtagaa gcgacttgca attcatcgtc tggataggca
    25561 acgtattcgt ctgtattgta aatatcccac agatgttttt gagcttcttg gtctacattt
    25621 gtgtagacat ccatcccagt tgtgagcagg ttatagcctg tttcttcttc cacttgattg
    25681 atgacttcct tgaggtaatt atccatgtaa gcagggtaat tacttgctga tttgagactt
    25741 tgtagtccat cagtaattgg tgtattgact gctttctcat actgttcagc agagatgtag
    25801 ccttgatttt tcatttcaga taagaccaag tttcggcggt cttgggctgc ttctggatgt
    25861 gaataggggt catattggtt tggtgcctga ggcattccag ccagcaaggc taactgaggt
    25921 aaacttaaat tattgaggtc tttaccatag tagttttgag ctgctgtctg cattccatag
    25981 ttcccattag acatgtagac cttatttata tagtaggtca agatttcttg cttggttgct
    26041 ttttgttcta actgaatcgc taaccaagct tcctgagcct tacgagaaat agtctggtcg
    26101 gaagtcgaag ttgaaaagta agtcaactta atcaactgtt gggtgagagt tgatccacct
    26161 tggagggaat tgctttgcag attgcgcaag aaagctccca ggatacggat ggtatcaatc
    26221 cccctgtggt cgaagaagcg atggtcttcg atagaaacga ttgccttaac caaatctgtg
    26281 ggaatatcat tagcttgggc attgacgcgg cgttcagaac ccaagtcagc aatgagttga
    26341 tttttattgt cgtagatttt actagaagtt gttgcaacta gtttactctc ggataggcta
    26401 ggagccttgc taacgtagta gaaaaaaact cctccgccta agacaatggc tgcgataacc
    26461 aagcttaaga agctaatgct cagatacttg attaggcgca gaatcgttgg tttgttcatc
    26521 ttgttttacc acctaataaa tgttctttga taacattgag ataaggaatt tgagggaagg
    26581 caccagcctt gatttcatat ccatattctc gaatatattc aagtggcatt gatttttgtc
    26641 ccttatcttg atgatagaag cgaatcaaat cgaatgccgg caataagtag gtttcttgct
    26701 gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg ggcaaggact tgttccatat
    26761 gctgaatctg atgtggatga aaatttttca tcggaatcgc acgtttttgt tttgtttcct
    26821 tgacttcaaa gtcgatgtaa tatccattat aaacgccaga atagtccgtc gttgaagctt
    26881 gtcgaaaata ggcttcaaca atcttggcac gacttcgttg tggatagtcc acttgtacga
    26941 tttgaatagg agttggtttc ttatgtataa cagccaagcc ctgagacaaa tagtagtcgt
    27001 tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt tgcgaaattt ttgggttgag
    27061 aaagagatgt ttgtcttttt tgtgatgaaa ctttatgtgg atagttgacc ataattctcc
    27121 ttattggtac aataacatca ctttattata ccataatttg cacagaaagg gttaaaaatg
    27181 gctacagctt tggttttagg ctattctact tttgatttgg gtttattttc tgataaggat
    27241 cctcgtctta aattgattaa aaaagcgata cgtaaagatt tagaggctat ggcagcagat
    27301 ggggtgtctt ggcttgtgtt tacaggaagt ttgggttttg aatattgggt tttagaggtt
    27361 gctcaggaga tgaaaaccga atacggtttc cagttggcca ccatttttgc ttttgaaacc
    27421 catggggaaa attggaatga aggtaatcag atgaaactga gtcgctttaa gcaggtagac
    27481 tttgtcaaat atgcttatcc tcgctatgaa cacaaggggc agttaagaga ttaccagcag
    27541 tttttgctgg aaaacacgac tagttcctat cttttttatg atgaagaaaa tgaaacaaaa
    27601 ctagcttatt tttaccaaaa gatgaaaaat caagaggact attttataaa gagattaaca
    27661 tttgatcaat taaatgaact tgctgaaaat ttttccgaaa attgaagctt tgaccttgat
    27721 ttttgtttgc ctttttttat ataataatac tagcaagcga gaatggagag agacatggca
    27781 agtattattt tttcagcgaa agatattttt gaacaagagt ttggacgtga agtccgtggc
    27841 tataataaag tagaagttga cgagttttta gacgatgtca tcaaggacta tgaaacctat
    27901 gctgccttgg tcaagtcact tcgtcaggaa attgcggatt tgaaggaaga attaactcgt
    27961 aaaccgaaac cttcaccagt tcaagcagaa ccccttgaag cggcaattac aagttctatg
    28021 acgaattttg atattttgaa acgcctgaat agattggaaa aagaagtttt tggtaaacaa
    28081 attttagata actcagattt ttaagtagtt atttgagatg tgcaattttt ggataatcgc
    28141 gtgaggagaa ttgcttctca tgaggaaagt ccatgctagc acaggctgtg atgcctgtag
    28201 tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa tcgttacggc agttgaaatg
    28261 gctaagtcct tggataggcc agagtaggct tgaaagtgcc acagtgacgg agtctttctg
    28321 gaaacagaga gagtggaacg cggtaaaccc ctcaagctag caacccaaat tttggtcggg
    28381 gcatggagta tgcggaaacg aacgtagtat tctgactgct atcagctaga gctgttagtg
    28441 gtagacagat gattatcgaa ggaagtggtc ctagtcactt ctggaacaaa acatggctta
    28501 tagaaaattg catataggtt ggggctgaga aattttctca acctcatttt ttaaagtgga
    28561 catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga atttaattta attgcaactg
    28621 tggcagcagg gcttgaggct gtcgttggtc gtgaagtgcg agagttgggc tacgattgtc
    28681 aggttgaaaa tggacgtgtt cgttttcaag gagacgtgag agctattatc gaaaccaacc
    28741 tttggcttcg ggcagcagat cgtatcaaaa ttatcgtagg aacgttccca gctaagactt
    28801 ttgaagagct atttcaggga gttttcgctt tagattggga aaattattta ccacttggag
    28861 ctcggttacc gatttcaaaa gctaaatgtg ttaagtccaa acttcacaat gagcccagtg
    28921 ttcaggctat ttctaagaaa gctgttgtca agaaattgca gaaacactat gctcgcccag
    28981 aaggggttcc tctgatggag aatggcccag agtttaagat tgaggtctct attctcaaag
    29041 atgtggcaac tgtcatgatt gatacgaccg ggtctagcct ctttaaacgt ggttatcgta
    29101 ccgaaaaagg tggcgctcct atcaaggaaa atatggcagc agccatttta caactttcta
    29161 actggtatcc agacaagcct ttgattgatc cgacctgtgg ttcggggact ttctgtattg
    29221 aggcagttat gattgctaga aagatggcgc caggtcttcg tcgctctttt gcatttgatg
    29281 aatggaactg gatcagcgat cgcttgattc aagaagtgcg cacagaagcg gctaaaaaag
    29341 tagaacgtaa gcttgagttg gatatcatgg gctgtgatat tgatgctcgc atggtggaaa
    29401 ttgctaaggc caatgctcag gcagctggtg ttgcaggaga tattactttt aagcagatgc
    29461 gcgtgcagga tttacgttcc gataaaatca atggagtaat catttccaat ccgccttatg
    29521 gtgaacgttt gtcagatgat gcaggagtga ccaagctcta tgctgagatg gggcaagtat
    29581 ttgcaccgct gaaaacttgg agcaaattta tcctgactag tgatgaagct tttgaaagca
    29641 agtatggtag ccaagcagat aagaagcgta agttatacaa cggaaccttg aaagtggatc
    29701 tatatcaata ttttggtcag cgtgtcaaac ggcaagaggt aaaatagaaa gggatactca
    29761 tgagtaaaaa aagacgaaat cgtcataaaa aagaaggtca agaaccgcaa tttgattttg
    29821 atgaagcaaa agagctaaca gttggtcaag ctattcgtaa aaatgaagaa gtggaagcag
    29881 gagtcttgcc tgaggattcc attttggaca agtatgttaa gcaacacaga gatgaaattg
    29941 aggcggataa gtttgcgact cgtcaataca aaaaagagga gttcgttgaa actcagagtc
    30001 tggatgattt aattcaagag atgcgtgagg ctgtagagaa gtcagaagct tcttcggagg
    30061 aagttccatc ttctgaagac atcttactac ccttgcctct ggacgatgag gagcaaggct
    30121 tggatcctct attgctagat gatgaaaatc caacagaaat gactgaagaa gtggaagagg
    30181 agcaaaacct ttctcgtctg gatcaagagg actcagaaaa gaaaagtaaa aaaggcttta
    30241 ttttgaccgt tttggcgctt gtatcagtaa ttatttgtgt cagtgcttat tatgtctatc
    30301 gtcaagtggc tcgttcgacc aaggaaattg aaacttctca atcaactaca gccaatcaat
    30361 cggatgtgga tgattttaat acactttatg acgcctttta cacaaatagc aataaaacgg
    30421 ctttgaaaaa tagccagttt gataaactga gtcaactcaa gactttactt gataagctgg
    30481 aaggtagtcg tgaacatacg cttgccaaat ctaaatatga tagtctagta acgcaaatca
    30541 aggccattca agatgtcaat gcacaatttg aaaaaccagc tattgtggat ggtgtgttgg
    30601 ataccaatgc caaagccaaa tcggatgcta aatttacgga tattaaaact ggaaatacgg
    30661 agcttgataa agtgctagat aaggctatca gtcttggtaa gagccagcaa acaagtactt
    30721 ctagctcaag ttcaagtcaa actagcagct caagttcaag tcaagcaagt tcaaatacga
    30781 ctagtgagcc aaaaccaagt agttcaaatg agactagaag tagtcgcagt gaagtcaata
    30841 tgggtctctc gagtgcaggg gttgctgttc aaagaagtgc cagtcgtgtt gcctataatc
    30901 agtctgctat tgatgatagt aataactctg cctgggattt tgcggatggt gttttggaac
    30961 aaattctagc aacttcacgt tcacgtggct atatcactgg agaccaatat atccttgaac
    31021 gtgtcaatat cgttaacggc aatggttatt acaacctcta taagccagat ggaacctatc
    31081 tctttaccct taactgtaag acaggctact ttgtcggaaa tggcgctggt catgcggatg
    31141 acttggacta ctaagcagtc gttacaaaat tctttctttt caaaagtaaa aatgataaaa
    31201 taaaacaaat gaaacaagag gagtgtcaaa tgacaaaagc taactttggt gtcgtaggta
    31261 tggccgtaat gggtcgtaac cttgccctta atattgaatc acgtggttac acagttgcta
    31321 tctacaaccg tagtaaagaa aaaacggaag atgtgattgc ttgccatcct gaaaagaatt
    31381 ttgtaccaag ctatgacgtt gaaagttttg taaactcaat cgaaaaacct cgtcgtatca
    31441 tgctgatggt tcaagctgga cctggtacag atgctactat ccaagccctt cttccacacc
    31501 ttgacaaagg tgatatcttg attgacggag gaaacacttt ctacaaagat accatccgtc
    31561 gtaatgaaga attggcaaac tcaggtatca actttatcgg tactggagtt tctggtggtg
    31621 aaaaaggtgc ccttgaaggt ccttctatca tgcctggtgg acaaaaagag gcctacgaat
    31681 tggtttcgga tgttcttgaa gaaatctcag ctaaagcacc agaagatggc aaaccatgtg
    31741 tgacttatat cggtcctgat ggagctggtc actatgtgaa aatggttcac aacggtatcg
    31801 agtacggtga tatgcaattg atcgcagaaa gctatgactt gatgcaacac ttgctaggcc
    31861 tttctgcaga ggatatggct gaaatcttta ctgagtggaa caagggtgaa ttggatagct
    31921 acttgatcga aatcacagct gatatcttga gccgtaaaga cgatgaagac caagatggac
    31981 caatcgtaga ctacatcctt gatgctgcag gtaacaaggg aactggtaaa tggacgagcc
    32041 aatcatctct tgaccttggt gtaccattgt cactgattac tgagtcagtg tttgcacgct
    32101 acatttcaac ttacaaagaa gaacgtgtac atgctagcaa ggtgcttcca aaaccagctg
    32161 ccttcaactt tgaaggagac aaggctgaat tgattgaaaa aatccgtcaa gccctttact
    32221 tctcaaaaat catttcatac gcacaaggat ttgctcaatt gcgtgtagcc tctaaagaaa
    32281 acaactggaa cttgccattt gcagatatcg catctatctg gcgtgatggc tgtatcatcc
    32341 gttctcgttt cttgcaaaag attacagatg cttacaaccg cgatgcagat cttgccaacc
    32401 ttcttttgga cgagtacttc ttggatgtta ctgctaagta tcaacaagca gtgcgtgata
    32461 tcgtagctct tgcggttcaa gctggtgtgc cagtgccaac tttctcagca gctattactt
    32521 actttgatag ctaccgttca gctgaccttc cggctaactt gatccaagca caacgtgact
    32581 actttggtgc tcacacttac caacgtaaag acaaagaagg aaccttccac tactcttggt
    32641 atgacgaaaa ataagtaggt cagccatggg gaaacggatt ttattacttg agaaagaacg
    32701 aaatctagct cattttttaa gtttggaact ccagaaagag cagtatcggg ttgatctggt
    32761 agaggagggg caaaaagccc tttccatggc tcttcagaca gactatgatt tgattttatt
    32821 gaacgttaat ctgggagata tgatggctca ggattttgca gaaaaattga gtcgaactaa
    32881 acctgcctca gtcatcatga ttttagatca ttgggaagac ttgcaagaag agctggaagt
    32941 tgttcagcgt tttgcagttt catacatcta taagccagtc tttatcgaaa atctggtagc
    33001 gcgtatttcg gcgatcttcc gaggtcggga cttcattgat caacactgca gtctgatgaa
    33061 agttccaagg acctaccgca atcttaggat agatgttgaa catcacacgg tttatcgtgg
    33121 tgaagagatg attgctctga cccgccgtga gtatgacctt ttggcgacac ttatgggaag
    33181 caagaaagta ttgactcgtg agcaattgtt ggaaagtgtt tggaagtatg aaagtgcgac
    33241 cgagacaaat atcgtagatg tctatatccg ctatctacgg agcaagcttg atgttaaagg
    33301 acaaaaaagc tacattaaaa ccgtgcgtgg tgttggttac accatgcaag aatagaaaag
    33361 cagttgcagt tgtgtaactg cttttttgag gagtttttat atattgacat gcagtcgtgt
    33421 ctttgctaca atcgttttag gaggatatat aaatgaaact tttgaaaaaa atgatgcaag
    33481 ttctactagc agtctttttc tttggtttgc tagctacaaa tacggtattt gcgaatacca
    33541 caggtggccg atttgttgat aaggataata gaaaatatta tgtaaaagat gatcataaag
    33601 caatctattg gcataaaata gacggtaaaa cttactattt tggtgatatt ggagagatgg
    33661 ttgtcggttg gcaatactta gaaattcctg gaacaggtta tcgtgatgat ttatttgata
    33721 atcgtccagt cttcgaaatt ggccttcagg agaagtggta ctattttgga caagatggtg
    33781 ctttgctaga acaaacagat aaacaagtac tagaggcaaa aacgtctgaa aatacaggaa
    33841 aagtatacgg tgaacaatat cctctatctg ctgaaaagag aacttattat tttgataata
    33901 attatgctgt aaagacaggc tggatttatg aagacggcaa ttggtattat ttaaataagc
    33961 taggaaattt tggtgatgat tcttacaatc cactaccaat tggtgaagtt gctaagggtt
    34021 ggactcaaga ttttcatgtt actattgaca ttgatagaag caaacctgct ccatggtact
    34081 acctccgttc ctcaggagca atggccactg gctggtatca ggaaggtacc acttggtatt
    34141 atttagacca gccaaatggc gatatgaaaa caggttggca aaaccttggg aacaaatggt
    34201 actatctccg ttcctcagga gctatggcaa ctggttggta tcaagatggt tcaacttggt
    34261 actatttaga tccttctaat ggagatatga aaataggttg gacaaaagta aatggaaaat
    34321 ggtattatct caattcaaat ggagcaatgg ttacaggtag tcaaactatc gatggtaaag
    34381 tttataactt cgcttcatct ggtgagtgga tttaatgttg gaggatatat aaaatgaagc
    34441 ttttgaaaaa aactatgcaa gctggactaa cagtaatttt ctttggtttg ctagctacga
    34501 atacagtatt tgcagataac tctgaaggat ggcagtttgt ccaagaaaac ggtagaacct
    34561 attacaaaaa gggggacctc aaagaaacct actggcgagt gattgatggt aagtactatt
    34621 attttgattc tctatctgga gagatggttg tcggctggca atatatcccg tttccatcta
    34681 aaggtagtac aattggtcct tacccaaatg gtatcagatt agaaggtttt ccaaagtcag
    34741 agtggtacta ctttgataaa aatggagtgc tacaagagtt tgttggttgg aaagaattag
    34801 agattaaaac tcaagacagt gttggaagaa agtatgggga aaaacgtgaa aattcagaag
    34861 ataaagaaga gaagcgttat tacacgaact attactttaa tcaaaatcat tctttagaga
    34921 caggttggct ttatgatcag tctaactggt attatctagc taaaacagaa attaatggag
    34981 aaaactatat tggtggtgaa agacgtgcag gttggataaa tgatgcttca gcttggtact
    35041 acctagatcc agcaactggt attatgcaaa caggttggca atatctaggt aataagtggt
    35101 actacctccg ttcctcagga gcaatggcca ctggctggta tcaggaaggt accacttggt
    35161 attatttaga ccacccaaat ggcgatatga aaacaggttg gcaaaacctt gggaacaaat
    35221 ggtactatct ccgttcatca ggagctatgg caactggttg gtatcaagat ggttcaactt
    35281 ggtactacct aaatgcaggt aatggagaca tgaagacagg ttggttccag gtcaatggca
    35341 actggtacta tgcttatagc tcaggtgctt tggcagtgaa tacgaccgta gatggctatt
    35401 ctgtcaacta taatggcgaa tgggttcggt aatgacaggg cgcttataat tatattagaa
    35461 cactcgctta atcaaagaag tgactttgtt gtacttgacc tgacgattgg ggagattaaa
    35521 agcatgtgaa atctacacat gctttttcgt tagttatgag tgttgaactt gactaaccat
    35581 tgacaaaaga taagagcaat caaaataaga tacaaaaata tcaatgctaa ctgcaccgaa
    35641 acgcccgatg ctatggatag ggctaatagg gagagcaggg acggggcgag aatgtctact
    35701 gtgctcagag cagagcccac cgtccccatc ttgtcactgg ggatatgggc aaagacagct
    35761 gcttgtaggc gagggctgag aatgccgata atcgtagaac tgatgaaact ggtcacgaaa
    35821 attacgatat aggcttgaca aaggatacta gttattagag ccaataggga aatctcacag
    35881 aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat tactgctggt catattgcca
    35941 aggatagctc cacaagacat gatgatggag agcagggcga agagttgccc aatgctcagt
    36001 tgtgctagtg tctgttggat gaagcggagg gcaatcagcc gaggggacac atccaagatg
    36061 gcaatcatac tggtcgtcag aaacagtagt atgacggtat cttttaacct caggagcaca
    36121 gccagcgact gtttaagatg ttgaaaatat ttcttaaaac tcagtgctgt atgtgacatt
    36181 tcaatccttt tttcaacctc atacaaggta tgtcgaataa catacaggcc caaaaaggca
    36241 atgacaaaag tcagagtgtt gataagggaa atagtttgaa tactcataac attgataagg
    36301 aatgcgccag ctagattggc gacaatgcgg acaaccctca tcagagactg cctgaacccc
    36361 atggcatcat gcaggtcgtc cttaattaca ctgatgtaga gggcgttcat catgtaggca
    36421 gacaggtagc tcaaggtgtc agagatgagg ttgatgatga caatcataat gactgaaatt
    36481 aatgaaaagg gcgacaagac gagaaatagt gtcaaaatag cgtagagcag gattttgatt
    36541 ttggcaatac agagtgcgtg tttgactcta ttttcttgaa aatctcctag aatcccgaga
    36601 aagagttgcg atagtagggg aactatctct gaaatggaaa tcagtaaaat cgctagcgga
    36661 gcgaaattgt actgagccac ataattgata atggcgaggt agaaaatact gtcgccgaat
    36721 gatgaaaaac agctgtttag cagcaactgt ctatatatgt tgtttgtcca aaataatttc
    36781 atacttttct ccttatgtct gcacatcgaa tgggaattta ttatttaata gacaccaata
    36841 taccccctgc ttcctattcc gaagtcaaac aaatctgctt taccactatc tccttgaaac
    36901 atcagtaaac cgtgatcatc tcgttcagaa catgctaaaa ttacctgttg gattttttca
    36961 tcagtaattt gttttgattg tagacagtgg tttgtagtaa gctagttatt ccgtggcaat
    37021 atcctgtcat catttttaga tgatggttaa aaacaaattc ttgatattta ctaataatat
    37081 ctttgtttcc gtcacaatcg tacatacaaa gatataagat tattccggaa attccttcgc
    37141 accaagaaag ttgtaaattt cctaaatttt cagtattaga agtaactttt tctaataatt
    37201 tttttaattc agcatggaat gtatggagat cattatagaa catagaaggt tctaagactt
    37261 tagaataggc aaataaagca tatgcaattc cacaatatcc atgagcaaag ctatagtcta
    37321 aaatgctttc tttggctgta tctctttgta ggaaataatg ataaatttcc ccatatacta
    37381 ttgtggatga aagttttaag agtattgtca ttggtaaatt gatagtattt tattaatgat
    37441 aataggacac cagattttcc caatgcaaag tctatttcct ctagagtatc ataattctct
    37501 attaatttct tagcggtgac gtttgctaat tgtagatagt attgattttt actgatagaa
    37561 aataaatgta ggagtaacca tagatagcct gcatcaccaa atagcagtga gtattgatat
    37621 tcatatgtat gtgtcgttct aattgtcact gccttcttga tgatagagag tattttagaa
    37681 tccagttctg gggggtacaa tttatttaga ggaaacagta gtccagctat tccgtgttgg
    37741 aatgataaat tacttacgaa atttctaaat tctgttgaag aagtgatcct tccttcagaa
    37801 tttacagttt tatctagtaa aaattgtaga acactattac attctgtttt gtaatcatat
    37861 ttatgttcct ctattttttt aattttgact aaattatttg tttgacttaa atttagtaga
    37921 cattgtaacc aaaatagttg ctcatctgtg agctgacctt gagtatgtga tagttctagt
    37981 aattgaatag gatcctttag gtagattcaa tcaatctata acacaacaac ataataacac
    38041 ttttaggata acttatcaaa tattatagta aaatgaaata ataacaggac aaatcgatca
    38101 ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat tctagtttca
    38161 atctactata gtatatattt ttacatcttg aattgtcaaa ttaagtgcat aagtttcccg
    38221 tagcatactt cataaggcgt tttccactta agaaattttc gtggtcgatt atttagaacc
    38281 tgtattcaca aaaaaatgtt aagctagagt tatgatacgc aaagcatatg atactgattt
    38341 aaacgatcaa gaatgggcga agattgaacc ctatttctcc aaacaccgca cctataaatg
    38401 gccgaaacga gtacttgtta atgagacttt gtacgtcact aaaacaggtt gtcaatggcg
    38461 catgctccct cacgactttc ctctttactt aatggtatgg agtttctttc gtcgttctat
    38521 gacgacaggt tggttccagg tcaatggcag atggtactac gcttatagcg ctcaggtgcc
    38581 ttggcagtga atacgaccgt agatggctat tctgtcaact ataatggcga atgggttcaa
    38641 taatgaaaga agcgattgtg aatggaaaca atcgcttttt ttgtgaaaat ataataaaat
    38701 agataggaaa gaattaatac ttgtatgaaa aataagacgt tttttcgtct agtaaaagga
    38761 aaaaatgaca aaaaaagttg gtgtcggtca ggcacatagt aagataattt taatagggga
    38821 acatgcggtc gtttacggtt atcctgccat ttccctgcct cttttggagg tggaggtgac
    38881 ctgtaaggta gttcctgcag agagtccttg gcgcctttat gaggaggata ccttgtccat
    38941 ggcggtttat gcctcactgg agtatttgaa tatcacagaa gcctgcattc gttgtgagat
    39001 tgactcggct atccctgaga aacgggggat gggttcgtca gcggctatca gcatagcggc
    39061 cattcgtgca gtatttgact actatcaggc tgatctgcct catgatgtac tagaaatctt
    39121 ggtcaatcga gctgaaatga ttgcccatat gaatcctagt ggtttggatg ctaagacctg
    39181 tcttagtgac caacctattc gctttatcaa gaacgtagga tttacagaac ttgagatgga
    39241 tttatccgcc tatttggtga ttgccgatac gggtgtttat ggtcatactc gtgaagccat
    39301 ccaagtggtt caaaataagg gcaaggatgc cctaccgttt ttgcatgcct tgggagaatt
    39361 aacccagcaa gcagaagttg cgatttcaca aaaagatgct gaaggactgg gacaaatcct
    39421 cagtcaagcg catttacatt taaaagaaat tggagtcagt agccctgagg cagacttttt
    39481 ggttgaaacg actcttagcc atggtgctct gggtgccaag atgagcggtg gtgggctagg
    39541 aggttgtatc atagccttgg taaccaattt gacacacgca caagaactag cagaaagatt
    39601 agaagagaaa ggagctgttc agacatggat agagagcctg taacagtacg ttcctacgca
    39661 aatattgcta ttatcaaata ttggggaaag aaaaaagaaa aagagatggt gcctgctact
    39721 agcagtattt ctctaacttt ggaaaatatg tatacagaga cgaccttgtc gcctttacca
    39781 gccaatgtaa cagctgacga attttacatc aatggtcagc tacaaaatga ggtcgagcat
    39841 gccaagatga gtaagattat tgaccgttat cgtccagctg gtgagggctt tgtccgtatc
    39901 gatactcaaa acaatatgcc tacggcagcg ggtctgtcct caagttctag tggtttgtcc
    39961 gccctggtca aggcttgtaa tgcttatttc aagcttggat tggatagaag tcagttggca
    40021 caggaagcca aatttgcctc aggttcttct tctcggagtt tttatggacc actaggagcc
    40081 tgggataagg atagtggaga aatttaccct gtagagacag acttgaaact agctatgatt
    40141 atgttggtgc tagaggacaa gaaaaaacca atctctagcc gtgacgggat gaaactttgt
    40201 gtggaaacct cgacgacttt cgacgactgg gttcgtcagt ctgagaagga ctatcaggat
    40261 atgctgattt atctcaagga aaatgatttt gccaagattg gagaattaac ggagaaaaat
    40321 gccctggcta tgcatgctac gacaaagact gctagtccag ccttttctta tctgacggat
    40381 gcctcttatg aggctatgga ctttgttcgc cagcttcgtg agaaaggaga ggcctgctac
    40441 tttaccatgg atgctggtcc caatgttaag gtcttctgtc aggagaaaga cttggagcat
    40501 ttatcagaaa ttttcggtca tcgttatcgc ttgattgtgt caaaaacaaa ggatttgagt
    40561 caagatgatt gctgttaaaa cttgcggaaa actctattgg gcaggtgaat atgctatttt
    40621 agagccaggg cagttagctt tgataaagga tattcccatc tatatgaggg ctgagattgc
    40681 tttttctgac agctaccgta tctattcaga tatgtttgat ttcgcagtgg acttaaggcc
    40741 taatcctgac tatagcttga ttcaagaaac gattgctttg atgggagact tcctcgctgt
    40801 tcgtggtcag aatttaagac ctttttctct agaaatctgt ggcaaaatgg aacgagaagg
    40861 gaaaaagttt ggtctaggtt ctagtggcag cgtcgttgtc ttggttgtca aggctttact
    40921 ggctctgtat gatgtttctg ttgatcagga gctcttgttc aagctgacta gcgctgtctt
    40981 gcttaagcga ggagacaatg gttccatggg cgaccttgcc tgtattgtgg cagaggattt
    41041 ggttctctac cagtcatttg atcgccagaa ggtggctgct tggttagaag aagaaaactt
    41101 ggcgacagtt ctggagcgtg attggggctt ttcaatttca caagtgaaac caactttaga
    41161 atgtgatttc ttagtgggat ggaccaagga agtggctgta tcgagtcaca tggtccagca
    41221 aatcaagcaa aatatcaatc aaaatttttt aagttcctca aaagaaacgg tggtttcttt
    41281 ggtcgaagcc ttggaacagg ggaaagccga aaaagttatc gagcaagtag aagtagccag
    41341 caagctttta gaaggcttga gtacagatat ttacacgcct ttgcttagac agttgaaaga
    41401 agccagtcaa gatttgcagg ccgttgccaa gagtagtggt gctggtggtg gtgactgtgg
    41461 catcgccctg agttttgatg cggaatcaac caaaacctta aaaaatcgtt gggccgatct
    41521 ggggattgag ctcttatatc aagaaaggat aggacatgac gacaaatcgt aaggacgagc
    41581 atatcctcta tgcccttgag cagaaaagtt cctataatag ctttgatgag gtggagctga
    41641 ttcattcttc cttgcctctt tacaatctgg atgaaatcga tctttcgaca gagtttgctg
    41701 gtcgaaagtg ggactttcct ttttatatca atgccatgac tggtggaagt aataagggaa
    41761 gagaaatcaa tcaaaagctg gctcaggtgg cggaatcctg tggtatttta tttgtaacgg
    41821 gttcttatag cgcagccctc aaaaatccaa cggatgattc tttttctgtc aagtctagtc
    41881 atcccaatct cctccttgga accaatattg gattggacaa acctgtcgag ttaggacttc
    41941 agactgtaga agagatgaat cctgttctat tgcaagtgca tgtcaatgtc atgcaggaat
    42001 tactcatgcc cgagggagaa aggaagttta gaagctggca atcgcatcta gcagattata
    42061 gcaagcaaat tcccgttcct attgtcctca aggaagtggg ctttggaatg gatgccaaga
    42121 caatcgaaag agcctatgaa ttcggtgttc gtacagtgga cctatcgggt cgtggtggca
    42181 ccagctttgc ctatatcgaa aaccgtcgta gtggccagcg tgattacctc aatcaatggg
    42241 gtcagtctac catgcaggcc cttctcaatg cccaagaatg gaaagataag gtcgaactct
    42301 tggttagtgg aggggttcgg aatccgctgg atatgattaa gtgcttggtt tttggtgcta
    42361 aggctgtggg attgtcacga accgttctgg aattggttga aacctacaca gttgaagaag
    42421 tgattggcat tgtccaaggc tggaaagcag atctacgctt gattatgtgt tcccttaact
    42481 gtgccaccat agcagatcta caaaaagtag actatcttct ttatggaaaa ttaaaagaag
    42541 caaaggatca gatgaaaaag gcgtaaccag cgcctttttt tccatcctca gactgaggtg
    42601 acttttttga attgtgataa aatagaaggg agaggatgaa cctatgagaa aatttaaaat
    42661 ctttttattt atcgaagcct gtcttctgac aggagctctg attttgatgg tatcagagca
    42721 tttttcgcgt tttctgctga tactattcct ctttttgctt ttgattcgct actacactgg
    42781 taaagaggga aataatcttc ttttagtagc ggcaaccatt ctcttctttt tcatcgttat
    42841 gctcaatcct tttgtgattc tagctatttt tgttgcggtt atctatagcc tctttcttct
    42901 ttacccgatg atgaaccagg aaaaagagca gaccaatttg gtttttgaag aggtcgtgac
    42961 ggttaagaag gagaaaaatc gttggtttgg aaatcttcat catttttcaa gctaccagac
    43021 ttgccaattc gatgatatca atctctttcg cttcatgggt aaggacacta ttcatctgga
    43081 gagggtcatc ttaaccaatc atgacaatgt cattatcctc agaaagatgg taggaacgac
    43141 caaaatcatc gtacctgtag atgtggaagt cagtctcagc gttaactgtc tctatgggga
    43201 tttgactttt ttcaaccagc ccaagcgagc cctccgcaat gaacactatc atcaagaaac
    43261 aaaagactat ctcaagagta acaagagtgt caagattttc ttgaccacta tgattggtga
    43321 tgtggaggtg gttagaggat gaaaaaacaa gcctatgtca ttattgctct cacctccttc
    43381 ctatttgtct tttttttctc ccacagcttg ctggaaatac ttgattttga ctggtctatc
    43441 tttttgcacg atgtcgaaaa aacagaaaaa tttgtctttt tattgttggt tttcagcatg
    43501 tccatgacct gtctcttagc cctgttttgg cgagggatcg aagagctttc tctaagaaaa
    43561 atgcaggcta atctcaagcg tttattggca gggcaagaag tagttcaggt tgtagatcaa
    43621 gatttggatg ccagtttcaa gtccttatca ggtaaactta accttttgac agaggctctt
    43681 caaaaagctg aaaatcatag ccttgctcag gaagaggaaa tcatcgagaa ggaacggaag
    43741 cgaattgctc gggatttgca cgatacagtc agtcaggagt tgtttgcggc ccacatgatt
    43801 ttatcgggta tcagtcagca ggctttgaaa ttggatagag aaaagatgca gacccagttg
    43861 cagagtgtca cagctatttt agaaacagcc cagaaggatt tgcgggtttt gctcttgcat
    43921 ttgcgaccag ttgaactgga gcagaagagc ttgatagaag ggattcaaat tctcttaaaa
    43981 gagcttgagg acaagagtga tcttagggtt agtctcaagc agaatatgac gaaattgcct
    44041 aagaaaatcg aggagcatat cttccgtatc ctgcaagagt tgattagcaa taccctccgc
    44101 catgcccagg catcttgcct agatgtctac ctctatcaga cagatgttga attgcaactg
    44161 aaggtggtgg acaatgggat tggtttccag ttagggagct tagacgactt gagttatgga
    44221 ctgcgaaata tcaaggagcg ggttgaagat atggcaggga cggttcagtt attaacagct
    44281 cccaagcaag ggctggcagt tgatatccgt attcccctgt tagataagga atgataaagg
    44341 agtaaagatg aaaattttac tagtagatga ccatgaaatg gtccgtttgg gtttgaaaag
    44401 ctactttgac ctccaagacg atgtagaagt tgtgggtgag gcgtccaacg ggtctcaagg
    44461 gattgacttg gccttggaac tgcgtccaga tgtcattgtc atggatattg tcatgcctga
    44521 gatgaatggg attgacgcga ccttagcaat ccttaaagaa tggcctgaag ccaagatttt
    44581 gattgtgacc tcttatttgg acaatgaaaa aatcatgcca gtcttagatg ctggtgccaa
    44641 aggctatatg ctcaagactt ctagtgcaga tgaattgctt catgccgtca gtaaggtagc
    44701 tgctggcgag ctggccattg agcaagaggt tagcaagaag gttgaatacc accgcaatca
    44761 tatggaactt catgaagaat tgactgcgcg tgagcgagat gttctccaac tcatcgccaa
    44821 gggctacgaa aatcagcgca tcgcagatga cctctttatc tctctcaaga cggtcaagac
    44881 ccacgtgtcc aatattcttg ccaaacttga agtcagcgat cgtacccagg cggctgtcta
    44941 tgcctttcag caccatttgg tggggcaaga ggagttttag atgagtttag cagatttact
    45001 tgaggagcta gaagcagcaa aagactctaa aaaagcaagg tccatggaag cctatatgcg
    45061 ccatcaattt tcttttctag gtattgcggt gcctgaaaga aataaactct ataaaaatat
    45121 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    45181 aaggagccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    45241 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    45301 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacaccc tgaactagaa
    45361 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    45421 caaaacagtg ttttgagcaa tctgcggcta acttcctagt ttgctctttg attttcattg
    45481 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    45541 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    45601 aaccaaacag aattttttat caataaagcc attggctgga ttctgcgaaa ctactccaaa
    45661 acgaatccaa cttgggtaac atgctttatt gatgaaaaca aggaaagaat ggctgaactt
    45721 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    45781 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    45841 ctatagtaga ttaagaaatt tagaatagta ggctataatt acattaggag gctacaataa
    45901 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    45961 gccagttatc gacagtatct gctttgagtg ttatttctag tacgggtgaa gaatatgagg
    46021 taagtgagac actagaaaaa ggtccaggat ctaatgattc ttcattatct gagatttcac
    46081 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    46141 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    46201 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    46261 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    46321 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    46381 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    46441 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    46501 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    46561 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    46621 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    46681 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    46741 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    46801 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    46861 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    46921 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    46981 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    47041 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaagtcg cactagccac
    47101 atttttcttc ggtttgctag ggaccagtac agtatttgca gatgattctg aaggatggca
    47161 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    47221 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    47281 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    47341 gatttctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    47401 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    47461 atatgatagc ccagcagaga aatgagtcta ttattttgaa gatcagcgta gttatcatac
    47521 tttaaaaact ggttggattt acgaagaggg tcattggtat tatttacaga aggatggtgg
    47581 ctttgattcg cgcatcaaca gattggcggt tggagagcta gcacgtggtt gggttaagga
    47641 ttcccctctt acctatgatg aagagaagct aaaagcagct ccatggtact atctagatcc
    47701 aacaactggc attatgcaaa ctggttggca atttctaggt aatagatggt actacctcca
    47761 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    47821 tgctgaaaat ggtgatatga gaactggctg gcaatacctt ggtaacaagt ggtactatct
    47881 ccgttcatca ggagctatgg caactggttg gtatcaggaa ggttcgactt ggtactatct
    47941 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    48001 tgcctatgat tcaggtgctt tagctgttaa taccacagta ggtggttact acttaaacta
    48061 taatggtgaa tgggttaagt aatgaaggct aattgtaaac tgtgatggat acttaacttt
    48121 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    48181 tactgccccc caaaagttag acaaataatt tatccaaagg atttagttct gtactgcaca
    48241 ggactaagtc cttttagttt taccttaatt ctcttgttgt tgtaataatc aatatagtct
    48301 ataatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    48361 tccgatttca gaatcccaaa gaaggactcc accatagtgc ttctctgtga atgcctgttc
    48421 caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg cgataatttc
    48481 actgttaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
    48541 aaattctgtc acatctgtgt agcacttttc cattgtttta gagccttcaa attggccttg
    48601 aatgagattc tctgccttct taccaacgtc tcctttattt tcgtttctgt cgcattttag
    48661 cttgtaaatt gagtactttc atcaagcctt gaactctttt atgatttacc agataaccac
    48721 gatttcttag ttctaaatga acccggcgat aagtataatt tcccttgtgt tcgataaaaa
    48781 tggattgaat ttcagcttta agctcttggt ccttatctgg ttt
//
LOCUS       DAVLHM010000010        47223 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLHM010000010 DAVLHM010000000
VERSION     DAVLHM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.010"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(4..300)
                     /locus_tag="VXE45_000598"
     CDS             complement(4..300)
                     /locus_tag="VXE45_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788681.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(284..2443)
                     /gene="pfbA"
                     /locus_tag="VXE45_000599"
     CDS             complement(284..2443)
                     /gene="pfbA"
                     /locus_tag="VXE45_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0788682.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYSGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVVN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKINNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3573..4799)
                     /locus_tag="VXE45_000600"
     CDS             complement(3573..4799)
                     /locus_tag="VXE45_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0788683.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFKNEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4842..5534)
                     /locus_tag="VXE45_000601"
     CDS             complement(4842..5534)
                     /locus_tag="VXE45_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0788684.1"
                     /translation="MLKWEDLPVEMKSSEVESYYHLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5707..7458)
                     /locus_tag="VXE45_000602"
     CDS             complement(5707..7458)
                     /locus_tag="VXE45_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788685.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDDQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7448..9193)
                     /locus_tag="VXE45_000603"
     CDS             complement(7448..9193)
                     /locus_tag="VXE45_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788686.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9321..9851)
                     /locus_tag="VXE45_000604"
     CDS             complement(9321..9851)
                     /locus_tag="VXE45_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0788687.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(9848..10304)
                     /locus_tag="VXE45_000605"
                     /pseudo
     CDS             complement(9848..10304)
                     /locus_tag="VXE45_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10438..11265
                     /gene="xth"
                     /locus_tag="VXE45_000606"
     CDS             10438..11265
                     /gene="xth"
                     /locus_tag="VXE45_000606"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0788688.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11277..11375
                     /locus_tag="VXE45_000607"
     CDS             11277..11375
                     /locus_tag="VXE45_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0788689.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            11420..11659
                     /locus_tag="VXE45_000608"
     CDS             11420..11659
                     /locus_tag="VXE45_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0788690.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12042..12137
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12537..13118
                     /locus_tag="VXE45_000609"
     CDS             12537..13118
                     /locus_tag="VXE45_000609"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0788691.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13118..14380
                     /locus_tag="VXE45_000610"
     CDS             13118..14380
                     /locus_tag="VXE45_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0788692.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14430..14891)
                     /locus_tag="VXE45_000611"
     CDS             complement(14430..14891)
                     /locus_tag="VXE45_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV0788693.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14888..15652)
                     /locus_tag="VXE45_000612"
     CDS             complement(14888..15652)
                     /locus_tag="VXE45_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0788694.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYYPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15833..16237)
                     /locus_tag="VXE45_000613"
     CDS             complement(15833..16237)
                     /locus_tag="VXE45_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0788695.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVIGQRSEERRVRI"
     gene            complement(16307..17788)
                     /locus_tag="VXE45_000614"
     CDS             complement(16307..17788)
                     /locus_tag="VXE45_000614"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0788696.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQ
                     ILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(17807..18985)
                     /locus_tag="VXE45_000615"
     CDS             complement(17807..18985)
                     /locus_tag="VXE45_000615"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0788697.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKETVGKHYEEVVGYAPSFYIAEVAGGTHVLD
                     "
     gene            19150..20157
                     /gene="galR"
                     /locus_tag="VXE45_000616"
     CDS             19150..20157
                     /gene="galR"
                     /locus_tag="VXE45_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0788698.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20203..21240)
                     /locus_tag="VXE45_000617"
     CDS             complement(20203..21240)
                     /locus_tag="VXE45_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0788699.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21241..21594)
                     /locus_tag="VXE45_000618"
     CDS             complement(21241..21594)
                     /locus_tag="VXE45_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0788700.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21838..22728)
                     /locus_tag="VXE45_000619"
     CDS             complement(21838..22728)
                     /locus_tag="VXE45_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0788701.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22861..23397
                     /locus_tag="VXE45_000620"
     CDS             22861..23397
                     /locus_tag="VXE45_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0788702.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FIGQEVVQFYLDLLIPKN"
     gene            complement(23563..24369)
                     /locus_tag="VXE45_000621"
     CDS             complement(23563..24369)
                     /locus_tag="VXE45_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0788703.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24714..26234)
                     /locus_tag="VXE45_000622"
     CDS             complement(24714..26234)
                     /locus_tag="VXE45_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0788704.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDSIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26227..26955)
                     /locus_tag="VXE45_000623"
     CDS             complement(26227..26955)
                     /locus_tag="VXE45_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788705.1"
                     /translation="MIEYKNVALCYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(26969..27733)
                     /locus_tag="VXE45_000624"
     CDS             complement(26969..27733)
                     /locus_tag="VXE45_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0788706.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGATYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLKNGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27737..28180)
                     /locus_tag="VXE45_000625"
     CDS             complement(27737..28180)
                     /locus_tag="VXE45_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0788707.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28862..29158)
                     /locus_tag="VXE45_000626"
     CDS             complement(28862..29158)
                     /locus_tag="VXE45_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0788708.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29180..30244)
                     /gene="pepA"
                     /locus_tag="VXE45_000627"
     CDS             complement(29180..30244)
                     /gene="pepA"
                     /locus_tag="VXE45_000627"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0788709.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALLGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30645..31346
                     /gene="galE"
                     /locus_tag="VXE45_000628"
     CDS             30645..31346
                     /gene="galE"
                     /locus_tag="VXE45_000628"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0788710.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31769..32728
                     /locus_tag="VXE45_000629"
     CDS             31769..32728
                     /locus_tag="VXE45_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788711.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32718..33674
                     /locus_tag="VXE45_000630"
     CDS             32718..33674
                     /locus_tag="VXE45_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0788712.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            33671..34423
                     /locus_tag="VXE45_000631"
     CDS             33671..34423
                     /locus_tag="VXE45_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0788713.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34519..35484
                     /locus_tag="VXE45_000632"
     CDS             34519..35484
                     /locus_tag="VXE45_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0788714.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35709..35951)
                     /gene="yidD"
                     /locus_tag="VXE45_000633"
     CDS             complement(35709..35951)
                     /gene="yidD"
                     /locus_tag="VXE45_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0788715.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35951..36673)
                     /locus_tag="VXE45_000634"
     CDS             complement(35951..36673)
                     /locus_tag="VXE45_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0788716.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36660..37229)
                     /locus_tag="VXE45_000635"
     CDS             complement(36660..37229)
                     /locus_tag="VXE45_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0788717.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQALDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37248..37976)
                     /locus_tag="VXE45_000636"
     CDS             complement(37248..37976)
                     /locus_tag="VXE45_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0788718.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37976..38716)
                     /gene="xerD"
                     /locus_tag="VXE45_000637"
     CDS             complement(37976..38716)
                     /gene="xerD"
                     /locus_tag="VXE45_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0788719.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38707..39168)
                     /locus_tag="VXE45_000638"
     CDS             complement(38707..39168)
                     /locus_tag="VXE45_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0788720.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39165..39686)
                     /locus_tag="VXE45_000639"
     CDS             complement(39165..39686)
                     /locus_tag="VXE45_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0788721.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39662..40633)
                     /locus_tag="VXE45_000640"
     CDS             complement(39662..40633)
                     /locus_tag="VXE45_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0788722.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40630..41424)
                     /gene="racE"
                     /locus_tag="VXE45_000641"
     CDS             complement(40630..41424)
                     /gene="racE"
                     /locus_tag="VXE45_000641"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0788723.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41631..41879)
                     /locus_tag="VXE45_000642"
     CDS             complement(41631..41879)
                     /locus_tag="VXE45_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0788724.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42135..43760)
                     /gene="treC"
                     /locus_tag="VXE45_000643"
     CDS             complement(42135..43760)
                     /gene="treC"
                     /locus_tag="VXE45_000643"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0788725.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43938..45905)
                     /gene="treP"
                     /locus_tag="VXE45_000644"
     CDS             complement(43938..45905)
                     /gene="treP"
                     /locus_tag="VXE45_000644"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0788726.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46090..46800
                     /gene="treR"
                     /locus_tag="VXE45_000645"
     CDS             46090..46800
                     /gene="treR"
                     /locus_tag="VXE45_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0788727.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            46955..>47223
                     /locus_tag="VXE45_000646"
     CDS             46955..>47223
                     /locus_tag="VXE45_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788728.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYYFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKIMV"
BASE COUNT        13835 a        10720 c         8842 g        13826 t
ORIGIN      
        1 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
       61 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      121 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      181 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      241 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      301 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      361 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
      421 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
      481 ctgtcttatt atcttgttta ttgttgatct tgtcattcat ttgtctatta tctttacttg
      541 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
      601 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
      661 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca ggttctttcc
      721 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
      781 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
      841 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
      901 ctgtttcctt agaattatta ttaactacat tttttgttac agtaatatct gatacttttc
      961 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1021 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1081 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1141 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1201 cacctgaata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1261 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1321 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1381 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     1441 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     1501 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     1561 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     1621 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     1681 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     1741 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     1801 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     1861 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     1921 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     1981 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2041 ccttataact cttattttca ttagtagatg ttactgtaga ttcaactgtt ctgttgtcta
     2101 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2161 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattc tgattaacag
     2221 ttggtgaatt atctaaatca ttagtaattg cattagaaga ctcttttgta gccatcggtg
     2281 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2341 atagtaccga gcaagtccct acctttaatt tacgaatact gaatacctca ttaggaacaa
     2401 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     2461 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     2521 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     2581 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagacgg
     2641 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     2701 atcgatttgt cctattctta tttcatttta ctatatctac aacctcaaag cagggttttg
     2761 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     2821 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     2881 aaattataaa tgaaagaaca aataccttgt catacaagca ttcgccaggg atatttacat
     2941 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3001 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3061 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3121 gatgtatagc aagcatcact aaacatatag aatatttgta ttattataag atcaatatgc
     3181 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3241 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3301 tctttcaaaa aatagggtga attgaaaact agaacaagac actagatttt ctaaatgatg
     3361 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     3421 tctcacaaga aaggaaaatc ctataaaaat tctctctctg aggagaaaga ggcctcaact
     3481 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     3541 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     3601 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     3661 tgaagaggga gggtaatttc attcttaaag aaggcatagg ccttaggata gttcgtcata
     3721 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     3781 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     3841 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     3901 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     3961 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4021 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4081 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4141 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4201 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4261 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4321 ttttgccact tgcttgaagc agtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4381 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     4441 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     4501 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagctgtata ggtcatggct
     4561 ggaacgatga cttcatcacc aggtcccact tccaaaacgc gtaaaatcaa ctccagagcg
     4621 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     4681 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     4741 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     4801 gatttgctcc ttttatctgt actcattttc ttatgactac tttattttag tacctcaaac
     4861 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     4921 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     4981 ttctccgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5041 gtaattcctg cttgcaagag caaggttgcc atcatttcag ggctatactg ctctgtataa
     5101 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5161 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5221 tcgttagcag aagtcaccag acttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5281 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5341 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggttagaacc
     5401 agtaagacca aggccaaaaa ccagtccaag caacgcttga aaatcagcga acccttcctt
     5461 ttagagacaa gatggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     5521 tcccatttca gcatactgtt ctcctttgtt tttattatac tatttgtcaa catttttcat
     5581 tataccacaa aatggaaaag gcggtgaaag aaatctgtaa tttgaaggat ttccttctag
     5641 tactcaatga aaatcaaagt acagctttga gattgcagat aaagctgaca tggtttaaag
     5701 agattttcaa agagtatcgg ccatggcccc tgcctgcaaa ctatacatct tgtgataggt
     5761 tcctcccaga gtcaagagtt cctcatgggt tccactctcg ataatgcgtc ccttatccaa
     5821 gacatagatg cagttggcgt cttgaatagt agaaaggcgg tgagcgatag caatagttgt
     5881 tcggccctgt ctcatcttcg ccagagaagc ttgaaccaag ctttctgttt cagagtcaat
     5941 attggctgtc gcttcatcca aaatcaggat tttaggctgg ctggcgactg ttctagcaaa
     6001 ggcaagaagc tggcgctgcc cagtagagaa gctcgaacca cgctcggaaa caggggagtc
     6061 gtacccctga ggaagttctt gaataaagga atctgcatcc acaaaggctg ccgcagcctg
     6121 aacctgatca tcactgattt cttggtacat ggcgatattg gacttaatag ttccatgata
     6181 gaggaagggt tcctgcaaga ccaaaccgat gttttttctc agctcttctt gactgaaatc
     6241 cctgatatcc acatcatcca agagaactct ccctgactgg aattcataaa agcgcatgag
     6301 gacattgata atagacgatt tccctgaacc tgtatgacct acaaaggcaa tggtttcacc
     6361 cttattaaca gagaaagaaa tgtcatccag aatcggatgt ttaccgtcat atgagaaaca
     6421 cacatgttca aaacggatat tgccttcttg gactttggct tgcccatttt cttgaagagg
     6481 ttcataggtc ctctcgtcta tcagggcaaa gacacgacct gcagaaacca tagccgtttg
     6541 cagagttgaa aagttttgcg tcacctcaat caaggggtca aaaaggcggt tgatgtactg
     6601 gataaaggca tacatggtcc cgaccgttat cccgatagaa aaaccacggt agccaaagta
     6661 ggccatcaag actgcatagc ctagaagttt cagcaaactc atggcaggtc tcaaaaagag
     6721 ggcatccaag gctacagaac ggttggcgta gaccaagtgt tcttggttga tttcatcaaa
     6781 ttctgcctgc aggcgcttct cttgattaaa agcctgaata atcctgattc cctcgatatt
     6841 ctctgccagc ttactattga tatctgacaa gagacttctg gttttctcaa tgattttcac
     6901 tgattttttc cgatagagat tgaccaaaag gaaaatcaag gggagaaaga gcaagactaa
     6961 tgctgtcaaa cgaaaatcca ataccaacat ggtataaagg gttgtcagaa agatgaaaac
     7021 tgctgagata aagctggata aaatccccga aaacatatca ctgatagtct cggtgtcatt
     7081 tgtcaaacga gagacgatag agcctgctgg cgtcttgtca aagtaagaca tgcccagttt
     7141 ctccatattg gcaaaggcat cccgacgaat atccctaaca atactgtaag acacgcgcgc
     7201 aaagagaaga ttgcctacat actgaactac agtttgtagg atgtagagac catagtagac
     7261 cagcaaaacg gtaacggcta gttggttaag attgctgaga tactggtcga taaagtggga
     7321 agccacgagg ggtatgacac ttttaatgac cgtcgtcgct aggagaaaac tgagtgccaa
     7381 aaaggtcagg agtctataag gcttgagata agacatcaag cgcttcaata cagcccattg
     7441 ttcttgttta ttctgcatct tcttctcctt tcatttctaa ctgctgagac tggtaggttt
     7501 gggcatacca gccatccatc gctagcaagt cttcgtgcgt gcctcgttcg ataatttgac
     7561 cattttgtag aactaaaata aaatctgcat ggacaacagc actgaggcga tgggcagtga
     7621 taatggttgt cttgtccttt cgcgtctcct tgaggttgtc gataatcgca tactctgtct
     7681 tggcatctac ggcggataag gaatcatcca aaatcaagat atcagggtct aaaatcatag
     7741 cccgactcat agccaaccgt tgcttttgac caccagaaag actgactcct ttttcaccaa
     7801 tcagcgtatc aaatccttga ggcatgtcta caatatcttg gtaaactcgg gctagcttag
     7861 tagcttcctc gaccgctgaa aggggcaagt taggattgcc aaagcggata ttgtctagga
     7921 ttgaagttgc aaagagaaac tggtcctgag gaacatagcc catgagactg cgaaggtctg
     7981 tcagacgata gtcccgaata tcgtgaccgt ttagataaat ggcaccctta tccacatcgt
     8041 attcacgcaa gaggagcttg attaaggacg ttttcccaga gcctgtctgc ccaaccaagc
     8101 ccagtgtttg cccttttgcc aaactaaagt gaatatccgt cagtgtttcc tcattttcaa
     8161 aagcaaagct gtcaatggca tactccaaac gcccattttc aataccatcc agaggaaact
     8221 cagggtcttg tacaggagat tcctgagaca aaagattttc aatccgctgg taagaaacct
     8281 tccctcgctg agtagtatta aagaggaagc cgatggccat aagaggccag accagcatat
     8341 ccaaatagct gataaaggtg actagattcc caactgtaat ctgcccttcc tgaaccatca
     8401 aggagccaac caaaagcgtt aaaacatagg acgaaccaac aaacacgaga accatagggt
     8461 caaagagact atcatatttc atggtttgca ggttcttttg gaaggttaat tcattgactg
     8521 cctgaaaaga cttcaactcg tctgcctgat aaccgaaaga cttggtcact ttgatacctg
     8581 atacggactc ctgtaccttg ttattgagtt cagaaaaagc agcttgggat tcgccaaagg
     8641 ccttatgagt ctttctccct aggcgactag tcgcataggc catgaaaggt agggggagaa
     8701 tggcaacaag agtcatctgc catgagatgc taaagagcat ggtcaacaaa gtcaccagag
     8761 ccgtgataga ggcatccacc gcagacatga caccgccacc tgctaaacga gtcaaggcat
     8821 tgatatcatt ggttgcgtgt gccatcagat cacccgtccg ataggtttga taaaaggctg
     8881 atgacatttt tgtgaaatgc ttaaacaagc gagaccgcat gatctgtccc aagcaataag
     8941 aggtcccaag gatatacata cgccacacat agcgcaaata gtacatacca aaggctgcaa
     9001 gtagcaagta aaataggcta agaaggaggt cctgctgggt taattgcccc gatgtgatgg
     9061 catcaatgac ccgccccata accataggag gaatgagatt gagaacggaa accaagacca
     9121 gggccacaat cccgactaga taacggcgtt tttctaactt gaaaaaccac caaagttttt
     9181 gaataatgga cataaaatcc ctttctgatt gcaaatggaa acctgaggcc aatactcaat
     9241 gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgc tcaaagcact gctttgaggt
     9301 tgtagataga actgacgaag tcagtaacct acatacggca aggcgacgtt gacgcggttt
     9361 gaagagattt tcgaagagta caagacccca ggtttttctt tttcataagt tacgactgta
     9421 acagcaccct tgtcatattc agcaataaag atattggcta cattgtcatg cccttgttta
     9481 ctgaggttat caagcaacca ctcttcgcta cgaccaatcg attccaagac atctacttga
     9541 atcacaccgt cagtcacaac tggatactta ggattttcat ctcccatttg cacaacgata
     9601 agttgcccat tttgctcttg cacagctcgt ttgacttgct tcatctggaa aatcccttgg
     9661 ctacgaagtt tgagggctac atccgatgca gacaaaccaa ctgaacgaca ggcttctggg
     9721 tcaatattcc catttttgat aaggagagtt ggcttaccat caatcaaacg tttcacaaag
     9781 tgaacattgt tgttgagcca tttgagagtc aagaccagtt tgattaaaat ttcgatataa
     9841 ttaagtgtca tttgttcaca tccaccagtt caattgcgtc tgtcttatac aattcgactt
     9901 tctctaacag gtacttgtct ggctcacttc cgtttagggc acgataatag cgatctccca
     9961 ccttgataag tgcgccatct gtgtttgtgg aagtattaac atagacttct gacttgtcta
    10021 ctcccaaatc tttggaaaca acctcgatga aatgaagtga agtttgaaat ttattgttag
    10081 aaacttgatt gttttgataa gtcgtgatgc tgaccaaaag cagagctaaa taaggccaga
    10141 gctgaaatca tgaccaactc acgaaattcg gttccctttt tatcatggta tgccttgaaa
    10201 gcaaaaaaaa ctgtcacagc taatagaaca atcccaaagc caaccatgat accattttgc
    10261 tgaccgattt ggctgagtac atagtcataa gagtagaatt tcatatattt tcactccctt
    10321 tcataaaatc attcttaatt ataaacgaaa gagagtaatt tttcaaacca tacgttgggg
    10381 aaatagatct ttttttggta taataaaatc tataatctga atgaaaaagg taactttatg
    10441 aaacttatct catggaatat tgattcccta aacgctgccc taactagtga ctcagctcgt
    10501 gccaaattgt cccaagaagt cctacaaacc ttggtcgctg aaaatgctga tatcattgct
    10561 atccaagaaa ccaagctttc tgccaaagga cctacaaaga aacacgtgga aattttagaa
    10621 gaactcttcc caggctacga aaacacatgg cgctcttccc aagagcctgc ccgtaaaggc
    10681 tatgctggaa ccatgttcct ttataagaaa gaacttacgc ctacgatcag ttttccagaa
    10741 atcggtgccc cttctaccat ggacttggaa ggccgtatca tcactctaga atttgatgca
    10801 tttttcgtaa cccaagttta cactccaaac gctggtgacg gtctcaaacg cttggaagaa
    10861 cgccaagtct gggatgttaa atatgctgag tatttggctg aactagacaa agaaaaacca
    10921 gtccttgcga ccggtgacta caacgtagcc cacaatgaaa tcgaccttgc aaatcctgct
    10981 agcaaccgcc gttcacctgg atttactgac gaggaacgtg ctggatttac caaccttttg
    11041 gcaactggat ttacagacac cttccgccat gttcatggcg atgttcctga acgctacact
    11101 tggtgggcac aacgcagcaa aacttctaaa atcaacaata caggctggag aatcgactac
    11161 tggctcacaa gtaaccgtat cgctgacaag gtcactaaat ctgatatgat tgactcaggt
    11221 gctcgccaag accatacacc gattgtcttg gaaattgact tgtaaggatt ttctatatgg
    11281 actacaatgc ggtcattccc gagtttcttg tatcgaatat cgaacagtcc cggtccttct
    11341 actgtggttt actgggtttt aggattgaat actaacgtcc agaagaaaac tttctctttc
    11401 tcttgaagag tgtcaactaa tgttagagga gggaacaaag gatcaactag ctgaactgac
    11461 ctaccccttt ggtcgtggag tcaatctctc ctttggcata aaggatgttc caaaactcta
    11521 tcaaaaagtg atggaggcaa actatcctat ttatcgtctc ttgaccaaaa gaaagtttcg
    11581 tgtcagtgat ccctatatct atcctcataa atttgcagtt ttggatccag atggctattt
    11641 tttaagattt agcgagtaga ataataaaaa ttgggaaaag tctttaaagt tagaaaaagg
    11701 catattgtca ggtgtctaaa aacttgatag tatgcctttt atgatggaaa aatcttctaa
    11761 tactcttcga aaatctcttc aagccacgtc aacgtcgcct taccgtaggt atatgatact
    11821 gactctgtca attctatcca caacctcaaa acagtgtttt gaggttgtgg atagcttcct
    11881 agtttgctct ttgattttca tttagtataa atgttagctt acaatgaagt ttttgttcac
    11941 cctctcttct ttttgttcgc tttttaaacc aaaacactaa caaaatagtt gatttctaaa
    12001 gttatttagt gtaaaataaa aacattggct caagcctatt taaaattgaa tatcgtttta
    12061 cttgtttatg tcgtgaattg gcacgacgtt tctacaaggt gccggaacac ctaacaataa
    12121 gtaagtcagc agtgagatat ggccgttttt gccatgtcta tttaggggac ttacttagag
    12181 attaagtagg tcttttttga atatttttaa tatttccctt aattagtgcg gacgggaggt
    12241 gaaattatcc tgtgaataat ttcaggaatc cagggaattt catccctaat ttttgagccc
    12301 ctagctcttt catttctagg cttaggctaa aatagttccc cgaactattt tactctcaaa
    12361 aatcccgtca tagacaataa caagattatt gtctatgata ccactacaac gggaaatatt
    12421 tgataagact cgcttcgctc gtaatagttt tatcaaatat atagtattag caaaagggat
    12481 cactatagaa atatttaaac aacaagtaaa ttaactttta gactttagga ggtcttatga
    12541 aattattaga agagcgcatc ctcaaggatg ggcatatctt gggtgataac atcctcaagg
    12601 tagattcctt tttaacccac caagttgact ttagcttgat gcgagagatt ggtaaggttt
    12661 ttgcggaaaa atttgctgct actggcatta ccaaggtcgt aaccattgaa gcgtcgggta
    12721 ttgccccagc cgtttttaca gctgaagcct taaacgttcc catgattttc gccaaaaaag
    12781 ctaagaacat caccatgaac gaaggcatct taactgctca agtctactcc tttaccaagc
    12841 aggtgaccag cactgtttct atcgctggaa aattcctctc accagaggac aaggttttga
    12901 ttatcgacga tttccttgct aatggccaag ctgctaaagg cttgattcaa atcatcgaac
    12961 aggccggtgc cacagtccaa gctatcggta tcgtgattga gaaatccttc caagatggcc
    13021 gtgatttgct tgaaaaagca ggctaccctg tcctatcact tgctcgcttg gatcgttttg
    13081 aaaatggtca ggtcgtattt aaggaggcag atctctaatg caaactcaag aaaaacactc
    13141 gcaagcagcc gttctgggct tgcagcactt actagccatg tactcaggat ctatcctggt
    13201 tcccatcatg attgcgacag cccttggcta ttcagctgag cagttgacct acctgatttc
    13261 tacagatatc ttcatgtgtg gggtggcaac cttcctccaa ctccaactca acaaatactt
    13321 tgggattgga ctcccagtcg ttcttggagt tgcattccag tcggtcgctc ccttgattat
    13381 gattgggcaa agccatggta gtggcgctat gtttggtgcc cttatcgcat ctgggattta
    13441 cgtggttctt gtttcaggca tcttctcaaa agtagccaat ctcttcccat ctatcgtaac
    13501 aggatctgtt attaccacga ttggtttaac cttgatccct gtcgctattg gaaatatggg
    13561 aaataacgtt ccagagccaa ctggtcaaag tctcttgctt gcagctatta ctgttctgat
    13621 tatcctcttg atcaacatct ttaccaaagg atttatcaag tctatctcta ttttgattgg
    13681 tctggttgtt ggaactgcca ttgctgctac tatgggcttg gtggacttct ctcctgttgc
    13741 ggtagctcca cttgtccatg tcccaactcc actctacttt gggatgccaa cctttgaaat
    13801 ctcatctatt gtcatgatgt gtatcatcgc aacggtgtct atggttgagt caactggtgt
    13861 ttatctagcc ttgtctgata tcacaaaaga tccaatcgac agcacgcgcc ttcgcaacgg
    13921 ttaccgcgca gaaggtttgg ccgtacttct cggaggaatc tttaacacct tcccttacac
    13981 cggattttca caaaacgttg gtttggttaa attgtcaggc atcaaaaaac gcctgccaat
    14041 ctactacgca gctggtttcc tggttctcct tggactgctt cctaagtttg gcgcccttgc
    14101 ccaaatcatt ccaagctccg tcctcggtgg tgccatgctg gtaatgtttg gttttgtatc
    14161 aattcaaggg atgcaaatcc tcgcccgtgt tgactttgct aacaatgaac acaacttcct
    14221 tatcgcagct gtttcaatcg ctgcaggtgt cggtctcaac aacagtaatc tctttgtcag
    14281 catgccgaca gccttccaaa tgttcttctc aaacggaatc gtcgtagcca gcctactcgc
    14341 tattgtcctc aatgccgtat taaatcataa aaagaaataa gaaaaagagg tgcgagcctc
    14401 ttttttgttg acaaaataaa aacatctacc tattcatata tgctagtgtc atagtcctga
    14461 aaatcatctg catcaagaac aatttcacaa ctcttatact tttctcttac aagtcgttcg
    14521 gcttcatctg gattttcagc ctctatactt actaaacgtg ataaagtttc tgtaatttct
    14581 actgtatact ttttcagttt tagattgctt tccaataatt cacctattaa caataatcta
    14641 tgataggagc tatgtagcca ctctggcaat ttatctccta cttcccaccc atatttttcc
    14701 ttcatcaaag ctagttgttt ttcgtcacca aatttcatat tttcagataa ccatctcaca
    14761 caatcgggat ctgataaggt acagacgatt aaacttaggt tatcgtaacg gctttcagtt
    14821 tcataatcag gccagatgac ttttaagaaa tcatacacct cttctgatgc aacaagttgt
    14881 ttcgttttca taatttccga tactttcctc tacctttaaa ttctattatt tctttgtctc
    14941 ttaatatttg aagctgttgc ctaatctttt ctttgatatg attgttctta acaaagatat
    15001 tttttaggtc actttcaaaa cgatacatat cttcaagggt aaattctgaa ccctctatct
    15061 tatctataca atttagaatt tctattgtcc aacctcttga tgacagagag ctcttcctta
    15121 aaaataaacc ttgcttaaat tcttttgtaa ctttttctgg atctctaact tgtccatctt
    15181 gcacaagaaa tatccttcct ttagaaggta cttgtgataa atcaatgtta caaccaatcc
    15241 aacctgctcg tctagcagtt ggtgcaagtg gttttctttg aataatcgat ttcggtgtaa
    15301 caaattgctt cggaaggaca agaaagttat ttacctcaaa attttttgtg taagttaaaa
    15361 aaaagaaatt aggattatta tctgcctgca cacgcttcat catcgttgca taagcaccat
    15421 cattgattgt tgatgaaaaa tttccttttt tgctctttag ttcaaactcc tcactacaat
    15481 gattacagta aaaatctgct acaggccgat tattttcaaa atgatttaag ggattgttcc
    15541 cacaattagg gtaataagac tgacgataaa cccaatcctc cgttaagata cgtgcctttt
    15601 ggctattact tttataggtt tctactaatt ctaaattaaa gtgtaattcc atttaaaaat
    15661 tcctcactaa tatgagaact cactcgatat aagcaattaa aatctactat aactagtata
    15721 ccacatatat gtacctatta catttgtatt tcatcactct cttttatatt tccttctaac
    15781 atatctcata aattaaaaat gagtgagata aatttatccc actcaccttt ctttatatcc
    15841 ttacccgtct ttcctcagac ctttggccta tgacaaacat ggtaaaggtt gctttgcaga
    15901 catttctgcc ctcttgattg gtgatatcca catccatcac acaggttgta cggccttgat
    15961 ggacacattc tcctttaatg gtcaatacat cgtcgagttt tcctgcctta aggtagttga
    16021 tagaggattg gagtgtcacc ccatcaagtc ccagcgagat aaccaccaaa ccactgattt
    16081 ggtcacatag cgtgaataga tagccaccat gggcattgcc atagtagttg agcgacgagt
    16141 tcactacttt ggtcgtcacc acaacgtgac catctctcat tttttcaatt tcgtaatttt
    16201 caaaggcaga tatagcgtca aaatgaaagt ctttcatcgt ttcctcctga tatttcaaac
    16261 gacactatga tactactttt tataggactg tgcaaggaga aagctcctag tctagtaaaa
    16321 ttccgacatg ttccacaaag cgcataaagg ctgtctgccc ttgttctgtc tgcttgtaga
    16381 ctcctgcatc ctcaagtaca cgcgcaaaga tagcacccac agagtccttg acgattgcaa
    16441 gggctttttc tttatccgtt aggtctggat gttgggattt gagttggtct gcccactcct
    16501 gatgataatc ggcaactgta acagcttctc ctacaagata gctcgcgact tgctccactt
    16561 cttctttcag acgtggtggc aagattgcca agcccatgac ctcaatcaag ccgatatttt
    16621 ccttcttgat atgttggaca tccttgtggg gatgatagat accatcagga tactctgctg
    16681 aagtctgatt gtctcgcaag accaagtcca actcaaactg tccatcgcgt ttgcgggcaa
    16741 tgggtgtgat agtgtgatgc ggtgtcctgt ctgtctctgc caaaatctgc actgcaggat
    16801 ctgaatactg gcgccattcc tgcaaaatct tatcagccaa attgatcaaa tcctctttgg
    16861 aatccgaagt caaacgtagg acagacatgg gccacttgac aattccagcc ttgacctgct
    16921 caaaaccagc aaatcggaag gccttttgca agggagccaa ttccatagga aatacgtgac
    16981 ggcctccctg ataatgatca tgagttagaa tagagccccc cacaatcggc aggtcggcat
    17041 tagatccagc aaaatatcct ggaaactggt ctacgatagc caacagacgt tcaaaactct
    17101 gacgactaat ggccatggga cgatgctggc catctaaaaa gatacaatgc tcattaaagt
    17161 aagcataggg cgaatactgg aaaccccatt cctgaccaac catttcaaaa cggataatac
    17221 ggtgattgct acgagctggg tggttaactc gaccatggta gccctcattc tctagacaaa
    17281 gctgacactg aggataatta ctagcttgca ccaacttggc tgccacaatc tctttcggat
    17341 ccttttcagg cttagagaga ttgatggtaa tttcaagttc tccataatca gatggaacac
    17401 gataagcgat atttttagca atggccttga gtttgatgta gtcatttttc tgactgagtt
    17461 gataaaaatc ctctatcgct tgctcaggat agtggacata ggtttcccag aagtcacgat
    17521 tgacctgact cggacaagga gtcaccaagt ccatcagttc agtaccaagg atttcacgcg
    17581 cagtctgact atcctcaatc gtctctaatc gaacggcttc ctcaactagc tggtccttga
    17641 ggtcaatcaa tttatccaga ttggtctcaa cttccaaaac accttctccc actcgtgcca
    17701 aaacacgatt ggtcaggtag attcgatcca tttcctcaaa tgaactttca gaaatgacat
    17761 gtgttacaaa tttatctact aaggtcacca tagagcctcc ttttgactag tcaaggacgt
    17821 gagtgccacc tgcaacttca gcgatataga agcttggagc gtatccaact acttcctcgt
    17881 agtgtttgcc tacagtttcc ttaaaggcct caacagtatc tttttgaacc aaggcaatgg
    17941 cacagccacc aaaaccagcc cctgtcatac gagcaccgag aactccttct tgtgcccaag
    18001 ctgtgtgaac aagagtatcc aattccaaac cagttacttc ataatcatgc tccagagaaa
    18061 cgtgtgacgc attcatcaaa cgaccaaatg tttccaaatc acctgcttga agggctgctt
    18121 gagctttaag ggtacgttgg ttttcaagca cagcatggcg agcacgtttc aaacgatttt
    18181 catctttaat caaatagcta tattggtcaa cggcccactc gtccaattca cccagggtct
    18241 gaatatccaa ggcaacttgc aattcttcca ctgctttttc acactcagca cgacgttcat
    18301 tgtatttaga gtccgccaat tcacggcgtt tgttggtgtt catgataaca acgacattgt
    18361 ccttcaaatc aagtggcacc aaatcatact ctaaggtgtt ggtatcaagg taaatagcac
    18421 gttgatcggc ccccatacca atagcaaact ggtccatgat accagagttg actccgataa
    18481 agttgttttc tgtttgtttt ccgattttaa ccaaatcgag acgctctaat tttaaatcaa
    18541 agagatgctc tgccacgact cctgtcaaga gctccaagga tgctgaagaa gacaagccag
    18601 caccatttgg gatattccca taaacataaa aatcaaaacc tttgtcaatc acgtgcccag
    18661 cttcttgcaa gaaatgaagg acaccttttg gataattggt ccagttgtgc tctttttcaa
    18721 acttgaggtc agcgagaggc acttcgataa tgcccttgtc ctcaaagtta gctgagtaga
    18781 aacgcaagac ttggtcgtca cgcttacgag ctgcaccgta agttcccaag gaaatagcag
    18841 caggaaaaac gtgcccaccg ttgtagtctg tgtgttcacc aatcaaatta atacggcctg
    18901 gtgaaaagaa ggtttggtct gcttcttgac caaaaacagc aagaaagtct ttgcgaagga
    18961 cttcagtagt aagatgttgt gccatatgaa ttctcctttg actgtccgtt aagccatctt
    19021 aacgtgtaat cgttttcttt ctattgtatc caaggaattt cccaaggtca atccttttta
    19081 ctaaaatttt actaaaatat cagtaaaaag aagaaaaata tgatatacta acctaatcaa
    19141 ggaggattta tggctacctt aaaagacatt gcacagctag cctctgtctc aatcgcgacc
    19201 gtatcccgtg tcctcaaccg cgaccagagc ctatctgtta cagaagaaac cagacaccgt
    19261 attttaaccg ttgctgaaga gctaggctac accaaacacc tcaagacagg cgagtcccac
    19321 aagcccaagc aaaagattgc cattatccaa tgggtcagcg aacaagggga gctagacgac
    19381 ctctactact accagattcg cctaggaata gaaaaaagag cccaagagtt ggactatgat
    19441 atcttgcgct attttaatga ccatcctttt accctaagcg aggaagtgat tgggattctc
    19501 tgcatcggaa aatttagccg agctcagatt tctgcctttg aagaatacca aaagcccctg
    19561 gtctttctag acagtgatac actttccctg gggcatactt gtattattac ggatttttac
    19621 actgctatga aacaggttgt cgattatttc ctcagtcaag ggatggaccg catcgggatt
    19681 ctaacagggc ttgaggaaac aacagaccaa gaagaaatca ttcaggacaa gcgtctagaa
    19741 aacttcaaaa actacagtca agcgagggga atctatcatg atgaactggt ctttcaagga
    19801 agatttactg cccagtctgg ctatgactta atgaaggagg ccattcagag cttgggagac
    19861 caacttccgc cagcattttt cgcagccagc gatagtttag ctatcggtgc cctccgtgcc
    19921 ctccaagaag ctggaatcag cctgccagat cgcgtcagcc tcatttcatt caacgacacc
    19981 agtctgacca aacaggtcta tcctcccctc tctagtatta cagtttatac tgaagaaatg
    20041 gggcgagcag gtatggatat tcttaacaag gaagtcctcc acggtcgcaa aattcctagc
    20101 ctgaccatgc tgggaaccag actgacatta agagaaagta ccctaaatca agaataggat
    20161 aacataaaaa acgaatagag ttctaaaact cctattcgtt ttttattcga ttacaatcat
    20221 agacttaatt gtcttacgtt catccatatc tttataggct tggtcgatat cttccagttt
    20281 ataacttgaa gtaaagacgc gacctggatt gatatcacca tcaaggacgg cttttagtaa
    20341 aaattgctta tcgtatgttg tagcagaagc tgccccacct gctacagaga tattttgcat
    20401 aaatgtcgaa ccaagagcac gattattata gtgtgggact cctacaaagc ccatacgccc
    20461 tccattatga agaacaccta gcgcctgttc tatagcagcc tccgtaccaa cacattcaag
    20521 tgctgcgtct gctcctccgc cgaggatttc acgcaccttg gtaattcctt cttgaccacg
    20581 ttctgcaaca acagctgtcg cacctgactc catagccatc ttttgacggt cttcatgacg
    20641 gctcataagg ataatttgtg atgctccacg catcttagcc gcgatgacag cacattgacc
    20701 aacagcccca tcaccgataa caacaacctt gtcccctttt tgaacatttg caacacgcgc
    20761 tgcatgatag cctgtcggca tgacatctgc aagagtcaaa agggacttga gcatcccttc
    20821 tgtataatca gaaggttgac cagggatttt aaccagcgcc cagtttgcat agtggaagcg
    20881 aatatattct gcctgaaaat caccccccaa attattacca atatgattgt cgcaagaacc
    20941 gtcaaatcca gcaagacagg catcacactc accacatcca tgtgtaaaag ggacaatcac
    21001 aaaatcacct ggtttcaccg tcgtaatggc ttccccagct tcttcaacaa tcccaatcgc
    21061 ttcgtgtcca ctatttttat gtccagcttt cgtttctgga ttacggtacc tccataaatc
    21121 tgaaccacaa acgcacgcac gaaccacacg aataatcaca tcatccgctt ctattatttg
    21181 cggacgttca atgctagcaa gtccaacctg acctgccttt gtatatactg ctgatttcat
    21241 ttaaaatttt ccttccttat aaagtttaat tttgagattt aaacgattta aagctgtctg
    21301 tagctgagac aagcgctcct ctaatttttg cttttcctct tctaaaatac caagcctctc
    21361 ctctctcgtt tcatctccct tttggtagag cgacatatag tcaactaaac tatctacaga
    21421 gacacccgcc gaacgaaaac acttaataaa ttccagcgct tcgatatcct gatcttgaaa
    21481 atcacgaatc ccagtagcag tacgagtaat cggtggcaca agaccaaccc gttcataata
    21541 ccgaatcgta tccgctgaaa ttcccaacaa atcactggca gatttaatat tcacacgcta
    21601 acctcctctc atttcattca ctgaattcac gctattctaa ctcacttatc ttattatata
    21661 actttgagtt gactccaagt caagcatttt gtatctaatc gaaaaatttt tatcattaac
    21721 aatcatatat ctggagttta tacaatgctc ttctcttacc aatttttgaa atatttaaat
    21781 aataaagaaa ttactctatt ccaaataaga tagtacccaa gtatttttca cttttttcta
    21841 atgttgatgc tcataactcc gttccaagtc acacaccttt cgcttatggg tttggtgagt
    21901 ttctaggtca gcatcaattt caatggtaat attttgaaaa ccacaatctt ttaggaaaat
    21961 tcgaatagac tctttacaag tttccatatg ttccatttct tttagacaaa catgtacaat
    22021 ggcatttttt tccaaagcat ccatagtcca gagattaagc tgattaaggc tggccacatt
    22081 gtccaatcgc tccaggccac tctttacttg cttgatatca agaccttctg gcacagcatc
    22141 caagaaaatc ttgagtgtag accaaaaacg tggaagggct tttgaaagaa taaagaaaga
    22201 aatgacaagg gacaaaagag gatctaggat ataccagtcc gtaaatcgaa gaacaatcgc
    22261 catcaggata acagctaccc accctagcgt atcttccaga aaatgcaaac tcagaataga
    22321 ctcattcttt gtctttccct taccaaccac cagactcgct aacagattga tagtaatcgc
    22381 aataattcct aaccagagaa tcccctcatc attgactggt tgcggatgca aaatcttcgt
    22441 gacattttcc aaaatgacta gaacagagcc cgttacgaga atcacagctg ttaccaaggc
    22501 tcctagcagg ctaaaccgct tatagcccaa ggtgtactga ttgtcttctt cacgattgga
    22561 gattgtttct agaaaagctg atattccaat tgcaatcgca tctcccaagt catgcacaga
    22621 gtcagcaaga acagcgctag aaccaaatac tccacctgca ataaactcaa caatggcata
    22681 agtcaaattt aagaaaaaag ccacccaaac agcatatttt gccttcatat ttctcattcc
    22741 tttgttataa tagatttatg aacaccttgt tcattatcat tatccactaa aactcaaaga
    22801 aaggatagaa gcaaaacgtc agctttattc agttctgaac aatttgcctt aagtgtccat
    22861 atgactaaca ttgaccgccg tatcagcaaa accaaaaaag ccatctatca agcttttata
    22921 caacttttga atgctaaggg ctacgaggcc actactgttc aggatatcat tgatctcgca
    22981 gatgtgggaa gatccacctt ttactgtcac tatgaaagta aggagcttct tctggaccag
    23041 ctctgccgct acctcttcca tcatcttttt gaaagagagc aagccatttc aaccgaggac
    23101 tacctcgccc acctctttct ccattttcag aaaaaccaag accatatcac cagtctgcta
    23161 ttttccaaaa atgactactt cctccgtcaa ctccataaag agctagaaca ccatgtctat
    23221 tccgtgctag ctgataattt aaaagaagcc caccctaata tgcctacttc ttacctccaa
    23281 cacttggtcg tgtccaactt tatcgagaca ttgacctggt ggctcaaaaa aggtcaagat
    23341 ttcataggcc aggaagttgt ccaattttat ctagaccttc tcattcctaa aaattgaata
    23401 tagagtaaag ctcagttgtc ttatttctag gttactgagt tttttatctt ttcaacaaca
    23461 aaagaggacc cgccgatcct ctttttcata ctataaatcc ttgattatca actatatctg
    23521 ttttaatcga aatctcaaaa cagcactttc aaacatcttt tcctagttaa gtaaatcagt
    23581 attctgctta gctgccttgc tccattgata ccaaccaact agactgttaa tgagataaat
    23641 tagatatttc ccttgaattt gcaggctttc tccccaccag agatagattg aaaaaacatt
    23701 ggtagccgcc cagaatatcc actgttcacg gtaaacagct gtcatgagga tttgccctac
    23761 cccattggtt gcatctgtga ttgaatcacg atagggacga ttggcaccaa tagactgata
    23821 aatgaagcca aaggccaacc accaaagcac actaatggaa agatactttg tccagccctt
    23881 gccgtccagt ttacgcgcga caaactcctg cttttccttc ttaaactgtg cctgataaat
    23941 ccaaactaga agtccaattg gctgcatgac tgtgaagtaa agtgtcgtca gcacctcacc
    24001 ataaaagcct ttctgtaggg ccaaaataag gtaaataaca gagttaatca agccaaaaag
    24061 ataattactt gctcgacctt ccgatacaaa gattacacag ataatccctg tcaagctaca
    24121 aatcatccca atccagtcaa caatacgatg ttcgtaaacc aactccagcc agagaggaaa
    24181 acttcctaaa accagcaaat aaatccactg ggcaaaacta cgatgggcaa agaggtcatc
    24241 ccagatagcc ttcatagttc ctgaaaatcc taaatcagcc atagccgcaa ccatacgacg
    24301 gtaaccacct gacatttcac ctagggttgt tttgatattt tcaattttct tttgcaaata
    24361 agtatgcatc atttctcctt ttgtttttaa agagccgtgt ctggatagac tttcggacgc
    24421 aacgctctat tagataatga actgcctata cacaagattt ctaaccttag tcgacatgag
    24481 ctaaaacctc ttatttgtta agtagttcac aaaatattat acacctattt tatgaatagt
    24541 caactgtctt tacagtaaaa ttttagaaaa tcatgaaaat tttctctttc tttccatttt
    24601 aagtgacatt cagtcattct cacatcaaaa aagcccagac gaaattgtct gagcattctt
    24661 ttatctagtc gtttaaggaa gttgagttca gtatgtttaa agtctctgtc ccatcatttc
    24721 ttcaacaaac cttgttcttg gagaaactcc ttggctactt gctttgctga cttgccttca
    24781 acaccgactt ggtagttgag ctggctcatc tggctttctg taatcttacc agccaatgta
    24841 ttaagaactc tttccaactc tgggtgtttc ttgagaagag cttctttcat gagtggagcc
    24901 ccttgataag gtgggaagag ttgcttgtca tcttccaaga cctgtaaatc ataacgctcc
    24961 aattccgcat cagtcgaata ggcatccgtg atttgaatat cccctgactg aattgcctga
    25021 taacgaagag ctggctgcat agtcgccaca ttgagattga gaccatacat tgattgcaag
    25081 cccttatttc catcttcacg gtcgttaaac tcaagcgtaa agcctgcctt cagctgccct
    25141 tccacttttt tcaaatccga aatggtcttc aagccatatt cttgcgcaat ctttttcgga
    25201 acagctacag cataggtatt ttgataagac ataggtttga gataggctag atgatcctgc
    25261 ttggcaatgc tatcacgcgc cacttgataa acctgctctg gctcatgact caccttgggt
    25321 gatggttgaa gcaaactttc agtcaccgta ccggtaaatt caggataaat gtcaatatca
    25381 ccttttttca gagcttcata aaggaaactt gtcgtcccaa aattcggttt aacagtcgca
    25441 gtcatgctgg tattttcttc aatcagcaat ttatacatat tagccaaaat ttctggttct
    25501 gggcctattt tcccagcaat aatcaagttt tccttctctt tttgagccaa aagggctgga
    25561 ctataagaca gacccagtaa taaagccacc aaggcaaaac cagagaaaat cgtccgcaat
    25621 ttcgcttttt ccattacttt tagtaggaag ttaaaggcaa tagctagcac tgcagaagaa
    25681 agggccccaa tcaaaatcaa actggcatta ttacggtcaa ttcccaacag gataaaggaa
    25741 cccagtcccc ctgccccaat caaggtcgcc aaggtagccg taccgataat caagaccgct
    25801 gccgtccgaa ttccagacat gataacaggc atggcaagtg gaatttcaaa cttcttgaga
    25861 cgctcccatc tggtcatccc aaaggcaatc ccagcctctt gaagactcgg atcaattccc
    25921 ttcagcccag taatagtatt ttgtaaaatc ggaaaaatcg cataaatcac tagagctgtc
    25981 aatgccggta aagtcccaat tcccatcaag ggaataaaga gtcccaacaa ggccagagac
    26041 gggatggtct ggaaaatccc tgcaatctgt aagacccaat ccgccaactt ctcatgatag
    26101 cgaagaaaaa cagccaaggg aatcgcaagc aaaatagcta gtaacaaggt caaaagtgac
    26161 aactgcaaat gttgagatag agctgtcaac caatcactaa aacgatcctg aaaagttgca
    26221 attaaattag tcatgaacac tacctccaaa caagtctgct acaaagtctg ttgcaggcgc
    26281 ttttaaaatt gtctcgggat tcgctacctg gcgaatttct ccatcctgca agacagcaat
    26341 acggtccgcc aacttcaagg cttcatccgt atcatgggtt acaaaaatcg ttgtcatccc
    26401 aaactcttta tgcaattctt ttgtcagaac ctgcaactgt tttctcgaaa tagcatccaa
    26461 ggccgaaaag ggttcatcca tgaggaaaat cttgggctga ccaatcatag ctcggacaat
    26521 accgacccgt tgctgttctc caccagataa ttcactaggt aagcgatgcc catactcggc
    26581 tactggtaaa ccaaccttag ccaaaagctc ttctgttttc ttcgtaattt cttccttgct
    26641 ccaccccttc atttcaggaa tgagagcaat attttccgca actgttagat ttggaaaaag
    26701 agcaatagcc tgtaaaacat aaccagtaga aagacgaagt tcacgctcat catagtcttt
    26761 gatgcgcttc ccatccatat aaatatttcc atcagttggt tccaaaagac ggttaatcat
    26821 cttgagcatg gtcgtcttac ctgacccaga aggccctact aaaaccataa attccccatc
    26881 ctcaatctgt aagttgacat ctctcaagac atccttttct gtgtagcata gtgctacatt
    26941 tttgtattca atcattcttt gtcctcattt aaaacttccc tcgattggtc aagtcttcta
    27001 ccttaggcat gacttcctta ttatcccaat gctccacaat tttcccgttc tttaaacgga
    27061 agatatcgta ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat
    27121 agtttccttg tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat
    27181 agtttttata agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg
    27241 ccacataatc actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc
    27301 gaaccagctt tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa
    27361 tttgatctag ttggtcattt tcaggtgttc gatagtagtc aatgacatcc caatgctcaa
    27421 caatacgacc attctcatcc gcacgaaaag tatccgtcgt cacccattga gcttctccac
    27481 cattcagata ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa
    27541 tcttaatctg acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt
    27601 ctttcccgtc aggaacacct gtcgaatgtt ggatataggt agcccctaca gactgggctt
    27661 gagcctcagc aactcgtccg tcttgaatgg catggatgta taggttgtga gcatttttca
    27721 cttgttgtga catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt
    27781 cttgaaaacc ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat
    27841 ccaatttctg actgacacga tgccctactt ctttctggga cttgcctaac tccgttaaaa
    27901 ctaaatactt cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct
    27961 ctagcttttt tatcatagtc gtcagcgtat tattcgcaag tccagtcgca agcgcgatat
    28021 ctgtcgcagt tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt
    28081 cacccctata aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca
    28141 acaaacgaat atgatgggct agcaaatgac catctttcat aacacctcca atttatttcg
    28201 atatcgaaat gaataaaaca attgtaacac tcatcgttct aactgtcaac tatttcgatt
    28261 tagaaataat ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg
    28321 agagtttcta aactccttcg tcctccagtc tacaaaagcc ttccatccgt actatcctat
    28381 attttatgag gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc
    28441 ataattgctt ccatctgttc ttttatagta tattgaagtt ggactagggc actgtatctt
    28501 ctaaaacatt gatagaaagc gatttgaatt tcccaatcaa tttgttcgtc tttatagcat
    28561 ttcgaaactg gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttc
    28621 ctcaatcaat ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt
    28681 ttcgtagcac ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcactcca
    28741 cttccattac agaagtttct tcactactat ggtctcggct gacttctcat gattccttgt
    28801 tactactatt tgaacgctca cgagataggt cttataaaaa atgctttgat ccacaatgga
    28861 atcaaagcat tttaaaaagt tcctcataca taagtgcaga agtcgcagtt cctctgtact
    28921 tggcttcttc tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg
    28981 gatttaggag caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat
    29041 ttgtagtagg cagtttttta gtagtctcta ggagagcagc aactaaatct tcactcaaat
    29101 catgtcgagc atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc
    29161 ctaccacctc ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt
    29221 tcttcaccaa ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg
    29281 tttggtgaga atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat
    29341 ttttcagatg agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga
    29401 taccagcttc ttcagccgtt gtcaaaagga aatccttcat ccctgggaga agcaagtgac
    29461 ctggatcata gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat
    29521 cacctgctgg tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg
    29581 tatgagcgcc acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc
    29641 cgagtttttg acctaataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt
    29701 tatcccaagc ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg
    29761 gtacgatggt atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac
    29821 caccatcaaa aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca
    29881 aatgcggagg aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt
    29941 tgaaacgttg gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg
    30001 taccatctgg cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca
    30061 agacgcgcgg tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat
    30121 ctgtcaccac ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg
    30181 cttcatgacc tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg
    30241 tcatttcagt tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg
    30301 ggaaggtgga tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt
    30361 ctcttgcatg tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc
    30421 aaacaaaaaa acaatacacc atcaaagttg tttggatttt tcatgaaatt tacagaaaat
    30481 agttgacttc cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc
    30541 tgtagctgct aaaacatttc tagaaattaa tttgactttt ctaatagagt tgttcatatc
    30601 ttatttcaat ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc
    30661 ttgttacagg tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg
    30721 gctatcaggt gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc
    30781 gtgctagctt taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag
    30841 aaaatcagat tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg
    30901 aaaatccaag taaatacttc actgccaacg ttgctggtat ggaccaagtt ctcaaagtct
    30961 tatctgaagt tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata
    31021 actgtattga caagccggtg actgaagata ccctgctcga ccctgtcaac ccttatgcag
    31081 agacaaaact gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat
    31141 atgttatttt ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc
    31201 gtgtgaaaaa tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaacatg
    31261 atagcttaaa aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt
    31321 acatttatgt cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag
    31381 aagacagttc ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa
    31441 tctttaaaac tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac
    31501 gtgctagtga cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt
    31561 ggacggctag ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag
    31621 aataggataa caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc
    31681 agaaatttta ttgacagatt agaaaaataa tgttacattt atatccgcag gtatctttcg
    31741 ataccaaatc tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact
    31801 tctactccta gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct
    31861 atttgatttc gaccagcaga cctggctcct ctttcaagag tcccgtctcc caagaactat
    31921 cagtattctc ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac
    31981 ccaaaatcag tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat
    32041 ggtgctgagc ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt
    32101 tatttcatcc atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa
    32161 ggaaaggtgg atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac
    32221 agaagttatc gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc
    32281 cttctccatg attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat
    32341 aaccgtttgg aaattatccc aaaccttcac catcatgaat ctagggaaag aaaccagcga
    32401 gagtttgggg atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac
    32461 gacaagcgtc accatgatta ccgtgggtgg cttaccattt ctcggagtta tcgttcccaa
    32521 tcttgttcgc aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt
    32581 tggtgccaat ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga
    32641 gttgtctgtc agtctcttgc taggaatcat cggtagtctc gtctttatcc tacttctctg
    32701 gagaggggga cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca
    32761 ttattcttgc catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct
    32821 ttgcttggaa gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg
    32881 ggatttcgac cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt
    32941 tgggaattga atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt
    33001 ttcttcaact tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc
    33061 tcttctttct cgccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca
    33121 tcctgctgat ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag
    33181 tcctaatgga tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac
    33241 atcttaacac ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt
    33301 tctttcgaaa agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat
    33361 tgggactcga tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct
    33421 caacggccac tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca
    33481 cctacctgat tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg
    33541 gatttattag cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc
    33601 gtatcagtat gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga
    33661 gggctcgtca gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca
    33721 aggcatttcg cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc
    33781 tggaaaatcg actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct
    33841 cagtatcaaa ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac
    33901 catcctaaaa cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt
    33961 tggacgtttt ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga
    34021 aactctgaac tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg
    34081 ggggcaactc cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt
    34141 gctggacgaa ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct
    34201 tcgacgactg gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat
    34261 ggccagtcag tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg
    34321 aagaaccgat caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac
    34381 gctagctgat atcaataaca aaaagatctg tatctatagc tagtaacata aaagctcaag
    34441 ttagagaacc ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca
    34501 ttttaaaaag gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc
    34561 agcttcttgc tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc
    34621 agtagctctg ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc
    34681 aaagttcctg aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta
    34741 ggatttgaaa aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac
    34801 ctagtgggaa ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc
    34861 gcccttgagc ctgatttgat tatcgcttca ccacgtacac aaaaatttgt agacaaattc
    34921 aaagaaatcg ccccaaccgt tctcttccaa gcaagcaagg atgactactg gacttctacc
    34981 aaggctaata tcgaatcctt agcaagtgcc ttcggcgaaa ctagtacaca aaaagccaag
    35041 gaagaattgg ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct
    35101 gacaaaaaag cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa
    35161 tctcgtttct ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa
    35221 gactcacgcc acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgacatc
    35281 ctctttgtca tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc
    35341 ctagaaaatg cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta
    35401 acaccagacc tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa
    35461 gacatacaaa aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc
    35521 aaagagcaaa ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat
    35581 gaaagctgat gcggtttgaa gagattttcg aagagtataa aattttgaca ttctaaaacg
    35641 catcctatca agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt
    35701 accccacctc attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc
    35761 ttacctgttt tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc
    35821 ttaaaaccat gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga
    35881 caagagggtg gaaagactgg tgagataaaa cgttggtaaa agcgcacaag cgctattaaa
    35941 attcgtttca ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat
    36001 taagacgacg ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc
    36061 gagacaactt atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac
    36121 gcccttcatg gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa
    36181 tttcataaac agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc
    36241 gaagattgtc cttattggcc acacctttaa cacgcgcgac ataaaccttg tcaatctcat
    36301 tacgagggtg aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagactcctg
    36361 atgtatccca gtccaaacga cccacagggt aaatgcgctc tttgacattg ggcaagaggt
    36421 cgacaaccgt cttgcgaccc ttgtcatctg ttacactgga aatgacaccg cgtggtttgt
    36481 taagcagata atagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt
    36541 cgcctgactt gatagtggtt gctagttcac gcaccacttg gccgttaact gtcaccaaac
    36601 cttgcttgat cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact
    36661 tattgattct catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc
    36721 tcaagctcat caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa
    36781 taatccgtag tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt
    36841 atcaggtcca aagcttgcaa ctttgccaag gctccactcg agttaacccc acggatggca
    36901 tcaatttcta tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca
    36961 gcccgagaca agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat
    37021 tgaggcttgg tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct
    37081 gggtcctttt catacttctg ggctaatttt cctaaacttt gctggatgcc tgtcggtggc
    37141 agagagagga gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag
    37201 agcgcttcta tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc
    37261 acttgacttt cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg
    37321 aggatcagct cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct
    37381 tggacattct gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag
    37441 gattctttca caataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg
    37501 tgattttgtg caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg
    37561 tcaatggtcg tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct
    37621 ttggaataat actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg
    37681 aacttgcgat attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct
    37741 gtcacttctg ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc
    37801 atgaccatgt actcacccgt cacttccaga cgcatggcct gcagggttga gacataggct
    37861 agatactgtt cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa
    37921 accagatgca agagtaagtc caggggtcct tcaaaatctt ttaatttaat atccattatc
    37981 tatatttttc taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat
    38041 cgaccttgtt ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg
    38101 atggaaaacc tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat
    38161 agggtttccc tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa
    38221 gcaaggccgt gggaatggtg acaatcctcc gttgggaagc cttgctgatt cgcaacacct
    38281 gaaaatccag attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca
    38341 tttctaggat taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag
    38401 agtctaggta tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca
    38461 agcggtaaaa gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg
    38521 ccgaaatctt tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct
    38581 tgagactggt ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact
    38641 tataggactg cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc
    38701 tgtctctcat tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac
    38761 ggccttgagg atggacttgc gcgtaataat cccttggaaa ataccctctg catccacaac
    38821 cggtaagaag gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga
    38881 aacaaccgct acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg
    38941 gctcaagtca tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa
    39001 ctgtttttca tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt
    39061 cgcatgatcc gcattgtgag tatcaatcaa cacagctaga tttttagcag gggtcaaaaa
    39121 agtttcctcc tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc
    39181 ttggacaaac ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta
    39241 tcatcaatct ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata
    39301 gagcctggat ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga
    39361 ccatagaggc agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg
    39421 aaattgatgt caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc
    39481 accagacgtt ctgggtagcc ggcgtagaag tccatgttcc ctttaacaac gcggatgccc
    39541 tcccaaagtg gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact
    39601 ttgcccacat agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc
    39661 attacaatga tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta
    39721 aggcacggtg agattgacta tttttttctt ccagggttaa ttcagctgat gactcacctg
    39781 tctctcctac aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt
    39841 taatataacc tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga
    39901 ctagggttgt gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt
    39961 gcaagagttt ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc
    40021 agacgcctgg taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca
    40081 tcttgcccgt taattgagaa atggtttctg ccttaaggcg ggcattttcc tcaaaggtca
    40141 tacctgtttc tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc
    40201 ctaacttatc aaagatagct cggaattcct tggttttacc ttcgttacga gtcgcaatca
    40261 acaaggtttc tctgactttg cttgtctcaa agaaatcatg aacattgacc ccttctttag
    40321 gcaattctac atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa
    40381 taacttccaa gtttcgtccc atttcttgat taagcatatc taccacaaag gagaacaaac
    40441 ggtaggtaga accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc
    40501 caaatatttt ggagaattca aacagaggaa aatctgtctg atagtcgctc aaactgttaa
    40561 cgccaccaaa aatactataa gacccaacat accagtcctg gtcatcctta tattcataaa
    40621 ttttatttgt cataattcta catgctccac atgaatctct ttttccagcc attcttcacc
    40681 aatttgtgca aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc
    40741 atcgcgacca cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc
    40801 tgccccacta tcgatgagct gaacctttgg ccccatcaca ttttggataa tagggcgaag
    40861 gagtggataa tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag
    40921 ggtttcatag accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg
    40981 agcaaacttg ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt
    41041 ctgacggtat atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc
    41101 ttgactggac ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc
    41161 tagttgagcc ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat
    41221 cattttgaca tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg
    41281 ctcagcagga cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc
    41341 atggggaagc tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa
    41401 aaaaccaatt ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt
    41461 tcattatgat tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct
    41521 ctctcttaat cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca
    41581 taaccaacat agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc
    41641 tttttattgt tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt
    41701 accttagctt cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca
    41761 ttcaaacgtg ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct
    41821 ccaagagctc ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc
    41881 atttttctcc tgtttctttt tgaatccctt tcattatacc acaaactagc caccctgacc
    41941 agtttgttct acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa
    42001 aagaggtctc cttgctaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    42061 ccacaggttg ctcaaagcac cgctttgagg ttgcagataa aactgacacg gtttgaagag
    42121 attttcgaag agtattaatt tacataaata gccagtgttt gatagggttt gagtagaatt
    42181 ttctcagaca cttctgcatc ttcatagttt gatatcaaaa tctgtccatt ttggtagact
    42241 gctggcaagt cgatttccac ttctttagca taaaagttat tgagcactag taacttttga
    42301 tcctcaaact ggcgttcaaa agcgtagact tgtttgctat cttcaaaggc tggtttgtaa
    42361 cttccttctg aaatgattgg catttcctta cgcagtcgaa tcaagtcttg atagaaggtg
    42421 aaaatcggac cctggatttc attttctaca ttgatgtatt tataggattt accagctttc
    42481 aaccatggag tgcctgttga aaatcctgca ttttccgaag catcccactg catgggaatg
    42541 cgtgaattat cacgcgactt agcttgaata atctggaagg cttcttgctg actctttcct
    42601 tcttctaaga gcgtctgata ggcattaagc gattcgacat ccacataatc agccatagaa
    42661 tcatagtctg ggtcaatcat cccgatttct tcacccatat agatataagg tgtcccacgt
    42721 gacaggtgaa tgctagccgc tagcatggtg gctccttcct tgcggaagtt ttgaatatcg
    42781 acaaaacggt tcaaggcacg tggttgatcg tgattgttcc aaaagagggc actccaaccg
    42841 tctttatcac tcatttcctt accccaacta tggtaaagac tcttcaactc ttcaaaatca
    42901 aagggagcca aggtccactt ttgtccatcc ttatagtcca ccttgaggtg atgaaaatta
    42961 aaggtcatgg ataattcctg acgatcaggc gacgaataga ggacacagtt ttccatggtg
    43021 gtagaagaca tttccccaac tgtcataaag ctatcgtcag atccaaaagt ggcttggttc
    43081 atcatacgca aatagttatg aacgatgggt ttgtctgtat aagctggctt cccttcattt
    43141 tcaggacagt ccactgaaac ctcgtcctta ccgatcaaat tgatcacatc aaatcggaaa
    43201 cctttgatac ccttgtcgcg ccagaaatta acaaccttga aaagctcctt acggacattg
    43261 gaattgcgcc agttaaggtc agcctgggtc tcatcaaata ggtgaagata gtatttccca
    43321 gtatccccga aaggcgtcca tgcagaacca ccaaacttag actgccaatc tgttggttgg
    43381 tcttggatga agaaaaagtc ttgataatac ttatcaccag ctagggcttt ctgaaaccat
    43441 tcatgctctg tcgaacaatg attaagtacc atgtccagca taaagtcaat cttgtgctct
    43501 ttaccgacac acaccatttc ctcaaaatca gccatatcac caaaaagagg atccactgcc
    43561 atataatctg aaatatcgta accattatcc cgttgagggc ttggatagaa tggattgagc
    43621 cagaccatat ccacacctag tttggctaaa tagggaattt tttcgataat cccacggaaa
    43681 tccccaatac cgttttcagt ggtgtctttg taagattttg gatagatttg atagactact
    43741 tttcctttat caagtgtcat ctgtttctcc ttttctgata aaagggagga agcagtcttc
    43801 cgtccctatt tgtgctattt caattatact caatgaaaat caaagaacaa actaggaagc
    43861 tagccacagg ttgctcaaaa cactattttg aggttgcaga tagagctgac gtggtttgaa
    43921 gagattttcg aagagtatta gattcgtgta gcgaccatga gagatgctcc agcttggatc
    43981 gttgtcggat aagttccggg aatagtcgct gtataagcat cttggttggt gatgataaca
    44041 ggagtttctg tcaccagacc tgcagcctta atgacatcca tatcaaaacg aatcagttgc
    44101 tgaccaactg taacgtgatc tccttggact acaagacttt caaaaccttt gccatcaaga
    44161 cctactgtat ccataccgat gtggatgagc aattcaactc cctcgtcaga gacaatgccg
    44221 atggcatgct tggtagggaa aagaaccgtc actgtcccat taactggaga ggtcaactca
    44281 ccttggcttg gttcaatgac tagaccttgc cccatgacac ctgatgcaaa aataggatcc
    44341 gtcgcttgac tcaattcttt cacttggcca gttagtgggc tgataatttc taccgaagta
    44401 agttctactg gttcatggtt cacaaattct gcttcttctt gagcaacgaa ttctgcctgc
    44461 aagttcgtat cgccctctgt ttttgtaaag agaccagcct tgcggaagaa gaaagtcaag
    44521 agcattggaa caacaatcgc aactagcata gttcctgcaa atggcagcat gtattgaggt
    44581 tgaatagaga gaatacctgg caaaccaccg ataccaatag aagccgcagt tacattaaaa
    44641 gtaacggata acatgcctgc aagggctgaa ccagtcatcc cagcaacaaa tggataaata
    44701 tattttacgt taaccccaaa aagagctggt tctgtaacac cgagataggc tgaaatggtt
    44761 gcaggaagtg aaacctgagc ctcacgctca tcatggcgat gcatgaaata atagacaaac
    44821 acggctgagc cttgagcaat attagaaaga gcaatcattg gccatagggc agtgccacca
    44881 gcatccgcaa tcaattgtgt atcaatggca ttggtcatat ggtgcagacc tgtgatgaca
    44941 aatggagcgt agagggcacc aaaaattgca ccgaagagcc atttaactgg accagttaaa
    45001 cctgccaaga caactgatga aagtccttgt ccaattgtcc aaccgattgg tcccaaaaca
    45061 gtatgagcca aaatcaaggc tggaatcaat gacaagaaag gtacaaaaat catagaaatg
    45121 acttctggga tatgcttgcg ccagaagatt tcaagataag acagactcaa acctgcaagc
    45181 aaggctggga taacttgggc ttggtaaccg atacgattaa cagtaaaata gccaaaattc
    45241 caaacccagt ttgccgcgat atcagctgct ggcgttgaag caaccgcata ggcattgagc
    45301 aactgaggcg ataccaaaca gattccgaga acaattccca aaatttggct ggttcccatc
    45361 ttacgagaaa cagaccaagt aatccctact ggtaagaact ggaagatagc ttcaccaggc
    45421 aaccagagga agtgattgac acctgcccaa aactgagagg attctgtgat ggtcttgcca
    45481 tccaacatcg accaatggac accttccaag acattacgga aaccgaggat caatcctccg
    45541 actatcaagg ctggaataat cggagtaaaa atctccgcca gagtggtcat aacacgttgg
    45601 accacgtttt gattactctt agctgcagac ttggctgctt ctttggaaac accctcaata
    45661 cctgaaacgg ctgtaaaatc attataaaag atgggcacgt catttccaat gattacctga
    45721 aattgacctg catttgtaaa agttccttta acagctggaa ttgactcgat agctttaaca
    45781 ttagccttct tatcatctcc taaaacaaag cgcatccgtg tcgcacagtg ggtgacggca
    45841 gtcacatttt ctttgcctcc aattgcctga agcagatctt tggcttcttg ttcaaatttt
    45901 cccatttgat tctccttata cttgtcaaag caagtttgat ttgataagta tattgtaaac
    45961 gataccaaac ttgtctgcaa cttgtttggt ataaaaaggg tgtttttttg taaattttct
    46021 agcacttgta tggtaaaata gatacaggtg ttcattaaac tagactaaaa acctatttaa
    46081 gcaggcaaaa tgaagaaata ccaacaatta tttaagcaaa tccaagaaac cattcaaaac
    46141 gagacttacg ctgtcggaga tttccttcct agcgagcacg accttatgga gcaatatcaa
    46201 gtgagtcgtg ataccgtccg aaaggccctg tctctcctcc aagaggaagg attgatcaaa
    46261 aagataagag ggcaaggttc tcaagtcgtc aaagaagaaa ccgtcaattt ccctgtatcc
    46321 aacctaacca gctaccaaga actagttaaa gaacttggac tgcgctctaa aaccaacgtg
    46381 gtcagtctgg acaagattat tattgataaa aaatcctcac tgataaccgg tttcccagag
    46441 tttcggatgg tttggaaggt ggtccgccag cgtgtggtgg atgatctggt atccgttctg
    46501 gatacagact atctggatat ggaactaatt ccaaatctca ctcgccaaat tgctgagcag
    46561 tctatctatt cttatataga aaatggcctc aaactcctta ttgattatgc tcagaaggaa
    46621 atcaccattg accactcaag cgaccgagac aagattctca tggacattgg caaagaccct
    46681 tatgtcgttt cgattaaatc aaaagtctat ctccaagacg gacgccaatt tcagtttacc
    46741 gaaagtcgcc ataagttaga aaaatttaga tttgtagatt ttgcaaaacg caagaaataa
    46801 aagactgaga caccagatct cagccttttt cggctctata atatttgtag tgggtaaccc
    46861 ccctatggat attatggagc ctattttgtg tagaaaaaaa gtcccatatg acctataatg
    46921 aaaagcgaca aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa
    46981 attactagac attaaagacc ctaatatcca gattttagac atcatcaaga aggatacaca
    47041 caaggaaatc atcgccaaac tggactatga agctccatct tgtcctgagt gcggaagtca
    47101 aatgaagaaa tattactttc aaaaaccttc taaaattcct tatcttgaaa caactggtat
    47161 gcctactaga attctcctta gaaagcgtcg tttcaagtgc tatcattgtt ctaaaattat
    47221 ggt
//
LOCUS       DAVLHM010000011        47046 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLHM010000011 DAVLHM010000000
VERSION     DAVLHM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.011"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VXE45_000647"
     CDS             complement(<1..137)
                     /locus_tag="VXE45_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0788729.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            307..378
                     /locus_tag="VXE45_000648"
     tRNA            307..378
                     /locus_tag="VXE45_000648"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:340..342,aa:Glu,seq:ttc)
     gene            384..457
                     /locus_tag="VXE45_000649"
     tRNA            384..457
                     /locus_tag="VXE45_000649"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Asn,seq:gtt)
     gene            complement(498..1040)
                     /locus_tag="VXE45_000650"
     CDS             complement(498..1040)
                     /locus_tag="VXE45_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0788730.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(1300..2553)
                     /locus_tag="VXE45_000651"
     CDS             complement(1300..2553)
                     /locus_tag="VXE45_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV0788731.1"
                     /translation="MKCFVGLDISSTKLDVCIMLSDTSTPVTASLSNDLSGATEIKNH
                     ILDLNHTYHFERIVIGMEATSLYSFHPAMFFHEDRQLKELHVEIMVEQPNKIKKYRDA
                     FEENKNDTIDAFYIADYFRIERFSPSFLKEEKYMALQHLTRTRLQIIEQLTRTKQHFI
                     ENIYYKCNTLAYQFKKEELSTNLWSSTMMTLMTDEMTLDELANMPLQELDDWLQKLGK
                     GHFKDSEKLAQTIQAAIRGSYRLSKLQQDSVNVILGLLAREIRNLEKMIKEIDKAIED
                     MVETIPEYQCLTSIPGVGKVYAAGIIAEIGQIERFKDHPQVAKFAGLNWREKQSGNSN
                     SQHTSLVNRGNRYLRYYLVEAANSVRRYDDEYKDFYKKKYHEVPKHQHKRAILLTARK
                     FVRLVDVLLRNHQLYTPPRRIMEDN"
     gene            2909..4667
                     /locus_tag="VXE45_000652"
                     /pseudo
     CDS             2909..4667
                     /locus_tag="VXE45_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(4697..7240)
                     /locus_tag="VXE45_000653"
     CDS             complement(4697..7240)
                     /locus_tag="VXE45_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0788732.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYTLMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVLFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSTYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVDFDY
                     FSPIPYEKIENTNNLISVTSSSNEDAAIQYQIEVPENSQIYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(7302..8924)
                     /locus_tag="VXE45_000654"
     CDS             complement(7302..8924)
                     /locus_tag="VXE45_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0788733.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            9130..10155
                     /gene="trpS"
                     /locus_tag="VXE45_000655"
     CDS             9130..10155
                     /gene="trpS"
                     /locus_tag="VXE45_000655"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0788734.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            10307..11785
                     /gene="guaB"
                     /locus_tag="VXE45_000656"
     CDS             10307..11785
                     /gene="guaB"
                     /locus_tag="VXE45_000656"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0788735.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VXE45_000657"
     CDS             complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VXE45_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0788736.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VXE45_000658"
     CDS             complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VXE45_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0788737.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            13463..14713
                     /locus_tag="VXE45_000659"
     CDS             13463..14713
                     /locus_tag="VXE45_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0788738.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            14710..15993
                     /locus_tag="VXE45_000660"
     CDS             14710..15993
                     /locus_tag="VXE45_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0788739.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            16035..16856
                     /locus_tag="VXE45_000661"
     CDS             16035..16856
                     /locus_tag="VXE45_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0788740.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            16867..17412
                     /gene="pgsA"
                     /locus_tag="VXE45_000662"
     CDS             16867..17412
                     /gene="pgsA"
                     /locus_tag="VXE45_000662"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0788741.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            17409..18236
                     /locus_tag="VXE45_000663"
     CDS             17409..18236
                     /locus_tag="VXE45_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0788742.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            18221..19060
                     /locus_tag="VXE45_000664"
     CDS             18221..19060
                     /locus_tag="VXE45_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0788743.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            19053..19847
                     /locus_tag="VXE45_000665"
     CDS             19053..19847
                     /locus_tag="VXE45_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0788744.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            19906..20724
                     /gene="mreC"
                     /locus_tag="VXE45_000666"
     CDS             19906..20724
                     /gene="mreC"
                     /locus_tag="VXE45_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0788745.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            20724..21218
                     /gene="mreD"
                     /locus_tag="VXE45_000667"
     CDS             20724..21218
                     /gene="mreD"
                     /locus_tag="VXE45_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0788746.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            21312..22490
                     /locus_tag="VXE45_000668"
     CDS             21312..22490
                     /locus_tag="VXE45_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0788747.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            22714..23493
                     /gene="rpsB"
                     /locus_tag="VXE45_000669"
     CDS             22714..23493
                     /gene="rpsB"
                     /locus_tag="VXE45_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0788748.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            23559..24599
                     /locus_tag="VXE45_000670"
     CDS             23559..24599
                     /locus_tag="VXE45_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0788749.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            24845..25168
                     /gene="tnpB"
                     /locus_tag="VXE45_000671"
     CDS             24845..25168
                     /gene="tnpB"
                     /locus_tag="VXE45_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0788750.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(25309..25596)
                     /locus_tag="VXE45_000672"
                     /pseudo
     CDS             complement(25309..25596)
                     /locus_tag="VXE45_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25587..25985
                     /locus_tag="VXE45_000673"
     CDS             25587..25985
                     /locus_tag="VXE45_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788751.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VXE45_000674"
     CDS             complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VXE45_000674"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0788752.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(27387..28022)
                     /locus_tag="VXE45_000675"
     CDS             complement(27387..28022)
                     /locus_tag="VXE45_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0788753.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            28078..29376
                     /locus_tag="VXE45_000676"
     CDS             28078..29376
                     /locus_tag="VXE45_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0788754.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            29373..30035
                     /locus_tag="VXE45_000677"
     CDS             29373..30035
                     /locus_tag="VXE45_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0788755.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            30115..30663
                     /gene="raiA"
                     /locus_tag="VXE45_000678"
     CDS             30115..30663
                     /gene="raiA"
                     /locus_tag="VXE45_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0788756.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            30799..32772
                     /locus_tag="VXE45_000679"
     CDS             30799..32772
                     /locus_tag="VXE45_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0788757.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            32769..33221
                     /gene="rplI"
                     /locus_tag="VXE45_000680"
     CDS             32769..33221
                     /gene="rplI"
                     /locus_tag="VXE45_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0788758.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            33265..34617
                     /gene="dnaB"
                     /locus_tag="VXE45_000681"
     CDS             33265..34617
                     /gene="dnaB"
                     /locus_tag="VXE45_000681"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0788759.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            34619..34885
                     /locus_tag="VXE45_000682"
     CDS             34619..34885
                     /locus_tag="VXE45_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788760.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            34974..36320
                     /gene="cbpD"
                     /locus_tag="VXE45_000683"
     CDS             34974..36320
                     /gene="cbpD"
                     /locus_tag="VXE45_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0788761.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      36403..36505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            36576..36866
                     /locus_tag="VXE45_000684"
     CDS             36576..36866
                     /locus_tag="VXE45_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0788762.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFSNVKINVGEILSIDEKLEKYTETTH"
     gene            36829..37587
                     /locus_tag="VXE45_000685"
     CDS             36829..37587
                     /locus_tag="VXE45_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788763.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWFNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            37625..38632
                     /locus_tag="VXE45_000686"
     CDS             37625..38632
                     /locus_tag="VXE45_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0788764.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            38632..39360
                     /locus_tag="VXE45_000687"
     CDS             38632..39360
                     /locus_tag="VXE45_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788765.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPQGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            39479..39937
                     /locus_tag="VXE45_000688"
     CDS             39479..39937
                     /locus_tag="VXE45_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0788766.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            39939..42371
                     /locus_tag="VXE45_000689"
     CDS             39939..42371
                     /locus_tag="VXE45_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0788767.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            42692..43345
                     /gene="rr06"
                     /locus_tag="VXE45_000690"
     CDS             42692..43345
                     /gene="rr06"
                     /locus_tag="VXE45_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0788768.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            43342..44673
                     /gene="hk06"
                     /locus_tag="VXE45_000691"
     CDS             43342..44673
                     /gene="hk06"
                     /locus_tag="VXE45_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0788769.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            44768..45295
                     /locus_tag="VXE45_000692"
     CDS             44768..45295
                     /locus_tag="VXE45_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0788770.1"
                     /translation="MVLAIILVIFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            45374..>47046
                     /gene="pspC"
                     /locus_tag="VXE45_000693"
     CDS             45374..>47046
                     /gene="pspC"
                     /locus_tag="VXE45_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0788771.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLVMGSVVHATEKEVTT
                     QVPTYSNMAKTEHRKAAKQVVDEYIEKMLREIQLDRRKHTQNFAFNMKLSAIKTEYLY
                     GLKEKSEAELPSSEAELPSEVKAKLDAAFEQFKKDTLKLGEKVAEAEKKVAEAEKKAK
                     AQKEEDRRNYPTITYKTLDLEIAESDVEVKKAELELLKEEAKTRNKDTIKQAKAKVES
                     KQAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKDKLKRRTKRAVPGEPATPDKKENGA
                     KSSDSSVGEETLPSPSLKPEKKVAEAEKKVAEAEKKAKDQKEEDRRNYPTNTYKTLEL
                     EIAESDVKVKEAELELVKEEAKESRNEEKVKQAKAKVESKQAEATRLEKIKTDRKKAE
                     EEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEED
                     YARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNG
                     SWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGS"
BASE COUNT        14838 a         7753 c        10094 g        14361 t
ORIGIN      
        1 tttcctttct gttgataggc tagtaacaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatat tttagagaaa
      241 aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata tctgctacag
      301 atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt
      361 cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg catgactgtt
      421 aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg gaacacagct
      481 gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa gtctgttatt
      541 tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc aaaaagtgca
      601 tgagttagat agatgctact atattctaat tcagtggtat ttagattcag ttgcataaat
      661 cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa attttggatt
      721 tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc tagatattca
      781 aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat atattcaaat
      841 gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt atagtgagta
      901 tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga aattttatca
      961 aatggctgtt ccatcagtaa ttgtaccata gcgttttcaa tagttcgctt tgtttttaag
     1021 cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata tgtctaaaaa
     1081 tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat caaaatttta
     1141 gacaatatgt ttaaaaaagt ctagtggtaa aatgtcaagc gaccccccgc tcaaagtttg
     1201 aaaactattt caaaaaaagg gtgcactaaa gaagccctac tgaaaacgat gttttcacac
     1261 tgtttttagt agattttcaa ggagaggtgc agatataact tagttatctt ccataatcct
     1321 ccttggtggc gtatagagtt gatggttgcg tagtagcaca tccaccagac gcacaaattt
     1381 tctagcggtt agtaagatgg ctcgtttgtg ttggtgttta ggtacttcat ggtatttctt
     1441 cttatagaaa tccttgtatt cgtcatcata acgccttacc gagttggcgg cttcaaccag
     1501 gtagtagcgc agataacgat tgcccctatt cacaagcgaa gtatgttgtg agtttgagtt
     1561 accagattgc ttttctctcc aattcagacc agcaaatttt gcgacctggg gatggtcttt
     1621 aaagcgttcg atttgtccaa tttcggcaat gataccagca gcgtagacct tcccgacccc
     1681 aggtatggag gtcaggcatt gatattcagg aatggtttcc accatatctt caatggcctt
     1741 atcaatttcc ttgatcattt tttccaggtt tcgaatttcc cgagccagaa gtccgagaat
     1801 gacattgact gaatcttgtt ggagtttaga gaggcgataa gaacctctga tagcggcttg
     1861 aatggtttga gcaagcttct cagagtcctt aaaatgccct ttacccagtt tttggagcca
     1921 atcatctaat tcttgaagag gcatgttagc aagttcgtct aaggtcatct catctgtcat
     1981 caaggtcatc atcgttgaac tccataggtt agtagagagt tcttctttct tgaattgata
     2041 agccaaggta ttgcacttgt agtagatatt ttcaatgaag tgctgtttgg ttctggttaa
     2101 ttgctcgatg atttggagtc tggttcttgt gagatgttgg agagccatgt atttctcttc
     2161 ttttaaaaaa gaaggtgaaa atcgctcaat acggaaataa tccgcaatgt agaaagcatc
     2221 aatggtatcg tttttgtttt cttcgaaagc atcccgatac ttcttgattt tattaggttg
     2281 ttcgaccata atctcaacat gtagttcttt caactgccta tcttcatgga agaacatagc
     2341 agggtggaaa ctgtagagac tggttgcttc catgccaatg acaatccttt cgaagtgata
     2401 ggtatgattc aaatcaagga tatgattctt aatctctgtt gccccagaaa ggtcattaga
     2461 gagggaagca gtgacggggg tgctagtatc actcaacatg atacacacat ctaattttgt
     2521 agagctgatg tctaaaccga caaaacattt cattaaggaa ggtctccttt ccattagatt
     2581 tggaagtttt tttgactact gtaaggtttc ccagaaacac cttgttccaa catcctcgca
     2641 taagagaatc cttatcacag cctgacagag ccgcctgcat cctactagat acagaagtca
     2701 agctgtggaa acagctagtg tgttggaagt ttgaacaagg cttgggtaac agacttttta
     2761 atgaagtcca agcaacaagg agaaaaagaa acaaccatga gtccattcca tgactctatt
     2821 gttctagaaa accttgcaat agtcaagtga taacgaataa aacttgggat tgaaatatcc
     2881 ccatgattat atattacgag gagaaactat gtttaaagaa tggaaagcaa tttaaaaaaa
     2941 acaaccttta ttattgtcat gatcgggatt tctcttattc cagctctgta caatatcata
     3001 tttttgtcat caatgtggga tccatatggg caattgtctg acttacctgt ggcagttgta
     3061 aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa agacatggtg
     3121 tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga ggaaggaaag
     3181 aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga tttatctgaa
     3241 aaagcaacta cattatccaa tattcaatcg acagcagctt atcaatcatt gacaagtgag
     3301 caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat tcaatcggct
     3361 cagtcaattg tagctttagt acaagattta cagggaagtt tagaaaactt acaaaatcaa
     3421 tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat tacttctact
     3481 tctttgatag gattgtcaag tggattaaca gagatacaag gagctgttac tagcaaatta
     3541 gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg tgttgataaa
     3601 gtttctcagg gcgcaagtca actaagtgaa aaaaatgcta ccttgacagg tagtttggat
     3661 caattagttt caggctcaaa caccttgaca caaaaatctt ctagcttgac agcaggagtt
     3721 ggtcaattag ttgaaaaaac tccagaatta gtatctggta ttgaaaaatt atcaactggc
     3781 tccaattaat tgaatcaaaa gagtcaagaa ttgatagcag gagttgataa attgcagtca
     3841 ggctctagcc aactagctga caaatccagt cagttacttt caggtgtttc tcaattagaa
     3901 agtggagcta ataaattggc agatggagct gggaaactag cagaaggtgg aacaaagtta
     3961 acttctggat tggaaggttt acagacagga cttgcttctt taggacaagg actaggtaat
     4021 gctagtgatc aactcaaatc agcatcaaca gaatctaaaa atgcagagat tttgtcaaat
     4081 ccactcaatc tttccaaaac agacaatgac caagttcctg taaatggaat tgcaatggct
     4141 ccttatatga tatcagttgc tctttttgtt gcagcaatat caacgaatat gatctttgcg
     4201 aagttacctt caggacgtca tccagagagc cgttgggctt ggttgaaatc tcgagctgaa
     4261 ataaatggta ttatagctgt tttggcaggg attttggtat atggaggagt tcatcttatt
     4321 ggtctaactg ctaatcatga aatgagaaca tttattctca tcatcttaac aagtttagta
     4381 ttcatgtcta tggtgaccgc tttaacaaca tggaatagcc gtataggagc tttcttctcg
     4441 cttatttttc ttttattaca gttagcatca agtgcaggta cctatccgct tgctttgaca
     4501 aatgatttct ttagagctat taatccttgg ttgccaatga gttattcagt ttcgggatta
     4561 cgacaaacaa tctccatcaa caagtcattt tcctagctgt catactagct ctatttactg
     4621 gtttaggtat gctagcctat caacctaaga aaatggaaga agattaaaaa aatcgaccga
     4681 ttaactggtc gattttttat gccttagatg actttcgtct gtgattatag attccaaata
     4741 gtaagagaga agtaaaggaa cagattgctc cagtaataaa accattggga atgaaggaaa
     4801 gtgtaatagt tcctttcccc ttgggaatgt caactttcat aaatccagtt tgagcttgtt
     4861 taatttctat tttcttacca tcttggtagg cagaccaacc tttgtcataa ggaatggtga
     4921 agaaaataga tgtatcttgt tggacatcat atgtagcaaa aaccttgttt ttagaagttg
     4981 atactgtgac aggttgttct ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta
     5041 aacgatagaa ggtaggagat tcaaatgata cttgtgaatt tccagggaaa ctaacattga
     5101 tattgaaagt ttttttctct ttagtatatc ctagattaaa gaaggagaag acattatcag
     5161 ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac cttcttttgt ttatcgttag
     5221 aaaagtgaag gtttatgaaa gagagataaa tttggctgtt ttctggaact tcaatttgat
     5281 actggattgc tgcatcctca tttgaagaac ttgtgacact aatcaaatta ttagtatttt
     5341 ctattttttc ataagggatt ggagaaaaat aatcaaaatc aacgttagca agttgattta
     5401 aaaacgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt
     5461 gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt
     5521 gatagatatc tttaaaacca tacttatcaa taggactgtc tgagatattg tactggatac
     5581 caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag
     5641 aggatttaaa cccaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa
     5701 attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt
     5761 tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata gctgggatat
     5821 ctcgactata agtacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag
     5881 atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat
     5941 tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt
     6001 caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg
     6061 tagctaaaaa tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt
     6121 ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag
     6181 catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt
     6241 ctatgtaaaa gcttgcaatt agaaatgcaa agaataatac atatatgagt ttcacgtgaa
     6301 acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaaaggaagt agtccaacaa
     6361 aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa
     6421 agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc
     6481 catgtgtctg taaatcaaac agagtgggaa gagtcataat caaactagcc ataccagcta
     6541 aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa
     6601 tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt
     6661 gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta
     6721 gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag gtttttatct
     6781 ctaattgact gacagtgaaa ctcatcagag tataggaagt agataaggct agttttaaag
     6841 tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc
     6901 caaattttaa gagagtggtc agataaacag catctggcat attcgttaga tcaaaaaagt
     6961 aaaccagagg tgagagaaaa ctacccaagt aataactaga cagagcatag aagtttagcc
     7021 ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg
     7081 ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat
     7141 tccagtagat accttgagat agatatactc cagacataat cactacagga atgatgagag
     7201 aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag
     7261 aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct
     7321 ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg
     7381 tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg aataaattcg
     7441 tggtcatggc tagcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt
     7501 gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt
     7561 aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca
     7621 ggtttgttaa cttcatctcc agagaagagc atacggccga ggaagccacg taggaaagta
     7681 ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct
     7741 gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg
     7801 acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata
     7861 tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc
     7921 aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca
     7981 atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct
     8041 tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca
     8101 ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca
     8161 ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt
     8221 ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt
     8281 aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct
     8341 tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca
     8401 tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat
     8461 tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag
     8521 gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca
     8581 cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg
     8641 atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag
     8701 tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca
     8761 gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta
     8821 gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt
     8881 ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat
     8941 gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt
     9001 tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat
     9061 tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag
     9121 gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat
     9181 attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat
     9241 gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa
     9301 accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca
     9361 aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat
     9421 tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt
     9481 tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa
     9541 gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca
     9601 atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc
     9661 ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta
     9721 gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg
     9781 gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag
     9841 gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca
     9901 gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat
     9961 gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag
    10021 cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca aaaaggtagt
    10081 gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt
    10141 cattacttta actaagttta ttttacaaga aactatcatt tctatctcga agaaaagata
    10201 gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa
    10261 tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga
    10321 cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag
    10381 tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa
    10441 tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat
    10501 tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga
    10561 cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac
    10621 gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt
    10681 tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct
    10741 tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt
    10801 tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat
    10861 tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga
    10921 tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gaatttggtc gtcttctagt
    10981 tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc
    11041 aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa
    11101 aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac
    11161 tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg
    11221 accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc
    11281 tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg
    11341 gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct
    11401 tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg
    11461 taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga
    11521 ccgttatttc caaggttctg tcaatgaagc aaacaagctc gttccagaag gaattgaagg
    11581 tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg
    11641 ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt
    11701 tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa
    11761 tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt
    11821 tcttttacaa tgttgtcaat ttccatttac agaagcttta ccatcctgaa tagtgaagat
    11881 acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg
    11941 gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat
    12001 cacatcgtca agcagtaata taggagattc tgtggtaatg ctttccatta attcgatttc
    12061 tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc
    12121 catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt
    12181 aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg
    12241 tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga tctgattaga
    12301 gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg
    12361 attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc
    12421 atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt
    12481 ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg
    12541 tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt
    12601 catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg
    12661 gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc
    12721 tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg
    12781 actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt
    12841 acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg
    12901 aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct
    12961 tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc
    13021 tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt
    13081 tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta
    13141 tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa gtaaacagaa
    13201 tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt
    13261 agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt
    13321 tggtattata ccatattttc ctaaaaatag tgagagagac agcgagaaat gtaagcgatt
    13381 tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag
    13441 tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca
    13501 atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga
    13561 tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc
    13621 cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa
    13681 ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga
    13741 gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct
    13801 tttttcaccc gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa
    13861 acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga
    13921 attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa
    13981 tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa
    14041 tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt
    14101 agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta
    14161 ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt
    14221 aggttatcat taccgttcta aatatggtga tgagcaacat ttacccatga ttgtaatgaa
    14281 tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg
    14341 attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc
    14401 tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga
    14461 tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg
    14521 gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc
    14581 cttatttgga aaatcttcag cagactttaa aagttggatt gcaaagcttg aacaaattga
    14641 caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt actttatgga
    14701 aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt aaaagaaaag
    14761 gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt
    14821 aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa
    14881 gttgacggat atgtaaaaca atatcctgga ggaattgctc attttcttga acataaatta
    14941 tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt
    15001 aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta
    15061 gaaaatttag atttacttga tgaattggta acatcagcac actttactga agcttccatt
    15121 ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg
    15181 tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata
    15241 gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca
    15301 aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga
    15361 gtacaggact attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga
    15421 gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct
    15481 cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga
    15541 catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt
    15601 caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt tgaaataaca
    15661 agtcgctttc attttgtcat gttgacaata gatacgaaag agccagttgc tttgtctcat
    15721 caatttagga aggctattcg taattttaca aaggatttag atattacaga ggaacattta
    15781 gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt
    15841 attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt
    15901 ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt
    15961 gacatagttg attttacaat attcccatcg tagtaaccta tcataataga cactagaaag
    16021 aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca
    16081 atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg
    16141 aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct
    16201 tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt
    16261 ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta
    16321 gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc
    16381 tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc
    16441 aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct
    16501 ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag
    16561 gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat
    16621 tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg
    16681 taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa
    16741 caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt
    16801 tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa
    16861 aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata
    16921 cctattttta tctttatttt gacgatagga aattcgatag agagtcatat agttgcagct
    16981 attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg
    17041 aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg
    17101 tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt
    17161 atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca
    17221 attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgctattatt
    17281 ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc
    17341 actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt
    17401 ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc
    17461 agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga
    17521 ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg
    17581 aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga
    17641 atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga
    17701 ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga
    17761 aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc
    17821 cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa
    17881 gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag
    17941 aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta
    18001 cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa
    18061 ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat
    18121 tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac
    18181 ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa
    18241 tgtgaatttt atatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc
    18301 tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc
    18361 aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt
    18421 tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt
    18481 tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt
    18541 tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga
    18601 gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc
    18661 agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc catctatatt
    18721 agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct
    18781 gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga
    18841 tgttgctgaa tatgctaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg
    18901 caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc
    18961 taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc
    19021 gattaagata gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata
    19081 tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc
    19141 tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag
    19201 cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga
    19261 agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg
    19321 ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg
    19381 ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa
    19441 ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga
    19501 aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct
    19561 tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag
    19621 aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga
    19681 caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg
    19741 gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg ctgaccattc
    19801 ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa
    19861 ttgataaaaa gttactgtaa cagtttttga tataaaggta gggatatgaa ccgttttaaa
    19921 aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg
    19981 acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga
    20041 gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca
    20101 cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca
    20161 aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag
    20221 tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct
    20281 tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta
    20341 gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata
    20401 gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc
    20461 tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt
    20521 agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta
    20581 ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca
    20641 gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg
    20701 atagaattag tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc
    20761 ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc
    20821 atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat
    20881 cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt
    20941 tccatctaat agggattaca actctcttat ttatcttatt gggagccttc cttcataaat
    21001 tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat
    21061 tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca
    21121 tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta
    21181 ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa
    21241 aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt
    21301 atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt
    21361 ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc
    21421 aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc
    21481 aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg
    21541 atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca
    21601 ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg
    21661 taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg
    21721 ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag
    21781 ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg
    21841 ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa
    21901 aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc
    21961 tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag
    22021 cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact
    22081 taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc
    22141 gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa
    22201 aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg
    22261 cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga
    22321 atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc
    22381 aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca
    22441 atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg
    22501 gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc
    22561 aaaatagctt gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa
    22621 tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca
    22681 agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt
    22741 cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag
    22801 tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac
    22861 gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc
    22921 gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa
    22981 tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa
    23041 cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt
    23101 cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggt
    23161 ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag
    23221 caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc
    23281 aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct
    23341 gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat
    23401 gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa
    23461 atcgttgaag ttgtagaagg tgacaacaaa tagtaattac ctaggagggc ggggcttagc
    23521 ccggctctcc tattttcaaa aaatatagga gaattaaaat ggcagaaatt acagctaaac
    23581 ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa aaagcgcttg
    23641 tagaaacaga cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa ggtatggcta
    23701 aggcagctaa gaaagctgac cgtgttgctg cagaaggttt gactggtgtt tatgttaacg
    23761 gtaatgttgc agcagttatt gaagtaaacg ctgaaactga cttcgttgca aaaaacgctc
    23821 aattcgttga attggtaaat actacagcta aagtcattgc tgaaggaaaa cctgctaata
    23881 atgaagaagc tcttgctttg ataatgcctt caggtgaaac tcttgaagct gcatacgtat
    23941 ctgcaacagc aactatcgga gagaaaatct cattccgtcg ctttgcattg attgaaaaaa
    24001 cagacgcaca acactttgga gcataccaac ataacggtgg acgtatcggt gttatttcag
    24061 ttgttgaagg tggagacgaa gcacttgcta aacaattgtc aatgcacatc gcagcgatga
    24121 aaccaacagt tctttcttac aaagaattgg atgagcaatt cgttaaagat gagttggcac
    24181 aattgaatca cgttatcgac caagacaacg aaagccgtgc aatggttaat aaaccagctc
    24241 ttccacactt gaagtatgga tcaaaagctc aattaactga tgatgttatt gctcaagctg
    24301 aagctgacat caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc tgggacaaaa
    24361 ttatcccagg taaaatggat cgcttcatgc ttgataatac taaagttgac caagcttaca
    24421 cacttcttgc acaagtttac atcatggatg acagcaagac agttgaagca taccttgaat
    24481 cagttaacgc ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt atcgagaaag
    24541 ctgcaaacga cttcgaagct gaagttgcag ctacaatggc agcagccttg aataactaat
    24601 aatagaaagg aagcaaattg cttccttttt tgtatagggc ttagattttt cctgaaattg
    24661 ttttttcccc agtctcactc gattagaata attaaaacaa aaagccctat aataagggct
    24721 aagtgcattt aggagactat acttcaaatt catagtaagc gcgtcataac aaggtatcta
    24781 tcctaattcc ccaacttcca gtataccaga taaaaaataa ttatcggagg aaaggtattg
    24841 tactatgata attcaactaa gtgatttagg tcaagttcac cttgtttgtg gcaagacaga
    24901 tatgaggcag ggaatagact cattagccta tgtagttaaa acccactttg aattggatcc
    24961 tttctccgat caagtctttc tcttttgtgg tggacgtaaa gaccgcttta aagttcttta
    25021 ctgggatggt caaggatttt ggatattata taaacgcttt gagaacggaa aactgacttg
    25081 gtccagtaca gaaaaggatg tcaaagctct cacatctgaa caagtagatt ggctgatgaa
    25141 gggcttttct atcactcccc aaatatagtg gatttaaact agaatagtac acctctgctt
    25201 ctaaaacatt gttagaaatc gatttgacta tcctgttctt atttcatttt actataaatt
    25261 catcagaaag tcgtgatttc tattgaaatg aggactttct ttttatactc atctgttttc
    25321 aaaaagcatt ctagtccgtc tccgattaac gatggacttt atcacctcct tctccagtcc
    25381 ttgtatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
    25441 tttccacact tgttcaatgg ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc
    25501 aatattagtc ggaatcttta aggtacttga tttatgccat atagcattgt ccataacgag
    25561 taaaagataa tcatctggat aagcttgtga aagctcctat tcctaaagcc cctttagcgc
    25621 ataactttgg ctcagcttct attatcgctc acaccatcca tcagaagttt aatctgaagg
    25681 tacccaatta tcgccaagaa gaagattggg ctaggatggg tttaccaatc acacgtaagg
    25741 aaatctctaa ttggcatatc aagacgagtc aatactattt ggagcccctt tataacctct
    25801 tgcgagagag actattgact cagcccttac ttcatgcgga tgaaacttct tatagggtgc
    25861 tagagagtga tagtcagctg acttactatt ggactttttt gtctgggaaa gctgagaaac
    25921 aagggattac gctttaccat catgttctaa tcgatttgtt catatcttat ttcaatccat
    25981 tataaatagt gagaaatatc tatcctatct tctagaatgt cttccaaacg tggaaactct
    26041 cgtaaacaaa gaggttttag aggcctattt accatggact aaagttgtac aagaaaagtg
    26101 caaataagaa atctccagat taggaactat ccgtgagttc tctagtctgg agatttttca
    26161 atagacttcg ttattggacg gttacaattc ataaagtgct gtagagagat aacgttcacc
    26221 gttatctggt gctagggcaa ggactttttt acctgtacct aattttttgg caacctcgat
    26281 ggctccgtag atagctgcag ctgaggaaat ccctacaagg aagccttctt ttccaccaat
    26341 ttcacgtccg agtgcaagag cgtcatctga tgttacacga acgataccat cataggcttt
    26401 agtatcaagt gtatcaggaa taaatccagc tgagatacct tgaattttgt gaggaccagg
    26461 tttttcacca gatagaatag cagattcatc tgcttctact gcaaaaactt gaatgttaga
    26521 attttctgat ttgagtgcat gagaaacacc agaaatcgtt ccaccagtac ctactccagc
    26581 aacaaaggca tctaatccat ctttaccgaa agcagctagt atctcagctc ctgttgttct
    26641 ttcgtgtact tctggattag ctggattgtc aaattgaaga ggaaggaaac catcacgttc
    26701 agcagcgatt tcttgagcct tagcaatagc acctttcatt ccctcgctac caggagttag
    26761 gacgagttca gcaccataag cttggataat tttacgtcgt tctacactca tagtttcagg
    26821 cataacgatg acgactttat accctttagc agcacctacc catgaaagtc caataccggt
    26881 gtttccactt gttgcttcaa caatagtaga accaggtttc agaataccat cttgttcagc
    26941 tttttcaatc atgctaaggg caatacggtc ttttacagat gaaccaggat taaatgcttc
    27001 aagctttata tagacgtctg cagcaccttc tggcacgatg ttgttaagtt taacaatcgg
    27061 tgtttgaccg attaattcag taatgttgtt ataaatagac atatgaatac ctctttgtat
    27121 aagatatctt tagtataacg ctatccatac catttgtaaa atatagaaat cctatcgaag
    27181 cgataggatt tctatatatc atagatcaaa gtcattaatt ttcaagtgat tgcgttcagc
    27241 taattctagt aaataggtgt gaaggaaaac gatatcaggt ttcgtttgaa ttgcttcatt
    27301 ttctagtata ttttggtacg catcttttta ttttgctcgc taaagtagtt gtgagaatgt
    27361 caacgaaacg ctgtattatt cattgtttac actaagttta caggaacttc aacctctcgt
    27421 aaaccttggt cagttaaagt gacttttcca ttaaaaaact ccacaagtgc agctttaata
    27481 gtttcttttt cttctttatc aacataaatc atcgtatcga cttgatctgt aaagtttgta
    27541 tccagctcca tgagaccatg ttctttaagg aagttactgt actcttggta ctgagcataa
    27601 gacatttgaa tagcaatgcc agcctgttct tttatttcaa taataccaat ttctttgaca
    27661 gctaaggcga cactgccggc gtaagcacga attagtcctc cagcgcctag tttaatacca
    27721 ccaaagtagc gtgtcacgac cacacagaca ttggtgagat tgtgattttc tagtacccca
    27781 agcatgggaa caccagcagt accactaggc tcaccatcat cacttgtacg tttaatttca
    27841 ctacgttctc caataatgaa ggcagagcag ttatgtgtcg ctttgtagtg ttcttttttg
    27901 atggcagtaa tgaagtcacg agcctcttct tcgctataaa cacgcttggc atggcagata
    27961 aagcgagatt ttttgatttc ttcttggact tgaccgtcct ctttaattgt cctaaattcc
    28021 atgatttaat tgtactaaaa aatcatctaa agtgctagtt tttacgaata aagaagtatg
    28081 aaagtaaatt tagattatct cggtcgttta tttactgaga atgaattaac agaagaagaa
    28141 cgtcagttgg cggagaaact tccagcaatg agaaaggaga aggggaaact tttctgtcaa
    28201 cgctgtaata gtactattct agaagaatgg tatttgccca tcggtgctta ctattgtcga
    28261 gagtgcttgc tgatgaagcg agtcagaagt gatcaaactt tatactattt tccgcaggag
    28321 gattttccaa agcaagatgt tctcaaatgg cgcggccaat taactccttt tcaagagaag
    28381 gtgtcagagg gattgcttca agtagtagac aagcaaaagc caaccttagt tcatgcggta
    28441 acaggagctg gaaagacaga aatgatttat caagtagtgg ctaaagtgat caatgcgggt
    28501 ggtgcagtgt gtttggctag tcctcgcata gatgtttgtt tggagctgta caagcgcctg
    28561 caacaggatt tttcttgcgg gatagctttg ctacatggag aatcggaacc ttattttcga
    28621 acaccactag ttgttgcaac aacccatcag ttattgaagt tttatcaagc ttttgatttg
    28681 ctgatagtgg atgaagtaga tgcttttcct tatgttgata atcccatgct ttaccacgct
    28741 gtcaagaata gtgtaaagga gaatggattg agaatctttt taacagcgac ttcgaccaat
    28801 gagttagata aaaaggtccg tttaggagaa ctaaaaagac tgaatttacc gagacggttt
    28861 catggaaatc cgttgattat tccaaaacca atttggttat cggattttaa tcgctactta
    28921 gacaagaatc gtttgtcacc aaagttaaag tcctatattg agaagcagag aaagacagct
    28981 tatccgttac tcatttttgc ttcagaaatt aagaaagggg agcagttagc agaaatctta
    29041 caggagcaat ttccaaatga gaaaattggc tttgtatctt ctgtaacaga ggatcgatta
    29101 gagcaagtac aagcttttcg agatggagaa ctgacaatac ttatcagtac gacaatcttg
    29161 gagcgcggag ttaccttccc ttgtgtggat gttttcgtag tagaggccaa tcatcgtttg
    29221 tttaccaagt ctagtttgat tcagattggt ggacgagttg gacgaagcat ggatagaccg
    29281 acaggagatt tgcttttctt ccatgatggg ttaaatgctt caatcaagaa ggcgattaag
    29341 gaaattcaga tgatgaataa ggaggctggt ctatgaagtg cttgttatgt gggcagacta
    29401 tgaagactgt tttaactttt agtagtctct tacttctgag gaatgatgac tcttgtcttt
    29461 gttcagactg tgattctact tttgaaagaa ttggggaaga gaactgtcca aattgtatga
    29521 aaacagagtt gtcaacaaag tgtcaagatt gtcaactttg gtgtaaagaa ggagttgaag
    29581 tcagtcatag agcgattttt acttacaatc aagctatgaa ggattttttc agtcgctata
    29641 agtttgatgg agacttcctg ttaagaaaag ttttcgcttc atttttaagt gaggagttga
    29701 aaaagtacaa agagtatcaa tttgttgtaa ttcccctaag tcctgataga tatgctaata
    29761 gaggatttaa tcaggttgag ggcttggtag aggcagcagg ctttgagtat ctggatttat
    29821 tagagaaaag agaagagaga gccagttctt ctaaaaatcg ttcagagcgc ttggggacag
    29881 aacttccttt ctttattaaa agtggagtca ctattcctaa aaaaatccta cttatagatg
    29941 atatctatac tacaggagca actataaatc gtgttaagaa actgttggaa gaagctggtg
    30001 ctaaggatgt aaaaacattt tcccttgtaa gatgaggaaa aaatttgcaa aaatagaatg
    30061 aaagcgttat aataaaatca taaaaacaaa aatgtttaga aagaaggtac tcatatgatt
    30121 aaatatagta tccgtggtga aaacctagaa gtaacagaag caattcgtga ttatgtagtt
    30181 tctaaactcg aaaagatcga aaagtacttc caaccagaac aagagttgga tgcccgaatt
    30241 aacttaaaag tttatcgtga aaaaacggct aaagtggaag taacgattcc gcttggatct
    30301 attactctcc gcgcagaaga tgtatctcaa gatatgtatg gttcaattga ccttgtaact
    30361 gataaaattg aacgtcagat tcgtaaaaat aaaacaaaaa tcgagcgtaa aaataaaaat
    30421 aaggtagcaa ctggtcaatt atttacagat gctttggtgg aagattcaaa tgttgtccag
    30481 tctaaagttg ttcgttcaaa acaaattgat ttaaaaccaa tggatttgga agaagcaatt
    30541 ctacaaatgg atttattggg gcatgatttc tttatctatg tggatgttga agatcagaca
    30601 accaatgtga tttatcgtcg tgaggatggc gaaattggtt tgttagaggt taaagaatct
    30661 taatttcaat atgtgtaaag gtaggtttac tgaattgtaa actacctttt tcttataatt
    30721 gatagaatta ctgattacac ttttaaaaag tcgctttttg aggggtatta tggtataatg
    30781 ggtgccaaga ggttttgaat gaaaaaattt tatgtaagtc caatttttcc tattctagta
    30841 ggattgattg cgtttggagt cttatccact ttcattattt ttgttaataa taatctgttg
    30901 acggttttaa ttttgtttct ttttgtagga ggctatgttt ttttatttaa gaaactgaga
    30961 gtgcattata caaggagtga tgtagaacag atacagtatg taaaccacca agcggaagaa
    31021 agtttgacat ctctattgga acaaatgcct gtaggtgtta tgaaattgaa tttatcttct
    31081 ggagaggttg agtggtttaa tccctatgct gaattgattt tgaccaagga agatggtgat
    31141 tttgatttag aagctgttca aacgattatc aaggcttcag taggaaatcc gtctacttat
    31201 gccaagcttg gtgagaagcg ttatgctgtt catatggatg cttcttccgg tgttttgtat
    31261 tttgtagatg tatccaggga acaagccata acagatgaat tggtaacaag tcgaccagtg
    31321 attgggattg tctctgtgga taattatgat gatttggagg atgcaacttc tgagtcagat
    31381 attagtcaaa tcaatagttt tgtagctaat tttatatcag agttttcaga aaaatacatg
    31441 atgttttctc gtcgggtaag tatggatcga ttttatctat ttactgacta cacggtgctt
    31501 gagggcttga tgaatgataa attttctgtt attgatgctt tcagagaaga gtcgaaacag
    31561 agacagttgc ccttgacctt aagtatggga ttttcttatg gcgatggaaa tcatgatgag
    31621 atagggaaag ttgctttgct caatttgaac ttggctgaag tacgtggtgg cgaccaggtg
    31681 gttgttaagg aaaacgacga aacgaaaaat ccagtttatt ttggtggtgg gtctgctgct
    31741 tcaatcaagc gtacacggac tcgtacgcgc gctatgatga cagctatttc agataagatt
    31801 cggagtgtag atcaggtttt tgtagtcggt cacaaaaatt tagacatgga tgctttgggc
    31861 tctgctgtag gtatgcagtt gttcgccagc aatgtgattg aaaatagcta tgctctttat
    31921 gatgaagaac aaatgtctcc agatattgaa cgagctgttt cattcataga aaaagaagga
    31981 gttacgaagt tgttgtctgt taaggatgca atggggatgg tgaccaatcg ttctttgttg
    32041 attcttgtag accattcaaa gacagcctta acattatcaa aagaatttta tgatttattt
    32101 acccaaacca ttgttattga ccaccataga agggatcagg attttccaga taatgcggtt
    32161 attacttata tcgaaagtgg tgcaagtagt gccagtgagt tggtaacgga attgattcag
    32221 ttccagaatt ctaagaaaaa tcgtttgagt cgtatgcaag caagtgtctt gatggctggt
    32281 atgatgttgg atactaaaaa tttcacctcg cgagtaacta gtcggacatt tgatgttgct
    32341 agctatctca gaacgcgcgg aagtgatagt attgctatcc aggaaatcgc tgcgacagat
    32401 tttgaagaat atcgtgaggt caatgaactt attttacagg ggcgtaaatt aggttcagat
    32461 gtactaatag cagaggctaa ggacacgaaa tgctatgata cagttgttat tagtaaggca
    32521 gcagatgcca tgttagccat gtcaggtatt gaagcgagtt ttgttcttgc gaagaataca
    32581 caaggattta tctctatctc agctcgaagt cgtagtaaac tgaatgtaca acggattatg
    32641 gaagagttag gcggtggagg ccactttaat ttggcagcag ctcaaattaa agatgtaacc
    32701 ttgtcagaag caggtgaaaa actgacagaa attgtattaa atgaaataaa ggaaaaggag
    32761 aaagaagaat gaaagtaatc tttttagcag atgttaaagg aaaaggtaaa aaaggcgaaa
    32821 ttaaggaagt accaacaggg tatgcgcaaa actttcttat caaaaagaat ctagccaaag
    32881 aagcgactgc tcaagctgta ggtgaacttc gtggtaaaca aaaatcggaa gaaaaagctc
    32941 acgctgagat gattgcagaa ggaaaagcaa ttaaagcaca acttgaagca gaagaaactg
    33001 ttgtagaatt tgttgaaaaa gttggtccag atggtcgtac ctttggttct attaccaata
    33061 agaagattgc agaagaattg caaaagcaat ttggaattaa gattgataaa cgtcatattc
    33121 aagtacaagc tccgattcga gcggttggtt tgattgatgt gccagtgaaa atctatcaag
    33181 atatcacaag tgtaatcaat cttcgtgtga aagaaggata agtttacacc ttcttgacaa
    33241 gattgtaaaa ggaagggaag tctgatggca gaagtagaag agttacgagt acaacctcaa
    33301 gatatcttag ctgagcaatc cgttttaggg gctatcttta ttgatgagag taaacttgtt
    33361 tttgtgcgag aatacattga gtctcgggac ttttttaagt atgcccatcg tttgattttc
    33421 caagccatgg tcgatttatc cgatcgtggt gatgccatag atgcaacaac ggttcgtact
    33481 atccttgata atcaaggtga tttacagaat attggtggct tgtcttactt ggttgagatt
    33541 gttaattctg tgccaacttc tgctaatgcg gagtattatg ctaagattgt tgcagaaaaa
    33601 gcaatgctac gtcgtttaat tgccaagttg acagagtctg tcaaccaagc ttacgaagcg
    33661 tcacaaccag ctgatgaaat tattgctcag gcagaaaaag ggttgattga tgtcagtgaa
    33721 aatgcaaatc gaagcgggtt taagaacatt cgagatgtgt tgaatctcaa ctttggaaat
    33781 ctggaagctc gctcgcaaca aacgaccgat attacaggta ttgcgacagg ttatcgtgat
    33841 ttggatcata tgacaacagg acttcatgag gaggagttga ttatcttagc agctcgtcca
    33901 gcagttggta agacagcatt tgccttgaat atcgctcaga atattgggac taagttggac
    33961 aaaacggttg ctattttttc actcgaaatg ggtgcggaaa gcttggtaga ccgtatgtta
    34021 gctgcagaag gcttggtgga gtcacattct atccgtacag ggcaattgac agatgaggag
    34081 tggcaaaaat atactattgc tcagggtaat ctagctaacg ccagtatcta tatcgatgat
    34141 acgccaggta ttcggattac agagattcgt tctcgttctc gtaaattggc tcaagaaact
    34201 ggaaatcttg gtttgatttt gatagactat ttgcaactta tcacgggaac tggtcgagaa
    34261 aatcgtcaac aagaagtttc tgaaatttct cgtcagttga aaatactagc caaggaattg
    34321 aaggttccag taatcgctct gagtcagctt tctcgtggtg tagaacaacg tcaggacaag
    34381 agaccggtct tgtctgatat tcgtgaatct gggtctattg agcaggacgc tgatatcgta
    34441 gcttttctct atcgcgatga ctactatgaa cgtggtggtg aagaagagga gggtatccca
    34501 aataataagg tggaagttat tatcgagaaa aaccgtagtg gagctcgtgg aacagtggaa
    34561 ttgattttcc aaaaagaata caataaattt tcaagtatct caaagaggga ggcataagat
    34621 gtcagatgca tttacagatg tagccaagat gaaaaaaatc aaagaagaaa tcaaggcaca
    34681 tgagggacaa gtcgtagaaa tgactttgga gaatggtcgt aagcgccaaa aaaatagatt
    34741 gggtaagcta attgaagttt atccatccct atttattgtg gagtttgggg atgtggaagg
    34801 agataaacaa gttaatgttt acgttgaatc ctttacttac tcagatattc ttacagaaaa
    34861 gaatttgatt cattatcttg actaaagtga gaaattttct cactttttct tttttctccg
    34921 aataatttag gtgaaggcaa tcatcgcttt atattatttt ttaaggagga agaatgaaaa
    34981 ttttaccgtt tatagcaaga ggaacaagtt attacttgaa gatgtcagtt aaaaagcttg
    35041 ttcctttttt agtagtagga ttgatgctag cagctggtga tagtgtctat gcctattcca
    35101 gaggaaatgg atcgattgcg cgtggggatg attatcctgc ttattataaa aatgggagcc
    35161 aggagattga tcagtggcgc atgtattctc gtcagtgtac ttcttttgta gcctttcgtt
    35221 tgagtaatgt caatggtttt gaaattccgg cagcttatgg aaatgcgaat gaatggggac
    35281 atcgtgctcg tcgggaaggt tatcgtgtag ataatacacc gacgattggt tccattactt
    35341 ggtctactgc aggaacttat ggtcatgttg cctgggtgtc aaatgtaatg ggagatcaga
    35401 ttgagattga ggaatataac tatggttata cagaatccta taataaacga attataaaag
    35461 caaacacgat gacaggattt attcatttta aagatttgga tggtggcagt gttgggaata
    35521 gtcaatcctc aacttcaaca ggcggaactc attattttaa gaccaagtct gctattaaaa
    35581 ctgaacccct agttagtgca actgtgattg attactatta tcctggagag aaggttcatt
    35641 atgatcaaat tctcgaaaaa gacggctaca agtggttgag ttatactgcc tataatggaa
    35701 gctatcgtta tgttcaattg gaggctgtga ataaaaatcc tctaggtaat tctgttcttt
    35761 cttcaacagg tggaactcat tattttaaga ccaagtctgc tatcaaaact gaacccctag
    35821 ttagtgcaac tgtgattgat tactattatc ctggggagaa ggttcattat gatcagatac
    35881 ttgaaaaaga cggctacaag tggttgagtt atacggctta taacggaagt cgtcgctata
    35941 tacagctaga gggagtgact tcttcacaaa attatcagaa tcaatcagga aatatctcta
    36001 gctatggatc caataatagt tcaactgtcg gttggaagaa aataaatggt agttggtatc
    36061 atttcaaatc aaatggttct aaatcaacag gatggctgaa agatggttct agctggtatt
    36121 atttgaaatt atctggtgaa atgcagacag gatggttaaa ggagaatggc tcgtggtatt
    36181 atctgggtag ttcaggggca atgaaaacag gctggtacca ggtctctggt aagtggtatt
    36241 attcttactc ttcaggcgcc ttagctgtta atacgacggt ggatggctac agagtaaaca
    36301 gtgatggaga acgagtatag aaaattggag taggagaaat ttcctgctct tttctgtaag
    36361 cagtttcctt gacatttttc ttattttgcg ctatcatata tacatataat atatgggagt
    36421 ctgtgtacag tctgagagga agtgttaaac ttcgaccgca cctgatctgg gtaatgccag
    36481 cggagggaac gatacttagt ctaattttgc accttttcca tgtatggtaa aggtttttct
    36541 ttttttaaaa aggaaaacga gaagaggagg ttcttatgaa agcaagcatt gccttgcaag
    36601 ttttacccct agcacagggg attgatcgga tagctgttat tgatcaggtc attgcttatc
    36661 tgcaaactca agaagtgacg atggtagtga caccatttga aacggtcttg gaaggggagt
    36721 ttgatgagct tatgcgcatt ctaaaagaag cgctggaagt ggcagggcag ggggcagaca
    36781 atgtcttttc caatgtcaaa ataaatgtag gagagatttt aagtattgat gagaaacttg
    36841 agaagtatac tgagacgaca cattagtcta ttgggctttc tcggagtctt gtcaatctgg
    36901 cagttagcag gttttcttaa acttctcccc aagtttatcc tgccgacacc tcttgaaatt
    36961 ctccagccct ttgttcgtga cagagaattt ctctggcacc atagctgggc gaccttgaga
    37021 gtggctttac tggggctgat tttgggagtt ttgattgcct gtcttatggc tgtactcatg
    37081 gatagtttga cttggttcaa tgacctgatt taccctatga tggtggtcat tcagaccatt
    37141 ccgaccattg ccatagctcc tatcctggtc ttgtggctag gttatgggat tttgcccaag
    37201 attgtcttga ttatcttaac aacaaccttt cccatcatcg ttagtatttt ggacggtttt
    37261 aggcattgtg acaaggatat gctgaccttg tttagtctga tgcgagcaaa cccttggcaa
    37321 atcctgtggc attttaaaat cccggttagc ctgccttact tttatgcagg tctgagggtc
    37381 agtgtctcct acgcctttat cacaactgtg gtatctgagt ggttgggagg ttttgagggg
    37441 cttggtgttt atatgattca gtccaagaaa ttgtttcagt atgataccat gtttgccatt
    37501 attattctgg tgtcgattat cagtcttttg ggtatgaagc tggtcgatat cagtgaaaaa
    37561 tatgtgatta aatggaaacg tacttaaaat agagcgtttt tgaaaaagaa aagaggaaat
    37621 caaaatgaag aaaacatgga aagtgttttt aacgcttgta acagctcttg tagctgttgt
    37681 gcttgtggcc tgtggtcaag gaactgcttc taaagacaac aaagaggcag aacttaagaa
    37741 ggttgacttt atcctagact ggacaccaaa taccaaccac acagggcttt atgttgccaa
    37801 ggaaaaaggt tatttcaaag aagctggagt ggatgttgat ttgaaattgc caccagaaga
    37861 aagttcttct gacttggtta tcaacggaaa ggcaccattt gcagtgtatt tccaagacta
    37921 catggctaag aaattggaaa aaggagcagg aatcactgcc gttgcagcta ttgttgaaca
    37981 caatacatca ggaatcatct ctcgtaaatc tgataatgta agcagtccaa aagacttggt
    38041 tggtaagaaa tatgggacat ggaatgaccc aactgaactt gctatgttga aaaccttggt
    38101 agaatctcaa ggtggagact ttgagaaggt tgaaaaagta ccaaataacg actcaaactc
    38161 aatcacaccg attgccaatg gcgtctttga tactgcttgg atttactacg gttgggatgg
    38221 tatccttgct aaatctcaag gtgtagatgc taacttcatg tacttgaaag actatgtcaa
    38281 ggagtttgac tactattcac cagttatcat cgcaaacaac gactatctga aagataacaa
    38341 agaagaagct cgcaaagtca tccaagccat caaaaaaggc taccaatatg ctatggaaca
    38401 tccagaagaa gctgcagata ttctcatcaa gaatgcacct gaactcaagg aaaaacgtga
    38461 ctttgtcatc gaatctcaaa aatacttgtc aaaagaatac gcaagcgaca aggaaaaatg
    38521 gggtcaattt gacgcagctc gctggaatgc tttctacaaa tgggataaag aaaatggtat
    38581 ccttaaagaa gacttgacag acaaaggctt caccaatgaa tttgtgaaat aatgacagaa
    38641 attagactag agcacgtcag ttatgcctat ggtcaggaga ggattttaga ggatatcaac
    38701 ctacaggtga cttcaggcga agtggtttcc atcctaggcc caagtggtgt tggaaagacc
    38761 accctcttta atctaatcgc tgggatttta gaagttcagt cagggagaat tgtccttgat
    38821 ggtgaagaaa atccccaggg gcgcgtgagt tatatgttgc aaaaggatct gctcttggag
    38881 cacaagacgg tgcttggaaa tatcattctg cccctcttga ttcaaaaggt ggataaggca
    38941 gaagctattt cccgagcgga taaaattctt gcgaccttcc agctgacagc tgtaagagac
    39001 aagtatcctc atgaacttag cggtgggatg cgccagcgtg tagccttact ccggacctac
    39061 ctttttgggc acaagctctt tctcttagat gaggccttta gcgccttgga tgagatgaca
    39121 aagatggaac tccacgcttg gtaccttgag attcacaagc agttgcagct aacaaccttg
    39181 attattactc acagtatcga ggaggccctc aatctcagtg accgcatcta tatcttgaaa
    39241 aatcgccctg ggcagattgt ttcagaaatt aaactagatt ggtctgaaga tgaggacaag
    39301 gaagttcaaa agattgccta caaacgtcaa atcttggcag aattaggctt agataagtag
    39361 aaaaataggg agttggtgaa gattatcctt taccagcgcc ctttttcttt taaaaatgag
    39421 aaaatttcgg tataatagtc aaacaaggtc aaggtttaaa gagagaggtg ggtttgttat
    39481 gagatttaaa aatacatcgg atcatattga ggcctacatc aaggcgattt tagatcaatc
    39541 tggtatcgtg gagttgcaac ggagtcagtt ggcagatacc tttcaggttg ttcctagtca
    39601 gattaactac gtgatcaaga cacgctttac ggaaagtaga ggctacttgg ttgaaagtaa
    39661 gcgtggtggc ggaggctaca ttcgtatagg acggattgag ttttctagtc atcatgaaat
    39721 gctccgggag ctgctttact cgattggtga gcgagtcagt caagaaattt atgaggatat
    39781 tctccagctt ttggttgagc aggaattgat gaccaagcag gagatgaatt tgctagaatc
    39841 agtagctttg gatcgcgttt taggagaaga agctccagtt gttcgagcaa acatgctacg
    39901 tcagatcata caagaggtag atagaaaagg gaagtaagat gaactattca aaagcattga
    39961 atgaatgtat cgaaagtgcc tacatggttg ctggacattt tggagctcgt tatctagagt
    40021 cgtggcactt gttgattgcc atgtctaatc acagttatag tgtagcaggg gcaactttaa
    40081 atgattatcc gtatgagatg gaccgtttag aagaggtggc tttggaactg actgaaacgg
    40141 actatagcca ggatgaaacc tttacggaat tgccgttctc ccgtcgtttg caggttcttt
    40201 ttgacgaagc agagtatgta gcgtcagtgg tccatgctaa ggtgctaggg acagagcacg
    40261 tcttctatgc gattttgcat gatggcaatg ccttggcaac tcgtatcttg gagagggctg
    40321 gtttttctta tgaagacaag aaagatcagg tcaagattgc tacccttcgt cgaaatttag
    40381 aagaacgtgc aggctggact cgtgaagatc tcaaggcttt acgccaacgc catcgtacag
    40441 tagctgacaa gcaaaattct atggccaata tgatgggcat gccgcagact cctagtggtg
    40501 gtctcgagga ctatacgcat gatttgacag agcaagcgcg ttctggcaag ttagaaccag
    40561 tcatcggtcg ggacaaggaa atctcacgta tgattcaaat attgagccgt aagactaaga
    40621 acaaccctgt cttggttggg gatgctggtg tcgggaaaac agctctggcc cttggtcttg
    40681 ctcagcgtat tgctagtggt gacgtgcctg cggaaatggc taagatgcgc gtgttagaac
    40741 ttgatttgat gaatgtcgtt gcagggacac gcttccgtgg tgactttgaa gaacgcatga
    40801 ataatatcat caaggatatt gaagaagatg gccaagtcat cctctttatc gatgaactcc
    40861 acaccatcat gggttctggt agcgggattg attcgactct ggatgcggcc aatatcttga
    40921 aaccagcctt ggcgcgtgga actttgagaa cggttggtgc caccactcag gaagaatatc
    40981 aaaaacatat cgaaaaagat gcggctcttt ctcgtcgttt cgctaaagtg acgattgaag
    41041 aaccaagtgt ggcagatagt atgactattt tacaaggttt gaaggcgact tatgagaaac
    41101 atcaccgtgt acaaatcaca gatgaagcgg ttgaaacagc ggttaagatg gctcatcgtt
    41161 atttaaccag tcgtcacttg ccagactctg ctatcgacct cttggacgaa gcagcagcaa
    41221 cagtgcaaaa taaggcaaag tatgtaaaag cagacgattc agatttgagt ccagctgaca
    41281 aggccctgat ggatggcaag tggaaacagg cagcccagct aatcgcaaaa gaagaggaag
    41341 tacctgtcta caaagacttg gtgacagagt ctgatatttt gaccaccttg agtcgcttgt
    41401 caggaatccc agttcaaaaa ctgactcaga ctgacgctaa gaaatatcta aatcttgaag
    41461 cagaactcca taaacgggtt atcggtcaag atcaagctgt ttcaagtatt agtcgtgcga
    41521 ttcgccgtaa tcagtcagga attcgcagtc acaagcgtcc gatcggttcc tttatgttcc
    41581 taggacccac aggtgtcggt aagaccgagt tggccaaggc tttggcagaa gttctctttg
    41641 atgacgaatc agcccttatc cgctttgata tgagtgagta tatggagaaa ttcgcagcca
    41701 gccgtctaaa tggagctcct ccaggctatg tgggttacga agaaggtggg gagttgacag
    41761 agaaggttcg caataaaccc tattccgttc tcctctttga tgaggtagag aaggctcacc
    41821 cagatatctt taatgttctc ttgcaggttc tggatgacgg tgtcttgaca gatagcaagg
    41881 gacgcaaggt cgatttttca aataccatta tcattatgac atcgaaccta ggtgcgactg
    41941 cccttcgtga tgataagact gttggttttg gggctaagga tattcgtttt gaccaggaaa
    42001 atatggaaaa acgcatgttt gaagaactga aaaaagctta tagaccggaa ttcatcaacc
    42061 gtattgatga gaaggtggtc ttccatagcc tatctagtga ccatatgcag gaagtggtga
    42121 agattatggt caagccttta gtggcaagtt tggctgaaaa aggcattgac ttgaaattac
    42181 aagcttcagc tctgaaattg ttagcaaatc aaggatatga cccagagatg ggagctcgcc
    42241 cacttcgcag aaccctgcaa acagaagtgg aggacaagtt ggcagaactt cttctcaagg
    42301 gagatttagt ggcaggcagc acacttaaga ttggtgtcaa agcaggccag ttaaaatttg
    42361 atattgcata aaagaataaa agtaccagca tctgaccata agtcacagtg gagtgaaact
    42421 caatgaaaat caaagagcaa actaggcagc tagccgcagg ttgctcaaaa cactggtttg
    42481 aggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtataa gctgcaagat
    42541 gaatgatttt cttgtattga cgttgttgtt gacaaaaagt agcggataaa tgaaatccat
    42601 tccattatca tagatgatag gctggtagga aattttcaaa tagcatacag gaaatagatg
    42661 tatggagttc tggtagtaga aagggagaga gatgaacatt ttagttgcag atgacgagga
    42721 aatgattaga gaaggaattg cagcatttct gacagaagag ggttatcatg tcattatggc
    42781 taaggatgga caagaggtct tggaaaaatt tcaagatctc cctatccatc tcatggtact
    42841 ggatttaatg atgcctagga agagtggttt tgaagtgtta aaagaaatca atcaaaagca
    42901 cgatattcct gtcatcgtct tgagtgctct gggagatgaa actactcagt cacaggtatt
    42961 tgatctctat gctgatgatc atgtgacaaa acctttttct ttggtactgc ttgtcaagcg
    43021 tattaaggcg cttatcagac gttactacgt catagaggat ctttggcgat atcaggatgt
    43081 aacagtggat tttacctctt acaaagcaca ttataaaaat gaagaaattg atctcaaacc
    43141 aaaggaatta ctggtactaa agtgtttgat tcagcataaa aatcaagttt taagtagaga
    43201 gcagatattg gaagaaattt caaaagatgt agctgattta ccttgtgata gggtcgttga
    43261 tgtctatatt cgtactcttc gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa
    43321 tgttgggtat aagattagct tatgataaaa aatcctaaat tattaaccaa gtctttttta
    43381 agaagttttg caattctagg tggtgttggt ctagtcattc atatagctat ttatttgacc
    43441 tttccttttt attatattca actggagggg gaaaagttta atgagagcgc aagagtgttt
    43501 acggagtatt taaagactaa gacatctgat gaaattccaa gcttactcca gtcttattca
    43561 aagtccttga ccatatctgc tcaccttaaa agagatattg tagataagcg gctccctctt
    43621 gtgcatgact tggatattaa agatggaaag ctatcaaatt atatcgtgat gttagatatg
    43681 tctgttagta cagcagatgg taaacaggta accgtgcaat ttgttcacgg ggtggatgtc
    43741 tacaaagaag caaagaatat tttgcttttg tatctcccat atacattttt ggttacaatt
    43801 gctttttcct ttgttttttc ttatttttat actaaacgct tgctcaatcc tcttttttac
    43861 atttcagaag tgactagtaa aatgcaagat ttggatgaca atattcgttt tgatgaaagt
    43921 aggaaagatg aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg
    43981 aaggttattc atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag
    44041 gtttcctttg tccgcggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt
    44101 atcctagaga atatgcagca taatattgga gattacaaag atcatccaaa atatattgca
    44161 aagagtataa ataagattga ccagatgagc cacttattgg aagaagtact ggagtcttct
    44221 aaattccaag agtggacaga gtgtcgtgag accttgactg ttaagccagt tttagtagat
    44281 attttatcac gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg
    44341 acagatgcta ccagggtcgt catgagtctt agggcattgg ataaggtttt gacaaacctg
    44401 attagtaatg caattaaata ttcagataaa aatgggcgtg taatcatatc cgagcaagat
    44461 ggctatctct ctatcaaaaa tacatgtgcg cctctaagtg accaagaact agaacattta
    44521 tttgatatat tctatcattc tcaaatcgtg acagataagg atgaaagttc cggtttgggt
    44581 ctttacattg tgaataatat tttagaaagc tatcaaatgg attatagttt tctcccttat
    44641 gaacacggta tggaatttaa gattagcttg tagacagatt agttttttat taaagttcac
    44701 atagggttaa cataagtgta ttattcttta tatagataaa aatatagata aaagaaagga
    44761 tactaatatg gtattagcga ttattttagt aatattcctt attcgattga tttttttaaa
    44821 gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat ttggagttga
    44881 gaatacaaaa cgattaacgt tggctcatat tgttttttat ctctcttgcc tcgttgaagc
    44941 aatggtgcat aagacaatgt ttgatggtat gagcatggtt ggtttagtct tgcttatttt
    45001 ttctatgctg atgttgatgt tggtgattca cttgttggga gatatttgga cagtgaagct
    45061 tatgcttgtc aataatcaca aatatgtaga tcatatctta tttaggacag taaaacatcc
    45121 taattacttt ttaaatatcc ttcctgagtt gattggcttg accttgttga gtcatgccta
    45181 tatgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac gaatagctga
    45241 agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga gataaataca
    45301 aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag aaaaaatata
    45361 gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt caattcgtaa
    45421 atttagtatt ggagtagcta gtgtagctgt tgccagtctt gttatgggaa gtgtggttca
    45481 tgcgacagag aaggaggtaa ctacccaagt acccacttat tctaatatgg caaagacaga
    45541 acataggaaa gctgctaaac aagtcgtcga tgaatatata gaaaaaatgt tgagggagat
    45601 tcaattagat agaagaaaac atacccaaaa tttcgccttc aacatgaagt tgagcgcaat
    45661 taaaacggag tatttgtatg gattaaaaga gaagtcggaa gctgagttgc cgtcatcgga
    45721 agctgagttg ccgtcagaag taaaagcaaa gttagacgca gcttttgagc agtttaaaaa
    45781 agatacattg aaactaggag aaaaggtagc agaagctgag aagaaggttg cagaagctga
    45841 gaaaaaagcc aaggctcaaa aagaagaaga tcgccgtaac tacccaacca ttacttacaa
    45901 aacgcttgac cttgaaattg ctgagtccga tgtggaagtt aaaaaagcgg agcttgaact
    45961 attgaaagag gaagctaaaa ctcgaaacaa ggacacaatt aagcaagcaa aagcgaaagt
    46021 tgagagtaaa caagctgagg ctacaaggtt agaaaaaatc aagacagatc gtaaaaaagc
    46081 agaagaagaa gctaaacgaa aagcagcaga agaagataaa gttaaagata aactaaagag
    46141 gcggacaaaa cgagcagttc ctggagagcc agcaacacct gataaaaaag aaaatggtgc
    46201 gaagtcttca gattctagcg taggtgaaga aactcttcca agcccatccc tgaaaccaga
    46261 aaaaaaggtt gcagaagctg agaagaaggt tgcagaagct gagaaaaaag ccaaggatca
    46321 aaaagaagaa gatcgccgta actacccaac caatacttac aaaacgcttg aacttgaaat
    46381 tgctgagtcc gatgtgaaag ttaaagaagc ggagcttgaa ctagtaaaag aggaagctaa
    46441 ggaatctcga aacgaggaaa aagttaagca agcaaaagcg aaagttgaga gtaaacaagc
    46501 tgaggctaca aggttagaaa aaatcaagac agatcgtaaa aaagcagaag aagaagctaa
    46561 acgaaaagca gcagaagaag ataaagttaa agaaaaacca gctgaacaac cacaaccagc
    46621 gccggctcct caaccagaaa aaccagctcc agctccaaaa ccagagaatc cagctgaaca
    46681 accaaaagca gaaaaaccag ctgatcaaca agctgaagaa gactatgctc gtagatcaga
    46741 agaagaatat aatcgcttga ctcaacagca accgccaaaa actgaaaaac cagcacaacc
    46801 atctactcca aaaacaggct ggaaacaaga aaacggtatg tggtacttct acaatactga
    46861 tggttcaatg gcgacaggat ggctccaaaa caatggctca tggtactacc tcaacagcaa
    46921 tggcgctatg gcgacaggat ggctccaaaa caatggttca tggtactatc taaacgctaa
    46981 tggttcaatg gcaacaggat ggctccaaaa caatggttca tggtactacc tcaacgctaa
    47041 tggttc
//
LOCUS       DAVLHM010000012        45537 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLHM010000012 DAVLHM010000000
VERSION     DAVLHM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.012"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..311)
                     /locus_tag="VXE45_000694"
                     /pseudo
     CDS             complement(1..311)
                     /locus_tag="VXE45_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(406..591)
                     /locus_tag="VXE45_000695"
                     /pseudo
     CDS             complement(406..591)
                     /locus_tag="VXE45_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            619..846
                     /locus_tag="VXE45_000696"
     CDS             619..846
                     /locus_tag="VXE45_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0788772.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            922..1474
                     /locus_tag="VXE45_000697"
                     /pseudo
     CDS             922..1474
                     /locus_tag="VXE45_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2058..2534
                     /locus_tag="VXE45_000698"
     CDS             2058..2534
                     /locus_tag="VXE45_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0788773.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            2572..2877
                     /locus_tag="VXE45_000699"
     CDS             2572..2877
                     /locus_tag="VXE45_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0788774.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            2925..4400
                     /locus_tag="VXE45_000700"
     CDS             2925..4400
                     /locus_tag="VXE45_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0788775.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            4426..4503
                     /locus_tag="VXE45_000701"
                     /pseudo
     CDS             4426..4503
                     /locus_tag="VXE45_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4705..11406
                     /locus_tag="VXE45_000702"
     CDS             4705..11406
                     /locus_tag="VXE45_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0788776.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIENRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLYKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     VPKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSFPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPSTGSAASQAAVAAGLTLLGLSAGLVVTKGKKED"
     gene            complement(11654..12510)
                     /locus_tag="VXE45_000703"
                     /pseudo
     CDS             complement(11654..12510)
                     /locus_tag="VXE45_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12720..13079)
                     /locus_tag="VXE45_000704"
     CDS             complement(12720..13079)
                     /locus_tag="VXE45_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0788777.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            13102..13680
                     /locus_tag="VXE45_000705"
     CDS             13102..13680
                     /locus_tag="VXE45_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846832.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEV0788778.1"
                     /translation="METRNRGIYRKVRLLRLWVIFVIMKVMKSYNTLNDYYRKLFGEK
                     TFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKW
                     PDVQKYLVYFQNFTNTHEKVEVVRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAE
                     LSECMHVTVELGLQTTYEATSDLINRAHSYEL"
     gene            13681..14127
                     /locus_tag="VXE45_000706"
     CDS             13681..14127
                     /locus_tag="VXE45_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEV0788779.1"
                     /translation="METVKRLRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTNNDI
                     QGIKLHLLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAP
                     RDMLLGLMWSLNKWEALNSIEMEMRRRGSVQGCKAVKQEFENEKTT"
     gene            14111..14668
                     /locus_tag="VXE45_000707"
     CDS             14111..14668
                     /locus_tag="VXE45_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0788780.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            14661..14915
                     /locus_tag="VXE45_000708"
     CDS             14661..14915
                     /locus_tag="VXE45_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788781.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            14927..16981
                     /locus_tag="VXE45_000709"
     CDS             14927..16981
                     /locus_tag="VXE45_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0788782.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            17160..18020
                     /locus_tag="VXE45_000710"
     CDS             17160..18020
                     /locus_tag="VXE45_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0788783.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            18231..18941
                     /gene="ccdA2"
                     /locus_tag="VXE45_000711"
     CDS             18231..18941
                     /gene="ccdA2"
                     /locus_tag="VXE45_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0788784.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            18961..19527
                     /locus_tag="VXE45_000712"
     CDS             18961..19527
                     /locus_tag="VXE45_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0788785.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            19538..20650
                     /gene="msrB"
                     /locus_tag="VXE45_000713"
     CDS             19538..20650
                     /gene="msrB"
                     /locus_tag="VXE45_000713"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0788786.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            21008..21745
                     /locus_tag="VXE45_000714"
     CDS             21008..21745
                     /locus_tag="VXE45_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0788787.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            21742..23433
                     /locus_tag="VXE45_000715"
     CDS             21742..23433
                     /locus_tag="VXE45_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0788788.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            23549..24112
                     /locus_tag="VXE45_000716"
     CDS             23549..24112
                     /locus_tag="VXE45_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0788789.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            24134..30076
                     /locus_tag="VXE45_000717"
     CDS             24134..30076
                     /locus_tag="VXE45_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0788790.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEDTQPEVVETKDEAANQP
                     VEEPKVETPAVEKQTEPTEEPKVEQVGEPVEPREDEKAPVSPEKQPEAPEEEKTAEET
                     PKQEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASE
                     PVKQPEVNSETKAEKVAANTDAKQSEVNSETASLKTAISGLNTDKVELENQLKIAQGK
                     TETDFSMESWTVLSTAKNKAQEVKDNGTATQEQINEAEKSLKTALADLSVDKTALGSA
                     IDTATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATIEKLVELS
                     EKPRLTLSIEKRDIDRKVTVTYTLENPANTQIKSITATLKKGEEVVKDFVLTEENLKT
                     NHLTALFEKLDYYKEYTLSTDMVYNRGNDDETESISEELIQLNLKKLELKDIQTVSLM
                     KFENGQESQVTHLSDKPTDLSKLYLKVTSSTSKDAVLAVSSIEEEIVENKKIFKIHAD
                     TPELVVRKKDGSLSKGFDYYMERVIPHDGDIYYDFKDLISAMTSNPTGTFILGRDISS
                     RNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIFDLEYPLFDTIKSGVVKDIDFKHVNM
                     VFPDSNQGDNVATIARVIKDKTKIENVNVEGYLEGRDHVAGLVNNLEGNSEIENISFT
                     GKIKSKGGNSITAGIAGRNILSRVKRAYVNANIEVLGSTNSSMLVAVNGTTLNASGGW
                     GAWGRLTESVAKGTLEIKRSGQAGGVTATVWPYGAIDKVVSYAKVTKGKELFGSDGDL
                     NNNWFMQKINNIFGVQGISSGDSGNDSKFKRISEEEAKQKVASYNITAPNLMSDSSLL
                     VDRLNESWKNTDQFESIQDYQSQNQLIYQNLTKFTPYYNKEFIVHEGNALTPEQEILK
                     TKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGSQKRYKVTSTGKFSITNLPEYQVEDL
                     NVVYTSEHIVHPLDSSLINNLVEELKKVELYTESTYQVLGIDKDNANKLNRTKRLFLD
                     ESLDAVKTQLPTFVKTMFENEWLHINGESSGAVAALRQKIMDNKTAILLALTYINRYY
                     DVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRLGSSGENRLKGSENAETFKQLFASET
                     KQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDYIQFEERPSLVEEIKDAKYRVYDNLT
                     APYYQGYILPLLTLKNTHLAILSNYSTMTFVSREKRPNWKNEDFDKWVKYVATAHRNH
                     VDTWYKILPDNIKGKMVKENVTAVWEGLSIPGSEWVDQNAVDRKGRDYAPAREFFNLV
                     GGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSEYGISVFTHELTHVNDTWIYLGGYGR
                     RENMGPEAYAQGLFQSPVPGQPGWGALGLNMAFERKNDGDLIYNASPTQFENRKELDS
                     YMKNYNDTLMMVDYLEGDAVISKGKEAITKWFKKVEPKVVSQTAQYDTVRQLTAEEKE
                     KLSVSSVDDLVDQGLMSDRAVGNNTYNPADFETSYIAIDYMTGIYGGGKNSVGSPGAL
                     MFKHNTFRMWGYYGFEEGVLGYASNKFKQASRDEGHAGLSDNFIISKISKGEFLTMEA
                     FKKGYFKKVVEELKTKGIRPVTINQKTYSTFEELQEGFKQAVERDLKKNQLDERETRN
                     FKFQVFRQLLQQTDSFKTSIFR"
     gene            30137..31858
                     /gene="pabB"
                     /locus_tag="VXE45_000718"
     CDS             30137..31858
                     /gene="pabB"
                     /locus_tag="VXE45_000718"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0788791.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            31859..32476
                     /locus_tag="VXE45_000719"
     CDS             31859..32476
                     /locus_tag="VXE45_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0788792.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SFMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            32526..33524
                     /locus_tag="VXE45_000720"
     CDS             32526..33524
                     /locus_tag="VXE45_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0788793.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEREPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            33651..34610
                     /locus_tag="VXE45_000721"
     CDS             33651..34610
                     /locus_tag="VXE45_000721"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0788794.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            34707..35546
                     /locus_tag="VXE45_000722"
     CDS             34707..35546
                     /locus_tag="VXE45_000722"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0788795.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(35594..35764)
                     /locus_tag="VXE45_000723"
     CDS             complement(35594..35764)
                     /locus_tag="VXE45_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0788796.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            35885..36769
                     /gene="miaA"
                     /locus_tag="VXE45_000724"
     CDS             35885..36769
                     /gene="miaA"
                     /locus_tag="VXE45_000724"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0788797.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            36762..38000
                     /gene="hflX"
                     /locus_tag="VXE45_000725"
     CDS             36762..38000
                     /gene="hflX"
                     /locus_tag="VXE45_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0788798.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            37993..38616
                     /locus_tag="VXE45_000726"
     CDS             37993..38616
                     /locus_tag="VXE45_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0788799.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            38631..39560
                     /locus_tag="VXE45_000727"
     CDS             38631..39560
                     /locus_tag="VXE45_000727"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0788800.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            39581..40336
                     /locus_tag="VXE45_000728"
     CDS             39581..40336
                     /locus_tag="VXE45_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0788801.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40390..41298)
                     /locus_tag="VXE45_000729"
     CDS             complement(40390..41298)
                     /locus_tag="VXE45_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0788802.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            41362..41631
                     /locus_tag="VXE45_000730"
     CDS             41362..41631
                     /locus_tag="VXE45_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0788803.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            41631..42011
                     /locus_tag="VXE45_000731"
     CDS             41631..42011
                     /locus_tag="VXE45_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0788804.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            42129..42326
                     /locus_tag="VXE45_000732"
     CDS             42129..42326
                     /locus_tag="VXE45_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788805.1"
                     /translation="MGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKIL
                     NILGIVISVVNWIVAIALIFR"
     gene            complement(42366..43091)
                     /locus_tag="VXE45_000733"
     CDS             complement(42366..43091)
                     /locus_tag="VXE45_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0788806.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            43253..45094
                     /gene="typA"
                     /locus_tag="VXE45_000734"
     CDS             43253..45094
                     /gene="typA"
                     /locus_tag="VXE45_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0788807.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            45114..45368
                     /locus_tag="VXE45_000735"
     CDS             45114..45368
                     /locus_tag="VXE45_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0788808.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        13940 a         8393 c        10120 g        13084 t
ORIGIN      
        1 tttgatattc agagcgatga aaatccgttt tttgaagttt tcaaagtttc gaaaaccaaa
       61 ggcattgcgc ttgataagtt tgatgagatt attggtcgct tccagtttgg cattagaata
      121 gtgtagttga agggcattga caatcttctc tttatctttg aggaaggttt tagaggatga
      181 acctgattca gattgtcctc aatgagtccg aaaaatttgt caggctcctt attctgaaag
      241 tgaaaaagca agagttgata gagattatag tggtgtttca agtcttctga atagctcaaa
      301 agtttatcta tagtagattg aaactagaat agtacacctc tgcttctaaa acattgttag
      361 aaatcgattt gactgtcctg aatgatttgt cctgttatta tttcatttta ctataaatcc
      421 acgtttacga atctctttcc acacttgttc aatggggttc atctctggtg tgtatggagg
      481 aataaatgca aaaccaatat tagtcggaat ctttaaggta cttgatttat gccatatagc
      541 attgtccata acgagtaaaa gataatcatc tggataagct tgtgaaagct cctattccta
      601 aagccccttt ataacctctt gcgagagaga ctattgactc agcccttact tcatgcggat
      661 gaaacttctt atcgggttct agagagtcat agccatctga cctactattg gacctttttg
      721 tctgggaaag ttgagaatca agcaatcacg ctgtaccatc atgatcagag tcggagtggt
      781 tcggtagtac aagaattcct aggagattat tctggctatg ttcattgtga tatgttgcgg
      841 cagtaactta ggactttagt cctctagttc tgcctatgcg atagcagtcc aaggtttagg
      901 agcaaggcga cgctaagctt ggtaaactgc gaactgctag aagcttatcg tcaactggaa
      961 gaagctgaac ttgttggatg ttgggcgcat gtgagaagga aattttttga agcgaccccc
     1021 aagcaagcag ataaatcatc cttaggagct aaaggtttag cttattgtga tcagttattt
     1081 tccttggaaa gagactggga ggctttgcca gctgatgaac gactacagaa acgtcaagaa
     1141 catctccagc ccctaatgga agacttcttt gcttggtgtc gccgtcagtc agttttagca
     1201 ggttcaaaac taggaagggc aattgaatac agcctcaagt atgaagaaac ctttaagact
     1261 attttgaaag acggacatct ggtcctttcc aataatctag ctgaacgcgc cattaaatca
     1321 ttggttatgg gacggagtaa aagagtccag tggactcttt tagcctgagc tcagtttaaa
     1381 aaagcgaggg tggttatttt ctcaaagttt tgaaggagct aaagcaagag ctattattat
     1441 gagcttgttg gaaacagcta aacgtcatca attatagtgc gttgaatcta taacagtacg
     1501 catcgactgc taaaacattt ctataaatca attttccttt cctaatcgat ttgttcatat
     1561 cttatttcaa tccattataa atagcgagaa atatctatcc tatcttctag aatgtcttcc
     1621 aaacgaggaa actctcgtaa acaaagaggt tttagaggcc tatttaccat ggactaaagt
     1681 tgtacaagaa aagtgcaaat aagaaatctc cagattagga actatccgtg agttcactaa
     1741 tctggagatt tttcaataga cttcgttatt gggcggttac gatatgatca ctgacttcgt
     1801 cagtcttatc tacaacctca aaactgtgtt ttgagcaacc tgcggctagc ttcctagttt
     1861 gctctttgat tttcattgag tattagaaca gaaaaaatac ttggagtatt tgtttgtgtg
     1921 tttattttta tataacaaac tataaacaaa acaaaaatat aaaaaaagag acaaaaaaag
     1981 aacagaaagc aattgacaac ggtttcatat agtgttatac ttatggcata aagttaatgg
     2041 aaagaaggga aaaacttatg gtattagatt atttctttga caaaaacctt gtgttttgct
     2101 tagaagcgga taatcaagaa caactctttg atcaggttgc aactttattg gaagaacgag
     2161 aaattgtcac tccaacttat cgtgaagcct tgatcacgcg tgaaaagtca tttccaactg
     2221 gtttagatat ggaatttcta ggaaaggact tgccaaatgt agcgattcct catacagata
     2281 ttgttcataa tctagctgag aaagtggtgg ttgttcgatt agaaaaacca gtaacttttc
     2341 acaatatgat agctcctgat aaggaagtag aagtatccct actcttcttt attattaaca
     2401 attcaagttc aagtcaaaca aatattctgg ctcagttgat ggactttttc acaggaaatg
     2461 gacatcttga agacctatca aaaatttccg aaccagaaaa actttatgct tacattgctg
     2521 aagcaaccgc ttaatcttgt ctattaaaaa ataaaatcgg aggaaatcca aatgattaaa
     2581 attcttgctg cctgcggtgc aggtgttaac tcaagtcacc aaattaaaag tgctctagaa
     2641 gaagaacttt caaaccgtgg ttatgatgtt cactgtgatg cagtcatggt gaaagatgta
     2701 aacgaagacc ttatgaaagg ttacgatatc tttacaccaa tcgctgcaac agaccttggt
     2761 tttgaaccag gtatcccagt tatcgaagct gggccaatct tattccgtat cccagcaatg
     2821 agcgctccag tatttgacaa tattgaagca gctattaaag aacacggatt aagctaattc
     2881 taatttgtta acattcatat aacataaaaa agggaggaac tgttatggat gcaatctttg
     2941 acctaatcgg aaaggttttc aatcccattt tagaaatggg tggacctgtc atcatgttaa
     3001 tcattttgac agtattggct ttactttttg gagtgaaatt ctccaaagcg cttgaaggtg
     3061 gtatcaaact tgccatcgct cttacaggta tcggtgctat catcggtatg ctaaatggtg
     3121 ctttctcagc atcacttgca aaattcgttg aaaacactgg tatccaattg agtattaccg
     3181 acgttggttg ggcaccactc gcaacaatca cttggggttc tgcttggaca ctatacttct
     3241 tgctcatcat gttgattgtc aacatagtga tgctagctat gaagaaaaca gatacacttg
     3301 acgttgatat ctttgatatc tggcacttgt ctatcacagg tctcttgatt aaatggtatg
     3361 ctgataacaa tggtgtgagt caaggggttt cactctttat tgctacagca gctatcgtcc
     3421 ttgtcggtgt gttgaaaatt atcaactctg acttgatgaa acctacattt gatgaccttc
     3481 ttaacgcccc aagttcatca ccaatgacat caactcacat gaactacatg atgaacccag
     3541 ttatcatggt tttggataag atttttgaaa aattcttccc aggccttgat aaatatgact
     3601 ttgatgctgc taaattgaac aagaaaatcg gtttctgggg atctaaattc ttcatcggtt
     3661 tcatccttgg tatcgttatc ggtattatgg gaactccaca tccaattgca ggtgttgcag
     3721 atgcagataa atggcgtctt gttatcaaag gatggttgtc tcttggtttg actgccggtg
     3781 tatctttgga actcttctca cttatcggtt catggttcat cgcagccgta gaaccactat
     3841 cacaaggtat tacaaacgtt gctactaaac gtcttcaagg acgtaaattc aatatcggtc
     3901 ttgactggcc attcatcgct ggtcgtgctg aaatctgggc ttgtgccaac gtacttgcac
     3961 caatcatgtt gattgaagca gtgcttcttt caaaagttgg aaatggtatc ttgccacttg
     4021 caggtatcat cgctatgggt gttactccag ctctcttggt tgtaactcgt ggtaaattgc
     4081 tccgtatgat tatcttcgga acactcttgt tgccactctt ccttctttca ggtacactta
     4141 ttgcaccatt tgcaacagaa cttgctaaag gtgtaggtgc cttcccagaa ggtgtgagcc
     4201 aaactcaatt gattactcac tctactcttg aaggaccaat cgaaaaactt cttggttgga
     4261 caattggtaa cactacaact ggtgatatca aagcaatcct tggtgcagta gtcttccttg
     4321 tattctatat cggtatcttt gcttggtaca gaaaacaaat gatcaaacgt aacgaagagt
     4381 acgcagcaaa agcaaaataa tgcgctccta taaaatataa actcaatgaa aatcaaagag
     4441 caaactagga aactagccac aggttgctca aaacacagtt ttgaggttgt agataagact
     4501 gacgaagtca gctcaaaaca tggttttgag gttgtagatg aaactgacga agtcagtaat
     4561 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
     4621 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggcagtag ctaactgcac
     4681 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
     4741 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
     4801 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
     4861 actgctgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
     4921 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
     4981 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
     5041 ccggaagaaa aagctccaag gatagaatca caagcttcaa gtcaagaaaa accgctcaag
     5101 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaaa caggaaagtg
     5161 gattttaatc aaaattggta ctttaaactc aatgcaaatt ctaaggaagc cattaaacct
     5221 gatgcagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
     5281 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
     5341 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
     5401 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
     5461 ccaaatggtt ataaccagtt ctcatacgat atcaccaaat acctttacaa agatggtcgt
     5521 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     5581 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     5641 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     5701 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     5761 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     5821 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     5881 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     5941 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     6001 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     6061 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     6121 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     6181 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     6241 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     6301 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     6361 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     6421 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     6481 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     6541 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     6601 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcatcagc aacccgtaca
     6661 cgaggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     6721 tatgaacagt cagattatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     6781 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     6841 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcccgttaa gagctcttac
     6901 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     6961 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     7021 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     7081 aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc ttggtcttaa gactttcaat
     7141 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     7201 cttgaatgga aagttgccta tcaaccaggt accttggaag caattgctcg tgatgaatct
     7261 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     7321 attaaggaag atcatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     7381 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     7441 catggtcaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     7501 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     7561 gtcaaatcaa ctgaacaagc agggaaattc acccttactg cccactctga tctcttgaaa
     7621 tcgaaccaag tcactgtctt tactggtaag aaagaaggac aagagaagac tgttttgggg
     7681 acagaagtgc caaaagtaca gaccattatt ggagaggcac ctgaaatgcc taccactgtt
     7741 ccgtttgtat acagtgatgg tagccgtgca gaacgtcctg taacctggtc tcaagtcgat
     7801 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     7861 catgtcaagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     7921 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     7981 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     8041 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     8101 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaagca
     8161 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     8221 ttgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     8281 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggccc tcttcaaacc
     8341 tatgcaattc aattccttga agaagcgcca aaaattgctc acttgagctt gcaagtggaa
     8401 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     8461 gatggaacgc aagctgtatt accagctgat aaagtaacct tctctacaag tggtgaaggg
     8521 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctgaac
     8581 gctgaatatg agggagctaa agaccaagtt gaactcacta tccaagccaa tactgagaag
     8641 aagattgcgc aatccatccg tcctgtaaat gtagtgacag atttgcatca ggaaccaagt
     8701 cttccagcaa cagtaacagt tgagtatgac aaaggtttcc ctaaaactca taaagtcact
     8761 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     8821 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     8881 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagtgttcgg
     8941 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtcca
     9001 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaagg tacgcaatta
     9061 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     9121 caatggaccg gttcagaatt gccacttgcc tttgcttcag actcaaatcc aagcgaccca
     9181 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     9241 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     9301 ttgagcaaac gctccgttga taatctaagt gtcggattcc atgaagacca tggagttggt
     9361 gtaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     9421 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     9481 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     9541 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     9601 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa gcaaggacaa
     9661 acaagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     9721 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     9781 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     9841 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gagcttactt
     9901 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     9961 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
    10021 ctgacagttg aatgggaaga agttccagcg gaaaatctga caaaagcagg tcaatttact
    10081 gttcgaggcc gtgtccttgg tagtaacctt gttgctgagg tcactgtacg agtgacagac
    10141 aaacttggtg agactctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
    10201 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
    10261 ggagatcatt cagaaaatcg tcgttggaca aactggtcac caacaccatc ttctaatcca
    10321 gaagtatcag cgggtgtgat tttccgtgaa aatggtaaga ttgtagaacg gactgttgca
    10381 caaggaaaag ttcagttctt tgcagatagt ggtacggatg caccatctaa actcgtttta
    10441 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
    10501 gacgcagacc atccattcaa caatccagaa aattgggaag ctgttcctta tcgtgcggat
    10561 aaagacattg cagctggtga tgaaatcaac gtaacattta aagctatcaa agccaaagct
    10621 atgagatggc gtatggagcg taaagcagat aagagcggtg ttgcgatgat tgagatgacc
    10681 ttccttgcac caagtgaatt gcctcaagaa agcactcaat caaagattct tgtagatgga
    10741 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
    10801 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
    10861 gaagatagct ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
    10921 taccgtatcc acttgactaa ggaaaaacca gtttctgaga agacagttgc tgctgtacaa
    10981 gaagatcttc caaaaatcga atttgttgaa aaagatttgg catacaagac agttgagaaa
    11041 aaagattcaa cactgtatct aggtgaaact cgtgtagaac aagaaggaaa agttggaaaa
    11101 gaacgtatct ttacagcgat taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg
    11161 gtagaagttc cgacagaccg catcgtcttg gttggaacca aaccagtagc tcaagaagct
    11221 aaaaaaccac aagtgtcaga aaaagcagat acaaaaccaa ttgattcaag tgaagctagt
    11281 caaactaata aagcccagtt accaagtaca ggtagtgcgg caagccaagc agcagtagca
    11341 gcaggtttaa ctcttctagg tttgagtgca ggattagtag ttactaaagg taaaaaagaa
    11401 gactagaaat tttgatacct tctttatcat taaagaccaa agaaaaactc ttgtcctaaa
    11461 tagaagataa agagcctgag acaaaatagt tctcaaccac aaaaaagcta gatatttcca
    11521 attgtggaac tctagctttt taattttgag tcattctctt attgtatagt agattgaaac
    11581 tagaatagta cacttttact tctaaaacat tgttagaaat cgatttgatt gtccttatcg
    11641 atttgtcctg ttcttatttc attttactat attttaggag gttattggcc ataagtacca
    11701 atcccatgtc aattctcact tgacgcttcc ctctcagatt acatctcttg taacccaaag
    11761 aagcctttat ctgcccaaag acaggttcca catcaatctt gcgttgagcg aaaatctgtc
    11821 taccttgggg agataaaagc gcctgacatt ctttagcttt caagttttga tagcgttcgt
    11881 tcatatacag tcccttttga ggggctgatt caggttcgtc ggcgtagtaa accttgattt
    11941 cttgttgaaa gtctgtctgt gttttctgat atttggtatg gtgaaaacga taataccagc
    12001 catcaggatg tgtgtagcta tcctccttgt cattatagtg ccaattcgct aagtttttag
    12061 ctgactcttt ataccctctc ttttgtttct tatcaaacat ggcatattta atcagaaggg
    12121 gagtgatttc ttcttgaaaa tagacctgta tctgttcttg aagtttggcg gagaatttct
    12181 ctgtcgtttt cttccacaca aaactatact tgttggcatt ggcttcaatc ttagttctgt
    12241 caataaacaa acaatctaag gtcactaact cttccatttt tcaatttttc gaccagagaa
    12301 aatcccttgt gaataggcaa atagaagagt agatacaagc attttagggt gataagacgg
    12361 gcgatcaaag gcatgatagg aggtgtagaa gtgacgttcc tccaaggtat tcaccacttt
    12421 ttcaatagta aaaacgagat gatcttgtgg taagaaggaa ctgatttcta gtggtaaagt
    12481 tgtttgattt gtgttatagt gaatatgcat gggatagcct ttctaaatgg tttattgggc
    12541 aattctattt taccaagact atcgtaacca tgcaaaaaag caacggcaaa tccgttgcct
    12601 ttttggatat aagagactat tgtcccagac tcttttcttt gtataaaatt gtatagtgtt
    12661 attgtctata ctattttgta gagaaagcaa aaatccctag aaaatgctta gggattcgac
    12721 tatttcatta agaacaattc aacaatcatt tctatataca tgataagggt taataagaat
    12781 cctgcacgcc agaagaattt gataaattta ggatagtaaa agctgcgttt tttcaaaagg
    12841 aagaaaaaga cgagaataat ggctaggatc gagagggcta gccccagtct agggaggaaa
    12901 ttatgggtaa aggttttagc tgtaatcaag taatactcaa ataccaagac tggaaaagcc
    12961 aaatccgcaa agtttcgtcc tagttttttt aatctaaaaa gtttggttag gataatgcag
    13021 acgactaagg tcagtatcaa taataaaata gatgctaatt tcattaaaat catacccata
    13081 ttgtatcata aaaaaaggct aatggaaacg agaaacagag gaatttatag gaaagtcagg
    13141 cttttgagat tgtgggtgat ttttgttata atgaaagtca tgaaatctta taataccttg
    13201 aatgattatt atcgaaaact ctttggagaa aagactttta aagtccctat tgatgcggga
    13261 tttgactgtc ccaatcgtga tggaactgtg gctcatggag gctgtacttt ttgtacggtt
    13321 tcaggttctg gagatgctat tgtagcccca gatgcgccta tccgtgagca attttataag
    13381 gaaattgact ttatgcaccg taagtggccg gatgttcaga agtatctggt ttattttcaa
    13441 aattttacca acacccatga aaaggtggaa gttgttcgag agcgttatga acaggctatc
    13501 aatgagccag gtgtggtagg tatcaatatt ggaacgcgcc cagactgttt accagacgaa
    13561 accatcgaat atttggctga gttatcggag tgcatgcatg tgacggttga attgggcttg
    13621 caaactactt atgaagcaac ctctgacctg attaaccgtg cgcattctta tgaattgtag
    13681 gtggaaacgg tcaagcgttt gagaaagtat ccaaaaattg agattgtttc ccatttgatc
    13741 aatggtttgc ctggtgaaac ccatgagatg atggttgaaa atgtccgccg ttgtgtcacg
    13801 aataacgata ttcaagggat taaactgcat ttgctccatc ttatgacaaa tactcgtatg
    13861 caacgagatt accatgaggg acgtttacaa ttgatgagtc aggacgaata tgtcagggtc
    13921 atctgtgacc aactggaaat cattcccaaa catatcgtca tccatcgaat tacaggagat
    13981 gcgcctaggg atatgctgct tgggcttatg tggagcctca ataaatggga agctctcaac
    14041 agcattgaga tggagatgcg acgtcgtgga agtgttcaag gatgcaaggc tgtaaaacag
    14101 gagtttgaaa atgaaaagac cacttgagat ggcacatgat tttttggctg aggtcgtgac
    14161 aaaagaggat gtcgtagtgg atgcgactat gggaaatggt catgacacgc tttttttagc
    14221 caagctagcc aagcaagtct atgcctttga tattcagaag caagccttgg aaaagaccca
    14281 agagcgtttg catcaggctg gcttgacaaa tgcccagtta atcttgcaag gccatgagac
    14341 actggaccag tttgtgacaa aagctaaggc agggattttt aatttgggct atttgccgtc
    14401 agctgataag tctgtcatca cccgaccgca gacaacgatt gaggcattag aaaagctatg
    14461 tggcttactt gtcaaaggtg gacgaattgc tattatgatt tactatggtc atgaaggagg
    14521 cgacctcgag agagatgctg tcttggattt tgtgatccag ttgaaccaac aagagtacac
    14581 agctgccatt taccgaactt taaaccaagt caacaacccg ccgtttttag tgatgattga
    14641 aaaattagag agatacagac atggataaac aatacctaca cgaaaagctg gatgccatgc
    14701 gccagaattt tgttgaatca acccaccacg aacgagcggt gggcgtgcta gaccaagcgc
    14761 atatgagcaa aaaaatgctt aaaatcaaga aaaaattagt tgctcttgaa atggaacggt
    14821 gccagagaaa aattgagcac aaagactgtt ccaagattga ccaaaaaatc aaagagcaga
    14881 aggagatatt tgaatcctgt tgtaaaaaag attaaggagg acgtgcgtgg aattactgat
    14941 ttacctcatc ctatttttac tggttttgat tgtctcaagt acaaccaata agctcctgcc
    15001 ctttttgcct ctccctttgg tgcagattct tttgggaatt gtgattggtc tctttttacc
    15061 caatactgac tttcacctta atacggagtt gtttttggca ctggttatcg gacccttgct
    15121 tttccgagag gctgaagaag cagatgttac ggctatttta aaacactggc gaatcattgt
    15181 ttatctcata tttccagtga tttttatctc gaccctgagt ttgggtggct tggcccatct
    15241 tctttggttc agccttccct tggcagcttg cttggctgtt ggtgcagccc ttggtcctac
    15301 ggacttggtg gcctttgcct ctctttcgga gcgttttagc tttcctaagc gcgtgtccaa
    15361 tattcttaag ggcgaaggac tcttgaatga tgcttctggt ttggtggctt ttcaggtagc
    15421 tttgacagct tggacaactg gagctttttc tctggggcaa gctagcagtt cgctcatctt
    15481 ttcaatccta ggcggttttt taattggatt tttaacagcc atgaccaacc gcttcctcca
    15541 taccttcttg ctaagtgtgc gcgcaacgga tattgccagt gaacttttat tagaattgag
    15601 tttgcctcta gtgaccttct ttctggcaga agaagtccat gtttcaggga ttattgccgt
    15661 cgtagttgct ggaattttaa aggcaagtcg cttcaagaaa atcacgctcc tcgaagccca
    15721 agtggatacg gtgaccgaga cggtctggca tacagtgacc tttatgctca acggttctgt
    15781 ctttgtgatt ttagggatgg agttggaaat gatagcagaa cctatcttga ccaatccaat
    15841 ctataatcct ctacttttat tgctatctct catcgccctt acctttgtcc tctttgtcat
    15901 tcgttttatt atgatctatg gctattatgc ctatagaacc cgacgcctca agaaaaagct
    15961 aaataagtat atgaaggaca tgtttctctt gaccttttca ggtgttaagg gaacggtgtc
    16021 gattgctacg attctcttga taccaagtaa tctagaacag gagtatcctc tcttgctttt
    16081 ccttgttgca ggtgtgacgc ttgtcagctt tttaacaggt ctcttggtct tgcctcatct
    16141 ttctgatgaa gaggaagaaa gcaaggatta tctcatgcat atcgccattt tgaatgaagt
    16201 aacgctagag ttggaaaaag agttggaaga caccagaaat aaacttcccc tctatgcggc
    16261 tattgacaat tatcatggac gtattgaaaa tctcatttta agccaagaaa accaggatga
    16321 tcaagaagat tgggctgctt tgaaactctt gattcttagt attgaaagtg atggtttgga
    16381 gcaggcctat gaagagggga acattagcaa tcgtgcttac cgagtttacc aacgttatct
    16441 gaaaaatata gaacaaggaa tcaatcgtaa acttgcctca agactgacct attatttcct
    16501 tgtttctttg cggattttac gttttctcct tcatgaagtt tttactctcg gaaagacctt
    16561 ccgtagctgg aagaacaagg agcaaagccg tctccgtgct cttgattatg accaaattgc
    16621 agagctctat cttgccaata cagagatgat tattgaaagt ttggaaaacc tgaagggagt
    16681 ctacagacgc tctttgatta gttttatgca ggagtctcgt cttcgagaaa cagctattat
    16741 cagcagtggt gcctttgtcg aacgggttat caatcgtgtc aaacccaaca atatcgatga
    16801 aatgctgaga ggctattatc tggagcgcaa gttgattttc gaatacgaag aaaaacgatt
    16861 gattacgact aagtatgcca agaaattacg acaaaatgta aataacttag agaactattc
    16921 cttgaaggaa gctgccaata ccctaccgta tgatatggtg gaattggtaa gaagaaatta
    16981 gttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg tatgtatgtg
    17041 actgacttcg tcagtcttat ctacaacctc aaaacagtgt tttgagcagc ttgcggctag
    17101 ctttctagtt tgctctttga ttttcattga gtataagatt ataaatgaag gagtatgaca
    17161 tgaaaaagtg gtggaaagag ctgatagaca aacctttatt aaaagctttt ttgcattatt
    17221 atcaagcatc agatagtgag ttgaccagtg tcgcagtagc ctactattgg ttgatttcga
    17281 ttttccccct gcttttggtg gtggtcaata tcctccccta ttttcagatt cctgtgggag
    17341 aatttttggg ctttatgaaa gacgtcctgc ccccaagcct ctatgaaggt gtggaaaaaa
    17401 tagccagaga agtcttgacg caaccttcaa caggtttatt gagtttttct gttttatcgg
    17461 cgttatggag tttttcaaaa tctatgaatt tcttgcaaaa agcttttaac aaggcttatg
    17521 gcgtcgaaaa gagtcgtgga cttatttccc atcagatgct aagtctccta gtcagttttg
    17581 gcttgcagct cctctttgcg tttgccttgt ttttgatctt atttggtcag atgattttgg
    17641 ctttacttgc tcattattgg acaaaagatg gcattatcta tcaggcttta caagggttgg
    17701 caggtcctct gatttacgcc ctcctctttg ctatcttggt catgctttat tattttcttc
    17761 ccaatctatc taacaggaaa attagctata ccctaccagg cagtgccttt gttctcttag
    17821 tgattttagg tttactaact ctgttctcta gttatctcaa ttactatgtc catcatttgg
    17881 tggatgtccg aattttaggt tccgttcttc ttgttgttat gatgttttgg tttatcttga
    17941 ttgctaaaat tgttatccta ggcgcggtga tcaatgccag tatgcagagt ttgaaagatc
    18001 cggtctttaa aaaagactaa ctatttatcc attacaaaag cgcatagtat caagattcta
    18061 taaagccttg atactatgcg cttttgtgct ttgacagttt tttgtatagt ttttgtccaa
    18121 gatttctaaa tcatctgatt aaattcctat tttcccctat cattgtccct gttttttcga
    18181 aaatggaagg agtataataa atctatcaat aaaatgatag gaggaacttt atgggtcata
    18241 ttttcttttt tctaagtgtc tttttggcag ggattctatc cttcttttct ccttgtatct
    18301 tacctttgtt accggtctat acaggagtgt tactagatga taaggatggt gctcaggctt
    18361 ctagcggcaa attttcaatc tcagttacta gtttattacg aactctggcc tttatagcag
    18421 gaatttcctt tatatttatt ttgttgggct atggagctgg ttttttaggc gatttgcttt
    18481 atgcttcttg gttccaatat cttactgggg caattattat ccttcttggt ttgcaccaaa
    18541 tggagattct acactttaag gggctttata aggaaaagag gctacaactg caaggacagg
    18601 ggcaaaatgg taagggctat agtcaggcat ttttattggg cttgaccttt agttttgctt
    18661 ggacgccttg cgtggggccg gttctggggt ctgttttggc cttggcggct tcaggtggtt
    18721 caggagcttg gcagggagct ggtctcatgt tggtgtatac gctgggcttg gcgctaccat
    18781 tcttgcttct agctctgacc tctagttatg ttttgaaaca tttccgaaaa cttcatccct
    18841 atctcggaat cctcaaaaaa gtgggtggtt ttctcattat tgtgatggga ttcttggttc
    18901 tgtttggaaa tgcttcaatt ttaagtcaat tatttgaata aaatggaaag gaatatcaat
    18961 atgaaaaaat ggcaaacatg tgttcttgga gcaggttcgc tcctttgttt gacggcttgt
    19021 tcaggcaagt ccgtgactag tgaacaccaa acgaaagatg aaatgaagac ggagcagaca
    19081 gctagtaaaa caagcgcagc taaagggaaa gaggtggctg attttgaatt gatgggagta
    19141 gatggcaaga cctaccgttt atctgattac aagggcaaga aagtctatct caaattctgg
    19201 gcttcttggt gttctatctg tctggctagt cttccagata cggatgaaat tgctaaagaa
    19261 gctggtgatg actatgtggt cttgacagta gtgtcaccag gacataaggg agagcaatct
    19321 gaagcggact ttaagaattg gtataaggga ttggattata aaaatctccc agttctagtt
    19381 gacccatcag gcaaactttt ggaaacttat ggtgtccgtt cttacccaac ccaagccttt
    19441 atagacaaag aaggcaagct ggtcaaaaca catccaggat tcatggaaaa agatgcaatt
    19501 ttgcaaactt tgaaggaatt agcctaggag gcgtcttatg aatgataagt taaaaatctt
    19561 cttgttgcta ggagtatttt ttctagccat aaccggtttc tatgttctat tgatacgaaa
    19621 tgcagggcag acagatgcct cgcaaattga aaaggcggca gttagccaag gaggaaaagc
    19681 agtgaaaaaa acagaaatta gtaaagacgc agacttgcac gaaatttatc tagctggagg
    19741 ttgtttctgg ggagtggagg aatatttctc acgcgttccc ggggtgacgg atgccgtttc
    19801 aggctatgca aatggtagag gagaaacaac caagtacgaa ttgattaacc aaacaggtca
    19861 tgcagaaacc gtccatgtca cctatgatgc caagcaaatt tctctcaagg aaatcctgct
    19921 tcactatttc cgcattatca atccaaccag caaaaataaa caaggaaatg atgtggggac
    19981 ccagtaccgt actggtgttt attacacaga tgacaaggat ttggaagtga ttaaccaagt
    20041 ctttgatgag gtggctaaga aatacgatca acctctagca gttgaaaagg aaaacttgaa
    20101 gaattttgtg gtggctgagg attaccatca agactatctc aagaaaaatc caaatggcta
    20161 ctgccatatc aatgttaatc aggcggccta tcctgtcatt gatgccagca aatatccaaa
    20221 accaagtgat gaggaattga aaaagaccct gtcacctgag gagtatgcag ttacccagga
    20281 aaatcaaaca gaacgagctt tctcaaaccg ttactgggat aaatttgaat ccggtatcta
    20341 tgtggatata gcaactggag aacctctctt ttcatcaaag gacaagtttg agtctggttg
    20401 tggctggcct agttttaccc aacccatcag tccagatgtt gtcacctaca aggaagataa
    20461 gtcctacaat atgacgcgta tggaagtgcg gagccgagta ggagattctc accttggcca
    20521 tgtctttacg gatggtccac aggacaaggg cggcttacgt tactgtatca atagcctctc
    20581 tatccgcttt attcccaaag accaaatgga agaaaaaggc tacgcttatt tactagatta
    20641 tgttgattaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    20701 agggttactg acttcgtcag ttttatctac agcctcaaag ctatactttg agctgacttc
    20761 gtcagtttta tctacagcct caaagctata ctttgagctg acttcgtcag ttttatctac
    20821 aacctcaaag ctatactttg agctgacttc gtcagtttta tctacaacct caaagcggta
    20881 ctttgagaaa cctgtggcta tcttcctagt ttactttttg atttttattg agtataagag
    20941 gtctttccta agcagttaga ggagaatttt gctatactga tactagtaag tggtaaagga
    21001 gcagatcatg acctacacaa tcttaatcgt agaagatgaa tatctggtaa gacaaggttt
    21061 gactaaactg gtcaatgtag cagcctacga tatggaaatc atcggtcagg ctgaaaatgg
    21121 aaggcaggct tgggaattga tccaaaagca ggtgccagat atcattttaa ccgatatcaa
    21181 catgcctcat ctaaatggca tccagttggc cagtctggta cgagaaacct atcctcaggt
    21241 tcatttggtc tttttaacag gttacgatga ttttgattat gccttgtctg ctgtcaaact
    21301 aggtgtggac gactacctgc tcaaaccctt ttctcgtcag gatattgagg aaatgttggg
    21361 gaaaatcaaa caaaaactag acaaggaaga gaaagaagag cagttacaag atttattgac
    21421 taataggttt gaaggaaaca tggcccagaa aatccagtct catctggctg atagccaatt
    21481 tagtttaaag tctttagcca gtgacttagg ttttagtccg acctatctga gttccttgat
    21541 taagaaagag ttgggcttgc cttttcagga ttatctggtg agagaacgtg ttaaacaagc
    21601 caagctcttg cttttaacta cagatctgaa gatttatgag atcgcagaga aggttggttt
    21661 tgaagatatg aactatttta cccaacgttt taagcagatt gcaggtgtga cacctcgtca
    21721 gtttaagaag ggagaagacc gatgaagcgt tcttctcttt tagttagaat ggttatttcc
    21781 atctttctgg tctttctcat tctcctagct ctggttggaa ctttctacta tcaatcaagt
    21841 tcttcagcca ttgaggccac cattgagggc aacagccaaa cgaccatcag ccagactagc
    21901 cactttattc agtcttatat caaaaaacta gaaaccacct cgactggttt gacccagcag
    21961 acggatgttc tggcctatgc tgagaatccc agtcaagaca aggtcgaggg aatccgagat
    22021 ttgtttttga ccatcttgaa gtcagataag gacttgaaaa ctgttgtgct ggtgaccaaa
    22081 tctggtcagg tcatttctac agatgacagt gtgcagatga aaacttcctc tgatatgatg
    22141 gctgaggatt ggtaccaaaa ggctattcat cagggagcta tgcctgtttt gactccagct
    22201 cgtaaatcag atagtcagtg ggtcatttct gtcactcaag aacttgttga tgcaaaggga
    22261 gccaatcttg gtgtgcttcg tttggatatt tcttatgaaa ctctggaagc ctatctcaat
    22321 caactccagt tggggcagca gggctttgcc ttcattatca atgaaaacca tgaatttgtc
    22381 taccatcctc aacacacagt ttatagttcg tctagcaaaa tggaggctat gaaaccctac
    22441 atcgagacag gtcagggtta tactcctggt cacaaatcct acgtcagtca agagaagatt
    22501 gcaggaactg attggacggt acttggcgtg tcatcattgg aaaagttaga ccaggttcgg
    22561 agtcagctct tgtggacctt gcttggggcc agtgtcacat ctcttcttgt ctgtctctgc
    22621 ttagtgtggt tcagtcttaa acgctggatt gctcctttga aggatttgag agaaaccatg
    22681 ttggaaattg cttctggtgc tcaaaatctt cgtgccaagg aagttggtgc ctatgaactg
    22741 agagaagtaa ctcgccaatt taatgccatg ttggatcaga ttgatcagtt gatggtagct
    22801 attcgtagcc aggaagaaac gacccgtcag taccaacttc aagccctttc gagccagatt
    22861 aatccacatt tcctctataa cactttggac accatcatct ggatggctga atttcatgat
    22921 agtcagcgag tggtgcaggt gaccaagtcc ttggcaacct atttccgctt ggcgctcaat
    22981 caaggcaagg acttgatttg tctctctgac gaaatcaatc atgtccgcca gtatctcttt
    23041 atccagaaac aacgctatgg agataagctg gaatacgaaa ttaatgaaaa tgttgccttt
    23101 gataatttag tcttacccaa gctggtccta caaccccttg tagaaaatgc tctttaccat
    23161 ggcattaagg aaaaggaagg tcagggccat attaaacttt ctgtccagaa acaggattcg
    23221 ggattggtca tccgtattga ggatgatggc gttggcttcc aagatgctgg tgatagtagt
    23281 caaagtcaac tcaaacgtgg gggagttggt cttcaaaatg tcgatcaacg gctcaaactt
    23341 cattttggag ccaattacca gatgaagatt gattctagac cccaaaaagg gacgaaagtt
    23401 gaaatatata taaatagaat agaaactagc taactcccag tcaattctgg gagttttatg
    23461 cgtaattggg caaactttat aggttgtcta tcttgctaaa aacaagaaaa aacggtatga
    23521 tagaagagtg acaacagagg taacagagat gaacgagaca cagattcaaa gagaaacacg
    23581 tcaggtagtg gaagatgttt tagaaaagac caatttgaag cagggggtcc tttttgtttt
    23641 aggtctatct tctagtgagg tgctaggtgg tcagattggg aaagaatcca gtcaagagat
    23701 tggtgagctg atagtggaga ctatcttggg tattctaggt agtagaggta tccatttagc
    23761 agttcaaggt tgtgagcatg tcaatcgggc tctcgttgtt gaacgtcagg tggcagagca
    23821 gtttgatctg gaaattgtca gtgtccatcc tactcttcat gcaggaggtt cggggcagtt
    23881 ggcagccttt aagtttatgc aggatccagt tgaggttgaa tttatcaagg ctcatgctgg
    23941 attggatatc ggagacactg caattggcat gcatgtcaag catgttcagg ttccgattcg
    24001 ccctattttg agagagattg gtcatgccca tgtaacggca ctggctagtc gtccaaaatt
    24061 aatcggaggt gcgcgtgcgc actatccgca agacgctatt agaaagtctt gagaatgaat
    24121 aaaggagata aaagtgttta aaaaagaccg tttttcaatt cgtaagatta agggagttgt
    24181 aggctctgta tttcttggaa gccttttgat ggctccttct gtagtggacg cagccaccta
    24241 tcactatgta aataaagaga ttatttcaca agaagctaaa gatttaattc agacaggaaa
    24301 gcctgacagg aatgaagttg tatatggttt ggtgtatcaa aaagatcagt tgcctcaaac
    24361 agggacagaa gcatctgttt tgacagcttt tggtttgctg actgttggga gcttgctttt
    24421 aatctacaag agaaagaaaa ttgctagcgt ctttctagtt ggagctatgg gattggtagt
    24481 tcttcctagt gcagaggctg tagacccagt tgcgacccta gcgctggcta gtcgagaggg
    24541 tgttgttgaa atggatggct atcgctatgt tggttatcta tcaggtgaca tcctcaaaac
    24601 gcttggcttg gacactgttt tagaagaaac ctcagcaaaa cctggagagg tgactgtagt
    24661 cgaagttgag actcctcaat caacaacaaa tcaggagcaa gctaggacag aaaaccaagt
    24721 agtagagaca gaggaagctc caaaagaaga agcacctaaa acagaagaaa gtccaaagga
    24781 agaaccaaaa tcggaggtaa aacctactga cgacaccctt cctaaagtag aagaggggaa
    24841 agaagattca gcagaaccag ctccagttga agaagtaggt ggagaagttg agtcaaaatc
    24901 agaggaaaaa gtagcagtta agccagaaag tcaaccatca gacaaaccag ctgaggaatc
    24961 aaaagttgaa caagcaggtg aaccagtcgc gccaagagaa gacgaaaagg caccagtcga
    25021 gccagaaaag caaccagaag ctcctgaaga agagaaggct gtagaggaaa caccgaaaca
    25081 agaagataca cagccagaag tagtagaaac aaaagatgag gctgctaatc aacctgttga
    25141 agaaccaaaa gttgaaacgc ctgctgtaga aaaacaaacg gaaccaacag aggaaccaaa
    25201 agttgaacaa gtaggtgaac cagtcgagcc aagagaagac gaaaaggcac cagtctctcc
    25261 agaaaagcaa ccagaagctc ctgaagaaga gaagactgcg gaagaaacac cgaaacaaga
    25321 agataaaata aagggtattg gtactaaaga accagttgat aaaagtgagt taaataatca
    25381 aattgataaa gctagttcag tttctcctac tgattattct acagcaagtt acaatgctct
    25441 tggacctgtt ttagaaactg caaaaggtgt ctatgcttca gagcctgtaa aacagcctga
    25501 ggtaaatagc gagacaaaag ctgaaaaagt tgcagctaat acagatgcta aacaaagtga
    25561 agtaaattct gagactgcaa gtcttaaaac agcaatttct ggattaaata cagataaagt
    25621 tgaactcgaa aatcaactta agattgcaca gggaaaaact gaaactgatt tcagcatgga
    25681 atcttggacg gttttgagta cagctaaaaa taaagctcag gaagtaaaag ataacggaac
    25741 agcgacccaa gaacaaataa acgaagcaga gaaaagtttg aaaacagccc ttgctgactt
    25801 atctgttgac aaaacagctt tgggaagcgc tatcgataca gctaccaaga aaaataaaga
    25861 gaactataca aatcaaacat gggcagagtt agaaacagtt cttacagcag caaaatctgt
    25921 aaacactaac gagtctaaac aaagtgaagt taatgaagct gttgaaaaat taactgcaac
    25981 tattgaaaaa ttggttgaat tgtctgaaaa gccacgtttg actctatcta ttgaaaagag
    26041 agacatagat cgaaaagtta cggtcacgta tactttggaa aatccagcaa atactcaaat
    26101 aaaatcaata actgcaactc tgaaaaaagg agaggaagtt gttaaggatt ttgttttaac
    26161 agaagaaaat cttaaaacta atcatttaac tgctttgttt gaaaagctag attactacaa
    26221 agaatacact ctatctacgg atatggtata taacagagga aatgatgatg agacggagag
    26281 tatttcagaa gaactaattc agctgaatct taagaaacta gaattgaaag atatccagac
    26341 agtctctctg atgaaatttg aaaatggtca agaaagtcag gttacacact tgtctgataa
    26401 accgaccgat ttgagtaaat tatacttaaa agttacatca tcaacgtcta aggatgctgt
    26461 gttagccgtt agctctatag aagaagagat tgttgaaaat aaaaaaatct ttaaaattca
    26521 tgcagataca ccagaattag tagttcgtaa gaaagatggc agtctttcta agggatttga
    26581 ctattacatg gagagagtta tccctcatga tggtgatatt tattatgatt ttaaagactt
    26641 gatttcagct atgacatcta atcctacagg tacgtttatt ttagggagag atatttcctc
    26701 gcgtaatgta aaaccggatg gaaatggaaa atcttatatc aaaggtgaat ttaaaggaaa
    26761 actacttggt acaaatgata atgttagaca ctcgatcttt gacttagaat atccattgtt
    26821 tgatactata aaatcaggag tcgtgaaaga tattgatttc aagcatgtca atatggtatt
    26881 cccagatagc aatcaaggag ataacgtagc aacaattgca agagtaatca aagataagac
    26941 aaaaattgag aatgttaatg ttgaaggtta tctcgagggt cgagatcatg tagctggttt
    27001 agttaataat cttgaaggta attccgaaat tgaaaatata tcctttacag gaaagattaa
    27061 gtctaaaggt ggtaattcta ttacagcagg tattgcaggt agaaatatct tatctcgtgt
    27121 taaacgtgcc tatgtaaatg caaatattga agtccttggt tcaacgaatt cgagtatgct
    27181 tgttgcagta aatggtacaa cattgaatgc tagtggaggt tggggagcct ggggaagact
    27241 tactgagtcc gttgctaaag ggacgttaga aattaaacgc agtggacaag ctggtggagt
    27301 tactgcaaca gtctggcctt atggagcaat tgataaggtt gtcagctatg caaaagttac
    27361 caaaggaaaa gaattatttg ggtcagatgg tgatttaaat aataattggt ttatgcaaaa
    27421 aattaataat atttttggtg ttcaaggtat cagctcaggt gactcaggga atgattctaa
    27481 gtttaagcgt atttccgagg aagaagcaaa gcaaaaggtt gcctcttata atattacagc
    27541 tcccaacttg atgagcgact caagtctttt ggtagacaga ctcaatgaaa gttggaaaaa
    27601 tactgatcaa tttgaaagta tacaggatta tcaatcccaa aaccaattaa tttaccagaa
    27661 cttgactaaa tttactcctt attacaataa agaatttatt gttcatgaag gaaatgctct
    27721 cactcctgaa caggaaatat tgaagactaa gaaaatcaaa tcgattgtag ggttgaaagg
    27781 aacagagttc gttgtagatg gcagtgatat tgatactatc atgcttcatt ttgaggatgg
    27841 tagtcagaag cgatataagg taacctctac tggtaagttt tcgataacta atttaccgga
    27901 atatcaggtt gaagatttaa atgtggtgta tacatcagaa catatagtac atccactaga
    27961 ttcgtcactg ataaataacc ttgttgaaga attgaaaaaa gtagaattgt atacagagtc
    28021 tacttaccaa gttctaggta ttgataaaga taatgctaac aaattgaata gaactaagag
    28081 attattctta gatgagtcat tagatgctgt taaaacacaa ttgcctacct ttgtaaaaac
    28141 aatgtttgaa aatgagtggt tgcacatcaa tggagaatct agtggagctg tcgctgcttt
    28201 acgacaaaaa atcatggata ataagacggc tatattgctt gctttgactt atatcaatcg
    28261 ttattatgat gttaaattct cagactataa tattaaaaaa ctgatgctct ttaaaccaac
    28321 tttccatggt gaaaagattg atctattaga tcgattaatc cgactaggat catctggaga
    28381 aaatagatta aaaggttcag aaaatgcaga aacgttcaag cagttatttg ctagcgaaac
    28441 gaagcagaag gatttggtga cttatttaga ctacaatcgc tctttgttga ctaattatca
    28501 aacaacaggg gaatggttta aagaaacgac taaggattat attcaatttg aggaacgtcc
    28561 atccttagta gaggagatta aagatgccaa atatcgagtt tacgataatt taaccgcacc
    28621 gtattatcaa ggatatatcc tacctctctt aacgttgaag aatactcatt tagcaatttt
    28681 atcgaactat agtactatga catttgtcag ccgtgaaaaa cgccctaatt ggaaaaatga
    28741 agattttgat aagtgggtga aatatgtagc aactgctcat agaaaccatg ttgatacttg
    28801 gtataagatt ttacctgata atatcaaagg taaaatggtt aaagagaatg ttactgctgt
    28861 ttgggaagga ttgagcatcc caggaagtga atgggtagac cagaatgctg tagatagaaa
    28921 aggaagagat tacgccccag ctcgagaatt ctttaatctt gtaggtggtc ctatgggagg
    28981 ttggtatgct taccatggtt atggtgcgca tgctggagga agaaatcggg ttaattatga
    29041 ggtgtttgat gtattaagtg agtatggtat atcggtcttt actcatgaat tgactcacgt
    29101 taatgatact tggatttact taggagggta tggtagacgt gaaaatatgg gacctgaagc
    29161 ttatgctcag ggattattcc agtctcctgt tccaggtcag ccgggttggg gggcgcttgg
    29221 tctcaatatg gcatttgaaa gaaaaaatga tggtgatcta atttataatg cctccccaac
    29281 tcaatttgaa aataggaaag agttagatag ttatatgaaa aattataacg atactctcat
    29341 gatggtggac tacttggaag gagatgcagt tatctctaaa ggtaaagaag ctattactaa
    29401 atggtttaaa aaagttgaac ctaaggttgt tagtcaaaca gctcagtatg atacggttcg
    29461 tcagttgact gctgaagaga aagaaaaact ttctgtttct agtgttgatg atttagttga
    29521 tcaaggatta atgtcagaca gagctgtagg aaataatacc tataatccag ctgattttga
    29581 aacaagttat attgcgatag attatatgac tggtatttat ggtggaggaa agaatagtgt
    29641 aggttcacca ggtgccttga tgtttaaaca taatactttc cgtatgtggg gctactatgg
    29701 ttttgaagaa ggtgttctag gatatgcttc taataaattt aagcaagcat ctagagatga
    29761 aggtcatgct ggacttagtg ataactttat tatttctaag atttccaaag gggaattttt
    29821 aactatggaa gcatttaaaa agggatattt taagaaagta gtagaagagt taaaaactaa
    29881 aggtattcgt cctgttacta tcaatcaaaa aacatatagc acctttgaag aattgcaaga
    29941 aggatttaag caggctgttg aaagagattt gaagaaaaat cagttagatg agagggaaac
    30001 aagaaacttc aaattccaag ttttcagaca acttcttcaa caaacagata gctttaaaac
    30061 ttctatcttt agataatcga aatctctcat ctgctttgcg gatgagggtt ttcttatttt
    30121 atgctatact taaggtatgc atagaaaaac agtgattgat tttaggactt taggggagag
    30181 atataccttt acccagccta ttaaagagtt gaaaacgaga aatgtagaag aagtggcaga
    30241 tttgctggca caagtggaaa gctaccaaga gcaaggttat tatgtggtgg ggtatgtcag
    30301 ctacgaggct gcacctgctt ttgaggaaaa attagcagtt cacaaggatc ccctactggg
    30361 agagtacctg ctttatttta ctgttcatga tagcgtagaa acttccccta ttcctctgac
    30421 ttatgaggat attgatttgc cctcaaattg gcaggaagta acgtctgcag cagactatga
    30481 aaaggccatt gcccagatac accatcactt gaggcaggga gacacctatc aggtcaacta
    30541 caccgtccaa ctcaagcaaa agttaagtgc caatcctttt gccatctaca atcgtatggt
    30601 ggtagagcag gaggcgggct acaatgccta tgtggaacat gacgagatgg cagtgatttc
    30661 catgagccca gagctctttt ttgagcaaaa tgatcgcgag ttgacaacac gaccaatgaa
    30721 ggggacgact cagcgtgggg taactgacca agaagatctt gaacaggcca gttggttgga
    30781 acaggatccc aaaaatcgct ctgaaaatat gatgattgtg gacctcttgc gcaatgatat
    30841 gaaccgtatt tctgaagttg ggagcgagca cgtggagcgt ctgtgccagg tagagcagta
    30901 ttcaactgtt tggcagatga cttcgaccat caagagtcag ttgcgagagg atgtggacct
    30961 tgttgaaatc ttccgctcac tctttccttg tggttccata acgggtgcac cgaaaattgc
    31021 gacaatggag attatcaaga acttggagcc tcaaccgcgt ggagtctact gtggaacgat
    31081 tggtctcttg cttccaaatg gacgacggat ttttaatgtg gccattcgta ccattcaact
    31141 tcacaaaggt caagccattt atggagttgg cggagggatt acttgggata gcacatggga
    31201 atctgaatac cgagaggttc atcaaaaggc agcagttctt tatcgtaaac aagctcgctt
    31261 ccaactgatt acgacagggg aaatcagcca gaagaacctg ctgtttgaag atcaacatct
    31321 ggaaagactg agaaaagcta gtcgttattt tgcctttcct tttgatgcag aagacttggg
    31381 acacaagatt gaggaagagt gtcaggattg tgaagctaat caagattacc gcttgcgaat
    31441 cagccttagc aaatctggag agatagaagt caatcgtcaa gtattaaccc ctctcagtac
    31501 aagcttttgt caggcccaag tctgccttca ggaagctgct ttgaatcaat cctttaccta
    31561 ctttaaaacc actcaccgac cgcatttgag cctaggagaa caagagaaga tttaccacaa
    31621 taagtcagga gaactgcttg aaacctctat aggaaatttg gttctgaaaa tcgctggaaa
    31681 actctacaca ccgcctatcc gacttggaat cttgccagga atttaccgtc agcatttgct
    31741 agaaacagga caggtagaag agaaagtctt gaccttggca gatttaaccc aagcagaagc
    31801 tatttacggc tgtaatgcag tgagaggctt gtatgaacta agccttgagg agaactagat
    31861 gaaattgata tttttgcatg ggttagggca gtcagcagag tcttggaaag aagttcggaa
    31921 tctactgaca gattatcctt ctgaggctat cgagttattt ccttctggag ttagtaacta
    31981 tcaacaagct aaagagcgag tttatcagca cctagctcaa gagacagaac cttttgtttt
    32041 gattggattg tccttaggtg ctgccctgac actagaactt tccagttacg atttaccaaa
    32101 tcttcgagct ttgattctgt caggatgccc gcttaaatta gcagggaata tcctatttta
    32161 tcttcagttg ctgattttta aactacttcc caaaagagta tttgaaaaac agggagcaga
    32221 caagactctt atggtcggag tttctgagga attgaagaca cttgatttaa cggatatagc
    32281 agggacttgc tcctatccaa ccttactaat ttgtggcagc aaagataaac cgaatcttag
    32341 ttttatgaaa gctctccata gactgttaac agattcgcag tttcagatca ttcctgatgg
    32401 ccctcatgtc ttgaataagg caaaaccaaa ggagtttgta gaaaagacca gaagtttcct
    32461 tgaattgctg aaataagttt gataaaataa tattgaaatc gatatcataa ttatgggaga
    32521 aagaaatgaa taaacgtcta tttttaaaaa tgagtctggt gacgttgcca attttagcct
    32581 tgttttcaca accagttttg gcggaagaaa acatccattt ttcgagctgt aaggaagctt
    32641 gggcgaatgg ctattcggat attcacgaga gagaacctgg ttattctgcc aagttagacc
    32701 gtgatcatga tggtgtggct tgcgaattga aaaatgctcc taagggtgct tttaaagcaa
    32761 aacagtcaac ggctattcaa atcaacacaa gttcagcaac aacaagtggt tgggttaagc
    32821 aggacggcgc ttggtactac tttgatggaa atggaaatct agtgaaaaat gcatggcagg
    32881 gaagctatta cctgaaagct gatggtaaaa tggcacagag tgaatggatt tatgactctt
    32941 cttatcaagc ttggtattat ttgaaatcag atggttctta tgcaaaaaat gcatggcaag
    33001 gagcttatta ccttaaatca aacggtaaaa tggcacaagg tgagtgggtt tatgattctt
    33061 cttaccaagc atggtattac ttgaaatcag atggttcata tgctcgcaat gcatggcaag
    33121 gaaactacta tttgaaatca gatggtaaaa tggctaaagg tgaatgggtt tatgatgcca
    33181 cctatcaagc ttggtattat ttgacatcag atggttctta tgcttacagt acatggcaag
    33241 gaaattacta tctaaaatcg gatggtaaaa tggctgtcaa tgaatgggtt gatggtggac
    33301 gttattatgt tggcgctgac ggagtttgga aggaaggtca agcaagtaca gtttcttcta
    33361 gtaatgatag caatagtgaa tattctgctg ctttaggaaa ggcaaaaagt tataattcgt
    33421 tattccacat gtcaaaaaaa cgtatgtata gacaattaac ttctgatttt gataaatttt
    33481 caaatgatgc agctcaatat gccattgatc atttagatga ttaacagata ctggtaggcg
    33541 aaaaaattcc ttataattca tttacgcaaa cctttgcata agtgaatgga ttttgatata
    33601 ctagtactgt aagcattttc aattactaca caatgaaaaa ggagaatatg atgagtcaaa
    33661 agattattgg gattgacctt ggtggaactt ctatcaaatt tgcaatctta acaacagcag
    33721 gagaaatcca aggaaaatgg tcaatcaaga ccaacatttt ggatgaggga agtcatatcg
    33781 ttgatgatat gattgagtct attcaacatc gtttggactt gcttggattg gcagcagcgg
    33841 acttccaagg cattggaatg ggatcaccag gtgtggttga ccgtgacaaa gggactgtta
    33901 tcggtgccta caacttgaac tggaaaaccc ttcaaccaat caaacaaaag attgaaaaag
    33961 ctttgggcat tccatttttc atcgataatg atgccaacgt agcagctctt ggtgagcgct
    34021 ggatgggtgc tggagataac caaccagacg ttgtctttat gacactcggt actggtgttg
    34081 gtggtggtat tgtcgcagaa ggcaaattgc ttcatggtgt tgctggtgca gcaggtgaac
    34141 ttggtcatat cactgttgac tttgaccaac caatctcatg tacttgtggt aaaaaaggct
    34201 gccttgagac agttgcttca gcaacaggga ttgtcaactt gactcgtcgc tatgccgatg
    34261 aatacgaagg cgatgcagcc ttgaaacgct tgattgataa cggagaagaa gtaactgcta
    34321 agactgtctt tgatctcgca aaagaaggag acgaccttgc tttgattgtt tatcgtaact
    34381 tctcacgtta cttgggaatc gcttgtgcta acattggttc aatcctaaac ccatcaacaa
    34441 tcgtcatcgg tggtggtgtg tcagctgcgg gagaattcct tctacaaggt gttcaaaaag
    34501 tttacgatga aaatagtttc ccacaagtac gcacatctac taaattagct cttgcaactc
    34561 taggaaatga cgctggagtt atcggagcag catcacttgt attgcaataa gataatgaga
    34621 gaggaaaatg ctaacctaga gttagtaatg ttcctctttt attttttatg ctatactagt
    34681 taggacaatg aatgaggtga gagtaaatga caaaagcaga tacgattttt aaagagaata
    34741 ttgaacgcat tctaaaggaa ggtgttttct cagagcaggc tcgtcctaag tacaaggatg
    34801 ggactgttgc taattccaag tatgtaactg gtgccttttc cgagtacgac ttatctaaag
    34861 gagaatttcc tatcacaacc ttgcgtccca ttgccatcaa atccgccatc aaagaagttc
    34921 tctggattta ccaagaccag tcaaatagct tagaagtgct taatgacaag tacaatgttc
    34981 actactggaa tgactgggaa gttggagaca cgggaaccat tggtgagcgc tatggtgccg
    35041 ttgttaagaa acacgacatt atcaataagc ttctcaaaca gttggaaacc aatccttgga
    35101 accgccgcaa tattatttcg ctctgggatt accaagcttt cgaagaaaca gatgggctgc
    35161 tcccgtgcgc ctttcagacc atgtttgatg tccgccgtat agatggagaa atctatctgg
    35221 atgcgacctt gacccagcgc tcgaatgata tgctggtggc ccaccacatc aacgctatgc
    35281 agtatgtggc tttgcagatg atgattgcca aacattttgg ctggaaggtt gggaagttct
    35341 tctacttcat caacaacctc catatctatg ataatcaatt tgaacaagct caggaattgc
    35401 tccgtcggga gccgtcaaac tgccaaccac gcttggtttt aaatgttcct gatgggacta
    35461 atttctttga tatcaaagca gaagattttg agttggtgga ttatgaccct gttaagccac
    35521 agttgaagtt tgacctagct atttaaaaga atagaaaaaa gaagttgaga ataatcccaa
    35581 cttcttttgt ttcttaacgt gatacgcggc gacgagctgc ttttttacgg ttttcttcga
    35641 tgaaagctgc tttttgctct tctggttcga ttactttctt tttaaatgcg tatactgcac
    35701 ctgcaacggc agcgacagtt cctgcgacac ctgttacaag acctttagcg aatcctttag
    35761 ccatgagtct tcctccttta tattctcaat cagccagcct cctcaagagg tcacattttt
    35821 ctgactgacc tttttgtgtt ataataatag taacgaaaaa atgggaattt ttcaaggaaa
    35881 aaagatgaaa acaaaaataa ttgtgattgt tggaccgact gctgttggaa agacggctct
    35941 agctattgaa gttgcaaagc gttttaatgg cgaagtggtt agtggagata gccagcaagt
    36001 ctatcgagga cttgatattg ggacggccaa ggctagtcca gaagagcagg cagctgttcc
    36061 tcatcattta atcgatgtta gagagataac cgagtcttac tcggcttttg attttgtttc
    36121 agaagctaag atgactattg agggtattca caaccgtggc aagctagcca ttatcgccgg
    36181 tgggactgga ctttatatcc agagcttgct agaaggttac cacctaggtg gggagactcc
    36241 tcatgaggag attttagctt atcgagctag tttggagcca tattcagatg aggaattagc
    36301 ccatttggtg gatcaagcag gccttgagat tccccagttt aatcgtcgtc gtgctatgcg
    36361 tgccttagaa attgcccatt ttggtcagga tttggaaaat caagagacct tgtatgaacc
    36421 gctgattatc tgcttggatg atgaacgtag tcaactttat gagcgtatca accaccgagt
    36481 ggatttgatg tttgaggctg ggcttttgga tgaggccaag tggctgtttg accattcccc
    36541 taatgtacag gctgctaaag gaattggcta taaggaactc tttccttatt tccgtggaga
    36601 gcagaccttg gaggaagcta gtgagagtct caaacaggcg acccgtcgtt ttgccaagcg
    36661 tcagctgacc tggttccgta atcgcatgca ggtcaccttt tatcagattg gagaatctgg
    36721 tgtacaagac cgcattttaa gccagataga ggagttttta gatgattgaa acggagaaaa
    36781 aagaggagcg agtcctgctg attggtgtgg aattgcaggg tatggacagt tttgacctct
    36841 ccatggaaga attggctagt ttagcgaaaa cggcaggggc agtcgttgta gatagctaca
    36901 gacaaaaacg tgaaaaatat gattccaaga ccttcgtcgg ctctggtaag ttggaagaga
    36961 ttgcgcttat ggtggatgca gaagaaatca ctactgtcat cgtcaacaac cgtctgaccc
    37021 caaggcagaa tgtcaatcta gaggaagttc tcggtgttaa ggtcattgac cgtatgcagt
    37081 tgattttgga tatctttgcc atgcgggctc gaagccatga agggaagctc caagtccacc
    37141 tagcccaact caaatacctt ttgcctcgct tggttggtca ggggattatg ctcagccgtc
    37201 aggcaggggg aattggttcc cgtggtcctg gtgaaagcca gctggagctg aaccgtcgta
    37261 gcgttcgcaa tcaaatcacg gatattgagc gccagctcaa ggtggttgag aaaaatcggg
    37321 cgactgtcag agaaaaacgt ttggagtcta gcacttttaa gattggtttg attggttata
    37381 ctaatgctgg gaaatcaact atcatgaaca tcttgaccag taagacccag tatgaagcag
    37441 atgagctctt tgcgactctg gatgcgacaa ccaagagtat tcatctggga ggcaatctcc
    37501 aagtaacttt gacagatacc gttggcttta tccaagattt gccgacagag ttggtgtcca
    37561 gtttcaagtc aaccttggaa gaaagcaagc atgtggacct tctggttcat gttatcgatg
    37621 ctagcaatcc ttaccacgag gagcatgaaa aaacggttct ctccatcatg aaagacctgg
    37681 acatggaaga tattcctcac ttgacgcttt ataataaagc ggatttggtg gaggatttca
    37741 cgcctaccca aacgccatat accctcattt ctgccaagtc tgaggacagt cgtgaaaact
    37801 tgcaagcatt attgctagat aagattaagg aaatttttga agcatttacc ctgcgagtgc
    37861 ctttttcaaa gtcctacaag attcatgatt tagagagtgt tgcaattctg gaagaacgtg
    37921 attatcagga agacggcgaa gtgattacag gctacatttc cgagaaaaat aaatggaggt
    37981 tagaagaatt ttatgactga tattaaaact ttggctctaa agtatggagg ttatacaagt
    38041 ctggacaagg tctatctgga tcagcttcta gctggtaaaa cagagcagga gcagttaaca
    38101 cttattacac ctccgccaag tgttgttaat gcctactttg cagaactcta tcagaaaaaa
    38161 agtcctcagg ctgcgacgga ttattttgca gaactcagtc aggaactgaa tctttacaat
    38221 actgagccaa gtttcaccct agaaaataag ccttttattc ggcttaatct gtctggtaaa
    38281 tcctttggtt tttgttatga gagtgacggc tttggtcgga ttttctctga aaatgaggag
    38341 aaaatctcgg atgacttgct ctttgaaatt gcgcaaattt tctcccatca attagtcttt
    38401 gaagagtctg gtaagattta catgaagcct gtcaaggacg aggaagttgt cagcctagaa
    38461 agtctcacag ctttgactga tttggaaaga ttggctgatg gtcgaaaacg tctcaaaggc
    38521 tacagccaag aggatttatt gcaagaagct gctgcttttt ctggcaaacg ctatttccga
    38581 tcggaaaacc gcacagccat gttatatatt gattaattag aaagtatcga atggatattc
    38641 aatttttagg aacgggggct ggtcagccct ctaaagcccg caacgtttca agtctcgccc
    38701 tgaaactttt ggacgagatt aacgaagttt ggctctttga ctgtggagaa ggtacgcaaa
    38761 atcgcattct ggaaaccaca attcgaccac gtaaggtcag caaaatcttt attactcatc
    38821 tgcatggaga ccacattttt ggtttgccag gtttcctttc tagccgtgcc tttcaggcca
    38881 atgaagagca gacagatttg gaaatctacg gacctcaagg aatcaagtca tttgtcttaa
    38941 ccagccttcg tgtgtcaggt tctcgtctgc cctaccgcat tcatttccat gagtttgacc
    39001 aagattctct gggtaaaatt cttgaaaccg ataaattcac tgtgtatgca gaggagctgg
    39061 accacactat tttctgtgtt ggctatcgtg tcatgcaaaa ggatctagaa gggacgctgg
    39121 atgctgaaaa actcaaggct gctggtgttc cgttcggccc gctttttggt aaaatcaaaa
    39181 acggccagga tcttgttttg gaagacggaa ctgaaatcaa ggcagcagac tatatctcag
    39241 cgccacgtcc aggtaagatt atcactattt taggagacac tcgaaaaacg gatgccagtg
    39301 tgcgtctggc tgtcaatgca gatgtcctag ttcatgagtc cacttatggc aagggtgatg
    39361 aaaaaattgc tcgtaaccat ggtcactcaa ctaatatgca agctgcacaa gtagcggtag
    39421 aagcaggtgc caaacgcctc ctactcaacc atatcagtgc ccgtttcctc tcaaaagata
    39481 taagcaaact caagaaggac gctgccacaa tttttgaaaa tgtccatgtg gtcaaagact
    39541 tggaagaagt ggaaatctag cagtcacaga aaggataagt atgcctacta ttctcattac
    39601 cggagctagc ggtggtctag ctcaagaaat ggtcaaactc ctgcccaatg accaactcat
    39661 cttgcttggt agaaataagg aaaaattagc ccaactctac ggaaattatt cccatgcaga
    39721 attgattgaa attgatatta ccgacgattc agccctagaa gctctggtaa ctgatcttta
    39781 tctccgctat ggcaagattg atgtcttgat taacaacgct ggttacggga tttttgaggg
    39841 atttgaccag attgctgata aagatattca ccagatgttt gaggtcaata cctttgccct
    39901 gatgaatctg tctcgtcacc ttgcggctcg tatgaaggaa agcagcaaag ggcatatcat
    39961 caacatcgtc agcatggcag gtctaatagc tactggcaag tctagtcttt actcagcgac
    40021 caagtttgcg gctattggtt tttcaaatgc tctgcgactc gaacttatgc cctatggagt
    40081 ctatgtgaca acagtcaatc caggaccaat ccgtacagga tttttcgacc aagccgaccc
    40141 agatggaact tatcttaaat cggttgaccg cttcctgcta gaaccagatg cagtggctaa
    40201 aaagattgtc aagattatag gaaaaaacaa acgagaactc aatctcccga ttttgttgaa
    40261 cctagctcat aagttttata ccctctttcc taagctagct gataagttgg caggggaaac
    40321 ttttaattat aagtaaaaag aaccaatgtg caggttgttg ctagcctaca tattggttct
    40381 tatcatttct caactatcaa actgaacttc ttctaggagg tagtctataa agcgttcgcc
    40441 catcttagat aggctggttt tctcatgctg gatatagacc agctcaatcg ggtcatcaat
    40501 atccagtggg atagaaacga tattgtctcc gtttaggttg ctgttcaaaa tccctgtcgc
    40561 aatggtataa ccatccaaac caatcaagag attaaagagg gtggcacggt cactgaccac
    40621 aatggatttc ttgtggtgtt cttgagaaag aatctcttct gaaaagtaga aggagttgtg
    40681 cgtcccttgg tcatagctga ggtaagggaa attctccaaa tcagacagtt tcaccttgtc
    40741 tttctttgcc agagggttgg tcttgctgac aaagatatgt ggttgcgctg tgaagagatg
    40801 gtgggctagc aggtgattgt catccagcat cttggttaaa acatcacggt tgtaactgtt
    40861 taagaagagg accccgacct cactgcggaa gttcttgacg tcgtcgataa tctcccaagt
    40921 ccgagtttca cgaaggaaga gttcgtattt ctccatatcg cttttcttga gcaaagagac
    40981 aaaggcattg accacaaagg catagtgttg agacgaaacg ctaaatagtt cgcggtgggc
    41041 gacaggattt ttatagcgtt cctccagaag ctgggtctgc tcgacaacct gacgggcata
    41101 ggagagaaac tccatcccat cacgggtcaa ggtgattccc ttgggattgc ggataaagat
    41161 ctcaatgccc atttcatttt ccaaatctcg cactgcattg gagagacttg gctgagtgat
    41221 aaagagttgc ttggctgcct cattcatgga gccagtttcg acgattttga taatataatg
    41281 taattgttga attctcatgt ttttattgta ccatacttgc cttagaatcg ctaaagaaga
    41341 tgggaaaata aggagcattg tgtgagtctc ttcttgaaaa aaacacaaaa ttttgctaga
    41401 atgagtctta tgaaaacatt ctatgatgtg cagcaattcc tcaaacgatt tggtattatt
    41461 gtttacatgg gaaaacgctt atatgatatt gaactgatga agttggaact atctcggatt
    41521 tacgatgcag ggttgatgga taaattagac tatctagagg cagaagcagt tcttcgcaga
    41581 gagcacaagg tagaattgga ttatattgag aaaaatggag aaaagaacta atggttactt
    41641 ggattttgtg ggcacttata ctagcaatgt tggcgtggat gggctttaac tatcttcgta
    41701 ttcgccgtgc ggctaaaatt gtggacaatg aggagtttga agccttgatt cgtacgggtc
    41761 aattgattga tttgcgcgac ccagcagaat tccacagaaa acatatcctt ggtgcacgca
    41821 atattccttc aagtcagttg aaaactagtc ttgcagccct tcgtaaagat aaacctgtcc
    41881 ttctctacga aaaccaacgt gcgcaacgag ttacaaatgc agctctttac ttgaaaaaac
    41941 aaggtttttc tgagatttat atcctttctt atggcttgga ttcttggaaa gggaaagtga
    42001 agactagcta accttatttc caaattagtt gaatgatagg atgaagctat tgttttatag
    42061 tataattaat ttgtataaaa tttaaggagt tcttagaaca tgaaagaaaa gaagaaaatc
    42121 cactttttgt gggtatcttg tcgattattc ttggtttgtt atttccaatt gtaggcctga
    42181 ttttgggtat cataggattg gtcttggcta tttcatacca aaaagagtca caattagact
    42241 ataaaataga aaagattctt aatatcttag gaattgtgat ttctgtagtt aactggattg
    42301 tagcaatcgc cttaattttt cggtaaataa aagaaaaaag ctttagtttt aaagcttttt
    42361 ttattttatc gactcatctc taaatagttt ttaatgattt gtaactcttt ttggttcaaa
    42421 gggcggtagt taccttctgc taaatctggg ttcaatgtga agtccccaaa ttggattctc
    42481 ttgaggctag tcaccttaac accaaccgag aggaacattt tcttgatttg atgaaatttt
    42541 ccttctgaaa tggtgataga ggcttgactg atggagggac ttgcagatag aatctctagt
    42601 tttgcgggtt tacagacagt accatctaaa aagacaattc ccttttgaaa ggcttggata
    42661 tggtcaggtg ttagaagtcc attaacctca acttgataag tcttatcgac atgatattgg
    42721 ggatggagga gttggaagcc caagggaccg ttatcggtca agagaaggag tcctgttgta
    42781 tctcggtcca gtcggccgac ggcatagagc ttgtcagact ggatgtcaga tggaagcagg
    42841 tccatgacgg tcggaagttc cttgtctttg ttggctgtaa cgacaccagc aggtttatga
    42901 agcataagat aggtgtgttc atagccttga atgattcgat cctgaaaaag gagttcttgt
    42961 agtcctgtat cgatattttg agctagggag cgggctgggc aaccatcgac tagaatttcc
    43021 cctctgagga gtgcttgttt catggccttt cggctgattt tttcttgagc taataaatta
    43081 tctaaacgca tactgtgcct atcttatcat aagtcgcttg ctttgaaaag gcttgacgtg
    43141 aaaagaaaag cggagtgaaa acatttacac ttgcttgagt tatgttattt atttgaaatt
    43201 atggtataat cgttcagtta gaaaataaat tttgaatatt atagaggaaa tcatgacaaa
    43261 attaagagaa gatatccgta acattgcgat tatcgcccac gttgaccacg gtaaaacaac
    43321 cctcgttgac gaattattga aacaatcaga aacgcttgat gcacgtactg aattggcaga
    43381 gcgtgctatg gactcaaacg atatcgaaaa agagcgtggg attaccatcc ttgctaaaaa
    43441 tactgccgtt gcttacaacg gaactcgtat caacattatg gacacaccag gacacgcgga
    43501 ctttggtgga gaagttgagc gtatcatgaa aatggttgac ggtgttgtct tggtcgtaga
    43561 tgcctatgaa ggaaccatgc cacaaactcg tttcgtattg aaaaaagcct tggaacaaga
    43621 ccttgtccca atcgtggttg ttaacaaaat cgataagcca tcagctcgtc cagtagaagt
    43681 agtggatgaa gtcttggaac ttttcatcga gcttggtgca gatgacgacc agcttgattt
    43741 cccagtggtt tatgcttcag cgatcaacgg aacttcttca ttgtcagatg atccagctga
    43801 ccaagaagcg actatggcac caatctttga cacgattatc gaccatatcc cagctccagt
    43861 agataactca gatgagcctt tgcagttcca agtgtcgctt ttggactaca atgacttcgt
    43921 tggacgtatc ggtatcggtc gtgtcttccg tggtacagtt aaggttgggg accaagttac
    43981 cctttctaaa cttgacggta caactaaaaa cttccgtgtt acaaaactct tcggtttctt
    44041 tggtttggaa cgtcgtgaaa tccaagaagc caaagcgggt gacttgattg ccgtttcagg
    44101 tatggaagac atctttgtcg gtgaaaccat cactccgaca gatgcagtag aagctcttcc
    44161 aatcctacac atcgatgagc caactcttca aatgactttc ttggtcaaca actcaccatt
    44221 tgctggtaaa gaaggtaaat gggtaacctc tcgtaaggtg gaagaacgct tgcaggcaga
    44281 attgcaaaca gacgtttccc ttcgtgttga cccaactgat tcaccagata aatggactgt
    44341 ttcaggacgt ggagaattgc acttgtcaat ccttatcgaa acaatgcgtc gtgagggcta
    44401 tgaacttcaa gtatctcgtc cagaagttat cgtaaaagaa atcgacggtg ttaaatgtga
    44461 accatttgaa cgtgtacaaa tcgacactcc agaagaatac caagggtctg ttatccaaag
    44521 cctttctgaa cgtaaaggtg aaatgttgga tatgatttca actggtaatg gtcaaactcg
    44581 tttggtcttc cttgttccag cgcgtggttt gattggatac tcaactgagt tcttgtcaat
    44641 gactcgtggt tacggtatca tgaaccatac cttcgaccaa tacttgccat tgattccagg
    44701 ggaaattggt ggacgtcacc gtggtgccct tgtttctatc gatgctggta aggctacaac
    44761 ttactcaatc atgtctatcg aagaacgtgg tacgatcttt gtcaacccag gtactgaggt
    44821 ttatgaagga atgatcatcg gtgaaaactc tcgtgaaaat gacttgacag ttaacatcac
    44881 gaaggcaaaa caaatgacca acgttcgttc agctactaag gaccaaacag ctgttatcaa
    44941 gacgcctcgt atcttgacac ttgaagagtc tcttgagttc ttgaacgacg atgagtacat
    45001 ggaagtaacg cctgagtcta tccgtttgcg taaacaaatc cttaacaaag cagagcgtga
    45061 gaaagctaac aagaagaaaa aatcagctga ataagagcta gaaagagaga aagatggtct
    45121 atttagtcct aggaatttta ctgctcctac tctatgtatt tgcgacacca gaaagcatta
    45181 aagggactgt caatatcgtc gctatggtat gtattttagt ggcactcttg attttattgg
    45241 ttctatcttt tctgaaaatt tttcaattac caacagaaat attcctagca atagccatgt
    45301 tgatcctagc ttactttagt gttagagaca tcacactcat gccagtcaaa aaaagtaaaa
    45361 gaagataaaa aagagagttt cggctctctt tttgctagga attttacaat agtttgaatt
    45421 gctttttagt taacaccatc tcttttactt gtatagtatg aatgggaaaa acttgaataa
    45481 aattcgttaa tggcatctat tttatatttg gttagtactg gttgcatatt attttga
//
LOCUS       DAVLHM010000013        45065 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLHM010000013 DAVLHM010000000
VERSION     DAVLHM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.013"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VXE45_000736"
     CDS             complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VXE45_000736"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0788809.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VXE45_000737"
     CDS             complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VXE45_000737"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0788810.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            7816..7886
                     /locus_tag="VXE45_000738"
     tRNA            7816..7886
                     /locus_tag="VXE45_000738"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7848..7850,aa:Cys,seq:gca)
     gene            complement(8084..9415)
                     /locus_tag="VXE45_000739"
     CDS             complement(8084..9415)
                     /locus_tag="VXE45_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0788811.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VXE45_000740"
     CDS             complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VXE45_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0788812.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(10507..10695)
                     /locus_tag="VXE45_000741"
     CDS             complement(10507..10695)
                     /locus_tag="VXE45_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0788813.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VXE45_000742"
     CDS             complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VXE45_000742"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0788814.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(11995..12225)
                     /locus_tag="VXE45_000743"
     CDS             complement(11995..12225)
                     /locus_tag="VXE45_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0788815.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(12283..13320)
                     /locus_tag="VXE45_000744"
     CDS             complement(12283..13320)
                     /locus_tag="VXE45_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0788816.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VXE45_000745"
     CDS             complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VXE45_000745"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0788817.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VXE45_000746"
     CDS             complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VXE45_000746"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0788818.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(14386..15378)
                     /locus_tag="VXE45_000747"
     CDS             complement(14386..15378)
                     /locus_tag="VXE45_000747"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0788819.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(15490..16173)
                     /locus_tag="VXE45_000748"
     CDS             complement(15490..16173)
                     /locus_tag="VXE45_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0788820.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16229..16969)
                     /locus_tag="VXE45_000749"
     CDS             complement(16229..16969)
                     /locus_tag="VXE45_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0788821.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            17003..17281
                     /locus_tag="VXE45_000750"
     CDS             17003..17281
                     /locus_tag="VXE45_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0788822.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17359..18285
                     /gene="yidC"
                     /locus_tag="VXE45_000751"
     CDS             17359..18285
                     /gene="yidC"
                     /locus_tag="VXE45_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0788823.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVHEELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VXE45_000752"
     CDS             complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VXE45_000752"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0788824.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(19280..20530)
                     /locus_tag="VXE45_000753"
     CDS             complement(19280..20530)
                     /locus_tag="VXE45_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0788825.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VXE45_000754"
     CDS             complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VXE45_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0788826.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(21691..22632)
                     /locus_tag="VXE45_000755"
     CDS             complement(21691..22632)
                     /locus_tag="VXE45_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0788827.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(22622..23878)
                     /locus_tag="VXE45_000756"
     CDS             complement(22622..23878)
                     /locus_tag="VXE45_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0788828.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(23880..24542)
                     /locus_tag="VXE45_000757"
     CDS             complement(23880..24542)
                     /locus_tag="VXE45_000757"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0788829.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(24505..25161)
                     /locus_tag="VXE45_000758"
     CDS             complement(24505..25161)
                     /locus_tag="VXE45_000758"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0788830.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVANPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VXE45_000759"
     CDS             complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VXE45_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0788831.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFFNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETHKKVSKKIPK"
     gene            complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VXE45_000760"
     CDS             complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VXE45_000760"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0788832.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFACLADALKGQGL"
     gene            complement(27055..27363)
                     /locus_tag="VXE45_000761"
     CDS             complement(27055..27363)
                     /locus_tag="VXE45_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788833.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(27356..27997)
                     /locus_tag="VXE45_000762"
     CDS             complement(27356..27997)
                     /locus_tag="VXE45_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788834.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(27999..30029)
                     /locus_tag="VXE45_000763"
     CDS             complement(27999..30029)
                     /locus_tag="VXE45_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0788835.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREKVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSI
                     LGLGILWYQGALFMATVQLVIIALLLYGLILAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQYSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(30298..31197)
                     /locus_tag="VXE45_000764"
     CDS             complement(30298..31197)
                     /locus_tag="VXE45_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0788836.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VXE45_000765"
     CDS             complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VXE45_000765"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0788837.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSCKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(31829..32602)
                     /locus_tag="VXE45_000766"
     CDS             complement(31829..32602)
                     /locus_tag="VXE45_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0788838.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(32907..33800)
                     /locus_tag="VXE45_000767"
     CDS             complement(32907..33800)
                     /locus_tag="VXE45_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0788839.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VXE45_000768"
     CDS             complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VXE45_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0788840.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(34363..35577)
                     /locus_tag="VXE45_000769"
     CDS             complement(34363..35577)
                     /locus_tag="VXE45_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0788841.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(35733..36027)
                     /locus_tag="VXE45_000770"
                     /pseudo
     CDS             complement(35733..36027)
                     /locus_tag="VXE45_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36189..36641
                     /locus_tag="VXE45_000771"
     CDS             36189..36641
                     /locus_tag="VXE45_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0788842.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(36676..38064)
                     /locus_tag="VXE45_000772"
     CDS             complement(36676..38064)
                     /locus_tag="VXE45_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0788843.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            38130..39092
                     /locus_tag="VXE45_000773"
     CDS             38130..39092
                     /locus_tag="VXE45_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0788844.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(39121..39279)
                     /locus_tag="VXE45_000774"
     CDS             complement(39121..39279)
                     /locus_tag="VXE45_000774"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788845.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     NHTYGKAT"
     gene            complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VXE45_000775"
     CDS             complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VXE45_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0788846.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(40778..41377)
                     /locus_tag="VXE45_000776"
     CDS             complement(40778..41377)
                     /locus_tag="VXE45_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0788847.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(41379..42476)
                     /locus_tag="VXE45_000777"
     CDS             complement(41379..42476)
                     /locus_tag="VXE45_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0788848.1"
                     /translation="MLERLKSIHYMFWVSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     EAMTSMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(42476..43213)
                     /locus_tag="VXE45_000778"
     CDS             complement(42476..43213)
                     /locus_tag="VXE45_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788849.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(43215..44099)
                     /locus_tag="VXE45_000779"
     CDS             complement(43215..44099)
                     /locus_tag="VXE45_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788850.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(44086..44280)
                     /locus_tag="VXE45_000780"
     CDS             complement(44086..44280)
                     /locus_tag="VXE45_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788851.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(44277..44483)
                     /locus_tag="VXE45_000781"
     CDS             complement(44277..44483)
                     /locus_tag="VXE45_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788852.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        12879 a        10500 c         8552 g        13134 t
ORIGIN      
        1 tttaccacat ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaaccctc
       61 gggttctctc attctctctt attctactgt ttcttccaca gtttcaacgg cagtatccac
      121 aactacttct gttgtttctt catttccttc ttcctctact ggaggattaa ggtattcttc
      181 ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc ataccagtac cagctgggat
      241 gatcttaccg atgataacat tttctttaag tccaaggaga tggtctttct taccacggat
      301 agctgcgtca gtaaggacac gagttgtttc ctggaaggaa gccgctgaca agaaactgtt
      361 tgtttcaagt gaggctttgg taattcccat aaggactggg cgacctgtcg ctggaactcc
      421 acctgcgata aggacatctt tgttggcatc tgtaaagtca ttgatatcca tgagggtacc
      481 catgagaaga tctgtatcac ctggatccat gacacggact ttacggatca tttgacgaac
      541 cattacctcg atgtgtttgt caccgatttc taccccttgg ctacggtaaa ctttttgtac
      601 ttcaccgaga aggtacgttt caactgacaa gacatcacga actgcaagga gacgttttgg
      661 ttggatagaa ccttctgtca gagcagcacc acgcgctact tggcccccaa cttcgacacg
      721 catacgagct gtaaatggaa cgacatattc accttcgcca gtttcaccct taacaaagac
      781 tttcttggta cgagttgatg catcttcttc gatagcagta acttgtcctt taacctctgt
      841 aataaccgct tcccctttag gattgcgggc ttcaaagatt tcttggacac gaggaagacc
      901 ctgagtgata tcggtatttg aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg
      961 tgtaccaggt tccccgatag attgggcagc gattgtacca actgcttcac caacttcaac
     1021 cgcatcacca gtcgccaagt tgataccgta acagtgacgg cagacaccgt gacgagtgtt
     1081 acatgtaaat acagaacgga tagtcacttc ttccacacca gcattgacaa tttcacgcgc
     1141 cttgtcttct gtaatcaatt catttggacc aataatcact gcaccagttt ctggatgttt
     1201 aacagttttc ttagtgtaac gaccgttgag acgctcttcg agagactcga tcatctcttt
     1261 tccttctgcg atagaacgga tcaagagacc acggtcagtt ccacagtcgt cctcacggat
     1321 gataacgtct tgggcaacgt cgaccaaacg acgagtcaag taacctgagt cggctgtctt
     1381 aagggccgta tcggtcatac ctttacgagc accgtgagtt gagaagaaca tttccaatac
     1441 cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc cattcggagc
     1501 agccatcaga ccacgcatac cggcaagctg tgagaagttt gagatgttac cacgggctcc
     1561 agagtccatc atcataacga ttgggttctt aggatcttga ttagcaatca agcgtttctc
     1621 aagtttttca cgggcagcac gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt
     1681 gatcatacca cgacggaatt gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat
     1741 gatttcagcc ttgtcatcaa cgactgggat atcggcaata cccactgtca atcctgcaag
     1801 agttgagtgg tggtaaccga ggttcttcat gcggtcaagt agggcagaag tttctgtcgt
     1861 acggaaacgt ttgaagattt cagcgatgat atttccgagg tttttcttct tgaatggagg
     1921 gttgagctca agattgctga tagcttcctt gatagctcca ccaagtggca agaagtattt
     1981 agctggaaca ccttctgtca agttggcatt gtttggttct tgcaagtatg gtagcccctc
     2041 tggcatgata tcgttgaaga gaattttacc aactgttgta agcaagacct tatgtctttg
     2101 ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg
     2161 aacataacca ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga ccattccttc
     2221 accttcgcga ccagcttctt ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga
     2281 tggagtaact accggtttcc catctttcgg gttcaagatg tgctcagcag ctagcatgag
     2341 gatacgagct tctgcttgtg cttcttctga aagtggtacg tggatggcca tttggtcccc
     2401 gtcaaagtca gcattgtagg cttcacagac aagtgggtgc aagcgaagag ccttaccatc
     2461 aattaagact ggctcgaagg cttggatacc caaacggtga agggtcggtg cgcggttcaa
     2521 aagcactggg tgttctttaa tcacttcttc aaggatatcc cagatacgct catctccgcg
     2581 ttccaccaag cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg
     2641 catgacaaat ggtttaaaga gttcaatcgc catttcacgt ggcacaccac attggtacat
     2701 cttaagagtt ggaccaacgg cgataacgga acgtcctgag aagtcaacac gtttaccgag
     2761 caagttttga cggaagcgtc cttgtttacc tttaagcatg tggctcaatg atttcaatgg
     2821 acggctacct ggtcctgtga ttggacgacc acgacgacca ttgtcaatca aagcatcaac
     2881 tgcttcttga agcatacgct tctcattttg aacgatgata cctggtgcat ttaactcaag
     2941 caaacgagcc aaacggttgt tacggttgat aacacggcgg taaaggtcat tcaagtcaga
     3001 tgaggcaaaa cggccaccat ccaactgcaa cattggacga agatctggtg ggataaccgg
     3061 aaggatgtta agaatcatcc attcaggttt gtttccagac ttgtaaaagg catccaaaac
     3121 atccaaacga cggatggctt tgacacgttt ttgtccagta gctgttttca attcttcttt
     3181 gagttcagca atttcttttt caagatctac ttgcttcaaa aggtcttgga tggcttccgc
     3241 acccatcttg gcaacaaatg aaccataacc atattcacgc aagcgctctc ggtattcgcg
     3301 ctctgtcatg atagacttgt gctcaagtgg tgtatcctta ggatcaatca ccacataagc
     3361 cgcaaagtag ataacttcct cgagggcacg agggctcata tcaagggtca agcccatacg
     3421 gcttggaatc cccttgaagt accagatgtg agatacagga gctttcaatt cgatatgtcc
     3481 catacgctca cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat
     3541 tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat tcccagtctt ttgtaggacc
     3601 aaagatcact tcatcaaaga gtccttcacg ttctggtttc aaggtacgat aattgattgt
     3661 ttcaggtttt ttgacttctc cataagacca tgaacggact ttacttggag aagctagggt
     3721 gatttgcata cttttaaaac gatttacatc aaccactatt tcttcccttt ctattctaag
     3781 tgaactgctt attcttgttc agcagcttct tctgttgctt ccgcttttgt tgctttctca
     3841 gcttcttcag cttcaaaggc tgctttagcc tcttgggctg ctttttcgcg ggctttttca
     3901 aggtcatcta cgtggatgac atcttcgtcc attccttcat ccaagtcgcg aagttccact
     3961 tcttggtcat cttcgtctag gacacgcatg tcaagaccaa gagattgcaa ttctttgaca
     4021 agaactcgga aggattctgg aacacctggt tttggaattg gtttgccttt tgtaatagct
     4081 tcataggctt tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat ttcttgaagg
     4141 acatttgacg caccgtaggc ttcaagagcc caaacctcca tctcaccgaa acgttgtcca
     4201 ccaaactgag ctttacctcc gagtggttgt tgggtaacag ttgagtaagg tccgactgaa
     4261 cgcgcgtgca atttatcgtc aaccatgtgg tggagtttga tcatgtacat gactccaaca
     4321 gaaacacggt tatcaaatgg ttcacctgta cgtccatcgt aaaggattgt cttggcatcg
     4381 ctatccatac ctgcttcttt aacagttgac caaagatctt cagaacttgc tccatcaaag
     4441 actggtgtcg caatgtgaat accaagagta cgagctgcca taccaaggtg aagctccata
     4501 acctgaccga tattcatacg tgatggcacc ccaagtgggt tcaacatgat gtcgactgga
     4561 gttccgtctg gaaggtaagg catgtcttct acaggaacga tacgagagac aacccctttg
     4621 tttccatgac gtccggccat tttatctccg accttaatct tacgtttttg agcgatgtaa
     4681 acacgaacca acatgttaac acctgattgc aactcatctc catttacacg tgtaaagatc
     4741 ttaacatcac gaacgacacc atcggcaccg tgtggtacac gaagagaagt atcacgcact
     4801 tcacgagact tgtctccaaa gatagcgtgc aagagacgtt cttcagctga aagatctttc
     4861 tcacccttag gtgttacttt acctacaaga atatcacctt ctttaacctc agcaccaata
     4921 cggataatcc ccatttcgtc aaggtctttg agggcatctt caccaacgtt tggaatttcg
     4981 cgagtgattt cttcaggccc aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg
     5041 tgaacagatg tgtagacatc gtccttcacc aagcgttcgc tcatgataac ggcatcctcg
     5101 aagttgtaac cttcccaagt catgtaggca acgattgggt tttgtccaag cgccatttct
     5161 ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac atcaccaact
     5221 tttacgagag tgcgttggtt gtaagcagta cctgagtttg aacgacggaa tttttggatg
     5281 tggtaaacat ccaatgaacc atcttcacga cgaacttcta ccttgtcagc atctgcgtaa
     5341 gtaactttac catcatactg agcaatcaca gccgcaccag aatcgtgggc tgcttggtat
     5401 tccataccag taccaacgta aggtgcctga ggattaatca atggcacagc ctgacgttgc
     5461 atattggctc ccatgagggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacctg ttttggtgaa acgtccatgt agtcaacaat attagctgga
     5581 tactcttggt tgaccccttg gtgacgtccc atgacaatct tctcagcaaa ggttccatct
     5641 tcattcagac gagagttagc ctgagctaca gtatattcat cttcttcatc agctgtcaac
     5701 caaacaattt cgttcgtgac aacacctgtt tcacggtcaa ccttacggta tggtgtttga
     5761 acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa accgatgtta
     5821 ggtccttcag gtgtttcgat tggacacata cgaccatagt gagtgtagtg cacgtcacgc
     5881 acttcatatc cggcacggtc acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt
     5941 ttgtgagaca actcagaaag cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa
     6001 ccaaagaatt ctttaactgc agctgttaca ggacggatat tgataatttg ttgtggtgtc
     6061 aagacttcat tgtcctgaac agacatacgt tcacggacat tacgttccat acgagaaagt
     6121 cccaaacgta cttggttggc aagcaattca ccaaccgcac ggatacgacg atttccaagg
     6181 tggtcgatat catctacacg gccaagtcct tcagccaagt tgaggaagta gctcatctca
     6241 gcaaggatat ctgcaggagt caccgtacga accttgtcat ctgggttagc attaccaatg
     6301 atcgttacga cgcgatctgg atcagttgga gcaacaacct tgaatttttg aagaacaaca
     6361 ggctcagtca caacggctgc atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc
     6421 aaatggcttt caatgctttc aatcacgcta cgagtcataa tcgtaccagc ttctaccaag
     6481 atttctccag tttcagggtc taccaatggc tctgcaatgg tttggttgag caaacgtgtt
     6541 ttaacattga gttttttatt gattttgtaa cgaccaactg ctgccaagtc atagcgacgt
     6601 gggtcaaaga agcgagccac aagcaagcta cgtgagcttt cagctgtctt aggctcacct
     6661 ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc cattggattc
     6721 ttgtggatat ctttttcaac agtgttgcga accaattcgc tgtcaccaaa gatatcaaag
     6781 atttcatcat cacctgagaa accaagagca cgaaccaagg ttgtaaatgg aatcttacga
     6841 gtacggtcga tacgagtgta ggtgatatct tttgagtcgc tttcaagttc caaccaagct
     6901 ccacggttag ggataacagt tgaaccatag cccaccttac catttttgtc tactttgtcg
     6961 ttaaagtaaa cacctggtga gcggaccaac tgagaaacga taatacgttc accaccattg
     7021 atgatgaaag tacccatttc tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc
     7081 ttgatttcgc ctgtttcttt attgatcaaa cggaaggtta caaaaattgg tgctgagtag
     7141 ctagcatcgt ggatacgagc ttcttctagc gtgtattttg gttccttgat ttcatatcca
     7201 acaaattcca actccattgt gtctgtgaag tttgaaattg gcaatacatc ttcaaacact
     7261 tccttaagac cgtggtctag gaaagctttg aatgagtcag tttgaatttc aatcaaattt
     7321 ggtaagtcaa gaacttcttt gattcttgaa aaactacgac gggtacgatg tttcccgtat
     7381 tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat aagttccaag ccttgtcaat
     7441 caggcttttc taatcgtcat atggttgtaa accccttatc accgtgtcct cttgacgaat
     7501 tttcagaatc tttaagcctc tgttacaaat gctcataatc ttgaaaaaaa gcacaaaaag
     7561 agcagctaaa tctgactttt tcagaagatt taactgctgt gagccttgtc tggacaatat
     7621 ttcagacaaa acctacgaca aatgattacc catattatac cctatttagc tagatttttc
     7681 aaggggtttc agtaggtttt tggtaaattt tttcccatag aaaacttggc atcacattcg
     7741 aatcacgcta tggtacaaaa aactgaaaaa actattgact gaaaatcatt ttcaaggtat
     7801 aataataaac gttaaggcgg tatagccaag tggtaaggca cggctctgca aaagcttgat
     7861 cgtcggttca aatccgtcta ccgccttcta taacttgatt tatcaggttt caaatgaaca
     7921 gaaagcccaa tttgaagggc ttttcttatt ttccctcgaa taaatacgta taactttaaa
     7981 aacttttgga gcgagtttgt ggcagagttc tttccatggc ataattccct tttgaaatca
     8041 attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct agtttattct gtttcttctt
     8101 ctatttcgac ttctgtgatt tggactttta ccttggtaac acgtccattc ttcactttat
     8161 cattggttaa gataaactgt ttgttttggc tgaccaattc atagctgagt ttctcagtcg
     8221 ttggaatagt tcccactcct gtcaaataat aaccagcgat ggtatcaacg tcatcacttt
     8281 ccagttcaac atcaaagtaa ttattgaaat cattgagggt catagttcct tgaacaatgt
     8341 aggtatcctc gccaatctga tgaacatcta ttgctgcttt gtccgtttca tcatcaattt
     8401 caccaacaat ttcctctaag aggtcttcca aagtcaccaa accagccata ccaccgtatt
     8461 catccagcaa gattgccatt tgtctttggg tatttcgcag ttcttttagc aagtcatcca
     8521 caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat tctcttccaa acaatattgt
     8581 caaaaccgtc cacaaagcct gccttaagga gactcttggt gtgaatgatt ccaattacat
     8641 tgtccttatc cccatcataa accgggatac gagaataatt ttgttttaaa atactttgga
     8701 taatggcttg actatcatcc tgaatatcca ccataaaggc atccgttcga ggcaccataa
     8761 cctctcgtgc catcagttca tcgagcgaaa agacaccttg tagcatctca atctcatcag
     8821 catccaatgt ttcttcacta tttgtcagca tataggcaat ttcatcacgg gtcatctttt
     8881 catccgcatc atcgaatgac ataggagtca aatggctcaa gaaattggtc gaagcagcta
     8941 aaagccaaac aaaaggactg actagttttc cgatcccaat gataatcggc gctgtacgaa
     9001 ttgccaaggc atcctttaga ttaagagcga ttctcttagg atataattcc ccaaaaacga
     9061 tggaaatata ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt gctgtttcgc
     9121 cattcccaag ccaagaggca atcacacgtc ctagagtatt agttaaactc gcccctgata
     9181 agattgtaat cagggtgatt cctacctgaa tggttgataa aaagtggtta ggattttcta
     9241 gtaccttcag caggcggatg tagcgtctgt ctccttcttc cgccttttgt tcaactcggg
     9301 cacgattaag agaaaccatg gccatttctg tggctgagaa aaaggcattt aataccgtca
     9361 agataaacaa taaaacaaat tgtagcaaca aattctgact acttgggtct tccatagttc
     9421 ttctcctaaa atagtatctt atcctttatt atatcacaaa atttaatcca atacatatta
     9481 ttttttctta ccgtaacttc tcaaagtaac ttccatctct ctcccaaaac tggaagttag
     9541 ttttagaagt tgctattttt tcttagtacc tgttctagcc ctgcttaaac tagtaaaaag
     9601 aactcctaca tccataagtg acataggagt ttaggcttat cttttactga gttacagtta
     9661 cttctccagt tcggtaatcc agttgaagtc ccttttgaac attgggaact agaacattga
     9721 attccaattc tccatccgaa gacttggctt caatctgtga agctgaggga actaaatcct
     9781 cgtttgaagc gtagtaaagg gttacacggt aacggacacg cttgttttgg tccaaggctt
     9841 tacgcacctt gctttcatag tagttttgac cagtcgaata ctcggcttgt gcctgatttg
     9901 cccaggctgt ctgaacagca atgtttttag gattgcttgt tgaggcatca aaaccatcca
     9961 aaccaccgat taaggcatag cctaacaaat gacctctatc gactgcatgg gtataagagc
    10021 cctttagatt cttgacctga tgccaacctg gaggagtcca agaagttgaa ccattcccag
    10081 tttctttacg attcttgtac tgacgagtgg ccttagacaa gagggcatta gctacggttg
    10141 gaacagtttc cttgcccact gtctttgttt tattgtcagc gtagggctta cttgaaacct
    10201 tggcatctag atttgtttta ttaccattga cgataaaagc acctgagcca ttccactcca
    10261 gactcccctt tatttgactc ttgactgcgt ctgttaagac actctctgcc aatgcttgac
    10321 taggagcttc agacgcttgt tttttctgac taagattggt tttgggacta ttaggtgccg
    10381 acggcatctg cttgatataa tagctccctg tagacaaaag caataacact agcagtccga
    10441 ttagtgtctg tcttgttttt ttgttcatat ttctccttat ctttagaaaa aggctggttc
    10501 tccagcctaa tttcctgtaa atttatgaat caattcctgc cattttgctg gagacaggat
    10561 agcccatgga tcttgaccct tgcccaagat tccataacct accattaaac cgattcctag
    10621 agccagagta cctaaaatca gtactatgat gactaaaagt aaacgcttga ctacgtagct
    10681 tgatttctta ttcatcttca tcacttgcct caatccgctg aatcttagca cctagctgcg
    10741 ccaacttctc atggaaaccg tagtaacctc tatccaagtg aaccaattta ccgaccacag
    10801 tttctccctg tgctaccaaa cctgtcaaaa tcaaggctgc actggcacga aggtcagttg
    10861 aaagaacttc tgctccctgc aaaggctgtc caccaacaat acgagctgta tcacggataa
    10921 tctcagaatg caagcccatg cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa
    10981 ctgtctccac catggttgat tcgccttttg caactgtcat caaggctgta aattgagcct
    11041 gcatatctgt tggaaatcct gggtggggca aggttttcac atgaacagct tttagatttt
    11101 ctagttgaga acgaacacga attccttcgt cttcttcaat tacttcaaca cccatttcaa
    11161 gtaacttggc aatcaaggga cggttgtgct cccagacagc gtctcgaatc aagacatcac
    11221 caccagtcat ggcagcagct accataaagg ttcctgcttc gatacggtct tggactacat
    11281 tgtgagtcgt accatgaagt ttctcaacac cagtaatggt tatagtctct gtaccagcac
    11341 ctttgacctt ggctcccatt tcattaagga gaatggctaa gtcaacaatc tcaggctcac
    11401 gcgcagcatt ctcaatcact gtcaccccat cagccagagt cgctgccatc atcaagttct
    11461 gcgttgcacc aacacttgga aagtccatat agatatgagc gccatgcaag cgttctgcct
    11521 tggcttcgat gtaaccagct gtctgactaa tcttaacccc catagcttcc agacctttca
    11581 aatgaagatc aataggacgg ctaccaatcg tacaaccacc tggcatggat accttggcat
    11641 gacccacacg ggcaaggatt ggccctaata caacgatgga ggcgcgcatc ttgctgacat
    11701 acttgtaagg ggcttcctca gtgatgtcgc cagtagcatc caccttgaca agatgagctt
    11761 cctcatcaaa gtcaaccttg gcattcaaac caccaactac ctgattcata ataaagacat
    11821 ccgacaaaat cggaacattc tgcaagacgg tctttccttc acttgctaga atagtcgctg
    11881 ccaacaaggg taagactgca ttttttgctc cctcgatcgt cacgcttcct accagacgat
    11941 tatcgccacc ttgaaccaca attttatcca tactcgtttc ctttactctt gatttcataa
    12001 taatcctcta agcgcttctt gccacaaatg atacaggcta ataaagaaag aactcaggat
    12061 gtagcctatg acaatgctaa aaaaggctac taataaacga acttttcttg tattatcatc
    12121 tgtcactttt aaaaccttct cccatctaac aagatccttt aaaaggtaaa aactcacata
    12181 aataaagaac atatgactac ttagagtgaa taataattga accatttgac tattatacca
    12241 tcttctctgt ttgtgcgcta gtttggaaac ttcactcaaa aattagggat tgtttttcaa
    12301 gtaatcaatc gcatcttgta gggttttaac gggcacgatt ttcatatccg tcttgattgt
    12361 tttagccgct tctagggctg tttggtagtt gtttttcgcg tccggatgcg ccttttgttc
    12421 ttcttcgcta acagggttat caggagcaaa gaaaatagca gcacctgccc tagccgaagc
    12481 tacaaccttc ttatcaatgc ctccaatgtc tcccacatta ccatcgcggt caatggtacc
    12541 tgtaccggca acaatacgac cattacgaag atctgggtga gctatttgag tatagatagc
    12601 tagactaaac atgagaccag cacttgggcc gccaatacca gctgttgaaa agctaattgg
    12661 gacattgctg attacctctg tacgatcaat caagccgatt ccaattccat ttttgccatt
    12721 ttccaaggtg ataatctttc cttctgcaga cttggtttgc ccatcctctt cataggtgac
    12781 cttgacggaa tcccctaatt tttgagaact gacgtaatca atcaagtctt tggaactatc
    12841 aaaggtctga tcattgactg ctgtgactgt atcagagata ttgagaatcc ctttaaaggt
    12901 tgaattatcc gtcacattca aaacataaac tccaaagtac ttgagttcga tatccttacc
    12961 agctgttttt agtccttgat acttggccat attttgcgat gtttgcatgt agaattgatt
    13021 gattcgcata aattcaacat cggaagaacc acctgtagtc tcctgagcac tacgaatatc
    13081 tgtaaaaggt gtcaaccaag cataaatcat atgagctaaa gtggcatgtt gaacaccaac
    13141 cgtaacgaat tgataggcac cagcttcctt atcttctgtg tcatttactt taaggacttg
    13201 gcgaatatct tccgaaccac ctggaacctc tatataataa ggcaagggca ctacaaatgc
    13261 caagaaagtc acaatcaagg ccgcaatgac gtataagggc catctaatct tttttttcat
    13321 ttcttatttc ctccaaaata ctctcgggaa catggcaggc aatatcctga ccaaacttca
    13381 aaagctctcg aacacctgat gaactgatat agagatgttc aggccggcta tgtaaataaa
    13441 tagtctctat atcagaagac agctgatgat tgtagtaatc aaaactagct tcatattgca
    13501 aatccgccgc attcctcaac ccccgtacta ggaaagtagc ccccagtctt tttgcaacat
    13561 cgaccaccaa ttcatcatga gaagccacga cttcaacatt ttccaaatgt cccaaagcct
    13621 tttctagccc ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg ggattaaaaa
    13681 aaatacccac ataaagctta tcaaaaagtc tgctcgcccg ttcaatgata tccagatgcc
    13741 catttgtcat cggatcaaat gagcctgtga ataagccaat cttatctgac atagactgtc
    13801 accttactaa ttccataaat cttttccttc cagataccca gacaggcaat ctcttctgga
    13861 agttcaacgg ccttatccgt ctcgcacaca accataacat cttcagaaaa aagctctctc
    13921 ttagccattt tttcaatatc tgctacgatt tgttccttgg catagggagg gtctaagaaa
    13981 acgaggtcaa attccccaga tacctgttcc aatgccctct ctgcatccat cttgaggagt
    14041 tgaaattttc caacttcctt ggtcatctgg atattttcag ccacgatggt ctgagcctta
    14101 cggtctcgct ccaccaaaac agcactggac atgccacgcg atactgcttc gatagataaa
    14161 ccaccactac ctgcataaag gtccaagact cgtccccctt caaagtaggg accaatcatg
    14221 ttaaaaatgg ctcccctaac cttatccgaa gtaggtcttg ttgtcttgcc ttctagtgtc
    14281 ttgaggggac gtcccccata gattcctgat acgattttca tactgtttat tataccaaat
    14341 tatagacaaa aagagaaaga aaaccgaacc ttgcggttcg attctctaca aaatattttc
    14401 gtaagtatcg cgtacttctt gaggccaaac acttgtttgc acttctccga tgtgtctctt
    14461 gcgaagtagg aacatggcca tacgagattg tccaattcct ccaccgattg tcaatgggaa
    14521 taggccattc aacaaagact tgtgccattc caattccaag cggtcttcat cacctgtaat
    14581 ttccacctga cgtctaagag tttcttcatc tacacgaatt cccatagaag acaactcaaa
    14641 ggctccacct aaagactcat tccagacaag aatatcacca tttagaccct tgtagccatt
    14701 ctcagactcg cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc
    14761 tggcaactcg ccaccgatac caatcaaaaa gacggctcca aattctttac aaatcgcatt
    14821 ttcacgttct ttcgatgtca agtctggata gcgttctacc aattcttctg tatggataaa
    14881 ggtgatttgt tttggcaaga tagactcgat gtcatagcga gcttcaacag ctagctcagt
    14941 caggcgaata gccttataaa tcttctcaac tgtttctttt agataaacga tgttacgctt
    15001 accatttggg ataaccttct cccagtccca ctggtcaaca taaacagagt gggttgcatc
    15061 caaggaatcc tcatctggac gaagggcttt catgtggaca aagagaccct ctccttcacc
    15121 aaagccaaaa cgagccaagg tgtggcgttt ccatttagca agtgagtgca ccacttcata
    15181 agtagcatca gggatttgga gaaccttgac cgatactgga ttttccacac cagacaggtt
    15241 gtcctgcatt ccgtcaccga ccttactcaa gataggacct tgaacttcga caacttctag
    15301 cttatctttc aaatactggg taaaagtgtt tttgacaaag gaaatttctt cttgttgatg
    15361 gataaaactt ttcttcatag acaactcctc aaaaatttaa taaacgtatt atacacctat
    15421 ttccaagaaa agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa cactgatttc
    15481 atagaccttt tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa
    15541 atcaagatag atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga
    15601 ttgttcatag gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa
    15661 aaccatggct acactaatca tataatcaaa gaagccacta gccaagaaaa tattgactac
    15721 catagcaatc agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc
    15781 tttcttggta aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa
    15841 ggcagataaa actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt
    15901 taaaacggag taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct
    15961 actggcaacg aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc
    16021 ctgcatcaac aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa
    16081 agcagatagt ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag
    16141 acctgcacgg tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt
    16201 tccttgatta taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg
    16261 caactgcaac attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg
    16321 cactttcagc cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat
    16381 tttctataga aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca
    16441 ctgggatagc taccttttta gtttcgtcaa gaagcgctgg actagtcatc cggtaaatgg
    16501 gcagatggaa atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg
    16561 acttatctga aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc
    16621 ctacattacc gggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag
    16681 cttgtcctac ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg
    16741 ccaaatctag caaaatatcc tctgaaatcc agacagtttg cggaaaagca gctaactgat
    16801 ctcgataatt ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt
    16861 caaacaagtg ccagccttca atcaaatagg cagacttgcg gtattttttt tggtgtaatt
    16921 tcttggcatt ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat
    16981 aacacaatca aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca
    17041 gggagtcggc tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg
    17101 tcgagtatgg aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc
    17161 tatcatggca aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag
    17221 ctacttagat gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta
    17281 ggtctccaga actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt
    17341 aaagaaggaa taaaaacagt gaaatctatt aaacgttttg cactctcagc tatgggagcg
    17401 gctatgttgc ttgtcttgac tggttgtgtc aatgtcgata aaaccacagg tcagccaaca
    17461 ggatttattt ggaataccat cggagcccct atggctgaag ctatcaagta cttcgctact
    17521 gataaaggtc taggctttgg tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt
    17581 atcttgccac ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac
    17641 gccctcaagc acgtccttga gccacaccaa acgcgtctca aagaagcgac tactcaagaa
    17701 gaaaaactcg aagcccaaca agctctcttt gctgctcaaa aagagcacgg tatcagcatg
    17761 tttggcggtg taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac
    17821 tttgctgccc aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt
    17881 tctccaagta tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt
    17941 tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg
    18001 agcccactca tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg
    18061 gttgtcggtg gtttcatgat gattctccag caatttatcg tcaactatat cgttcgtcca
    18121 aaacttcgca aaaaagtcca tgaagaactg gcaaagaacc catcaaaagc aagtgctttc
    18181 tcaacaccaa gtggacgaaa agacgttacc cctgaacaac caactgctat tacaagcaag
    18241 aaaaaacaca aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta
    18301 gctgatttgc taagtctttt tgcaagtcaa aagcccgatg tttccatcag gcttcttttc
    18361 tatccatgta cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg
    18421 ttcttgacgc gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt
    18481 tcacgccact tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt
    18541 ttgagggtct tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct
    18601 ggaactagca cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa
    18661 gccaagatat ttttattggt ttggctagtg acaatcttgt gctgttcttc gttgatttcc
    18721 ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa
    18781 cgcggtttat tacggaaagg aagagcacag gtgtccaagg tacagtggat tccttgttcc
    18841 ttagccttgg tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg
    18901 actgtaatcc cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca
    18961 tcatctaccg tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg
    19021 caatactggc aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca
    19081 tctactgacc caaagctttc tgtcgaatgc accatccctg tcacttgtcc ataatcaatt
    19141 gtttcttcag acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga
    19201 cttgaaggaa aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca
    19261 ttttcaatct attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt
    19321 cctcagggcg ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt
    19381 ccgcagaacg taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat
    19441 catgaattac cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt
    19501 tatcattgtt ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat
    19561 gggtcacgtt gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg
    19621 ctgaggcatc tacacctaga taggtacggt aggtttcctt cttatgagtg actcttgtga
    19681 ctagagcacc gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac
    19741 caagacctgc tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg
    19801 cgatatcgtt cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga
    19861 taaagtctaa cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac
    19921 gagccaactc tggataatag agatgggtca cggtattgga cgctaggaag gagtgaagcc
    19981 caaaagtctt ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg
    20041 tcatgccaaa cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc
    20101 ctccaggatt ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt
    20161 caatatcttc aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt
    20221 ccttgtctgg cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat
    20281 ggctcatcaa aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa
    20341 ttttcaaaat agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt
    20401 tccacgaaaa agcttggttg acagctcttg ccttctcacg aatccccttc tcatcataca
    20461 agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg
    20521 gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa
    20581 cctttagttc tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg
    20641 cttggttctt gacatcaata ttggttacct tcaagagtga cttgtagtca aactgctttt
    20701 cacgttcttc ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact
    20761 cgcgcaagag actaatcata ccgttgaccg ttccgccacc tttcaagaag tcatccacaa
    20821 tcaagacacg gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt
    20881 caccacttga acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt
    20941 cacggcgcac aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca
    21001 cacccttagt tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa
    21061 taatacgacc aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat
    21121 aaccacctgg caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt
    21181 ccttagcatc ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca
    21241 ctgtctggat atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt
    21301 ctgagatgga tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt
    21361 tataaggatt attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt
    21421 tcatttctat ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg
    21481 tcgctggtgg ttcaaaacac tgctttgaga ttgtcgatag aactgacaaa ccctgtaata
    21541 tacctgcata tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga
    21601 gtattcattt ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta
    21661 tcctaaaaaa tgctcatttt tcttaaatta ttaatctaaa tctggtttat agaaggaacg
    21721 attatccata gcgaagattt tattggacat ctctccttta tccaccaaag ccagagctgt
    21781 tgacatcatc atcatgcttg catccagatt gtcaatcata tggataatct ctgcctccat
    21841 aatacgtgga cggactggac ttccatattc aagcaagccg tggtgactga ggatgacatg
    21901 acgaagcaaa acgacttctt ccttggtatc gtcgatgccg agttccataa ctgtcttggt
    21961 aatttcgcta tcaatgagag cgatatgtcc aagaagattg cctcgcactg tgtactctgt
    22021 ctggtctggc cccgtcaact cgatgacctt agctaagtca tgcaacataa tccccgcata
    22081 gagcaggctc ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgcaccat
    22141 ggtcgccgta tgataggcca agcccgtttc aaaggcatgg tggttggtct tggcagctgg
    22201 ataggagtag aattccttat catacttggt gtagagattt cggacaatcc gttgccagac
    22261 aggattttca attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac
    22321 tggtgacttg accttgaaat cagctgggtc attgggttca ccagcttgag gcaggcggag
    22381 agtaatttga ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac
    22441 aaccttacct gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc
    22501 aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg
    22561 cctcaggtca gctgatttga ttaggtaaaa gccttcaaat aactcatctt ttttcatgtg
    22621 actaatcttc atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac
    22681 cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata
    22741 attcatcaat attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac
    22801 caaacttgcc aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct
    22861 tttggatatt aagggtcttg aaaccaactg atagggagtt aagaagggct gatagggtac
    22921 ttggtcctgc aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc
    22981 ggacgatttc tgagtagaga ccttctgtcg gaacaaacaa gattccaaaa ttggttgtcc
    23041 gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa gcgcttgacg cttgctagga
    23101 gtgacttacg acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc
    23161 ggtaataatc tgccagtgga aacttagagt caattggaag atagacgtat tcttggtcgc
    23221 cttgtccggg taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt
    23281 attctcgttc gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt
    23341 ctcccagaat ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac
    23401 gggcaactgt ctgcatttct ccaagaccac gattgacaga ctccagttgt ttagaaactg
    23461 tctcaaagga agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct
    23521 ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg
    23581 tcttgtctct agtttggagg agattatctg tcatttcttg acggacttgg gtcaggcctt
    23641 ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac agccacttcc aaatcttttt
    23701 ggtctaactg gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat
    23761 gatctgcctg atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc
    23821 aaatcagaaa gagaccagct aggttggcaa ttaataatag aataagtaaa ctttccatcc
    23881 tacctcctat ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact
    23941 tccctatcta tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc
    24001 aactcatact tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga
    24061 tagtcgtagt ctgaacgagg ttctagctga ctggtccctt ctggacaata agtaatcaag
    24121 ttttgcccat cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc
    24181 agaaagacat tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc
    24241 tgagcctgag gattttgttc aaagatggtt aagagagcca attccaaatc ggtatcatct
    24301 ttttctggtc gtgcttggac aaaatgctgg gcacgttttt gaatcacctg tcgctcttct
    24361 tcggtcacag aatcaaaatc cccaactgct agagcaagag gcaagtcttc ttccaagacc
    24421 cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg
    24481 tctccgcctg caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc
    24541 attgacatct cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt
    24601 agcttgggca atagtttggt catcaatccc accatccact tcgatttcaa agttcaaacc
    24661 tttttcctca cgaagagcaa ccaactcacg aaccttatcc atggtttctg gcagaaaggc
    24721 ttgcccacca aaacctggat taaccgtcat gactaaaact tggtcaacta gatgaaggac
    24781 gtgcttgatg gcttcaactg atgtgccagg attgataacg actgaaggct taactccgag
    24841 tgaacgaatt ttttggaggg cgccatgaat atgaggcgtt gcttctacat ggatactgat
    24901 gatgtctgca cctgcgcgcg caaagtcttc cagatggtgt tcaggattcg ccaccatcaa
    24961 gtgacagtca aagaccatct tactatgtgg acgaagtgct tcaaccacac cggcaccaaa
    25021 actgatttgt ggcacaaaat gactgtccat gatatcgata tgggcatatt ctgccccagt
    25081 tgcttctaga cgtttgattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg
    25141 agcaatcttg tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt
    25201 tatgggtttc tctacgattt tcaatttcac taaggaattg caggtaattg tcaaaacgga
    25261 aggttgcaat aacaccctct tcaacagctg gtttgacggc acaagacggc tcatgggtat
    25321 gggtacaagt acgaaactta caatctcggc tgacagtagc aatctctggg aaagcctgat
    25381 tgaggtcttc agcccttgat acttcatagt ccagagatga aaagcctggt gtgtctgcga
    25441 ttttaccccc attgaggttg aaaaaactaa cagctcgagt agtatggcgc ccacgaccca
    25501 gactgtctga gatttctcct gtttcaagat tgaggtctgg tgcgattttg ttgagaagag
    25561 ttgacttccc aacacctgtc tgccccataa agaccgtaac cttgcctgtt aacaaagaca
    25621 ggagttcctc tttactggtc acaaagtcat agccgatgtc accataggtc tgctggtaaa
    25681 aatccagttc tcccctatct tccaacaaat ccattttgga aatatagaca atgggatgga
    25741 tgcccttgtg ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt
    25801 ccttgacgga catgattact acagcttgat cgatattgac aataggcgga cgaaccagac
    25861 tgtttttccg ttcgtgaatt tttaggatat agccttctga attttcctcg gcagagaaat
    25921 ctacccagtc cccaacataa ggggtatggc cttttttacg gaaattccca cgcgcgcgtg
    25981 tttgataaac ctggccatca ctctccacat agtagaaacc tgccaaggct ttaatgattt
    26041 gtccctgcat cttagagtcc ttgcccttta agtgcgtctg ctagacaggc aaattctgcc
    26101 aagctgagag cttccccacg cacacttggt gacaagcctg cctggtccaa agccttggtc
    26161 agcttgtcct tgacctcttc agtcttacca aagtaacctg tcaagttatt ccacaaggtc
    26221 ttacggcgat gggtaaaact agccttggaa accttaaaga agaagttctc atcttccact
    26281 gctacagctg gctctggacg gcgcaccatt ttcaagatgg ctgaatccac atttggcgct
    26341 ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta atactgcacg
    26401 gcgatagaca agctaccgta agccttggtg ttaggctggg ctgaaatgcg gtccgctact
    26461 tctttctgca tcatgaccac aaactcacta aaaggaatcc cactctcaat caagtgcatg
    26521 agaataggcg tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg caggttagga
    26581 tttttaaaat tttggatatg ttgcgccaaa tcaaccttga gaatatcttc gttaactaca
    26641 gtcacattat caaaatcacg cagggtatct gccaaaattg gcaccaaacg gtggtcaatc
    26701 tcaaaagcca tgacttgggc tgcacgctca gccagaaact ccgtcaaggc accaatacct
    26761 ggcccgattt cgatgacatt gacctggtca tcaatttcag ccgtatccac aattttttga
    26821 aggatattgg tatccgtcag gaaattttgc ccgaaggact ttttaaaggt aaaaccgtga
    26881 cgctccagca ctgccttggt cacgctataa tctgcaattc tcatctattc tcttttctat
    26941 tatctgttac tactattgta acacattccc cttgtatttt gggaatgaaa atcataccaa
    27001 aaaactatct ttcctcatga agaaagatag tcttggaaat ctttaaaagt ggccttaaca
    27061 gttctctcga aacatgcgtt caaaaaaatc agcttcttga taacttcgat tttcgggtag
    27121 ggtcaaatcc acatcctcct ccacatcatc cactgtcagt tcaaccgtct gaggtaaatt
    27181 tttcaaacga taatgctttt gcctttgccc ttcaatacta gcaaaatcaa gcaaatagcc
    27241 atgtactcgg atttgaacca aaaggagatg attggtcata ttttccatga tgaggatatc
    27301 ttctaaacca cctctggcac taggataatc agatactctg cgaatacgga ttttttcaca
    27361 catgagcaag tttcctcata tcaatgattt catcagcctt attccagact aggggattat
    27421 gggtcgcaat gatgatcatt cgattttcat ctttcaaatc caccaagaga ttcataacct
    27481 cctctgaatt ttcaggatca agagctgctg ttggttcatc tgccaaaatc aagggtggat
    27541 ttttcaaaat agtcttagca agggcaactc gttgggcctc tcccccagat aaagtataaa
    27601 ttttttgttc taaatccaaa taccctagat taactttttc taaagccccc acttgccttt
    27661 ccaaacgttc tacttttgag attttctgac caacaaaacc caaatccaaa ttttctttga
    27721 ttgattggtt ttctaagagg ccaaaatttt gaaagagata gcccatctga tctcgaaaat
    27781 actcacgagt gggaatggtt tttaaatctt tcccctgata gagaaccctt cctccatcta
    27841 tcttttctag ctttcccaag atattcagca gcgtcgtctt tccgcttcca ctctttccga
    27901 ttaaggcata aaccttgccc ttctccagct tgagattcaa accagagaaa atcgcgcggt
    27961 cattaaattt cttttccaat ccttgaatat caatcatctt attttccttt caatactgcc
    28021 atgctaccag cttcttcttt tttgtcctgc cttactaaaa tcaagagggc gttaagcgta
    28081 aacaaagcta caactagagc gctaatcaaa ccatctcttg tcaaaatact agataggact
    28141 aggccaagca agagaactcc tccttgcgcc agtaaatact tgccatgaag ctcatagatt
    28201 gtcataccag caagacgttt aatcataagc tcccgtctga actgctcaaa atagagaaga
    28261 ttcatggaat caaataacaa gatagccgta gacagggtca aaatcgtccc aataaggaga
    28321 gagtaaaact ccacccgttt gtcatttagt accttggcaa aaaatagctg gctttttacc
    28381 aagtaagaaa ccttgtgata cagaccttgc tcttttagag ctgtgatgct gtctccatat
    28441 cgatctagtt tcaaggcact attagccgta gttccccaca acatccctgc aacaggtctt
    28501 gttccagtcg cttgcggcgt tagaactaca ataatcggat cttttaggta ctggcgtgtt
    28561 gtcttgtacc catcattata gaggaaacgt tcctgtcctg tttctgtaaa agctagcctt
    28621 acctgtggga agtagtgttt ctgactcgtc acttctacac tttcagatga aaagttttgc
    28681 aggtaatctg taaacaatcc ttggtagtag gcagactgct ctcgcaagct ctcaggcaag
    28741 atcagcccaa actctccctc agacaagttt tgcatcttgt ccataaactc tgaagaaacg
    28801 gtaatctttt cttctatcag atagcgtggt gagacataga taacattccc tgacggtgtg
    28861 tagtcactga gacgattacc atctaggtcc acttctgctc catctgagaa attgtcaaca
    28921 ttgctcataa tataaaaaga gtctgtattg gctaaccgtt cttcagtaaa tgtctgccac
    28981 tcacgattat ccttacgcgt tccttcttca tcggcaaatg cactagacca accaaaggat
    29041 agacggtaac ggtctgagta ctggctccat ttattgctag ctctctccat ttcctgcatt
    29101 tcacggtagt ggggtaggag agctgtcgca ctcgatccga ccaccaatac agctaagagt
    29161 tgccccacca tcatcaatgt catcatacgt ttgagaggga gtttcccttt caatagatcc
    29221 accagactat tttcctgtaa accaagtaga tagacgacac ttagtaaggt agaaatccct
    29281 gccaagatca atccataaag tagaagagca atgatgacca gttgcaccgt tgccataaac
    29341 aaggcacctt gataccagag aatccccaat cccaaaatac tggataccag cactgagcag
    29401 ataagctgtc tcacatcttc taacactggt ctgagagcaa ctccaaacaa gctctcacca
    29461 gctattaagc gaatccctgc ctgacgaagg gatttgatcc gataaatcag ggtcagactc
    29521 ataaaggtca gcagaaaaat agctaaactc agtagcacca taggggtggc cgtcaatagt
    29581 aagactatcg aaaatggatc ttctccattc gaaacaaagc cttgatagcc aagttctttc
    29641 aaggtggtct gtaagctcac tccatccaaa cttcctgaca caatcaagta agaccctaat
    29701 aaatcactcg tttctgcact ctccttggag gaaatggtca gaccttctgg aagctctccc
    29761 tcaccataag tggcataggt aaagagtgtt tctccagctt catttggctc aacgattcga
    29821 cgggcgatga gactattatg ctctaccgcc aagtgactca aagcctctgt caccttttcg
    29881 cgactagcta ctggttgatt tatcatcatt cctgtcacat caacagaagg atagttacca
    29941 aataaaatct cttctcgatg gtcaacggaa gttatcacca tataaagcga taccaatacc
    30001 attgaaatca aaataaataa acgtttcatc atttcctcca aaaagttact tggtcactta
    30061 gtgagaaggt gaccacagtc actgcgatgt taagaagctt attaagttct ttctgctagc
    30121 aacatcttca aatatattat atccgttttt tcaagaacta tcaaggacat caatgtcctt
    30181 aaaatctaac tatttcatat tatttttagc ttatatctaa aaaaacagtt ctaaagacga
    30241 actttagaac tgttttgata cgaggacaag gacatttttg tcactgattc actatgttta
    30301 taaatatttt ttgacatcct cttgccattc ctctgtcaat ttctttacta gaaatccatc
    30361 tccaattagc ttcgcaaatg ttttagaaga ctgataaaat gattcagcta aactaaaatc
    30421 tctttctact cttaatgctt gcttccacaa aaacataaat acaagaggtt tcttttgata
    30481 atcttgagtt ttatccataa tttcttgtaa acacgataga taatcattaa aacaatcagt
    30541 tactcctacc ttttcaagac aacacattcc tgaaataaga gtatctctaa ttataaagta
    30601 attctctatt tgagttacct tcttctgttc caaaagaaag agcattagct tttcgatttg
    30661 atttataaat ttggcaagat cttttctaat gagcatttga taaaaaaaca aacgaatcaa
    30721 caacatatca tttgttgaat aaacttcttt ttctatgatc tgagacatat gttcctcaag
    30781 tattaactct gcatattcag gccttctagt tctagaagta tccaaacacg cctgcaatac
    30841 ttcacatgct aattgttctt ctttaggaag attatcaaag tatgttttat aaatctcttc
    30901 caaacacgct tccttcttat cgtactcctc ttctttacca tagattggtt cacgtaaaat
    30961 ctggtatttc aattctaaat aagcagaagg aagagctgaa aaatccggca taaggctata
    31021 aactggaact cctagccggc gagcaatata gtctaacttg ggcaaactcg gttgcgaagc
    31081 tccactttca attcgcgaca gttgacgaac tgtcagttct tgctcatctc cacaaaaatc
    31141 tggacgacta attccttttt ctatccgaat ctctttaatt ttttgaccaa ttaacatcag
    31201 acgcctcctc ttctacctgc ttcgaaaaat actgtgaaac ttaaaaaatt gtaacggtca
    31261 catctttcct actcataaga tttcatagct tcttccactt ctgccaaagt aaccccaaac
    31321 aactctaggc gtttgaggag ttgcttgccg ttagaatagc cgattcggag agtctctccg
    31381 agatattctc tacgcttaca gctgtctgcc cctgctagaa aaccaaggcg aatcaagtcg
    31441 ctacgactaa tgtcaaactg actctcatgt tcaaattgtt ctgtcacctg agctagagcc
    31501 gttttcaggt cttcatagct ggcatgctca attcccagag aacgcccctt ggtcttggac
    31561 ttgggaacag cttcatctcg cttgagaaag gcatgctgaa ctgttggaat gaccatcatg
    31621 atcatgcgcc gaatccgttc cccattaaaa tctgggtctg taaagacaat gactccatga
    31681 cgttggtgca ggcgctgaat ccgctctata tcctgagcat tgatggcaga acctcgagtc
    31741 tcataggtct ccacatcgaa ataacgtttg agattgaccg tatcatcacg cccttcaacc
    31801 acgataactt gagaaatttt ctctttcatt acttgctgtc cagtccaaaa attcgttctg
    31861 catttgcagt cgttgctacc gccagctctt ctgtcgtcat accacgcaag tcagcgataa
    31921 agtcgaccac atagcgagta taggctgttt tattttcacg accacgcttg ggtacaggtg
    31981 ctaagtaagg cgcatctgtt tccaccaaca tcttgtccaa aggtaactct ttagctgctt
    32041 cttggaggtc agttgccttc ttaaaagtca ccactcctga gaaggaaatg gtcataccaa
    32101 gatccacaaa cttctctgcc cactcaagcg tccctgaaaa tgaatgcatg ataccaccac
    32161 gaggaccaac gccctcactc ttgataatct cataggtatc ttccagcgca tcacgggtat
    32221 ggacaacaaa aggcaaatcc aagtccttag atagctgaat ctgacggcga aaaacctgct
    32281 cctgcacctc tttgggcgct gtcatccaat ggtaatctaa gccaatttca cctaaagcca
    32341 caaccttgga atgttttaac ttatccaaca agtaagcctc aacttcctct gtataagtac
    32401 cagcttctgt aggatgccaa ccaatagtcg catagagctg ctcatactca tctaccaact
    32461 ccaaggcatg ctcaatcgtc ggtttatcaa aaccaacaat attcatctgt gtcacaccca
    32521 tctcagcagc caaggcaatt tcttctgcct cacgacctgc aaattcttct acattcaagt
    32581 gtgtatgtgt atcaaaaatc atctcttcta acctcgtttt ctatcttcta ttataccaaa
    32641 aaagaggagg ggcacctaat ttttcggttt cccctcctct cttcaataga gagctattct
    32701 gctatctttt ctatccgata ttgcccatct cctattccac agttagagac agaagagatt
    32761 ggctacattg atagaatatt cctattcagc taaagtatgt gattatcttg ggttctcact
    32821 tttctcaccc atcactagga ttgatgactt ctcaaaatcc cccttataat ctaactttaa
    32881 gtagagaata gaattttcta gctgttctat tttctacgtc tagtctttct tcctagcaaa
    32941 gcaaaaccac ttgttgccac cactagacca agactagcaa gtgctgcact tgatgctgaa
    33001 cctgtgttag gtaattgttt gccagcaggt gactggtagg taacatcttg cattgttcct
    33061 gcagttgctt gcggtgcact tgttgtctta ggagcagcat taggagccac tggtctctta
    33121 ggaactgtaa ccatggcaat ggcttgcact ccaatcgttt ctgcttcctt cacatcttcc
    33181 atagttttcg cattttcaat ctctttgaga gctgcttgtt tttctgcttc cactcttgct
    33241 aaaagttctg ctttttcttt atcagaaagc ggtgcgcctt tgatttcatc ctgcttgtcc
    33301 ttggctgctt tttcaatggc atttttagct gattcttttt cagtagctaa ttgcttagaa
    33361 gcttgtgatt gagctgagtt ttgtgaacct gtgtgagctg atccacccgc ctggctacca
    33421 ccgccttcat tcgcattagc atctgagctt ccagtattgc ctcccttatc tccacctggt
    33481 gtattttcta gcttatactc tggtgtagct tcttgagtta cagattcacc tttcgcagat
    33541 tgttgaactg tatcttttcc tagaatcgtc actactgaac catctgggaa tgtgattgtt
    33601 gctgtaccat ctccagctac attgattgtc gctccgtcta atgctgaacc atttgcttgt
    33661 aaaatagcaa ccttaacttt ttcttcatct gttaaatgag ttatatcttt tacatctact
    33721 ctttgagcag gtgctttaac agttgatttt tcagcagtca gtttagtgct atcttgtgct
    33781 tttggatctt gtgctaccaa ttgatttcct ggaattgtaa tagctgaacc atctttaaag
    33841 acgattgttg ctgtaccatc tccacctact tcaactttat agtaaaataa aataataaca
    33901 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaaa cagaggtgta
    33961 ctattctagt ttcaatctac tgtaacatcg cttccgaatc cgtttgcatc tactgaactt
    34021 ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata gaattcgttt
    34081 ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata cgcgacgacc
    34141 atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa gtttacttgg
    34201 ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt ttagccggct
    34261 ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc acttttgtca
    34321 atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac gatactgttt
    34381 caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag gaaggtaaac
    34441 gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca agagaacctt
    34501 ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt acatattgcg
    34561 gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca aacctggaat
    34621 atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac caggaagaag
    34681 caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt gggccaaaac
    34741 gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc ccttaacatg
    34801 agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc ggtgggattt
    34861 tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca caggcgtatg
    34921 cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa tcaaatcgtt
    34981 ttgacgggca atctcaataa tctccagcaa gagttcctta ggataaaggg ctccagttgg
    35041 gttattggga ttgataagga caattgcctt ggtattggaa gtgatttttg acttgatatc
    35101 gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg catttcctcc
    35161 agctaggctg acagccgccg tccatagagg atagtctggc attggcacta agacctcatc
    35221 cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac catttccaag
    35281 gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact gcatgatggc
    35341 cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac gcgcattcat
    35401 aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg gatttcctgt
    35461 attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt ccaatacagg
    35521 accacggata tcataagcaa catgctctaa cttactagac ttgttatatt ctttcatctt
    35581 gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg cgacaagttt
    35641 actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg aggttaagaa
    35701 cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa acctagaaaa
    35761 aagcaagcct agaaaggagt cataaagaag attaaacatg aggaaaagcc cccatatcat
    35821 caagtaatcc caacgcccac ttcgttttgc aactagaaat aagattagat ggtagagtac
    35881 atgaaaaact aaaaatccaa taaaacttgg ataaagaagc ggtaccagac tctctaattg
    35941 acagatcatg atcacttcta ccaagactga aactaggata attccataat aaaggaaatt
    36001 tgatttttga aaagagtttt tcatcattct cccttccttc acttctttcc tgctatcctt
    36061 tcttttattt tatcatatat ttatatagag tttaagccct aatattcttt tgaaaaatac
    36121 tttttttgct ttacttctat agtgaaaagg tttacaatta tagtaagaaa atttcaggag
    36181 gtttcattat ggcacaacgt taccaaaata tcatggtcgc aatcgatggt tctaaggaag
    36241 cggacttggc ttttgtcaag ggagttcatt ctgctctacg aaacgacgct aaactcacca
    36301 tcgcacatgt cattgacaca cgcgctctcc aaagcgtatc cacctttgat gctgaagttt
    36361 acgaagaact ccaagtcgac gctgaaagtc tgatgaaaga gtacgaaaaa cgtgctaaag
    36421 atgctggggt agcagatgtt catatcgtca ttgaaatggg aaatccaaag accctgctag
    36481 cacgtactat tccagatgcc gaggaagtgg acctcatcct cgttggcgca actggtctca
    36541 acgcctttga acgcctcttg gtcggctctt catctgaata catactccgc catgctaagg
    36601 tcgatttgct ggttgtgaga gaacaagaaa aaaccttata atcacaaaga aaaggagccc
    36661 ctagctcctt tttgtttacg atttatttct ctctttatgg cgttcgtaag ccttgagctg
    36721 gcgctgcagt tcctttttaa tagcaggttc tggagcatat ttttcttccc aattatctgg
    36781 ttttaagatt ttatgggtca ctggatcaaa atgagccttg ccatctggaa aaattttccc
    36841 catattggcc tgatggacaa tatcaaaaat acgttctggg tccaccccca tcaagacaaa
    36901 actgccgtag gtgaagtaaa gcgtgtcaat caaggcatcc acttgcccta tcaaatcttg
    36961 ctgagcaggt gtcttcttgg ctactttacc tgctgcctta tcaagggcct gatgaagttg
    37021 cgatacagct tgaccaaaat cttcttcaga aggactggct gatcgaacaa actccaccaa
    37081 ttcttctatt ttaaaaccag ccctatgggt tgcaccctct aaatcccaag ctcgaggttc
    37141 ttcttgggtt cgttcatcca tcatgtggtg gaaggtcttg accttattga aatgatagtc
    37201 acggctgaca aaaacttttt ctgaagacaa aacaccaaaa tgttccaagg ccttgtggat
    37261 cccatcttgt tgattgctag tggtaatgtg cttggcagct tccttgacac tgctactacc
    37321 atttcccata gcgaccgaca taccgacgcc agccagcatt tcaaggtcat tatctgagtc
    37381 accaaaagcc atgacttggt tgaggtcaaa gccatattct ttcccaactc ggcgaatgcc
    37441 ttctaattta gaatttccct gattgatgac atccgatgca aaaggattgc tacgtgtcaa
    37501 tttcaagtct tcaaaatcag ctgccgcctt ctcagattct tctggtgtca tcagcatcaa
    37561 aacttggtaa ataggttgat tcatcaggtg aagcaggtcc tcttcctttt ggggaacaac
    37621 cttgctgacc atgcgattaa aagactgact caccgtccga gttaaaacag agggaacgaa
    37681 gcgactaatt cgttgggaaa aagaacccag accaaaggac atgattttag aacccaacat
    37741 ggcatccttg gtccctaagg caatctccgt gccctctttt ttagcatagc taattagatg
    37801 gcgcaaatgt aacttggaaa tagggctcgt gaacaagact ctgtctttac taaagatata
    37861 ctggccatta taggttaccg caaaatccag atccaaatcg tccatcaatt ccttaacaaa
    37921 aaaaggtcct cgccctgtcg ctacgccaac tagtacccct tgttctttga caatcttaat
    37981 cgcgtcctta gtggatttca aaacactctt gcgattgttg accaaggttc catcgatatc
    38041 aaaaaaaaca gctttgactt ccatcctatc ccaatctccc cttttgtgat acaatgatta
    38101 taccacattt cagaaagagt gagtaaatca tgcctaagaa aatccttgtt ttacatacgg
    38161 gtggaactat ttccatgcag gccgatgctt ctggcgctgt tgtgacgagt tcagataatc
    38221 ccatgaacca tgtgtccaac ccacttgaag gaatccaagt ccacgccttg gactttttta
    38281 accttccaag tccccatatc aaacccaaac atatgctggt cctctaccag aaaattaaag
    38341 aggaagcaga taactacgat ggagtggtga tcacacacgg aaccgatact ttagaggaaa
    38401 cagcctattt ccttgatacc atggaagttc cccatatgcc tatcgttcta acaggagcca
    38461 tgcgtagctc caatgagctc ggtagtgatg gtgtttataa ttacctaagt gctttacgag
    38521 tggccagcga tgacagggct gctgacaaag gagttttggt cgttatgaac gatgaaatcc
    38581 acgctgccaa gtatgtcacc aaaacacata cgactaatgt cagcaccttc cagactccaa
    38641 cacatggccc cctcggtctc atcatgaaac aggaaatcct ctacttcaaa acagctgaac
    38701 ctcgtgttcg ctttgacctt gatcacatac aaggtttagt ccctatcatc tcggcttatg
    38761 ctggtatgac agatgagctg attgatatgc tggatttaga acacttggac ggtttgatta
    38821 tccaagcctt cggagctggt aatattccca aagaaacggc tcaaaaatta gaaagccttc
    38881 tgcaaaaagg aattccagtc gctctggtat cacgatgctt taacggtatt gccgagcctg
    38941 tttatgccta ccagggtggg ggcgtacagt tgcaaaaagc aggcgttttc tttgttaaag
    39001 aactcaacgc ccaaaaagct cgcttgaaac tcctcatcgc cctcaatgcc ggactaacag
    39061 gacaggcttt gaaaaactat atggaaggct aatactcttc gaaaatctct gcaaaccacg
    39121 tcacgtcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
    39181 aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaaacagt gtgttgcgca
    39241 gcctttaacc agtcgcctag tccgctctat ggtattcatt aagtcaacat ctcttgttta
    39301 agagcacaaa atcaggaaat cttctcgatt ccctgatttt ttctatttac gttttcgtgt
    39361 tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca actcttcctt
    39421 atgcataatc ttggtcaaca tacgcatact aatggcacca agatcataaa gaggttgggc
    39481 aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac tagtaataat
    39541 ttcaaaatct tctggcacag aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc
    39601 caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa
    39661 ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac tataagtgat
    39721 tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat tgatgtcatc
    39781 cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt aactcactgc
    39841 atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct caacatcgac
    39901 agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt
    39961 caagtgataa cccatataga taatgccatc tacctgcttt gaaaagaggg tattgacaac
    40021 agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt acttgtacat
    40081 ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg taatatttgg
    40141 aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg
    40201 acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct cttttacatt
    40261 tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt cacgagcgac
    40321 atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt ctatctcaca
    40381 cattctttta caagtagagg tactgattga agctctatat ctacttacaa aagtgaagat
    40441 gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg taaacacttt
    40501 caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt tagctccttg
    40561 ctaccacctt agactaaaca caaaggagga aactaagccc tcctaaagtt atagtaaaat
    40621 gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    40681 agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt cactaccgtc
    40741 aattttagca catagccttc ataaaaatat tatatcatca taaccaacca gattcttttg
    40801 cgatattagc tgcctctgtt cgattaccag catccagttt tgaaagaata ttggtgacat
    40861 agtttcgaat agttccgttt gagaggtaaa gctgatctgc gatttcttgg ttggataagc
    40921 cccgggcgat tccctttaag acagcaatct cttgttctgt caacggattg ggacgggtca
    40981 tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg
    41041 tttgcatgag gtctgcaatg cttcgttcct ttaatacata agcatccact ccagccttga
    41101 ccgcacgttc aaaataccca gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa
    41161 gcctttctga tcgtatccac tccaagactt caagacctgt cttaacaggc atttctacgt
    41221 caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct tgcccattct
    41281 tggcttgaag gacagactcc acatctggtt gaagcgtgag caattgacac atggcatctc
    41341 gcaacatact ttgatcttct gcgactaata ctttcatctt agtttctctc cttataaggt
    41401 agtcgaactt gcacttccgt tggatgtttc tgactgatta cacttacttc tcctgaaaat
    41461 ggaaaaacac gatctcggac tgtatggagc tcatctcctt ttagaaaagc aaagccgcag
    41521 ccatcatcac ttactgttaa aatgagttcc ttctctgtcc gttctaattt taagtaagct
    41581 ttagacgctt tggcatgttt gatgatattg gtcaccaact caagcaaaat catagaagtc
    41641 attgcctcca attcttgagt aaggctagca gtatctagtt ggttatccgt ttccacctca
    41701 attccagcaa tttctaacat ctttttcaca gtctctagtt cggatgtcaa agttctagac
    41761 ttaagatttt ccacaatggt tcgaacttca cgcatcgatt ctttgctaat ttgctgtatt
    41821 tctcttaatt ccttttccac ttgtggataa gcctgcattt gaaatagctg caaggctaga
    41881 tctgtcttga cactaagcat agcaaaggta tgtcccagac tatcatgcaa atcctgaccg
    41941 atacgattgc gctcattttc tgctagcaat agatttatct gggtattttg ctcgacctga
    42001 gcttctttca aatcctcgac aaggcgaatt cgaaccgagc ccaaagtcat caaatcgaca
    42061 aaagtaagaa ttacaagcat atagactaga aactcaactt cgattctctg aaaaatcaaa
    42121 agtcgcccca caacaaggac ttgagcaagg agaaatgtcc atacatgtaa agactttaaa
    42181 ctacgtacgc caaaatgata aattaagaga ttggaaagga aaaagaaaaa ccagatataa
    42241 ttcccagcaa caaaggcggt attcccagct acatagacca gcatgatccc ccagaaaagc
    42301 caagataggc gctggttctt agttattaaa acacccaaat acgtcactac aaatagaata
    42361 tcaaccaata aatgccaagc aggaagctcc ccaatcacta caggtaggat gggaaaaagc
    42421 ataaaaatca aactgaccca aaacatatag tgtatgcttt tcagtctttc aagcattaag
    42481 cattctcctt atgaccttga aggtaaatag tcaaaccaaa taaaactgct gaaaaaacaa
    42541 gtaaataaac tgtggctgat agattgatgc caccctcgtt taagaaggtc ttgagcaact
    42601 ccatcaattg ataggtcggg agacacttac caactgcttg catccagtct ggaaataaag
    42661 aaatgggcat ccagagtccg cctaaaacag ccaatcctag ataaagaaga ttgcccacaa
    42721 cagacatcag ctgactagtt ggtaagagag tcaaggtcaa gccaagtgct acaaaagcaa
    42781 tactccccac aatcagcaaa atcgcagctc caacccattt tactagaggc atgtctacac
    42841 ctcttacaaa atgtccaact gtaaaaacaa ccagaattga gaccaaataa tcaaccagca
    42901 tacttgttat ctttgataga taatattcta ccatatttac agggctatga cgcaatgttt
    42961 tctgccagtt gttcatctta tcggtatgta aaacagctgg aaatgagagg atagttgtcg
    43021 acatcatgga aaaggcagtc atggagatga ggtaatcacg cataaaattc gcgggttcac
    43081 ctggtgtgtc ctgatagata ccagaaaaaa ataaatagaa agccgtcggc atccctaccg
    43141 acaatagata atagattaat tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta
    43201 tccatcgttt catcttagtt atctcccttc tgcgtctctt caaagattgt attcaacaaa
    43261 ctacgattat taacttcgat ttcttgcatc ctacatcctg cttgggctaa tagttcccag
    43321 aaagcatctg cttctcgagt gactacttgt aaagaatctt gctttagggt ccagttttca
    43381 accaaatttg actgctctac gacttccttg taagctatag gaaggataaa gtgcttttct
    43441 atttcctcgc tacgcatagc tagaggcgtc gtatctcgaa tcaactctcc cttatttaag
    43501 agcaaaatgc ggtctgcagt gtgttccact tcctcaatat aatgggacga atagagaatg
    43561 gtgactcctt gcgcttttaa ctcctggaca atttcccaaa aacgttgacg agttgaggta
    43621 tccatggacg cagtaggctc atctaaaaaa acaatctttg gtcgcccaat taaggtcaag
    43681 atgaaagaaa agagacgctt ttgaccgcct gataattttt ctgccaactg ttctttttgt
    43741 tgcttgacaa actgcaatag ttgatcaatt tcctgattgc tcaaaggatt tggatagata
    43801 cgttgaaaga aagcaatcaa ctctttaact tttaatttct gaacgattac attttcttga
    43861 gggaggtaag ccctagtata gtctaactta gaactcgtca ctggtaaacc ttgaatagat
    43921 acttgaccgc ttgtgaccag tttatctcca agcaaacaat ctaagagtgt tgtctttccg
    43981 gcaccatttg gaccaattaa ggcaacacat tcaccatcgt tgatttcaaa ggagatgttc
    44041 cgcaaaattt ccttgtcttt tattttctta ctcaatttct caactttaac caccgtcatg
    44101 agactctcct ttcaaccact ccattcccat agggaaaacg acgaaaatca taaatccaaa
    44161 ccccaaagca ccatgaatga attggcgaag caaggcttga tcaaaccaat cagtaaacat
    44221 ttccactaac cataccaaga gtgacaggcc gataaagaaa tagatgatcc ctctcttcat
    44281 tcctcaaact cctttttcac atctctgact aatttcaaac cttctctaac aagccaagac
    44341 atgattccaa agccagcaaa gaccttccaa ggaaaatggt agaaatcctc atccaatccc
    44401 gaaaacatga gataggtcat aactcctgct actactaaac tcattgcaat aatcatttta
    44461 tttctcatct cttcttcccc catttcatac tacaattata gtcttttaaa atcagaggag
    44521 gcagaagctt ctgtcactag aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa
    44581 gcaagataca ctatacaata aaacacaatc agaaaaatct aaggcaactt cctcaaaaga
    44641 gatatcaaac tcaattcaca ccataatgta aactaatact tatttaaaat caaaaagagt
    44701 agaaattttt atcagacaaa cacatatata gtgtattgaa tctataacag taggccttaa
    44761 atactaaaat atttctataa attaatttaa ctttcctgat agaactgttc atatcttatt
    44821 tcaattctct atattatacg ttgaacaaaa cccttctatt gctttcttaa aaatttataa
    44881 gagttataaa atctgttaaa tttcaatgtg tatacctaaa ctacggtatt tattgaaaag
    44941 actggggaca aaaagtatac gctgccaaaa tgaattactg aaaatcaaaa aagagaggac
    45001 caaactgatt ccctcttaat gtatataata tctagtttta aaaatacaca ctcacatatc
    45061 tctgt
//
LOCUS       DAVLHM010000014        44157 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLHM010000014 DAVLHM010000000
VERSION     DAVLHM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.014"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1202)
                     /locus_tag="VXE45_000782"
     CDS             complement(<1..1202)
                     /locus_tag="VXE45_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0788853.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFLRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWFDGDQNTNVSESNNLMNYLEN
                     GVVISDKIP"
     gene            complement(1253..1417)
                     /locus_tag="VXE45_000783"
     CDS             complement(1253..1417)
                     /locus_tag="VXE45_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0788854.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(1498..4149)
                     /locus_tag="VXE45_000784"
     CDS             complement(1498..4149)
                     /locus_tag="VXE45_000784"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0788855.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVIAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4142..4720)
                     /locus_tag="VXE45_000785"
     CDS             complement(4142..4720)
                     /locus_tag="VXE45_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0788856.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAEILQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(4720..5280)
                     /locus_tag="VXE45_000786"
     CDS             complement(4720..5280)
                     /locus_tag="VXE45_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788857.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHIFPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLDFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(5267..5715)
                     /locus_tag="VXE45_000787"
                     /pseudo
     CDS             complement(5267..5715)
                     /locus_tag="VXE45_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            complement(6127..6522)
                     /locus_tag="VXE45_000788"
     CDS             complement(6127..6522)
                     /locus_tag="VXE45_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0788858.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQPAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(6618..6872)
                     /locus_tag="VXE45_000789"
     CDS             complement(6618..6872)
                     /locus_tag="VXE45_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0788859.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(6882..8216)
                     /locus_tag="VXE45_000790"
     CDS             complement(6882..8216)
                     /locus_tag="VXE45_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0788860.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8216..8449)
                     /locus_tag="VXE45_000791"
     CDS             complement(8216..8449)
                     /locus_tag="VXE45_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0788861.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            8480..8557
                     /locus_tag="VXE45_000792"
                     /pseudo
     CDS             8480..8557
                     /locus_tag="VXE45_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8898..9080)
                     /locus_tag="VXE45_000793"
     CDS             complement(8898..9080)
                     /locus_tag="VXE45_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788862.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9082..9861)
                     /locus_tag="VXE45_000794"
     CDS             complement(9082..9861)
                     /locus_tag="VXE45_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788863.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(10141..10491)
                     /gene="rbfA"
                     /locus_tag="VXE45_000795"
     CDS             complement(10141..10491)
                     /gene="rbfA"
                     /locus_tag="VXE45_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0788864.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(10742..13534)
                     /gene="infB"
                     /locus_tag="VXE45_000796"
     CDS             complement(10742..13534)
                     /gene="infB"
                     /locus_tag="VXE45_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0788865.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(13551..13850)
                     /locus_tag="VXE45_000797"
     CDS             complement(13551..13850)
                     /locus_tag="VXE45_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0788866.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(13843..14136)
                     /locus_tag="VXE45_000798"
     CDS             complement(13843..14136)
                     /locus_tag="VXE45_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0788867.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(14158..15294)
                     /gene="nusA"
                     /locus_tag="VXE45_000799"
     CDS             complement(14158..15294)
                     /gene="nusA"
                     /locus_tag="VXE45_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0788868.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(15338..15817)
                     /gene="rimP"
                     /locus_tag="VXE45_000800"
     CDS             complement(15338..15817)
                     /gene="rimP"
                     /locus_tag="VXE45_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0788869.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMGKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(15943..16578)
                     /gene="trmB"
                     /locus_tag="VXE45_000801"
     CDS             complement(15943..16578)
                     /gene="trmB"
                     /locus_tag="VXE45_000801"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0788870.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQDPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(16575..17369)
                     /locus_tag="VXE45_000802"
     CDS             complement(16575..17369)
                     /locus_tag="VXE45_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0788871.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(17530..18141)
                     /locus_tag="VXE45_000803"
     CDS             complement(17530..18141)
                     /locus_tag="VXE45_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0788872.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(18292..18525)
                     /locus_tag="VXE45_000804"
     CDS             complement(18292..18525)
                     /locus_tag="VXE45_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788873.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(18567..19256)
                     /locus_tag="VXE45_000805"
     CDS             complement(18567..19256)
                     /locus_tag="VXE45_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0788874.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(19308..19691)
                     /locus_tag="VXE45_000806"
     CDS             complement(19308..19691)
                     /locus_tag="VXE45_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0788875.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(20320..20691)
                     /locus_tag="VXE45_000807"
     CDS             complement(20320..20691)
                     /locus_tag="VXE45_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788876.1"
                     /translation="MIKKNHILCEIVPGAVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            complement(21160..21279)
                     /locus_tag="VXE45_000808"
     CDS             complement(21160..21279)
                     /locus_tag="VXE45_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0788877.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(21383..21532)
                     /gene="blpO"
                     /locus_tag="VXE45_000809"
     CDS             complement(21383..21532)
                     /gene="blpO"
                     /locus_tag="VXE45_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0788878.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(21776..21979)
                     /gene="blpN"
                     /locus_tag="VXE45_000810"
     CDS             complement(21776..21979)
                     /gene="blpN"
                     /locus_tag="VXE45_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0788879.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(21995..22249)
                     /gene="blpM"
                     /locus_tag="VXE45_000811"
     CDS             complement(21995..22249)
                     /gene="blpM"
                     /locus_tag="VXE45_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0788880.1"
                     /translation="MNTKMMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            22529..24654
                     /gene="blpA"
                     /locus_tag="VXE45_000812"
                     /pseudo
     CDS             22529..24654
                     /gene="blpA"
                     /locus_tag="VXE45_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            24665..26026
                     /locus_tag="VXE45_000813"
     CDS             24665..26026
                     /locus_tag="VXE45_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0788881.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGIFKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            26083..26238
                     /gene="blpC"
                     /locus_tag="VXE45_000814"
     CDS             26083..26238
                     /gene="blpC"
                     /locus_tag="VXE45_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0788882.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(26282..27622)
                     /locus_tag="VXE45_000815"
     CDS             complement(26282..27622)
                     /locus_tag="VXE45_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0788883.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(27636..28373)
                     /locus_tag="VXE45_000816"
     CDS             complement(27636..28373)
                     /locus_tag="VXE45_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0788884.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(28378..28716)
                     /locus_tag="VXE45_000817"
     CDS             complement(28378..28716)
                     /locus_tag="VXE45_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0788885.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            28992..29321
                     /locus_tag="VXE45_000818"
     CDS             28992..29321
                     /locus_tag="VXE45_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0788886.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(29489..30538)
                     /locus_tag="VXE45_000819"
     CDS             complement(29489..30538)
                     /locus_tag="VXE45_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788887.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(30535..31266)
                     /locus_tag="VXE45_000820"
     CDS             complement(30535..31266)
                     /locus_tag="VXE45_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788888.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            31334..31744
                     /locus_tag="VXE45_000821"
     CDS             31334..31744
                     /locus_tag="VXE45_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0788889.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            31754..32041
                     /locus_tag="VXE45_000822"
     CDS             31754..32041
                     /locus_tag="VXE45_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788890.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            32203..32442
                     /locus_tag="VXE45_000823"
     CDS             32203..32442
                     /locus_tag="VXE45_000823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788891.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(32764..33900)
                     /gene="dnaJ"
                     /locus_tag="VXE45_000824"
     CDS             complement(32764..33900)
                     /gene="dnaJ"
                     /locus_tag="VXE45_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0788892.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(34105..34359)
                     /locus_tag="VXE45_000825"
     CDS             complement(34105..34359)
                     /locus_tag="VXE45_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788893.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(34472..36295)
                     /gene="dnaK"
                     /locus_tag="VXE45_000826"
     CDS             complement(34472..36295)
                     /gene="dnaK"
                     /locus_tag="VXE45_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0788894.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(36775..37299)
                     /gene="grpE"
                     /locus_tag="VXE45_000827"
     CDS             complement(36775..37299)
                     /gene="grpE"
                     /locus_tag="VXE45_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0788895.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(37326..38360)
                     /gene="hrcA"
                     /locus_tag="VXE45_000828"
     CDS             complement(37326..38360)
                     /gene="hrcA"
                     /locus_tag="VXE45_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0788896.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(38524..38961)
                     /locus_tag="VXE45_000829"
     CDS             complement(38524..38961)
                     /locus_tag="VXE45_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0788897.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            39641..41974
                     /locus_tag="VXE45_000830"
     CDS             39641..41974
                     /locus_tag="VXE45_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0788898.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            41987..43450
                     /locus_tag="VXE45_000831"
     CDS             41987..43450
                     /locus_tag="VXE45_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0788899.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFKDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            43450..>44157
                     /locus_tag="VXE45_000832"
     CDS             43450..>44157
                     /locus_tag="VXE45_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0788900.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRI"
BASE COUNT        13519 a         9395 c         7993 g        13250 t
ORIGIN      
        1 ggaattttat ctgatataac aacaccattt tcaagatagt tcattaaatt atttgattca
       61 ctaacattag tgttttgatc tccatcaaac caaaaataat ggttatcgga atctaaatac
      121 gatgagttta aaatattatt acaaattatt tgatttgctc caccaggaat atatctcact
      181 actaaattct gtttaagatt ctcactacct gaatgagtga taacaaactc tagaatatat
      241 ttagctagtc tatcttcaac ataaatcatc ttcctagaat gatacacatc acctaattca
      301 aaaaatgcat cctgataatc aatattttca ataacatcta ccttttctcc gtttttcact
      361 aaaagtttca cggcttctct aagaaaatct tttataagtt gtgtagaatg tgtagtgata
      421 ataatttgat gttttttatt taaacactct tgaagtaaaa actctttaaa tttatagatt
      481 gcactcggat gaagtgagat ttcaggttca tctattaata ttaatgaatt tgattgcgca
      541 tttactatat catttactaa caaaataatt ctagcctcac ctgttcctgc aaaagcctcg
      601 gaatattctt ttccagattt tttcatccaa atagttttgg aagcttttat atcatcacct
      661 tttgaataca acttatgtgt taaaatttga atgtctgtat aagattcatc cattatttca
      721 ctaataattt cacaaacttt atcatcaact ttaacattat ctataaccat ttccttttta
      781 taacgcgtat aactacttgt attattcttt aaaatatcag caactggttt agatcgtaat
      841 cttataaaat cttgtttact acgttgagta gaaatttttt taaaattata gtgatagaaa
      901 aataaatcaa aagcagaaac atattcttta caatcacaaa agacaacatt tttttcaatg
      961 ccatcccatc tgtctgtcga agaacttcca atatatttat ttttgggtaa tctttccatc
     1021 tcatattgtt tttgaggagc atatggttcc caataatcta atcctttttt tgttccagaa
     1081 cggcctttaa gaacttctac atttctagaa gctttaacgt tataatatga atagattaaa
     1141 cattgtttcc catccacttc atctatttga tcaacatttg tactaaacca atattcagac
     1201 acacttttat tggctggaga accatataaa gcttgtaaaa ttgaagtttt atttactcca
     1261 tatctattac agacacctca ggattattta acttataagt tttaacagct acggaatcaa
     1321 tttcaacagc aacttgaaca tctatgcctg attttttaag gccacttgta gtgccacctg
     1381 caccgttaaa taaatcaata gcaacaattt tccccatagt attctcctaa agtttctcct
     1441 ttttattata acattatcaa atgtaaaacc caacccgata gggttaggtt tttaacatca
     1501 tttcaccaac ttcttcatct catcaatacg tgctacggtc gcatcatact tggcttggta
     1561 gtcggcttgt ttgtcttttt ctttttggac aacttctggt ttagcgttgg cgacgaagcg
     1621 ttcgttgctg agttttttgc caaccatgtc gagttctttc tgccatttgg caagttcttt
     1681 ttccagacgt gccaattctt cttcgacatt caagaggtct accagtggca agaagatttc
     1741 ggctcctgta ataacgcttg acatagccag ttcaggtgca gggatggttg atgcgatttc
     1801 caagtgttct ggatttgtaa agcgtttgat atagttgaca ttgctgttaa agaaggcttc
     1861 caagtcgcta tcgcttgtct taacaaggat ggtgataggt ttgcttggtg ctacatttac
     1921 ttccgcacgc gcattacgaa cggcacggat caagtctttg agactttcca caccagtgtg
     1981 ggcagcaagg tcctcaaagg ctgggttgac agttgggtat gctgctgtca cgatagagcc
     2041 ttcagcgtac tgaccaaaga tttcttctgt cacgaacggc attattgagt gaaggagacg
     2101 aaggatttta tccagcgtat agaggagaac agatcgagta attaccttat cgtcttcatt
     2161 gtcgctgtaa agaacttcct tggtcaactc aacataccag ttggcaaatt cttcccaaat
     2221 gaagttgtaa aggatatgac cagccacacc aaactcgaac ttatcaaagt tttcagtaac
     2281 ttttgcaatg gtttcgttga gattgtggag aatccagcgg tccgtcacat taccagcctc
     2341 acctgttgca acttttgtga cattgtcatg cgccacatcc agcgtcaaac ctccattgtt
     2401 catgaggata tagcgagaaa tgttccaaat cttgttaata aagttccatg aagcatccat
     2461 tttctcataa gagaaacgca cgtcttgtcc tggcgcagaa ccgtttgaaa ggaaccatcg
     2521 aagggcatcg gcaccgtatt tctcgataac atccattggg tcaatcccgt taccgagaga
     2581 cttagacatc ttgcgtcctt gctcgtcacg aatgagaccg tggataagga cgttttggaa
     2641 tggttgacgg cctgtgaatt ccaatgactg gaagatcata cgagacaccc agaagaagat
     2701 gatgtcgtaa cctgttacca aggttgaagt tgggaaataa cgtttaaagt cttctgagtc
     2761 gacttcaggc cagcccatgg ttgaaaatgg ccagagggca gaactgaacc aagtatccaa
     2821 gacgtcttcg tcctgagtcc atccgtcacc ttctggagct tcttcgccga catacatttc
     2881 accatcagca ttgtaccagg cagggatttg gtgaccccac caaagctgac gagagataac
     2941 ccagtcgtgg acattttcca tccattgaag gaaggtatcg ttgaaacgag gtgggtagaa
     3001 ttcgaccttg tcctctgtgt cttggttggc aatggcgttc ttagccaatt ggtccatctt
     3061 gacgaaccat tgagtagaca agcgtggctc aactacgaca cctgtacgtt ctgagtgacc
     3121 aacactgtgg acacgttttt cgattttgac aagggcaccg atttcttcca acttagcaat
     3181 gactgcctta cgagcttcaa aacgatccat gcctgaaaat tcaaaggcaa gctcattcat
     3241 agttccgtcg tcgttcatga cgttgacttg tggcaagtta tgacgttggc caaccaagaa
     3301 gtcatttgga tcgtgggcag gtgtgatttt cacgacacca gtaccaaact caggatctgc
     3361 gtgctcatct ccaacgattg ggatgagttt attagcgatt ggaaggatga cgtttttacc
     3421 aatcaagtcc ttgtagcgcg ggtcttctgg attaaccgca accgcaacgt ccccaaacat
     3481 agtctcagga cgagttgtag caacttcaag ggcgcgtgaa ccatcttcca gcatgtaatt
     3541 catgtggtag aaggcacctt ccacatcctt gtgaatcacc tcaatatcag aaagggctgt
     3601 gcgagctgct gggtcccagt tgatgataaa ctcaccacgg tagatccagc ctttcttgta
     3661 aaggtccaca aagaccttac gaacagcttt tgacaaacct tcgtcaagag tgaaacgctc
     3721 acgagaatag tctacagaga gccccatctt gccccattgt tccttgatgg tagtggcata
     3781 ttcgtctttc cattcccaga ctttcgtcaa gaaagactca cgaccaaggt catagcggga
     3841 aatgccctca ccacgcaagc gctcctcaac cttagcctga gtcgcaatac cagcgtggtc
     3901 cattcctgga agccaaagcg tatcaaaacc ttgcatgcgt ttttgacgga tgataatatc
     3961 ttgcaaagtt gtatcccaag cgtgaccaag gtgaagttta cctgtaacgt ttggtggtgg
     4021 aataacgatt gaataaggct tagccttttg atcgcctgaa ggcttgaaaa catcagcatc
     4081 aagccatttt tggtaacgac cagcctcaac ctcggctgga ttgtatttag atgaaagttc
     4141 tttagacatg tgtgtgtcct ttctctattt tgtttatttt attttgaatt tgcttagcag
     4201 cttcttctgc agacaaattc gtattattta ttttaaagta gtggtgcaac tcattcggtt
     4261 gatattggga atttaattga agtatttcag cggtctctat aatttctctt tcagatacct
     4321 caatatgtcg ttttaagggt ttgtacttta atcgattctc cgttcgattt cgacgtatgc
     4381 actcttcaag acttgtttcc aactcaacaa aaagaatctc ttgatgataa tcatccaaca
     4441 aactctgaat ttgctttaaa tatatcagat gatactgatt tgaaaaatca attacatctg
     4501 ttaaaattac tgatcgctga tttcttgcac tcgctccaag gaatgaaaaa gtgattccac
     4561 gaacaaattc ccacatttcc tctgtatagt cctgatagat ttctagtgca aaatcgatgg
     4621 cttgatggtt ataaaatagg gtagcatccg tcagtcgaga taattcttga ccaatggtca
     4681 tttttcctga tgctggagca ccaatgatga aaagatgcat caaatcacct cccattcact
     4741 cttcagcaag gcatatctta aatcatcaca gcagttgcct tgagcatctt tgcggtctct
     4801 tatgcgagct tcgagggtaa agtcaagctt ttccgcgact cgtttacttt gaaggttata
     4861 tccaaagcaa gttagttcaa tcttgtgaag acccaaatct ttaaaggcta agtcaatcaa
     4921 ggcacgcgca gcttctggca cataacctcg cccccaatag tctgggtgta aggtatagcc
     4981 gatttccagc acatcatctt catggcgatg gttgaaatcg acagagccaa cgatcttatc
     5041 cgttcctttg acgacaatcc cgtagcctgc tgggagattt tccttttgat tacgctccgg
     5101 aaaaatgtgc tccagataat aaatctcatc ttccaaggtc ttgactggag gaaaacctgc
     5161 tggataggcg acctctggca aactagcata gtcaaagata tcctcagcat ccgccacagt
     5221 acggactcgt aaaacgagac gttctgtttc gattttatct ggcagctcag ttcttgccat
     5281 ccttcttcct cgcttttttg atgaaactgc ccttcatatc tacacgcttg tccagatagc
     5341 aataaacgcg ctgatatcca tctcccatga aataggttgg gcaaacagtt gatttttaaa
     5401 atgtcccttt tcatccagga gttctggggc aacaagtcgc tcaagaatct tggcaaagat
     5461 gtggcaaata ccgtattcct caacaatcct atctacccga taatctaaaa caagtggaca
     5521 ggcgtctaaa ataggagtct gagttcgttc agaaatttca taatgcactc ccaaacgttc
     5581 caatttctcc tgatgactga taaaaccagc ctgctccatc gcaagcatag aagtttcatc
     5641 agaaatattc acagtaaatt tttgatattg tttgatctgc tctgcggcat tctctctcgc
     5701 aacgactcca atcacaaccc aatctcctag actataagag gaactacagg tcatgatgtt
     5761 atagctaaaa ttctgatctt gatatcctaa aataaaaaca ggaaaaccat aatatagttt
     5821 attagtttta aatgattgtt ttataacaac ctcctttgac taagacacaa aagaaaagcc
     5881 ctgccatcta catgacaggg acgaatgtgt ttatccgcgg taccacccaa tttcgggcca
     5941 agcccgcatc tttagtcttt aaaataaaaa gacagaaata tttcattttt tcagtcatta
     6001 gcaaccagtt ttgacacatt tgtggacttc tcagcgccgc cactttctgt aaaatgtggg
     6061 attcaaaaca cctctaatgg ctctattgta gcaagttttt ctcggaaatg caaggctcaa
     6121 gaaaaattac ttgaacttga tgccattttc tttcaatttc ttgatggtag ctgggccgat
     6181 tcctttcaag gcaaggagtt ctttttcagt ccagtttttg aaatctgaag cagacttgat
     6241 tccttcatca tagaaagtct tggcacgatc aagtggaagt ccccccaagt ttgctgcaaa
     6301 atcttctaca gaattagcta ctttttgagc ttgctctttg gtagcttcta ctgcttgttc
     6361 aactttttta gaaacagcct taccagctgc gcttgctggc tgttctgcac gcttcacgac
     6421 tttttttgtc tcatctacaa ccttagtcac agtacttgaa aaggcacctg cgcgacggag
     6481 gccatttcgt aattgttttt tacgattgag tttctttgac atgataaaat cctttcaata
     6541 aaaaatccct gctctgacaa ggatttaaca taaacattct atcaagattt tagtgaaaaa
     6601 tcaagaatct ttctcgttta ataatttcgc tcaccaaaca agccttctgg caaatcatgg
     6661 aatcccttgc ctgctttgaa gttttcaaac ttaccaagca agaactgata agcatccaag
     6721 cgactctcgt agcgaatcat ggcatctttg gcacgctcgt cctggtcttc ttcgtaaact
     6781 ttttgacttt ccttgtgcgc catgtcgtta atcatgattt gggtattgac ccaagcttca
     6841 aattccttca taaattcttg ttcgtaactc attttttctc cttattctaa tccacgaaaa
     6901 tagtccgtat caatctcacg gtagggctgg atatcctgaa catactccaa cactccttgg
     6961 aattctccgt cttcatcgtg tactgcagca taggtgatgt ggacaaactt acctcgcgac
     7021 tcagacttga accacatttc atacttgtct ttgcttccct cacgaagccc cttcatgata
     7081 gttttgacct tgtccaagta cttaggcgga tggcagagtt cgacattgcg cccgacttga
     7141 gacggcgtcc gtttgaaaat catctcatca gctggcgtat tgtcattgta atactggaaa
     7201 atatcatctt tattgacaaa ggtaatctcc atagggaggt gattgaggat gagattggcc
     7261 tgctcgactg aaagatagcc attaccaaaa gcctgttgac tatggcggtc cagcacagct
     7321 tccttttcct taggggtaaa ggtaatggta aaatggcctt ctggcgtatc tatgacttgt
     7381 tgaacttgac cttctgccgt atctagctgt acaggctcct ctgcaatctt ttcctcaata
     7441 aagctctgtc gttctggcac ccatttctct gacggacgga tgatggcata gccataggca
     7501 tcgctctcct ccgcaatctg aagccagtca tcctgagtaa aagactcaag gagaatcatg
     7561 aggaggatgg actcttcctt gaaaatcata ctttcaaact ctgtcgcaaa agcttcaaaa
     7621 gcttccttta cactgctaat tgacacttct ggtagtgact tggctgtcgt tagagctgtt
     7681 tgaaagagtt ccctaatctg atcatccact ccccacataa ctttgggagg tgaatcgtgt
     7741 ccatagcgct ccatgatagg aaagaagagt tcttccttac gttggtaatg gatgtcaaat
     7801 tgacccacaa gtcccatctg acgcaccaaa cccttacgca tctccgccag catttcctcg
     7861 tcttccatat actcataggt atctaacaat ctacgaatgc gaatcaaggc cgcacggaga
     7921 gccagatttt cttctttgaa gacacgaact gggtgacctg gatgctcagt atctgaaact
     7981 tcgacacctt tgatagcatt tttaaaaaga ttggcatgga catcacagag ttccataaca
     8041 tcttcaaagg tgacacctga gtctgagttc atcagctcgt gctccataag ggaaatctcg
     8101 atggctgaga cacccgcaaa ggtcgcatca aagcgctctt gaaccgactc aggagaggcg
     8161 ccattgtgca attctaacaa aatatcccgt aggacatgaa tccgttcatc tgccattagt
     8221 ctaatccaat cacttcgtag ccattcgctt ccagtgtgcg tacaatcttg tccataggag
     8281 ttcctgctag cttagaaccc tgtttgagcg ataccttgcg accaactgta ttgcgcatta
     8341 agggattggc aaggggttta aaacccaact ccactagaat ttccaagact tctggatgct
     8401 tgtccaccac ttctgcaaca ggaattgaca catcgatgat attgtccatg acgacctcca
     8461 ttgtatgttc taatactcaa tgaaaatcaa agagcaaact aggaagctag ctgcagactg
     8521 ctcaaaacag tgctttgagg ttgtggatag aactgacgaa gtcagctcaa aacaccgttt
     8581 tgaggttgta gatagaactg acgaagtcag taaccatacc tacagcaagg tgaagctgac
     8641 gtggtttgaa gagattttcg aagagtataa aatgatttta ctgcttatat tataccatat
     8701 ggagagagat taaaaaacta gcagtggggt tcctgctagt tttctgcgac ttggattacc
     8761 atctagataa gtttaaagaa ccaatccaat atcttgtaaa acagcaattg aactgcaaaa
     8821 gaaatgatca tccaaaagaa tttcacaatc ccaataatcg gtttgataaa aagaatagca
     8881 agaagaccaa aaaaatttca ttctctctcc tctggcttaa tgagccaccg agccgtatcc
     8941 attagcttat ctgcaataaa aagtttgccc agaccaacaa cgacatggtc agctttcttt
     9001 atcgttttca tcacttttac accttgcacg gtcaaaaagt aattaccata aattttagct
     9061 agagttttta tgagtcccat attactctcc ttcgatgatt tcagcctctt ttcggattgt
     9121 ttcaacatct tcttgatatt gaacttcact atagttaact agcttggaca attctttctg
     9181 caagctttca cccatcggtt tcatagttgc aaaggttaaa ccacctgaaa tgataccacc
     9241 caagatagga ataaatttcc ccattccttt ggccagccct cccttggtaa gattcacacc
     9301 aaatattctt aagacttttt tcaaaatagg ataccaaagc gtcttagtta aagctttatt
     9361 aggtactgtt ttcattacct gtttggcaat tgttatacca ccagcacgta gcaaagcagc
     9421 agttccattc acccccaaca tgacgcctag ataaagcaag agggtatttt gagcatcttc
     9481 actcaactca tcgcgtgaag cccaaagatc ctcataacca taaatataac ctaattcttg
     9541 ggccaatttc agagagaaag cataaaattg agccacatca gctggaatgg taattgccat
     9601 agcaagccct ccaggtaatc ctgccaaaac agaagtccca ctcgctaata aaacattatc
     9661 cctaatacag gcattagcca ctcgatctaa gatttcttga gataagagag acgttggacc
     9721 ttgttccaat aaggtaggaa tgtcctgtgg acccaattct ttggaaaact tatccactaa
     9781 aaatttcgaa cgatcaacct taacaactgg tagttttacc acttgttgta atacttgcat
     9841 agctaagtct tgttcagcca tatacaaact ccttatttct tttttacacc ttatcatatt
     9901 atatttccta caaaaaaagc attttctaat tagataacat taaaaaatac agaacccctt
     9961 tttttatagt aaaatgaaac acgaacagga caaatcgatc aggacagtca aatcgatttc
    10021 taacaatgtt ttagaagtag aggcgtacta ttctagtttc aatatatttt aaaagaatat
    10081 ttttccattt caaattcaac ctattttcct ccaccaaaaa agaggggcaa cccctcttct
    10141 ttagttctta tccagattgc gtagcatctc gtcaatcttg tttccatact cgatggactc
    10201 gtctttgacg aaggtcaaat ctgggatttt gtacaatttc aaattgcgac caagttcacg
    10261 tttgatggta ccagttgctt tttcaagccc gatttgggct ttttggttat ccgaagcaag
    10321 gttactcaaa atggtgtaat aaaccttggc aacagacaag tcacccagca tctgaacatc
    10381 tgtgatggtc acaccttgga cacgtggatc acggactttc ttttgcaaaa tctcattgac
    10441 ttcacgcttg atttccatgc ccacacgatc tgtacggaaa tgatttgcca tgatattcct
    10501 ttctctactt tgaaccaaaa gctaggccag cagacctagc tattttaaac ttcttgattt
    10561 tcagtttaaa ttgaaacgaa gttcaatttg aagtcatctg cttctttcgc cgtggtgaaa
    10621 gtgatggaac tgatttatca gtcccatcac aggggatttt tgagacccta ggctcaaaaa
    10681 taagcaatga aaccatcggt ttgcttgcgt ccctcaccac ctaagaaagg agcaaaaaat
    10741 cttatctctt gatttcttcc atgacatacg cctcaatcac atcatccatc ttaatatcat
    10801 tgtagccgtc gatcatcaat ccaccttcac ggccgtttgt aacttcctta acgtcgtctt
    10861 tatagtgttt caagcttgcg agttcaccat catagataac gacaccatca cggataacac
    10921 ggactttaga gtcacgggca accttaccgt tgataaccat aaatccaccg atagttccca
    10981 ctttagacac cttgaaggtt tcacggataa ctgcttcacc aataactttt tcttcaaatt
    11041 ctggatcaag catccctttc atagcttctt ccatctcttc gataaccttg tagataatgc
    11101 tgtgaagacg gatttccaca tcgtcagctt ctgcttgttg acgagcttgt ggtgtagggc
    11161 gtacgttgaa accaacgata aaggcatttg aagcttcggc aagggtcacg tctgattcgt
    11221 tgatagcacc gaccgctgag tggacgatag tcactttgac accttccacg tcaatctttt
    11281 gaagtgaggc agaaagggct tcaacagaac cttgtacatc agccttgatg ataacattaa
    11341 cagatttgag ttccccagct ttaagggtat caaagaggtt ttcaaggcta acacgttggg
    11401 tagcttgacg ttgtttcatg agggcacgtt tggcacgctc ttcacctgct gcacgcgcag
    11461 atttttcatc ctcgtaaacg gcaaagtggt cacccgccat cggtgcttcg ttcaaacctg
    11521 tgatagagac tggtgttgat ggtccagcaa ctttaacacg acgaccaagg tcgttggtca
    11581 tagcacggac acgaccgaag gtatttccga caacgattgg gtcttgaaca ttcaaggtac
    11641 cttgttgtac aagaagggtt gcgaccgcac cttttccttt atccaagcgc gcttcgataa
    11701 ccgtaccgat tgcacgcact gttgggtctg ccttgagttc ttggatttca gctacaagaa
    11761 ggactgtttc caacaattct tcgatatttt ggttgaattt agctgagatt tcaacaaatt
    11821 cagaatctcc accccaagca gttgacataa ctccatgctc tgccaattca ccgataacgc
    11881 gttctgggtt agcacctggt ttatcaatct tgttaatggc tacgatgatt ggaacgttgg
    11941 ccgcttttga gtggttaatg gcttcgatag tctgaggcat aaccccgtca tctgccgcta
    12001 cgaccaagat cgtaatatcg gtaacagaag caccacgcgc acgcattgat gtaaaggccg
    12061 cgtgtcctgg tgtatcaagg aaggtaatct tcttaccatt ttccacgatt tggtaggcac
    12121 cgatatgctg agtaatacca cctgcttcac ctgtcgcaac acgtgagtta cgaagagtat
    12181 ccaaaagggt tgttttaccg tggtcaacgt gtcccatgat agtaacaact ggtggacgct
    12241 caaccaattc atcttcattg agataaccat cttcgacaaa gaaacgttcg atgtcagcat
    12301 tatccacttc aaccttttgt ttggcttcga taccgtaatc caccatgagg agttcaattg
    12361 tttccccatc caaggattgg ttttgtgtgg ccatgacacc catcatgaaa agtttcttaa
    12421 caatttcagc tggttcacgt ttgatacgtt ttgcgatttc cgcaacggtc ataccatctg
    12481 tatattcaaa ttctgttggc aattcatgga atttacgctc cgtaacaggt tttggagtct
    12541 gattacggtt gttcttgtta ttgccttttt tgttcttttt gttgttattc cagttactat
    12601 tcttttgatt tctcacttga ttttgactac ttcgattctt ttgttgtttt ctaggaccat
    12661 cttcttcatg atcataatcg tcacgatttt tgtctggtcg agcttgtttt ttacgacgtg
    12721 tatccactgc aggttctttt ttctcaggga cgacttcaac cactgcttga acttgctgtg
    12781 cttgttcagc taacttagcc gcttcttcaa agatttcctc tggttccttg cgtttgttag
    12841 cttgagccaa ggcttcttta gcagcctgat actgcttgaa gcgttcctca cttgaacgag
    12901 cgtactctgc attttgctct gcttttaggg ctgctgcacg ggctttaaag tcaatacgtg
    12961 gagccgcttg atttgaacgt ttgtcctctt gctgacggcg ctcatttcta cgtttttgct
    13021 gaccttgctg cttcttagct tggtcattaa agcgacgatt gtcgcggttg ctttgacctt
    13081 gttttccacc attacggcca tcgtttttct gacggtttcc gttttgttgt tggtcacggt
    13141 tattgccctt attttgcttg cgtcgttctg cctgctcttt agcacgggct tcacgctcag
    13201 ccttgaaatt acggctttgc ggtttcgctg ctactttttc tgttttcgga gcaactggct
    13261 cagccggttt tgcctcttcc ttagctacag ctggtttagc tggctcagat ttttcggttt
    13321 tcttttctgc acttactttt ggtgctgcag gttttgcttc tactttcgga gcagctgcag
    13381 gcttaaagct ggcagcaatt tttgcagcga cagcttcttc cacacttgat gagtggcttt
    13441 tcacatccaa gcccaactct tttgcacgcg ctacaacttc tttactttct tttccaagtt
    13501 cttttgcgat ttcgtacaat cttttcttag acaaatcatg tcctcctctt ctattccata
    13561 agagacctca ttttctttgt aaatccagca tctgttacag ccaaaacctt tctcgatttc
    13621 ccgactgcta tgcttaattc cagtgttgaa aacacggtta caatttctac ttgataataa
    13681 tgacttttat cttgaatctt cttggtcaga ttgggtccag catcatgagc tagaaagacc
    13741 aacttggcct tgccgtcttg aatggccttg accaccaatt cttcacccga tatgatgcgc
    13801 cctgctcgct gagcaagccc caagagatta cttatctttt gcttattcaa gtcccaactc
    13861 tcttcttttc actttgtgat ccacataagc gatcaactcg tcataaaagc tttcttccac
    13921 ttccatgcta aagctgcggt taaagacctt cttctttttc gcctctaggg cttctgcatt
    13981 gtctagtttg atataagcgc cgcggccatt ggccttgccc gtaggatcaa taaagacttg
    14041 tccttccttg ttcttgacaa tgcggagcaa atcacgctta tcaatcactt cgttagacac
    14101 aacagacttg cgcaaaggga tttttcttgt tttcatcttt ccctcctcta gcagctttta
    14161 ttcttctaca gtatcgtttt ctacttccaa ctctactgaa gcagcgtctt ccatggcttc
    14221 aaattcgcta gcagacttga tatcgatacg gtaaccagtc aagtgagccg ccaagcgcac
    14281 gttttgtcca cgacgaccaa tggcaagaga aagcttgtta tctggaacaa ccaccaaggc
    14341 acgtttgctg tcgttttcat caaagataac ttggtcaacc tcagcaggag cgatggcatt
    14401 gtagataaat tcagctggat ctgctaccca ctcgataaca tcgatatttt cttcgattgg
    14461 taccatgcgg tcatttttag catcgtaacg agctgggtgg aatttgctag taatcttctt
    14521 gatattagca ccaccacgtc caacgattgt accgatagca tccacgtttg gattgtggct
    14581 acgaacagca accttcgtac ggtcacctgc ttcacgagcc acgctcatga tttcaacagt
    14641 tccatcataa acttctggaa tttcttgctc catcaaacgt ttgatcattt ctggatggct
    14701 acggctaaca aagacgttca caccacgagg gttgtcttca accttgtaaa cataaacttc
    14761 gatacgatca tgagaagcaa aaacttctcc aggaatttgg tcttgttttg acaattgggc
    14821 ttcgatgcta ccaaggttga catagataaa gcggttgtca aagcgttcta ctgtaccaga
    14881 catgatttct tgctcatgtt ctttgtaagt attgtaagtg atggcacgtg tttgcttgcg
    14941 cattttttcc atgatggttt gtttggcaga ttgggctgct acacgaccaa actcagctgg
    15001 tgcttcttca aacttgattt tgtctccaag ttcataagct gaattaatgg caagagcatc
    15061 tttcaagctg atttccaaac ggctatcaaa tacttcatca acaacttcac ggacagtata
    15121 aactgtaaag tcacctgttt tttcgttgaa gtcaatagct acgctgtctg actgaccata
    15181 gcgtctgcga taagcggaac gaagcgactc tactactgcg tcgatgatat cttctttttt
    15241 gattcccttg tcttcttcca aaatgcggaa ggcctctagc atttctttac tcatgttttc
    15301 ttcacttttg aatcctcaaa agctatcctt tctttttcta taatttaact gctaaacgtg
    15361 cttttgatac taaactgtat ggaatttgga cggttttctt acgcgtcttg cccatatatt
    15421 ccatagtcaa ctcgtcctct tcgaaggcca acaaggttcc ttcaaagacc ttttgcttat
    15481 cgatggcttg gtagagcccg acatggatgt attttccaac cgctccagcg acggcatcct
    15541 tggttttcaa agggcgttcc aaacctggac tggtaatttc taggaaatat tgttctggga
    15601 agggatctgg cttgatggtg tctaggacag gactgataat ttctgtcaag tctgccgtgt
    15661 cgttcaaggt aattccttcg ggtttatcta caaaaatact gagaatcatg tcactgccaa
    15721 tctttccata ctcgatatcc acgagttcaa aaggagcttc tatgacaggt tctacaactt
    15781 ctctgactaa ttctacgatt gttgcgattg cgtccacctc ctcataagca agaggcgaag
    15841 atatttcccc gcctcacttt tcatattctt actatcagta tagcacgttt gccaacttat
    15901 gtaaagcaaa agcacttgta cagcctaatt ttaggctatc tcttaaaatt ctgcctcaac
    15961 tcggtagata acttgcccct tgtttgagaa tttttgctcg tattctgtca tgacattgcc
    16021 ttcaaaatca ctggcatgca aatctaacca gacaccattg agtttcatgc catattgaga
    16081 aaagctcact aaactgtact caaacaagcc acggttatcc gtcttgaaat gaatttctcc
    16141 attttcaggc aagatacgtt tgaaggtatc caagaaggtc ttgtaggtca aacgacgctt
    16201 ttcatggcgt tttttcggcc atggatctga aaagttcaga tacaagcgat caatctcacc
    16261 gtcttcaaag tagtcagtta agtcagaacc atctacccac aagagcttga tgttaggcac
    16321 tccaacttca agcaccttgt ccaaagcgta gctcaaaaca gacttttgaa tatcaatccc
    16381 gatatagttg atgtcagggt cttgcttggc catacctgaa acaaaggcac cctttccact
    16441 tccaacttcc acatgaatgg gattatcatt gccaaacaag tcccgccatt ttgccttggc
    16501 ttccaaggga ttgaggacca catactgggg atttgcctct agtaattctg ttgccccttt
    16561 acgatttcta actctcatct tctctttcca tacttgtctc ggaaatgacg caaaccatga
    16621 atctcccgat tgacattttc taaatcttgg ttcatataat acttggaaat ctgactcaaa
    16681 taagacaatt gaccatacca atacaattta cttaataccg tttgattgta cttgtaaccg
    16741 tagtaggtca accattcctt ccactgatgt tctgaaatat aatggcagag catatgggcc
    16801 acatcaaaca tgcgatcggt caagcgaacc gaatcccaat ctactaaata aatcaagcca
    16861 ctatctgtct caatccaatt actatgtcgt acatctccat ggacaatggt cgcatggtcc
    16921 tctctaaatc ctggaatagt ctgacgtaaa tcagccatca cttcactgat aaaatgattt
    16981 ttacgcaaag catctggagc cgtttcctgc caagactgta gtaaatctac aggtgtttcc
    17041 atggcatagc ccaaacgact caattgtgtc atcaacggac gtgagcgatg aagacgggtt
    17101 aaaatattga cgatttgctt acgattcata tcataggggg tcaatatctt gcctgtcaac
    17161 cattcttgag cacacatatc acgcccatct gccaaacgac gactccataa taattgtgga
    17221 gcaatttgtt ctctagctag accaggtagg attggagagg tgttcatttt tacaaagatg
    17281 cgcttcccat caggatagct acccatataa gccttgccac ttttcccagg tatgggagtc
    17341 agtgttagct cattatcacc caaatccatt tctttcctcc gtataaagtt tccttactat
    17401 tctactagtt tttggcctat tcgtcaacca ctctaacccg attctcaaag aaaagcctct
    17461 ggattggctt gggtatcatt atagcttgaa aaaggtaagc accgtcttct gcttaccttt
    17521 tcataatttt tataaataat ataagagtgg ccaactgttg taaagcatat ggactagagt
    17581 agaaacccat aggttttgac tctttttata agcaaagccc agcaacaaac ccccaagtag
    17641 ataaaaaata aacgaaggga cattagaagg tccatgcatg aaagaaaaga gagaggaagt
    17701 tagcacaagc cctaaccaag aattgtcaaa aaccgcacct tgaagaagtc ctctgaaaat
    17761 gagttcctcc tggatggggc caaaaactga ggtagtcaaa atcaaagaca gggaaattcc
    17821 tctgctgact tccgccaagt gttggacccc tgagccagaa gaaacagcga agaaatgaat
    17881 ataaaccagc gtctcaagta cacttagaag aaagattgca atgaaaagca aaagttgttt
    17941 cttgcttaac atcccaaaag aaatcatttc aaactttcta gcataagcaa cactcagcga
    18001 ggttacaaga agacttacaa gaatcaatgc agattcattt tgaaaaaaac ccccatggtt
    18061 aatcgtataa ggaactgtaa tgacaattat tagtactaaa aatccaaaac acaaggcatg
    18121 aaatttatca aaaaactcca taaaattatc ctcctcaaca aacagacttc ctacacgtca
    18181 ttctttagtt ctagcctttc caaaacaaac cattttatac tcttcgaaaa tcaaattcaa
    18241 accacgtcaa cgtcgccttg ccgtactcaa gtacagcctg cggctagttt cctagtttgc
    18301 tctttgattt tcattgagta ttagtaacca aaatccgacc acatagccag cccctatgaa
    18361 tatagccatt aaagctagca tggaatttag gaaattaaaa accaccgcag atacaaaggt
    18421 tagcacaaaa acattaaaag caatggtgtc agaagccaag actagaatat agggtgtcaa
    18481 ccgatctaaa gttttggaat ctaggaaaaa taagtgttta tacatgatga cctcctctat
    18541 ggctgaaaag caagcctttt gtttttttac cccaagaccc tatgtagaaa agtgagcaaa
    18601 aacgggaagg tcgctacaat attattgatc acatgcaccg cataggatgg ataaatgctc
    18661 ttggtatagc gggtcaaacc agcaaagatg attccaactg ttgcaaagac gaagatatct
    18721 aacagactag gcaggcttga aaaatgaggg agagcaaata aaatagaagg aagaagcaaa
    18781 tcaagaccaa atcgcgaatg cttaaagaaa gcatgttgca gtaatcctct ataaatcaat
    18841 tcttccatca gtggaaccag aaagaacagg gctatataaa tacctagctc tgcaaagtta
    18901 gtcccactat aaccaatcaa tacagcccaa ccttccgcag ttgactgaac atgtttagct
    18961 gtctgaacgt taaaagagat ctggaacact accactaata ctgtcaaaat cgaataccaa
    19021 agccattttt ttcttggaat gcggaagaga taaccatggc ctgtcttaac aagaaccaca
    19081 atcatgactc caataaaaag taaactcaag atattttgaa tccagaataa attgcctatc
    19141 tgagaagaaa attgccaata gttttggacg ataagcgtca gctgagaaag accaaatacg
    19201 aaaaataagt aagagaagac tgcacttatt ttgaatagaa gttgatactt tttcatagaa
    19261 atcctcccta ctataacctc accttgtcag gctctactgc tgtaagatta agaagacagt
    19321 ttgttttttt taaggctaac ctgactacta gataatagat acattaaggc attaaagaca
    19381 atgaaaatat gtccatagaa taaaatcaac ctcgcatcca aaccaagata aagtttgatt
    19441 atcaaaaaga tgagcaaaag aatttgaaac cataaggttt ttccaaaaat aaatttaaag
    19501 cgatttcgaa tatctacttc cttgattttt accgccaccc ctttattagc aagaaggaaa
    19561 actcctgctt caaacaaacc actgtaaaga acaagccacc caatagatac gatagagatt
    19621 tgtaaaaatg tccctaaaag aatatccaac acactactca agaaaataac aaaaaataat
    19681 ctgtatttca tattaaatac ctccattcat ttatttcact aacaatttaa tagagccttc
    19741 tactcaaata tcctgtcaga aaaggataga aagctacttt ttataatact tcaagcccca
    19801 catgagcaga agcgtgataa acaagcagag aatacaccta tataagcgat tagttgttga
    19861 tagaattctg tttctgaaat acctctatac aaacaaatga caaacataaa atctgccaag
    19921 ccgataaaca taagttgatt ggttctagga ctaaccaaat catcatttac ttatatttaa
    19981 gagtatctct tttatgttag tgtatgttaa cactaaaaaa caagttaggc caataatatt
    20041 taaaatgaac aataacgggg ttaagtctct aaaaaaatta tctactgaca ctacaagaaa
    20101 tactatacat attatagtcg aaactatctt tttcttatcc ataattattt actcctttcc
    20161 taacaaatcc aacttatcaa tcaagagcga tttttaacat aatgtagcag cacccgttgc
    20221 aactttgaca agtttagtat atcattgttt tttaaaattt ttcatccaaa tcttgaattg
    20281 tcatcgaaac ctcctaaatt gcaaaaactt cattagcccc tactttttat aatacttcaa
    20341 accccaaatg agtagaagca tgatgatcaa gcaaagaata gcaccaatat aagcgattag
    20401 ttgttgataa gattctcctg ctgtgatacc tctatacaaa caaataatag acataaagcc
    20461 tgtcaagccg ataaacatga gttgattggt tctaggacta accaaatcat cgtcttcaaa
    20521 ctcttttatc cgcatttccc tagtgaggta aacagtgacc aaaatagaag ctaagttaat
    20581 aaccactaaa agaaattgga aaactgacga aatagaaata gataagtaga aacaagcaaa
    20641 ggcaactgcc ccaggaacaa tctcacaaag aatatgattc tttttaatca agaaaatctt
    20701 tcatttcttt tctttctttt taattaaaga aaaatagatc ataaccgcaa tcatataggc
    20761 tatggtataa aatagattat accaaatact ctccctaagc ggataaagaa agatggacat
    20821 gatcagatac agaacgaaaa taatcagtat ttttttcttc ataagatttc ctcctaaatg
    20881 tgcgatttat cttagttgag caagaacatt tacactgcta gtatagcact tattttgacc
    20941 ttggatcact caaatcataa atggtcatca aaacctcttg aattgtaaaa attaaaaaaa
    21001 gcaagcatga aaaacatact ttcctcttta tgttgtattg ataccaactt gtttgtagac
    21061 ttttcatcct gctatcacat atcattttga caggcgaaac aatattaaag aaactcccct
    21121 gtaaattaag ctagcaaata caggggagaa atttattttt tagagagtac tatccgtatc
    21181 ctttttggaa gattttgaaa atatttttct aattaagtca tccatataag gaccaaatat
    21241 accaactact aaaccaataa taaaactttt aaaatccata attaccacca acatgttgct
    21301 acataggcta cacctccaag tatagctcca cctgcagcac cagttacacc tattcctata
    21361 gcaaatggtc ccaatagaaa tgtcaaaccg ttgttgcaca cccatcaatt gcgccatatg
    21421 caacccctgc tgcacaacta atttttcttc cccaatcaat atctccacct tcaacgcaag
    21481 caagcatttc attatccata acagaaaatt gtgacatcat ttttgtattc atatagtatg
    21541 tcacttttca gttacggaac aagtttaata taaaaattat caaaaaaaca taggcaataa
    21601 agagaaaaat taatttatca tagattagaa ataatatgac aaaacaattc aatgatgtta
    21661 attcaatagt cttttgtttt ttatcagaga tacttatgga tagataaata agataggttt
    21721 gaaaagcgaa gagaataata aagaatatag ccttcataaa atttagcttt catttttatg
    21781 atgtagcggt ataggctaaa tatccacaaa ccactgctcc tccaattcct cctattgcag
    21841 cgccccatgg tcctagaatt ttcccatatt tcactccacc cgctgcacaa cctaaagcag
    21901 caactacagc tgctcctccg gaattacctc cataaacctc actcagcatt gtttcattta
    21961 tattacaata agtattcata caagtctcct tttattaaaa tccacccgtt gcccctgtta
    22021 ctcctgccca aagatccaca ccaaatttag ctcctatgta tccacatgct cccataaatg
    22081 gtgctccaac accactcgca gcacaaatag ctgtccctag cccccagcca ccaaaagcag
    22141 caccaccacc ttctaagaca ttagtttgcc aattattctt gcctccttca atactagata
    22201 acatagttat atccatttca tgaaattgtt ccatcatttt tgtattcatg acaaatactc
    22261 ttttttattt ttaatttttg tcttgttgta actttgacaa gtttagtata tcatcgtttt
    22321 ttaaaatttt tcatccagat cttgaatagt catcgaaacg tcttgaatta gcttttcatt
    22381 tgaaaccacc tctaaatttt ttaaaaaaag ataatttcta attatttttt accattcagg
    22441 aagtttcaat gactattcaa gatttaataa aatatgaact tatttttatg gcataatata
    22501 cctatctact atatgaaagg aattgccaat gacttcttat aaacgtacat ttgttcctca
    22561 aatagatgcg agagactgcg gtgttgctgc cttagcctcg attgctaaat tctatggttc
    22621 agatttttct ctagctcact tgagagaact tgcaaagacc aataaagaag ggacgactgc
    22681 tcttggcatt gtaaaagccg ctgatgaaat gggctttgaa acaagacctg ttcaagcaga
    22741 taaaacgctc tttgacatga gtgatgtccc ctatccattt atcgttcacg ttaacaaaga
    22801 aggaaaactc caacattact atgttgtcta tcaaacaaag aaagactatc tgattattgg
    22861 tgatcctgac ccttctgtaa aaatcactaa aatgtcaaaa gaacgctttt tctctgaatg
    22921 gactggagta gctatttttc tagctcccaa acccagctat caaccccata aagataaaaa
    22981 gaatggtcta ctaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat
    23041 tgttctctca agcttattgg tcactattat caatatcggt ggttcttatt atctccaagg
    23101 aatcttagat gaatacatcc caaatcagat gaaatcaact ttaggaatca tctcagttgg
    23161 tctggttatc acctatatcc tccaacaagt catgagcttc tccagagatt aagcattgat
    23221 gtgattttat cctatattcg ccatattttt gaacttccca tgtctttctt tgcgacacgt
    23281 cgtacaggag aaatcatttc acggttcaca gatgctaact ctattataga tgccttggct
    23341 tctaccattc tttctctttt tctggatgtt tctattctga ttcttgtagg gggcgtctta
    23401 ctggcacaaa accctaatct cttcctcctt tctcttcttt ccattcctat atacatgttc
    23461 atcatctttt cttttatgaa acctttcgaa aaaatgaacc atgatgtcat gcaaagtaat
    23521 tctatggtta gctctgccat tatcgaagat atcaacggga ttgaaactat aaagtcgctc
    23581 acgagtgaag aaaatcgcta tcaaaatata gacagcgaat ttgtagatta tttggaaaaa
    23641 tcctttaagc tcagtaaata ttctatttta caaacgagtt taaagcaggg aacaaaatta
    23701 gttctgaata tccttatcct atggtttggc gctcaattag tcatgtcaag taaaatttct
    23761 atcggtcagc tgattacctt taacacactt ttttcttact ttacaactcc tatggaaaat
    23821 attatcaacc tccaaaccaa actccaatct gcgaaggtcg ctaataaccg tttgaacgaa
    23881 gtctatctag tcgaatctga atttcaagtt caagaaaacc ctgttcattc acattttttg
    23941 atgggcgata ttgaatttga tgacctttct tataagtatg gttttggacg agatacctta
    24001 acagatatta atctcacgat taaacaagga gataaggtta gcctagttgg agttagtggt
    24061 tctggtaaaa caactttagc caaaatgatt gtcaatttct ttgaacccta caaagggcat
    24121 atttccatca atcatcagga tattaaaaac attgataaaa aagtcttgcg ccgtcatatt
    24181 aattacctac cccaacaagc ctatatcttt aatggctcta ttttggaaaa cttaaccttg
    24241 ggcggtaatc atatgattag tcaagaagat attctaaaag cttgtgaagt agctgaaatc
    24301 cgtcaagaca ttgaaagaat gcctatgggc tatcaaactc agctctctga tggagctggt
    24361 ctatcaggag gacagaagca acgaatcgct ctcgctcgtg ctcttttaac taaatctcct
    24421 gttttaatac tagatgaagc tactagcggt cttgatgtct tgactgagaa aaaagttata
    24481 gataatctta tgtccctaac tgataaaacc attctctttg tagcccatcg tctcagtata
    24541 gccgaacgaa ccaaccgtgt cattgttctt gaccagggga aaatcattga agttggtagc
    24601 caccaagagt taatgcaggc gcaaggtttc taccatcatc tattcaataa ataaggagaa
    24661 tgtcatgaat cctaatcttt ttagaagcgt cgagttttat cagagacgtt accataacta
    24721 tgcgacagtg ttaattatac ctctttcatt actatttact ttcatcttga ttttctccct
    24781 tgttgccaca aaagaaatta ctgtcacttc ccaaggagaa atcgccccta caagtgtcat
    24841 ttcatctatt cagtcaacca gtgataatcc tatccttgct aatcatttag tggcaaatca
    24901 agtagttgaa aaaggggact tactcatcaa atactctgaa acaatggaag aaagtcagaa
    24961 aactgcctta gcaactcaat tacaaagact tgagaagcaa aaagaaggac ttggaatttt
    25021 caaacaaagc ttagaaaaag cgactgatct tttttctggc gaggatgaat ttggctacca
    25081 taataccttt atgaatttta ctaaacaatc ccatgatatt gaactgggta tctcaaagac
    25141 taacactgaa gtttcaaatc aagctaatct taccaatagc agttcatcag ccatcgaaca
    25201 agaaattaca aaagttcaac aacaaattgg agaatatcaa gagctgagag atgctatcgt
    25261 aaataaaaga gctcgcttac caactggcaa tccgcaccag tcaattttaa atcgttatct
    25321 tatagcctct caagaacaaa cacaaggaac ggcagaggag ccatttttat ctcaaattaa
    25381 tcaaagtatt gcaggtctgg aatcatctat cgcaagcctc aaaattcagc aagctggtat
    25441 cggaagtgta gcaacttatg ataatagttt agcaaccaaa attgaagtac tccgcactca
    25501 gtttttacaa acagcctcac agcaacaact aaccgtggag aatcaattaa cagaattaaa
    25561 agtacaacta gatcaagcga cacagcgctt agaaaataat accttaaccg ctccaagtaa
    25621 aggtatcgtt catctgaaca gcgaatttga aggtaaaaat agaattccaa ctggtacaga
    25681 aattgctcaa atattccctg tcatcacaga tacaagagaa gtactaatca cttactacgt
    25741 atcttctgac tatctacctc tactagataa aggacaaact gtaagattaa aactggagaa
    25801 gattggaaat cacggcacca ccatcatcgg ccaacttcag acaattgatc aaactcctac
    25861 cagaacagag caaggaaatc tctttaaatt aaccgctctt gcaaaactat ctaacgagga
    25921 tagtaaactc atccaatatg gcttacaagg tcgcgtcact agtgtaacta caaagaaaac
    25981 atattttgat tatttcaaag ataaaatttt aacccattct gattaatttt cagataacac
    26041 tctataacta tttattatct tatcaaaaag gagaatcata acatggataa gaaacaaaac
    26101 ctaacttcat ttcaagaact aacaactacc gaactcaacc aaattatagg tggaggatgg
    26161 tgggaagatt tcttatatag atttaatata attgaacaaa aaaatacaaa aggatttcat
    26221 cagccaatac aactataaaa aaacaagacc aagagaacgc actctcggtc ttattttttc
    26281 ttcattctat atgtattaca gtaagtacct gacgaaaaac gtgatcttgg caggtggtat
    26341 tgagactggt attgggatga ctttccacaa ttttcataac ggtatagaga ccaactcctc
    26401 tctcctcccc tttagaactt gctccaaagg agaagatttc agaaatatcg attccctctt
    26461 ctttgatgga attttcaatg ataaaggtct cctgtgctcc atttttaaaa aaggcaattg
    26521 aaacatgagg ttgacaggct tctacactag cttcaatagc gttgtcacaa aggatagaca
    26581 caacggttag aaaatcaagt agactcatcc cctctacctg aatctcctct ggaacttcga
    26641 cattaaagac aatgttctta tctctagctt ttataaattt tccagctagg agacttttga
    26701 gggcacgatc ccgaacattc accaatcggc caaggtcata tttattgtcc tgcaatttct
    26761 gactggaatc ccttaagacc gagtcgtaga tctcttttat ctgctccata tcctcctctt
    26821 caatgcccaa acgtaagctg gttaagaggt tagtgtagtc atggcgaaaa ctccgaattt
    26881 ccttgtaaag ttcctctata tgccgactat agcgttccat atctctgtag cgcaaggtct
    26941 gctcttggtt cagttcctcc tgaagttttt ccttcaaata ggtatccaat ttcttgatac
    27001 cccccataaa aaagagtagg taaaacacta ggatgagatg gcgaacagtc gttgattgaa
    27061 taccttgttc atattcaagg taagatagac tttgcatcac tagataataa gcccccattg
    27121 cccagttaat cttagtaaga gacttttgaa aacctgtatc tagaaactcc cttctcaatc
    27181 tagtgaaatc atagtctaac catttcaaaa agactaaaac tatgaagcaa acgaatatca
    27241 taatcaataa aaagatagga ttgccatccc catctacaat tccttgcccc aaaaatggaa
    27301 gcacaaaata ggaaacacct ctgtaaaaga gctctactaa tatcattggg aagagaccat
    27361 aaaaaataag gattttttta ggaagccctc ttaacaataa gaaagataga cctataccga
    27421 acaaaggttc tataaaatag gacaaatatt tacttacagc caaaaattga aaagtcgtaa
    27481 aaatgatccc tagaagaaat ttcagaagaa aggccttaaa aatcctctcg aaagtaagat
    27541 caattccatc caccttaaag aagatgacaa tttctagtcc attagtaaca agtgtataca
    27601 acaatatcca agcaatgttc ataaattctc ctagctcagt gtaatttatt gatggcctca
    27661 gacacttccc tgaccttata acgggcgatt agacaacttc caccattggg aaagaaaagc
    27721 agtttttctt tcttatccaa atgcaccaca tttgcaggat tgatgagaaa agagcggtgg
    27781 cactgcaaga gacggggctc ctgcttgaaa acctcctcta aactcgctgt aaattccagc
    27841 ctgtctgtct tggtatagag aataacacga tgggctctgg gcgacgtttc gagatagtaa
    27901 acctctttaa aaggatactg aaattgggca aattttgatt taaagtaaaa gcaatcttcc
    27961 gccagacttt tactatcttg actattggca tagaggaggg ctgtctcgat ccgagattca
    28021 aactcctctg ctgacaaggc cttatcaatg tagtccaaag cagacacttg gtagcgaaaa
    28081 gacaggggca taaactccga gtgagtcgtc acaaagacaa tcagggcata aggatcccga
    28141 tcccgaatct ttctagccac ttccagtccc ttcatctctt catttcgaat ctcaatatcc
    28201 aaaaagaata gctgatgggc ccccttctca tgcacttcag ccagcagttg gtccggcttg
    28261 ccaaatacct caaaagagct aggaatgata tgatgtgctt tcaaaagttt ctcaatcgtc
    28321 gtttcaattc tagtctgttg ggaaaaatca tcctctaaaa caaatattct catcttctta
    28381 ctctccctct ttcaaccatt tttgacgaat ttctctatag cgacgtctgg catacttgac
    28441 agcgtattga ccttcttctc cgagaaaaag gattctttct tgaaaatcaa tcgattttaa
    28501 tttatcaaga ttaaccaaac aatttcgatg acatctcatc aaggtttccc cacattggtt
    28561 ctcaagatta cttaaatttt gaagcatatt aaaactagct tcttctgtaa caatctgtac
    28621 ggtatgggct ttagttggat gtgtttggat atagtagata tcgtcgatgt ttactttata
    28681 gactgttttc tgcgtctgaa taatcatata tttcattgga ttctcctcct aagaaaagaa
    28741 taacagaaaa ggtctagccc aagcacaccc aatcctaaac agtctttgaa aactcctaaa
    28801 aggattattt tctacaacat catgatgagc ttacaactat tttatcataa aattcactca
    28861 gcgcaattca agacatttca atgacaatta aagatttgaa taaaaaaaaa gaattaaaag
    28921 tgataaacta acagtatcaa aacacagttg ccagaagtaa gactggcacc cagattaaag
    28981 gaggcattcc catgacagat acagacccca tcaaaagagc tcatactttg attactgact
    29041 taaacaaagc ctaccaagca tgcaaacagg caagcgctga cgacgtccgc tttcaggagc
    29101 aattaaactc tattcttggt tttctagcca aggctgaaac agtggataat cgattcttga
    29161 ttgaactaga aaaattttac cagacttcca gtcttctcat gggactcagc gctcttgatc
    29221 cagatgctcc aactcgcgcc gcttggcggg cctatgaccg cttccacttt gaccaagtca
    29281 agaccaagtt aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaagctgt
    29341 acttgagtac ggtaagacga cgctgacgtg gtttgaagag attttcgaag agtataagtc
    29401 tctacggacc aaccattatc ctgtagtaac aaaaaagaag ttgagacaga ctgaactcaa
    29461 cttctttttt agtgtcgtat cagcaatgtt agtcctgcat ctgacgtttt acctgataag
    29521 gcaaatacaa gactagtaaa accaaaccag ctcctagtaa ggctagaagg gctagttttt
    29581 cttggaaggt aatcaaccca acaactaatt ccacaagtaa aacaaaactg gtcaatcctc
    29641 gaactacctc ctgtaagcct ttttcctttt gccccttgtc cagcggaaag agttgggtca
    29701 aatactggta gtcaaaggca tgatagaggg ccagcaactg gaagagcaag aggtagttaa
    29761 agagaactac cactgctgtc gcaatccaag cttgctcgat aaaaacctgc gccagtacgg
    29821 aaagtaagag aagacgaaga ctgagagcaa agaggtcgcc atttcgcaga taagaacgca
    29881 gatagagatt ttgccaaatc ttcccaggca ccttctgaac agcctttaag ataaagtcca
    29941 gataggcacg acgcttaacg ctgtttgaaa ttcccttgac ctgcgtaaag agggcaaaga
    30001 aacgaagcaa gacttgctta cgcttgcttt cttgggaaat gacatagtcc cagtccagcc
    30061 cagtttcagt gaaaaatttg ctggcctttt gacgaaagtg gaaatatttt cctaccccca
    30121 ataaaagcac atagagcaga aaaactggca agccataacc cattgctaaa aataaaggcg
    30181 caaataacag caagaaaagg gtctgtacaa agagccaaaa gactagggaa atgccagttt
    30241 gacgcttgag atggagcttg atttcctctt ctccaactaa gagaaagagc ttgtctggag
    30301 cctccatata ggtggcaatt cctccccaaa gtaaaagtaa aacagacgta attcctacaa
    30361 acaaaaggat aggccaatga ttttcaggaa aatgttgtaa gagttgactg tactggtagg
    30421 ctagaaagcc caacaggaca agcaggaaca agacaaagtg gtcattgagc acatagcgca
    30481 gataaccaag acactcctta cgaaaggcct gctttctctt taaaaacaag tctttcatag
    30541 atcctcctct ttggtcagag ccaagtaaat atcattcaaa ctagcctcag gcatatcaaa
    30601 ggcttcacgt agttgcagga gattgccttt ggcacgcacc tctcccttgt gaagaatgac
    30661 aaaggcatca cacatcttct ccgccgaatc cagcacgtgg gtactcatga gaatagactt
    30721 gcccttttgc ttctccactt ccaaaagctg aatcaaatca gaaatagcca gcggatcaag
    30781 accaaggaaa ggctcatcca cgatgaaaag acttggatcc accacaaaag cacagataat
    30841 catgaccttc tgcttcatcc cttttgaaaa atgaacaggg aaccagtcta atttctgttc
    30901 caaacggaac atttttaaca agggctctac tcgttcgaaa gccacttttt gctcaatacc
    30961 gtaagccata gcaaccgttt cgatatgctc tctgagggtc aattcctcat acagactagg
    31021 cgtctcagga atgtagccaa tctgcttgcg gtagctagtc gcatctcctt gcagagtcag
    31081 gccattgata ttgatggagc cactataagg tgccaacaga ccgataatct cattgatcgt
    31141 cgttgatttc ccagcaccat tgagaccaat caaaccgacc aactgcccac tttcaacagt
    31201 aaaggacaca tctttcaaaa caggaacatg aacatagcca cctgtcaggt ttttaatttc
    31261 taacatattt tctccaaatc tggtataatg tagctatatt atatcaaaat tcagtacagt
    31321 agaggtagat tttatgtcag attgcatttt ttgtaaaatc atcgcagggg aaattcctgc
    31381 ttcaaaagta tatgaagatg agcaggtcct tgcctttctt gatatctctc aagtaacact
    31441 aggacacacc ttggtcgtgc caaaagaaca ctatcgcaat cttttggaga tggatgctac
    31501 gagcgccagc caactctttg cccaagtacc aaaagtagct caaaaagtca tgaaagtcac
    31561 taaggctgct ggtatgaata tcatttccaa ctgtgaagaa gtcgctggtc aaacagtttt
    31621 tcatactcac gttcaccttg tgcctcgcta cagtgctgac gatgacctca agattgattt
    31681 tatcgcccac gaaccagact ttgacaaact tgctcaagtc gctgaaacca tcaaaaacgc
    31741 ttaaggagtt gctatgaaat tatccaacct actgctattt gcaggagctg cagccggaag
    31801 ttatctggtt acaaaaaatc gccaaaccat cacagatgaa gtcttgaata ccactgaccg
    31861 cgttcaagct atcaaggacg atgtggatat tatccaaaac agcctgcaaa tcattaacca
    31921 gcaaaaagaa cttatcaagg aataccaaga agacttgact tacaagttta aggtcttgga
    31981 aaaggatatc cagactagac tagctgtgat aaaagaaatg cagggaactg aagataagta
    32041 aaaagagccc gacggctctt ttttaaaacg taaacaagtt atagtgaatt gaatttagaa
    32101 tagcacatca tagtttctaa agcattgtta gagattactt taaaatcctc ttatcaattt
    32161 gttcatattc tatttcaatc tactatatat atcccatcaa ctatgcatca taatttaggt
    32221 aactcatact caataaaaat caaaaagcaa actagaaagc taggcacaga ctgctcaaaa
    32281 caccgtttta aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt
    32341 gtggatagaa ctgacgaagt cagtaaccat acccatgaca agccgacgct gacgtggttt
    32401 gaagaaattt ttgaagagta tcattcacca tttcacaact aaatcgaaga ctttctgccg
    32461 taatgaaaac acctgaaaca gcttggtttc agctgtccgg aaactttaag acttaggttc
    32521 aaagtttagg tatggaactt cgaaggaggt cgctaccgtc cgtcattact taggaaagtc
    32581 ttaaaaaatc tataaagtaa aaagagcccg acagctcttt ttgtttatac tcaatgaaaa
    32641 tcaaaaagca aactaggaaa ctagccacgg gctgctcaaa acactgtttt gaggttgtag
    32701 atacgactca catatatacg gcaaggcaac gctgacgtgg tttgaagaga ttttcgaaga
    32761 gtattattct ccatcaaagg catcttttat atggtcaaag aagccttttt tctttggatt
    32821 tactttcaag tcaccagcag tcgcgaattc tttcaaggct actttttggc ggtcgttcaa
    32881 gcctgtcggt gttacgacat taacagtaac gtattggtca ccaactgcac cgccacgaag
    32941 gctcggtgcc cccttactac gtaggcggaa tttcttacca gtctgagttc cctctggaat
    33001 aaccaattca acatcaccgt gaacagttgg aatatctact gtatcaccaa gagccgcttg
    33061 gacaaagttg aggttgagat tgtagaagat agtcgttcct tcacgttcaa acttgtcgct
    33121 agcttctaca gaaactacta catacaagtc accataaggt ccaccgttaa agcctgcttc
    33181 accttgacca gcgaggcgaa tttgttgacc tgtttccaca ccagcaggga ttttcacatg
    33241 tacgctatga gcttgtttct catgacctgt tccatgacag gttgtacatg gatatttgat
    33301 ttcttttcct cgaccgtgac agacatcaca ggttacttgg cgacgcatca taccaagagg
    33361 agtctgcgta tcgacgttaa tgacaccagc gccatgacag cgtccacaag tgactggact
    33421 tgtccctggc ttagcaccag agccattaca tgtacgacag ccagcttcac gatgatactt
    33481 aacttccttc tcagttccga agatagcttc ttcaaaggtc aaattgacac gatactggag
    33541 atcatctcct tggcgaggag cgtttggatt gcgcgaagaa ccgcctccgc cgaagaaact
    33601 tgagaaaata tcctcaaaac caccgaagcc acctgcccca ttgaaaccac cgaaaccacc
    33661 agctccacca aaaccaccat tggcgcctgc agcaccatac tggtcatagg cagcacgttt
    33721 ttggtcgtca ctcaaagtct cataggcttc ttgaacttcc ttgtacttgt cctcagcacc
    33781 aggctccttg ttgatatctg ggtgatattt tttggaaagc ttacgataag cctttttgat
    33841 ttcgtctgcc gaagcgtttt tggatacccc cagacgatca taaaattcag tattgttcat
    33901 acaagatacc aagaccgtaa aattcgactg aaaaatagga aatctgacgc tggagcgacg
    33961 ctcctagaca gatttctctt ttttccgaga atttaggtcg ggttcaattc ctttctttta
    34021 tattgatgag ataatactcc agccactcgg ccctatccct ttttaccgaa aaacagaggc
    34081 tgggttgcaa cctctgtggt tagattattc atttgaaata aaaatggttg tattatctct
    34141 agtagtaatc ttcaaagacc ttttagctaa atcaaactca aatttattat agtgtgggtc
    34201 ttgtgtttta tataggtgta actcctgaca tatatgatcc gaaaagtaaa tcataacatc
    34261 tttaaacaca gaagtgtggt catatttact cttaccaaca gctacttctg taaattcttt
    34321 ataaatgaca tttccatttc tttccacagt caccagcatt tctgttggat tataatccaa
    34381 attaaataat tattcaaaaa aactttatct tttcatgata atctgcaatg tcagaaagat
    34441 tatttttatt aacactcata acactagccc cttatttttc agtaaactct ccgtctacga
    34501 cgtcatcgcc tgcgtttcct gttgcttgtg cgccttctgc tccttcttga gcttgttgcg
    34561 ctgctgcggc ttgttcgtag agtttcacag caaggccttg agctttttcg ttcaacgctt
    34621 caagtttcgc tttcatgtcg tccaagttgt tgtcttcttg agctttctta aggtcatcaa
    34681 gggcagcttg ggcagcgtca cgttctgcgt cgaagccttt accttcagtt tccttgattg
    34741 tcttttcagt cgcaaagatt gcttggtcta cttcattacg aaggtctact tcttctttac
    34801 gtttcttatc ggcttcagcg tttgcttctg catctttcat catgcggtcg atttcttcgt
    34861 cagtcaaacc tgagttcgat tggatgacaa tagtttgttc tttttgagtt ccaaggtctt
    34921 tggccttaac agacacgata ccgttcttgt cgatgtcaaa tgttacttcg atttgaggaa
    34981 ttccacgagg tgcagctggg atatcagtca attggaagcg tccaagagtc ttgttatctg
    35041 ctgccattgg gcgttcacct tgaagaacgt ggatatcaac ggctggttgg ttgtctgctg
    35101 ctgttgagaa gacttgtgat ttagatgttg ggattgtagt gttgcgatcg ataagttttg
    35161 taaatactcc acccattgtt tcgataccaa gtgacaatgg cgttacatca agaaggacaa
    35221 cgtccttgac atcaccagta atcacaccac cttggatagc cgcacccata gcaactactt
    35281 catcagggtt tactgatttg tttggttctt taccagtttc agctttaaca gcttcaacaa
    35341 cggcagggat acgagttgaa ccaccaacaa ggataacttc gtcgatttct gacaagctca
    35401 aacctgcatc tgaaagggct tgacgaactg gaacttttgt acgttcaaca aggtcacgag
    35461 tcaaatcatc aaatttcgca cgagtcaaag tcatttccaa gtgaagaggt ccagcctcac
    35521 ctgcagtgat aaatggcaag ctgatttgtg ttgaagttac accagaaagg tctttcttcg
    35581 ctttttcagc cgcatctttc aaacgttgca ttgccatctt gtcagtagac aagtcgatac
    35641 cgttttcttt cttgaattct gctaccaagt ggtcaatgat tttttggtca aagtcgtcac
    35701 caccaagttt gttgtcccct gcagttgaca atacgtcgaa gacaccgtca cccaattcaa
    35761 ggatagagac gtcgaatgta ccaccaccaa ggtcaaatac caagattttt tcttctttgt
    35821 cagtcttgtc caaaccataa gcaagagctg ctgcagttgg ttcgttaaca atacgttcta
    35881 cttcaagacc agcaatttta ccagcatctt ttgttgcttg acgttgagcg tcgttgaagt
    35941 aagccggaac tgtgataaca gctttggtta ctttctcacc aaggtagtct tcagcgtagc
    36001 ctttcaagta ttgaaggatc atagctgaga tttcttgtgg agtgtattct tttccatttg
    36061 cagaaacttt ttcagaagtt cccatcttag atttgataga gataactgta tctgggtttg
    36121 tgactgcttg acgttttgca gcatcaccaa cgatgatttc tccgtttttg aatgagacta
    36181 cagatggagt tgtgcggttt ccttctgggt ttgcgatgat tttgctttca gttccttcaa
    36241 gaactgcaac tgctgagttt gttgtaccta agtcaatacc gataatttta gacatgtgtt
    36301 tttctccttg ttagttaatt ttctattttt ctttttgata ctcttcttaa gtggcgacgc
    36361 cgtcagagct tgacttcgtc aatctctttg actaaacttt gagcctaagg tctcaaaatt
    36421 tgcgcaaata gcaccacggc gaagagtatc gtctttggtt cgcttcgctc actattacaa
    36481 agccaaacat attttatctt tcttcatagt ttattgtcgt ttcggacaag ttttctatta
    36541 tgtaaattgc gacacgagga gtcgaaatcg attttatttc gacgacgagt tagtaaggaa
    36601 gctaggcaaa cgtcatagcg attgccgttt tctgacgagt tgctttagct accgtcagaa
    36661 ttgccgaatc gaacacgccc taagctctga gtaaaaaaga tagattttct tgtgttcatc
    36721 gaacacttcg tcaatctcct atttttactg cgagcttttt acgagctttg tatcttagtt
    36781 atacaccact accattgctg ggcgtaggat gcggtcatgg agtttgtagc ctttttgaaa
    36841 gacttgggcg atggtatcta ctgggtgttc atcgtctgct gggagagttt ggatggccat
    36901 atggtagtta tggtcaaatt cgccatctgc tgcgatttct tcaattcctt cttctttcaa
    36961 agcgtgaatc aagctttctt gcaccatcgc caagcccttc ttcacatcat ctgtcaaacc
    37021 ttcaactgca agtgcacgct caaggttgtc aagagatggt aagattgctt ttgccaagtc
    37081 ctggctacga taacgttgca agttttgacg ttcttcattg gcacggcgtt ggatattttg
    37141 catttctgca tgagcgcgaa gatatttgtt ttcgaactca tctgcacgtt catttgccaa
    37201 gtccaactca gacttttcag gagttgtttc ttcagctgtt tccacaactt cctcttcttg
    37261 aacttcttct acttcttcat tttttatatc ttgggccatg ttcgcctcct ttaatgattt
    37321 caatcttaat gtacttcgta atgattactg ctgaggtagc ggtaaaaatc tgtcaacttc
    37381 atggtcaaaa cacggttgac cacattgact tgattgatta gctgttggta atccagatta
    37441 actggaccga taatggctag aattccaact cctcgataag gaatgaggaa cttactacta
    37501 atcaccgcta ggtcagctaa acaggactct tgaccgtctg caacacgaac attttgcatc
    37561 tgatcctcac gcaacccctc acgaatctcc aaggccacct tttgcggttg gtcaaagaac
    37621 tgataggctt ctagattggc aaaattcaag agattgacct tgcccgccat cacaatgttt
    37681 tcgttgaaca tttccttaaa gatgtgttca aagagatcga tgacattatc cgttgttgta
    37741 aagtaacgct ggataatctg cggaatctcc gtccgaatct tgtagtgaat atctaaaacg
    37801 gtgtgaccga ggaaacgttc ctgaatgatg ctcttcagtt tcagcaaatc ctcctgcaag
    37861 aagttccttg gaatcagaaa ctgactagta accgttcgcg actcgtctag ggtaaatacc
    37921 gccaaggctg tatgttgccc caaaacaacg atatcaaagg ctgtcaaacg ttgcctgctc
    37981 ggctcaacat ccagtgccac taccgtacag ccactcaggt ctgttagcaa gttagcagcc
    38041 tcttgcagaa tatcctccaa tttgaagaat tcctgatcaa aggctttgac aatctcatat
    38101 acctcatttt cagccagccg gtgaaaatcc agtgagtgtt tcacatagta ctgaaaacca
    38161 gcaacacttg gcatccgacc gcttgaagta tgagccttct caagcaaccc ttgtttttct
    38221 agttccgcca tgtcattacg aatggttgca ctgctagagt taatagactc ttgcaaggct
    38281 tttgatccga caggttcgtg cgttttggta aagatgtcaa taatcagatt taaaatatcc
    38341 tgctgacgct ctgtaaccat ctcatcactc ctctctgtct gatcaattag cactcaatgc
    38401 atccaagtgc taacttatga ttctattata cacccttaaa agagaatgtc aagacaaaaa
    38461 ctcaaaaaat tagcactctt ttatcaagag tgctaaaaat caatctgaag acctagaacc
    38521 ttgctattca tctactcgat atttcctttt tagtctgaaa taaccatgaa ttagataaga
    38581 aatcagaaaa gcatataaaa caaaaataag aaagaaagac atagaaagat cctctctaaa
    38641 caaactcgta caaacaacaa gaccacctaa gaaagtagtt gtacaggaac gaagtctaga
    38701 tcgcataact tcccatttga gccccttact catatagact tgatcctctg gaagtaaatc
    38761 agaagacgat ttacgaagaa tcgaacaaga acctgctcct atcaattccc aacctctatc
    38821 tctaaaatct tgcagttcat gcttatattt tttaagaaat ctagaatcat agatacggta
    38881 gatgacatcg tctggttgac attggtcaaa atagaacaaa ccaaaacgac tcgttctata
    38941 cctccaacct ttcaaatgca tctcatgtaa atattcttct tacttgtcca aatcaacaat
    39001 ggtgaaaatc cgaaattcta ctctgctatt cattgtctta ccccaaaatt agaaaacatg
    39061 cctggcgtta tttattagat aattctttcc acttttgact caatctccaa aaaatataag
    39121 aaatctgaat cgcaaaaact atcaataaaa cccaatctat tatgaaaatc aaaaacactt
    39181 tccaactgaa agaactacct ccagtgacaa actttgagaa aaacggtagt agagctaaaa
    39241 agagaagtaa aataggaagc atccgcattg ttaaaatccg tttggcataa aaaaatcttt
    39301 atttaaacta aaatattata tcaaaattta cgccagtttt tgaacggctg atgtagatat
    39361 tttatacttt caaaatgttt aaatgtgatt atttattttt gaaaaatagc tcaccagccc
    39421 gactgaaagt gcttatagaa tgataataag tcgcctgccg aaaacagcgg aaaatagcgg
    39481 tgttatgcgg agataatctg acgcgatgcg aaagtatatt gcatacttat tttcaacaat
    39541 ttagcagagt atttttataa gtgtgatata atagaagtat aatttgttct gatagtttat
    39601 tttatggaga agtagatttt tagaatgcgg agggttcaat atggttgagt ttataaagtc
    39661 taagaaagaa atgagtgagg aggatattaa agcaaatttc atcactcctg ctattgtatc
    39721 caaaggatgg aaaaatggtg agcatatcgc ttacgaagaa tacttcactg atggtcgaat
    39781 tgaggttaga ggagataagg ctcgtcgtaa agaaggaaaa aaatcagact attcactgta
    39841 ttaccaattt ggaactcgaa ttgcaattgt tgaggcaaag gataataaac acagcgttcg
    39901 agcaggatta caacaagcta ttgaatatgg agagatttta gatgttccat ttgtttattc
    39961 ttcgaatggt gatggcttta ttgaacacga ccgtatcacg agagaagaac gtgagctgga
    40021 gttagacgaa ttccctactc gtgaagaatt attttctcgt atgacgaagg aaaaaggatt
    40081 gacgtacgaa attacagaag ctatctcaac tccatactat acagacgcct tctcaatgaa
    40141 aacgccacgc tattatcagc aaatagctat caaccgtact attgaaacag ttgccagagg
    40201 acaaaaacga gtaatgtttg tgatggcaac aggaacgggg aaaacgttca tggcttttca
    40261 aattattcat cgccttcgaa aagctggttt ggctaaacga gttttattct tagcggatag
    40321 aaacatctta gtagaccaaa cgatggctga agactttagg ccattcgaaa aggtaatgac
    40381 gaaaattaca ccaaaacttt tgactgctcc tgaaaaatta aattcttttg aaatttatct
    40441 agggctttat cagcaactaa ctggtgaaga tggaactgaa acacattatc aaaaatttga
    40501 caaagacttc tttgatttaa tcgtaattga tgaagcgcac cgtggttcag ctaaggaaaa
    40561 cagtaactgg cgtaagataa ttgattattt cagttctgcg acacagattg ggatgaccgc
    40621 tactcctaaa gaaaccaaga atgcttccaa tacggaatac tttggtgagc caatctatac
    40681 ttatagttta aaacagggaa tcgaggatgg ttttttggct ccatatcgtg ttatgagagt
    40741 taatttagat gtagatgtgg atggttatcg tccagaaact ggaaaagttg atgctaacgg
    40801 acaattaata gaagataggt actacggcag gaaagatttt gataaaacca ttgtcattga
    40861 tgatagaacg caaagagttg ccaagtttgt ttctgattat atgaagcaaa acaatgcacg
    40921 atttgataaa acaattgttt tttgtgttga tattgaccat gccgagcgaa tgcgtgctgc
    40981 acttgtaaaa gagaatctag acttagtcca agaagactat cgttatgtca tgcaagtaac
    41041 tggtgacaac gctgaaggaa aagctcaact ggataacttt atggatgtca attctaattt
    41101 tcccgctatt gtaacaacgt ctaaattatt aacgacagga gttaatgcta aaacatgtcg
    41161 tttgattgtt ttagactcta atatccaatc catgactgaa tttaaacaaa ttattggtcg
    41221 tggcacacgt ctttatcctc aaaaggggaa agaatttttt acgattattg attttcgaaa
    41281 tgttaccaat ttgtttgctg accctgattt tgatggtgat ccagtgaagg tgctggaaac
    41341 aggtgcgaaa acagtcagtg gttctacgcc cggtttcgta agtgaggaag gtgacccagt
    41401 agaaaaatat atcgttacag acaagcaggt taccattctt aattctactg ttcaagtatt
    41461 ggatgaaaac gggaaactga ttaccgaaag cctgaccgac tacactcgga agaatatctt
    41521 aggtagctac gccactttga acgattttat cacagtttgg catacggcgg ataaaaagaa
    41581 gcttatctta gacgaacttt ataaaaaagg agtttatcta gatgctattc gagagtcgga
    41641 gggaatatca gaacaagaaa tcgatgattt tgatttactc ctaaaacttg cctatggtca
    41701 aaaagaatta accaaaacgg aacgtatcaa taagctcaaa caaagcggat atttatataa
    41761 atatagtgag gaagcgcgtg ctgttttgga aattttactg aacaaataca tggataaagg
    41821 tattggagaa ctcgaaagca ttgaaacatt aaaacttcca gaatttcaga tatatggtgg
    41881 aaccttcaaa atcatcaata cttattttgg agataaaaaa cgatatttac aagcaattaa
    41941 agaattggag caagagctat ttacagtagc ttaatgaaag gaaagtatgt caattacatc
    42001 atttgtaaaa agaattcaag atatcactcg aaacgatgct ggtgttaatg gtgatgctca
    42061 acgtattgag caaatgtctt ggttattatt cttaaaaatt tatgatagcc gtgaaatggt
    42121 ttgggaatta gaagaagacg agtatgagtc aattatccca gaggaattaa aatggcgaaa
    42181 ttgggctcat gctcaaaatg gggaacgggt attgacaggc gatgaattac ttgattttgt
    42241 caataacaag ttattcaaag agttgaaaga gcttgaaata acttcaaata tgcctattcg
    42301 aaaaacgatt gttaaatcag cttttaaaga tgcgaacaac tatatgaaaa atggcgtctt
    42361 gttacgccaa gtcatcaatg ttattgatga agttgatttc aatagccctg aagatcgtca
    42421 ttcgtttaat gatatttacg aaaaaattct taaagatatt caaaatgctg ggaactcagg
    42481 agaattttat acaccacgtg cagcgactga ttttattgcc gaagttcttg acccaaaact
    42541 tggagaatca atggcagacc ttgcttgcgg aacaggaggc ttcttgactt cgactctgaa
    42601 ccgtttaagt agtcaacgta aaactagtga agataccaaa aaatataata cagctgtttt
    42661 tggtattgaa aagaaagcat ttcctcatct tttagcagtt acaaatctgt ttcttcacga
    42721 aattgatgac cctaaaattg ttcatggaaa tactttagag aaaaatgttc gtgaatatac
    42781 ggatgatgaa aaatttgaca ttattatgat gaatccacct tttggagggt cagaattaga
    42841 aacaataaaa aataactttc cagcagaatt acggagttct gaaacagctg atttatttat
    42901 ggctgtcatt atgtatcgtt tgaaagaaaa tggtcgtgtt ggagttattt tacctgatgg
    42961 ttttctattt ggtgaaggtg taaaaactcg cttgaaacaa aaactggtag atgagttcaa
    43021 cttgcatacg attattaggt tgcctcatag tgtctttgca ccgtatacag gaatccatac
    43081 gaacattctt ttctttgata aaacaaagaa aacagaagaa acttggtttt atcgtttaga
    43141 tatgccagat ggttataaaa atttctcgaa aactaagccg atgaagtcag aacacttcaa
    43201 tcctgttcgt gactggtggg aaaatcgtga agagattctg gaaggtaagt tctacaaatc
    43261 taaatcattt acacctagtg aattggctga gttgaattat aatttagacc agtgtggttt
    43321 tccaaaagag gaagaggaaa tcttaaatcc ctttgagttg attcagaatt atcaagcgga
    43381 aagagcaact ttaaatcata agattgataa tgtattagct gatattttgc agttgttgga
    43441 ggacaaataa tgacaccaga acaacttaag gcaagtattc tccaaagagc gatggaaggg
    43501 aaattagtgc cgcaaaatcc caatgacgaa cctgcaagtg aattattaaa gagaattaaa
    43561 gctgaaaaag aaaaacttat cagtgaagga aaaatcaaac gagataaaaa ggaaactgag
    43621 atatttcgtg gtgatgatgg gaaacattat gggaagtttg ctgatggaag tactcaagaa
    43681 attgatgttc cttatgatat tcctgatact tgggagtggg tgaggataaa atcaatttat
    43741 tggaattttg ggcaaaataa gccagagaaa tcctttaggt atatagatac gtctagtatt
    43801 gatagaaaaa agaacataat caactacaaa aatctacaat atctttcacc tgaacaagcg
    43861 ccttcccgtg ctagaaaatt agtttcgcag aatagtgtct tattttcaac agttagacca
    43921 tatctaaaaa atattgctgt agttagagaa cttaaagagt atttgatagc tagtacagca
    43981 tttattgttt tggatacttt acttaacgaa acatatttga aatattattt attatcagat
    44041 aattttatca atcgtgttaa taataaatct actggaacaa gttatcctgc aatcaatgat
    44101 tataatttta atctattatt aattgctctc cccccactat ccgaacaaca acgaata
//
LOCUS       DAVLHM010000015        43244 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLHM010000015 DAVLHM010000000
VERSION     DAVLHM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43244
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.015"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            204..1196
                     /locus_tag="VXE45_000833"
                     /pseudo
     CDS             204..1196
                     /locus_tag="VXE45_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1198..2015
                     /locus_tag="VXE45_000834"
                     /pseudo
     CDS             1198..2015
                     /locus_tag="VXE45_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            2017..2802
                     /locus_tag="VXE45_000835"
     CDS             2017..2802
                     /locus_tag="VXE45_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788901.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(3181..4376)
                     /locus_tag="VXE45_000836"
                     /pseudo
     CDS             complement(3181..4376)
                     /locus_tag="VXE45_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            4878..5081
                     /locus_tag="VXE45_000837"
     CDS             4878..5081
                     /locus_tag="VXE45_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0788902.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSC"
     gene            5212..5364
                     /locus_tag="VXE45_000838"
     CDS             5212..5364
                     /locus_tag="VXE45_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788903.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            5531..7324
                     /locus_tag="VXE45_000839"
     CDS             5531..7324
                     /locus_tag="VXE45_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0788904.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            7429..8016
                     /locus_tag="VXE45_000840"
     CDS             7429..8016
                     /locus_tag="VXE45_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0788905.1"
                     /translation="MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYINQEFKSYIDHM
                     LNKEAKIIGFSAGPLLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELDNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            8298..8546
                     /locus_tag="VXE45_000841"
     CDS             8298..8546
                     /locus_tag="VXE45_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEV0788906.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILTYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            8722..8975
                     /locus_tag="VXE45_000842"
                     /pseudo
     CDS             8722..8975
                     /locus_tag="VXE45_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9103..10332
                     /locus_tag="VXE45_000843"
     CDS             9103..10332
                     /locus_tag="VXE45_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0788907.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLMMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            10352..13048
                     /gene="ppc"
                     /locus_tag="VXE45_000844"
     CDS             10352..13048
                     /gene="ppc"
                     /locus_tag="VXE45_000844"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0788908.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    13131..13348
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13461..14465
                     /locus_tag="VXE45_000845"
     CDS             13461..14465
                     /locus_tag="VXE45_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0788909.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPEFVLKEAGQVIE
                     "
     gene            14534..15400
                     /locus_tag="VXE45_000846"
     CDS             14534..15400
                     /locus_tag="VXE45_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0788910.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            15397..16155
                     /locus_tag="VXE45_000847"
     CDS             15397..16155
                     /locus_tag="VXE45_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788911.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            16245..18005
                     /gene="dnaG"
                     /locus_tag="VXE45_000848"
     CDS             16245..18005
                     /gene="dnaG"
                     /locus_tag="VXE45_000848"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0788912.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            18008..19117
                     /gene="rpoD"
                     /locus_tag="VXE45_000849"
     CDS             18008..19117
                     /gene="rpoD"
                     /locus_tag="VXE45_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0788913.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            19131..19460
                     /locus_tag="VXE45_000850"
     CDS             19131..19460
                     /locus_tag="VXE45_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0788914.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            19575..20618
                     /gene="cpoA"
                     /locus_tag="VXE45_000851"
     CDS             19575..20618
                     /gene="cpoA"
                     /locus_tag="VXE45_000851"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0788915.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            20634..21959
                     /locus_tag="VXE45_000852"
     CDS             20634..21959
                     /locus_tag="VXE45_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0788916.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            21990..22166
                     /locus_tag="VXE45_000853"
     CDS             21990..22166
                     /locus_tag="VXE45_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0788917.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIVPVATDY"
     gene            22225..22359
                     /locus_tag="VXE45_000854"
     CDS             22225..22359
                     /locus_tag="VXE45_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0788918.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            22423..23733
                     /gene="obgE"
                     /locus_tag="VXE45_000855"
     CDS             22423..23733
                     /gene="obgE"
                     /locus_tag="VXE45_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0788919.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            23743..23901
                     /locus_tag="VXE45_000856"
     CDS             23743..23901
                     /locus_tag="VXE45_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788920.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(23953..25279)
                     /locus_tag="VXE45_000857"
                     /pseudo
     CDS             complement(23953..25279)
                     /locus_tag="VXE45_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            26382..27641
                     /locus_tag="VXE45_000858"
     CDS             26382..27641
                     /locus_tag="VXE45_000858"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0788921.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            27657..28208
                     /locus_tag="VXE45_000859"
     CDS             27657..28208
                     /locus_tag="VXE45_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788922.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            28201..29478
                     /locus_tag="VXE45_000860"
     CDS             28201..29478
                     /locus_tag="VXE45_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0788923.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            29494..30354
                     /locus_tag="VXE45_000861"
     CDS             29494..30354
                     /locus_tag="VXE45_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0788924.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            30577..30687
                     /locus_tag="VXE45_000862"
                     /pseudo
     CDS             30577..30687
                     /locus_tag="VXE45_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            30733..31537
                     /locus_tag="VXE45_000863"
     CDS             join(30733..31101,31103..31537)
                     /locus_tag="VXE45_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0788925.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            31729..34020
                     /gene="pcrA"
                     /locus_tag="VXE45_000864"
     CDS             31729..34020
                     /gene="pcrA"
                     /locus_tag="VXE45_000864"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0788926.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            34063..34743
                     /gene="radC"
                     /locus_tag="VXE45_000865"
     CDS             34063..34743
                     /gene="radC"
                     /locus_tag="VXE45_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0788927.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(34740..35429)
                     /locus_tag="VXE45_000866"
     CDS             complement(34740..35429)
                     /locus_tag="VXE45_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0788928.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDSGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(35447..36088)
                     /locus_tag="VXE45_000867"
     CDS             complement(35447..36088)
                     /locus_tag="VXE45_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0788929.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(36171..36386)
                     /locus_tag="VXE45_000868"
     CDS             complement(36171..36386)
                     /locus_tag="VXE45_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0788930.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(36394..36741)
                     /locus_tag="VXE45_000869"
     CDS             complement(36394..36741)
                     /locus_tag="VXE45_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0788931.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(36746..37861)
                     /locus_tag="VXE45_000870"
     CDS             complement(36746..37861)
                     /locus_tag="VXE45_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0788932.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(37871..38830)
                     /locus_tag="VXE45_000871"
     CDS             complement(37871..38830)
                     /locus_tag="VXE45_000871"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0788933.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGAPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(38943..39512)
                     /locus_tag="VXE45_000872"
     CDS             complement(38943..39512)
                     /locus_tag="VXE45_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0788934.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            39640..40311
                     /locus_tag="VXE45_000873"
     CDS             39640..40311
                     /locus_tag="VXE45_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0788935.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            40295..41113
                     /locus_tag="VXE45_000874"
     CDS             40295..41113
                     /locus_tag="VXE45_000874"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0788936.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            41110..42006
                     /locus_tag="VXE45_000875"
     CDS             41110..42006
                     /locus_tag="VXE45_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0788937.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHLLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            42050..43024
                     /gene="pta"
                     /locus_tag="VXE45_000876"
     CDS             42050..43024
                     /gene="pta"
                     /locus_tag="VXE45_000876"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0788938.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT        13213 a         7454 c         9388 g        13189 t
ORIGIN      
        1 atccaattat aaatttatat gttcttcgtc ataattcttt gtacttgagt aatttagctt
       61 acttacagat aaaatacaag atggcatagt tttagtagct tttttcatat ggtttgtaat
      121 gatggtaaat tttcttaact ttactgtagt atgctacaat ttttgttgat attataactt
      181 gagtgaaacg aaaggagtga tttataaaaa tgataacagt agagcatctt cagaaaaatt
      241 ttgtgaaaac aataaaggaa cctggcttaa agggagcttt tcgctctttt tttcatccca
      301 agagacaagt ctttgaagct gttaaagatt tatcatttga ggtgcccaaa ggacaaattt
      361 taggctttat tggcgcaaat ggagcgggga aatcaacaac tatcaagatg ttgacgggga
      421 ttttgaaacc aacatcaggt ttttgtcgta tcaatggaaa gattcctcaa gagaaccgtc
      481 aaggctatgt taaagatatt ggtgtagttt ttgggcagcg aactcaactt tggtgggatt
      541 tggctttgta ggagacttac tcggttttaa aggaaattta tgatgttcct gatgcggtct
      601 ttcaaaaacg catggatttt ctaaatgaag ttttagattt gaaggaattt attcaagatc
      661 ctgtcagaac tctatctcta ggtcaacgta tgagggcgga tattgcggcc tccttattgc
      721 ataatccgaa agttcttttc ctagatgagc ctactattgg tttagatgtt tcggtcaagg
      781 ataatattcg acgtgccatt acacagatta atcaagaaga agagacgacc atacttttaa
      841 cgacccacga tttaggtgat attgaacagt tatgtgatcg tatttttatg attgataagg
      901 gccgagaaat ctttgatgga actgtgaatc aactgaaaaa gactttcggg aagatgaaga
      961 ctctctcttt tgaactacat cctgggcagg attatattgt ctctcatttt gaaggacttt
     1021 ctgatatcta tgtgacgaga caggaattgt cacttgatat tcagtacgac agctcgcagt
     1081 atcaaacggc tgacattatt caacaaactt tgtctgattt tacgatccgt gatttaaaga
     1141 tgacggatgc gaatattgaa gatattattc gtcgcttcta tcgaaaggag ctttaggatg
     1201 actaaattat ggaaacgcta taagcctttt gttagcgctg gaatccaaga attaatcacg
     1261 tatcgtgtca atttttttct ttatcgcatt ggggatgtga tgggggcctt tgtagcattt
     1321 tacttgtgga aagctgtgtt tgattcatct caccagtctc tcattcaagg ttttacttta
     1381 tctgatatga ccttatatat catcatgagt tttgtgacga atctactgac aaaatcagat
     1441 agttctttta tgattggatg ggaagtaaag gatggctcta ttattatgcg actgcttcgt
     1501 ccagttcatt ttgcaatgtc ttatcttttc acagaaattg ggtctagatg gctagttttt
     1561 gttagtgttg gtctaccatt tgtaattctg attgcaggtc taaagctctt atcaggtgag
     1621 tccttcttac aaattgtttt aataaccaca gtttaccttc ttagcttaat cttagctttt
     1681 ttgattaatt ttttttcaat atttgctttg gtttttcagc ttttgtgttt aaaaacttat
     1741 ggggatcaaa tcttttgaaa aattctttag ttgccttttt atctggaagt ttggttcctc
     1801 tgacattttt tccaaaaatt attgccgaac tattatcttt tttgccattt tcttctttaa
     1861 tctatacccc ggtgatggtt attatagaaa agtatagcat gagtcaaatg attcaggcgc
     1921 tctcgctaca attattctgg ctgtttatta tgattgcctt atcccaactg atttggaagt
     1981 gcgtacagaa ttatataact attcaaggag gttagaatga agaaatatca acgcatgcac
     2041 ctgattttta tccgacaata tcttaaacag attatggagt ataaggctga ttttttagtt
     2101 ggtgttgtgg gtgtcttttt gacacaaggg ttaaacatgc tgtttctaaa tattttgttt
     2161 caacatattc ccttacttga tggctggagt tttcatcagg ttgcttttat ttatggtttt
     2221 tctctcattc ctaagggaat tgaccatctc ttttttgata atctgtgggc tttaggacaa
     2281 catttaattc gtaaaggaga atttgataag tatttgacta gacccattag ccctttgttt
     2341 catattttag tagaaacgtt tcaaattgat gctcttggag aattgttagt aggcgtctta
     2401 ttgctgttaa tgacaataac tagtcttact tggacttggg caaaggtttt tctcttttta
     2461 atcagtattc cctttgcaac cttaatttat acctctttaa aaattgtaac agctagtatt
     2521 gctttttgga ctaaacaatc tggggcaata atttatattt tttacatgtt taatgatttt
     2581 gcaaaatacc cgattgcgat ttaccattcg tttttacgtt ggttgattag ttttatcatt
     2641 ccttttgctt ttacagccta ttacccagct agctatttct tgaaagacaa ggatggattg
     2701 ttcaatattg gtggattgat ccttatctca ttaatatttt ttaccttatc attaaaatta
     2761 tggaacaaag gtttggatgc atatgagagc gcagggtctt agaagaagta aaatctaatt
     2821 aagaattttg atagaacttc ctattctttg gaaggaagtt ttaatgatac attgagagct
     2881 ttgattaggc ttactgtagt ttttcaaaca agaaatttga ccattgtgca aaaatgatac
     2941 aaaggtatgt aatatttcag tcataaccac tcgttcatat catgagtggt tttttagctc
     3001 ttttatacat accatttgtt aagggacata cgatattcta gctcaaaagg ttttctgaat
     3061 gagtatcaaa ggaatgttta gaagataatt gcgagctgtt ttttgaaatt tgggcacact
     3121 taaaagacac ttatctggta ttaaaaaata aggtgttaca atgataggac atagatgact
     3181 ttaatgactt tgggttaaag tgtagtcgta aagtttgtta tgcgttatga ggtaatacat
     3241 tgtccggatg aggcgatgta tagagacaat cgtatatggc ttggttgaag tcgtctgcga
     3301 ttgtcttttt cgtttctcat aaaagtccgc gatatgacaa ggattggtat gactagctga
     3361 agcaatattg tggacgcact tatagagaat ttttctcgcg taaggatttc cacgcttggt
     3421 gatatgttct tgagctagga aattgccaga ttcatagtgt ctgaggtcaa tactgataaa
     3481 ggcattgatt tggttggcag accgaaagcg acgaatgtct ccaattcgcc aataatgctt
     3541 gtagctgttg tttctgcgat accaggaata gagagcagaa tctcgtattc aggtaatggt
     3601 tcagccaatt caatcatttg tgctaagtcc tgatccttgc ggtttgtcag tctcaacagt
     3661 tcctgtgcat gatacttaac ctcttctgtc atgggagagg tttttgaaat ggcaagatag
     3721 gactgttcgg ccagctcgct caacttttca gccaatcgtc caactctgtt ctcagaaatc
     3781 cgtttagaag ttgaattacg atggcttctt ttagctcaac tactgataat ttcagcctcc
     3841 aatgcttggt tggaaagatg gtcacgaggt tccaatattg ttcccctgta ggagtagaga
     3901 gaaggttctt tatttctgga aaggcaattt gaagcacctt gtgcaggcta ttcttagtcc
     3961 taacgatgtc ttctgtcaga ttctgataga atcgactgag gtcacgcaaa ttttgataga
     4021 cttcttcttg aacataagtt ggtttgcggt taaggatgaa ttgtgacgaa gctagctttt
     4081 cagcgtcaat ctgattggtt ttacggactc gcaaactgtc tagttgcttc ttagttttaa
     4141 aggatttagc cgtatataag catagctatt gtcctccaga aaggcctgaa gacgagaata
     4201 gacccctgtg cctcgaagat aatctcaggt gtatttacct atttcaaatc ctctagaaga
     4261 cgactaaatc cgatggcatc attgggcatg gtatagccat gaaccttttc accattcaca
     4321 agaatagcga cttctgagct tgccttactc acatccattc tgaaaactgt ccgcatcatg
     4381 tttacccctt tgtcttgaat gactccttgt tttagtgatt ttatttccaa tactcgacgt
     4441 ctagtatccc acatactttg ataaaattct tcctaaaaca ggtttcttgc cagtttgtca
     4501 agcgacgtct agcaccatag agagctctat gacttaacaa gacaccacta ttttaacaca
     4561 aagaaaaagt aatgagtact ctctcccgtt ggagatttcc tcactactaa tcttagtatg
     4621 tttgtcaact gtagtgatag acgaataatc aagttctgga gaaggtcaga ttgggcgatt
     4681 acttattatt ttcctagctt gtacggtgct tttatcgcta tgaaaaagtt tattccaaaa
     4741 tcttttttta gtaacttata gcttacttac tgttatacca actatttcta aaatcttata
     4801 aattatttta tgcatatttt gcataaaatt ccaaatttga taatcttcaa attacaatat
     4861 tagtaagagg attattaatg tatatcagat taaagaattt aagagaagac aaagatttgt
     4921 cccagtgtca aattgcacag tatcttcatt gttcacagtc tgcttattct agaatagaaa
     4981 gtggcaagca agatattcct acatcatttt tgaaacaatt agctaaatta tatcaggtaa
     5041 ctacagatta tattttagag atggataagt ttagttgtta ataaatccta agccctttga
     5101 aaactgaata aaccgaggtg ggactttctt atttgtcgag cactttagct tgatacgccg
     5161 tgataggagc gataattatt agctataaaa tagagtggtt ctctatctgc catgactaca
     5221 aataaggata atgatacttc tgaacgttca ggctgccagc gaaaaaggac agcgggtgaa
     5281 atgcccatga atgatttaac cagtcatacc cacggaggaa attatacatg ttacaaggag
     5341 gaaaaagttt ggaacaatca gtaataaagt atactatgca actatcaatg cttaactttt
     5401 tatactcaag aaatatgtta tctaaaaatg agtatgacaa gattagaaac aaactgcgta
     5461 ttaagtacac aaaatagctg actttttgat ttgaatgcgg taatatagaa tcaaaaggag
     5521 gaatttcagt atgaaaaaaa ataatgttga aataataaaa gctgattctt tagttcgtcg
     5581 aagaggcgac aatgtagaaa gacacttaaa gagggttgct gcttattgca gagttagttc
     5641 cgatagtgag gatcagaaaa acagttatga ttctcaagta agacactaca aagaatatat
     5701 ttctcagcgt tcagattggg agctggcaga tatttatgca gatgaaggta tttcaggaac
     5761 acaagtagga aagagacaag attttcaacg attaatcaat gattgtgcaa atggagagat
     5821 agattatatt gtcacaaaag caattgctag atttgcaagg aataccctag atactttgaa
     5881 gtatgtcaga atgttaaagg atatgcaaat tggagtatat tttgaggaag aaaacataga
     5941 taccctaaca atggatggag aattgcttct aactattcta agctccgttg cacagcaaga
     6001 agtagagaat acttctgccc atgtgaaaaa aggattaaaa atgaagatgc aacgtggtga
     6061 attggttggt tttcaagggt gcttagggta tgattatgat gtagaaacca agcagatttc
     6121 aattaataaa aaagaagcca aaattgttcg ttatattttt gaaaggtatc tagaaggtat
     6181 tggaggaaaa gtaattgcaa gggaacttga tgaacttggt tacaaatcgc caagaggttt
     6241 agaacactgg aatgatacaa cagttctagg aataataaag aatgaaaaat ataaaggtga
     6301 tattctaatg ggaaaaactt ttacagttga cccaataagc aagagacggt tgagtaattt
     6361 tggagaagaa gataagtact atatcaagga taatcatgaa ccaataatat ctaaagaaga
     6421 ttttgaaaaa gctcaggaga ttagattgcg tcgagcagga aataagaaga cagctgcgaa
     6481 tgtaaatggg aagcgtgaac gctattcaaa aatgtatgct tttagtagca tgttggaatg
     6541 tggtttttgt ggttcaatat tatctagaag aagttggcac tgccgttcag attatcgcaa
     6601 agttgtgtgg cactgtgtta catcgataaa gaaaggaaag aaattttgta agcatagtaa
     6661 aggattagaa gagatcgcca ttgagggggc tttcctggaa gcttacagac aagtctatca
     6721 ttcaaatgaa aatttaatga cagacttact tgaaacgata gaatctgaat tgaatgacaa
     6781 tagccttaac aaggaactaa aaaggattac aaacaaactt cgaatattac taaaaaaaga
     6841 ggagaatctt gtaaatctaa ggctcgaagg aaaagttagc gattccatat acaatgaaaa
     6901 gtacaatgaa atttcctcag aaaaagagtt tctagcagaa gagaaggtaa atattgaaac
     6961 aacattaaaa tcagaaatcg atgtaaagaa aagactaact gagtttaagc acttgctatc
     7021 ttcgcaaaaa atgcttacgg agtttgatcg tgcagttttt gaaagtattg ttgagaaaat
     7081 tattgtaggt ggagttaata gcaacggaga aattgatcct gcaatgttaa ccataatatt
     7141 caaaacaggt gaaattcaaa acaaggatgg taaacaattt aaaagtaaac gtaaaaatgc
     7201 taaactagaa acagataaat tgtgtcctca aaacagtgac gaggataaaa aattgtattc
     7261 tcaaggaaca gacaacacac gtggagtgtg tagtgttgct ggttcgatct tagccagtca
     7321 ataaaatgat atgttttaaa aaaattataa tttcgaaacg tgaataaact tgtttaaact
     7381 ttatgtatct ttagaaagtg tgttaacttg aaagaacaaa tttttttgat gggtgggaat
     7441 cccccaataa agaaatatag tattgttgat aaaattgtat tatcaaccaa gattaaaaga
     7501 attatcattt ttacagtttt tcgagaaaat tgggaaccgt acatgaaaaa gtacacggaa
     7561 gtttttcaaa gtcaatttcc taatctaaac attgattact tgctcctgga cactgagcag
     7621 attgatcttg atagctatct agatgctgac ataattatca tcggtggtgg aaatacggaa
     7681 aaatatattg ctacttatat taatcaggag ttcaaaagtt atatcgatca tatgcttaat
     7741 aaagaggcaa aaattatagg attttctgca ggacccctac tattaggaga aaaagtctat
     7801 gtctcaccta atgataattc agatcatcag ataaagataa aaaatggatt aggactcttt
     7861 agtcagtttt taattagtgt ccattatgat tcctggaatg ataaagcaaa taaggataga
     7921 gctgaagaac tcgataatgt tcccataatt ccactaaatg atcattcttg tcttgtattg
     7981 gataaacttg gaaacatcat agagaaaatt gactaacttt cataatgtaa aaatggatct
     8041 aggaaataaa agtgtagacg aactggatag gttactagtg aaaactgcaa aaagtgttgt
     8101 aaagtgaatc ggagtgtgct tgatggattt tagtagtaag atagccataa ataaaggctg
     8161 gtcagatgat aaaaaatatt gtgtgacaga tcaaaatcag taaaaatatt tcttgcgtgt
     8221 ttctgataag tcgaagttag attataaaaa aatttgaatt tgatatgatg gagaaagtag
     8281 cttctcttgg agttccgatg tgtaaaccaa ttagcattga actctgcgat gacgaagtac
     8341 attctttaca cgaatggata gacggaagag atgcaataga tagcatttta acttattcag
     8401 aaaaccaaca atacacatat ggtgtagaag caggaaagat acttagaaag attcatacaa
     8461 ttcctgctac agaagtttgt gaagattggg aaatcttttt taatctaaaa attgatgata
     8521 aaatctccaa cgaaatgata tggtaagtcc gaaacgctca gtgtgtaagc ttgttgctaa
     8581 aagcgtaaaa accttggaac gaaaggaata atagacttcc tgcgaaacaa aaatacaata
     8641 caataaaact atggatgatg aagcaagtaa acaattaagc gatagccgtt tcaagagcct
     8701 tgtaggtgtt cagcgcacga gatgttagct gtgttaaaaa cagcttatca acgcaacgta
     8761 aacgcgcaaa aggtggacga aaaaccaaat taagcctaga cgatctcctc atggtaacta
     8821 ttcaatacat gcgagaatag cgcacttatg aacaaattgc ggctgatttt ggcattcacg
     8881 aaagcaactt aatccgtcgg agccaatggg ttgaagtaac tcttgttcaa aatggtttta
     8941 cgatttcaaa ttctgcccta attatgaaaa acagtaaaat tcgaaggatt gtaaggtaag
     9001 agtttttttc tttctgaaaa aatggtataa tagcaatcaa aactagaaaa taaaacggaa
     9061 tttggaacag atttgtctgt atcctagtag agtggtgatg ctatgaagat tagtaagagg
     9121 cacttattaa attattccat cttgattccc tacttgcttt tatctatttt gggcttgatt
     9181 gtggtctatt cgaccaccag tgctatttta attgaagaag gcaagagcgc cttgcagttg
     9241 gttcgaaacc aaggaatctt ttggattgtt agtttgatac tgattgcctt aatttataaa
     9301 ttgagactag attttttgag aaatgagcga ctaatcattt tagttatatt aatagaaatg
     9361 cttttattgt tcttggctcg ttttattggt atttccgtaa acggggcata cggttggatt
     9421 tcggttgcag gaataactat tcagccagct gagtacttaa aaatcattat tatttggtat
     9481 ttagctcacc gattctccaa acagcaagaa gaaatagcta cttatgattt tcaagttttg
     9541 actcaaaatc aatggcttcc ccgtgctttt aatgattggc gattcgttct cctagttctg
     9601 attggaagtt tgggaatttt ccctgattta ggaaatgcga ctattttagt cttggtttcc
     9661 ttgatgatgt atacagttag tggaatcgct tatcgctggt tttcaaccat tctggcgctc
     9721 gtatctgccg cttctgtctt tgtcttgacc actatcagcc taatcggtgt tgagaccttt
     9781 tcaaaaattc cagtatttgg ctatgtagcc aagcgcttta gtgccttttt taatcctttt
     9841 gccgatcgtg ctgatgcagg tcaccagtta gctaattctt attttgccat ggtcaatggc
     9901 ggttggtttg gtctaggtct tggaaactcg attgaaaaac gaggttattt gccagaagct
     9961 catacagact ttgtcttttc tatcgtgatt gaagaatttg gctttgttgg tgccagtctt
    10021 attttagctc tcttgttttt catgattttg cggattatct tggtcggtat ccgagcggag
    10081 aatcctttca atgccatggt tgcactcggt gtcggaggga tgatgttggt tcaggtattt
    10141 gtcaatatcg gagggatttc gggcttgatt ccatctacag gagtgacttt ccccttctta
    10201 tcccagggtg gaaatagtct tctagtctta tcagtggcag tagcctttgt cttaaatatt
    10261 gatgccagtg aaaaacgcgc taaattgtac cgagaattgg aaaatcaacc aatgaacctt
    10321 ctgttgaagt aggataaaga aaggatagtt tatgtctctt caaaaattag aaaattatag
    10381 taataaaagt gttgtgcaag aagaagtctt gattctaaca gaattactgg aagatattac
    10441 taaaaatatg cttgccccag agacctttga aaaaataata cagttgaaag aattatcaac
    10501 gcaggaagat tatcaaggtc taaaccgtct agtgactagc ttatcaaatg atgaaatggt
    10561 ctatatttca cgctatttct ctatcttgcc tcttttgatt aatatttcag aggatgtgga
    10621 tttagcttat gaaatcaatc atcaaaataa tattgatcag gactatttag gtaaattatc
    10681 tacaacgatt aaattggtag cagaaaagga aaatgccgtt gagatcctag aacacttgaa
    10741 tgttgtccct gttttgacag cccatccaac acaagtgcaa cgcaaaagta tgttggattt
    10801 aacaaatcat attcatagtc ttttgcgtaa ataccgtgat gttaagttgg ggttgatcaa
    10861 taaagataaa tggtacaatg atttgcgtcg ttacatcgaa attatcatgc agacagacat
    10921 gattcgtgag aaaaaattaa aagtgactaa cgaaatcacg aatgctatgg aatattataa
    10981 cagctccttt ttgaaagctg tacctcattt gacgacggag tataagcgct tagcgcaagc
    11041 gcatggtctg aatttaaaac aggctaaacc aatcaccatg ggtatgtgga taggtggtga
    11101 ccgtgatgga aatccatttg ttacagcaaa gaccttgaag cagtctgcac tcactcagtg
    11161 tgaagtcatc atgaactact atgataaaaa gatttaccaa ctttatcgtg aattttctct
    11221 ttcaactagc attgtcaacg tcagcaagca agtcagagaa atggctcgtc aatccaagga
    11281 taactcgatt taccgcgaaa aagagcttta ccgtcgtgcc ttgtttgata ttcaatcaaa
    11341 aattcaggca actaaaacct atctgattga ggatgaagaa gttgggactc gttatgaaac
    11401 cgccaatgat ttctacaagg atttgattgc cattcgagat tctctactag aaaataaggg
    11461 cgagtccttg atttcaggtg attttgtgga attattgcag gcagtagaga tatttggttt
    11521 ttacttagca tcaattgata tgcgacaaga ctctagcgtc tatgaagcct gtgtggcaga
    11581 actcttgaaa tcagcaggaa ttcattctcg ttatagcgag ttgagcgaag aagaaaagtg
    11641 tgaccttctc ttgaaagaat tagaagaaga tccccgaatt ctttctgcga ctcacgcaga
    11701 aaaatcagaa ttattagcaa aagaactagc tatttttaag acggctcgtg ttttgaaaga
    11761 taagttggga gatgatgtca tccgtcagac catcatttca catgcaacca gcctttctga
    11821 tatgctagaa ttagctattc tgttaaaaga agtaggactg gtggatacgg aaagggcgcg
    11881 tgttcagatt gttccccttt ttgaaacaat tgaagacttg gatcattcag aggaaacaat
    11941 gagaaaatat ctttctctta gccttgccaa aaaatggatt gactcacgaa ataactatca
    12001 agaaatcatg cttggctact ctgacagtaa taaagatggc ggttacttgt catcatgttg
    12061 gaccctctac aaggctcaac aacaattgac tgctattgga gatgaatttg gcgttaaggt
    12121 taccttcttc catggtcgtg gtggtactgt cggtcgtggt ggtgggccaa cctatgaagc
    12181 cattacatct caaccgctca agtctatcaa ggatcgtatc cgcttgacgg agcagggtga
    12241 agtaattggg aataaatacg gtaacaaaga cgccgcttac tataaccttg aaatgctagt
    12301 atcggcagct attaaccgta tgattactca gaagaagagc gataccaata ccccaaatcg
    12361 ttatgaagcc attatggatc aagtagtgga ccgtagttac gatatctacc gtgatttggt
    12421 ctttggtaat gagcatttct atgattattt cttcgagtca agtccaatca aggctatttc
    12481 aagttttaat attggttctc gtccagccgc tcgtaagact attactgaaa tcggtggatt
    12541 gcgtgctatc ccttgggtat tctcatggtc acagagtcgt gttatgttcc ctggatggta
    12601 cggggttggt tcaagcttca aggaatttat caataaaaat ccagagaata ttgctatctt
    12661 acgagatatg taccaaaatt ggcctttctt ccaatcgctt ctttcaaatg ttgatatggt
    12721 tttgtcaaaa tcaaatatga atattgcttt tgaatatgct aaactttgtg aagacgagca
    12781 agttaaggcc atctatgaga ctattttaaa tgaatggcaa gttactaaga acgttatctt
    12841 ggctattgaa ggacatgacg aactcttagc tgacaatcca tatctaaaag ctagtctgga
    12901 ttaccgtatg ccttacttta atattctcaa ctatattcag ttagagttga ttaaacgcca
    12961 acgtcgtgga gaattgtcca gtgatcaaga acgattgatt catatcacca tcaacggaat
    13021 tgcgacagga ttgcgtaatt caggttgata attttcaaga gtgaatgcta aaagtgaata
    13081 tcaaaaaaat tctaatagac tattgacaag tagtttaaaa atgatataat ttaaccattc
    13141 agaaaagtaa tcatacaaac tttttagaga gtctgtggta gctgaaaaca gataagtggc
    13201 aatgatgaaa attgggctga atgctattta gaatttgaaa ttataaaaat tcggtaagca
    13261 caccttacag tgcatctcgt tattgcgaga ctgagcgata gggaaattcc ctataattga
    13321 ggtggtaccg cgcatcgacg tcctcacaca agttttttgt gtgaggattt ttttgatgga
    13381 ggttagtata gaaagaaaac gatggcgtcg cttgtttaga taagtgaaat atgttaaagg
    13441 aaataaaaag gagaaacaga atgaaaaata aacgtttaat tggaattatt gctgcattag
    13501 cagtcttagt agcaggaagc ttgatttatt cttcaatgaa taaatcagaa gctcagaata
    13561 ataaggatga gaagaaaata accaagattg gtgtgcttca atttgtgagc catccatccc
    13621 ttgatttgat ttataaaggg atccaagatg gacttgcaga agaaggatat aaagatgatc
    13681 aagttaaaat tgattttatg aactcagaag gtgaccaaag taaggttgcg acaatgagta
    13741 aacaattggt tgcaaatggg aatgaccttg tggttggtat cgcaacacca gcagcccaag
    13801 ggttggctag tgcaacaaaa gacctaccgg ttatcatggc cgctattaca gacccaattg
    13861 gtgctaactt ggttaaagat ttgaaaaaac caggtggcaa cattacaggg gtatctgacc
    13921 acaatccagc tcaacaacaa gttgaactca tcaaggctct gacaccgaat gtgaaaacaa
    13981 tcggagctct ttactcaagt agcgaagaca attcaaaaac acaggtcgaa gaatttaagg
    14041 cttatgctga aaaagcaggt ctgacagtgg aaacatttgc agttccttca acaaatgaaa
    14101 ttgcctcaac tgtcactgtt atgactagca aggtagatgc tatttgggtt ccaattgata
    14161 acaccattgc atcaggattt ccaacggttg tctctagcaa tcaaagttct aagaaaccaa
    14221 tttatcccag tgcgacagct atggtagaag taggtggttt ggcatcagtt gtaattgacc
    14281 aacatgacct tggtgtggca acaggtaaaa tgattgtgca agtcttgaaa ggtgcaaaac
    14341 cagccgatac cccagtcaat gtcttttcaa ctggtaagtc agtcatcaat aaaaaaatag
    14401 cacaagaact aggtattact attcctgagt ttgttctcaa agaagcagga caagtcatcg
    14461 aataaataag gtagggagga ggagactctt cccatttttt aaaaagatga atatagaaag
    14521 gattaaataa aatatgattg tttccattat ttctcaagga tttgtctggg ctattctagg
    14581 tctgggaatc tttatgacat ttaggatttt aaactttcca gatatgacga cagaaggttc
    14641 cttccctctt gggggagctg ttgctgtcac tttgataacc aaaggcgtga acccattttt
    14701 agcgacactt gttgctgtag gagcaggttg tttggctgga atggcagcag gccttcttta
    14761 tacaaaaggg aagatcccaa ccttgctctc agggattttg gtgatgactt cttgtcactc
    14821 aatcatgctc ttgattatgg gacgtgcaaa tttaggcctg cttggaacca agcaaattca
    14881 ggatgttttg ccttttgatt cggatttgaa tcaactcttg acaggtctca tctttgtgag
    14941 tattgttatt gctctcatgc tctttttctt ggacactaaa ctcggacaag cctatattgc
    15001 tacaggggat aatcctgata tggctagaag tttcgggatt catactggac acatggagct
    15061 catgggcttg gtcttatcaa atggtgtgat tgcccttgca ggtgccctca ttgctcagca
    15121 agaaggttat gccgatgtgt ctcgagggat cggggttatc gttgtggggc ttgcaagttt
    15181 gattattgga gaagttattt tcaagagttt gagcttggca gagcgtttgg ttactatcgt
    15241 tgtaggttct atcgcttatc aatttttagt gtgggcagtt atcgcacttg gctttaatac
    15301 aagttacctt cgtttataca gtgccttgat tttagcagtc tgcctcatga ttccaacatt
    15361 taagcaaaca atcttgaaag gagccaagtt aagcaaatga cagcaattgt agaattaaaa
    15421 aatgcaacca aaatcgttaa aaatggcttt gatgaagaaa agattatttt aaatgatgtt
    15481 tccttagaaa tttttgaaca ggactttatc acgattttgg gtggaaatgg tgctggtaaa
    15541 tcaaccctct ttaacactat tgcaggaacc atatcactaa ccagtggaac tatccgtatt
    15601 ttaggtgagg atgttaccaa gttttcacca gagaagcgcg ctaagtatct gtctcgagtc
    15661 ttccaagatc caaagatggg gacagctcct cgtatgacag tggcagagaa tctcctgatt
    15721 gccaagtttc gtggtgaaaa gcgtggacta tttccgagac gtctggctag ctataaggat
    15781 aagtttcagg cgaccattga aaaagtggga aacggtcttg agaaacactt gaatacaccg
    15841 attgagttct tatctggtgg acaaagacag gctttgagtc tcttgatggc aaccttgaag
    15901 cgacctgaat tactcttgtt agacgagcat actgctgccc tggatccaaa gactagtgtt
    15961 gctttgatgg aattgacaga tgaatttgtt aagaaagatc aattgacagc ccttatgatt
    16021 acccatcata tggaagatgc tctcaaatat ggcaatcgct tgattgtcat gaaagaagga
    16081 cgggttatcc aagatttgaa acaagaagaa aaagcaaaaa tgaaaatctc tgattattat
    16141 caactctttg aataaagtag ggaaaatgag tgaaatggtt tacttttttt ctgaaataaa
    16201 gtatactata taaagtaaac tatgataaca tggaggtatt gtgtatggtt gacaaacaag
    16261 tcattgaaga aatcaaaaac aatgccaaca ttgtggaagt cataggagat gtgatttctt
    16321 tacaaaaggc aggacggaac tatctagggc tctgtccttt tcatggtgaa aaaacacctt
    16381 ctttcaacgt tgtagaggac aagcagtttt accactgttt tggttgtggt cgctcaggtg
    16441 atgtctttaa attcatcgag gagtaccaag gggttacctt tatggaggct gtccaaatct
    16501 taggtcagcg tgtcgggatt gaggttgaaa aaccgcttta tagtgaacag aagccagcct
    16561 cgccttacca agctctttat gatatgcacg aagatgcggc taaattttac catgctattc
    16621 tcatgacaac gactatgggc gaagaggcca gaaattacct ttatcagcgg ggtttgacag
    16681 atgaagtgct taaacatttt tggattggtt tagcacctcc agaacgaaac tatctctatc
    16741 aacgtttgtc tgatcagtat cgtgaagagg atttactgga ttcaggcctg ttttatctct
    16801 cggatgccaa tcaatttgta gacacctttc acaatcgcat tatgtttccc ctgacaaatg
    16861 accaaggaaa ggtcattgcc ttctcaggtc gtatctggca aaaaacggat tcacaaactt
    16921 ctaagtataa aaacagccga tcgactgcaa tttttaacaa aagttacgaa ttatatcata
    16981 tggatagggc aaaaaaatct tctggaaaag ctagtgagat ttacctgatg gaaggattca
    17041 tggatgttat tgcagcctat cgggttggaa tcgaaaatgc tgtggcgtcg atgggaacgg
    17101 ccttgagtcg agagcatgtt gagcatctga aaaggttaac caagaaattg gttcttgttt
    17161 acgatggaga taaggctggg caagccgcga tattgaaagc attggatgaa attggtgata
    17221 tgcctgtgca aatcgtcagc atgcctgata acttggatcc tgatgagtat ctacaaaaaa
    17281 atggtccaga agacttggcc tatctattaa cgaaaactcg tattagtccg attgagttct
    17341 acattcatca gtacaaacct gaaaacagtg aaaatctgca ggctcagatt gagtttattg
    17401 aaaaaatagc tcccttgatt gttaaagaaa agtccatcgc tgctcaaaac agctatattc
    17461 atattttagc tgacagtctg gcgtcctttg attatgccca gattgagcag attgttaatg
    17521 agagtcgtca ggtgcaaagg cagaatcgca tggaaagaat ttccagaccg acgccaatca
    17581 ccatgcctgt caccaagcag ttatcggcta ttatgagggc agaagcccat ctactctatc
    17641 ggatgatgga atcccctctt gttttgaacg attaccgttt gcgagaagac tttgcatttg
    17701 ctacacctga atttcaggtc ttatatgact tgcttggcca gtatggaaat cttcctccag
    17761 aagttttagc agagcagaca gaggaagttg aaagagcttg gtaccaagtt ttagctcagg
    17821 atttgcctgc tgagatatcg ccgcaggaac ttagtgaagt agagatgact cgaaacaagg
    17881 ctctcttgaa tcaggacaat atgagaatca aaaagaaggt gcaggaagct agccatgtag
    17941 gagatacaga tacagcccta gaagaattgg aacgtttaat ttcccaaaag agaagaatgg
    18001 agtaataatg gcaacaaaac aaaaagaagt aacaacattt gacgtacagg tagcagaatt
    18061 tatccgtaat cataagcaaa aagggacagc aacagatgat gaaatcaatg caagtctggt
    18121 tattcctttt accttggacg ctgatgggat tgaagatctc ttgcaacgga ttcaggatgc
    18181 aggcatttct atcacagata acgaaggaaa tccaagtgcg cgtgttctta gcaatgaaga
    18241 agaaccagaa ctcagcgatg aggacttgat tgggtcaact tctgctaagg tcaatgaccc
    18301 tgtccgtatg tacttgaaag aaataggggt cgttcctctc ttgaccaatg aagaggagaa
    18361 agagttggca ctggctgttg aagctggcga tatcgaagcc aaacaacgtc ttgcggaagc
    18421 caatcttcgt ttggttgttt ccattgccaa acgctatgtc ggtcgtggca tgcagttcct
    18481 tgacttgatt caagaaggaa atatgggctt gatgaaggcg gttgacaagt ttgactattc
    18541 taaagggttc aagttttcaa cttatgcaac ttggtggatt cgtcaggcta tcactcgtgc
    18601 tattgcggac caagctcgta ccatccgtat cccagttcac atggttgaaa ctatcaataa
    18661 attggttcgt gaacagcgga atctccttca agaattgggg caagatccga caccagaaca
    18721 gattgctgaa cgaatggata tgacacctga taaggttcgt gaaatcttga agattgccca
    18781 agaaccagta tctcttgaaa ctcctatcgg tgaagaggac gatagccacc ttggagactt
    18841 tatcgaagat gaagtgattg aaaatccagt ggattatacg actcgtatcg tcttgcgtga
    18901 gcaattggat gaaatcttag atactcttac agaccgtgaa gaaaatgttc tgcgtctacg
    18961 ttttggacta gatgatggaa aaatgcgcac acttgaagat gtggggaaag tctttaacgt
    19021 aactcgtgag cgtatccgtc agattgaagc aaaggctttg agaaaactac gccaaccaag
    19081 tcgcagcaaa ccgcttcgtg attttattga agactaagag tgaggaaaat atggcttata
    19141 cagaagagca aattgaaaac atcaaaacac ggattttaac agccttggaa gaagtcatcg
    19201 accctgagtt gggaatcgat attgtcaatc ttggtttgat ctatgagatt cgttttgacg
    19261 gtgacacagg gcaaacagag attgacatga ctttgacaac tatgggttgt cccttagcag
    19321 accttttgac agaccagatt tatgatgcta tgatagaggt tccagaagta acggatactg
    19381 aggttaaatt agtctggtat ccagcctgga cagttgaaaa aatgagtcgc tatgcccgca
    19441 ttgccctagg cattaagtaa acatataaaa gcatgtgaga gactgttgga aaagcgagga
    19501 aatttcccct cttttcctct agtctctcct ttcttttgct gattttattc aaagaaaatg
    19561 atataatagt agttatggag aaaaagaaat tacgcatcaa tatgttgagt tcaagtgaga
    19621 aagtagcagg acagggagtt tcaggtgctt accgtgaatt agttcgtctt cttcaccgtg
    19681 ctgccaagga ccaattgatt gttacagaaa atcttccgat cgaggcagat gtgactcact
    19741 ttcatacgat tgattttccc tattatttat caaccttcca aaagaaacgc tcagggagaa
    19801 agattggcta tgtgcatttc ttgccagcta cacttgaggg aagtttgaaa attccatttt
    19861 tcttaaaggg aattgtgaaa cgctatgtat tttcttttta caaccggatg gagcacttgg
    19921 ttgtggtcaa tcctatgttt attgaggatt tggtagcagc tggtattcca cgtgaaaaag
    19981 tgacctatat tcctaacttt gtcaacaagg aaaaatggca tcctctacca caagaagagg
    20041 tagtcagact gcgcacagat cttggtctta gtgacaatca gtttatcgta gtaggtgctg
    20101 ggcaagttca gaaacgtaaa gggattgatg actttatccg tctggctgag gaattgcctc
    20161 agattacctt tatctgggct ggtggcttct cttttggtgg tatgacagat ggttatgaac
    20221 actataagaa aattatggaa aatcccccta aaaatttgat ttttccaggc attgtatcgc
    20281 cagagcggat gcgcgaattg tatgctctag cggatctttt cttgttgcct agttacaatg
    20341 agctctttcc tatgactatt ttagaagctg cgagttgtga ggctcctatt atgttgcgtg
    20401 atttagatct ctataaggtg attttggagg gaaattatcg ggcgacagcg ggtagagaag
    20461 agatgaaaga ggctattttg gaatatcaag caaatcctgc tgccttaaaa gatctcaaag
    20521 aaaaggctaa gaatatttcc agagagtatt ctgaagagca tctgttacaa atctggttgg
    20581 acttttatga gaaacaagcc gctttaggga gaaagtaaaa agtgaggtaa tctatgcgaa
    20641 ttggtttatt tacagatacc tattttcctc aggtttctgg tgttgcgacc agtattcgaa
    20701 ccttgaaaac agaacttgaa aagcagggac atgctgtttt tatctttacg acgacagata
    20761 aggatgtcaa tcgctacgaa gattggcaaa ttatccgcat tccaagtgtt cctttctttg
    20821 cttttaagga tcgtcgcttt gcctaccgag gttttagcaa ggcacttgaa attgctaaac
    20881 agtatcagct agatattatc catactcaga cagaattttc tcttggcctg ttggggattt
    20941 ggattgcgcg tgaattgaaa attccagtca tccataccta tcacacccag tatgaagact
    21001 atgtccatta tattgctaag gggatgttga tccgaccgag tatggtcaag tatctggtta
    21061 gaggtttcct gcatgatgtg gatggggtta tttgccctag tgagattgtc cgtgacttgc
    21121 tatctgatta taaggtcaag gttgaaaaac gggtcattcc tactgggatt gaattagcca
    21181 agtttgagcg tccggaaatc aagcaggaaa atttgaaaga actgcgtagt aaactaggga
    21241 ttcaagatgg tgaaaagacg ttgcttagtc tttcgagaat ctcctatgaa aaaaatattc
    21301 aagcagtttt agtagccttt gctgatgttc tgaaagagga agacaaggtt aaactggtag
    21361 tagctgggga tggcccttat ctgaatgacc tcaaagagca agcccagaac ctagagattc
    21421 aagactcagt catctttaca gggatgattg ctcctagtga gacggctctt tactataaag
    21481 cggcggattt tttcatttcg gcatcgacaa gcgaaacgca aggtttgacc tacttggaaa
    21541 gcttagccag tggaacacct gtcattgctc acggaaatcc ttatttgaac aacctcatca
    21601 gtgataaaat gtttggaacc ttgtactatg gagaacatga tttggctggt gctattttgg
    21661 aagccctgat tgcaacacca gacatgaacg agcatacctt atcagagaaa ttgtatgaga
    21721 tttcagctga gaactttggg aaacgagtgc atgagtttta tctggatgcc attatttcaa
    21781 ataacttcca gaaagatttg gctaaagatg atacggtcag tcagcgtatc tttaagacag
    21841 ttttgtatct tcagcaacag gtggttgctg tacctgtaaa aggatctaga cgcatgttga
    21901 aggcttcaaa aacacagttg atcagtatga gagactattg gaaagaccat gaagaataga
    21961 aagaggaaca gctatgaaaa aaacaattaa tgagaagcgg tcgtgataaa aagattgcgg
    22021 gtgtttgtgc tggggtggcc cattatctgg atatggatcc gactatcgtt caagtcattt
    22081 ggggtgttct tacttgctgt tacggagctg gaattgtagc ttacattatt ttatggatta
    22141 tcgtaccagt agcaactgac tattgaaaac tagctcaatt catgctaaga taatagaaaa
    22201 tagaatgtaa cgaaggagag aaaaatggca tttggagata atggaaatcg taaaaaaact
    22261 atgtttgaga aaataacctt gtttatcgtg attatcatgc tagtagcaag tttattggga
    22321 atttttgcaa ctgcaattgg tgccctcagt aatctataaa atagattcaa gaaaatttag
    22381 tgactgggat ttcccagccc ttttttaaag tgagaagaaa taatgagtat gtttttagat
    22441 acagctaaga ttaaggtcaa ggctggtaat ggtggcgatg gtatggttgc ctttcgtcgt
    22501 gaaaaatatg tccctaatgg aggcccttgg ggtggtgatg gtggtcgtgg aggcaatgtg
    22561 gtcttcgttg tagacgaagg attacgtacc ttgatggatt tccgctacaa tcgtcatttc
    22621 aaggctgatt ctggtgaaaa agggatgacc aaagggatgc atggtcgtgg tgctgaggac
    22681 cttagagttc gagtaccaca aggtacgact gttcgtgatg cggagactgg caaggtttta
    22741 acagatttga ttgaacatgg gcaagaattt atcgttgccc acggtggtcg tggtggacgt
    22801 ggaaatattc gtttcgcgac accaaaaaat cctgcaccgg aaatctctga aaatggagaa
    22861 ccaggtcagg aacgtgagtt acaattggaa ctaaaaatct tggcagatgt cggtttagta
    22921 ggattcccat ctgtagggaa gtcaacactt ttaagtgtta ttacctcagc taagcctaaa
    22981 attggtgcct accactttac cactattgta ccaaatttag gtatggttcg cacccaatca
    23041 ggtgaatcct ttgcagtagc cgacttgcca ggtttgattg aaggggctag tcaaggtgtt
    23101 ggtttgggaa ctcagtttct ccgtcacatc gagcgtacac gtgttatcct tcacatcatt
    23161 gatatgtcag ctagcgaagg ccgtgatcca tatgaggatt acctagctat caataaagag
    23221 ctggagtctt acaatcttcg cctcatggag cgtccacaga ttattgtagc taataagatg
    23281 gatatgcctg agagtcagga aaatcttgaa gaatttaaga aaaaattgtc tgaaaattat
    23341 gatgaatttg aagagttacc agctatcttc ccaatttctg gattgaccaa gcaaggtctg
    23401 gcaacacttt tagatgctac agctgaattg ttagacaaga caccagaatt tttgctctac
    23461 gacgagtccg atatggaaga agaagcttac tatggatttg acgaagaaga aaaagccttt
    23521 gaaattagtc gtgatgacga tgcgacatgg gtactttctg gtgaaaaact catgaaactc
    23581 tttaatatga ccaactttga tcgtgatgaa tctgtcatga aatttgcccg tcagcttcgt
    23641 ggtatggggg ttgatgaagc ccttcgtgcg cgtggagcta aagatgggga tttggtccgc
    23701 attggtaaat ttgagtttga atttgtagac taggagactg gtatgggaga taaaccgata
    23761 tctttccgag atgcggatgg taattttgtt tccgccgcag acgtttggaa tgaaaagaaa
    23821 ttggaagaac tatttaatcg tctcaatcca aatcgtgcct tgagattggc acgaactaaa
    23881 aaggaaaatc catctcagta aagaagctaa aaaatcccgg ctctttgtca actgtagtgg
    23941 gttgaagaaa agctaagctc gagaaaggac aaattttgtc ctttcttttt tgatattcag
    24001 agcgatgaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg cattgcgctt
    24061 gataagtttg atgagattat tggtcgcttc cagtttggca ttagaatagt gtagttgaag
    24121 ggcgttgaca atcttttctt tatctttgag gaaggtttta aagacagtct gaaaaatagg
    24181 atgaacctgc ttaagattgt cctcaataag tccgaaaagt ttctctggtt ccttattctg
    24241 gaagtgaaaa agcaagagct gatagagctg atagtgatgt ttcaagtctt ccgaatagct
    24301 caaaagcttg tttaaaatct ctttattggt taaatgcata cgaaaagtag gacgataaaa
    24361 acgtttatca ctcagtttac ggctatcctg ttgaatgagt ttccagtagc gcttgatagc
    24421 cttgtattca tgggattttc gatgaaactg attcatgatt tggacacgca cacgactcat
    24481 agcacggcta agatgttgta caatgtgaaa gcgatcaaga acgattttag cattcgggag
    24541 tgaaacagtc tgggagactg tttcagcctg agcctagaaa tttgaaagcg aagctgttta
    24601 gccaagccat agtaagggct aaacatatcc atggtaatga ttttgacgcg acatcggacg
    24661 gctctatcat atttaagaaa gtgatctcgg atgacagctt gtgttctgcc ttcaagaaca
    24721 gtgatgatat tgagattgtt aaaatcttgc gcaataaagc tcatctccat ctcccgattg
    24781 aaacagtcac tccccggact gtttcaacgt cccaggacat aatctcagga agacaagaaa
    24841 aatcatgttt aaagtgaaaa tcattgagct tacgaataac agttgaagtt gaaatggcca
    24901 gctgatgagc aatatcggtc atagaaatct tctcaatcaa cttttgcgca attttttggt
    24961 tgataatacg aggaatttgg tgatttttct tgacgataga agtttcagcg accatcattt
    25021 ttgaacagtg atagcacttg aatcgacgct ttctaaggag aattctagta ggcataccag
    25081 ttgtctcaag gtaaggaatc ttagacggtt tttgaaagtc atatttcttc aattggtttc
    25141 cgcactcagg gcaagatggt gcgtcgtagt ccagtttggc gatgatttcc ttgtgtgtat
    25201 ctttattgat gatgtctaaa atctggatat tagggtcttt aatgtctagt aattttgtga
    25261 taaaatgtaa ttgtcccata tgaatctttc taatgagttg ttttgtcgct tttcattata
    25321 gatcttatgg gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac
    25381 agcatatctt ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat
    25441 tcttatttca atttgttata gtatatctga tgtcaaagtt ctcggcgaat caaatagcga
    25501 ttcccaagcc tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta
    25561 agtctgacgc tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga
    25621 acaggaacgt gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca
    25681 aaaaggtagt cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt
    25741 ttctattttc actgtaacct tttaacgtcc tcatatcttg tatacacgag gaaagatgta
    25801 cgacttatcc cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga
    25861 gtcacggtta tctttaaaat agattgtctg ataggatgct agcctgaaaa cgtcttgttc
    25921 atgaaatata ggacggtatg tataaaacgc ttctgtgaac tgagagaagg gggagaagtt
    25981 cttgctaaaa tttagttgaa cagccgtatt ccgatattta gataagagat ctagtcttag
    26041 ctcctactcg gtttcagggg ataaaaaagg ggcaatagcg attcgagaaa gattatactc
    26101 ttcgaaaatc tcttcaaatc acgtcaatat cgccttgccg tacgtgtagg atactgacta
    26161 cgtcagttcc atctacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag
    26221 tgtgatcttt gatttttatt gagtattagt aattcagtta ctaactcgtc aactctgatt
    26281 tatccaataa aattgaaaag gatggaaaaa aggataaatt tatgatatac tttattttga
    26341 agaccttatt agaaatcttg aaagagtatt gaaaacttag aatgagaaaa attgttatca
    26401 atggtggatt accactgcaa ggtgaaatta ctattagtgg tgctaaaaat agtgttgtgg
    26461 ccttaattcc agctattata ttggctgatg atgtggtgac tttggattgt gttccagata
    26521 tttcggatgt agccagtctt gtcgaaatca tggaattgat gggagctact gttaagcgtt
    26581 atgacgatgt cttggagatt gatccaagag gtgttcaaaa tattccaatg ccttatggta
    26641 aaattaacag tcttcgtgca tcttattatt tttatgggag cctcttaggc cgttttggtg
    26701 aagcgacagt tggtctaccg ggaggatgtg atcttggtcc tcgtccgatt gacttacacc
    26761 ttaaggcgtt tgaagctatg ggtgccactg ctagctacga gggagataac atgaagttat
    26821 ctgctaaaga tacaggactt catggtgcaa gtatttacat ggatacggtt agtgtgggag
    26881 caacgattaa tacgatgatt gctgcggtta aagcaaatgg tcgtactatt attgaaaatg
    26941 cagcccgtga acctgagatt attgatgtag ctactctctt gaataatatg ggtgcccata
    27001 tccgtggggc aggaactaat atcatcatta ttgatggtgt tgaaagatta catgggacac
    27061 gtcatcaggt gattccagac cgcattgaag ctggaacata tatatcttta gctgctgcag
    27121 ttggtaaagg aattcgtata aataatgttc tttacgaaca cctggaaggg tttattgcta
    27181 agttggaaga aatgggagtg agaatgactg tatctgaaga cagcattttt gtcgaggaac
    27241 agtctaattt gaaagcaatc aatattaaga cagctcctta cccaggcttt gcaactgatt
    27301 tgcaacaacc gcttacccct cttttactaa gagcgaatgg tcgtggtaca attgtcgata
    27361 cgatttacga aaaacgtgta aatcatgttt ttgaactagc aaagatggat gcggatattt
    27421 cgacaacaaa tggtcatatt ttgtacacgg gtggacgtga tttacgtggg gccagtgtta
    27481 aagcgaccga cttaagagct ggggctgcac tagtcattgc tgggcttatg gctgaaggta
    27541 aaactgaaat taccaatatc gagtttatct tacgtggtta ttctgatatt atcgaaaaat
    27601 tacgtaattt aggagcggat attagacttg ttgaggatta aaccgtagag gtgtttatga
    27661 atatttggac caaattagca atgttttctt tttttgaaac ggatcgcttg tatttgcgtc
    27721 ctttcttttt tagtgatagt caggacttcc gcgagatagc ttcaaatcca gaaaatcttc
    27781 aatttatttt cccaacgcag gcaagtctgg aagaaagtca atatgcactg gccaattact
    27841 ttatgaagtc ccctttggga gtgtgggcaa tttgtgacca gaaaaatcaa caaatgattg
    27901 gttctattaa atttgagaag ttagatgaaa tcaaaaaaga agctgagctt ggctattttt
    27961 tgagaaaaga tgcttggtcg caaggattta tgacagaggt tgttagaaaa atttgtcagc
    28021 tttcttttga ggaatttggc ttaaaacaat tatctatcat tacccacctt gaaaatgaag
    28081 ctagccaaag agttgctctt aagtctggat ttagtttgtt ccgtcagttt aagggaagtg
    28141 atcgttacac aagaaaaatg cgggattatc ttgaatttcg gtatgtaaaa ggagagttca
    28201 atgagtaagc atcaggaaat tctaagctat ttggaggaat taccagtagg taaaagggtc
    28261 agtgttcgta gcatttcgaa tcatctagga gttagtgatg gaacagccta tcgggctatt
    28321 aaagaagctg aaaaccgtgg aattgtggag acccgtccta gaagtggaac aattcgtgtt
    28381 aaatcccaga aagttgctat agagagatta acgtttgctg aaattgcaga agtgacttct
    28441 tctgaggttc tggctgggca agaaggttta gagagagaat ttagtaagtt ttcaattggt
    28501 gccatgactg aacaaaatat cttgtcttac cttcatgatg gggggctctt gattgtcgga
    28561 gaccgaaccc gtattcagtt gctagccttg gaaaatgaaa atgcagttct ggttacaggg
    28621 ggatttcagg ttcatgatga tgtgcttaaa ctggccaatc aaaaagggat tcctgttcta
    28681 agaagtaagc atgatacctt taccgtcgcg accatgatca ataaagcctt gtcaaatgtc
    28741 caaatcaaga ctgatattct gacagttgag aaactttatc gccctagtca tgagtatggt
    28801 tttctgagag agacagatac agttaaagat tatttggact tggttcgtaa gaatcgtagc
    28861 agccgtttcc ctgttatcaa tcaacatcag gtcgttgttg gcgttgtaac catgagagac
    28921 gctggtgata aatcaccaag cacgacaatt gataaggtta tgtctcgtag tctatttttg
    28981 gttggattat cgacaaatat tgccaatgtg agtcaacgga tgatcgcaga agactttgaa
    29041 atggtaccag ttgttcgaag caatcaaact ttgcttggcg ttgtgacgcg acgagatgtc
    29101 atggagaaga tgagccgttc ccaagtttcg gctctaccaa ctttttctga gcagattgga
    29161 caaaagctct cttatcacca tgatgaagta gtcattacag tggaaccctt tatgctagaa
    29221 aaaaatggag ttttggctaa tggtgtattg gcagaaattc tgacccacat gacccaagat
    29281 ttagttgtta atagtggtcg caatctcatt atcgagcaga tgctgatcta ctttttgcag
    29341 gctgttcaga tagatgatat attgcgcatt caggcacgga ttattcatca tacgagacgg
    29401 tcagctataa ttgattacga tatttatcat ggtcaccaga ttgtttcaaa agcaaatgtg
    29461 actgttaaaa ttaattagaa actaggagaa aagatgataa cattaaaatc agctcgtgaa
    29521 atcgaagcta tggacaaggc tggtgatttt ctagcaagta ttcatatagg cttacgtgat
    29581 ttgattaagc caggcgtaga tatgtgggaa gttgaagaat atgtccgccg tcgttgtaaa
    29641 gaagaaaatt tccttccact tcagattggg gttgacggtg ccatgatgga ctatccttat
    29701 gctacctgtt gctctcttaa cgatgaagtg gctcacgctt tccctcgtca ttatatcttg
    29761 aaagatggtg atttgctcaa agttgatatg gttttgggag gtcccattgc taaatctgac
    29821 ctgaatgtct caaaattaaa cttcaacaat gttgaacaaa tgaaaaaata cactcagagc
    29881 tattctggtg gtttagcaga ctcatgttgg gcttatgctg ttggtacacc gtccgaagaa
    29941 gtcaaaaact tgatggatgt aaccaaagaa gctatgtaca agggtattga gcaagctgtt
    30001 attggaaatc gtatcggtga tatcggtgcg gctattcaag aatacgctga aagtcgtggt
    30061 tacggtgtag tgcgtgattt ggttggtcat ggtgttggcc caactatgca cgaagaacca
    30121 atggttccta actatggtat tgcaggtcgt ggactccgtc ttcgtgaagg aatggtctta
    30181 accattgaac caatgatcaa tacaggcgat tgggaaattg atacagatat gaaaactggt
    30241 tgggcgcata agaccattga cggtggattg tcatgtcagt atgaacacca atttgtcatt
    30301 acgaaagatg gacctgttat cttgactagc caaggtgaag aaggaactta ttaataaaaa
    30361 gtgaaaagac tactggaagt ttattatgaa aaaatccagt agatcttttc ataataaaac
    30421 gcattgtatc aagtgttagg ggctgatatc atgcgttttt ctgcttttaa gattttttcc
    30481 aactctgttt gtaagcgcat cataacaaag ggtctaggat tcagggctct cctcctatat
    30541 actattagta aagtaaaact aagggaggat attttagtgt cgcagtctat tgttcctgta
    30601 gagattccac aatattgtcg ttttgattct aaaaagagaa atggaattct gtttaatgtt
    30661 cgtattgcca atcttaaatt tacctttttt agattagact tcctgcgaaa caaaatatgg
    30721 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
    30781 cttgttggtg ttcagcgtac cacttttgaa gagatgttag ctgtattaaa aacagcttat
    30841 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ccttcttatg
    30901 gccactcttc aatatgtgcg agaatatcga acttatgaac aaattgcggc tgattttggt
    30961 attcacgaaa gcaacttact ccgtcggagc caatgggttg aagtaactct tgttcaaagt
    31021 ggttttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
    31081 gaagtaaaaa tcaatcgccc taaaaaaaga attagcgaat gattctggta aaaagaaatg
    31141 ccacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat
    31201 cgctgtgaac tattgtcatg atatgaagtt gttcaaaatg agtcgcagaa atatcggaca
    31261 agctggaaaa atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagc
    31321 acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gttgaagata aagcctataa
    31381 ccatgcgcta tccaaggata gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt
    31441 taaaatgatt tcaacaactt atcgaaatca tcgtaaacgt ttcggattac gaatgaattt
    31501 gagtgctggt attatcaatc atgaactagg attctagttt tgcaggaagt ctattgaggt
    31561 attgagctag tttatgaaaa aattgggtga aaaagtcgag tgttttagaa acccacagtg
    31621 tagtattcta gtttcaatcc actatatttt gctactcccc gtaaagtttc tattttccct
    31681 gatttctgat ataatagaaa tattgacttc aagagtaagg aagagaagat gaacgcatta
    31741 ttaaatggaa tgaatgaccg tcaggctgag gcggtgcaaa cgacagaagg tcccttgcta
    31801 atcatggcag gggctggttc tggaaagact cgtgttttga cccaccgtat cgcttatttg
    31861 attgatgaaa agctggtcaa tccttggaat atcttggcca ttacctttac caacaaggct
    31921 gcgcgtgaga tgaaagagcg tgcttatagc ctcaatccag cgactcagga ctgtctgatt
    31981 gcgaccttcc actccatgtg tgtgcgtatt ttgcgtcgcg atgcggacca tattggctac
    32041 aatcgtaatt ttacaattgt ggatcctggt gaacagcgaa cgctcatgaa acgtattctc
    32101 aaacagttga acttggatcc taaaaaatgg aatgaacgaa ctattttggg gaccatttcc
    32161 aatgctaaga atgatttgat tgatgatgtt gcttatgctg cccaagctgg cgatatgtat
    32221 acgcaaattg tggcccagtg ttatacagcc tatcaaaaag aacttcgtca gtctgaatcc
    32281 gttgactttg atgatttgat tatgctgacc ttgcgtctct ttgatcaaaa tcctgatgtt
    32341 ttgacctact accagcaaaa attccaatac atccacgttg atgagtacca agataccaac
    32401 cacgctcagt accaattggt caaactcttg gcttcccgtt ttaaaaatat ctgtgtggtt
    32461 ggggatgcgg accagtctat ctacggttgg cgtggtgctg atatgcagaa tatcttggac
    32521 tttgaaaagg attaccccaa agccaaggtt gttttgttgg aggaaaatta ccgctcaacc
    32581 aaaaccattc tccaagcggc caacgaggtt attaaaaata ataaaaatcg ccgtcctaaa
    32641 aatctctgga ctcaaaacgc tgatggggag caaatcgttt actatcgtgc cgatgatgag
    32701 ctggatgagg ctgtatttgt agccagaacc atcgatgaac ttagtcgcag tcaaaacttc
    32761 cttcataagg attttgcagt tctctatcgg actaatgccc agtcccgtac aattgaggaa
    32821 gccctgctca agtctaacat tccttatacc atggttggcg gaaccaaatt ctacagccgt
    32881 aaggaaattc gcgatattat tgcttatctc aaccttattg ctaatttgag tgacaatatt
    32941 agttttgagc gtattatcaa cgagcctaaa cgtggaattg gtctaggtac agttgagaaa
    33001 atccgtgatt ttgcaaattt gcaaaatatg tctatgctgg atgcttctgc taatattatg
    33061 ttgtctggta tcaagggtaa ggcagcccaa tctatctggg attttgccaa tatgatgctt
    33121 gatttgcggg agcagctaga ccacttaagc attacagagt tggttgagtc cgtcctagaa
    33181 aaaacaggtt atgtcgatat tcttaacgcc caagcgactc tagaaagcaa ggcacgggtt
    33241 gaaaatatcg aagagtttct ttctgttacg aagaactttg atgacaccac tgatgtgaca
    33301 gaagaggaaa ctggtctgga caaactgagt cgtttcttaa atgacttggc tttgattgcc
    33361 gacacagatt caggtagtca ggagacatca gaagtgacct tgatgaccct gcatgctgcc
    33421 aaaggtctcg aatttccagt tgtctttttg attgggatgg aagaaaatgt ctttccactt
    33481 agtcgtgcga ctgaagatcc agatgaatta gaagaagagc gccgtctagc ctatgtaggt
    33541 atcacgcgtg cagagaaaat tctctatctg accaatgcca actcacgctt gctttttggt
    33601 cgtaccaatt ataaccgtcc gactcgtttt attaacgaaa tcagttcaga cttgcttgag
    33661 tatcaaggtc tggctcgtcc tgcaaataca agctttaagg catcatatag cagtggtagt
    33721 atttcctttg gtcaaggtat gagtttggct caggctcttc aagaccgtaa acgcggtgct
    33781 gccccaaaat caatccagtc aagcggtctt ccatttggtc aatttacagc tggcgcaaaa
    33841 tcagcatcta gcgaggcaaa ttggtccatt ggtgacattg ctctccacaa gaaatgggga
    33901 gagggaactg ttctggaagt ttcaggtagc ggtgctaggc aggaattgaa aatcaatttc
    33961 ccagaagtag gtttgaaaaa acttttagcc agtgtggctc caattgagaa aaaaatctaa
    34021 ttttccatcc ttctcacgaa taataaagtg aggaggattt ttatgtacag tatttcattc
    34081 caagaagatt cactattacc aagagaaagg ctggccaagg aaggagttga agcgcttagt
    34141 aaccaagagt tgctagctat tttactcagg acaggaacac gtcaagctag cgtttttgaa
    34201 attgcccaaa aagtcttgaa caatctttca agcctaacgg atttgaaaaa aatgaccctg
    34261 caggaattgc agagtttgtc tggtattggg cgtgttaagg ccatagaatt acaagctatg
    34321 attgaactgg ggcatcgtat tcacaaacac gagactcttg aaatggaaag tattctcagc
    34381 agtcaaaagt tggccaagaa gatgcagcag gaattagggg ataaaaaaca agagcacctg
    34441 gtggcactct atctcaatac tcaaaatcaa atcatccatc agcagaccat ttttatcggt
    34501 tctgtaactc gtagtatcgc tgaaccgcga gagattctgc actatgcaat caagcatatg
    34561 gcgacttctc ttatcttggt ccacaatcat ccttcaggag cggtagcgcc tagccaaaat
    34621 gatgatcatg tcactaaact tgttaaagaa gcctgcgaat tgatggggat tgttctcttg
    34681 gaccatttga ttgtctctca ttctaattac tttagttatc gtgaaaagac agatttaatc
    34741 taaagttcat taacgacata gtcaaagagt tttttatctt tgggacgatt ttcaaaaaga
    34801 agttctggat gccattggac accgagaaag gcgacatcat ccgtactcat gacagcctca
    34861 atgataccat ctttaggatc atgagccaca acttttaaat ttggtgctaa gtccttgatg
    34921 ctctggtggt ggaaggagtt gatatgagag atttctccat agatttcttg gagaacggta
    34981 tctggttctg ttaccaagcg ttgagttgtg tactcaacag aagaatcctg ccaatggtct
    35041 tcgatatctt ggtacaaagt tccacccatg gcaacgttaa agagttgggt accacggcag
    35101 acagagaaaa tgggcttttt ctgtttaata gcttccttga tgagggtcag ttcgaagata
    35161 tctctttgaa ggtgatagtc atcgctatca atggttttgg gttcgccata aaattttgga
    35221 tcgacatttt gcccacctgt caagatgagc ttgtcaatca aactgatata gtggcaggcc
    35281 atttcttgat caccaatcgg taggatgatg ggaatccctc cagaatcttt aacgccttca
    35341 acaaagcctt ttgctgcgta gctcatcatg atgtcatcat ctggatgagc tttttcgttt
    35401 cctgtaatcc caataactgg ttttttcata aaatgatttt cgctttctaa tcctcttttc
    35461 gcatgaagta gaggagggtt tggagttcac ttgtcaaatc gacatactga acgaccacgt
    35521 cttttggtaa atgcagatgg actggtgaaa aactgagaat tcctttcaca ccagcatcaa
    35581 ccaagagatt agcaacctct tgtgacttga cgctgggaac agttaggata gcagtcttca
    35641 catcagcatc cttgatttta tccttgatct gagaaatccc gtaaatggga atcccgtcag
    35701 gagtttgggt accgacttca ggatggtcgt ctaggtcaaa ggccatgata atcttcatct
    35761 tgttacgttc gtggaagcgg tagtggagaa gggcatggcc catatttcca ataccaacca
    35821 gcatgacatt ggtaatagag ttgtcattga gcaaatcggc aaaaaatgtc attagttttt
    35881 tgacatcata gccaaaacca cgacgaccaa gttcaccaaa ataggaaaaa tcacgacgta
    35941 cggtcgctga atcaataccg atagcctctg caatttgctt agagttggca cgttcaatct
    36001 tttctgcatg aaatctctta aaaattcgat agtagagaga gagtcttttt gctgtagctt
    36061 ttggaatagc aaactgttta tctttcacaa aatcacaacc tttctattct tctattttat
    36121 agaaacattg tgaaaaaatc aacaaaaata agaaaaaact aagaaaaatc ttagttttga
    36181 tgtaaaaaat ctgcatgaga tagaaaacgg tagaggtctc cgaccagacc ctgataaact
    36241 ttttggcccc taaaagtcag agaagtcaca taaagtgtat ctggtaaggt tacacatcct
    36301 gacaaagtca acatgagagc ctcatgatcc tcatacttga gagtacgctc tacatgatag
    36361 cagtccttat aggtcagttc aaacattttg gctctatctt tccgattttg taaagacacc
    36421 acgttctacc aagctatcca tgaggaagta gaatttttcc tgatgaatat ggtggtcttc
    36481 tgatttgaaa atatcaacta gacgaaggcc aaacttgtca gtgatattga ttttagcccc
    36541 tgtaagttcc ttgttaatga tgattttgag ttggaagcct tcaccgctgt ttggcacttt
    36601 ttccaaaagg cgagtcagtt catagttacc aaccttagtt tcaaaaaagg tgttatcttt
    36661 gagggtgaat tttttaacag aagggctaag agtgtaatcg taacgacaat tttttaactg
    36721 aatgattttt tcaaatgcca tatggctaac ctccgataat ttcttttaag gtttttgcga
    36781 gggtttgtag gtcttcaacg gtattttgtg gcgacaaact gatgcgaagg gattccttca
    36841 agcgttctga atttgcgcca tacatggctt caagaacatg gctggattgg acaacgcctg
    36901 cagtacaggc tgagccagta gagattgaaa ttccagctaa atctagccga aggagtaaga
    36961 ggtcattttt ctgaccagga aatccaatat tgagaacata agggagatga tgttttcctc
    37021 tattcaagta atactgaatg ccctccagct ctgccagaaa ggcagtttct agattttgta
    37081 catgttgaaa atgttcttct tgtttttcta ggtcttcttt tagggctgca accatgccta
    37141 cgatagcagg cagattttca gttcctgcac gttttttctg ttcctggtct ccgccatgta
    37201 gataggaatc aaagtccatg ctagatgcgt agagaaaacc gattccctta ggaccatgga
    37261 atttgtgggc agaagcagtg agaaaatcaa tgcccaattc ttctgaatga attgggattt
    37321 taccaatagc ctgaactgca tcaacatgat aggcagcagg gtgttgcttg agtatttggc
    37381 caatttcagc gatgggcagt aggtttcctg tctcattatt ggcaaacatg gtagaaacca
    37441 aaatcgtatc gtcacgtaaa gccttttgaa tttgctgggc tgtgatttct tgattttctg
    37501 gctggataat ggttgcttca aacccaaagt gttgaaccaa gtaatcaatt gtttcaagga
    37561 cagcatggtg ctcgatggca gttgtgatga tatgttttcc ttgttcttgg tgacgaagac
    37621 agtagccaat gatggtagta ttattgcctt cagtcccacc agaagtgaaa aagatatgtt
    37681 gaggttttgt ccttagtaac tgggctagtt cctgacgggc ttctcgcaag agtttgccag
    37741 cttgacgacc atgaccatga atactagaag gatttccgtg ggtttcttgc ataaccttgg
    37801 tcatagctga aatagcaact gctgacatag gagtcgttgc agcattgtcc aaataaatca
    37861 aagaatcacc ttatttcttt ttattgtagg caaagagtgg gctgactggt tttctttcgt
    37921 gaatacggac gatagcatca ccaattaact cactagcagt gatgtagcat acatttttag
    37981 gagttttttc ttttgttgct actgaatcag tcacaagaat ttctttaata ttagtattgt
    38041 caagaagctc agcagctccc tcgacgaaga gaccgtggct agaaacagca taaatttctg
    38101 tagctccttc acgttcaacg attttagaag cttcagagaa ggtacgtcct gtatttaaaa
    38161 tatcatcaat caagatagct ttcttacctt caacatcacc aataatataa ccttcgttac
    38221 gagttgcatc gtcttgaggg tagtcgataa tggcgatagg agcatcaaga tattcagcca
    38281 ggctacgcgc acgtttgaca cctgaatttt tagggctaac gacaacaaca tctgaaccaa
    38341 gcaatccttt atcgcagtaa tgttttgcga ataggggaac agtgaaaaga ttatccactg
    38401 gaatatcaaa gaaaccttga acctgaacgg catgcaaatc aagagtcagg atacgatcaa
    38461 ctccagcctt aaccagcata ttggcaacta gttttgctgt aagtggctca cgaggacaag
    38521 caatgcggtc ttgacgtgca tagccaaaat atggaaggac aacgttgata ctgtgggcac
    38581 ttgcacgcac acaagcatcg accatgatta acaattccat taggtggttg ttgacaggga
    38641 aacttgttga ttggatgatg taaacatcat aaccacggac actttcttcg atatttactt
    38701 ggatttctcc gtctgaaaat tgacgtgatg atagttttcc aagtggggca ccaacagctt
    38761 gggcaatttt ttgtgcaatc tcttggttag agttgagtgc gaaaagtttc atgttttttc
    38821 tatctgacat tatagaccgt cctctgtaaa ctttataaat cctagttata tttaccttac
    38881 atatatgaac tgggatttgt gtatttttat cttttctatt ttaccaaaaa atggagatta
    38941 tttcagctat ttttcatact tttgacaaat cgaaccaatt ttgaaggagc tttttggtag
    39001 gaaatctgat ttttctctaa aaattgtcgg aaatcctgtt tgccttgctc atgattttcc
    39061 acttcaagct ccaattcgta atctgttata tcaaagtatc ggctctgatc cagtgccatg
    39121 agaccaatag ctgttttcat ttcatagcga agcgttgtta gacaaccaag aacctgccag
    39181 ttcttacttt ggataccatg tttcgccaat tcatccagta ctagcccttg aggaagttct
    39241 tccttactca gatagttctc agcatctttt agttgcaatt tttggttgta ttccatgttt
    39301 ccaacactct gcgggacttt gagtgtcaac tcagcccagt cttcaaaggt tcgaatgcgc
    39361 atagcgactt tcttttctcg cagttcaaaa tcaggcgtgt cgatgtagta atttgtttga
    39421 agaacaggag tgacacctgt gaactggtct tttagacgat tgtattcatc ttttttcaat
    39481 agtgttttca attcaatttc taaatgtttc atttttctta ccttttttta tcgttgaaag
    39541 cggatttatg gtataataag cattgtattt attgtatatg aatctggaga aaaaatcaaa
    39601 gatatttttg acggataata tgagaacaag ggagaatata tgaccttaga atgggaagaa
    39661 tttctagatc cttacattca agctgttggt gagttaaaga ttaaacttcg tggtattcgt
    39721 aagcaatatc gtaagcaaaa taagcattct ccaattgagt ttgtgaccgg tcgagtcaag
    39781 ccaattgaga gcatcaaaga aaaaatggct cgtcgtggca ttacttatgc gaccttggaa
    39841 cacgatttgc aggatattgc tggcttacgt gtgatggttc agtttgtaga tgacgtcaag
    39901 gaagtagtgg atattttgca caagcgtcag gatatgcgaa tcatacagga gcgagattac
    39961 attactcata gaaaagcatc aggctatcgt tcctatcatg tggtagtaga atatacggtt
    40021 gataccatca atggagctaa gactattttg gcagaaattc aaattcgtac tttggccatg
    40081 aatttctggg caacgataga acattctctc aactacaagt accaagggga tttcccagat
    40141 gagattaaga agcgactgga aattacagct agaatcgccc atcagttgga tgaagaaatg
    40201 ggtgaaattc gtgatgatat ccaagaagcc caggcacttt ttgatccttt gagtagaaaa
    40261 ttaaatgacg gtgtaggaaa cagtgacgat acagatgaag aatacaggta aacgaattga
    40321 tctgatagcc aatagaaaac cgcagagtca aagggttttg tatgaattgc gagatcgttt
    40381 gaagagaaat cagtttatac tcaatgatac caatccggat attgtcattt ccattggcgg
    40441 ggatggtatg ctcttgtcgg cctttcataa gtacgaaaat cagcttgaca aggtccgctt
    40501 tatcggtctt catactggac atttgggctt ctatacagat tatcgtgatt ttgagttgga
    40561 caagctagtg actaatttgc agctagatac tggggcaagg gtttcttacc ctgttctgaa
    40621 tgtgaaggtc tttctcgaaa atggtgaagt taagattttc agagcactca acgaagccag
    40681 catccgcagg tctgatcgaa ccatggtggc agatattgta ataaatggtg ttccctttga
    40741 acgttttcgt ggagacgggc taacagtttc gacaccgact ggtagtactg cctataacaa
    40801 gtctcttggc ggtgctgttt tacaccctac cattgaagct ttgcaattaa cggagattgc
    40861 cagccttaat aatcgtgtct atcgaacact gggctcttcc attattgtgc ctaagaagga
    40921 taagattgaa cttattccaa caagaaacga ttatcatact atttcggttg acaatagcgt
    40981 ttattctttc cgtaatattg agcgtattga gtatcaaatc gaccatcata agattcactt
    41041 tgtcgcgact cctagccata ccagtttttg gaaccgtgtt aaggatgcct ttatcggtga
    41101 ggtggatgaa tgaggtttga atttatcgca gatgaacatg tcaaggttaa gaccttttta
    41161 aaaaagcacg aggtttctaa gggattgctg gccaagatta agtttcgagg tggagctatt
    41221 ctggtcaata atcaaccgca aaatgcaacg tatctattgg acgttggaga ctacgttacc
    41281 attgacattc ccgctgagga aggctttgaa accttggagg ctattgagca tctattagat
    41341 attctctatg aggatgatca ctttctagtc ttgaataaac cctatggagt ggcttctatt
    41401 cctagtgtca atcactctaa taccattgcc aattttatca agggttacta tgtcaagcaa
    41461 aattatgaaa atcagcaggt tcacattgtt accagactag atagggacac ttctggcttg
    41521 atgctctttg ccaagcacgg ttatgcccat gcacgattag acaagcagtt gcagaagaaa
    41581 tctatcgaga aacgctactt tgctttggtt aagggagatg gacatttgga gccagaaggg
    41641 gaaattattg ctccgattgc gcgtgatgaa gattccatta ttaccagacg agtggctaaa
    41701 ggcggaaagt atgcccatac ttcatacaag attgtagctt cttatggaaa tattcacttg
    41761 gtctatattc acctgcacac tggtcgaacc catcaaatcc gagtccattt ttctcatatc
    41821 ggttttcctt tgctgggaga tgatttgtat ggtggtagtc tggaagatgg tattcaacgt
    41881 caggctctgc attgccatta cctatccttt tatcatccat ttttagagca agacttgcag
    41941 ttagaaagtc ccttgccgga tgatttcagt aaccttatta cccagttatc aactaatact
    42001 ctataaaaac tgtctcagag tataattatt atcttaaagg agaaaactca tggaagtttt
    42061 tgaaagtctc aaagccaacc ttgttggtaa aaatgctcgt atcgttctcc ctgaagggga
    42121 agagcctcgt attcttcaag caacaaaacg cttagtaaaa gaaacagaag tgattcctgt
    42181 tttgcttgga aatcctgaaa aaattaaaat ttatcttgaa attgaaggaa tcatggatgg
    42241 ttatgaggtc atcgaccctc aacattatcc tcaatttgaa gaaatggttt ctgccttggt
    42301 ggagcgtcgc aagggcaaaa tgactgaaga agatgtacgc aaggttttgg ttgaagatgt
    42361 caactacttt ggtgtgatgt tggtttactt gggcttggtt gatggaatgg tgtcaggagc
    42421 gattcactca acagcttcaa cagttcgtcc agctctacaa atcatcaaaa ctcgtccaaa
    42481 tgtaactcgt acttcaggag ccttcctcat ggttcgtggt acggaacgtt acctatttgg
    42541 agactgtgcc attaacatca atccagatgc agaagccttg gctgaaattg ccatcaactc
    42601 agcaatcaca gctaagatgt ttggcatcga acctaaaatt gccatgttga gctattctac
    42661 taaaggttca gggtttggtg aaagcgttga taaggtcgtt gaagcaacta aaattgctca
    42721 cgacttgcgt cctgaccttg aaatcgatgg tgagttgcaa tttgatgcag cctttgttcc
    42781 tgaaactgca gctctgaaag ctcctggaag tacggtagct ggtcaagcaa atgtcttcat
    42841 cttcccaggt atcgaggcag gaaatatcgg ttacaagatg gctgaacgcc taggtggctt
    42901 tgcggctgta ggacctgttt tgcaaggttt aaacaagcca gttaatgatc tttctcgtgg
    42961 atgtaatgca gatgatgttt acaagttgac cctcatcaca gcagctcaag cagttcatca
    43021 atagtgaaaa ctataaagcg atatactatg ctatactgta gttatgaaac tatgtacgaa
    43081 aagcactgcc attaattcct gagaactaaa ttactgattg gtgtcaaaaa ggaaaacttc
    43141 caagcgataa tatcctgtct atacacgacc tatagaaatc tgtaatatac atgtccgtaa
    43201 aacgataaat tccctttttg attttaaatg agtatgaaaa gaga
//
LOCUS       DAVLHM010000016        43185 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLHM010000016 DAVLHM010000000
VERSION     DAVLHM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.016"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VXE45_000877"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VXE45_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0788939.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VXE45_000878"
     CDS             complement(881..1867)
                     /locus_tag="VXE45_000878"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0788940.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VXE45_000879"
     CDS             complement(1830..2630)
                     /locus_tag="VXE45_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0788941.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VXE45_000880"
     CDS             complement(2880..3260)
                     /locus_tag="VXE45_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0788942.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VXE45_000881"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VXE45_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0788943.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VXE45_000882"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VXE45_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0788944.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VXE45_000883"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VXE45_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0788945.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4813..5988)
                     /locus_tag="VXE45_000884"
     CDS             complement(4813..5988)
                     /locus_tag="VXE45_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788946.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     gene            complement(5992..6579)
                     /locus_tag="VXE45_000885"
     CDS             complement(5992..6579)
                     /locus_tag="VXE45_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0788947.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMTDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6611..6799)
                     /locus_tag="VXE45_000886"
     CDS             complement(6611..6799)
                     /locus_tag="VXE45_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788948.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGSY"
     gene            complement(6979..9219)
                     /locus_tag="VXE45_000887"
     CDS             complement(6979..9219)
                     /locus_tag="VXE45_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0788949.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9203..9853)
                     /locus_tag="VXE45_000888"
     CDS             complement(9203..9853)
                     /locus_tag="VXE45_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV0788950.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9921..10490)
                     /locus_tag="VXE45_000889"
     CDS             complement(9921..10490)
                     /locus_tag="VXE45_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788951.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            complement(10712..11665)
                     /locus_tag="VXE45_000890"
     CDS             complement(10712..11665)
                     /locus_tag="VXE45_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0788952.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEEGPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            11913..12338
                     /locus_tag="VXE45_000891"
     CDS             11913..12338
                     /locus_tag="VXE45_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0788953.1"
                     /translation="MELSIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDVLLLFTYLHMAAAPEL
                     ADAMLAAKITGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            12339..12752
                     /locus_tag="VXE45_000892"
     CDS             12339..12752
                     /locus_tag="VXE45_000892"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0788954.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            12698..13024
                     /locus_tag="VXE45_000893"
     CDS             12698..13024
                     /locus_tag="VXE45_000893"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788955.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(13391..13651)
                     /locus_tag="VXE45_000894"
                     /pseudo
     CDS             complement(13391..13651)
                     /locus_tag="VXE45_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(13654..14154)
                     /locus_tag="VXE45_000895"
     CDS             complement(13654..14154)
                     /locus_tag="VXE45_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0788956.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            14190..14369
                     /locus_tag="VXE45_000896"
     CDS             14190..14369
                     /locus_tag="VXE45_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0788957.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(14347..15315)
                     /locus_tag="VXE45_000897"
     CDS             complement(14347..15315)
                     /locus_tag="VXE45_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0788958.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(15401..15616)
                     /locus_tag="VXE45_000898"
     CDS             complement(15401..15616)
                     /locus_tag="VXE45_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0788959.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(15625..16479)
                     /gene="cvfB"
                     /locus_tag="VXE45_000899"
     CDS             complement(15625..16479)
                     /gene="cvfB"
                     /locus_tag="VXE45_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0788960.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(16539..17096)
                     /gene="frr"
                     /locus_tag="VXE45_000900"
     CDS             complement(16539..17096)
                     /gene="frr"
                     /locus_tag="VXE45_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0788961.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(17105..17842)
                     /locus_tag="VXE45_000901"
     CDS             complement(17105..17842)
                     /locus_tag="VXE45_000901"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0788962.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(17926..19260)
                     /gene="trmFO"
                     /locus_tag="VXE45_000902"
     CDS             complement(17926..19260)
                     /gene="trmFO"
                     /locus_tag="VXE45_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0788963.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(19555..19809)
                     /locus_tag="VXE45_000903"
     CDS             complement(19555..19809)
                     /locus_tag="VXE45_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0788964.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            19804..20608
                     /locus_tag="VXE45_000904"
     CDS             join(19804..20172,20174..20608)
                     /locus_tag="VXE45_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0788965.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(20597..21243)
                     /locus_tag="VXE45_000905"
                     /pseudo
     CDS             complement(20597..21243)
                     /locus_tag="VXE45_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(21352..21870)
                     /locus_tag="VXE45_000906"
     CDS             complement(21352..21870)
                     /locus_tag="VXE45_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0788966.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(22097..22966)
                     /gene="rsmI"
                     /locus_tag="VXE45_000907"
     CDS             complement(22097..22966)
                     /gene="rsmI"
                     /locus_tag="VXE45_000907"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0788967.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(22969..23286)
                     /gene="yabA"
                     /locus_tag="VXE45_000908"
     CDS             complement(22969..23286)
                     /gene="yabA"
                     /locus_tag="VXE45_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0788968.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(23326..24216)
                     /locus_tag="VXE45_000909"
     CDS             complement(23326..24216)
                     /locus_tag="VXE45_000909"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0788969.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(24213..24851)
                     /locus_tag="VXE45_000910"
     CDS             complement(24213..24851)
                     /locus_tag="VXE45_000910"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0788970.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(25071..25868)
                     /gene="proC"
                     /locus_tag="VXE45_000911"
     CDS             complement(25071..25868)
                     /gene="proC"
                     /locus_tag="VXE45_000911"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0788971.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(25872..27134)
                     /locus_tag="VXE45_000912"
     CDS             complement(25872..27134)
                     /locus_tag="VXE45_000912"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0788972.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(27144..28274)
                     /locus_tag="VXE45_000913"
     CDS             complement(27144..28274)
                     /locus_tag="VXE45_000913"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0788973.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(28354..30237)
                     /gene="cbpE"
                     /locus_tag="VXE45_000914"
                     /gene_synonym="pce"
     CDS             complement(28354..30237)
                     /gene="cbpE"
                     /locus_tag="VXE45_000914"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0788974.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(30240..31127)
                     /locus_tag="VXE45_000915"
     CDS             complement(30240..31127)
                     /locus_tag="VXE45_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0788975.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(31117..31578)
                     /locus_tag="VXE45_000916"
     CDS             complement(31117..31578)
                     /locus_tag="VXE45_000916"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0788976.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(31575..32483)
                     /locus_tag="VXE45_000917"
     CDS             complement(31575..32483)
                     /locus_tag="VXE45_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0788977.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            32476..32673
                     /locus_tag="VXE45_000918"
                     /pseudo
     CDS             32476..32673
                     /locus_tag="VXE45_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(32725..33396)
                     /locus_tag="VXE45_000919"
     CDS             complement(32725..33396)
                     /locus_tag="VXE45_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0788978.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(33450..33671)
                     /locus_tag="VXE45_000920"
     CDS             complement(33450..33671)
                     /locus_tag="VXE45_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0788979.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            33943..34752
                     /locus_tag="VXE45_000921"
     CDS             33943..34752
                     /locus_tag="VXE45_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0788980.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(34933..35808)
                     /gene="aguB"
                     /locus_tag="VXE45_000922"
     CDS             complement(34933..35808)
                     /gene="aguB"
                     /locus_tag="VXE45_000922"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0788981.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(35818..36903)
                     /gene="aguA"
                     /locus_tag="VXE45_000923"
     CDS             complement(35818..36903)
                     /gene="aguA"
                     /locus_tag="VXE45_000923"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0788982.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(36900..38027)
                     /gene="nspC"
                     /locus_tag="VXE45_000924"
     CDS             complement(36900..38027)
                     /gene="nspC"
                     /locus_tag="VXE45_000924"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0788983.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(38027..39286)
                     /locus_tag="VXE45_000925"
     CDS             complement(38027..39286)
                     /locus_tag="VXE45_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0788984.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(39283..40143)
                     /gene="speE"
                     /locus_tag="VXE45_000926"
     CDS             complement(39283..40143)
                     /gene="speE"
                     /locus_tag="VXE45_000926"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0788985.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            40398..41113
                     /locus_tag="VXE45_000927"
                     /pseudo
     CDS             40398..41113
                     /locus_tag="VXE45_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(41079..42554)
                     /locus_tag="VXE45_000928"
     CDS             complement(41079..42554)
                     /locus_tag="VXE45_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0788986.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT        12486 a         9807 c         7843 g        13049 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agcatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggttgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaaaaga
     2461 tgggcatcgt ctggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtaaaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcata attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattac gaagttttgt atcaaagtca cccttgtcaa
     4201 tagttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttttatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tattttggtt tggttttcga atcaaaaaga
     4741 gagaatcaag ttgattccct ctctatgtta gtttttactt attttcccta cctataggaa
     4801 agctagaatc tattaaaaaa ttcttttttt ctgtgaactt ccccatcttt caataaatag
     4861 aattcccaat agcaaaaaga taatcaggca aggaagtaag accattccca tgctccaatt
     4921 tagatcgaca ttatcaatct gcttaggtaa tcttccagat aaaatctcca ctgaacgcaa
     4981 gtaagtaaag ggaatcagat gtgcaatcct ttgaagaggc tgaattgttt ggatgccaaa
     5041 caataagcca acaatcccaa tgagtgaaag aaagaggaca ggcatttttt gcttgaaaaa
     5101 gtaagcaatc aagtacacaa cttccacaat gacgataaag gctaagaaag ctaagagcaa
     5161 gccaggaaat aatacatctt gtattttccc aatagttact tcttgattca ctaagctata
     5221 aattgggtag ggataatcta actgtccaaa accacttatc agacttccca ctagaaaaga
     5281 aaagccacag attccgataa acagcacagt tacatatccc actccaactc caagagagga
     5341 tattgcaaat gtcacttttg aaacaggata taagtgagct gtgtccagat gattttgata
     5401 tctttctgca aatagttgtg ttagcataaa aataatcgca accacaaaca agcttgggat
     5461 gataacctct aaaatccaga caatctgatc aatcccgtgg gtcggaaact ccaaagtatg
     5521 tgcttttatg ttcaagggat acagggcttg gtaaatcttc cgttcgcggt caacccccat
     5581 ttttaagcca gagctagcag tcgggtcatt tgatacaaat tcataattct tctcttcatc
     5641 tttccactgc agatagtagg cttctttcca gcgcccttct tttagtaaag ttagaatttc
     5701 tgtctttcgc gtcaaaagat ttttttgcac gtctaaatta tttttagcaa actggtattc
     5761 ctccgagctg gtatcagaca tttgggagag tttctcttca ttttcattga tagccctctc
     5821 gttggctgca atgcgacttt ccaacctgct ctccaagctg tgtgagtttg cagtctgact
     5881 atttaaataa aaggtaacac cgagtacaga tacaaataaa gctaagataa tccagtttaa
     5941 acgacttttg aaaacttttt tcaataaaaa tagactaaca tctttcataa actaaacctc
     6001 ttctatctgc ccctgatgaa tggttactac tctatcgcag atatcaacca actcttcctt
     6061 atagtgggaa cttaaaagaa ccagctgttc ttgtctatcg atttgtgcta gcctatcaaa
     6121 aaacttctgt cgataatact cgtctaagcc atttgtaatc tcatccatga gccagcattt
     6181 ggcctgactg agaaaataca tagcaatcac caagcgttgc ttcatcccta aggaatactt
     6241 gcggatggga agactgatat agtcagtcat ttcccagtag gcgatttcat ctctcaagtt
     6301 taggtctgac ttccagatgt tttttatgag acgaaggtag tccatcccac ttaagtttcc
     6361 atccagccat tcaacgctct cataataaaa caaagaagga ggaactgcga tgtgtccact
     6421 actaagggga agcaacttgc tcatagctcg gaatagtgtc gtctttcccg agccattgat
     6481 agcaagaagg ccataaatcc tacccttttt aaaggtaaaa tccgcatctt gcaagatgac
     6541 ttgtcgcgtt tttaaggtaa catgagtaag atttaacata tccagccctc cttttctcac
     6601 tctttaagga ttaataactt ccagtatagt agtttatgac ctcataacga gcgtagttcc
     6661 agcctccgcc aactttatac tcagaatagc tgtaataacg agaccattcc ggaatccaag
     6721 catactgatg gtcgtgatag ttggtactat attccaaaac cgtattccaa tcatacttgt
     6781 aacttttagt gactgtcaca gcagatacac tggactgaag aagaccaata gattataaac
     6841 taactaacta aaacaacttt tgctgatttt taatgatttt atatcctcaa tattgaatac
     6901 gttttcatta tgccgttttt atcattatta tgcaacaaat ttttagttta tttcactaat
     6961 ctacaacatt tatccttcct atcgaacact ttcgattttc caactatcca accccttaaa
     7021 acgtatagct ccttgctggt cagttcgata aactttgcta ttgatacctt ccagtcgtgt
     7081 caatgtttcc tgatggggga gtttcattcg attgctcttt ccaactgaga taagagtaag
     7141 ctctggtttg agtttttcta gaaaggctgg acttgatgat tttttattgc catgttggct
     7201 agctttcaaa acatttactt tcaagtctgg atagtgcttc agcaagtcct tctctccttt
     7261 ctcctccaaa tttcccgtga agagaaattg cttatccaag aatttcccat acagaactag
     7321 ggtatcatcg tgtcctccat ctcccatttt ccttggagat agaacttcta actgacttcc
     7381 aaaaatgggc aagttctccc ctactatcat actacgcacc tttgtttgag tcgcctgtag
     7441 ttctgccaca aattccttct gtttcagact gtcttttgat actagaatct cccctacatg
     7501 gaaagccttg gtcatctctg acaaatctcc aacatgctcc ttgtccgtgt tagtcaaaat
     7561 tagctggtca atcttagcta ctcctcgact tttgagatag ggtatcaagc ttcgctgggc
     7621 attgctggtc gtcatctttt cttgccattt tttgattttc ttataagatt ctgccttacc
     7681 acctacatct atgagaatgg ttttcccagt tacatcccgt aggaaaatac tttctccttg
     7741 ccccacatcc agcatggtga tttcattttc cagtggatgc ttggtcagga gaaagagccc
     7801 tgtaatcaat aagcacaata ccgttagctt tttaatgttt ttcctcaaat catagaccaa
     7861 agccaaagaa attaacaata ggattaaaag ccattcattg ggttgtccaa agacaagcgg
     7921 tctacttgcc acctgcgaga ccaagcgaat aatgccctct aaccattcaa agataaagtt
     7981 cagctgaatg actggataga gaaaggaaag gacaaataag atagacaaga gcggtaagaa
     8041 gaccaagtca aaaagaaagg aaaagacaaa ggtcaaaagg atagaccaag gttgaaattc
     8101 cgcaaaatag aaggatagaa tgggcaatat gcccaaggag atgactagac tttcactagt
     8161 aacagccttg agcccctccc cttctttgct ggtcatggtc aggataaaag cataagcaca
     8221 ggacaagact cctcctgctg tcaagaaaaa gtttggcatg acaataaaga ggacaagcac
     8281 cgtcaaggca aaattatcca agcccttaac cccatgttga gccagtagct tttgcaagag
     8341 actgcgaata accgatgctg aaaatccagt tagtcccgca tagataaggg aaaagggata
     8401 agtcagccac ttcaactttt cttgtgtcaa gcccaatcgt aaaagtagtt tcttaaatcc
     8461 gtccatgaaa aaccctacct gcatacctga caaggcaaaa aggtgaataa ttcctaaact
     8521 ggaataaagc tcattcatct cctcaaaatc ggtgtccaga tgtcctagca agagtcctgt
     8581 catgtaattg cgcatagggt ctgggaagtg catcttaatc caaaccacag cctttcgacg
     8641 taaactggac aggttttcac ctatatccca actgccaacc ttttggagtg actggattct
     8701 tttaatattg agtgtctggt aaattccctg agtcttcaga tagccttggt agtcaaagcc
     8761 accaaaattt ctctgccctt ctggctccga aagcttccct tctagtccta tctcatgaag
     8821 gtcagttaaa gcttgaaagg cttctttctc ctcctcggac tggagtttat aatagacttg
     8881 gaaagcacga ccatcagact taccacgaaa ggacagactg tcaccgttaa ccttaatagt
     8941 gtctggtaaa atccgtaccc tttcaacaga atccaccaaa ttttgactca cttgactctg
     9001 ttgccaagtt tgaaacagaa accagaagcc aaagactcca caaatcacta gaactttacc
     9061 tgctgatttc caaggaaatt ggataaagag gcagactagc agaaaaacaa aacccaacaa
     9121 agcaaaatag gatactgaga aaatggcgta gtaaagccat agtaacagaa aactcaggta
     9181 aattagggga atagagaaat tcttaatcca ctgtaacata gtctttaagt ttttctatgg
     9241 tcttggcacc aatgccagag accttcttga gctcgtctac tgacttgaac ttgccatttg
     9301 cctcacgatg gtcaataatg tcctgagctc gttttcctcc cagtcccttg acctgcttga
     9361 gttcttccag actggccttg ttgagattga ccttcttttc cttgcttgtt gaagaagctg
     9421 tccccgaacc agtctgttga ctaactgctt cttctccctt agtaggaacg taaaccagag
     9481 cctcatcact aactttctga gctagattga gcgacttgct gtctgcttgc tctgtcaagc
     9541 caccagcctt ctgaacagca tcattgactc gactacctac aggcaagtca taaatccctg
     9601 gcgatttgac agcacctttg acatctactg tgattagatc ttgttcaact ggttcttcct
     9661 tctcttcctt gttcacttcc tttccggtcg atgagtcctt ggaaacagct gcaacttcag
     9721 cctgcaaatt cgtctctttg acagatgttt gtggagctgg ctttagcagg aaaaatcctc
     9781 ctacaagcaa gcccagacca gtacagatga cgatgatttt atactctttg attttctcga
     9841 taattgcttc catattttct cctctcttag attattcgta agaggaagaa aaaacagtcg
     9901 aaaaatttct tttcaactgc ttatttattt gcaaaatagt cttccttggt caagacataa
     9961 tgaactcttg tcacgattcg gcctttttca tgctggtcca tacaagcata tggttctgca
    10021 tgggaaaaac gcatgcctga tttctccatg acctttcctg acgcgggatt agccttatcg
    10081 tgaagggcag tcaacttatt catccctatc ttctcaaaag ctagctcaat cacagcacga
    10141 ttggcttctg tcgttaatcc ttgattccaa tactttttat tgataatgta gccaatagct
    10201 gccttcttaa gaacaggatc aatcttgtgt aagtcaatag ttccgataaa cttgccgtta
    10261 tcttttaatt caatccccca acgtcccaag ggattagcca agtagaactg agcaatgtta
    10321 ttcttggttt cttccaagct ttgattggtt ggaaaagtgt aacgtgtatt acccttgtcc
    10381 gaggcatagt caaacattgc ttccgcatca tccaaagtta caggtctaag caataaacgc
    10441 tccgtttcta tagacggata ctgggcaaat ttcacaaata ttgattccat acttttccct
    10501 ccattagagc ttgattttca ctagtctagc ataaaaaaat ttggatgaca agtttttctt
    10561 gatttttgaa gcggtttcat atacaatgaa accgtcacat ttttgattta tgaactggaa
    10621 tgtgacaacc aaaacaagac cgtcaattga aaggtaggtt atctcaatgt taatcggaat
    10681 cccaaaagaa atcccaaatt tcaagttgaa gttagccacc caaaagaaat tcacttggcg
    10741 acttgtagtc caagcatttt ttagggtagt tgttaatcca attttcgata aaagctactt
    10801 ctttcggagt cgttttcttg gttcctttag gtaaccatct ccgaattaat cgattatgat
    10861 tttcatttga acctctctcc catgaagagt aagcatgtgc gtagtagata tgttcctcag
    10921 gaaatacctc agacaatcgt ttgaactccg aaccattatc tgcagtaatg gacagaatac
    10981 gatgctcccc taatagtaac gtaagcgcct gattgacaga ttcagcagtt ttatttggaa
    11041 ttaaccttat aatttggtgt ctgctccgcc ggtcggttaa gactaacagg caataatttt
    11101 ttatcttagt cagtaggacg gtatcaattt cataatgacc attttccaag cgaagattaa
    11161 taacgtcagg accttcttcg atagatttac ctgccggctt aaagttcgga ctagcttgct
    11221 tcttgacacc tttccttttt ctgggataaa gcatgtcggc cttcgtcaat cctaaatgac
    11281 cattatgaaa ccagtagtag atggttgaaa taccaacttt cacttgcttc ttgttaacca
    11341 tcatttcagg cgaaaatttt tgcttatgat agtgtaagat cttctctctg atttcctttg
    11401 ttaaaattaa ctttttcacc gaccgttttc gattgaattg gtaaacagtt tgtgcgtaat
    11461 cggcagaata gacctttttg tatagccctt ttctcacttg ttgtaaagtt gtacctcttt
    11521 tgacttcatt atgaatcgtt tgaggcgcct ttcctaacaa gcctgcaatt tcacgattgg
    11581 acttattttc attcttccac cgctcaatca agcgacggtt atctattgtc aaatgtttcc
    11641 cttttggggt ataatgttct tgcatctctg tgcctttcct tgtgtttgtg gtgaacaaca
    11701 agtatagcac agaggtgttt tcttatacct taaatcacat ttcatttgac aacaggaacc
    11761 cttgaacctg ttttttcagc taaaccaagg ctatgattag ccttggccac ctagcctaac
    11821 agtttcaaac ctgttatcaa atgaaatcat caacttactc aaacatagtg aaacatctaa
    11881 ttcttgacta aggtaaggtg gctaacttca ttatagaact ttcaatccca aaagaaatta
    11941 aaaataacga aaaccgtgtc gccctcacac ctgcaggtgt tcatagctta gttagtcgtg
    12001 gtcatcgtgt ccttatcgaa acaaatgctg gtctcggttc tggctttact gatgctgact
    12061 atcaaaagca aggagctgag attgtcgcta ctgctggtga agcttgggca gcagagttgg
    12121 ttgtgaaagt aaaagaacct ttaagttctg aatacggtta cttgcgcgac gttcttcttc
    12181 tcttcaccta cttgcacatg gccgctgctc cagaattagc agatgctatg ttagcagcaa
    12241 aaataacagg aattgcctat gaaactgttc gtgacaatca aggacaacta ccgctcctcg
    12301 ttcctatgag tgaggttgca ggtcgtatgg ctgtttaaat cggagctcac ttccttacta
    12361 agcaagctgg tggctctggt gttctacctg gtggtgtacc aggtgttcca aaaggaaaag
    12421 taactatcat cggtggtggt gtcgtcggta cacatgctgc ccgcatcgcc cttggtcttg
    12481 gtgctcaagt gactatttta gatattagtg ccaagcgtct ctcagttcta gaagaagtct
    12541 ttggaagtca aattcaaact cttatatcta attcattcaa cattgaagca agtatgagag
    12601 atgctgatgt ggtgattgga gccattctca tccctggtgc aaaagcaccg gaattggtga
    12661 cagatgagat ggtcaaacaa atgcgtccag gctctgtatc gttgacgttg ctgttgacca
    12721 aggtggcgtt atcgaaacag ctgaccgtgt gacaacgcac gatgaacccg tctatgaaaa
    12781 acacggtgtt ctccactatg ccgttgccaa tatccctggt gcggttgctc gcacttcaac
    12841 catcgcccta accaatgtca ctcttcctta tatcgaagct ttggctggca aaggattcgc
    12901 acaagcaatc tctgaagatg aaggcttgcg tcaaggtgtg accacttatc aaggttactt
    12961 gactagccta ccagttgctc aaggacttaa tcgtgactac actgatatca atgatttagt
    13021 ataaattttg aaaagaaaag ggtgacttcg caagtcctac ccactgtgct ttgtgtcatc
    13081 agctattaca tcgttggttt attgtactgt atactttgca actggagact ttcgttccag
    13141 actcaattgt gcataagaaa ctctaaattg aataaagtca acagagtttc gcccaaccac
    13201 ttcgtcttgt aatgacaatt atataaacca aaggaagctg agctctttag tcccagcttc
    13261 tttttatata taaaatttta cccgtgcaaa gacagggcct tagcagactt cttttttact
    13321 tcgttcaccc ttgctttttc tttttaggtt tgggcgttgg cagttggtta tacatagcta
    13381 aaatcaggtc ttatagaaac atcttattat caagttcttc cactcaaatc atttctttgg
    13441 cacctttgta tggaaactca aaaaaagatt ggtcaatctt atctaagact gcttgcacgg
    13501 gtttaactaa aaagcgatca tcataaatgc cgccaataat cttgccgcgg aagtaaagaa
    13561 tatactcccc catcatggaa cggtaagtca catcatctaa tcctgataat tgttccaaaa
    13621 caaattccaa atagttctta cttgatgcca tttctaatct tctaggctct gttcagcgat
    13681 aacaaccgta tagagttctt gcttaacctc gcatccaatt gatttaaagc cctgcttttc
    13741 ccaaaaatgc tgagattgcg gatttccctt aacataagcc aaacgtgcct ttcgaaagtt
    13801 cttagcaaaa taagctagtg cttctgtcac aatatgacta ccaatccctt tcctctgata
    13861 ggcttgatca accataaaca aaccaataaa aacagtctcc tcatcaggat gtgcatagac
    13921 aaaatctata acagccacaa ggtcagatcc attccaaaat ccaacaaaaa acttatcagc
    13981 cttagcttta ccttcaggta gacaaagcat gtcctctttt acagttgcaa aatttggctc
    14041 tggtggacaa tgctgaaaat acagaggatt actttcatat aaagataaaa tacttggaat
    14101 atccttttca gttagtatcc tacaactgta atacttagat agttggtcaa tcatcttttc
    14161 aaattcctac tttcttgtgc cctgtgatta tgacacagga agatgcactg atcgtcatca
    14221 gccacataaa agttctttcc atcgtgccta atcgttgtct caaacctttg gataaaacct
    14281 ttagcctata caactggatt ttcctctctc aaaagtatat tcttttgcag gcaaacttcc
    14341 tcaaaatcag tcgtgtgcaa cttcagtaga atattcatag gctcggataa tctgagcgac
    14401 aactggatgg cgaaccacat ccttggctga aaaatgaaca aagtcaatct gatggatgtt
    14461 cttgagtttc tcttgagcat caatcaaacc ggacttgaca ttacgtggca ggtcaatctg
    14521 actaatatct ccattgacaa tcatcttaga atgaaaacct aaacgagtca agaacatctt
    14581 catctgcatg atggtcgtat tttgcgcctc atcgagaatg acaaaggcat catccaaggt
    14641 ccgtccacgc atataggcaa ggggcgcaat ctcgataatt tcacgctcca tgagtcgagt
    14701 tgtttggtct ttccccagaa tctgatacaa ggcatcgtaa acaggacgaa ggtaaggatc
    14761 caccttctcc ttaagatcac ccggaagaaa tccaagactc tctcccgctt ccaccgctgg
    14821 acgagttagg ataattcgct tgacttgccc acgtttaagg gcagtcactg ccaaggtcac
    14881 tgcaaggaag gtcttccctg tacctgctgg cccaattcca aaggtcacat catgctgttt
    14941 gacactgtcc acataaagct tttgccctag ggttttgaca cggataggtt tcccagtatt
    15001 atctttgata atttcttctt cgtaaagggc gacaaacttg tcaatttcat catttttgac
    15061 catgctaatc gcagtgacta catctggcgt accaacggtc atcccacgat ttaccaagac
    15121 catcaaagcc tgaataactt gacgggcttc ctcacaggca gactcttctc ccaaaacctg
    15181 gacaatctcc gtacgagcat gaatcacaac atcaagctct tcttccatca aacgaagatg
    15241 gcgttcattg gaaccaaaaa gatgaaacag gtcatctgga tgactcagtt gaatgtctat
    15301 tgaatgttcc ttcaaataaa gaacctctct aatcctttta tttcttttta ttatagcaga
    15361 gggatggaga aattactagc ccaaacccaa tgaataaatg ctagtgttct agatattcct
    15421 gccaaatgct gtcaaaatct cctaggttaa aagagaaact ggcatgctcc tccaaaaagc
    15481 gactgacctc atcaaaatca tctgtatgtt ttggaaaagc tgcctcttca aaagcgaggt
    15541 ctgccaaaat tgctttggga ctgttacttt taggattgcg ctcggtcatg agccaagtgt
    15601 aaaatgattt tctcataagc ctccctaaat caactctgtc ccaaactggt cctgcttgat
    15661 tttaccagcc ttcataagac cacctaaagc tttcttgaac tgacctttag aaatgccaaa
    15721 ggttgccttg atgtcgtctg gagatgactt atcatttaag gtcatgaaac cgccattact
    15781 ttccaaataa gtcaaaatca tctgagcatc gttttccaac atttcaaagg agcgtggttt
    15841 gagggagagg ttcagagtgc ggtccacttc acggaaacca ataacgcgcg catctaatac
    15901 ttgccccaaa cgtggctctg cgtaacgctc gctaggatga ataaaaccaa gcatattatt
    15961 ttctggtagg taaacaaaag ttcctgacag cttgagacgg taaacaatgg ctggccagtt
    16021 ttggttctgc atgttgttgt aggcaggacg agcaagacgt tggaagtctt cttgataagc
    16081 caagaggccc cagatacggt ctttcttatc cacttcaaga cggatgtaga gttggtcgcc
    16141 cttcttaggc cagagttcct tgagctcagg gagaatatcg agtgacacaa cgatttcctt
    16201 gtcaggaagg cctgtatcta caaagacacc caagtcctta cgaacctctg tgacacatcc
    16261 ccaaccaaat tggtcctgag tggcagtcac ttctaaggtt gtcaggcgga gtttttgctt
    16321 catatccgtg tatgcaaaac ctttgaccgt atcccctact gtatgttggc cctcttcctt
    16381 agcaagagca taggtttgac catccttttg cacaaagtaa aaacggtcat tttcatcgat
    16441 gatcagtcca acgataaaac ttgcaagatt tgtattcata tttccttctt tcgaataaaa
    16501 ctcagccagc aatgccaact gagtttttct gtttattttt agacttccaa aagttctttc
    16561 tctttgttag cagtcatgtc gtcgatgtgt ttaacagcat cgtctgttac tttttgaata
    16621 tctttttcaa gagtcttcaa ttcgtcttca gtgatttctt ttgctttttc ttgtttctta
    16681 gcttcgtcca tagcatcgcg acggatattg cggacagcca ctttagcatt ttcgccgacc
    16741 ttcttcactt ctttagcaag gtcacgacga gtttcttctg taagagctgg gataaccaag
    16801 cgaatcacag aaccgtcatt agccggtgtg ataccaagat cagaagcgtt caaggcacgt
    16861 tcgatgtctt tcaatgaaga cttgtcaaat ggtgttacca acaaaacacg cgcttctgga
    16921 atcgtaattg aagcgatttg gttaagagga gtttcgactc catagtattc tacatgtaca
    16981 cggtcaagca agcttgcatt ggcacgacca gcacggatac caccaaattc acgagcaagt
    17041 gattggtgag attgggtcat tctctcttta gctttttcaa taattacgtt agccatattc
    17101 tttcttattc cttttcttcg atattatttg aaactgttgt tccgatattt tcaccaaata
    17161 cgacacgttt gatgttgcct gattggttca tgttgaagac aaccaagtca atgtcgttgt
    17221 ccattgagag ggttgaggct gttgagtcca tgatacgaag acctttgttg ataacatcac
    17281 ggtgggtcaa ttcttcaaac ttaacggctg tcttgtcctt cttaggatcg gcattgtaca
    17341 caccatcgac gccattttta gccatgagga tggcatctgc ttcgatttca gctgcacgaa
    17401 gggccgctgt tgtatctgtc gagaagtatg gtgaaccaat tccagcacca aagataacga
    17461 tacggccttt ttcaaggtga cgaagggcac gtccacggac ataaggctct gccacttgtt
    17521 gcatagcaat agctgtttgt acacgcgtat caaccccaac ttgttgcaat gaatctgcca
    17581 tcacaagagc attcataaca gtcccaagca ttccagtgta atctgcctga acacggtcca
    17641 tacctgcttc tgctgcaggt tctccacgcc aaagatttcc tccaccaata acaagggcaa
    17701 tttcgatacc taagctatga acttcttgaa tctcttttgc gattgtttga actgtttgga
    17761 tatcaatccc tacgccacgt tcaccggcaa gggcttcacc tgataacttg attaaaatac
    17821 gtttatactt gggattcgcc attttcactc tccttctttc atcctaccta ttttatcaca
    17881 atttctaaga tttttatagt atcatgagca attctttcaa aaaaattaga cagtcaaaaa
    17941 ttcctctaag tcggcaaggg cacgctctgc aattttttca taacgagcct tcttatcacg
    18001 gatacgctcg ccttccaact ccttgatgat cccaaaattg acattcattg gttggaaatg
    18061 tttgctgtcg gcatgggtaa tgtaatgagc taagcttcca atcgctgtcg tctcggggaa
    18121 aataacctcg ctttcttcct tgaagagacg agctgcgtta attcccgcaa ctaagcccga
    18181 agccgccgac tcaacatagc cttccacccc cgtcatctga ccagcaaaga agagatttgg
    18241 ttgtttcttg gaacggtaag tctgctcaag aagatttggt gaatccatgt aagaattgcg
    18301 atgcatgaca ccataacgga caaactccgc attttcaaga cccggaatca tttggaagac
    18361 acgcttttgt tctccccatt tgaggtgggt ctggaaacca acaatattgt agaggctacc
    18421 agctgcatta tcctgacgaa gttgcacaac cgcataaggt gttttaaatt ctccatcacg
    18481 aggtcctgtg tagtcgtccg gatactcaag accgactggc ttcatagggc cataaagcat
    18541 agttttaatg ccacgtttgg ccataacttc gattggcata catccttcaa agtacttttc
    18601 tttttcaaaa gaattgagcg gtgcttcttc cgcattgacc aaggcttcat ggaaatccat
    18661 aaactcttgc ttggtcattg gagcattgag ataggctgct tctcccttat cataacgaga
    18721 tttgagatag accttactca tatcgatagt gttgacatcg ataataggcg ctgctgcatc
    18781 gtagaaatag aagccatcgc cattattaag ggcatgaatc ttttcagcca gggcatcgct
    18841 agtcaaggga ccagtcgcca caactgtaat aacatctgtt ggcaattctg taatttcatc
    18901 acgcaccact tcaatcaagg ggtggttgac cactttttcg gtcaccattt gagagaaacc
    18961 atcacgatcc accgcaaggg ctccaccggc aggaacacgt gtagcctcag cagattccaa
    19021 gataacagaa cccaagcgac gcatttcttc cttgagaaga ccaactgcat ttgtcaaagc
    19081 atccccacgc aaagaattgg aacaaaccaa ctcagcaaaa ttgtctgttt tgtgctgagg
    19141 agtcgacttg acaccacgca tttcataaag tttaactgga ataccacgct ctgcgatttg
    19201 gtaggctgct tcagaacctg ccaaaccagc accgataaca ttgatataag attgagacac
    19261 gacactaata cctctttggg agtgtgaagt taagattcac attgaaaaag ccaatcagac
    19321 ttacgagatt tcgagtttct tggctcaggc tgaaaaagtc ccccagactt tcctcgctct
    19381 cgaatttctt ggctcaagct gaaaaagtcc cccggacttt ttcactccca caaatctttc
    19441 tatttttttc ttctactagt ataacaaaaa aagggaagaa ggcaaacttc cctgtttagt
    19501 cattttcttg atgtaaagag atagagagta ttccagttaa gaatcaatta tatgctactc
    19561 tataaaatct tttccacata acggatcgat agggactgtt attctatctc ttgctataac
    19621 cgtattatct aaaacagcat aacattcaac atagtgatct cctttaaact gtgaatcttc
    19681 gtgatatttt attttacctg aaaaaatagc accacgctca caatttcttc taatagcctc
    19741 agcttcaata tttcttactt tccaatagac ttcctgcgaa acaaaatatg gtatagtagt
    19801 tctatgaatg atgaagcaag taaacaacta actgatgcac gatttaagcg tcttgttggt
    19861 gttcagcgca cgacttttga agagatatta gctgtattaa aaacagctta tcaacttaaa
    19921 cacgcaaaag gtggacgaaa acctaaatta agcctagaag accttcttat ggccactctt
    19981 caatatgtgc gagaatatcg aacttatgaa caaattgcgg ctgattttgg tattcacgaa
    20041 agcaacttaa tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag tggtgttacg
    20101 atttcaagaa ctcctctcag ttctgaggac acggtaatga ttgatgcgac ggaagtaaaa
    20161 atcaatcgcc ctaaaaaaac aattagcgaa tcattctggt aaaaagaaat ttcacgctat
    20221 gaaggctcaa gcgattgtca caagtcaagg gagaattgtt tctttggata tcgctgtgaa
    20281 ctattgtcgt gatatgaagt tgttcaaaat gagtcgcaga aatatcggac aagctggtaa
    20341 aatcttgtct gacagtggtt atcaagggct catgaagata tatcctcaag tacaaactcc
    20401 acgtaaatcc agcaaactca agccgctaac agctgaagat aaagcctgta accatgcgct
    20461 atccaaggag agaagcaaga ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt
    20521 ttcaacaatc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg
    20581 cattatcaat catgaactag gattctagtt ttgcaggaag tctaatgtaa ttctcaagct
    20641 gtgagttcat tatgatttgt aaatccgata tatcttcagc agctaaaaac acattttgaa
    20701 atgttccaag tccgttttca ccaaaactat attctctctt actatactta ctcttattat
    20761 tctctatata gttagagtca aggttcttaa cctcttgaag ttcattttct ttacttctga
    20821 ggttaaaatc ttttacttct gaagttaagt tttttgactt ctgtaagtca ttttctttta
    20881 cctgaaatat actcataaag tctttaacat aaatgatgtt cggcttacca agtccaagcc
    20941 ttactctttc gatcagtcct attccttttt tacatcaagc tcatctaatg tttttatggc
    21001 agttggcttt gagatatttc ttcttttcat aatttcttcg acagtaaaat agataaatac
    21061 tctgccttcc ttgtctatcc agttattctt aaatgacatt cctgtctgtt taagaagtat
    21121 ggaataaagg ataattgctt ctgctgataa gccccgaaat tcttctctat caactaatat
    21181 ctccggtact tttaagaagt taaatctttc cgcttctctg ttataaaaat attcaaagtc
    21241 catgcaagat cacctccctt cttaaaaatt tgcaaagaaa aagacgatag tttttcttct
    21301 atcgcctttg gtaaccattt ttatgaaatt ttttaaagtt aaaaatataa tttataatac
    21361 tatcttcttc cattttctga ttttagttct gaaagttcca aaaggtgcaa ccgtatttac
    21421 atgaataaac ttatacactt cccaagtcgc tgttttagtc gcttcatcag cccactttct
    21481 catatgcggt tcaaataatt cttcctcact caacgaatca atcattgcag agatagaatt
    21541 aatattttca tttaattttg ctttcaactc ttgcagagat aaatgagcgt aggtatctgt
    21601 gaaccactga tataattcac caagttgatt ccatttaaat ttatccgatg gtgtttttac
    21661 ttgaagcccc tttctttcat cttcttccca tttaagaacc aagttggtcc aaccaacctg
    21721 ataagcaagg ttttctgctg gagttctgtc aacttcatca gctctcttat cttttaaatt
    21781 ttctggaata ttatcaaatt ctaaaatata tttctcaaat gttttctcta tctcagcttt
    21841 tagttcttct ttattttcgt atgttcgcaa aaaatcacct tctttctgat ttatcaatcc
    21901 tttgatttaa aatgacctta tttttctatt tataccttct aagaacgcta taactgctgc
    21961 tccaaccatc ggtattccgt atgggcttaa taaaaaactt aataccaaag cttctatacc
    22021 aagtgataca tctttatatt atcatcacta attaagttaa acagaaacag acagaattat
    22081 tacatcctgt ctccctttat tgtttttctt cccagtcgtg gtaggcagcg tagagctgac
    22141 ttttattcca ctggtaaatc ttagcgactt ccttgatagc ttggtttttc ttcacacctt
    22201 gctggatgcg ggtttgaatt tctacgaaca agtcttcctc gtccttttcc tccacaccct
    22261 gactggcacc ctcaacaatg agaagacatt cgcccttgag tggcgtttca gcaatgcttt
    22321 ctaataactc agagatagta cctcgttggt attcttcata gattttggtc aattccctga
    22381 ccaagacaac ggagcggtca ccgtagactt ctaacatatt ttccaacgtg tctgctacac
    22441 gatgaggtga ttcataaaaa atctgtgttt caggataatc ttttttcaag ccaaaaaatt
    22501 gcttctgctg acctgatttt ctcggtaaaa aaccgtaaaa gatatgtggc tgtggcgcta
    22561 aaccactggc aatcaaggca gaaattcctg cagaggcacc tggaactgtc acaactgcaa
    22621 tttcttcctc aatagctgcc ttaactaaat catgaccagg gtctgaaatg ctaggcaaac
    22681 cggcatcaga gacctgagca atactttgcc ctgctttcaa gaaaccaatc aaatcaggaa
    22741 ttttttcctt ggcattgtgc tcatgaaaac tgatctgctt ggtggaaatg tcaaaatgct
    22801 tgagcaaaag ccctgtattg cgcgtatcct cagcagcaat ccagtccact tctttcaagg
    22861 tctggatagc acgaaaagtc atatcatcta gattgccaat cggcgttgcc actagataca
    22921 gcttgccata gggagactgc cccttaaaac ttttttgaat ttgcatgctt actccctgta
    22981 taacaactca tcacagaaca tacattcttc gtcctgctct cgacgttgtc cataaaaatc
    23041 attacatacg tgaaatccat cacggtaaat acgacggaca ctttcgcgaa catgcttggc
    23101 cttgacggga gcgtctgctt ccacctcacc caagcgttct cgcaacttac tattttccaa
    23161 gcgaagagct gtattttctt ctaccaagct cttgagattt ttcttgatgg cttccacatc
    23221 ggctaaggtt accaataatt gttgggaaaa atcatccagc gcgtcaaata attctttttt
    23281 gtccataaaa cagccctttc ctttctttat cattcatttt tgagtttata tttctttcaa
    23341 gaccagatat tccatggcat tttgaaagct gacattagct tgccacattt ttctagcttc
    23401 tagtaaatct tgtagaatca ctcttactct tacctgcaag aggtcctgcc cacagagaac
    23461 ttcaagaatc cgtaaaacct gatcctgttt ttccttatca tctgccaagt tggctaattt
    23521 ggcaacctgt agataacttt cttttttctt agctactaac caagtcagca ggcgttcact
    23581 ttcatcgacc aaggtccaaa aacttgcctg attagccaac ttttctgctt cagctcgcga
    23641 ttgactaaac ttagctaaaa gagtcgcttt tttcttaaca agtcccattt gttctaagag
    23701 taagataagt ttttcttctt gctttttaaa gtggaagatc tgagtccgac ttcggattgt
    23761 cggtaacatc ttttcctcat cgctagtcaa gaagaaaata taaacttcac tctggggttc
    23821 ttcgatgacc ttgagcagag aattggctgc gttgggatgc attttatccg cttgctcgat
    23881 aataaagacc tgttgctggc tttcaatccc tgcttgagaa aactgtccca ccaattcccg
    23941 aatgcgttct gtcttgatga cctgattgac tggcttaatc aaggtgacat ctggaaactc
    24001 ttcctgttca atcagcttgc aacttcggca tttctcacat ggtaagacgc caactttatc
    24061 cgtacaaaag aggctcttag ctaaaaattg cgccatttcc aagcttccaa agaaacctga
    24121 aaagagatag gcgtgattga gctggtcttg ttctaagata cggacaaaac ggtcaaactg
    24181 agctggttgc caagccttta gttgatcttg tttcatttgg ccaagtccat tccgtcaaac
    24241 aagacagcct tggtagtttc cacaacttgc tccaaaggga gactagcatc aatcttgaca
    24301 atgcgatttc cttctttttc caggagagaa aggtagcctt gacggacttt cttgtgcaat
    24361 tccaaacctt ccaagtccag acgattgacc tcgcggtcac tattcgcagc aatgcgagcc
    24421 agcccttctt ccacctcgat gtcaaaatag agtgtcaaat cgggtttgag gccatctgtc
    24481 gcaaactgat tgagccagtc aatggcttca atatctaagc cacgaccaaa tccctgatag
    24541 gcaacagaac tatcgataaa acgatccatg atgaccaact tgccagcttc aagggctgga
    24601 agaacttttt ccaccaaatg ctgtctgcga ctggcaatat agagaagtag ctctgtttta
    24661 gcatccatct gagtatgact tggatccaaa atcacttccc gaatcttctc cccaatcaag
    24721 actccgccag gttcacgggt cgtcagcacc tttactcctt tttcctctaa aattggtagc
    24781 agagcctcta aaacactggt cttgcctgct ccctctggtc cctcaagaga gactaaaaat
    24841 ccttttgaca tgtctaactc atttcttttt tactacttct attctatcaa aaaaataggg
    24901 gtttgtgaca atctttttgt cttctcattt catactcaat gaaaatcaaa gagcaaacta
    24961 ggaagctagc cgcaggctgt acttgagtac ggcaaggtga agctgacgca gtttgaattt
    25021 gattttcgaa gagtatcaac caccataaaa gaggcagata aaactacctc ttatttacct
    25081 agttcttgtg ttcgtttgta ggcttgatga actgcatcca tgactgttcc tcggaaagca
    25141 tgcgcttcta ggcttgctac accagcgata gtcgaaccgc ctgggctaca gacttggtct
    25201 ttcaatactc caggatgttg ctgactttca aggaccaatt gcccagctcc taccacagtt
    25261 tgtgctgcca ttttcaatgc tatttctcgt ggtaatcctg tctgaacacc tgcatctgcc
    25321 aaggcctcga taaaaagata gacaaaggct ggtccacaac ctgcaagacc tgtcgctgca
    25381 tcgattaaac tttctcctag ttcaaccaag agaccagcct tggctaaaag ctgataaaag
    25441 agctcactgt cctcagccct gcaattagga gacaaggcat aactaatcac tccttgcccg
    25501 atagaagcag gggtattagg catcatacga ataattcggt gttgacttgg gataagactt
    25561 gctagttttt ctaaggtcaa tccagctgcc atcgaaatca aaagaagact ttctcttttt
    25621 tcaaggatgg tctggtattg agaaagcagt tcagaaaact gagcaggctt aactcctaga
    25681 aaaatcacat ctgcttctgc aaacatttct tcattgctgg aagcctgacc accaaagtct
    25741 gcaatgaaag catctacctt agcttgacta cgattggcaa ggagaatctc atctgacgtc
    25801 ctagtctgca agacagattt tgccaagcta gcacccatat tccccaaacc gataaatcca
    25861 atcttcatct cttactccct tatctgccca tcaccggcaa ccacatactt gtagctggtc
    25921 aactctttca agcccatggg accacgcgcg tgcaatttct gagtagaaat ccccatttca
    25981 caaccaagac caaattgtcc tccatctgtg aaacgagttg aggcattaac atacaccgct
    26041 gcagagtcca cttgatctgt aaagtatgct gcagcttcag cattttccgt cacaatagca
    26101 tccgaatgat gggtgctgtg ggattcaatg tgcgcaaccg cttcttctaa actgctcaca
    26161 accttaacag caaggacata gtctaaaaac tcggtgtcaa agtcttgggt ctcagctgct
    26221 tgacctgaaa caaactggct tgctttgcta tccaagcgga attgaattgg ttccagtcca
    26281 gcttccttac gctctgcaac cagcatttga tccaagcgag gaaggatgct tgctgccttg
    26341 ttttcatgaa ccagcagaac ctccatggca ttacaaacag aaggacgact ggttttagca
    26401 ttgttgatga tagacagcgc cttgtcttcg tctgcatcct tatccacata gacatggaca
    26461 atcccagtcc ctgtctcgat aacaggtaca atcgcattct caaccactgc attgatcaag
    26521 ccagctcctc cacgaggaat gagaaggtct agatagccct tggccttcat catagcataa
    26581 ctactttcac ggctagtatc ctccaccagt tgaatcacat ttggatgaat agtagtcgtc
    26641 tccaagccct tcttcaaggc tgtgacaatg gcatgggttg tttgataggc atccttacca
    26701 ctacgaagaa caaccgcatt tccactctta agagtcaaag cagccgcatc agacgtcaca
    26761 tttggacggc tttcatagat aataccgatg acacctatag ctacacgttt ttttgtgata
    26821 accaaaccat tttcaagctg acttgtttct aaaacttcac cgattggatc tggtaaggca
    26881 accacttcac gaattcctct tgccatcgct tctatacgat ctgcatccaa ataaagacga
    26941 tccaacatca catctgagat tttcccctta gccgctgcca tatcgagggc attagccgct
    27001 aaaatttcct cagtagcagc cactaagtga tcagccatgg ctagcaaggc ttggtttttc
    27061 acttcttcac tagctgtgtt aatcgatttt ttaacagcct gtacctgttc aaattgttct
    27121 tgtctactca ccatagttta cctctaaaat tctgtaaaaa gtagttggat ttcaggagta
    27181 atggaaatcc agtcgtcacg gtaaatcaag acacccttgg ctttttgaga acgcaacata
    27241 tcctccaaag cagatgctcc aaattgcacg cgtccttttc caagtgattt tccactttcc
    27301 ttgtcaaata ctgtcacgat atcaccgtaa gaaaaggctc cttctgcttc aacgatacca
    27361 gataagagaa gactctttcc atgttgagag agagcttccg cagccccttt atcaacccaa
    27421 atagaacctt gactctgagc atagaaggca agccattgtt tctgggtacg aagccccttc
    27481 tcttgagcaa caaagtaaga accatcctcg gtctcctctg ccgcctcaat catggaatct
    27541 gatttcaagg atgagcagat ataaacagga actcctgatt ccgtcgcgat agttgcagcc
    27601 ttgattttgg ttaacatacc cccagttccg tttgacgaac cagctccacc agccatatca
    27661 ataatctcac gattgatggt ctcgattctc tccaagcgtt tggctcttgg atctgaatta
    27721 ggatttccag tatagagacc gtccacatct gtcaagaaaa ctaaaaggtc tgcttggacc
    27781 atcgccgcta cttgagcact tagagtgtca ttgtccccaa ccttgagctc atcaataacg
    27841 acactatcat tctcattgat gataggaatt gccccacggt tgagcaaaac cgacaaagcc
    27901 tgatgggcat ttttataacg acgcttatcc acaaagtcat cttgggtcag caagatttgt
    27961 gcagaaacga tttgacgcaa gagaagattg gtcgtatatt cttccaacaa aagtccctgc
    28021 cctaccgctg ctgaagcctg tttatcagca attttagtcg gacgcttttt aaatcctaag
    28081 gctccaaaac cagccgcaat ggcacctgaa gacaccaaaa tcaactcatg accagcctcg
    28141 tgcagcatag ccaactgctg ggtaatatcc tttaccttac tacgtgataa acttccatcc
    28201 tcatttgtca gagaagaagt acccacctta aagacaatcc gtttgtattt catagtctca
    28261 ctccgattat tcatatttat ccattataac atgaataaca ggaaatagaa aagagttgat
    28321 aggaaaaaga aggccctaaa accttctttt ctactactgt tctgattccg atttgtttac
    28381 actcgtttca gagctttgtg aagttgagga tgtcaaatct tgactagttg aaaaatttgt
    28441 aacactttca tgttgactcg tttctttatt ttcaagatcc tttttcacta cttctttgga
    28501 ttcttttatt tctgaatgac ttgtagtttt aattgtagca gatttctcga tcgaaacatc
    28561 cactaaccag gcaccacttg aatccacagt ataaccttct ggtgtcttac cgttcacaag
    28621 taattgacca ttttctttca agaagtacca tttatccttg tccttgatcc aacccacagc
    28681 tcgtgaaccg tctgtcttgt agaaatacca atcatttgcc tttttatgcc agccttgctt
    28741 catagctcct gaatcttcca gataataatg ttgaccagca acttctatct cacctgtctt
    28801 catgacacca gtagaatcca tatagtacca ggtttcttta tcttttaccc agcccatttt
    28861 catttcccct gatggagcaa agtaatacca ttgccccata tattgaagcc atcctgtctt
    28921 catagaacca tcaacatcca aataatacca ctgctcttta tcttgaatcc aaccaatttc
    28981 catctggttt tctttgttaa aataatacca gattccagcg attttcttcc aatttttagc
    29041 agaagcacca gagtctgtca aatagaacca atgattgttc cattttttcc attgattctg
    29101 taacaagata cccgtttggt taaagtaata ccattcacct tcgatttcat tccaaccgac
    29161 agcatactct cctgtagaat caggcgcttg ataccaccag ttcccatatg cactcttatg
    29221 ccaaccagct tgaaaacttg gaatcggctt gtaggatgtt gaaatattga caaaaccgtc
    29281 ttttcgaata tcaaaaactg ttgcatcata gtctttgctg gctgcgttga ttctctcaat
    29341 tcctcgttct ttgagccaat taacatactc actatcaaca ccatttttcc aaggtagact
    29401 atccgaagtt tgaacaatca aactcggact caaattttta atgaaatcct tggtatttga
    29461 tttgttggta tcatggtgat gattaaactt catcaaatca acttttccaa tgagaggacc
    29521 atacttgtct tctgctccat gaacattatc taaatcgccc ccaaggtaaa ttttcttgcc
    29581 attgactttc accacgctaa tcaaggaatt ggaattgtca tcccaaattt tctttaattc
    29641 acccgatgaa tcagtttcat tttcataatt atagagctga atatccatgt ccccaaactg
    29701 aaaatgagca tccccttgtg tgatattttg aataactgaa acaccttttt ctgcagcagt
    29761 ctgtaaaacc ttatcatagc catacagatt atcccataga cgttcagaat tagtaatacg
    29821 actatcacta tatttcttaa gatagactcg gtcaactgga taggtagaca gtaattcatc
    29881 aacatttcca atatgatcac tgtgggtatg ggtcaccaaa ataaaatcaa gtttttggac
    29941 acccaattcc ttcaaacgac gaaagacacg gtctgttaga acatgcttat aagacgtttc
    30001 aattccttct ctccatggat agcgagaatc acttccatct gggaaatcat aatcttctcc
    30061 tgtatccacc atggcaaaat gtccattgct ttcaagaata atcgcatcac tgccaccttc
    30121 ttgaacattg ataaagtgga ttttatttcc tgaactttct tgagcctgaa cattcccata
    30181 ccatgacaaa cctaaaaaag cgcctacaag tgctaaacta gttaatttct ttttcattct
    30241 tactttctca atctctccaa ggtttcctta aaaatctctg ggatatctgc tttaaattcc
    30301 aaggtcttac ctgttctcgg atgagtaaaa cctaaagtct tggcatgaag aaattgtcca
    30361 tgtcctttca aagtcttgcg aggaccatag acctcatcac cagcgactgg atggccgata
    30421 taagccatgt ggacacggat ttgatgagtg cgccctgtct ccagttgcaa ctctactaag
    30481 ctataatcgc caaagcgttc caagacgtga aaacgcgtca ctgcaggctt ccctttagca
    30541 gttacagcct gtttcttacg gtctttttca ctccggccaa tcggcgcttc aattacacca
    30601 cgatcattag gtagatttcc atgaacaatc gcccaatatt tgcggagaga ctttttatcc
    30661 ttgagttctt gggcaagtgc tagatgcgca tcatcgtttt tagcaatcat gagaagacct
    30721 gacgtatcct tatcaatacg gtgaacaatc cctggacgca gaaccccatt gatacccgac
    30781 aagtccttaa tatgatacat gagggcattt actagggttc cactggtatg accagcactc
    30841 gggtgcacaa ccattccctg aggtttgtta acgacagcca catcctcatc ttggtagact
    30901 atttctagcg gaagatcctc agccacatac tctaatacct ctggttctgg cacatggtaa
    30961 gtgacgacat caccctcttg gactgtgtat ttagctttct tgacttgacc attgaccaag
    31021 acctggcctg atttaatttg ttcattcgcg agactacgtg ataattctga caaatctgac
    31081 aaagccttat ccaaacgcag accaccagtt tcaattttaa tttccattta tttcctcttt
    31141 tagcattgca atcaataaaa taatcactcc aaccgtcaga tagctatctg ccacattgaa
    31201 aattgcaaag ttgataaagt caaggtggaa catatccaca acaaagccct gactgaccct
    31261 gtcaataaag tttccaagac cacccgcgat tattagagtc aaacccaaga ccatccagaa
    31321 tgagtcctcc atgtgtttat gtaaatacca aatggcacct atcacgacaa ccagagtaat
    31381 gacagcgaat aacaactgct gatcttgtaa gatagaaaag gctgcacctc gattttgcag
    31441 gtaggtcaag ctaacgaaat tggggatcca ggagcgcact tcacccagtg gaatctgctg
    31501 gacgatatag gatttgacca actgatccag cccaatcaaa agcagtacaa tgactgccac
    31561 tattgctctt tttttcatga tttcctcttt tgatcaaaat attcttgcat gacttctacg
    31621 aagagagtcc cagcttgact aagctccact tcttcacgtt taacatagac catgcggtta
    31681 tctaggttat ccttgagacg aataactgta atgccattaa cactgtcact atctaaaaat
    31741 ccagaacctg tcgcataggc gtccgtccgc tccaaaatac cattcaaggt ggcacggtct
    31801 gtcacattaa acatctgtga gctagcgctg gtatcaacaa agttctctga ataataaagg
    31861 tactcgtctt tctcttgagt gaaacgaacc gttggtaaat ccgctaaatc ctccatgact
    31921 aattcctctt tctgggctaa aggatgaccc tcacagagat aaatatgggt atggaaagga
    31981 atcaattcga tgacctccag acctaacttt tcaacccgtt gcataatccc ctttttattt
    32041 tgattgttga ggtagataat cccaatctca ctatgccctt gcgccacttc atctaatatt
    32101 tgaacagtag ttgattcaaa aatacggaag ttcttatagt caggatagcg ctctgaaaag
    32161 gccgtaatag ttggtggtaa gaagtcatag tgctggctag caacggaaaa ttcatctttt
    32221 tcttcttcag gattggcata ctgattttga aaaatatcaa atcctttaac caattcttgc
    32281 gctttttcat aaaattccat cccacgacgg gtcaagaaag tccctgagct ggtccgacgg
    32341 aaaatcttaa aacccaactc tttttccaaa tcccgaacag aaatagacag actcggctga
    32401 ctaacataca tcttttcagc agcttcacga aaagtaccac tattggcaat agccacaaca
    32461 tagcgtaatt gttgaatgtt catcttctac ccctaacttc tttatctttt cattatacca
    32521 tattttagaa gttttccaaa aaggaaaaaa gaacatccta ttcttcttaa ctatcttcac
    32581 tatctgcctt tctcacgcca atcttatttt caaaatcaat tcaaaaaaat aagtggctac
    32641 acaccacttc agtatcggaa agaaaaacgt tgactatttg tgaaaaaaga aaatgccgga
    32701 aaattccgac atttttttag taagctaact tcctgaaaat aggagtaacc aaacatccca
    32761 gaaggcagtg atattgatga gaatatgaac tagtattgga tagtagagat ttttagtcat
    32821 gcgatacaat agagctaaaa tcagacctcc actagcataa atgaaaaaag caagaggagt
    32881 taaagcaaaa ttgatatgaa tataaccgaa aataatagca gaaagcaaaa catctccgta
    32941 ccaaggtgag tttttgaaaa aggttgtcat aagcacacct cgataaatca attcctcagc
    33001 aataggggcg atgaagcaaa cgatgagcaa gaaataaggg aactcctgtc tccccatcat
    33061 ttctatcgtt tcattcaaag aaatctgatt tgaagacagg gatatgaaat acgaaaagag
    33121 gaagtcagac atatatgaaa tgatgtagcc cagtaaaagg tagatgaagt acctcagctg
    33181 ccacttgaaa tgaaaaattt tctttcctgc aaaaaccagt agatagatga ccgctaagaa
    33241 aagaactccg ctctccatca aaagcagaat ctgaaaaaat tcacgacttg ctggtagata
    33301 gggctttgcg aggtgattga aaactctcca aaaccaagtt gatttgtaaa aaattaagga
    33361 caatgctagt aaaatttgaa tagcccgttt tttcatatta aattctctgc tttctcccct
    33421 tgtttcttca tattactaat aaattttact taaaatctcg cagcacttcc tttgcaaaga
    33481 tgattgcctc ctccaatata tcctaaatca taggtgcctc tgggacaaaa tccatgaacc
    33541 ggcagagtta atactggttc tatttcccaa tcgtacctac cattaggatt tttaccatat
    33601 gaatctgctc caccttgtat cagctctaat tcttcatttg ttagatttat attttttgtc
    33661 attaaaatca tgatatattt cctccattat tcttcagatt agttgagtaa tctgatactc
    33721 atacctactt acaaaaaaac tattatatta agttggtttt ttaatttgtc tagttgcaac
    33781 attgacaaac atagtatagc atatctttgc gaaatatcct cttcaaatca tgaattgtca
    33841 tcaaaacatc ttaaactata aaatcaatta gtctcaagct ttctatcaat ttcttctcca
    33901 aaatatgcta taataatagc aaaagataaa gaaggaagac ctatgattaa actactagcc
    33961 ttggatatgg acggcaccct cctcaatgaa gccaaggaaa tcccacaagc tcacattact
    34021 gctattcaca aagccattga aaaaggtgtc aaactggttc tctgtacggg tcgccccctt
    34081 ttcggtgtcc tcccctacta caaaaaactg ggactcgacc tccagaatga gtatgtgatt
    34141 gttaacaacg gttgttcaac tcaccagact agcgactggg gcttggttga ctggcaagaa
    34201 cttagtccag ctgacatcga atacctctat gaccttgctg aaaagagtga tgttcagttg
    34261 acactttttg acgagtcaca ttattttgtt ctcggtggaa agcccaatca agttattgaa
    34321 aatgatgcta aactagtatt ttcagacctg actgaaattt ctcttgagga agcgactagt
    34381 ggaaagttcc ggatgttcca aggtatgttt ttaggaacaa aagaacaaac agacgatttt
    34441 gagcagcgtt ttgctgaaga gctttgccaa cgattcagtg gagttcgttc gcagcctgtc
    34501 atttatgaag caatgccact tggaacgaca aaggctactg ctctttcacg actagctgag
    34561 attttgaaga ttgattcctc agagattatg gccatgggcg atgctaataa cgatatcgaa
    34621 atgctccagt ttgcagggct tgggattgca atgggaaatg ccagcgatta tgtcaaatct
    34681 cttgcggatg ccgttacctc aagcaacgaa gaagacggcg ttgcgcgtgc tattgagaaa
    34741 tatattctat aaaaaagaaa agcaaataga cagaagttac tgctatttgc ttttttgcta
    34801 atattttaaa atacggacta atcaatagag aagaatagcg aatcataaaa atcgatttac
    34861 tagatgccat agtatcttat agttgctaat aagaagttag tctagcagaa tgaatctctc
    34921 atttctccca cactaatctg taatttgtct atacatttct ggtcttctat ctcgaaacaa
    34981 gccccagttt aggcgttcac ttgctccctt gtctaggtta taagtagcta acagaacagc
    35041 ttcttcttgt ctttcagctc gttctagaat agctcctgtt tcatccgtca taaaggagga
    35101 accgtagaag tcaagactgg aactctgtcc gccattttcc tcactaggag taacctcctc
    35161 taaaccataa cgattggctg cgatgactgg aacaatattc gctgctgcgt gcccttgcat
    35221 agtacgttgc cagtgaccac aactatctgt atccaaaatc ggctctgaac cgatggctgt
    35281 tggataaaag agcaattcag caccattcaa tgcaagacag cgcgctgttt cagggaacca
    35341 ttgatcccaa cagataccga taccaatctt agcatagcga gtattccaga ccttgaaacc
    35401 agtgttacca ggcgtgaaat agaatttttc ttgataataa tggtcatctg gtatgtgggt
    35461 ctttcgataa acgcccagca cttccccatc tgcatcaatg acggcaatag agttatacaa
    35521 gacattacca tctttttcat agaaactgat tggtaaaaca acttgtagtt ccttagcaat
    35581 caccttaaaa tgctgaatgg cagtattttc cgctacagat tgggcatact ggtagtagtc
    35641 atactgacgt tcctgacaga aatagggatg ttcaaacaac tcgggcaaga gaataatttg
    35701 ggctccttgc tcagcagcct gacgtactaa acgctctgcg gtttggatat ttgttgccac
    35761 atccttagcg cattgcatct gaatggttgc aactcttaca tttctcatct ttttctccta
    35821 ttctggaatt tgttgggtga tacagtggat attgccacca cctaagagaa tatctctggc
    35881 tggtattccg acaactttac ggtctgggaa acacttgctg aggatatcta aggccacttg
    35941 gtcgtttaca tcctcaaact gtggaaccaa gacagccttg ttggcgatat aaaagtttac
    36001 gtaggaagct gctagtcgtt cacctgcgta tcgcttttct tctccttctt catagatgta
    36061 gcctggcaaa tcttcttctg tcacaacttg tcgaactgca gggataggca atttatgaat
    36121 ggtgaagtga caaccttttg catctgtttc ctgttctaag agttcgagat ctgcttttga
    36181 catggcatac tggggatcat tttcgtcatc tgtccaagcc aaaacaagct cagcaggacc
    36241 aacaaaggca gcaacattat cgacgtgttc attggtttca tcctgataaa taccataagg
    36301 aagccaaata actttttcag caccaagact ttctaataat gtgttttcaa tctcctcttt
    36361 agtcaggtta ggattgcgac caggactaag caagcaactt tcagttacga gaatagttcc
    36421 ttgaccatcg ctatggattg cgcctccttc cagtacaaaa ggtttagcat catagacagg
    36481 cctttccaag gcctcagcaa aacgactggc tacttggtca tcctcttcat aatcttgata
    36541 aagaccatca taggtgcctc cccaagcatt aaaggcccaa tccacggcta atttcttacc
    36601 tttatcattg acgagaatgg ttgggccagt atcacgcgcc caggcatcat tggtgggaat
    36661 gtctaaataa acaaccttgt ctccaagata ggattgggct tcagatagat aggcctgctc
    36721 caccaaaaga tagactcttt ccccttctgc tatggtctcg atgatctgag taaatgctct
    36781 tttagcagcc tttccttgaa aaggccatga tcctggtcga gtcggccata tcatgagggt
    36841 accatgatgg ggttcgtact ctgctggcat gtgatagcct aatttttttg gactgtccat
    36901 catgataatc tccctttaaa gtcttgatag ccaaaagctt tgagtaagct acagtctccc
    36961 tgttcgtcca tgagatagag acttggcaat ccaataccat taaaggtatt atttttgaca
    37021 aaagaataaa tggccatgtc ttgaaaataa agtctgtctc cgatttggac tggattttca
    37081 aaactataat caccaatcac atcgcccgtc agacaggtat tagaagaaag tctgtaggta
    37141 tgggcttttt cctgtgactc aaagccattt ctcaaaggtg gacgataggg catctcaagt
    37201 acatcaggca tatggcaggt cgcagaggcg tctaaaacca agatttccat accgttttct
    37261 acaatatcta atacctcagt tgctaaataa cccgcattaa gcgcaatggc ttcaccaggc
    37321 tcgatataga tttcaagatt gtaagttttt cggatacgct tgatttctga aatcagcaaa
    37381 tccacatcgt aaccttctct tgtaatatga tgaccaccac ccatattgag ccattttacc
    37441 tcatgtaagt agggaccaaa ctgttcttct actgctttca aagttgtttg taaatcatct
    37501 gctccctgct cgcaaagggt atgaaaatga agtccgtcaa ccaaatctag caaatcactc
    37561 ggaatcttgt ctatagtaac tccaaagcga gaacctggtg cacaagggtc atagagcgcg
    37621 tgatctcctt gagttgaaca ctgagggttg aggcgcaaac caacactgac accagcctct
    37681 cgacaacgcg gaccgtgttt acgcaactgt ctctctgagt taaagacgat atggtccatt
    37741 atctctagca attcctccaa gtctgcatcc ttgaaagcag gcgcaaatac atggacttca
    37801 ccaggaaatt cttcccttgc caatttggcc tcatagagtc cactagctgt cgtacctgat
    37861 agatactggc taatcaaggg ataagttttg tagagggaat atgccttctg ggcaagcaag
    37921 accttgcaac cggcctcttc ttgtacatat tgtagaatgc ggcaattagc ttctaacttg
    37981 gccaagtcaa taacataggc tggtgttggt acttgttcta acttcattag tccaccattt
    38041 gtggattttc aaccacaacc catggcaaac catactcatt caaagcttcc atgaatggat
    38101 ctggatctaa ctcctcaagg ttatacactc cagcttgttt ccaagttccg ttcatgacta
    38161 attttgtccc aatcatggct ggaactcctg tcgtataaga aatagcttgc gaaccaacct
    38221 ctgcgtaaca ttcctgatgg tcgcagacat tgtagatata gatagtcttt ttgacaccgt
    38281 ctttgacacc tgtaaagata catccaatat tggtttttcc gactgtacgt ggcccaagac
    38341 tggcaggatc tggaagcaag gctttcaaaa attgaattgg aacaatttct tggccgttaa
    38401 agttaatggt atccgtacga aggagtccaa cattttcaag acatttcatg tgcgtcaagt
    38461 aagattgacc aaaagtcata aagaaacgaa tgcgtttgac acctggaatg ttcttggcca
    38521 atgattcgat ttcttcatgg tgaaggagat acatatcttt ttgtccaact tgagggaaat
    38581 catactcacg cttgatagac atagcttcga cttcgaccca tttcccatct tcccagtaag
    38641 aacctggcgc agaaacctca cggagattaa tttctggatt aaagttggtt gcaaatggat
    38701 aaccgtggtc accgccatta cagtctaaaa tgtcgatata atggatttca tcaaaatagt
    38761 gtttgagggc ataagctgaa aagacactag ttacacctgg gtcaaaacca gaaccaagaa
    38821 gagcagtcaa gcctgcttct ttgaatttct cttgataagc ccactgccat gagtagtcaa
    38881 agtaggctgt aaaaccaagt tccttacaac gtttttcgta gatagcacgc cactcagggt
    38941 cttctgtgtc ttctgcttcg tagttggctg tatcgatata gtgaacacct gttgccaaac
    39001 aagcatccat aatggttaaa tcttgataag gcagagctac attcaaaaca gcttctggtt
    39061 tgtagctttc aatcagggca atcacttctt caaccttgtc agcatcaagt gctgcagttt
    39121 caattttagt acttgttttg ccttctagct tcgctttcaa gtcatcgcat tttgacttgg
    39181 tacggctagc aatcataatc tctgtaaatg tttcgctatc ttgacaaatc tttgaaatag
    39241 caacttgggc aacgccccca caaccaataa ctagtaaacg actcattttt ttccttcctc
    39301 ttcttctaaa atgtcctcaa catacttggg caacataaag gctcccacgt gtaagtttgc
    39361 agtgtagtat tctgtgaaaa gctggcgttt tttccagcct tccttgtcaa aatctttgac
    39421 agggtggtat tttttcgatg caaatccaaa caaccaatag ccagctgggc tagttggaat
    39481 atgggcctga taaacccgac tgattggaaa ggcttgattg accttgcggt gcatgcttcg
    39541 gcaggccgac tcatcctcgt caaagaaggg actcccatgc tggtaaatca tgatgccgtc
    39601 ttccttcaga gctcgataac tattgccgta gaattccttg gtaaagagtc cttccgtatg
    39661 gccaaatgga tctgtcgcat cgttgatgat aatatcgtaa tcatcttcgc agtttcgcaa
    39721 aaagcgtagc ccattttggt agtaaatggt aacacgagga tcatctagcc ctgcagcaaa
    39781 gtctgggaaa tactcacgac agacctcgac caacatctca tccggttcca caatatcaat
    39841 ttgctccagt tcaggataga gggttaatac ttgggcaaca ccgccgtcac cacccccaat
    39901 aaccaatact ttctttggat ttgggtggac agccatggga acgtgaacgg tcatttcatt
    39961 gtagacgaaa tcatccgcat ctgagaacaa gacatggcca tttaaaatca gtattttccc
    40021 aaaagctggc gtatccaaga cttcgatatc ctgccattca ctttttccag cgtaaagttg
    40081 cttggctgtt ctcagagaca atttgacatc tggagtatga acttcagaaa accataaatc
    40141 catctatttc tccttatatt atatttagcg cagttagcta ctgccaaagc ccaagtggta
    40201 tacttggaat aagccactgt ggattagttc atttcctcca atcgcttgac gatttccgaa
    40261 aggctctaac cacagctttt gtttcaattg gtaatgagtt tgataacgca tagacgtttt
    40321 atctcgtcta aggtaacaag gcaaaaagtt cgtggataac caagtagact tgaaatacta
    40381 catctggagg tactcccatg ctttatgtgg gcattgatat cgctaaaaat aaacacgatg
    40441 ttacagcctt gaatgttcaa ggaaaaactg ttcttaaacc actcactttt tcaaataata
    40501 aagctggttt tgaactctta gatctgtctc ttcgacagct caaccaagac tgtctcatcg
    40561 ctcttgaaga tactggacat tatgccttta atctactgaa cttcctgcat gaacaaggat
    40621 ataaagttta cacctacaat cctttgctca tcaaggaatt tgccaaatca ttatcacttc
    40681 gcaagactaa aacggataag aaagacgctc atggcatcgc tcttaaactt ctttctgacc
    40741 ccaatcgtga acaatttcaa cacgataatc ggcaagtaga actaaaaata ctggctagac
    40801 atattcatcg tctcaagaaa aacagtctga ttggaaagta caatacactc gttgtcttga
    40861 tatcatcttt cctgagttgg ataaaatcgt tggaaagcat tcagaatata cctaccaact
    40921 cttgacacgc taccctaatc ctcagaaaag gattgaggca ggatttgata agctgataga
    40981 aattaagcga ttgaccgctt ctaattcaag ggctttttgc cgtgctctaa aatcatcgcc
    41041 aaatcatcaa attgaaataa gaaatagttt agataaaact attgactttt cttatagttt
    41101 gtctttctct taataacgtt gatatgattg acctctggat cttccgtccc ttggagggag
    41161 caaccacgtt ccttggcgaa ttggatatag tctacaattt ctcgtgtaat gcgttcacca
    41221 ggagccaaga taggaatccc tggaggatag cacatgacaa attctccaca gacctgtcca
    41281 acagactcat ctaaggtcaa actttttctc tctgaataga aggcttcttg tggagacagc
    41341 accaactcgg gctgaatata ttctccagct attaagtcct tcccatctcg tgaatagagt
    41401 ctcttaatat cagccagagc accaaccaag cgctcgatgt cttggatgcg gtcgccgatg
    41461 gaaatatagg ccaagatatt gccgatatca ccaaactcga tctgaatgtc gtattcgtct
    41521 cgcaagaggt cataaacctc gatacctgtt aagcctattc cctgagtgta aactgacaac
    41581 ttggttacat caaaatcaca gaccgacaca ccatctatta actcttttga gtaagcatag
    41641 taaccgccaa tggcattgat ttcatgacga gcgtactcgg atagctcaat gacttcctca
    41701 aacgactctt taccacgaag ggccaagttg cgacgtgaaa tatccaaact agccatcaat
    41761 aagtaagagg cagatgtaga ctgggtcagg tttataatct gacgaacgta ctcgggattc
    41821 atctgctccc cgattaaaag aagcgaactt tgtgtcaaac tcccaccaga cttatgcatg
    41881 gaaactgctg ccatatcagc tcctgcatcc atagcagaaa ttggaagttt accagtgaaa
    41941 tgcaaatgcg ctccatgggc ttcatctact aaaaccatca tgccagcttc atgagccatt
    42001 tctgtcaacc cctttaggtc tgaacagatg ccgtagtaag taggattgtt gattaggata
    42061 gccttagcat ctggatggtc ctttatggcc tgtgctactc ggtcattttc aagacctaaa
    42121 gcgataccaa tcttaggatc tacactcatc tcgatataga tgggaatggc accacataga
    42181 accaacgcat tgatagcaga tttatggaca tttcgtggca gaataatctt atctcctgcc
    42241 ttgcaggttg ccagaatcat agtctgcacc gatgaagttg ttccaccaat cattagaaag
    42301 gcatggctag ctccaaaagc atctgcagcc agctcctctg catcacgaat aatcgaaata
    42361 ggatggccta aattatccaa gggtttcatc gaattgacat caatgcctac acatttttct
    42421 cctaagagtt cgacaagttc tggatttccc cgtccacgct tgtgacctgg aacatcaaag
    42481 ggaacaatcc ttttcttgcg taacttcacc aaggcttcat aaattggggc ttggttttga
    42541 tctaactctt tcaaaacata ctcctttcaa tatttttagg accttatgaa aactaaggaa
    42601 ctaaaggttg actcatgaaa aaagagcagg ttttcacctg ctctgcaatc ttctgacgtg
    42661 tttattttgg tttctgttga gtatgtctgt tcccgatgtt tcctaactct ctagtagcaa
    42721 atattacgta ctttattgat cgtttcacaa gatgacgtgt gctttcacca cactaaaaat
    42781 ttatgaatta ggacaagtgt cctaacatca acttataaaa gtaggctttt aaccctatca
    42841 ataatgtggc ttttcaacca cgcttcggca ttcaaccctg cctgtccgta ggcatttttt
    42901 actcgggttt atatttgcta gaaaacatca tctcattttc taagctttat tactatatca
    42961 tgtttttaag aacttgtaaa gtattttttg ataaaaaaca aaaatatagt agattgaaac
    43021 tagaatagta cacttctgct tctaaaacat tattagaaat agattttact gtcctgatcg
    43081 atttgttctg ttcttgtttc attttactat atgttcgtaa atgaaagttc tataatgaag
    43141 ttagccaccc agccctccta aaaattagat ggttcaacta gctga
//
LOCUS       DAVLHM010000017        40284 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLHM010000017 DAVLHM010000000
VERSION     DAVLHM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.017"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            19..89
                     /locus_tag="VXE45_000929"
     tRNA            19..89
                     /locus_tag="VXE45_000929"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51..53,aa:Gly,seq:tcc)
     gene            124..197
                     /locus_tag="VXE45_000930"
     tRNA            124..197
                     /locus_tag="VXE45_000930"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:158..160,aa:Ile,seq:gat)
     gene            280..369
                     /locus_tag="VXE45_000931"
     tRNA            280..369
                     /locus_tag="VXE45_000931"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:316..318,aa:Ser,seq:tga)
     gene            380..453
                     /locus_tag="VXE45_000932"
     tRNA            380..453
                     /locus_tag="VXE45_000932"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:414..416,aa:Met,seq:cat)
     gene            457..529
                     /locus_tag="VXE45_000933"
     tRNA            457..529
                     /locus_tag="VXE45_000933"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:490..492,aa:Phe,seq:gaa)
     gene            542..622
                     /locus_tag="VXE45_000934"
     tRNA            542..622
                     /locus_tag="VXE45_000934"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:576..578,aa:Tyr,seq:gta)
     gene            627..697
                     /locus_tag="VXE45_000935"
     tRNA            627..697
                     /locus_tag="VXE45_000935"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:659..661,aa:Trp,seq:cca)
     gene            712..784
                     /locus_tag="VXE45_000936"
     tRNA            712..784
                     /locus_tag="VXE45_000936"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:745..747,aa:His,seq:gtg)
     gene            795..866
                     /locus_tag="VXE45_000937"
     tRNA            795..866
                     /locus_tag="VXE45_000937"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:Gln,seq:ttg)
     gene            876..959
                     /locus_tag="VXE45_000938"
     tRNA            876..959
                     /locus_tag="VXE45_000938"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:910..912,aa:Leu,seq:caa)
     gene            1066..2343
                     /locus_tag="VXE45_000939"
     CDS             1066..2343
                     /locus_tag="VXE45_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0788987.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2419..3903
                     /locus_tag="VXE45_000940"
     CDS             2419..3903
                     /locus_tag="VXE45_000940"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0788988.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3964..5244
                     /locus_tag="VXE45_000941"
     CDS             3964..5244
                     /locus_tag="VXE45_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0788989.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5248..5868
                     /locus_tag="VXE45_000942"
     CDS             5248..5868
                     /locus_tag="VXE45_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0788990.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6034..7176
                     /locus_tag="VXE45_000943"
     CDS             6034..7176
                     /locus_tag="VXE45_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0788991.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7582..7920
                     /locus_tag="VXE45_000944"
     CDS             7582..7920
                     /locus_tag="VXE45_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0788992.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7931..8289
                     /locus_tag="VXE45_000945"
                     /pseudo
     CDS             7931..8289
                     /locus_tag="VXE45_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8396..9013
                     /gene="pcp"
                     /locus_tag="VXE45_000946"
                     /pseudo
     CDS             8396..9013
                     /gene="pcp"
                     /locus_tag="VXE45_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9041..9898)
                     /locus_tag="VXE45_000947"
     CDS             complement(9041..9898)
                     /locus_tag="VXE45_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0788993.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVFFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10028..11170
                     /gene="tgt"
                     /locus_tag="VXE45_000948"
     CDS             10028..11170
                     /gene="tgt"
                     /locus_tag="VXE45_000948"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0788994.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11268..13085
                     /locus_tag="VXE45_000949"
     CDS             11268..13085
                     /locus_tag="VXE45_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0788995.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTV
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13238..14389
                     /gene="nagA"
                     /locus_tag="VXE45_000950"
     CDS             13238..14389
                     /gene="nagA"
                     /locus_tag="VXE45_000950"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0788996.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14552..15610
                     /locus_tag="VXE45_000951"
     CDS             14552..15610
                     /locus_tag="VXE45_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0788997.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15761..16126
                     /locus_tag="VXE45_000952"
     CDS             15761..16126
                     /locus_tag="VXE45_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0788998.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16202..17143
                     /locus_tag="VXE45_000953"
     CDS             16202..17143
                     /locus_tag="VXE45_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0788999.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17091..18107
                     /locus_tag="VXE45_000954"
     CDS             17091..18107
                     /locus_tag="VXE45_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0789000.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18109..18435
                     /gene="comGC"
                     /locus_tag="VXE45_000955"
     CDS             18109..18435
                     /gene="comGC"
                     /locus_tag="VXE45_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV0789001.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            18404..18832
                     /locus_tag="VXE45_000956"
     CDS             18404..18832
                     /locus_tag="VXE45_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0789002.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSIIF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18837..19097
                     /locus_tag="VXE45_000957"
     CDS             18837..19097
                     /locus_tag="VXE45_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789003.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQININGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19060..19521
                     /locus_tag="VXE45_000958"
     CDS             19060..19521
                     /locus_tag="VXE45_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0789004.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS"
     gene            19499..19912
                     /locus_tag="VXE45_000959"
     CDS             19499..19912
                     /locus_tag="VXE45_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0789005.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20049..20636
                     /locus_tag="VXE45_000960"
     CDS             20049..20636
                     /locus_tag="VXE45_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0789006.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQAHLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20697..21650
                     /locus_tag="VXE45_000961"
     CDS             20697..21650
                     /locus_tag="VXE45_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0789007.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVELFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21701..22891
                     /locus_tag="VXE45_000962"
     CDS             21701..22891
                     /locus_tag="VXE45_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0789008.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23040..23411
                     /gene="rnpA"
                     /locus_tag="VXE45_000963"
     CDS             23040..23411
                     /gene="rnpA"
                     /locus_tag="VXE45_000963"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0789009.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23386..24210
                     /locus_tag="VXE45_000964"
     CDS             23386..24210
                     /locus_tag="VXE45_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0789010.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24229..25215
                     /locus_tag="VXE45_000965"
     CDS             24229..25215
                     /locus_tag="VXE45_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0789011.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25266..25889
                     /locus_tag="VXE45_000966"
     CDS             25266..25889
                     /locus_tag="VXE45_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0789012.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26020..27477
                     /locus_tag="VXE45_000967"
     CDS             26020..27477
                     /locus_tag="VXE45_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0789013.1"
                     /translation="MEVISSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27500..27781
                     /locus_tag="VXE45_000968"
     CDS             27500..27781
                     /locus_tag="VXE45_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0789014.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27858..28343
                     /locus_tag="VXE45_000969"
     CDS             27858..28343
                     /locus_tag="VXE45_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0789015.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28360..29025
                     /locus_tag="VXE45_000970"
     CDS             28360..29025
                     /locus_tag="VXE45_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0789016.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29029..29892
                     /locus_tag="VXE45_000971"
     CDS             29029..29892
                     /locus_tag="VXE45_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0789017.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29894..30598
                     /locus_tag="VXE45_000972"
     CDS             29894..30598
                     /locus_tag="VXE45_000972"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0789018.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIIVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30777..32450
                     /locus_tag="VXE45_000973"
     CDS             30777..32450
                     /locus_tag="VXE45_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0789019.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32562..33653
                     /gene="ulaG"
                     /locus_tag="VXE45_000974"
     CDS             32562..33653
                     /gene="ulaG"
                     /locus_tag="VXE45_000974"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0789020.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33767..35743
                     /gene="tkt"
                     /locus_tag="VXE45_000975"
     CDS             33767..35743
                     /gene="tkt"
                     /locus_tag="VXE45_000975"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0789021.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35860..36159
                     /gene="yajC"
                     /locus_tag="VXE45_000976"
     CDS             35860..36159
                     /gene="yajC"
                     /locus_tag="VXE45_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0789022.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36206..36634
                     /locus_tag="VXE45_000977"
     CDS             36206..36634
                     /locus_tag="VXE45_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0789023.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEILYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36636..37046
                     /locus_tag="VXE45_000978"
     CDS             36636..37046
                     /locus_tag="VXE45_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789024.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37347..39998
                     /gene="adhE"
                     /locus_tag="VXE45_000979"
                     /gene_synonym="adhC"
     CDS             37347..39998
                     /gene="adhE"
                     /locus_tag="VXE45_000979"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0789025.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12217 a         7208 c         9079 g        11780 t
ORIGIN      
        1 ccgttaactc ccattttagc gggtgtagtt tagtggtaaa actacagcct tccaagctgt
       61 tgtcgcgagt tcgattctcg tcacccgctt tgaactttgt tctttgtacc aagtttttga
      121 cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg tcggtggttc
      181 gagtccactc gtgcccatag tgtttagtcc attactaggg gattggaata ttatctgttc
      241 actaagagga cacgggcttg ttcccgtata aactattttg gaggattacc caagtccggc
      301 tgaagggaac ggtcttgaaa accgtcaggc gtgtaaaagc gtgcgtgggt tcgaatccca
      361 catcctcctt ttatattaac gcgggatgga gcagctcggt agctcgtcgg gctcataacc
      421 cgaaggtcgt aggttcaaat cctgctcccg caataaggct cggtagctca gttggtagag
      481 caatggattg aagctccatg tgtcggcggt tcgattccgt ctcgcgccat ttatatattt
      541 tggaagggta gcgaagaggc taaacgcggc ggactgtaaa tccgctcctt cgggttcggg
      601 ggttcgaatc cctccccttc cattttacgg gcatagttta aaggtagaac taaggtctcc
      661 aaaaccttca gtgtgggttc aattcctact gcccgtgtta atagaattat ggcgggtgtg
      721 gtgaagtggt taacacacca gattgtggct ctggcatgcg tgggttcgat ccccatcact
      781 cgcctatttt atattggggt atagccaagc ggtaaggcaa gggactttga ctccctcatg
      841 cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa ttggcagacg
      901 cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg ccgccggtat
      961 agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt ttggtataat
     1021 tatagttatt caaattttgt ttagattgag aaagtgtagg gtagtatgtc ttgttctatc
     1081 gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt gtttgtcgga
     1141 attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt tgaagttata
     1201 aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa ggtagatgat
     1261 tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt atttgaagtt
     1321 tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga ggtcgaaaat
     1381 cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa tcatgctatt
     1441 gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt ggcttatcca
     1501 cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa atcagattta
     1561 catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct ggatatttca
     1621 aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc taaggcttat
     1681 ttatttgcaa actctgaatt ttcgggtgcg gattgggata cgaaaatttc aagggatatt
     1741 ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa tgctagactc
     1801 cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt tactgcggaa
     1861 cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt ggctacgcct
     1921 gaaatccaag catttgctct gaatggggat gaggttatta tttcccccca agagaaggat
     1981 tttgaaactc atcgtagtta ccagtaccaa gacttaacga ctcgaggaac agttgagttt
     2041 cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt tcacttggga
     2101 ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt ctttaaagta
     2161 tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct tacagatgag
     2221 gaagaaacta cgattattga attttccaaa gacttactcc tactagctga ggagggacta
     2281 gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga attgagccta
     2341 taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga cgagactata
     2401 gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc caacaataca
     2461 gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt gtttacaccg
     2521 gttacttatc caaaggtaga tttggacttt gacaaattga aagatgcttc ttaccaggaa
     2581 gttgctaagc tagttttgtc agcattttta gatgacttta cagctgagga gttggactac
     2641 tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcact attagtgaaa
     2701 ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt taaggatatg
     2761 gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg tttggagaac
     2821 aagattgtta tattgacagc gacatctggt gacacgggga aagctgctat ggcggggttt
     2881 gcggatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt cagcaagatt
     2941 caagagttac aaatgaccac tcagactggc gacaatactc atgttattgc tattgatggt
     3001 aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgatgtggc tcttcgtgaa
     3061 aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat tggtcgtctg
     3121 gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac tggtgaaatt
     3181 gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa tatcttggct
     3241 gccttttatg ccaaacaaat tggtttgcca gttggtaaat tgatctgtgc ttcaaatgac
     3301 aacaatgttt tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg tgagtttaag
     3361 gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg cttgattttc
     3421 catcttttgg gaaataatgc tgaaaagaca gctgaactca tgaatgcttt gaacatgcaa
     3481 ggacaatata agttgacaga ctttgatgca gagattctgg agctctttgc agctgaatat
     3541 gcgactgagg aagaaacagc ggcagaaatc aagcgtgttt atgagttaga ttcttatatt
     3601 gaggatccac atacggcggt tgcctcagca gtttatagaa aataccaagc ggttactgat
     3661 gatgcgacta agacagtgat tgcttcaaca gctagtccct acaagttccc agtagttgca
     3721 gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc tcaattacat
     3781 gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgagacagc tcctgttcgt
     3841 cacaagacaa ctgtagcggc tgctgatatg caagcagcgg ttgaggctta tttaggactt
     3901 taagatagag ggagtaaact cggttgggaa accaactgag tttcttttca tcaggaggag
     3961 agattgttta agaaaaataa agacattctt aatattgcat tgccagctat gggtgaaaac
     4021 tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt aggattgata
     4081 gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc gattttcatc
     4141 gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa agaccagtcg
     4201 aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag tttcctttta
     4261 ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac ggagagggat
     4321 gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt tctcttaggt
     4381 ttaatgacta gtctgggagc cttgattcgt gcaacgcata atccacgtct gcctctctat
     4441 gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat ttttgttctg
     4501 gatatgggga tagctggtgt tgcttggggg acaattctgt ctcgtttggt tggtcttgtg
     4561 attttgtggt cacaattaaa actgccttat gggaagccaa cttttggttt agataaggaa
     4621 ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc tggagatgta
     4681 gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa tgcaatcgga
     4741 gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc aacggtcatg
     4801 ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt gagtaaacaa
     4861 accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata tgtcttgggt
     4921 gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag tgttctagtg
     4981 acactgtttt cactacttgg gacccctatg acgacaggaa cagtcatcta tacggcagtc
     5041 tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg catgtggtgt
     5101 atccgcattg ggacaggata tctgatgggg attgtgcttg gttggggctt gcctggtatt
     5161 tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta tcgttaccag
     5221 cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg ggatttagac
     5281 gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac ttttgctcag
     5341 ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta ttcggtgcaa
     5401 aatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct aaatcaggtg
     5461 cgtgcccaga gtctggctga gaaaaatgct caggtagttt tgatgccagg tgcgcgtgag
     5521 gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca taaggggaac
     5581 aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga gattttaacc
     5641 agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct gctagataag
     5701 tatcagttga attctgataa tacttattat ataggggatc ggactctgga tgtggaattt
     5761 gcccagaata gtgggattca aagtatcaac tttttagagt ctacttatga agggaatcac
     5821 aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata aaaagattgt
     5881 gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg ttacaaggaa
     5941 tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt gtgttatgat
     6001 agacaggtac taatttgaaa ggaatttgaa agaatgaaga aaagaatgtt attagcgtca
     6061 acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt tctttggact
     6121 gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa aacaagttat
     6181 accgtacagt atggtgatac cttgagcact attgcagaag ccttgggtgt agatgtcaca
     6241 gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga aactgttttg
     6301 acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac acctcaagca
     6361 gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca agtgaccgtt
     6421 gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagc tccaaaagaa
     6481 gtagcatcaa gttcagaagt tacaaagaca gtgattgctt ctgaagaagt ggcaccatct
     6541 acgggcactt ctgtcccaga ggagcaaacg gccgaaacaa gcagtgcagt tgcagaagaa
     6601 gctcctcagg aaacgactcc aggtgagaag caggaaacac aagcaagccc tcaagcagca
     6661 tcagcagtgg aagcaactac aacaagttca gaagcaaaag aagtagcatc atcaaatgga
     6721 gctacagcag cagtttctac ttatcaacca gaagagacga aaataatttc aacaacttac
     6781 gaggctccag ctgcgcccga ttatgctgga cttgcagtag caaaatctga aaatgcaggt
     6841 cttcaaccac aaacagctgc ctttaaagaa gaaattgcta acttgtttgg cattacatcc
     6901 tttagtggtt atcgtccagg agacagtgga gatcacggaa aaggtttggc tatcgatttt
     6961 atggtaccag aaagttcaga attaggggat aagattgcgg aatatgctat tcaaaacatg
     7021 gccagccgtg gcattagtta catcatctgg aaacaacgtt tctatgctcc attcgatagc
     7081 aaatatgggc cagctaacac ttggaatcca atgccagacc gtggtagtgt gacagaaaat
     7141 cactatgacc acgttcacgt ttcaatgaat ggataaaccc gacttggtaa catcattttg
     7201 acgaatgaga tctagctttc gtgataggaa gcgattctcg ttcgtttttt ctttgtcata
     7261 ctcttcgaaa atctcttcaa accacgtcag ttttatctga aacctcaaag ctgtgctttg
     7321 agcaacctgc gactagcttt ctagtttact ctttgatttt cattgagtat caatttgaat
     7381 ggaaaatgga aagttattat cttgtaataa tccaagcaac attcttgcaa tctattttac
     7441 tttatatcac aattgattgg tcaactattg ataagtcaat ggataggagg aagaaatgat
     7501 agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta cgcaattgtt
     7561 tgaaaaaggc ttgggattag tttgacacgg tatcagattt tactgttttt gctggagcat
     7621 tctccttgta accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc tgctttgaca
     7681 cggcatttca agattttgga aacggaaggt ttggtggagc gtcatcgtaa tcctgaaaat
     7741 cagcgggaag tgttggtaga ggctgcgaag tatgccaagg agcagttagt ggtgaatccc
     7801 cctctgcaac atatcaaggt taaggaagag atggaaagta tcttaacaga gtttgagaga
     7861 acagaactca gccgtttatt aaataaattg gttttgggta ttgaaaatat agaaatttaa
     7921 ggagaaatag atgtcaatta ttttaacaac gatcgttgct ttggagcatt tttacatttt
     7981 ttatttggaa agtattgcca cgcaatcaga tgcgactagt cgtgtattta atatggaaaa
     8041 ggaagaattg gctcatccgt cagtaagttc attgttcaaa aatcaaggaa tttataaggc
     8101 tctgctagga gtctttctct tgtatgtcat ttatttctca cagaatttag aaattgtgac
     8161 tatttttgtc ttatttgtga ttggtgctgc gacttacggc tctttaacag cggataaaaa
     8221 attattttga agcaaggtgg atcagctatt ttggccttga ttagtatttt actctttaaa
     8281 tacacttgaa ggttgattct aatctcgcta atccttttta atccagaata agggaaatat
     8341 gttatacttg tttttaagaa aaaagtctca ttgaattggt tttgaggagt tagaaatgaa
     8401 agtattagtg acaggttttg agcccttttg aggccattaa aggtttacca gctgaaatcc
     8461 atggtgctga ggtccgttag ctagaggtgc cgacagtttt tcacaaatct gctcaagtat
     8521 tggaagaaga gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg
     8581 gaagaactag tttgacacct gaacgagtgg ccattaatca agacgatgca cgcatttctg
     8641 ataacgaaga taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact
     8701 ttagtagttt gccgattaaa gcgatggttc aagctataaa aaagagggct taccggcctc
     8761 tgtttccaat acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt
     8821 ggtagaaaag aaatttccat atgttaaggc aggttttatg catattcctt atatgatgga
     8881 acaggtggtg aacagacaga ctattccagc tatgagttta gtggatattc ggagagggat
     8941 agaagcagca atcggcgcta tgatagaaca tggagatcag gaactcaagt tggtaggcgg
     9001 agaaactcat tgatagaaaa aagcttgagt ggaaaaacct tcaagctttt ggacgttttc
     9061 gagccaatac tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa
     9121 aactagcaat gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta
     9181 ggacaaagcg ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc
     9241 ttggtgggac ctgtcctagg tctagactat aacagagaag aaattccacc tgtgaatagg
     9301 cataatactg tggaatatag aggatatttc ctacaatgat caagatgaga cttgcaagaa
     9361 agtagagtcc aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg
     9421 gaaactcagg atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt
     9481 aaatcccaag taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg
     9541 tcaaaaaggt ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg
     9601 gctccgtttt agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa
     9661 tagtcccgat aaagaagact agtagaggaa agaggtaggc ttgaagtatt tggccaagta
     9721 tgctgaaaaa tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac
     9781 tagataagat gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag
     9841 cctgaaaatg ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc
     9901 tcttattata ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa
     9961 tcatacagtg tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag
    10021 gtaaaaaatg tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg
    10081 agctcgtctg ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc
    10141 agttgggaca caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc
    10201 gggaattatc ctatcaaaca cctatcatct ctggcttcgc cctggagatg aactcattgc
    10261 acgcgctggt ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg
    10321 tggttttcag gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt
    10381 taaaaatcat ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca
    10441 gaataatctg ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc
    10501 ttatgactac gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa
    10561 ggctcaccgt cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga
    10621 agaccttcgc cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat
    10681 cggtggtttg gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac
    10741 tcaactgcta cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt
    10801 gatcgatggg gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc
    10861 tcgtaacggg acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc
    10921 tgaggacttt acgccactgg atcctgagtg tgactgctac acatgtaata actatacacg
    10981 cgcttacctt cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta
    11041 ccacaatctt tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga
    11101 caatctcttg gaattccgtg agtattttgt ggaaaaatat ggctataata agtcaggacg
    11161 taatttctaa aatggaattg atataaaaaa atcctaagtt ttctcttagg atttttcttc
    11221 tttttttgat agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat
    11281 ggttttcctt gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga
    11341 cgatctttcc tggaggattc ttcggggtag atgtcttttt cacattttca ggtttcctga
    11401 ttacagctct actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt
    11461 ttagaagacg cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc
    11521 cttttacttt cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg
    11581 tcttaggctt tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt
    11641 tcattcctca tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc
    11701 tttggggatt ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg
    11761 ggatggtctt tctcttatct gctgctgcct tcttgatcag tttcttctcc atgtttattg
    11821 gtagttttct agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc
    11881 cattcttttt gggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg
    11941 tcaagcagtt ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct
    12001 ttggtttcct agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta
    12061 tcggcttctt gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac
    12121 atgaaaagac acatcatata caggagccga agattatcag ctttttagcg gatactagct
    12181 atgcggttta tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc
    12241 ttcttgctgt attactgact ctgatttgtt cttatggctt tgccagtctg tcattctatg
    12301 tattggaacc ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc
    12361 cttatattca cgcaattctt gcagcaggta caggaatctt gaccttcatt gtctgcatgg
    12421 tgaccttgtt ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga
    12481 agcaagctgc aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca
    12541 gtttgggaat tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata
    12601 cagcactaca gacagttctt cctggagcac agattaacgc gcaggtcagc gtaacaacca
    12661 agaccgcaaa tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg
    12721 tcattgcgac tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga
    12781 aaaatcttcc taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa
    12841 aagagaccta tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga
    12901 caccttacat tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg
    12961 caggaacaga ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat
    13021 tgtatgcaga tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa
    13081 aataacttgt attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca
    13141 aaaaataggt ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa
    13201 taaattgtag aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga
    13261 tcagtttttc tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa
    13321 gtttgggaaa catgtagagc agattcctga aggggctgag gtgattgact atacaggtta
    13381 tagcattgcc ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat
    13441 ggacaacaac attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt
    13501 taccagtttc ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga
    13561 aaatcttgga aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga
    13621 aggtccatat ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc
    13681 gggtgttgag gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc
    13741 ccttgcacca gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt
    13801 gacggttgct cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc
    13861 tggagcgagt gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt
    13921 gggtatggtt ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg
    13981 tcaccacgta gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat
    14041 cgctcttatc acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg
    14101 agaattccca gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc
    14161 aggttctatc ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa
    14221 tccgcatgaa gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga
    14281 cgtctgtggc caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt
    14341 ggaattggta gcaacctacc tagatggcgt gaaacgttat caagcataag agagaaagca
    14401 gaagttagag actaacttct gcttttttat gcagggtact ttactggtaa ataaaaagtt
    14461 aaaaaaatca caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa
    14521 tattacaaat aaaaaaacgg aggagtgctt tatgaaagct tatacttatg ttaaaccagg
    14581 acttgcttct tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt
    14641 gcgtattgta aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc
    14701 tacttgccaa agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg
    14761 ggaaggagtt tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg
    14821 tggtaaatgc tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg
    14881 gattttcggt cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga
    14941 taatactctt taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga
    15001 cattctgcct actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag
    15061 cgtagccatt attggttcag gtccagttgg attggctgct cttttaacag cccaattcta
    15121 ttcaccagct aaattgatta tggtagacct agacgataac cgtttggaaa ctgccctatc
    15181 attcggtgcg actcataagg taaactcttc agaccctgaa aaagcgataa aagaaattta
    15241 tgatttgaca gatggtcgcg gtgtagatgt cgctattgaa gctgtaggga ttcctgaaac
    15301 atttgatttc tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca
    15361 tggtaaacca gttgaattcg atttagataa actttggatt cgtaacatca atgtaacaac
    15421 tggtttggta tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat
    15481 tgaaccggaa aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga
    15541 agtcttcagt aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc
    15601 agaagcctaa gtagtaaaaa tatttttgta cataagcaaa tagaaattca gtcatccatc
    15661 agatggctgg attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc
    15721 ggaattggtt ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat
    15781 gtacggagat tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag
    15841 tagaaaattt gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt
    15901 agaacaagaa tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc
    15961 ggaagaccaa cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc
    16021 tcttttgcag gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca
    16081 aaccagtcag gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt
    16141 tttggagttg ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag
    16201 tatggttcaa gaaattgcac aagaaatcat tcgttcggct cggaaaaaag gggcgcaaga
    16261 catttatttt gtccctaagt tagatgccta tgagcttcat atgagggtag gagacgagcg
    16321 ctgtaaaatt ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt
    16381 tgtggcgggt atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc
    16441 ctatgaccag aagatggcgt ctctacgttt atctactgta ggcgattatc gggggcatga
    16501 gagtttggtt atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga
    16561 tattgaagaa ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt
    16621 tgggagtggt aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca
    16681 agttatgtcc atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt
    16741 gaacgaagca atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc
    16801 agatctcttg attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc
    16861 tagtttgaca ggtgcgacag tcttttcaac cattcacgcc aaaagtatcc gaggtgttta
    16921 tgagcgtctg ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt
    16981 ctgctaccag agattaatcg ggggaggagg aatcgttgac tttgcaagca gagattatca
    17041 agaacaccaa gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat
    17101 cacaagtctt caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca
    17161 ccctatttaa caatctcttt tctagcggtt ttcatctggt ggagaccatc tcctttttag
    17221 ataggagtgc tttgttggac aagcagtgtg tgacccagat gcgtgtgggc ttgtctcagg
    17281 ggaaatcatt ctcagaaatg atggaaagtt tgggatgttc aagtaccatt gtcactcagt
    17341 tatctctagc tgaagttcat ggcaatcttc acctgagttt gggaaagata gaagaatatc
    17401 tagacaatct ggccaaggtc aagaaaaagt taattgaagt agcgacctat cctttgattt
    17461 tgctgggttt tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg
    17521 atagtagcaa tattgccacc cgaattatcg gtaatctgcc acaaattttt ctaggcatgg
    17581 tagggcttgt ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga
    17641 tgagtgtctt ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact
    17701 tgacagccta ttatgcacgt gaatggggga atatgatttc acagggaatg gagctgacgc
    17761 agatttttca aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc
    17821 tggctcaaac cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct
    17881 ttaggaagga attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg
    17941 agttggaaat ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca
    18001 tgaatttggt gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg
    18061 cggcaatgct catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg
    18121 atgacattct tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttggtggtc
    18181 ttgctgatta tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa
    18241 gcagtcaatg acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt
    18301 tatagcttgg aaaagaatga agatgctagc ctaagcaagt taaaagacga tgggcgaatc
    18361 acggaagaac aggttaaagc ttataaagaa tacaatgata aaaatggagg agcaaatcgt
    18421 aaagtcaatg attaaggcct ttaccatgct ggaaagtctc ttggttttgg gtcttgtgag
    18481 tatccttgcc ttgggcttgt ccggctctgt tcagtccact tttgcggcag tagaggaaca
    18541 gattttcttt atggaatttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag
    18601 tcagcaaaag actagtctga acttagatgg gcagatgatt agcaatggca gtcaaaagtt
    18661 gccagtccct aaaggaattc aggccccatc aggccaaagt attatatttg accgtgctgg
    18721 gggcaattcg tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca
    18781 attatatcta ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga
    18841 ttttactgga agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg
    18901 gacaaattca aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga
    18961 gggtagctaa gatggccttg cagacggggc aaaatcagat aaacatcaac ggagttgaga
    19021 ttcaggtatt ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg
    19081 caatcaaaga gccataaggt caaggctttt accttgttag aatccctgct tgccctgctt
    19141 gtcatcagtg ggggcttact cctttttcaa gctatgagtc agctcctcat ttcagaagtt
    19201 cgctaccagc aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggca
    19261 gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat
    19321 ggcaaggaca tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt
    19381 ggacgaggtt atcagcctat ggtttatggg ctcaaatccg cacagattac agaggacaat
    19441 caactggtgc gctttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt
    19501 gtggaaaaag aaaaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat
    19561 ctttagtctt ttgttgcaat tttatttgaa ccgacaaatc gcccactatc aagactatgc
    19621 tttaaataaa gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga
    19681 gcaagaaagt ggggaacagg tctttaatct aggtcaggta agctatcaaa acaagaaaac
    19741 aagcttggtg acgactgttc gtacgtctaa gagccaatat gagtttctgt ttccttcagt
    19801 caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa
    19861 agtggagaag aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca
    19921 actataatgc gttgaatcca gaatagttca ctgtagtttc tagaaaattg ctggaaatgg
    19981 atgttaagct ccaatttatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa
    20041 ctaaagatat gaaacatgat tttaaccaca aagcagaaac tttcgattcc cctaaaaata
    20101 tcttcctcgc aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca
    20161 aagaaatttt agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg
    20221 ctaagtcagt tactcttgta gacatttctg agaaaatgtt ggagcaagct catttgaaag
    20281 cggagcagca agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct
    20341 tggagaaaga gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg
    20401 atgcggctct ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg
    20461 attttaccaa gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc
    20521 taattgagca tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacttgt
    20581 ttcaaggaaa tcactcagaa ttctttttaa tagtagccca aaaatcactc gcctagtcag
    20641 ggagtgattt ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg
    20701 attttgaaaa aattgaacaa gcttatacct atttactaga gaatgtccaa gtcatccaaa
    20761 gtgatttggc gaccaacttt tatgacgcct tggtggagca aaacagcatc tatctggatg
    20821 gtgaaactga gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac
    20881 gcaaagaaga atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac
    20941 ccttgcaggc caatcaccag tttacaccgg atgctattgc tttgcttttg gtgtttattg
    21001 tggaagagtt gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa
    21061 ttctaggcgc tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaag
    21121 tggatgattt actgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg
    21181 gctttgtcca aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca
    21241 gtgacttgcc tgtcggctat tatcctgatg atgccgttgc gtcgcgtcat caagttgctt
    21301 ctagccaaga acatacttac gcccatcact tgctcatgga acaaggattt aagtacctta
    21361 agtcagatgg atatgctatt tttctagctc cgagtgattt gttgaccagt cctcaaagtg
    21421 atttgttgaa agtctggttg aaagaggagg caagtctggt tgctatgatt agtctgcctg
    21481 aaaatctctt tgctaatgct aaacaatcta agactatttt tatcctacag aagaaaagtg
    21541 aaatagcagt ggagcttttt gtttatccac ttgctagctt gcaagatgca agtgttttaa
    21601 tgaaatttaa agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt
    21661 gttataatag ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa caattgcaat
    21721 caatgcagga agttcaagct taaaatggca attatactta atgccagagg aaaaagtatt
    21781 ggcgaaaggc ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga
    21841 cggccgttct gaacaacaaa ttttggatat cgaaaatcat acacaagccg ttaaaatttt
    21901 attggatgac ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg
    21961 ccaccgtgtt gtagcaggtg gagaatattt caaagaatca acagttgttg agggagatgt
    22021 tttagaaaaa gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc
    22081 aggtgttcgt gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac
    22141 ttccttccac acaagtatgc cagagaaagc ttatcgctac cctctaccaa caaaatatta
    22201 cacagaaaac aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg
    22261 agaagctgca aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat
    22321 tggtaacgga ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg
    22381 gttcactcct cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat
    22441 cattccttat ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt
    22501 tcttaaccgt gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat
    22561 agaagcagct gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga
    22621 ccgtatccaa aaacatatcg gtcagtacct tgcagtgcta aatggaacag atgccattgt
    22681 tttcacagca ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat
    22741 ttcgtggttt ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat
    22801 ctcaacagag gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat
    22861 tgcccgtgac gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg
    22921 agttgggaaa gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat
    22981 gattggcttt tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt
    23041 tgaagaaaaa ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga
    23101 caagttttgc taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc
    23161 gagtaggtct atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc
    23221 gacggattcg gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg
    23281 ttgtcattgc tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac
    23341 tccatgtatt aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta
    23401 aagttgacta gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg
    23461 gtaactagcg atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt
    23521 gcggaaatca ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt
    23581 acggtcttga ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg
    23641 aaaatgcagg aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat
    23701 atggaaagca gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc
    23761 agacagtcag actctctttg gccgattttg attcagatgc cggttatttt ggccctgttc
    23821 caagccctat caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt
    23881 agtgtggata caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact
    23941 tggttgtcca acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg
    24001 attccagtct tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg
    24061 acagtgtcta atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt
    24121 atcgcagagc gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa
    24181 gccaagaaaa aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt
    24241 acaggttcaa ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga
    24301 atgaaggctc atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt
    24361 aaaaaaccag cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat
    24421 caacaggtag taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg
    24481 gttagtgaag aaaccgttga ccttggtcat gtagttgatg ctattaaaaa aatagaggaa
    24541 gaaggtcaag gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc
    24601 agcactatct tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa
    24661 gcgatgaggg aagaagcagg cgctgatgac cttgaaactg agcaagacca agctgaaagt
    24721 caagaactag aagacttggg cttgaaagtt gaaacgaact ttgatattga acaagtagct
    24781 acggaagtaa tggcttatgt tcaaacgatt attgatgaca tggatgttga ggctacactt
    24841 tcaaatgatt ataaccgtcg tagcatcaat ttgcaaattg atactaacga accaggtcgt
    24901 attatcggct accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt
    24961 tacaactgct attcaagaac cttctatatc actattaatg tcaatgatta tgttgaacac
    25021 cgtgcagaag tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga
    25081 cgcagtcatc aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt
    25141 tcacgtatgg atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt
    25201 gtagatacag aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta
    25261 aactgatgtt gaataagata agagactatc tagacttttc tggtttgcag taccgtagtc
    25321 ctgataaagc gggagcagag cgagagaaga tgctggcatt ccgtcacaaa ggacaagagg
    25381 cccgaaaggc ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac
    25441 tccaacagac tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt
    25501 atctacagag agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat
    25561 ctactgactt tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa
    25621 ctttagagaa acaggccaag attttagaca ttccaaccgt taaaggaatt tattatctag
    25681 cctactctga tggccaaagt caacggtggg aggcgaacga agaaaagcgt cgtactttac
    25741 gcgagaaggt gagaagtcaa gaagttcgaa aagttttagt gaaggtagat gttcctatga
    25801 cagaaaattc gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc
    25861 ttccctatta tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag
    25921 tccaagagtg aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat
    25981 ataataaact tacaaaaaca attcaaaagg agaacaatta tggaagtcat ttcaagtgtt
    26041 ctaaattggt tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg
    26101 ttgataggat atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa
    26161 gcaacagtag ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt
    26221 ccaatcttag cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac
    26281 tttggacttg ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact
    26341 gcaactacag ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag
    26401 attacgaagg taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca
    26461 gtatctctta tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg
    26521 attggtatca tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact
    26581 caacgcttga ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg
    26641 tttgtagata aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa
    26701 ttacctaagt tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc
    26761 gtattcttcg gagccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc
    26821 atcacttcag gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa
    26881 acagccttta ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta
    26941 tctgagttga caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca
    27001 gcggttgacg ttgcagcttc ttatggattt ggttctccaa atgctgtcct gtcaggattt
    27061 atctttggtt tgattggtca attgattaca attgttttgc tcatcgtctt taaaaatccg
    27121 attcttatta ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac
    27181 gctgataaac gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt
    27241 caagttgctc taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac
    27301 catggaaata tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt
    27361 ggtattgttg gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt
    27421 gccaaagcaa aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat
    27481 ctagaaaagg agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc
    27541 atcaatggtt atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt
    27601 tacagtcaat tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt
    27661 aatcgcttct cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg
    27721 gcttgataac ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta
    27781 aaaggttgga gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt
    27841 aaataaagga ggcagatatg aatttaaaac aagctttaat tgacaacgac tcgatccgac
    27901 taggtttaga ggctaacgat tggaaagaag cagtcaaggt agcagtagat cccttgattg
    27961 aaagtggggc aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg
    28021 ggccttacta tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg
    28081 tgcaaagtga tgccttttca ttaattacct tacaaaatcc tgttgtattt tcagatggga
    28141 aagaggtatc tgttttgttg gcactagcag caacaagttc aaaaattcac acaagtgtag
    28201 ccattccaca aattattgcc ctgtttgaat tagaagattc tattgcacgt ttacaggctt
    28261 gccagactaa agaagatgtc ttggctatga ttgaagaatc taaggatagc ccttatctcg
    28321 aaggattgga tttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat
    28381 ttacaagttg cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt
    28441 ggtcaggaag tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa
    28501 ctggctgaag tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt
    28561 gctgatgctg gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact
    28621 tgtatctgtt gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa
    28681 cgaggagaac gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct
    28741 cagctttggc tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt
    28801 cttgctggtg aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg
    28861 ggcttccgtg tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt
    28921 gttgatgtct ttacctttat cgcaggtcgt ggaattacag aggctgtgga tccagcagga
    28981 gcagcgcgtg ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca
    29041 attggaattt atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt
    29101 gccaaggagt taggctttga ttttatcgag atgtctattg acgaacgtga cgagcgttta
    29161 gcaagacttg actggagtaa ggaagaacgc ttggaagttg tcaaagaaat ctatgaaact
    29221 ggtgttcgta ttccttctat ctgtttttca ggccatcgtc gctacccatt gggatcaaaa
    29281 gattcagttc tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa
    29341 gacttgggag ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca
    29401 ccccagacac gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa
    29461 gctcaggtgg tacttgctat tgaaattatg gatgatcctt tcatcagtag catcgaaaaa
    29521 tatttggcta tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt
    29581 aatgtgtctg catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc
    29641 gcagctctcc atctcaagga tacttatgca gtgacagaaa gttcaaaggg ccagttccga
    29701 gatgtacctt tcgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa
    29761 accaattata atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa
    29821 gaaacacgcg cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca
    29881 ggtttgatgt aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgatgccaa
    29941 tcaatcattg ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagttaa
    30001 tcgcgaactc ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc
    30061 tgaaaacatg gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc
    30121 ttccgacctc ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt
    30181 tcacacccat tcgacagaag ctgttggttg ggctcaggca ggtcgtgata ttcctttcta
    30241 cggaacaacc catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa
    30301 ggacgaagta gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga
    30361 acatcgcgga cttaacccgg ttgaagtacc aggaattatt gtacgcaatc acggtccatt
    30421 cacctggggc aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc
    30481 aaagatgaat cgctttacag aacaaatcaa tccaagagtt ggacctgctc cccagtacat
    30541 actagaaaaa cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga
    30601 acgatgaagg aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga
    30661 gagtaaagtt ggaattgaag taattttaaa agatttttta gaaatagcgc ttgatatata
    30721 tatggtaaaa taaaaagaat tgctgtgata tcaatagatt tgggggattt tttaatatgg
    30781 tactggataa ggcaagttgt gatttgcttc aatatttgat ggatcaagaa acgtccaaaa
    30841 cgattatggc gatttcgaaa gatttgaaag agtcaagaag gaaaatttat tatcacattg
    30901 acaaaatcaa tgctgctctg ggtgacgagg cgcttcacat cattagtatt ccacgaattg
    30961 gtattcactt aacggaagag cagagagatg cttgttgtaa actattatcg gaagtagatt
    31021 cgtacgatta tatcatgagt gcgcatgaac gtatgatgat aatgttacta tggataggta
    31081 tttctaaaga acgtattacg attgaaaaat tgatagagtt aacagaggta tctaggaata
    31141 ctgttctcaa tgatttgaat agtattcgtt atcaactaac tttggaacaa tatcaggtga
    31201 tcttgcaagt gagcaagtca cagggatacc accttcatgc ccaccctctt aataaaattc
    31261 agtatcttca atcgcttcta tatcatattt ttatggaaga aaatgccact tttgtatcta
    31321 ttttagaaga taagatgaaa gagaggttag atgatgagtg tttgctttct gttgaaatga
    31381 accaattttt taaggaacag gttcctttag ttgaacaaga tttagggaag aaaataaacc
    31441 atcatgaaat aacttttatg ttgcaggttc taccttattt gctgttaagc tgtcataatg
    31501 ttgaacagta tcaagaaaga catcaggata tagagaaaga attttctttg ataagaaaaa
    31561 gaatagagta tcaggtgtct aagaaattag gagaacggtt gtttcaaaag tttgaaattt
    31621 ctttgtcagg acttgaagtt tctcttgtag ctgttctcct cctctcctat cgtaaagatt
    31681 tggatattca tgcagaaagt gatgattttc ggcaattaaa acttgcttta gaagaattta
    31741 tctggtattt tgaatcacaa atccgaatgg agattgagaa caaggatgat ttgttacgaa
    31801 atttgatgat ccactgtaaa gccttgttat ttagaaagac ttacggtatt ttttctaaaa
    31861 atcctctaac aaaacaaatt cgatccaagt atggagaatt atttttagtc actagaaaat
    31921 ctgcggaaat tttagaagga gcatggttta ttcggctaac agacgatgat attgcctatt
    31981 tgacgattca tattggagga tttttaaaat atacaccatc gtctcaaaaa aatatgaaaa
    32041 aagtttatct cgtttgtgat gaaggtgttg cggtttcgag acttttgctg aaacaatgca
    32101 aactttattt tccaaatgag caaattgaca ctgtatttac aacagaacaa tttaagagtg
    32161 tggaagatat tgcacaagtt gatgtagtga ttactactaa tgatgatttg gatagcagat
    32221 ttccgatttt aagggttaat cctatccttg aagcagaaga tattttgaaa atgctagact
    32281 atcttaaaca caatatattt cgtaataaga gcaaaagttt cagtgaaaat ctttctagtc
    32341 ttatttcgtc ttatattgta gacagcaagt tggctagtaa gttccaagaa gaggttcaaa
    32401 cacttataaa tcaagaaata gtagttcaag cttttttgga agatatttga aggacagtcc
    32461 aatgatgaac acaaacctgt gtttttcttg gtctttttta gtgttttgaa gggtggtata
    32521 ctaatctcaa agataacaat tatatccaaa ggaggcaaca tatgccaaac gtcaaagaaa
    32581 ttacaagaga gtcatggatt ttagccactt tcccagagtg gggaacatgg ttgaacgaag
    32641 aaatcgaaga agaagtcgta cctgaaggca actttgccat gtggtggcta ggcaactgtg
    32701 gtacttggat taagacacca gctggtgcta acgttgtcat ggacctttgg tcaaaccgtg
    32761 gaaaatcaac caaaaaagtg aaagatatgg ttcgtgggca ccaaatggca aatatggcag
    32821 gtgttcgtaa gttgcaacca aacttgcgtg ttcagccaat ggttatcgat ccatttgcta
    32881 tcaacgaact agactattac ttagtttcac acttccacag tgatcatatc gacccataca
    32941 cagctgcagc aattctcaac aatcctaagt tagagcatgt taagtttatc ggtccttacc
    33001 actgtggacg aatctgggaa ggatggggtg ttccaaaaga acgtatcatc gttgttaaac
    33061 caggtgacac tatcgaatta aaagatatga agattcatgc agtagaatca tttgaccgta
    33121 cttgcttggt aactctccca gtgaacggtg ctgatgagac aggcggtgaa cttgctggct
    33181 tggctgttac agatgaagaa atggctcaaa aggctgttaa ctatatcttt gaaacaccag
    33241 gtggaaccat ctatcatggt gcagattctc acttctcaaa ctattttgca aaacatggta
    33301 aagactttaa aattgatgtt gctttgaata actatggtga aaatccggta ggtatccaag
    33361 acaaaatgac atctatcgac cttcttcgta tggcagaaaa tctgcgtacc aaagtcatta
    33421 tcccagttca ctatgatatc tggtctaact tcatggcttc tactaatgag attctagaac
    33481 tttggaaaat gcgaaaagat cgcttgcaat acgatttcca tccatttatc tgggaagttg
    33541 gcggtaagta cacttatcct caagatcaac acttagtaga ataccatcat ccacgtggtt
    33601 ttgatgattg ttttgaacaa gactctaaca ttcaatttaa agctttgcta taatataaaa
    33661 atattctttg gaggttatcc gtatgttgca tgatacggat aattttcata taatagtaaa
    33721 atagaatgtg tgattcaata atcacctcaa atagaaagga aattctatgt caaatctatc
    33781 tgttaatgca attcgttttc taggtattga cgccattaat aaagccaact caggtcatcc
    33841 aggtgtggtt atgggagcgg ctccgatggc ttacagcctc tttacaaaac aacttcatat
    33901 caatccagct caaccaaact ggattaaccg cgaccgcttt attctttcag caggtcatgg
    33961 ttcaatgctc ctttatgctc ttcttcacct ttctggtttt gaagatgtca gcatggatga
    34021 gattaagagt ttccgtcaat ggggttcaaa aacaccaggt cacccagaat ttggtcatac
    34081 ggcagggatt gatgctacga caggtcctct agggcaaggt atttcaactg ctactggttt
    34141 tgcccaagca gaacgtttct tggcagccaa atataaccgt gaaggctaca atatctttga
    34201 ccactatact tacgttatct gtggagacgg agacttgatg gaaggtgtct caagcgaggc
    34261 agcttcatac gcaggtttgc aaaaacttga taagttggtt gttctttatg attcaaatga
    34321 tatcaacttg gatggtgaga caaaggattc ctttacagaa agtgttcgtg accgttacaa
    34381 tgcctacggt tggcatactg ccttggttga aaatggaaca gacttggaag ccatccatgc
    34441 tgctatcgaa acagcaaaag cttcaggcaa gccatctttg attgaagtga agacggttat
    34501 tggatacggt tctccaaaca aacaaggaac taatgctgta cacggcgccc ctcttggagc
    34561 agatgaaact gcatcaactc gtcaagccct cggttgggac tacgaaccat ttgaaattcc
    34621 agaacaagta tatgctgatt tcaaagaaca tgttgcagac cgtggcgcat cagcttatca
    34681 agcttggact aaattagttg cagattataa agaagctcat ccagaactgg ctgcagaagt
    34741 agaagccatc atcgacggac gtgatccagt cgaagtgact ccagcagact tcccagcttt
    34801 agaaaatggt ttttctcaag caactcgtaa ttcaagtcaa gatgccttga atgttgtggc
    34861 agctaaatta ccaacctttc taggtggatc agctgacctt gctcactcaa acatgactta
    34921 tatcaagacg gatggacttc aagacgatgc caatcgcttg aatcgtaaca ttcagtttgg
    34981 tgttcgtgaa tttgcaatgg gaacaatctt gaacgggatg gcccttcatg gtggacttcg
    35041 tgtatacggt ggaactttct tcgtcttctc tgactatgtg aaggcagctg tccgcttgtc
    35101 agccttacaa ggacttcctg tgacttatgt ctttacccat gattcaatcg cagttgggga
    35161 agatggtccg actcacgaac cagttgagca tttagcaggt cttcgtgcta tgccaaatct
    35221 aaatgttttc cgtccagcag atgcgcgtga aacgcaagca gcttggtacc ttgcagtgac
    35281 aagtgagaaa acaccaactg cccttgtctt gacacgtcaa aacttgactg ttgaagatgg
    35341 aacagacttc gacaaggttg ctaaaggtgc ttatgttgta tatgaaaatg cagccgactt
    35401 tgataccatc ttgattgcga caggttcaga ggttaatctt gctgtctcag ctgctaaaga
    35461 attggctagt caaggcgaaa aaatccgcgt agtcagcatg ccatctacag atgtctttga
    35521 taaacaagat gcagcttaca aggaagaaat tcttccaaat gcagtccgcc gtcgtgttgc
    35581 agtcgaaatg ggtgcaagtc aaaactggta caaatatgtt ggtctcgatg gtgccgttct
    35641 aggtattgat accttcggag cctctgcccc agcaccaaaa gtattggcag aatatggctt
    35701 tactgtagaa aatcttgtaa aaattgttcg aaacttgaaa taatcctaaa aatcagggcg
    35761 taagctctgg tttttcttac cagaaaagta aggtacaatc ttgtaaaagt agctgaaatt
    35821 tgatatagta gtcctatgta aaagacaaag gagaaaacaa tgaatccaaa tattactttt
    35881 ttaatcatgc ttgtaggtat gatggccttg atgttcttta tgcaacgttc tcaaaagaaa
    35941 caagctcaaa agcgtatgga aagcttaaat aaactacaaa aaggctatga agtgattaca
    36001 atcggtggac tttatggaac agtcgatgaa gtagatacgg agaagggaac aatagttctt
    36061 gacgtagatg gagtttactt gacttttgaa ctagctgcta tcaagacagt attaccgctg
    36121 aaagaaacag cttcactaga aggcgcaatt gaaaaataag acgggatcac gaactcccgt
    36181 ttttctataa aagaaaggaa atgggatgaa aaaattagtc tttgtctgtc tgggaaatat
    36241 ttgccgtagc cctatggccg agtttgttat gaaatcaatg acagataact acgaaatcca
    36301 aagtcgagca acttcctctt gggaacatgg caatccgatt cataagggga ctcagggaat
    36361 ttttcaacag tatgagattc tttatgacaa gaacaagaca tcgcttcaga ttagtaagga
    36421 agattttgaa gcctttgatt atattatcgg aatggacgct tcaaatattt ctgacttacg
    36481 tcagatgtgt ccagtagact gtcaagataa gatttactca ttttcatctg aaagtgttcc
    36541 agacccttgg tatacaggag attttgaaga aacctatcga cgtgttcaag agggctgtca
    36601 agcttggtta gaacgtttag aaaaggagag ttaaggtgga aaatcttacg aatttttacg
    36661 aaaagtatcg tgtctatctg actcgtccac gtttagagct tttggcagta gttaccattg
    36721 ttttctgtgc tgtactcgtc ttttttctaa atattccagg aaaaggtgtc ttaaaactcg
    36781 ataatggaac gattgtttat gatggcagtc ttgtccgtgg taaaatgaat ggtcaaggta
    36841 ccattacctt ccaaaatgga gaccaatata caggtggctt caacaatgga gccttcaacg
    36901 gaaaaggtac ctttcaatct aaagaaggct ggacctacga aggtgatttt gtaaatggtc
    36961 aggctgaagg aaaagggaaa ctaacaacag aacaagaagt cgtttatgaa ggaactttta
    37021 aacaaggcgt ttttcaacaa aaataaagcc tccttatcca aaggaggtat tattagaacc
    37081 acaaggtaag cgcttacctg taaatccctt tctttccaaa tccctcttcc aagcaagttt
    37141 gtgaaataaa aaatatttga aataaatttc acaaacttca aagataaaac ctgataagaa
    37201 aagaaaatga gaaaagtttc acaagagttt aaaaattctt tgtgaaatgt ttatgaaact
    37261 gtttacaaag ttgaaataat gcgttataat aaacttgtga aaaaattaac aaaggatatc
    37321 gttccttgaa agctatggag gaaaatatgg ctgataaaaa aactgtgaca ccagaggaaa
    37381 agaaactcgt tgctgaaaaa cacgtagatg agttggttca aaaagctcta gttgcccttg
    37441 aagaaatgcg taaattggat caagagcaag ttgactacat cgttgctaaa gcatcagtag
    37501 cagctttgga tgcccacgga gaattggctt tacatgcctt tgaagaaaca ggacgtggtg
    37561 tatttgaaga taaagcaact aagaacttgt ttgcctgtga acacgtagta aacaacatgc
    37621 gtcacactaa gacagttggc gttatcgaag aagacgatgt aacaggattg actcttattg
    37681 ctgaaccagt tggtgttgtt tgtggtatta ctccaacaac aaacccaaca tcaacagcaa
    37741 tcttcaaatc attgatttca ttgaagacac gtaacccaat cgtctttgcc ttccatccat
    37801 cagcacaaga atcatctgct catgcagctc gtatcgtccg cgatgcagct atcgcagctg
    37861 gtgctcctga aaactgtgtg caatggatta ctcaaccatc tatggaagca acaagtgccc
    37921 ttatgaacca cgaaggtgtt gcgacaatcc ttgcaacagg tggtaatgcc atggttaagg
    37981 cggcttattc atgtggtaaa ccagctcttg gggtaggtgc cggaaacgtt ccagcttatg
    38041 ttgaaaaatc agcaaacatt cgtcaagcag cacacgatat cgtcatgtct aaatcatttg
    38101 ataacggtat ggtctgtgca tctgaacaag cagttatcat tgataaagaa atttacgatg
    38161 aatttgtagc agagttcaaa tcttaccaca cttactttgt aaacaaaaaa gaaaaagctc
    38221 ttcttgaaga gttctgcttc ggcgtcaaag caaacagcaa aaactgtgct ggtgcaaaat
    38281 tgaacgctga catcgttggt aaaccagcaa cttggattgc agaacaagca ggatttacag
    38341 ttccagaagg aacaaacatt cttgctgcag aatgtaaaga agttggcgaa aatgagccat
    38401 tgactcgtga aaaattgtca ccagttattg cagttttgaa atctgaaagc cgtgaagatg
    38461 gtattactaa ggctcgtcaa atggttgaat ttaacggtct tggacactca gcagctatcc
    38521 acacagctga cgaagaattg actaaagaat ttggtaaagc tgttaaagct attcgtgtta
    38581 tctgtaactc accttctact tttggtggta ttggggacgt ttacaatgcc ttcttgccat
    38641 cattgacact tggatgtggt tcttacggac gcaactcagt tggggataac gttagtgcca
    38701 ttaacctctt gaatatcaaa aaagtcggaa gacggagaaa taacatgcaa tggatgaaac
    38761 ttccttcaaa aacatacttt gaacgtgatt caattcaata ccttcaaaaa tgtcgtgacg
    38821 ttgaacgtgt catgatcgtt actgaccatg ccatggtaga gcttggtttc cttgatcgta
    38881 tcatcgaaca actggacctt cgtcgcaata aggttgttta ccaaatcttt gcggatgtag
    38941 aaccggatcc agatatcaca actgtaaacc gtggtactga gattatgcgt gccttcaaac
    39001 cagataccat catcgcactc ggtggtgggt ctccaatgga tgctgccaaa gtaatgtggc
    39061 tcttctacga gcaaccagaa gtggacttcc gtgaccttgt ccaaaaattc atggatatcc
    39121 gtaaacgtgc cttcaagttc ccattgcttg gtaagaagac taaattcatc gcgattccaa
    39181 ctacatctgg tacaggatct gaagtaacac catttgccgt tatctctgat aaagcaaaca
    39241 accgtaaata cccaatcgct gactactcat tgacaccaac tgtggcaatc gtagatcctg
    39301 ctttggtatt gacagttcca ggatttgttg ctgctgatac tggtatggac gtattgactc
    39361 acgcgacaga agcatacgta tcacaaatgg ctagtgacta cactgatggt ttagcacttc
    39421 aagccattaa attggtcttt gaaaatctcg aaagctcagt taagaatgca gacttccact
    39481 cacgtgagaa aatgcataac gcttcaacaa tcgctggtat ggcctttgcc aatgccttcc
    39541 taggtatttc tcactcaatg gcccataaga ttggtgcgca attccacaca atccacggtc
    39601 gtacaaatgc catcttgctt ccatacgtta tccgttacaa cggtacacgt ccagctaaga
    39661 cagcaacatg gcctaagtac aactactacc gtgcagatga aaaataccaa gatatcgcac
    39721 gcatgcttgg acttccagct tctactccag aagaaggggt tgaatcttac gcaaaagctg
    39781 tctacgaact cggtgaacgt attgggatcc aaatgaattt tagagaccaa ggaattgacg
    39841 aaaaagaatg gaaagaacat tctcgtgaat tagccttcct ggcttatgaa gaccaatgtt
    39901 caccagctaa cccacgtctt ccaatggtag accatatgca agaaatcatc gaagatgcat
    39961 actatggcta caaagaaaga ccaggacgcc gtaaataatt gtttatcagt ctagaagcaa
    40021 gacaaaaact caatttgagg gaaagatcca gtaatttttc tatgataaaa ggcatcctat
    40081 caaggttttt gaacacctga taggatgcct ttttatgata ttgaggcctt tttgcccttt
    40141 ttgaaaaact agaatagaaa caaaatatat aatagattga aactagaata gtacacatct
    40201 gcttctaaaa cattgttaga attcgatttg actgtcctga tcgatttgtc ctgttcttat
    40261 ttcattttga tatataaaaa atat
//
LOCUS       DAVLHM010000018        40279 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLHM010000018 DAVLHM010000000
VERSION     DAVLHM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.018"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            184..1164
                     /locus_tag="VXE45_000980"
     CDS             184..1164
                     /locus_tag="VXE45_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0789026.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            1969..2196
                     /locus_tag="VXE45_000981"
     CDS             1969..2196
                     /locus_tag="VXE45_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789027.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            2484..5381
                     /gene="nanA"
                     /locus_tag="VXE45_000982"
     CDS             2484..5381
                     /gene="nanA"
                     /locus_tag="VXE45_000982"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0789028.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            6396..6848
                     /locus_tag="VXE45_000983"
     CDS             6396..6848
                     /locus_tag="VXE45_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0789029.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            6867..8204
                     /locus_tag="VXE45_000984"
     CDS             6867..8204
                     /locus_tag="VXE45_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0789030.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            8283..9167
                     /locus_tag="VXE45_000985"
     CDS             8283..9167
                     /locus_tag="VXE45_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0789031.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            9167..10000
                     /locus_tag="VXE45_000986"
     CDS             9167..10000
                     /locus_tag="VXE45_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0789032.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            10018..12111
                     /gene="nanB"
                     /locus_tag="VXE45_000987"
     CDS             10018..12111
                     /gene="nanB"
                     /locus_tag="VXE45_000987"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0789033.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            12123..13226
                     /locus_tag="VXE45_000988"
     CDS             12123..13226
                     /locus_tag="VXE45_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0789034.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            13399..14097
                     /locus_tag="VXE45_000989"
     CDS             13399..14097
                     /locus_tag="VXE45_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0789035.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            14116..15633
                     /locus_tag="VXE45_000990"
     CDS             14116..15633
                     /locus_tag="VXE45_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0789036.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            15758..17086
                     /locus_tag="VXE45_000991"
     CDS             15758..17086
                     /locus_tag="VXE45_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0789037.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            17338..18204
                     /locus_tag="VXE45_000992"
     CDS             17338..18204
                     /locus_tag="VXE45_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0789038.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            18220..19059
                     /locus_tag="VXE45_000993"
     CDS             18220..19059
                     /locus_tag="VXE45_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0789039.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            19331..19783
                     /locus_tag="VXE45_000994"
     CDS             19331..19783
                     /locus_tag="VXE45_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0789040.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            19916..20224
                     /locus_tag="VXE45_000995"
     CDS             19916..20224
                     /locus_tag="VXE45_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789041.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            20234..20533
                     /locus_tag="VXE45_000996"
     CDS             20234..20533
                     /locus_tag="VXE45_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789042.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            20515..21159
                     /locus_tag="VXE45_000997"
     CDS             20515..21159
                     /locus_tag="VXE45_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0789043.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            21328..22245
                     /locus_tag="VXE45_000998"
     CDS             21328..22245
                     /locus_tag="VXE45_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0789044.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            22263..23147
                     /locus_tag="VXE45_000999"
     CDS             22263..23147
                     /locus_tag="VXE45_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0789045.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(23163..24014)
                     /locus_tag="VXE45_001000"
     CDS             complement(23163..24014)
                     /locus_tag="VXE45_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0789046.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            24214..26271
                     /gene="pbp2b"
                     /locus_tag="VXE45_001001"
     CDS             24214..26271
                     /gene="pbp2b"
                     /locus_tag="VXE45_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0789047.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            26282..26878
                     /gene="recR"
                     /locus_tag="VXE45_001002"
     CDS             26282..26878
                     /gene="recR"
                     /locus_tag="VXE45_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0789048.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            27054..28097
                     /locus_tag="VXE45_001003"
     CDS             27054..28097
                     /locus_tag="VXE45_001003"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0789049.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            28181..29554
                     /locus_tag="VXE45_001004"
     CDS             28181..29554
                     /locus_tag="VXE45_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0789050.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEAK"
     gene            29541..30152
                     /locus_tag="VXE45_001005"
     CDS             29541..30152
                     /locus_tag="VXE45_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0789051.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            30243..30947
                     /locus_tag="VXE45_001006"
     CDS             30243..30947
                     /locus_tag="VXE45_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0789052.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            31166..32539
                     /gene="ftsA"
                     /locus_tag="VXE45_001007"
     CDS             31166..32539
                     /gene="ftsA"
                     /locus_tag="VXE45_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0789053.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            32556..33815
                     /gene="ftsZ"
                     /locus_tag="VXE45_001008"
     CDS             32556..33815
                     /gene="ftsZ"
                     /locus_tag="VXE45_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0789054.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            33820..34491
                     /locus_tag="VXE45_001009"
     CDS             33820..34491
                     /locus_tag="VXE45_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0789055.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            34501..35040
                     /locus_tag="VXE45_001010"
     CDS             34501..35040
                     /locus_tag="VXE45_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0789056.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            35040..35303
                     /locus_tag="VXE45_001011"
     CDS             35040..35303
                     /locus_tag="VXE45_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0789057.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            35300..36085
                     /locus_tag="VXE45_001012"
     CDS             35300..36085
                     /locus_tag="VXE45_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0789058.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            36094..36882
                     /gene="divIVA"
                     /locus_tag="VXE45_001013"
     CDS             36094..36882
                     /gene="divIVA"
                     /locus_tag="VXE45_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0789059.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            37230..40022
                     /locus_tag="VXE45_001014"
     CDS             37230..40022
                     /locus_tag="VXE45_001014"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0789060.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEYVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPTQDAVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        12533 a         7048 c         8740 g        11958 t
ORIGIN      
        1 caaaaaacta gtataaacag aagagagagc gaaatgctct tttttcgttt ctaaaactac
       61 tttcagccca tcatcctaaa agtaaagaat ctaaattcac tttctattta cccttctttc
      121 ttgcattgat tacatagata tgctacagtt gtggtaacga ttacaaaata aaaggagcat
      181 gctatgaaaa atccagcttt gctagaagaa attaagacct atagaggaag ggatgaggtt
      241 ccggaagact ttgatgattt ctgggatggg gaagtgaaaa atgtttccac gcttccatcc
      301 taccacttgg aggaaagaga tttccacatt cctcaagtca agtgctatga gttaacattt
      361 gaaggaagca agaaaggaaa ggtctatgca cgcattgttc ttccaaagag tgaggagaag
      421 gttccactaa tcttccattt tcatggttat atgggacgtg gctgggactg ggccgacatg
      481 ctgggcttca ccgtagctgg ttacggtgtt gtttccatgg atgtgcgggg ccagtcaggt
      541 tactcacaag acggcttgcg ttctccttta ggaaataccg tgaaggggca tattatccgt
      601 ggtgctgtgg aaggtcggga ccacctcttt tataaggatg tttatctgga tatttaccag
      661 ttggtcgaaa ttgttgctag tctgtctcag gttgatgaga agcgtctttc tagctatggt
      721 gcctcacaag gaggggctct agctctagtt gcagcagcgc tcaatcctcg aattcagaaa
      781 acagttgcca tttatccctt cttgtcagac ttcagacggg tgattgagat tggtaatact
      841 agcgaggctt acgacgaact tttccgttat ttcaagtttc acgacccctt ccatgaaaca
      901 gaggaggaaa tcatggcgac ccttgcctat atcgatgtca aaaatcttgc ccatcgtatc
      961 caaggtgagg ttaagatgat tacgggcttg gacgacgatg tttgctatcc cattacccag
     1021 tttgcgattt ataatcgtct gacctgcgat aaaacctatc gcatcatgcc tgagtatgct
     1081 cacgaagcca tgaatgtatt tgtcaatgac caagtctaca actggctctg tggaagtgag
     1141 attcctttta aatatctaaa ataaggagtc gactctaagc acaaaatctt aaaaattaca
     1201 aacacgcata gtatcagggg attaagaaaa cttgatacta tgcgttttat catggaaata
     1261 tagtaaaatg aaacaagaac aggacaaatc gatcaggaga gtcaaatcga tttctaacaa
     1321 tgttttagaa gtagatgtgt actattctag tttcaatcta ttatatttat agaatttttt
     1381 gttgctagat ttgtcaaatt gcttaaaata atttttttca gaaagcaaaa gccgatacct
     1441 atcgagtagg gtagttcttg ctatcgttag gcttgtctgt aggtgttaat acttttcaaa
     1501 aatctcttca aaccacgtca gcttcgcctt gccgtatata tgttactgac ttcgtcagtt
     1561 ctatctgcca cctcaaaacg gtgttttgag ctgactttgt cagtcttatc tacaacctca
     1621 aaacagtgtt ttgagcatca tgcggctagc ttcttagttt gctctttgat tttcattgag
     1681 tataaaaaca gatgagtttc tgttttcttt ttatggacta taaatgttca gctgaaacta
     1741 ctttcaagga cattattata taaaagaatt ttttgaaact aaaatctact atattacact
     1801 atattgaaag cgttttaaaa atgaggtata ataaatttac taacacttat aaaaagtgat
     1861 agaatctatc tttatgtata tttaaagata gattgctgta aaaatagtag tagctatgcg
     1921 aaataacaga tagagagaag ggattgaagc ttagaaaagg ggaataatat gatatttaag
     1981 gcattcaaga caaaaaagca gagaaaaaga caagttgaac tacttttgac agtttttttc
     2041 gacagttttc tgattgattt atttcttcac ttatttggga ttgtcccctt taagctggat
     2101 aagattctga ttgtgagctt gattatattt cccattattt ctacaagtat ttatgcttat
     2161 gaaaagctat ttgaaaaagt gttcgataag gattgagcag gaagtatggt ataaatagca
     2221 taagctgatg tccatcattt gcttataaag agatatttta gtttaattgc agcggtgtcc
     2281 tggtagataa actagattgg caggagtctg attggagaaa ggagagggga aaattggcac
     2341 caatttgaga tagtttgttt agttcatttt tgtcatttaa atgaactgta gtaaaagaaa
     2401 gttaataaaa gacaaactaa gtgcattttc tggagtaaat gtcttatttc agaaatcggg
     2461 atatagatat agagaggatc agtatgaatc ggagtgttca agaacgtaag tgtcgttata
     2521 gcattaggaa actatcggta ggagcggttt ctatgattgt aggagcagtg gtatttggaa
     2581 cgtctcctgt tttagctcaa gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac
     2641 tttcggggga gagctcaacc ctaactgata cagaaaagag ccagccttct tcagagactg
     2701 aactttctgg caataagcaa gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa
     2761 gagattacta tgcacgagat ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg
     2821 aaaccaatgc ttcaaatggt cagagagttg atttatcaag tgaactagat aaactaaaga
     2881 aacttgaaaa cgcaacagtt cacatggagt ttaagccaga tgccaaggcc ccagcattct
     2941 ataatctctt ttctgtgtca agtgctacta aaaaagatga gtacttcact atggcagttt
     3001 acaataatac tgctactcta gaggggcgtg gttcggatgg gaaacagttt tacaataatt
     3061 acaacgatgc acccttaaaa gttaaaccag gtcagtggaa ttctgtgact ttcacagttg
     3121 aaaaaccgac agcagaattg ccaaatggtc gagttcgcct gtatgttaat ggtgttttat
     3181 ctcgaacaag tctgaaatct ggcaatttca ttaaagatat gccagatgta acgcatgtgc
     3241 aaatcggagc aaccaagcgt gccaacaata cggtttgggg gtcaaatcta cagattcgga
     3301 atctcactgt gtataatcgt gctttaacac cagaagaggt acaaaaacgt agtcaacttt
     3361 ttaaacgctc agatttagaa aaaaaactac ctgaaggagc ggctttaaca gagaaaacgg
     3421 acatattcga aagcgggcgt aacggtaaac caaataaaga tggaatcaag agttatcgta
     3481 ttccagcact tctcaagaca gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc
     3541 tccattcgag tgactggggt gatatcggta tggtcatcag acgtagtgaa gataatggta
     3601 aaacttgggg tgaccgagta accattacca acttacgtga caatccaaaa gcttctgacc
     3661 catcgatcgg ttcaccagtg aatatcgata tggtgttggt tcaagatcct gaaaccaaac
     3721 gaatcttttc tatctatgac atgttcccag aagggaaggg aatctttgga atgtcttcac
     3781 aaaaagaaga agcctacaaa gaaatcgatg gaaaaaccta tcaaatcctc tatcgtgagg
     3841 gagaaaagga agcttatacc attcgagaaa atggtactgt ctatacacca gatggtaagg
     3901 cgacagacta tcgcgttgtt gtagatcctg ttaaaccagc ctatagcgac aagggtgatc
     3961 tatacaaggg tgaccaatta ctaggaaata tctacttcac aacaaacaaa acttctccat
     4021 ttagaattgc caaggatagc tatctatgga tgtcctacag tgatgacgac gggaagacat
     4081 ggtcagcgcc tcaagatatt actccgatgg tcaaagccga ttggatgaaa ttcttgggtg
     4141 taggtcctgg aacaggaatt gtacttcgga atgggcctca caagggacgg attttgatac
     4201 cggtttatac gactaataat gtatctcact taaatggctc gcaatcttct cgtgtcatct
     4261 attcagatga tcatggaaaa acttggcatg ctggagaagc ggtcaacgat aaccgtcagg
     4321 tagacggtca aaagatccac tcttctacga tgaacaataa acgtgcgcaa aatacagaat
     4381 caacggtggt acaactaaac aatggagatg ttaaactctt tatgcgtggt ttgactggag
     4441 atcttcaggt tgctacaagt aaagacggag gagtgacttg ggagaaggat atcaaacgtt
     4501 atccacaggt taaagatgtc tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa
     4561 aagaatacat catcctcagt aatgcaggtg gaccgaaacg tgaaaatggg atggtccact
     4621 tggcacgtgt cgaagaaaat ggtgagttga cttggctcaa acacaatcca attcaaaaag
     4681 gagagtttgc ctataattcg ctccaagaat taggaaatgg ggagtatggc atcttgtatg
     4741 aacatactga aaaaggacaa aatgcctata ccctatcatt tagaaaattt aattgggaat
     4801 ttttgagcaa aaatctgatt tctcctaccg aagcgaaagt gaagcgaact agagagatgg
     4861 gcaaaggaga gatgggcaaa ggagttattg gcttggagtt cgactcagaa gtattggtca
     4921 acaaggctcc aacccttcaa ttggcaaatg gtaaaacagc gactttccta acccagtatg
     4981 atagcaagac cttgttgttt gcagtagata aggaagatat cggacaggaa attattggta
     5041 tagctaaagg aagcatcgaa agtatgcata atcttcctgt aaatctagca ggtgccagag
     5101 ttcctggcgg agtaaatggt agcaaagcag cggtgcatga agttccagaa tttacagggg
     5161 gagttaatgg tacagagcca gctgttcatg aaatcgcaga gtataaggga tctgattcgc
     5221 ttgtaactct tactacaaaa gaagattata cttacaaagc tcctcttgct cagcaggcac
     5281 ttcctgaaac aggaaacaag gagagtgacc tcctagcttc actaggacta acagctttct
     5341 tccttggtct gtttacgcta gggaaaaaga gagaacaata agagaagaat tctaaacatt
     5401 tgattttgta aaaatagaag gagatagcag gtttttaagc ctgctatctt tttttgatga
     5461 cattcaggct gatacgaaat cataagaggt ctgaaactac tttcagagta gtctgttcta
     5521 taaaatatag tagattgaaa taagatgtga acaactctat caggaaagtc aaattaattt
     5581 atagaaaaat tttagcagtc aaggtgtact gttataaatt caatatatta tacgactatt
     5641 aaccttatct tctcctaaaa ttgactttct tgttttctta tcttgtctac tcgaaacaag
     5701 tattgtaaga atttgattat ttttgaaagt acttttaata tacttgatat agttaaaaaa
     5761 gatttgaaac taaattccaa attagaaaaa gacttgaaat actaaaaaaa aaaagtatac
     5821 tctaattgaa aacggtaaca aaactaattt agagaatgaa atatagagta tttctctctt
     5881 aaaagttttt ggtgaaacga gatgtagaaa ggagatttag ccaaagagtc tattagtgct
     5941 agaataatag attagaatta ttttagaaaa acgaagtgag cagcttataa attcaagtcc
     6001 ccaaatagat tcatactagt atcttttgca aaaaataaag ggcgacttcc ttcatgaata
     6061 tcaatttcat ctataaggaa ggtagctaat tgaactaact tatttattct gtttgtcgct
     6121 agaaaaatca gacctccttg tgaagattga ggagatactg aatgaaaatc aaagaagaaa
     6181 ctagcaagct agtagcagat tgcccaaaac accgctttga ggttgtagat aagactgacg
     6241 tatataatcc aaggtgaagc gactgtggtt tgaagagatt ttcaaagagt ataggctaga
     6301 gagtagtgtt tttatgtcct tctagtagaa aatgctagac agaagaatgg ggaacttgga
     6361 taggaaaaat agattgagaa aggaggttag aagagatgat tattacaaaa attagccgtt
     6421 taggaactta tgtgggagta aatccacatt ttgcaacatt aatagatttt ttagaaaaaa
     6481 caggactaga aaatttaaca gaaggttcga ttgctatcga tggtaatcga ttgtttggga
     6541 attgctttac ttatctagca gatggtcaag caggggcttt ctttgaaaca caccaaaaat
     6601 atttggatat tcatttagtt ttggaaaacg aagaagccat ggctgttaca tcgccggaaa
     6661 atgtaagcgt tacccaagaa tatgatgaag agaaagatat tgaattatac acagggaaag
     6721 tggaacagtt ggttcatttg agagctggtg aatgcctcat cacttttcca gaagatttac
     6781 atcaacccaa ggttcgtata aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga
     6841 tttcttaatg tagaaagaga agaacgatga aaaaaatgag aaagttttta tgtctagctg
     6901 gaattgcgct agcggctgtt gccttggtag cttgttcagg aaaaaaagaa gctacaacta
     6961 gtactgaacc accaacagaa ttatctggtg agattacaat gtggcactcc tttactcaag
     7021 gaccccgttt agaaagtatt caaaaatcag cagatgcttt catgcaaaag catccaaaaa
     7081 cgaaaatcaa gattgaaaca ttttcttgga atgacttcta tactaaatgg actacaggtt
     7141 tagcaaatgg aaatgtgcca gatatcagta cagctcttcc taaccaagta atggaaatgg
     7201 tcaactcaga tgctttggtt ccgctaaatg attctatcaa gcgtattgga caagataaat
     7261 ttaacgaaac tgccttaaat gaagcaaaaa tcggagatga ttactactct gttcctcttt
     7321 attcacatgc acaagtcatg tgggttagaa cagatttgtt aaaagaacat aatattgagg
     7381 ttcctaaaac ttgggatcaa ctctatgaag cttctaaaaa attgaaagaa gctggagttt
     7441 atggcttgtc tgttccgttt ggaacaaatg acttaatggc aacacgtttc ttgaacttct
     7501 acgtacgtag tggtggagga agcctcttaa caaaagatct taaagcagac ttgacaagcc
     7561 aacttgctca agatggtatt aaatactggg ttaaattgta taaagaaatc tcacctcaag
     7621 attctttgaa ctttaatgtc cttcaacaag ctaccttgtt ctatcaagga aaaacagcat
     7681 ttgactttaa ctctggcttc catatcggag gaattaatgc caacagtcct caattgattg
     7741 attcgattga tgcttatcct attccaaaaa tcaaagagtc tgataaagac caaggaattg
     7801 aaacctcaaa cattccaatg gttgtttgga aaaattcaaa acatccagaa gttgctaaag
     7861 cattcttaga agcactttat aatgaagaag actacgttaa attccttgat tcaactccag
     7921 taggtatgtt gccaactatt aaggggatta gcgattctgc agcctataaa gaaaatgaaa
     7981 ctcgtaagaa atttaaacat gctgaagaag taattactga agctgttaaa aaaggtactg
     8041 ctattggtta tgaaaatgga ccaagtgtac aagctggtat gttaactaac caacacatta
     8101 ttgaacaaat gttccaagat atcattacaa atggaacaga tcctatgaaa gcagcaaaag
     8161 aagcagaaaa acaattaaac gatttatttg aggctgttca gtagatgtaa aagactagaa
     8221 aataggtggg ctagtgagct gaaaagctct agcccaatct tgtaaaagaa gggagaagga
     8281 gaatggttaa agaacgtaat ttaactcgct ggatatttgt tttgccagct atgattatcg
     8341 taggattact ctttgtttat ccgtttttct cgagtatttt ttatagcttt accaataagc
     8401 atttgattat gcctaattat aaatttgttg gtttggctaa ctataaagct gtgctgtcag
     8461 atcccaactt ctttaatgcg ttctttaatt caattaagtg gaccgttttc tcattagttg
     8521 gtcaagtttt agtagggttt gtattggctt tagctcttca cagagtacgc cacttcaaga
     8581 aattatatag gaccttattg attgttcctt gggcatttcc taccatcgtt attgccttct
     8641 cttggcagtg gattctaaac ggggtttatg gctacttacc taatctaatc gtaaaattag
     8701 gtttaatgga acatacacct gcatttttga cagatagtac atgggcattc ctatgtttgg
     8761 tgtttatcaa catttggttt ggagcaccaa tgattatggt taatgtgctt tcagctttgc
     8821 aaacagtacc agaagaacaa tttgaggctg ctaagataga tggtgcttca agttggcagg
     8881 tgttcaagtt tatcgtcttt ccacatatta aagtggttgt aggacttcta gttgttttga
     8941 gaactgtatg gatctttaat aactttgaca ttatctacct cattactggt ggtggaccag
     9001 ccaatgctac aacgacactt ccaatttttg cttacaacct gggttgggga actaaattgt
     9061 tgggtcgtgc ttcagcagtt acagtattgc tctttatctt cttggtggcg atttgcttta
     9121 tctactttgc tatcatcagt aagtgggaaa aggagggtag aaaataatga agaagaaatc
     9181 cagtatttat ttagatattc tctcacatgt acttttagtt ggtgcgacca tcgttgcaat
     9241 tttcccattg gtatggatta tcatatcttc tgtcaaaggg aaaggggaat taactcagta
     9301 tccaacacga ttttggcctg aacagtttac attagattat ttcactcatg ttatcaacga
     9361 tttgcacttc attgataaca ttcgaaacag tttaatcatt gccttggcta caaccctcat
     9421 tgcgattatt atttctgcta tggcagccta tggtattgtt cgattctttc ctaaattggg
     9481 agcaatcatg tcgagactac tcgtcattac ctacattttc ccaccaattt tgttagcaat
     9541 tccctattca attgccattg ctaaagttgg gttaacaaat agtttatttg gcttgatgat
     9601 ggtttatcta tcttttagtg ttccatatgc agtttggctc ttagttggat ttttccaaac
     9661 agttccaatt ggaattgaag aagcggctag aattgatggt gcaaataaat ttgttacgtt
     9721 ttataaggtt gtgctaccga ttgtagcacc aggtattgta gcaacagcta tttatacatt
     9781 tatcaatgct tggaatgaat tcctgtatgc cttgatttta attaacaata caggaaagat
     9841 gacagtagca gtagcccttc gttcacttaa tggttcagaa atactagact ggggagatat
     9901 gatggcagcg tctgttattg tagttcttcc atcaattatt ttcttctcta tcatccaaaa
     9961 taagattgca agtggattat cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg
    10021 aataaaagag gtctttattc aaaactagga atttctgttg taggcattag tcttttaatg
    10081 ggagtcccca ctttgattca tgcgaatgaa ttaaactatg gtcaactgtc catatctcct
    10141 atttttcaag gaggttcata tcaactgaac aataagagta tagatatcag ctctttgtta
    10201 ttagataaat tgtctggaga gagtcagaca gtagtaatga aatttaaagc agataaacca
    10261 aactctcttc aagctttgtt tggcctatct aatagtaaag caggctttaa aaataattac
    10321 ttttcaattt tcatgagaga ttctggtgag ataggtgtag aaataagaga cgcccaaaag
    10381 ggaataaatt atttattttc tagaccagct tcattatggg gaaagcataa aggacaggca
    10441 gttgaaaata cactagtatt tgtatctgat tctaaagata aaacatacac aatgtatgtt
    10501 aatggaatag aagtgttctc tgaaacagtt gatacatttt tgccaatttc aaatataaat
    10561 ggtatagata aggcaacact aggagctgtt aatcgtgaag gtaaggaaca ttacctcgca
    10621 aaaggaagta ttggtgaaat cagtctattt aacaaagcaa ttagtgatca ggaagtttca
    10681 aatattccct tgtcaaatcc atttcagtta attttccaat caggagattc tactcaagct
    10741 aactatttta gaataccgac actatataca ttaagtagtg gaagagttct atcaagtatt
    10801 gatgcacgtt atggtgggac tcatgattct aaaagtaaga ttaatattgc cacttcttat
    10861 agtgatgata atgggaaaac gtggagtgag ccaatttttg ctatgaagtt taatgactat
    10921 gaggagcagt tagtttactg gccacgagat aataaattaa agaatagtca aattagtgga
    10981 agtgcttcat tcatagattc atccattgtt gaagataaaa aatctgggaa aacgatatta
    11041 ctagctgatg ttatgcctgc gggtattgga aataataatg caaataaagc cgactcaggt
    11101 tttaaagaaa taaatggtca ttattattta aaactaaaga agaatggaga taacgatttc
    11161 cgttatacag ttagagaaaa tggtgtcgtt tatgatgaaa caactaataa acctacaaat
    11221 tatactataa atgataagta tgaagttttg gagggaggaa agtctttaac agtcgaacaa
    11281 tattcggttg attttgatag tggctcttta agagaaaggc ataatggaaa acaggttcct
    11341 atgaatgttt tctacaaaga ttcgttattt aaagtgactc ctactaatta tatagcaatg
    11401 acaactagtc agaatagagg agagagttgg gaacaattta agttgttgcc tccgttctta
    11461 ggagaaaaac ataatggaac ttacttgtgt cctggacaag gtttagcatt aaaatcaagt
    11521 aacagattga tttttgcaac atatactagt ggagaactaa cctatctcat ttcggatgat
    11581 agtggtcaaa catggaagaa atcctcagct tcaattccgt ttaaaaatgc aacagcagaa
    11641 gcacaaatgg ttgaactgag agatggtgtg attagaacat tctttagaac cactacaggt
    11701 aagatagctt atatgactag tagagattct ggagaaacat ggtcgaaagt ttcgtatatt
    11761 gatggaattc aacaaacttc atatggcaca caagtatctg caattaaata ctctcaatta
    11821 attgatggaa aagaagcagt cattttgagt acaccaaatt ctagaagtgg ccgtaaggga
    11881 ggccaattag ttgtcggttt ggtcaataaa gaagatgata gtattgattg gagataccac
    11941 tatgatattg atttgccttc gtatggttat gcctattctg cgattacaga attgccaaat
    12001 catcacatag gtgtactgtt tgaaaaatat gattcgtggt cgagaaatga attgcattta
    12061 agcaatgtag ttcagtatat agatttggaa attaatgatt taacaaaata aaggagaaaa
    12121 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
    12181 tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
    12241 ttgcagaaga attgggagca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
    12301 aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
    12361 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
    12421 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
    12481 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
    12541 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaactg tcagtatcat
    12601 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
    12661 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
    12721 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
    12781 ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg
    12841 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
    12901 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
    12961 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
    13021 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
    13081 agattatgga aggagctcca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
    13141 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
    13201 taaaattgtc agaaattgta aaataaattt tggtattctc ctattatagg tcgacttgct
    13261 cctctgaaag tacttttaga ggagctgttt gacttggcta gtttttgaaa ctgaaatcta
    13321 ttatactaca aactattgaa agcgttttaa ttttaaggta taataatctc atagaaataa
    13381 agaaaaggag gaaagaggat gccacagatt agcaaagaag ccttgattga gcaaatcaaa
    13441 gatggaatca tcgtttcttg tcaggctctt cctcatgaac cgctttatac agaagcggga
    13501 ggggtgattc ccttgctggt caaagcggct gagcaaggtg gagcagtcgg tatccgagca
    13561 aacagtgttc gcgatatcaa ggaaattaag gaagtcacta aacttccaat cattgggatt
    13621 atcaaacgtg attatccacc tcaggaaccc ttcatcacgg ctactatgaa agaagttgat
    13681 gaattggcag aactggacat cgaggtgatt gctctggatt gtaccaagcg tgaacgctac
    13741 gatggtttgg aaattcaaga gttcattcgt caggttaagg agaaatatcc taatcagctt
    13801 ttgatggctg atactagtat cttcgaagaa gggctagcag ctgtagaagc aggaattgac
    13861 tttgtcggaa caaccttatc aggctacaca tcctacagtc caaaagtaga cggtccagat
    13921 tttgaattga ttaagaaact ctgtgatgcc ggtgtagatg tcattgcaga aggaaaaatt
    13981 catacaccag aacaagccaa acaaatcctt gaatatggag tgcgaggcat cgttgttggt
    14041 ggcgccatta ctagaccaaa agagattaca gaacgcttcg ttgctagtct taaataagat
    14101 gtgaggggga gttttatgtt taaagtttta caaaaagttg gaaaagcttt tatgttacct
    14161 atagctatac ttcctgcagc aggtctactt ttggggattg gtggtgcact ttcaaaccca
    14221 accacgatag caacttatcc aatactagac aatagtattt ttcaatcaat attccaagta
    14281 atgagctctg caggagaggt tgtattcagt aatttgtcac tacttctctg tgtgggatta
    14341 tgtattggct tagcgaaacg agataaagga accgctgcgt tagcaggagt aactggttac
    14401 ttagttatga ctgcaacgat caaagctttg gtaaaacttt ttatggcaga aggatctgca
    14461 attgatactg gagttattgg agcattagtt gtcggaatag ttgccgtata tttgcacaac
    14521 cgatataaca atattcaatt accttccgct ttaggattct ttggaggttc acgcttcgtt
    14581 cctattgtta catcgttctc ttctatcttg attggctttg tcttctttgt tatttggcca
    14641 cctttccaac aacttcttgt ttctacaggt ggatatattt ctcaggcggg tccaattgga
    14701 acttttctat atggattttt aatgagactt tctggagcag taggcttaca tcatataatt
    14761 taccctatgt tttggtatac tgaacttggt ggtgttgaaa ctgttgcagg acaaacagtg
    14821 gttggagctc aaaaaatatt ttttgctcaa ttagccgatc cggcccattc tggattattt
    14881 acagaaggaa caaggttttt tgcaggtcgt ttctcaacaa tgatgttcgg tttaccggct
    14941 gcctgtttag cgatgtacca tagtgttcct aaaaatcgtc gtaaaaaata cgcgggtttg
    15001 ttttttggag ttgctttaac atcttttatt accggtatta cagaaccaat tgaatttatg
    15061 tttctattcg tcagtccggt tctatatgtt gttcacgcat tccttgatgg tgttagcttc
    15121 tttattgcag acgtcttaaa tatttcaata ggaaacacat tttcaggagg tgtaatcgat
    15181 ttcactttat ttggaatttt gcaggggaac gctaagacga attgggttct tcagattcca
    15241 attggactta tttggagtgt tttgtattat attattttta gatggttcat tactcaattc
    15301 aacgttctaa cgccaggacg aggagaagaa gtagattcta aagaaatttc tgaatccgca
    15361 gattcaactt caaatactgc agattattta aaacaggata gcctacaaat tatcagagcc
    15421 ttgggtggat caaataatat agaagatgta gatgcttgtg tgacacgttt acgtgtagct
    15481 gtaaaagaag ttaatcaagt tgataaagca cttttaaaac aaattggtgc agttgatgtc
    15541 ttagaagtga agggtggcat tcaagcaatc tatggagcaa aagcaatctt atataaaaat
    15601 agtattaatg aaattttagg tgtagatgat taagtactta ctgacttaat aaaaaacaga
    15661 ggagagtgat ggatgagtag gatgaaatga aatcgcatac aagaaataaa gaactcatta
    15721 tccaagttgg atacgcttat tacataggag aatacaaatg aaatttagaa aattagcttg
    15781 tacagtactt gcgggtgctg cggttcttgg tcttgctgct tgtggcaatt ctggcggaag
    15841 taaagatgct gccaaatcag gtggtgacgg tgccaaaaca gaaatcactt ggtgggcatt
    15901 cccagtattt acccaagaaa aaactggtga cggtgttgga acttatgaaa aatcaatcat
    15961 cgaagcgttt gaaaaagcaa acccagatat aaaagtgaaa ttggaaacca tcgacttcaa
    16021 gtcaggtcct gaaaaaatca caacagccat cgaagcagga acagctccag acgtactctt
    16081 tgatgcacca ggacgtatca tccaatacgg taaaaacggt aaattggctg agttgaatga
    16141 cctcttcaca gatgaatttg ttaaagatgt caacaatgaa aacatcgtac aagcaagtaa
    16201 agctggagac aaggcttata tgtatccgat tagttctgcc ccattctaca tggcaatgaa
    16261 caagaaaatg ttagaagatg ctggagtagc aaaccttgta aaagaaggtt ggacaactga
    16321 tgattttgaa aaagtattga aagcacttaa agacaagggt tacacaccag gttcattgtt
    16381 cagttctggt caagggggag accaaggaac acgtgccttt atctctaacc tttatagcgg
    16441 ttctgtaaca gatgaaaaag ttagcaaata tacaactgat gatcctaaat tcgtcaaagg
    16501 tcttgaaaaa gcaactagct ggattaaaga caatttgatc aataatggtt cacaatttga
    16561 cggtggggca gatatccaaa actttgccaa tggtcaaaca tcttacacaa tcctttgggc
    16621 accagctcaa aatggtatcc aagctaaact tttagaagca agtaaggtag aagtggtaga
    16681 agtaccattc ccatcagacg aaggtaagcc agctcttgaa taccttgtaa acgggtttgc
    16741 agtattcaac aataaagacg acaagaaagt cgctgcatct aagaaattca tccagtttat
    16801 cgcagatgac aaggagtggg gacctaaaga cgtagttcgt acaggtgctt tcccagtccg
    16861 tacttcattt ggaaaacttt atgaagacaa acgcatggaa acaatcagcg gctggactca
    16921 atactactca ccatactaca acactattga tggatttgct gaaatgagaa cactttggtt
    16981 cccaatgttg caatctgtat caaatggtga cgaaaaacca gcagatgctt tgaaagcctt
    17041 cactgaaaaa gcgaacgaaa caatcaaaaa agctatgaaa caatagtcct tagttattct
    17101 ataaaaagta gttttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
    17161 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
    17221 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
    17281 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
    17341 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
    17401 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
    17461 tttgagtttg taggcttgga taactatatc cgtatgttta aagatcctgt ctttacaaaa
    17521 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
    17581 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
    17641 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
    17701 tatgacccac tatcagggat tctaaacttt gtccttaagt ccagccacat catcagccaa
    17761 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
    17821 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
    17881 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ttggaagatt
    17941 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
    18001 ttccagtgtt ttgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
    18061 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
    18121 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
    18181 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
    18241 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
    18301 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
    18361 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
    18421 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
    18481 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
    18541 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
    18601 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
    18661 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
    18721 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
    18781 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
    18841 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
    18901 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
    18961 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
    19021 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
    19081 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
    19141 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
    19201 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
    19261 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
    19321 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
    19381 taatttagac aaggctatcg actatctcta ccaacatcgt aaggattctt tcgaattagg
    19441 aaagtatgat attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
    19501 agctgaaaat gatcaatttg agtatcataa gaactatgca gatttgcatt tgctggtaga
    19561 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
    19621 agcgagtgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
    19681 caattttgcg attttcttcc caggtgagcc acatcagcca aatggttatg caggcatgga
    19741 agaaaaggtt cggaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
    19801 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagggaaatg
    19861 agaataaaat atttaaaaat tggtatcttc taagtatgct gcaagagcta gtttcttgga
    19921 tggacaggga attacagttg atgagatggc ttggataatt aggggcattg tgaatggatt
    19981 gattggtaga tacataaaat taggtactta tgcagccaag tatggtatta gtatggcgcg
    20041 ttcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattat cgaccaagat
    20101 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
    20161 caatattgct gcagcttggg atgcacatga taaaattcct aacaatggtc gtataaactt
    20221 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
    20281 gcttgcaatg ataattcgtg gagggctaga tggatttgat gagcatactt ggagtactat
    20341 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
    20401 gtccaaaaga aaaaagaaaa aagaaaaaat agatttgttc atggtaggga cttatgaaag
    20461 ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc aaacatggca
    20521 caaaaaggag taagccttat caaggcagca tttgatacag acaactttct catgcgtttt
    20581 agtgagaaag tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc ttgtttgccc
    20641 atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga agttaagaag
    20701 agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa tctgaaacta
    20761 ggtcttcagc tgggtttaat ggagttagga attgtgtttc ttaccctttc agatctctat
    20821 cttttctggg gtcaaacagc tctgcccttc caattgctga aagccatttg tttaggtatt
    20881 ctgatttttc ttactatcgt gatgctggct agttacccta tcgcggcacg ttatgaccta
    20941 tcttggaaag aaattcttca aaaaggattg atgttggcta gttttaactt tccttggttc
    21001 ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc cgccttcagt
    21061 ctactcttag gtggctcagt cttcttactt tttgggtttg gactattggt ctttatccag
    21121 actggattga tggagaaaat tttcgcaaaa taccaatagg agccttattt ctgaaactac
    21181 tttcaaacgc tccaaacgct attctataag cgagaaacta aaatctaagt gtctataaga
    21241 tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc tgctttagca
    21301 gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga aggtgtcatt
    21361 ccagccttct acgcatgtta tgatgaacaa ggagaagtaa gcccagaacg tacgcgtgcc
    21421 ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg ttcttctggt
    21481 gaatgtatct accaaagtgt tgaagaccgc aagttaatct tggaagaagt catggcggta
    21541 gccaaaggta aattgaccat cattgctcat gttgcctgca acaatactaa agatagtatg
    21601 gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat tccaccaatt
    21661 tatttccgct tgccagaata ctcagttgcc aaatactgga acgatatcag ttctgcagct
    21721 ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc tttgactcca
    21781 agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgttaagaa ctcttctatg
    21841 ccagttcaag atatccaaac ctttgtcagc cttggtgggg aagaccatat cgtctttaat
    21901 ggtcctgatg agcagttcct aggaggacgc ctcatgggtg ctagggctgg tatcggtggt
    21961 acttatggtg ctatgccaga actcttcttg aaactcaatc agttgattgc ggataaggac
    22021 ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa tcattggtaa actcacttct
    22081 gctcatggaa atatgtacgg tgtcattaaa gaagtcttga aaatcaatga aggcttgaat
    22141 attggatctg ttcgttcacc attgacacca gtgactgaag aagatcgtcc agttgtagaa
    22201 gcggctgctg ccttgattcg tgaaaccaag gagcgcttcc tctaatctaa aaggaggtat
    22261 ttatgacata ctacgttgca attgatatcg gtggaaccaa catcaagtat ggtttggttg
    22321 atcaagaggg gcaacttctt gaatcgcatg aaatgccaac tgaggcgcat aagggtggac
    22381 ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa ggcccagtag
    22441 caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag attttctatg
    22501 ctgggcctca aatccctaac tacgcaggca cccagttcaa aaaggaaatc gaagaaagct
    22561 ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct gaggcagtat
    22621 ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaacc ggtatcggtg
    22681 gttgcttgat tatggatagg aaagtcttcc atggttttag caattcagcc tgtgaagtcg
    22741 ggtatatgca tatgcaggat ggagcttttc aggatctcgc ttctacaaca gctttagtga
    22801 aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccga cgtatcttta
    22861 aggaagctac tgaaggaaac aaaatctgca tggaaggtat tgaccgtatg gttgactatc
    22921 taggaaaagg tctggcaaat atttgttatg tggccaatcc agaagtggtt attcttggtg
    22981 gtggtatcat ggggcaagag gctatcctca aacctaagat ccgcacagcc ttgaaagagg
    23041 cattggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac caaaatacag
    23101 cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt ggctcagcca
    23161 aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt attttcccag
    23221 tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta ggcataaatc
    23281 aaatcgataa agaagagcat aggaagttga gcggatattc gttggatgta ggagggttgg
    23341 ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatctttatt gggaacactt
    23401 gtaaagagta cagtctttgc ccccatctcc ttggcatcta atagactatc taaaatagaa
    23461 ggagttgagc ctgaaagtga gaaacccagt actagacaat tttcatccat gatgctggtt
    23521 gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctag tcgcataaaa
    23581 cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccaaagaa gtagatacgc
    23641 tcagcatctt cgattagctg ggcaattcgc tctagttgga tttcgtcaat caagtcttgt
    23701 gtttgttccc tcatattgct ataacttctg aggactcgtt tggtcagtgg actatgcttg
    23761 gagacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa ttctcggtag
    23821 ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat atgtaatttt
    23881 tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa aaaatagcga
    23941 gcgatttctt gctctaggtc tgtcatttct tcaaaatgtg aatcaatgat agttgcgata
    24001 tctggtttgt ccatagggaa agctccttta catgggtcat actggaagac tagatcaggg
    24061 aatagtcaca cttcattata acacataata taaggataga taaataaaaa cgcatctctg
    24121 ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc ataattttct actcaaattg
    24181 tggtacaatt aagagtaaga ttttaagtta gaaatgagac tgatttgtat gagaaaattt
    24241 aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat tttactcttt
    24301 atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt ttacgaaaaa
    24361 aagctagcct cagctagtca gaccaagatt acaagcagtt cagcccgtgg ggaaatttat
    24421 gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc ctttacgcgt
    24481 agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact gacttatgtg
    24541 agcatcagtt ctccaaattt gacagaacgc cagctggcgg attactattt ggctgatcct
    24601 gaaatctata aaaaaacagt ggaagctctc ccaagtgaga aacgcttgga ttcagatggc
    24661 aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtcca aacaagtcaa
    24721 ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt aaatgctgtt
    24781 ggaaactttg cgacaggaac cattgctaca gatcctctaa atgattctca ggtggctgtt
    24841 attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg ggatagaaag
    24901 gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa agctggtctc
    24961 ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga tcgtgtagga
    25021 acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc ggtaaaagaa
    25081 atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga aggtagtaag
    25141 ggaaacaata tcaaactgac cattgatttg gctttccaag atagcgtgga tgctttactg
    25201 aaaagttatt tcaattccga gctagaaaat ggtggagcca agtattctga aggtgtctat
    25261 gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat taaacatgac
    25321 ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt ctttgttcca
    25381 ggttcggttg tcaaggcggc gaccatcagc tcaggttggg aaaatggagt cttgtcagga
    25441 aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat caattcttgg
    25501 tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga gtattcatca
    25561 aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca acccaatatg
    25621 tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac ctttggcgaa
    25681 tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg atttgttccc
    25741 aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga taactatacg
    25801 ccgatgcagt tggctcagta tgtagcaact attgcaaata atggtgttcg tgtggctcct
    25861 cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga cttgattcag
    25921 caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat gagcatcttg
    25981 caccaaggtt tttatcaggt tgcccatggt actagtggat tgacaactgg acgtgccttt
    26041 tcaaatggcg ccttggtatc cattagcgga aaaacaggta cagccgaaag ctatgtggca
    26101 gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga taatccccaa
    26161 atcgctgttg cagtggtctt tcctcataat accaatctaa caaatggtgt aggaccttcc
    26221 attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaacta gaaaggaaat
    26281 tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt taccaggtat
    26341 cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg ctgatgatgt
    26401 caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt gttctatttg
    26461 tggacgtttg acagacgacg atccttgttc tatctgtact gatccgactc gtgaccagac
    26521 aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata tccaagaata
    26581 ccatggactc tatcatgtcc ttcatggcct catttctcct atgaatggta tcagtccgga
    26641 cgatatcaat ctcaagagcc ttatgactcg tcttatggat agtgaagttt cagaagtgat
    26701 tgtggcgact aatgctacag cggatggtga agcgacttcc atgtatcttt cacgtttgct
    26761 caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg gagcggacat
    26821 tgagtatgcg gacgaagtga cactcttacg agcgattgaa aatcggacag agttgtaagt
    26881 gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga aaatcgttcc
    26941 tatcggcctc tttttgtata gtgtgatgag taggatcagg ttcaagtttt aaaaaaccaa
    27001 gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat aatatgaaac
    27061 aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct gtcctttcag
    27121 ctgagagtgt catgcgtgcg gtcaattacg accgtttcac agtcaagact ttctttatca
    27181 gtcagtcagg tgactttatc aaaacacagg aatttagtca tgctccgggg caagaagacc
    27241 gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt gctatctacg
    27301 aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat ggctctgttc
    27361 aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg tcatcaagtc
    27421 ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt gcccaagttc
    27481 cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatcgctgaa gtggaagaaa
    27541 aattggctta tccagtcttc actaagccgt caaacatggg gtctagtgtc ggtatttcta
    27601 agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga tatgacagcc
    27661 gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc ttgggtaact
    27721 acgatgtcaa gagcacgcta cctggagaag ttgtcaagga cgttgccttt tatgactacg
    27781 atgccaagta tattgataac aagattacta tggatattcc tgccaaaatc agtgatgatg
    27841 tggtggctgt catgcgtcaa aatgcagaaa cagccttccg tgccattggt ggccttggtc
    27901 tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac gagctcaata
    27961 ccatgccagg ttttacccag tggtctatgt acccactact ttgggacaat atggggatca
    28021 gctacccaga actaatcgag cgtttggttg accttgccaa ggaaagtttt gacaagcgcg
    28081 aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac tgcacggtga
    28141 ctagagttct cggacttcag ccctttttaa aggagtagaa atgaaattaa caatccatga
    28201 aattgcccaa gttgttggag ccaaaaatga tatcagtatc tttgaggaca cccagttaga
    28261 aaaagctgag tttgatagtc gtttgattgg aactggagat ttatttgtgc cacttaaagg
    28321 tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag cagtaacctt
    28381 gtctgagaaa gaggtctcaa atcatcctta cattctagta gatgatgttt tgacagcctt
    28441 tcaatcccta gcatcctact atcttgaaaa aacgactgtt gatgtctttg ctgttacagg
    28501 ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa caagatacaa
    28561 gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca cagttcttca
    28621 tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact tgggagatat
    28681 tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg ttggagaagc
    28741 tcatttggcc tttttcaaag atcgttctga gattgctaaa ggaaaaatgc aaattgcaga
    28801 cggaatggct tcaggttcct tgcttttagc gccggctgac cctatcgtag aggactattt
    28861 gccaactgat aaaaaggtgg ttcgttttgg tcaaggagca gagctgggaa ttaccgactt
    28921 ggttgagcgc aaagatagtc tgaccttcaa ggtcaatttc ttagagcaag cccttgattt
    28981 gccagtaact ggcaagtaca atgcgacaaa tgctatgatt gcatcctatg ttgccttgca
    29041 agaaggagtt tcagaggagc aaattcgttt ggccttccaa catcttgaat tgacgcgtaa
    29101 ccgtaccgag tggaagaaag cagccaatgg agcagatatc ctgtcagatg tttataatgc
    29161 caatccaact gctatgaaac tgattttaga gactttctct gccattccag ccaatgaagg
    29221 tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt ctgttcaact
    29281 tcataatcag atgattttga gcctctcccc agatgtgctt gatatcgtta ttttctatgg
    29341 agaagatatt gctcagttgg ctcaattggc cagtcaaatg tttccaatcg gccacgttta
    29401 ctacttcaag aaaacagaag accaggatca atttgaagac ctagtcaagc aggttaagga
    29461 aagccttgga gcctatgacc aaatcttgct aaaaggttct aactctatga atctagccaa
    29521 attggtagaa cgtttagaaa atgaagccaa gtgattttgt caagtatctg caaagaatga
    29581 ttgcccttac agatactggc ttaaccttta caaaagatcc ttttgaccgt gagcgctacg
    29641 aggacttgcg aagtctgtta tctgaaatgt tgaatcaggg atcagacctg gatgcagaag
    29701 aagtagcaga agtcttgaaa ccaacttcag cttatgcgac tcccttaatg gacgtccgtg
    29761 cttggattgt tgaggatgag aagatttgtc tggttagggg acaaggagag gatagttggg
    29821 ctttgccagg tggctttggt gaagtcggct attctccaac tgaaaatatt ctcaaggaaa
    29881 ttgaagaaga aaccggtttt aaagccaaag ttgaaagact gctagctgtt tttgatacca
    29941 atcgtttcca actacagagt aaacaatatg caaagtttgt ttttgaatgt aagtttctcg
    30001 atggacaatt ccaagaaaat caagaaattg cagaccttca attttttgcc attgatcaac
    30061 tgccagcctt atctgaaaaa cgcattacca aggagcaaat cgagattctt tggcaggttt
    30121 atcaaggtca gagggagcaa tatcttgact aagaagatga ttatcgtatt tttaaatcca
    30181 tttttaacaa ctagcatggt ataataatat gcaggaaaat tttgaattat gaggaagact
    30241 agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc aaatttgacc
    30301 ttttttggta tgttagccta tttacgctct tagccttaac cttttataca gcccatcgct
    30361 atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt cagttaatcc
    30421 ttctttatgg ttggtactgg gtcaatcata tgccactgtc agaaagccta cccttttacc
    30481 attgccgtat ggctatgttt gtggtactct tgcttcctgg tcagtccaaa tataaacaat
    30541 actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca gtgccagatg
    30601 cttacccttt tccacatatc accattctat cctttatctt tggtcattta gcactcttgg
    30661 ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat gtgaagggaa
    30721 tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg gtgacaggtg
    30781 gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta gtagctaatt
    30841 atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa atcttagaat
    30901 tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac agagctttct
    30961 tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct gaatagacaa
    31021 actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt ttttgtgtta
    31081 taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa gtgcgaaact
    31141 tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag gtctagatat
    31201 tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat taaatgtaat
    31261 tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg atattgatgc
    31321 agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag gcatttcgat
    31381 taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa ctcaggggat
    31441 gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa atgttgtcaa
    31501 atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta ttcctgaaga
    31561 atttattgtg gatggtttcc aagggattcg tgacccacgt ggtatgatgg gggttcgcct
    31621 tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt tgcgtaagac
    31681 ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag caatggttca
    31741 gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata tgggggcagg
    31801 tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata ttctccaaga
    31861 aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc gcaaattagc
    31921 ggaaggcttg aaactgaatt acggggaagc ctatccgcct cttgcaagca aagaaacctt
    31981 ccaagtagag gttattggag aagtggaagc agtcgaagtg acggaagcct acttgtcaga
    32041 aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat tagatagaag
    32101 gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca ttttaccagg
    32161 tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg ttccaaatca
    32221 agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat ttgcgggtca
    32281 attaacagaa gttaatcttt tggctcaggg agcgataaaa ggtgagaatg acttaagtca
    32341 tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac aatcaacgcc
    32401 tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac caatggcgga
    32461 tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg gcttgatcgg
    32521 aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt gatacagctg
    32581 ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc aatgccatca
    32641 accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac acagatgtac
    32701 aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa ttgactcgtg
    32761 gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa agcgaagaaa
    32821 cactgacgga agctattagt ggtgccgata tggtcttcat cactgctggt atgggaggag
    32881 gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta ggtgcgctta
    32941 cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga caatttgctg
    33001 tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc tcaaacaaca
    33061 atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc gaagcggata
    33121 acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca ggattgatta
    33181 accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct cttatgggta
    33241 ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca atctattcac
    33301 cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt actggtggtc
    33361 ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag gcagcaggtc
    33421 aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat gaaattcgtg
    33481 taacagttgt cgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg gctccacaag
    33541 ctagaactgc tactaactac cgtgagacag tgaaaccagc tcattcacat ggctttgatc
    33601 gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt cgtttggaac
    33661 caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt gttcgtacaa
    33721 cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa gatgaagatg
    33781 aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa agaaaataca
    33841 gaacttgttt ttcgagaagt tgcagaggct agtctgagtg ctcatcgaga gagtggttcg
    33901 gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc cttgcttccg
    33961 ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa atatgaagct
    34021 ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg taaggtgaaa
    34081 gatatcattc aatacgttga ttatttccat gcattggact cagtaaagct agcaggggaa
    34141 attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat ttctaaagaa
    34201 gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga gttagccaga
    34261 ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc tagcagtgag
    34321 cagttgaaag agattttcaa ggcgacccaa gatttacaaa gagaaattca agagaaacaa
    34381 attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta taaagaagcg
    34441 attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta ggagagaacc
    34501 atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga tgaggattca
    34561 agtctccctt atgaaaaaag agatgagcct gtgtttactc cagtaaattc ttcacaggaa
    34621 ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa caatatcacc
    34681 agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac ggataaggtc
    34741 attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt tgatttattg
    34801 gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca ggctcgtcgt
    34861 tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa aaaggtagct
    34921 tctaccatgt atttgttgac accagtgaat gttattgtaa atgttgaaga tatccgttta
    34981 ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag agtacgataa
    35041 tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg attttggtag
    35101 ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt cgttggattg
    35161 tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag atagcgggtc
    35221 ttgatttatc tgtttgggtc gcgattgttt tggttcgatt tttaggagaa aacctagtgc
    35281 gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca tagaagatcg
    35341 tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct atgctccttt
    35401 tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg ccaaaaccta
    35461 tggtcttgct tgtagcagta gtggggaatt cgtctcgagt gagtatgttc gagttttatt
    35521 atacccagat tatttccaac cagagttttc agattttgaa atatctctcc aggaaattgt
    35581 gtattccaat aaatttgaac atttaacgca tgctaagatt ttagggacag tcatcaatca
    35641 attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac gggcgcagat
    35701 tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa ttggtcgtat
    35761 acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag aacagtatcg
    35821 agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa atgttttgaa
    35881 actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag taaattatca
    35941 tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg tgagaaaatt
    36001 tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga aaaaaataac
    36061 cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt agaaataaag
    36121 gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga tgaattttta
    36181 gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa aaatttgcgt
    36241 attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc attgagccag
    36301 tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca tgaacgttca
    36361 aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga agctaaatat
    36421 aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc tgttgaaaca
    36481 gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac aattgagagt
    36541 cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac agctacttat
    36601 cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg agaaccgatt
    36661 ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca agcagaaatg
    36721 gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt tgaagctcag
    36781 attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga agaagagcct
    36841 ctgctcatcc agttggccca atgtatgaag aaccagaagt agctccagtg catccgacag
    36901 gtccaacacc agctacagaa actgttgatt cagcaccagg atttgaagca ccgcaagaat
    36961 ccgttacaat tttataagaa acgatgtgag aacaatatct tatccttata tttccagcga
    37021 gcaggagatg gtgtgagtcc tgcattccct aacgataaga ttatcctctc aaaaactcaa
    37081 gtctgaatct agtaagattt gacgtttccc acgttacggg ataagaggga gaaagactaa
    37141 atctttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt cgtggttttt
    37201 aatttgttat tatttataaa ggagatacca tgaaactaaa agataccctt aatcttggga
    37261 aaacagcttt cccaatgcgt gcaggccttc cgaccaaaga gccagtttgg caaaaggaat
    37321 gggaagatgc aaaactttac caacgtcgtc aagaactaaa tgaagggaaa ccgcattttg
    37381 tcttgcatga tggccctcca tacgcaaacg gaaatatcca cgttggacat gccatgaatc
    37441 atatctcaaa agatatcatc attcgttcta agtctatgtc aggttttaac gcaccttata
    37501 tcccaggttg ggatactcat ggtctgccaa tcgagcaagt tttggcaaag caaggtgtga
    37561 agcgcaaaga aatggacttg gttgagtact tgaaactttg ccgtgaatac gctctttctc
    37621 aagtttataa acaacgtgat gatttcaagc gcttggggat gtcaggtgac tgggaaaatt
    37681 tatatgtgac tttaactcca gactacgaag cagcccaaat ccgtgtattt ggtgagatgg
    37741 ctaataaggg ttatatctac cgtggtgcta agccagttta ctggtcttgg tcatctgagt
    37801 cagcccttgc cgaagcggaa attgaatacc atgatttggt ttcaacttcc ctttactatg
    37861 ccaataaggt aaaagatggc aaaggtgttc tagatacaga tacttatatc gttgtttgga
    37921 caactactcc atttactatc acagcttctc gtggtttgac tgttggtgca gatattgatt
    37981 acgttttggt tcaacctgct ggtgaaactc gtaagtttgt cgttgctgca gaattgttga
    38041 ctagcttgtc tgagaaattt ggctgggttg atgttcaagt tttggcaact taccgtggtc
    38101 aagaactcaa ccacatcgta acagaacatc catgggatac agctgtagat gaattggtta
    38161 tccttggtga ccacgttaca actgactctg gtacaggtat tgtccataca gcccctggtt
    38221 ttggtgagga cgattacaat gttggtattg ctaataatct tgaagtcgca gtgactgttg
    38281 atgaacgtgg tatcatgatg aagaatgctg gtcctgaatt tgaaggtcaa ttctatgaaa
    38341 aggtagttcc aactgttatt gaaaaacttg gtaacctcct tcttgcccaa gaagaaatct
    38401 ctcactcata tccatttgac tggcgtacca agaaaccaat tatctggcgt gcagtaccac
    38461 agtggttcgc ctctgtttca aaattccgcc aagaaatctt ggatgctatt gataaagtta
    38521 aattccatac agaatggggt aaagtacgtc tatataatat gattcgtgac cgtggtgact
    38581 gggttatctc tcgtcaacgt gcttggggtg ttccacttcc aatcttctat gcagaagacg
    38641 gtacagctat catgacagct gagactatcg aatatgtggc tcaactcttt gaagtacatg
    38701 gttcaagcat ttggtgggaa cgtgatgcca aagacctctt gccagaagga tttacacatc
    38761 caggttctcc aaatggcgag ttcaaaaaag aaactgatat catggacgtt tggtttgact
    38821 caggttcatc atggaatggt gttttggtaa atcgtccaaa tctgacttat ccagctgacc
    38881 tttaccttga aggttctgac caataccgtg gttggttcaa ctcatcactc attacatctg
    38941 ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt acccttgacg
    39001 gtaaaggtga gaagatgtct aaatctcttg gaaataccat tgctccaagc gatgttgaaa
    39061 aacaatttgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca agcaatgacg
    39121 tgcgtatctc tatggatatc ttgagccaag tctctgaaac ttaccgtaag attcgtaata
    39181 ctcttcgttt cttgattgcc aatacatctg actttaaccc aactcaagat gcagtcgctt
    39241 acgatgaact tcgttcagtt gataagtaca tgaccattcg ctttaaccag cttgtcaaga
    39301 ccattcgtga tgcctatgca aactttgaat tcttgacaat ctacaaggcc ttggtgaact
    39361 ttatcaacgt tgatttatca gccttttacc ttgattttgc taaagatgtt gtttacatcg
    39421 aaggtgctaa atcactggaa cgtcgtcaaa tgcagactgt cttctatgat attcttgtca
    39481 aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatc tggtcatatc
    39541 ttgagtttga aacagaagac ttcgtccaat tgtcagaatt accagaagtt caaacttttg
    39601 ctaaccaaga agaaatcttg gatacatggg cagccttcat ggactttcgt ggacaagcac
    39661 aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg taaatcactt gaagcacact
    39721 tgacagttta tccaaatgaa gtggtgaaaa ctctactcga agcagtaaat agcaatgtgg
    39781 ctcaactttt gatcgtgtct gagttgacca tcgcagaagg accagctccg gaagctgccc
    39841 ttagcttcga agatgtagcc ttcacagttg aacgtgctgc tggtgaagta tgtgaccgtt
    39901 gccgtcgtat tgacccaaca acagcagaac gtagctacca ggcagttatc tgtgaccact
    39961 gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt gaagagaaat
    40021 aagattgaaa agtctaggca aaattcaatt tgagaagaaa agacaactaa ttttatagtc
    40081 tattaaacgc attgtatcac gtttttgaac acctgatatg atgcgttttt tatttatttt
    40141 aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa cttagcaagc
    40201 taacagtagt aagataaaat aggaatttga tattagggat aagattggta aatagtgtaa
    40261 tatttttaca agaataaat
//
LOCUS       DAVLHM010000019        39917 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLHM010000019 DAVLHM010000000
VERSION     DAVLHM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39917
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.019"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            343..1386
                     /locus_tag="VXE45_001015"
     CDS             343..1386
                     /locus_tag="VXE45_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0789061.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIIARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1553..3640
                     /gene="topA"
                     /locus_tag="VXE45_001016"
     CDS             1553..3640
                     /gene="topA"
                     /locus_tag="VXE45_001016"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0789062.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEENIK"
     gene            3746..4105
                     /locus_tag="VXE45_001017"
     CDS             3746..4105
                     /locus_tag="VXE45_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0789063.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4198..4830
                     /locus_tag="VXE45_001018"
     CDS             4198..4830
                     /locus_tag="VXE45_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0789064.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGVLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQVGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4874..5530
                     /locus_tag="VXE45_001019"
     CDS             4874..5530
                     /locus_tag="VXE45_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0789065.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     AADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5549..6169
                     /locus_tag="VXE45_001020"
                     /pseudo
     CDS             5549..6169
                     /locus_tag="VXE45_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            6197..6631
                     /locus_tag="VXE45_001021"
     CDS             6197..6631
                     /locus_tag="VXE45_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV0789066.1"
                     /translation="MVAGSMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6643..7680
                     /gene="leuB"
                     /locus_tag="VXE45_001022"
     CDS             6643..7680
                     /gene="leuB"
                     /locus_tag="VXE45_001022"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0789067.1"
                     /translation="MAKKIVALVGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLATIGSPQYDGAVVRPEQGLMTLRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSV
                     PDIAGQGIANPISMILSVSMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7677..7946
                     /locus_tag="VXE45_001023"
     CDS             7677..7946
                     /locus_tag="VXE45_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0789068.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            7950..8309
                     /gene="leuD"
                     /locus_tag="VXE45_001024"
     CDS             7950..8309
                     /gene="leuD"
                     /locus_tag="VXE45_001024"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0789069.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8528..8671
                     /locus_tag="VXE45_001025"
     CDS             8528..8671
                     /locus_tag="VXE45_001025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789070.1"
                     /translation="MTSDKAGLERKFAAKEGKRNKPGVVLCGSMDELCALAQLNPKIE
                     AFY"
     gene            8690..8944
                     /locus_tag="VXE45_001026"
     CDS             8690..8944
                     /locus_tag="VXE45_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789071.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            8934..9095
                     /locus_tag="VXE45_001027"
     CDS             8934..9095
                     /locus_tag="VXE45_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789072.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNL
                     WDYRQVEYY"
     gene            9258..9621
                     /locus_tag="VXE45_001028"
                     /pseudo
     CDS             9258..9621
                     /locus_tag="VXE45_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828316.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
     gene            9597..9911
                     /locus_tag="VXE45_001029"
     CDS             9597..9911
                     /locus_tag="VXE45_001029"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789073.1"
                     /translation="MDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAM
                     VTKLLCIYSEGDSFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVPKLILSWSH
                     RN"
     gene            9971..11188
                     /locus_tag="VXE45_001030"
     CDS             9971..11188
                     /locus_tag="VXE45_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0789074.1"
                     /translation="MDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTD
                     GNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGG
                     QDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYE
                     LYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEIS
                     KIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFD
                     FAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPS
                     YFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVA
                     DDNEGDENDDADY"
     gene            11175..12491
                     /locus_tag="VXE45_001031"
     CDS             11175..12491
                     /locus_tag="VXE45_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0789075.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12666..13652
                     /locus_tag="VXE45_001032"
     CDS             12666..13652
                     /locus_tag="VXE45_001032"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0789076.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13716..13787
                     /locus_tag="VXE45_001033"
     tRNA            13716..13787
                     /locus_tag="VXE45_001033"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13749..13751,aa:Arg,seq:ccg)
     gene            13970..14668
                     /locus_tag="VXE45_001034"
     CDS             13970..14668
                     /locus_tag="VXE45_001034"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0789077.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14659..18198
                     /gene="smc"
                     /locus_tag="VXE45_001035"
     CDS             14659..18198
                     /gene="smc"
                     /locus_tag="VXE45_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0789078.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLEIILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18195..18989
                     /locus_tag="VXE45_001036"
     CDS             18195..18989
                     /locus_tag="VXE45_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0789079.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            18989..19807
                     /locus_tag="VXE45_001037"
     CDS             18989..19807
                     /locus_tag="VXE45_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0789080.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLQAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19811..21100
                     /gene="ftsY"
                     /locus_tag="VXE45_001038"
     CDS             19811..21100
                     /gene="ftsY"
                     /locus_tag="VXE45_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0789081.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21146..22633)
                     /locus_tag="VXE45_001039"
     CDS             complement(21146..22633)
                     /locus_tag="VXE45_001039"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0789082.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(22782..23522)
                     /locus_tag="VXE45_001040"
     CDS             complement(22782..23522)
                     /locus_tag="VXE45_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0789083.1"
                     /translation="MVKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23522..25687)
                     /locus_tag="VXE45_001041"
     CDS             complement(23522..25687)
                     /locus_tag="VXE45_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0789084.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            25857..26810
                     /locus_tag="VXE45_001042"
     CDS             25857..26810
                     /locus_tag="VXE45_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0789085.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            26887..28875
                     /gene="uvrB"
                     /locus_tag="VXE45_001043"
     CDS             26887..28875
                     /gene="uvrB"
                     /locus_tag="VXE45_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0789086.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            28885..29448
                     /locus_tag="VXE45_001044"
     CDS             28885..29448
                     /locus_tag="VXE45_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789087.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29414..29902
                     /locus_tag="VXE45_001045"
     CDS             29414..29902
                     /locus_tag="VXE45_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789088.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            29976..30443
                     /locus_tag="VXE45_001046"
     CDS             29976..30443
                     /locus_tag="VXE45_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0789089.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30440..30955)
                     /locus_tag="VXE45_001047"
     CDS             complement(30440..30955)
                     /locus_tag="VXE45_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0789090.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(30967..31494)
                     /locus_tag="VXE45_001048"
     CDS             complement(30967..31494)
                     /locus_tag="VXE45_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0789091.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(31776..32339)
                     /locus_tag="VXE45_001049"
     CDS             complement(31776..32339)
                     /locus_tag="VXE45_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0789092.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32323..32874)
                     /gene="coaC"
                     /locus_tag="VXE45_001050"
     CDS             complement(32323..32874)
                     /gene="coaC"
                     /locus_tag="VXE45_001050"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0789093.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(32886..33575)
                     /gene="coaB"
                     /locus_tag="VXE45_001051"
     CDS             complement(32886..33575)
                     /gene="coaB"
                     /locus_tag="VXE45_001051"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0789094.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            33805..35475
                     /locus_tag="VXE45_001052"
     CDS             33805..35475
                     /locus_tag="VXE45_001052"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0789095.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            35803..36978
                     /gene="mutY"
                     /locus_tag="VXE45_001053"
     CDS             35803..36978
                     /gene="mutY"
                     /locus_tag="VXE45_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0789096.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            37033..37737
                     /locus_tag="VXE45_001054"
     CDS             37033..37737
                     /locus_tag="VXE45_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0789097.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            37730..39079
                     /gene="vicK"
                     /locus_tag="VXE45_001055"
     CDS             37730..39079
                     /gene="vicK"
                     /locus_tag="VXE45_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0789098.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            39081..39890
                     /locus_tag="VXE45_001056"
     CDS             39081..39890
                     /locus_tag="VXE45_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0789099.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT        12260 a         7097 c         8907 g        11653 t
ORIGIN      
        1 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
       61 tggttattat aaaaaatggt ctgaaataga tgatgatact tttcgaaaat ctttttacat
      121 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
      181 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catctgagtc aggatattat
      241 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
      301 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
      361 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
      421 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
      481 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
      541 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
      601 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
      661 gctagttcgg agattattgc tagaacctct ccgactattt gggatgttct cattgctttt
      721 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
      781 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
      841 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
      901 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
      961 gataatgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     1021 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     1081 aagaaattta tatcagagca gtttcagggg cataatattt tgaaaaaaac ctattctaaa
     1141 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     1201 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     1261 ttgtctgatt cagaacaact tagtaaggaa gaactggtgg agtatttctt ccagtatatc
     1321 aaggataagg aagcaaaaga aaaggaaaaa gctaataagt tttatacaga gtctgaggag
     1381 caataatttc ttgagaatag ctggtttttc tcgtgagtct tctatgtata tcaaaggaag
     1441 actgaggttt taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc
     1501 aaaaaatggt ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac
     1561 ggcaacaaaa aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc
     1621 taaggccaag acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg
     1681 gcatatccgt gatttgaaga aatccagtat gtccgttgat attgaaaata attatgaacc
     1741 gcaatatatc aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa
     1801 aaaagctaat aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg
     1861 gcatttggcc catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga
     1921 aatcaccaag gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt
     1981 ggtcgatgcc caacaagctc gtcggatctt ggatcgcttg gtagggtatt cgatttcgcc
     2041 tattttgtgg aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct
     2101 taaactcatc attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac
     2161 agttgatgct gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga
     2221 tggtaaaaag atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac
     2281 tagtaaagac ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt
     2341 accctatacc acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg
     2401 aaaaaccatg atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca
     2461 aggtttgatt acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga
     2521 ggcggcaagc ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt
     2581 caaaaacgca tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa
     2641 tacaccagaa agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat
     2701 ctggaatcgt tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa
     2761 attgtctcaa aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta
     2821 tcttgccatt tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga
     2881 tgtggtcaaa caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta
     2941 ttctgaagca acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta
     3001 cgcgccaacc attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt
     3061 tgaaccgaca gagttgggag aaattgtcaa taagctcatc gttgaatatt tcccagatat
     3121 cgtaaacgtg accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa
     3181 agagcagtgg cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa
     3241 ggctgaagaa gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga
     3301 agtgtgtggc agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag
     3361 caatttccca gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc
     3421 aagctgtcat cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tcttctatgg
     3481 ttgcaatcgc tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg
     3541 tccaaaatgt ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt
     3601 ttgtagcaaa ggcgactacg aggaagaaaa tattaaataa gaggaggggc ccgaaagtaa
     3661 atttcaggct ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag
     3721 aagattattt taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
     3781 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt
     3841 gttgtctatt gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac
     3901 caagctctat caaacatatg tagctgattt tcgcgagact aagtctatta cgcgtgaacg
     3961 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
     4021 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttatcacct attatctctt
     4081 caaggtcatt ccagacaaag aataattaaa acagtagtta tttcccttga taaaattgaa
     4141 agcatattca taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg
     4201 atttacgaat tttgtgctga aaatgtgacc ttgcttgaaa aagcgatgca ggctggagct
     4261 cgtcggattg aactctgtga taatctagca gttggtggga caacccccag ctatggagtg
     4321 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
     4381 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
     4441 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gagttttaac tgctgataaa
     4501 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
     4561 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
     4621 agtcaagtcg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
     4681 aaacgttttg ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta
     4741 ccaggtgggg ggattgacct tgacaaccgt caaaccttta tcgaccaggt gggggtaaca
     4801 cagttgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
     4861 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
     4921 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
     4981 tgactttgtc atgactgtgt ccatcgctgc tgataatgtg aactttcaag tctttgacca
     5041 agagactggc gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg
     5101 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
     5161 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
     5221 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
     5281 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
     5341 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tactttcaca
     5401 aaaggggatt tatccagcct ttcatatgag caagcgctac tggattagtg tgtcccttga
     5461 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
     5521 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
     5581 gaagaaattt tcagaaaata taggatttac cacactagag gaatatggtg catcttcaaa
     5641 tacctgattg agaatgtcaa gacggatcgt cagatcatct attcgcctca ctgtcatgat
     5701 gacctcggaa tggcagtggc aaatagcctt gctgctgtca agaatggtgc aggacgtgtt
     5761 gaagggacta tcaatggtat tagggagcga gctggaaatg ctgctttgga agaaattgca
     5821 gtggctctca atattcgcca agattactac caagtagaaa ccagtattgt cctaaatgag
     5881 accatcaata cgtcagaaat ggtttctcgc ttctctggta ttccagttcc taaaaacaaa
     5941 gccgtcgttg gtggcaatac cttctcccac gaatctggta ttcaccaaga tggagtcctt
     6001 aaaaatcctc tcacttatga gatcatcaca cctgaattgg ttggtgttaa gattccgctt
     6061 gggtcgccat gcttttgttg agaaactgag agaattggcc ctagatttta cagaagagga
     6121 tatcaaacca ctctttgcta agttcaaggc actggccgat aagaagtaag aaatcacaga
     6181 tgcagatatt cgagctttgg tagctggaag catggttgaa aatccagaag gcttccactt
     6241 tgatgattta caacttcaaa ctcatgcaga taatgacatt gaagcgctcg ttagcctagc
     6301 caatatggat ggtgagaaag tcgaatttaa tgcgacaggg caaggttccg ttgaagcaat
     6361 ctttaatgct atcgataagt tctttaacca atctgttcgt ttggtgtcct acactatcga
     6421 tgcggtaaca gatggaatcg atacccagga tcgggttttg gtcactgttg aaaacagaga
     6481 tacagaaacc atctttaatg cagcagggct tgattttgat gtgttgaagg cttctgctat
     6541 tgtctatata aacgctaata cctttgttca aaaagagaat gcaggtgaga tgggacgcag
     6601 tgtttcttac cacgatatgc ctagtgtgta aaggagaagg ctatggcaaa gaaaatagta
     6661 gctctagtag gagacggaat tggcccagaa atcatggagg ttggtttaga agttctggag
     6721 gctctagctg aaaaaacagg ttttgactat gagattgaca gacgaccgtt cggaggtgca
     6781 gatattgatg cagcatggcc tcccttacct gatgaaaccc ttaaggcaag tagggaagca
     6841 gatgctatcc tactagcaac tatcggtagt cctcagtatg atggagcagt ggttcgccct
     6901 gaacaaggcc tgatgactct ccgtaaggaa cttaatcttt acgctaatat tcgtcctgta
     6961 aaaatctttg acagtctcaa gcatttgtca ccactcaaac tggaacgaat tgctggtgta
     7021 gactttgtcg tggtgcgtga attgacaggc gggatttact ttggagatca tattcttgaa
     7081 gagcgcaatg cgcgtgatat caacgactat agctatgagg aagtggagcg gattattcgc
     7141 aaagcctttg aaattgcaag aaatcgcaga aaaatcctta ctagtatcga taagcaaaat
     7201 gttctagcga cctcaaaact ctggcggaaa gtagctgagg aagtcgcaca ggatttctca
     7261 gatgtaacct tggaacacca gctggtagac tcagctgcta tgcttatgat taccaatcct
     7321 gctaagtttg atgttattgt aacggagaat ctttttggag atattttatc tgatgaatca
     7381 agcgtcttat ctggtacact tggggttatg ccatcagcca gtcattctga aaatggacca
     7441 agtctctatg aacctattca cggttcagta cctgatattg caggtcaagg aattgccaat
     7501 cctatttcca tgattttatc agtttccatg atgttaagag atagtttcgg aggttatgag
     7561 gatgcagagc gtatcaaacg tgctgttgag acaagtttgg cggcaggaat tttaacgaga
     7621 gatataggag gtcaggcttc aacaaaggaa atgacggaag ctattattgc aaggttatga
     7681 agttagacga aaaaattact ctagtccttt tgatttggaa tgtcatcatt ttcttgattt
     7741 atggcattga caaattcaag gcaagaagaa gagcttggcg catcccagag aaaatcttac
     7801 tcattttagc ccttacttgt ggtggttttg gggcctggtt agctggaatc acttttcacc
     7861 acaagactcg aaaatggtac tttaaaacag tttggtttct tgggatggtg accacactag
     7921 tagccttata ttttatttgg aggtaatgga tggcagggtc ttcgagggaa cacgctgctt
     7981 gggctctagc ggactatggt tttaaggtcg tgattgcagg atctttcggt gacattcatt
     8041 acaataatga actcaataat ggcatgttgc caatcgttca gcctagagag gttagagaga
     8101 aactagccca gctaaaacca accgaccagg taactgtgga cttggaacaa caaaaaatca
     8161 tctcaccagt tgaagaattc accttcgaga tagatagcga gtggaaacat aaactcctaa
     8221 atagtttgga tgatatcggt attaccttgc agtatgaaga gttgattgct gcttatgaaa
     8281 aacaacgacc agcctactgg caggattaga aaaaatagaa aaggaaatat agtaaactga
     8341 aataagatgt aaacaaatga attggagctt aacatccatt tccagcaatt ttttagaaac
     8401 tacagtggac tattctggat tcaacacatt ataaaattat gacaaaacac attcacaaga
     8461 aggctacgac attttaaaag gtgagggcgg atgtatcgtt tgccctacta aagttggtta
     8521 cattatcatg accagcgaca aggcaggact tgagcgtaag tttgcagcca aagaaggtaa
     8581 gcgtaacaaa ccaggtgttg ttctctgcgg tagcatggat gaactttgcg ctttagcgca
     8641 actcaaccca aaaattgaag cattctacta aaaacattgg gatgaagata ttcttcttgg
     8701 ttgtatcctt ccttggaaac cagaagcctt tgaaaaactc aaagcatacg gggatggccg
     8761 tgaagaactt atgactgatg tacgtggtac tagctgtttt gttatcaagt ttggaaaagc
     8821 aggtgaacaa ttggctgcca agctttggga agaaggtaaa atggtctacg cctcatatgc
     8881 ttcaatgaca aaacgattga aactcgctat gagagcaagg tgtaatggtg tctatggtcg
     8941 ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacctca ccagcaccag
     9001 ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca gacaccttta
     9061 acttatggga ctaccgtcag gttgagtatt attaggatag agaagaagtc tagtgttaag
     9121 gacattacag ctcataatac taggcttttt tatagaaatt cttttctttt tctataggat
     9181 atggtattct atgtagaaaa tatatgttaa taagtaatgc caatatttaa acatcattag
     9241 taaaaggagt tagattgatg aataaaagaa aagttagttt agaagatttt tataaatggt
     9301 atagtctaaa taaagaagag ttattaaata aggcaactgt tggtgaaaag tttaatgata
     9361 aattaaaaga agagtttctc caggaatggc ctttggatag gattttaaca atgtcaatcg
     9421 atgaatatgt aataggaaag ggacagcaaa ataagtcttt atgctacgct cttgagaagg
     9481 gaaaatacaa aaatctattt cttggaattt ctggtggctc agcttcaaaa tttggtattt
     9541 attggaataa aaaaacaaac aaatataaag atcaagctaa taatgagatt tcagagttgg
     9601 atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat tatcaaagaa ggtattcgtt
     9661 ttaactttga aaatcctatt tttgatatga aaagatcaac aaatgaattt attggtcgtt
     9721 ctgctatggt gacaaaatta ctttgtatct attctgaggg agattctttc tttggtgtaa
     9781 atattaatag tcagaaagaa ttttggaacc actttgtttc tcagacaaat caaggtggac
     9841 cttatctgca aaatcataaa ataattgaac tggtgccaaa acttatcctg agttggagcc
     9901 atcgaaatta ggaactatgc tttttgagta ttctaagctt tttatggaaa ataaggaaga
     9961 caatagtaca atggattcat caaacaattt tcgtcatcaa ttaactcaat ctctattaaa
    10021 gtctccaaac cttatccttc gtggtgctcc tggcacagga aagacttatc ttgctaaaga
    10081 aattgccaaa gaattaacgg atggcaacga agaccaaatc ggatttgtac aatttcaccc
    10141 atcatatgat tatacggatt ttgtagaagg tttaagacca gtatcaaatg gggatggagc
    10201 tattgagttt aggctacagg acggtatttt taaagatttt tgtcagaaag caaaagaaac
    10261 ccaattgatt ggaggacaag ataattttga tgaggcttgg gattcttact tagaatatat
    10321 aaatgttgct gaagaaaaag aatatataac aaaaacatct tacttatctg ttaatagtag
    10381 acaaaatttg tcagtaaatt atgatagtgg tgttccagga tggtcactac ctagcaaata
    10441 tgtttacgag ttgtataaag ataaaaatta taataagcaa gaatactaca aaagtggtgg
    10501 aaaaactgtc ctagaaacat tgagaaagag atttggtttg aaagactatg tttccccaac
    10561 agaaattgat actgataaga aattcgtctt catcatcgat gaaatcaatc gtggggagat
    10621 ttctaagatt tttggcgaac tctttttctc tatcgaccct ggctatcgtg gtgaaaaagg
    10681 aagtgtttct acccaatatg caaatctaca cgaaactgat gaaaagttct atatccccga
    10741 aaatgtttac atcatcggaa ctatgaatga tattgatcgt tcagtggata cctttgattt
    10801 tgctatgcgt cgtcgttttc gttttgttga agttactgcc gagggtcaag ttggcatgtt
    10861 ggataaagag ctgaatatcc atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc
    10921 tgctatcgaa aatgttcagg aattaaacag tcattatcat attggaccaa gttattttct
    10981 taagttgaag gatgtagatt ttgactatga attactctgg tccgattata ttaagcctct
    11041 cctagaagac tacttgcgag gttcttatga tgaggttgaa actttggaaa ctttgaaaaa
    11101 agcatttgaa ctgacaaata atgagcaaaa agatcaggca gtagctgatg acaatgaagg
    11161 tgatgaaaac gatgatgcgg attactgata atcaacacaa gattattaaa gaaaaatttg
    11221 ttgaagaata tcctaaacta agcaatcttc ttttagacag aaccttggaa agtctatccc
    11281 aagatgaacg tattttcatt tttccaaatg atttgactca tactcctgat ttggataagg
    11341 accaaaagat ttttgaaaca gtcaatcaga aaatcaagac agggaacgtg attggttttc
    11401 ttggatatgg tcaggaaaga ttaacgattt cctcacgatt ttctgatgag agtaatgacc
    11461 attttttgca ttatctctta aacaaggttc ttcatatcaa tctcactagt ttagatgttg
    11521 ctttgtctcg tgaagagagg ctttatcaac ttttggtgta tctctttccc aagtatctac
    11581 aagctgctat tcgaaaaggt ctttataagg aatatcatcg attttctcat aacgacagta
    11641 atgttaaggg agtgattgat gtaagaagcc atctcaagaa aaatcttcct ttcacgggaa
    11701 atattgccta cgcaacgaga gagttcacct atgataatcc cctcatgcag ttggtccgtc
    11761 acactattga atacattaag aatcagaaaa gcattggtca aggggtacta gataatctct
    11821 caactagtcg tgaaaacgta tctgaaatcg tgcgtgtaac gccctcttat aaactagctg
    11881 atcgtgctaa gattattcgg ggaaatcaat ctaaacctat acgtcatgca tactttcacg
    11941 agtacagaaa cttacaagaa ctttgtctga tgatcctaaa ccaagaaaag cacggtttag
    12001 ggtatcaaga tcaaaaaatc tatggtattc tctttgatgt tgcctggctt tgggaagagt
    12061 atgtttacac cttgttgcca aaaggttttg tacatcccag aaataaggat aagacggatg
    12121 gaatttcagt attttctgtt gggaaacgaa aagtatatcc agatttttat gacagagaac
    12181 gaaagattgt tctagatgca aaatataaaa aactggaatt gactgaaaaa ggaatcaacc
    12241 gtgaggactt attccagctg atttcctatt cttatatttt aaaagctgag aaggctggac
    12301 tgatttttcc tagtatggag cagtcagtaa atagtgaaat aggaaaagta gctggctatg
    12361 gagctcaatt gaagaagtgg tctattcgaa tccctcagaa tgcctcattc tatagtacat
    12421 tttgtaaaat gatggaaaat tcagaagaaa attttaaagc gattattgat gaagaagtgg
    12481 ggagaaaata atttcccctc tttcttttat ttttaacaca agtaaaaccc gaacgatata
    12541 ttttaattca taaaataatt tgacaaaaac tgtactttgg tttataataa attaaggaaa
    12601 cgtcggaaaa ggcgtagtga tgcaagagca taggtaggtc attacaaaag aaacgagaca
    12661 tcgatatgtt aaatgaattt ccaatttttg attacgaaga tattcaattg attccaaata
    12721 aatgtgtcat taaaagccgt gcagaagcgg atacaagtgt cactttagga aatcacacct
    12781 ttaaactacc tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat gtagcagagc
    12841 aactggctaa aggtggttac ttctacatta tgcaccgttt tgatgaggca ggacgcattc
    12901 cttttattaa acgaatgcac gatcaagggc tcattgcttc tatctctgtc ggtgttaagg
    12961 attatgagta tgatttcgtt agacagctca aggctgatgc tcctgagtat atcactattg
    13021 atattgctca tggtcatgcg gatagcgtga tttctatgat tcaacacatc aagaaagaat
    13081 tgccagatac ctttgtcatt gctggaaatg tgggaacacc agaagctgtg cgtgaattgg
    13141 aaaatgctgg tgcggatgct actaaggtcg gaatcggtcc tggtaaggtt tgtatcacca
    13201 aggttaagac tggttttggt acaggtggtt ggcagttggc tgctctacgc tggtgtgcca
    13261 aggctgcgcg taaaccgatt atcgctgatg gaggaattcg tactcacggt gatattgcta
    13321 agtctatccg cttcggtgct agcatgatca tgattggttc cctctttgca ggacacattg
    13381 aaagtccagg gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat tatggttcag
    13441 cctcacaata tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc ttgcttcctg
    13501 ctaaaggtca tctgcaagac actttaactg agatggaaca agaccttcaa agtgctattt
    13561 cttatgcagg tggacgtcag gttgctgacc ttaaacacgt tgattatgtg atcgtgaaaa
    13621 actccatctg gaatggggat gcttcccact aagacggggt ctttgaccaa aaaacttgtt
    13681 attagagcaa atttctgtta taataaaaca agtttccacc cttagtgtaa tggatatcac
    13741 gtaagattcc ggttcttgag atgggggttc gattccctca gggtggatgt aaacatccta
    13801 aaaagccttt aatagggctt ttttctttat cctgacccaa atttgccgct aaaactgaga
    13861 atctctgtct aaagaattcc caaatgcttt ccagtcccgt tttagagtga ctcagggggc
    13921 tttttttgat ataataaaaa ggactattat cagttagaaa gaggttggta tgaaagaatt
    13981 acaaactgta ctaaagaatc attttgcaat cgaatttgca gacaaaaatt tactggaaac
    14041 tgcctttact catacgagtt atgccaatga gcaccgcctc ttaaaaattt cacacaatga
    14101 acgcttggaa tttttaggag acgctgttct acagttattg atttcagaat atctatataa
    14161 aaaatatcct aaaaagcctg aaggtgacct atcaaaactc cgtgctatga ttgtccgtga
    14221 ggagagttta gctggttttg cgcgtgattg ccagtttaac cagtttatca agttgggtaa
    14281 aggggaagaa aaatcaggtg gtcgcaatcg tgacaccatt cttggtgatg cctttgaagc
    14341 ctttcttggt gcccttcttt tggataagga tgtggccaag gtcaaggaat ttatctatca
    14401 agtcatcatt cctaaggttg aagcaggcga gtttgagatg attacagact ataaaaccca
    14461 tctccaagag ttgcttcagg tcaatggtga tgtggctatt cgttatcagg tgatttctga
    14521 aacagggcct gctcatgata aggtctttga tgtagaagtt cttgttgaag gtaagagcat
    14581 cggtcaaggc caaggtcgtt ctaagaaatt agcagagcag gaagctgcca aaaatgccgt
    14641 tgagaagggg ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt caagtctttt
    14701 gctgataaga ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg acccaatgga
    14761 tctggaaagt ccaatattac agaaagtctg cgttgggctt tgggggagtc tagtgtcaag
    14821 agtctccgtg ggggcaagat gccggatgtc atctttgctg gaaccgaaag tcgcaaaccg
    14881 ctcaattatg cttctgtagt tgtgactctg gataatcatg acggatttat caaggatgca
    14941 ggtcaagaaa tcagggtgga acgccatatc tatcgtagtg gagatagcga atacaagatt
    15001 gacggcaaga aagtccgtct gcgtgatatt catgacctct tcttggatac tggattggga
    15061 cgagattcct tctctattat ttcccaaggg aaggttgagg agatttttaa ttccaagcct
    15121 gaggaacgac gagctatttt tgaagaagct gctggagttt taaaatacaa gactcgcaga
    15181 aaagaaaccg agagtaaact gcagcaaact caggataatc tggaccgctt agaggacatt
    15241 atctacgagt tggataatca aatcaagcct cttgaaaagc aagctgagaa tgcccgtaag
    15301 tttttagact tggaaggaca acgtaaggct atttatttag atgttctggt tgctcaaatc
    15361 aaggaaaata aggctgaact agagtcgaca gaagaagagt tggctcaggt tcaagaactc
    15421 ttgatgagtt attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac tcttaaaaag
    15481 caacgccaag atttacaggc tgaaatggcc aaagaccaag gcagtttgat ggatttgacc
    15541 agtctgatta gtgacttaga gagaaaatta gccctatcga aactggaatc tgagcaagta
    15601 gccctcaatc aacaggaagc acaagcccgt ttggctactt tggaggataa gagaagttca
    15661 ctcagccaag aaaaatctga taaagaaagc tctttagccc tcttggaaga aaatctagtc
    15721 caaaataatc aaaaactcaa tcgattagag gctgaattgc tagctttttc agatgatcct
    15781 gatcagatga ttgagctctt acgtgaacgc tttgtggccc ttttacaaga agaagcagat
    15841 gtctcaaacc aactgacccg tattgagaat gagttggaaa atagtcgtca gctttctcaa
    15901 aaacaagcag atcaactaga aaagctgaaa gaacagttgg ctacagctaa agagaaggct
    15961 ggtcagcaaa aggctgagct tgaaactgcc aaggagcagg ttcagaaatt attggccgac
    16021 tatcaagtct gtgctaagga gcaagaggag cagaaaactt cctatcaagc tcaacaaagt
    16081 caactctttg accgtctgga tagtctcaaa aacaagcagg ctagagcgca aagtttggaa
    16141 attatcctga gaaatcatag taacttttat gcaggtgtta agagtgttct ccaagagaaa
    16201 gatcgtctag gtgggattat tggagcagtt agtgagcacc tgacctttga tgtgcattat
    16261 caaactgccc tagagattgc gcttggagcg agtagccaac atatcatcgt ggaagatgaa
    16321 gagtcggcaa ccaaggcgat tgatttactc aaacgaaaca gatctggtcg tgcaaccttc
    16381 cttcctttga ccactatcaa ggctcgtacg atttctagtc agaaccaaga tactattgct
    16441 gcaagtccag gatttctggg catggcagat gagctggtta ctttcgatac tagactggaa
    16501 gccattttca agaatttgct agctacaacg gccatttttg ataccgtgga gcatgcgcgt
    16561 gcagcagcgc gccaggttcg ttatcaggtt cgtatggtga cattggacgg aacagagctg
    16621 cgcacaggtg gttcttatgc aggtggagct aatcgccaga ataacagtat tttcatcaag
    16681 ccagaactgg agcaattaca aaaagaaatt gctgaagaag aagcaagttt gcgttcagat
    16741 gaagtgagtt tgaagaactt gcaagatgag ctagctagat tgacagaaag attagaagcc
    16801 atcaaatctc agggagagca ggctcgtatt caggagcaag gcttgtccct cgcctatcag
    16861 cagaccagtc agcaagttga agagctagaa actctttgga aactccaaga agaggaatta
    16921 aatcgtcttt ctgagggaga atggcaagcg gataaggaaa aatgccaaga gcgccttact
    16981 acaatcacta gtgaaaagaa taatctggaa gctgagattg aagagattaa gtctaataaa
    17041 aacgccatcc aagaacgtta tcaaaacttg caggaagagc tagctcaagc tcgtctactt
    17101 aagacagaac tgcaagggca aaaacgttat gaagttgctg atattgaacg cttaggtaag
    17161 gaactagata atcttgatat tgagcaagaa gaaattcagc gccttcttca agaaaaggtt
    17221 gacaatcttg agaaagttga tacggatttg ctcagtcaac aggctgatga agccaaaact
    17281 caaaaaacaa atctccaaca aggtttgatt cgcaagcagt ttgagttgga tgatattgag
    17341 ggtcaactgg atgatattgc tagtcatttg gatcaggctc gccagcagaa tgaagagtgg
    17401 attcgcaagc aaactcgtgc tgaagccaag aaagaaaagg ttagcgagcg cttgcgccat
    17461 ctacaaagtc aattaacaga ccagtaccag atcagctaca cagaagcttt agaaaaggcg
    17521 catgagttgg aaaatctcaa tctggcagag caagaagtta aggatttaga gaaggctata
    17581 cgctcactgg gtcctgtcaa tttagacgct attgaacagt acgaagaagt tcacaaccgt
    17641 ctggatttcc taaatagcca acgtgatgat attttgtctg cgaaaaacct gctccttgag
    17701 accattacag agatgaatga tgaggtcaag gaacgcttta aatcaacctt tgaggtcatt
    17761 cgtgagtcct ttaaagtgac cttcaagcag atgtttggtg gaggtcaggc tgacctcatt
    17821 ttgactgaag gagacttgct gacagctggg gttgaaattt ctgtccaacc accaggcaag
    17881 aaaatccagt ctcttaatct catgagtggt ggtgaaaaag ccctatcggc tcttgccttg
    17941 ctcttctcca ttattcgtgt caagactatt ccatttgtta tcttggatga ggtggaagct
    18001 gcgctggatg aagccaatgt taaacgtttt ggggattacc tcaaccgctt tgacaaggac
    18061 agccagttca tcgtcgtaac ccaccgtaag ggaaccatgg cagcggctga ttccatctat
    18121 ggagtgacca tgcaagaatc gggtgtttca aagattgttt cagttaagtt aaaagattta
    18181 gaaagtattg aaggatgaca attaaactag tagcaacgga tatggacgga accttcctag
    18241 atgggaatgg acgctttgat atggatcgtc tcaagtctct cttggtttcc tacaaggaaa
    18301 aagggattta ctttgcggta gcttcgggtc ggggatttct gtctctagaa aaattatttg
    18361 ctggtgttcg tgatgacatt attttcatcg cggaaaatgg cagtttggta gagtatcaag
    18421 gtcaggactt gtatgaagcg actatgtctc gtgactttta tctggcaact tttgaaaagc
    18481 tgaaaacttc accttatgta gatatcaata aactgctctt gacgggtaag aagggttcat
    18541 atgttctaga tacggttgat gagacctatt tgaaagtgag tcagcactat aatgaaaata
    18601 tccaaaaagt agcgagtttg gaagatatca cagatgacat tttcaaattt acaaccaact
    18661 tcacagaaga aacgctggaa gatggggagg cttgggtaaa cgaaaacgtt cctggtgtta
    18721 aggccatgac aactggcttt gaatccattg atattgttct ggactatgtc gataagggag
    18781 tggccattgt tgaattagtt aaaaaacttg gtatcacaat ggatcaggtc atggcttttg
    18841 gagacaatct taatgactta catatgatgc aggttgtggg acatcctgta gctcctgaaa
    18901 atgcacgacc tgaaatttta gaattagcaa agactgtgat tggtcaccat aaggaacggt
    18961 cggttatagc ttatatggag ggcttataat ggcagatata aaattgattg cattggactt
    19021 ggacgggacc ttgctgacta ctgataaaag gctgacggat cgtaccaagg aaaccttgca
    19081 agctgcgcgt gatcgtggta tcaaggtcgt attgacaact ggtcgtccct taaaagccat
    19141 ggatttcttt ctccatgagt tagggactga cggtcaggaa gatgagtata ccattacttt
    19201 taatggtgga ttagttcaga aaaatacagg agaaatcctt gataaaacag tcttttcata
    19261 tgatgatgtg gcacgtttgt atgaagaaac agagaaatta tcactgcctc ttgatgccat
    19321 ctcagaagga acagtttatc aaatccaatc ggaccaagaa agtctttatg ccaaattcaa
    19381 tccagctttg acctttgttc cagtggactt tgaagactta tctagtcaaa tgacctacaa
    19441 caaatgcgtg actgcctttg ctcaagaacc cttggatgca gccattcaga agatttctcc
    19501 agaattgttt gaccaatatg aaatctttaa atcacgtgaa atgttgctag aatggtcacc
    19561 aaagaatgtt cataaagcaa caggtttggc aaaactaatc agccatcttg gaatcgacca
    19621 aagtcaagtg atggcttgtg gtgacgaggc caatgacctc tctatgattg aatgggcagg
    19681 tcttggtgtt gctatgcaaa acgctgttcc tgaagtaaag gcagccgcaa atgtagtgac
    19741 gccgatgacc aacgatgagg aagctgtcgc ctgggctatc gaagaatatg tgctaaagga
    19801 gaactaagat atgggattgt ttgaccgtct attcggaaaa aaagaagaac ctaaaatcga
    19861 agaagttgta aaagaagctc tggaaaatct tgatttgtct gaagatgttg atcctacctt
    19921 cacagaagtt gaggaagttt ctcaggaaga agcagaggtt gaaattgttg aacaagctgt
    19981 gttccaagaa gaggaaatcc aagacacagt tgaagaaagt caggattcag agccagctgt
    20041 aggggtttct caagaagaaa tagaagaatt accaaactca gaagaattac cagaggaaga
    20101 gaagcttgag cacgaaggaa ctgtagaaga aaataattct gaagtgcttg aaccagaagc
    20161 tcctcaaaca gaagaaactg ttcaggaaaa atatgaccgc agtcttaaga aaactcgcac
    20221 aggtttcggt gcccgcttga atgccttctt tgctaacttc cgctctgttg acgaagaatt
    20281 tttcgaggaa ctggaagaac tgctgattat gagtgatgtt ggtgtccaag tcgcttctaa
    20341 cttaacggag gaactacgtt acgaagccaa gcttgaaaat gccaagaaac ctgatgtact
    20401 tcgtcgtgtc atcattgaga aattggttga gctttatgaa aaggatggta gctacgatga
    20461 aagcatccac ttccaagata acttgacagt tatgctcttt gttggtgtga atggtgttgg
    20521 gaaaacaact tctatcggaa aactagccca ccgctacaaa caagctggta agaaggtcat
    20581 gctggttgca gcagatacct tccgtgcggg tgcagtagct cagctagctg aatggggccg
    20641 acgagtagat gttccagtag taactggacc tgaaaaagct gatccagcca gcgtggtctt
    20701 tgatggtatg gaacgtgccg tgactgaagg tatcgatatt ctcatgattg atactgctgg
    20761 tcgtctgcaa aataaggata accttatggc tgagttggaa aagattggtc gtattatcaa
    20821 acgtgttgtg ccagaagcac cacatgaaac cttcttggca cttgatgcat caacaggtca
    20881 aaatgcccta gtacaggcca aagaattttc gaaaatcaca cctttaacgg gaattgtttt
    20941 gactaagatt gatggaactg ctcgaggagg tgtggttcta gccattcgtg aagaactcaa
    21001 tattcctgta aaattgattg gttttggtga aaaaatcgat gatattggag agtttaactc
    21061 agaaaacttt atgaaaggtc tcttggaagg tttaatctaa tcagaagcaa aaatcctgca
    21121 aggcataaac ttgcaggaaa tttttttatt ctaagcgacc atcttgacga taggtgatat
    21181 ctggttgcca agtccatttg gcaccgaatt tttcaagtag gtcaaagctg gcttgaggtc
    21241 ccatgcttcc agctttatag tcatgaagtg gggcaccatt ttcagcccag agcttttcaa
    21301 tacggtcaat caacttccat gacgcacaaa cttcatccca gtggctaaag ttagttgagt
    21361 tgttatttag gacatcataa atcaattttt cgtatggttc tggagaagca ccagttgcag
    21421 tcgcatctgt acggtaatca agtgagttag gagccaagtt aaattcttct cctacttgct
    21481 tcccatttag gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg
    21541 gagcaagtgg ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgggttc
    21601 ctttttcagt cagtcgttta cctgtacgga aaaagaaagg aacaccacgg aatcgatcgc
    21661 tgtctacaaa gaaggcacca gatgtaaagg tttcagttgt tgattctgga ttcacatttg
    21721 gctcgctacg ataagagatg tatttcatgc catcaatctt accagagcgg tattgcccac
    21781 ggataaagtg ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa
    21841 tcttttcagc acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgaggagcg
    21901 aaagaagttg tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt
    21961 agccaccacg ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa
    22021 aatccttgtt ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt
    22081 ggatcatttc cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg
    22141 ctaggagttc gtcattcaac ttgcttgcag ttgcgtaatc tgtaccaaat ggtttttcaa
    22201 cgatcaagcg ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa
    22261 tggttccaaa gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt
    22321 atttttcatt aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga
    22381 catcatggct ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg
    22441 ccaaatcaag gatggactcg acaactacag attcaaaata ttccttactc caaggtctac
    22501 gggcagttcc aataacggca aagtgcttgg aaagattgcc ggattgatat agtctaaaaa
    22561 gggaagggta gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa
    22621 ccttagatga catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag
    22681 gaaacctcat ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat
    22741 acgaggtaga aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta
    22801 tctaagaact ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg
    22861 tcttcaagga actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat
    22921 cccatctcat gggttacgat aatcatggtc atgccttgct cagccaattc cttcataacg
    22981 ttaagtacgt ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg
    23041 atgtctggat tcattgctag gccacgagcg atggccacac gttgtttttg accacctgat
    23101 aggctatctg gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt
    23161 cccaattcct cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg
    23221 ttgtccaata cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt
    23281 tcacggacgt ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg
    23341 tgaccgctag tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa
    23401 cctgaaggac cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt
    23461 aggacttcat tttttccata gtgcttgtgt aaatcattta catcaatttt taattttacc
    23521 attaacgaat cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa
    23581 gatagaagat agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa
    23641 tcttaccagt ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa
    23701 gagcgataac gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga
    23761 taatcttacg catggttttt ccataagaga tacccaagct tcggctggct tccatttggc
    23821 caactggaac ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga
    23881 gtgagagggc aatggttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag
    23941 actcgatgaa gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac
    24001 cacgaataac gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc
    24061 taaacatacc gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag
    24121 caagagtgat accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga
    24181 gcgttgtttc gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt
    24241 caagaatctt ttggaattca ccgtttgctt taaggtttgc aagtccgttg ttgaacattt
    24301 caatcagttc tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc
    24361 cagagattgg agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat
    24421 catccataac ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag
    24481 caaaggtttt gattttgtag ccgtatttgc tttgattttc tgttaggaag gtttgagaag
    24541 cagttccgtt tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattgc
    24601 ttgattcttt gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag
    24661 ttgccttacg agcatctgtg acagacatac cagcgatgat accatcggct tgaccagctt
    24721 ggacagcact gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt
    24781 ctttagcgat tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt
    24841 ggaaaacaaa aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa
    24901 tagcttttaa tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc
    24961 atttcttgat aattttatca agactaccat cttttttcat ttcagacaag gcttggttaa
    25021 attcagtaac caggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta
    25081 cagcttcacc atccatttca atatggaggt cttgaccttg gttaatggca tattcgataa
    25141 caggtttgtc atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat
    25201 caccagtgtc aaatgtttta atagtaaagc cgtatttatc tttgattgtt tcaaggaaac
    25261 gttgagcggc agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc
    25321 taattttgtg tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca
    25381 tggtgaagac tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt
    25441 gcccagcttg aaccgcattg actgctgcgt caaatccagg ataggacatc tgaatgttcc
    25501 agcctttaat ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat
    25561 ctgaatcttt aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg
    25621 ctttggcaat acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt
    25681 tcttcatttt tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa
    25741 ggcaaatttt tatatttttc gtgtcagaaa atataacatc gattttttcc tttccttgaa
    25801 ttgctattaa aaagtgctat aataatagta tatatagaag aaaagaggac ggggatatga
    25861 agaacaaaag aatatttaaa gacttccaag cttcaaaaat gagtttaaac atttacacaa
    25921 gccccttgtt agcctttgtt tttgtcttca taggagagtt tgtggctttt actttgtatg
    25981 gtattggctt gttagctctc atcggacttg ctagaaattt tggagaggct ggtcaaaatc
    26041 ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga taaaacaagt gactttcgtt
    26101 taattttagg attactggcc tttggtttta ttcttaacac tgtgttcaga tggacaagaa
    26161 aagttgagaa aagacctatt cgaaccttgg gattttatag agagaatttc ctcagcaatc
    26221 ttctgaaagg atttagtcta ggcctggcac tttttcttct gaccttgtta ggtttagtgg
    26281 tcttaggtca atatcgtttg gaatccattc acttgaatcc ttattctctt gcctttgtcg
    26341 tctttactat cccattttgg attttacagg ggacagcaga agaagtggtg gcccgtgctt
    26401 ggctacttcc tcaattggcc tcaagaacca atctaaaact agctattctt atatctagcc
    26461 tgttctttac cctgcttcat atgggcaatt ctggtctcac ccctctatct ctagtaaatc
    26521 tctttttatt cggagttgcc atggctcttt accttctcaa aactgataca gtttggggtg
    26581 ttgcaggtat tcatggtgct tggaattttg ctcagggtaa tctctttggg attttagtta
    26641 gtggtcaacc gtcaggaacg tctctgatga cctttttacc acaaggcaat caagattggc
    26701 tatcaggtgg ttcttttggc atagaaggtt ccattatgac aagtctggta ttactactgc
    26761 tgattgtcta tcttgctaat aaattaaaga aagaaaatga aaggatgtga cttcggtccg
    26821 tccttttctt cgtgaaaata ctataagtat gctaaaatag gaatagcaca tggagagagg
    26881 attcttatga tcaatcacat tacagataat caatttaaac tagtatcaaa atatcaacca
    26941 tcaggagatc aaccccaagc tatcgagcag ttggtggata acattgaggg gggagaaaaa
    27001 gctcagattc tgatgggggc gactggaaca gggaagacct atactatgag tcaggtcatt
    27061 tctaaagtca ataaaccaac tctggttatt gcccacaata aaactctggc tggtcagctc
    27121 tatggggagt ttaaggaatt tttccctgaa aatgcagttg agtatttcgt atcctactat
    27181 gattattacc agccagaggc ctatgtccct tctagcgata cctatattga gaaggatagt
    27241 tctgtcaatg acgagattga caagcttcgc cactcagcta cctcagccct tttggagcgt
    27301 aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg gtttgggttc gcccaaggaa
    27361 tacgctgata gtgtcgttag tctccgtcct ggtctagaga tttctcgtga taaactcttg
    27421 aatgacttgg tcgatattca gtttgaacgt aatgatattg atttccaacg cggaagattt
    27481 cgcgttcgtg gggatgtggt agagattttc ccagcttccc gagatgaaca tgcctttcga
    27541 gtagaatttt ttggagacga aattgaccgt attcgtgaag ttgaggctct gacaggtcag
    27601 gtgttgggag aagtggatca tttagcgatt ttcccagcga cacactttgt gaccaatgac
    27661 gaccacatgg aagttgccat tgcaaagatt caggccgagt tggaagaaca attagctgtc
    27721 tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga aacagcggac agagtatgat
    27781 atcgaaatgt tgcgtgagat gggctatacc aatggggttg aaaattattc tcgccacatg
    27841 gatggacgga gcgaaggaga gcctccttat acgcttctcg acttcttccc agatgatttc
    27901 ttgattatga ttgacgagag tcatatgacc atagggcaaa tcaagggcat gtacaatgga
    27961 gaccgttcgc gtaaagaaat gctggttaat tatggtttcc gtttgccgtc tgctttggac
    28021 aatcgtcctc tccgtcggga ggagtttgag agtcacgttc atcagattgt ttacgtttca
    28081 gcgacacctg gtgactatga aaatgaacag accgagacag tgattgagca aatcattcgt
    28141 ccaacgggac tcttggatcc agaggtggaa gtccgtccga ctatgggaca gattgatgac
    28201 ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc gtacctttat cacaactttg
    28261 accaagaaaa tggcagagga tttgaccgac tacttcaagg aaatgggtat caaggtcaag
    28321 tacatgcact cggatatcaa gaccttggaa cggacggaga ttatccgtga cctgcgcttg
    28381 ggtgtctttg atgtcttggt cggaattaac ctgctccgtg aaggaattga cgttcctgaa
    28441 gtgagcctcg tagctattct cgatgctgac aaggaaggtt tccttcgcaa cgaacgtgga
    28501 ctcatccaga ctattggacg tgctgctcgt aacagtgaag gccatgtcat catgtatgca
    28561 gacacggtta cccagtctat gcaacgtgct atcgatgaaa ctgcccgccg tcggaaaatt
    28621 cagatggcct ataatgaaga gcatggtatc gtaccacaga caatcaagaa agaaatccgt
    28681 gacctgattg ccgtgaccaa ggcagttgct aaggaagagg acaaggaagt cgacatcaat
    28741 agcctcaaca aacaagagcg caaagaactc gtcaagaaac tagaaaaaca aatgcaagaa
    28801 gccgtcgaag tgcttgactt tgaactggcg gctcagatcc gtgatatgat gttggaagtc
    28861 aaggccttgg attaggggaa tagtatgatt tatttaagaa agttaaagag agaagatttg
    28921 atgtctttat gggaaatggc ttattcacaa cttaatccag tttggaaaca gtatgatgct
    28981 ccctattatg atgattatca gtatttttca aattttaaag aattcgaact acaaaaatca
    29041 gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa actagttggg
    29101 actgtttcgc gttattgggt atgtaaacaa acaagatgga tggaattggg aattggtatt
    29161 tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca gtggatagat
    29221 aggacgtttc aggattactt ggagttggag catctgggtt tgacaacttg gtcagggaat
    29281 attggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca tattccaaaa
    29341 gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt gagagaagac
    29401 tgggagaaaa taaatgacgg ttattatcaa atcaatggaa actcctaaag agatagaagg
    29461 taaatccctt gttcactggc aaacgtggag agagtcttat gatgaccttt tgcctgcgga
    29521 atttcaggat acaatgacat tagaaagatg tcgattcttt agtcaaaagt atccagaaaa
    29581 tacattgatt gcgatggatg gcgtgaaggt ggttggtttt atcagttatg gcaattttcg
    29641 tgatgagact attcaagctg gtgaaattat tgctttatat gttttaaaag actattatgg
    29701 aaaaggtatc gcacaaaagt taatgaaagc agctttgact gctcttaatc atttttctga
    29761 aattttctta tgggtattga aagataacaa gcgcgccatt gctttctatc aaaaaatggg
    29821 ttttactttt gatggacaag aaaaaatact tgaacttgga aagcctataa aggaaaaacg
    29881 aatggtgttc tattctaaat aattttaaaa aagtaaaaga taatatctct ggtagtaagt
    29941 ctgaaaattt aataaattag aaagcgagta aatttatgtc ccgttcccaa ttaacaattt
    30001 taacaaatat ctgtctgatt gaagacctcg aaactcagcg cgtggtgatg cagtatcgcg
    30061 cccctgaaaa caatcgctgg tctggttatg cctttcctgg aggtcatgta gaaaatgatg
    30121 aggcttttgc ggagtctgtc attcgtgaaa tctacgaaga aacagggttg actatccaaa
    30181 atcctcaact tgtcggcatt aaaaattggc cactagatac aggtgggcgc tatattgtca
    30241 tttgttataa ggcgactgag ttctctggta cccttcaatc ttcagaagag ggagaagttt
    30301 cttgggtgca aaaagaccag attccaaact taaatctggc ctatgatatg ctaccattga
    30361 tggaaatgat ggaagctccc gacaagtcag agtttttcta tcctcgccgt acagaagacg
    30421 attgggaaaa gaaaatcttc tagtctttta ctaaataacc tagctgatcc aaggcctcct
    30481 cgatatagtg gaggtcttgt tgtgtttcgg cttcgactag gtggtaatgg atgccatctg
    30541 tcaattcaga tagaggtcta aagtcagaat gctcgacttg ttctagaaaa tgttgcacat
    30601 ctctgcgaca agacagttta agcaaggttt caatttctcc ataaacggga tggtcaatca
    30661 aggtattctg gacatgccca ccattatcga caatagcaag gagttcctga ccgatttctt
    30721 caacttcatg tttcactttg aaaagtttgt gaacataagg attggtatca atttgcttat
    30781 agatgtagcc acgattggtg gataggatag gagcgccatc ggctctcaaa attgcaatgt
    30841 cctgcacaat gacctgacgt gtgacatgaa aatgttccgc caaactttgg ccattaaggg
    30901 ctttaggagc ttctttcaag agttggagca gggcttgttt gcgatctttt gtcatagctt
    30961 ttccttttaa cggcgttttc gaagcacttt atagacagct agtgctaatg tatagtctac
    31021 catactatgg ataattgtgc caaatccaac tagtacaaat agaacataga acatattttc
    31081 tacattggta cccgaagttg cgtaaaaaag gacacaggct aatacttcag caagggcatg
    31141 aacaacagcc aaaacaaaat tgaaaaccca ggaagatttt ggtttatcta gggtatcggg
    31201 gaatttttgt aggtaaagag ctcctaaagc accaaaagat atatgggaaa aagcccgaaa
    31261 aacgataacc atgggatagc cagccatcaa aaatccaaaa ctagaggcta ggatgacaaa
    31321 aactgccatc aagggcgaca agaacatggc tataaaaata gcgatgtggc tccccaaagt
    31381 ataggaagca ggtggaatga caatcttgaa aggcataaca attggaatca aaatcgcaat
    31441 agccgttaaa agggctgtca ttgtcataaa ttgtgtcttt ttccgtgtat tcacaagaat
    31501 ctccttttta actgcatata cactagtatg gtacaataaa ccagacaata aagcaagaat
    31561 ttacttgggt ttatagatca ttttttagtt aaaagttata gtagattgaa actagaatag
    31621 tccacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc
    31681 tgttcttatt tcgttttact atagtaaaga tttcattaaa aagaaactgt atagagcaaa
    31741 atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt ttgtagtcgt
    31801 ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga atttgttgag
    31861 ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa taggaagaag
    31921 attcctccaa ggacaaagat agtatttgtc aaggaaccaa gagccccagc taaaatcaga
    31981 ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat caaaatacgt
    32041 gggacaatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg agagaagagg
    32101 tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc catcaaaaat
    32161 ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac aggaatatga
    32221 acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct cagaaagtgt
    32281 atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg ttttttcatc
    32341 gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc ctcgtccgtg
    32401 gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt aggtttctaa
    32461 tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca tagcaggagc
    32521 tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca tgttgtccgc
    32581 aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga taaataaatc
    32641 tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttctt tcatgacatc
    32701 caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa actctgtagc
    32761 agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac tgactaaatc
    32821 tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg ccatagtttt
    32881 cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat ttcttcttta
    32941 gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg acctgctgaa
    33001 atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag actttttcgt
    33061 gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc aatcagatga
    33121 atagtaggat tccattcctt gactagggat atgattttgg gtgtcttttt aaggaacaaa
    33181 acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct taaaaattct
    33241 tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg agtgtagtca
    33301 gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg catttctatt
    33361 agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg ctctggcttc
    33421 agagctcgtt ttgtcgtaat taaacaaact tcatgccctg cagaaagcaa agtctctgtg
    33481 ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct atcgatagct
    33541 tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac aaaaataagc
    33601 ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttacta tagtttcaaa
    33661 ctataaagcc atataaaatt taagaaagga ctctaaaagt cttaaaaaca gagatattta
    33721 cgaacgttta gagagtttta agatgttaaa aatcttgttt tgtgatataa tgaattatca
    33781 tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca gagtattgag
    33841 ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttacgacga tttggagttg
    33901 tacggaaagt acaaggctaa actcagcttt gataaaattc gggcagttga gagcaatcca
    33961 gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga aggaaagtcg
    34021 acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac catgattgct
    34081 atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc tggtggtggg
    34141 tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga tatgcatgct
    34201 attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca ccaagggaat
    34261 gagctgggaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt gaacgaccgt
    34321 gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc acgtgaggat
    34381 ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc aacggacatc
    34441 gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga ccgtacgcct
    34501 gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa ggatgctatt
    34561 aagccaaact tggttcagac aatttacggt acacctgcct ttgtacacgg tggtccattt
    34621 gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct tcacttggct
    34681 gattacactg ttactgaagc tggttttggt gcggaccttg gtgctgagaa attccttgat
    34741 atcaagacac caaacttgcc aacatctcca gatgcagttg ttattgtcgc aacccttcgt
    34801 gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa tgtagaggca
    34861 gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa gttcggtatt
    34921 ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat tgcagtctta
    34981 aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg ggctgatgga
    35041 gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga aaatccagct
    35101 aactataaac gtttgtacga taatgacctt tctgtccaag aaaagattga aaaaattgtc
    35161 actgaaatct atcgtggtag caaagtgaac tttgagaaga aatctcaaac acaaattgct
    35221 caaatcgttc aaaacggttg ggacaaattg ccaatctgta tggctaaaac tcaatacagt
    35281 ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac cattcgtgaa
    35341 ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt tatgaccatg
    35401 ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga tggaactgta
    35461 ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata atatccaagc
    35521 tcattttttc tcagactgca agcagttcat caataagatt tatactcttc gaaaatctct
    35581 tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactctgt cagttctatc
    35641 cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gctctttgat
    35701 tttcattgag tataagtaga tagaaaagtt atatactatc tattgaaaat attataaatc
    35761 agatacaaag acaggtgaaa ccttctgtgt tatactagag atatgttaga tttgaaagaa
    35821 tacggtatcg tcatgtggcc ggaggagaaa gtcatttctt tccgtgagaa acttctcgct
    35881 tggtatgatg aaaacaaaag agatttgcct tggaggagaa gtaaaaatcc ttatcacatc
    35941 tgggtatctg aaatcatgct tcagcagacc agggtggata cagttatccc ttactacgaa
    36001 agattcctgg actggtttcc aactgtcgaa agtctggcaa ctgcgcctga ggagagttta
    36061 ctgaaagctt gggagggctt gggctattat tctcgagttc gcaatatgca ggctgcagcc
    36121 cagcagatta tgactgactt tggtggccaa tttccaaata cctatgaagg aatttccagc
    36181 ttgaaaggga ttggacctta cacagcagga gccatttcca gtattgcttt taacttgcct
    36241 gagccagctg tagatggtaa tgtcatgcgg gtcttggcgc gtctgtttga agtcaaccac
    36301 gatattggga ttccaagtaa tcgaaaaatt tttcaggcaa tgatggagat cttgattaat
    36361 ccggatcgtc cgggtgattt taatcaagcc ttgatggact tagggtctga tattgagtct
    36421 cctgtaaatc ccagacctga agaaagccca gtcaaggact ttagtgcggc atatcagaat
    36481 ggaaccatgg accgttatcc aattaaatct cctaagaaaa agccggttcc tatttatctt
    36541 aaagccttag ttgtgaaaaa ttctcaagga caatttttac ttgaaaaaaa tgaaagcgaa
    36601 aagctcttgg caggtttttg gcatttcccc tttatagaag ttgataactt ttcgcaagaa
    36661 gagcagtttg acctctttca tcaggttgcg gaagaaagtg tgaactttgg ccccagtcca
    36721 gaagagagtt tccagcagga ctatgaccta gatgttgatt ggcttgatgt ttgttttgat
    36781 acagtccagc atgtttttag tcatcgaaaa tggcatgtac agattgtagc aggtcaggtg
    36841 agtgacttcc atgatttttc agatagggaa gttcgttggc tttcaccaga agaattcaag
    36901 aattacccac ttgccaaacc ccaacaaaaa atctggcagg cttatgcaca agccaactta
    36961 gacagtagcc aagactagct attgtgtctt ctgactattt tttggtataa tagtagagaa
    37021 aaaggtgaac atatgaaaaa aatactaatt gtagatgatg agaaaccaat ctcggatatt
    37081 atcaagttta atatgaccaa ggaaggttat gaagttgtaa ctgcttttaa tggtcgtgaa
    37141 gcgctagagc aatttgaagc agagcaacca gatattatta ttctggattt gatgcttcca
    37201 gaaattgatg gtttagaagt tgctaagacc attcgtaaga caagcagtgt gcccattctt
    37261 atgctttcag ccaaagatag tgaatttgat aaggttatcg gtttggaact tggggcagat
    37321 gactatgtaa cgaaaccctt ctccaatcgt gagttgcagg cgcgtgttaa agctcttctg
    37381 cgtcgttctc aacctatgcc agtagatggt caggaagcag atagtaaacc tcaacctatc
    37441 caaattgggg atttagaaat tgttccagac gcctacgtgg ctaaaaaata tggcgaagaa
    37501 ctagacttaa cccatcgtga atttgagctt ttgtatcatt tagcatcgca tacaggtcaa
    37561 gtcatcacgc gcgaacactt gcttgagact gtctggggtt atgactattt tggtgatgtc
    37621 cgcacagttg atgtgactgt acgacgtctg cgtgagaaga ttgaagatac gcccagccga
    37681 ccagagtata tcttgacgcg ccgtggtgta gggtattaca tgagaaataa tgcttgattt
    37741 actgaaacaa accattttta ccagagattt tatctttatc ctgattttgt taggtttcat
    37801 ccttgttgtg accctcttat tactggaaaa tagacgtgat aatattcagt tgaagcaaat
    37861 caatcaaaag gttaaagatt tgattgcagg agattattcc aaggttcttg atatgcaagg
    37921 tgggtctgaa atcaccaata ttaccaataa tttgaatgac ttgtcggagg ttattcgtct
    37981 cactcaggaa aatctagaac aagagagtaa gaggctaaat agtattctgt tttatatgac
    38041 agatggggtt cttgcgacta accgtcgggg tcagattatc atgattaacg atacagccaa
    38101 gaagcaactg gggttggtta aggaagatgt tctgaataga agcattttgg aattgctcaa
    38161 gatagaagaa aactatgaat tgcgtgattt gattacccaa agtccagaat tgttgctaga
    38221 ttcccaagat atcaatggcg aatatttgaa ccttcgagtt cgctttgcct tgatacgtcg
    38281 agagtctggc tttatttcag gtttggtggc tgttttgcat gatacgacgg agcaggagaa
    38341 ggaagaacgc gaacgaagac tctttgtttc caatgttagc catgagttac ggactcctct
    38401 gactagcgta aaatcctatc ttgaagcctt ggatgagggg gctttgtgtg aaactgtagc
    38461 accagacttt atcaaggttt ctcttgatga gaccaaccgt atgatgcgca tggtgacgga
    38521 tctcctccat ctttcacgta ttgataatgc taccagtcac ctagatgtgg aactgattaa
    38581 cttcactgct tttattacct ttatcctcaa tcgttttgac aagatgaaag gacaggaaaa
    38641 ggagaaaaaa tatgagctgg tgagagatta tcccatcaat tctatctgga tggaaattga
    38701 tacagataag atgacgcagg ttgtcgacaa tattttaaat aatgctatta agtattcgcc
    38761 agatgggggt aaaatcactg tcagaatgaa gacaactgaa gaccagatga ttttatccat
    38821 ttctgaccac ggtttgggga ttcctaagca ggatttacca cgtatctttg accgtttcta
    38881 tcgtgtggat cgtgctagaa gtcgtgcaca aggtggtaca ggtctaggac tgtctatcgc
    38941 taaagaaatt atcaaacaac ataagggctt tatttgggcc aagagtgaat acggcaaggg
    39001 ttcaaccttt accattgtac tcccttatga taaggatgca gtgaaagaag aagtatggga
    39061 ggatgaagta gaagactaga atgagtgaaa taggctttaa atacagtatt ttagcgtcgg
    39121 gttccagtgg aaattctttt tatctggaaa cctcaaaaaa gaagctttta gtagatgcag
    39181 gcttgtctgg caagaaaatt accagtctgc tagctgaaat taaccgtaag ccagaagacc
    39241 tggatgccat cttgattacc catgagcatt cagatcatat ccatggagta ggcgttttgg
    39301 ctcgcaagta tggtatggat ctttatgcca atgaaaagac ctggcaagct atggaaaata
    39361 gtaaatatct tggcaaggtg gattcttcgc aaaagcatat ttttgaaatg ggtaaaacca
    39421 aaacctttgg agatatcgac atcgagagtt ttggtgtaag ccatgatgca gtcgcaccgc
    39481 agttctatcg ctttatgaag gatgataaga gttttgtcct cttgacagat acaggttatg
    39541 tcagtgaccg tatggcgggc attgtcgaaa atgcggatgg ttatcttatc gaggccaacc
    39601 atgatgtaga gattttgcga tcaggttctt acgcttggcg actcaaacaa cgaatcctat
    39661 ctgaccttgg tcacctttct aacgaggacg gtgctgaagc tatgattcgg acgctaggaa
    39721 atcgtactaa gaagatttac cttgggcatt tatctaagga aaacaatatc aaggaactgg
    39781 ctcatatgac catggtcaat cagctggctc aagctgatct gggagtcgga gtagacttta
    39841 aggtttatga tacctcacca gataccgcaa caccattgac agagatatag aaagaacgct
    39901 gagaaggtgt tcttttt
//
LOCUS       DAVLHM010000020        37764 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLHM010000020 DAVLHM010000000
VERSION     DAVLHM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.020"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            36..317
                     /locus_tag="VXE45_001057"
     CDS             36..317
                     /locus_tag="VXE45_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0789100.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            449..1393
                     /gene="manA"
                     /locus_tag="VXE45_001058"
     CDS             449..1393
                     /gene="manA"
                     /locus_tag="VXE45_001058"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0789101.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1433..2768)
                     /locus_tag="VXE45_001059"
                     /pseudo
     CDS             complement(1433..2768)
                     /locus_tag="VXE45_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            2996..3745
                     /locus_tag="VXE45_001060"
     CDS             2996..3745
                     /locus_tag="VXE45_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0789102.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3765..4220)
                     /locus_tag="VXE45_001061"
     CDS             complement(3765..4220)
                     /locus_tag="VXE45_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0789103.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4240..5415)
                     /locus_tag="VXE45_001062"
     CDS             complement(4240..5415)
                     /locus_tag="VXE45_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0789104.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5474..6319)
                     /locus_tag="VXE45_001063"
     CDS             complement(5474..6319)
                     /locus_tag="VXE45_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0789105.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            6444..7001
                     /locus_tag="VXE45_001064"
     CDS             6444..7001
                     /locus_tag="VXE45_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0789106.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7020..7487
                     /locus_tag="VXE45_001065"
     CDS             7020..7487
                     /locus_tag="VXE45_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0789107.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7576..8205
                     /gene="upp"
                     /locus_tag="VXE45_001066"
     CDS             7576..8205
                     /gene="upp"
                     /locus_tag="VXE45_001066"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0789108.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8379..8969
                     /gene="clpP"
                     /locus_tag="VXE45_001067"
     CDS             8379..8969
                     /gene="clpP"
                     /locus_tag="VXE45_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0789109.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9048..9296
                     /locus_tag="VXE45_001068"
     CDS             9048..9296
                     /locus_tag="VXE45_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0789110.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9397..10557
                     /locus_tag="VXE45_001069"
     CDS             9397..10557
                     /locus_tag="VXE45_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0789111.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGRDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10825..11694
                     /locus_tag="VXE45_001070"
     CDS             10825..11694
                     /locus_tag="VXE45_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0789112.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGAISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFEMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11698..12654
                     /locus_tag="VXE45_001071"
     CDS             11698..12654
                     /locus_tag="VXE45_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0789113.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12654..13418
                     /locus_tag="VXE45_001072"
     CDS             12654..13418
                     /locus_tag="VXE45_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789114.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13418..14128
                     /locus_tag="VXE45_001073"
     CDS             13418..14128
                     /locus_tag="VXE45_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789115.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14487..15143
                     /locus_tag="VXE45_001074"
     CDS             14487..15143
                     /locus_tag="VXE45_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0789116.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15251..16346
                     /gene="prfB"
                     /locus_tag="VXE45_001075"
     CDS             join(15251..15322,15324..16346)
                     /gene="prfB"
                     /locus_tag="VXE45_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0789117.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16364..17056
                     /gene="ftsE"
                     /locus_tag="VXE45_001076"
     CDS             16364..17056
                     /gene="ftsE"
                     /locus_tag="VXE45_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0789118.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17049..17975
                     /locus_tag="VXE45_001077"
     CDS             17049..17975
                     /locus_tag="VXE45_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789119.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYYKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18261..20441
                     /locus_tag="VXE45_001078"
     CDS             18261..20441
                     /locus_tag="VXE45_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0789120.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20493..21308
                     /locus_tag="VXE45_001079"
     CDS             20493..21308
                     /locus_tag="VXE45_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0789121.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            21448..22791
                     /locus_tag="VXE45_001080"
     CDS             21448..22791
                     /locus_tag="VXE45_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0789122.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDRNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23168..24358
                     /locus_tag="VXE45_001081"
     CDS             23168..24358
                     /locus_tag="VXE45_001081"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0789123.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24911..25846
                     /locus_tag="VXE45_001082"
     CDS             24911..25846
                     /locus_tag="VXE45_001082"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0789124.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25880..26917
                     /locus_tag="VXE45_001083"
     CDS             25880..26917
                     /locus_tag="VXE45_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0789125.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27090..27695
                     /locus_tag="VXE45_001084"
     CDS             27090..27695
                     /locus_tag="VXE45_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0789126.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27852..28382
                     /locus_tag="VXE45_001085"
     CDS             27852..28382
                     /locus_tag="VXE45_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0789127.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            28403..29488
                     /gene="rlmN"
                     /locus_tag="VXE45_001086"
     CDS             28403..29488
                     /gene="rlmN"
                     /locus_tag="VXE45_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0789128.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            29488..29970
                     /locus_tag="VXE45_001087"
     CDS             29488..29970
                     /locus_tag="VXE45_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0789129.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            29972..31513
                     /locus_tag="VXE45_001088"
     CDS             29972..31513
                     /locus_tag="VXE45_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0789130.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31569..32372)
                     /locus_tag="VXE45_001089"
     CDS             complement(31569..32372)
                     /locus_tag="VXE45_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0789131.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32455..32676)
                     /locus_tag="VXE45_001090"
     CDS             complement(32455..32676)
                     /locus_tag="VXE45_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789132.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(33155..33352)
                     /locus_tag="VXE45_001091"
     CDS             complement(33155..33352)
                     /locus_tag="VXE45_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789133.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLADD
                     SLAGDIILLWRIQFGTFTTET"
     gene            33522..33794
                     /gene="rpsP"
                     /locus_tag="VXE45_001092"
     CDS             33522..33794
                     /gene="rpsP"
                     /locus_tag="VXE45_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0789134.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33814..34053
                     /locus_tag="VXE45_001093"
     CDS             33814..34053
                     /locus_tag="VXE45_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0789135.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34630..35418
                     /locus_tag="VXE45_001094"
     CDS             34630..35418
                     /locus_tag="VXE45_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0789136.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            35449..35967
                     /gene="rimM"
                     /locus_tag="VXE45_001095"
     CDS             35449..35967
                     /gene="rimM"
                     /locus_tag="VXE45_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0789137.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35957..36676
                     /gene="trmD"
                     /locus_tag="VXE45_001096"
     CDS             35957..36676
                     /gene="trmD"
                     /locus_tag="VXE45_001096"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0789138.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36688..37026
                     /locus_tag="VXE45_001097"
     CDS             36688..37026
                     /locus_tag="VXE45_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789139.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(37057..37377)
                     /locus_tag="VXE45_001098"
     CDS             complement(37057..37377)
                     /locus_tag="VXE45_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789140.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37475..37690
                     /locus_tag="VXE45_001099"
     CDS             37475..37690
                     /locus_tag="VXE45_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0789141.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
BASE COUNT        11580 a         6966 c         8207 g        11011 t
ORIGIN      
        1 agtttagtat tatcgtagaa aatggactcg gtgctatgga tacaccggat gagaatggtt
       61 atgtagcaga tgactatcgg attacttact tagaggccca catcaaggcc atgcgagatg
      121 ccatttacca agatggggtt gacttgcttg gttatacgac ttggagctgt atcgatccgg
      181 tttcagctgg cacaggggaa atgaataagc gctatggctt tatctatgta gatcgagata
      241 atgtaggaaa tgggactctc aaacgtagca agaagaagtc cttctattgg tacatgtcat
      301 ttatagcaat ggtgtaagca tcgagtagag cacatttgtt tactattttt ataaaatctt
      361 ctccctgctt tataagatgt aaaaaagagt tcaaatggaa ctcttttttt gctataatga
      421 ggggagaaaa atcagacagg agattaagat gtcagaacca ttatttttac aatcagttat
      481 gcaagaaaaa atctggggtg gtaccaagtt acgtgatgag tttggctacg acatcccaag
      541 tgaaaaagtc ggagagtact gggctatctc agctcatcta aatggtgttt ctaaagttgc
      601 caatggtcgt tacgagggaa cagatcttgc tactttgtat gcggaacacc gtgaattatt
      661 tggcaatcgt ccagaacctg tatttccgct tttgaccaag atcctcgatg ccaacgactg
      721 gctcagtgtc caagttcacc cagacgatgc ttatggactc gagcatgaag gcgaacttgg
      781 aaaaacagaa tgttggtaca tcattgcagc agatgaaggt tcagagatta tctacggtca
      841 caatgccaag tcaaaagaag aactccgcca gcaaatcgag gataagaact gggatgcgct
      901 gttgacaaaa gtgccagtta aagcaggaga tttcttctat gtaccaagcg gtaccatgca
      961 cgctatcggg gcgggtatct tgattcttga aacccagcag tctagcgata ccacttaccg
     1021 tgtctatgac tttgaccgta aggatgacaa gggcaattta cgtgaacttc accttgaaaa
     1081 atctatcgat gtcttgaaca ttggtgaacc cgcaaatagc cgtccagtga caatcaaagc
     1141 agatgatcta cgttccactc tccttgtatc caatgatttc ttcgcagttt acaaatggga
     1201 aattactgga aaagttaact ttgaaaagac agctgactac agcttgttga gtgtcttggc
     1261 tggtcaaggt cagctaactg ttgacgggaa aaattatcca attcaaaaag gcagccactt
     1321 tatcctacca agtgatgttg aagcttggac tctggaaggg caaggtttgg aattgattgt
     1381 tagccatcca taaaaagaaa gggcctgagt tcactactca agtccttttt gattacataa
     1441 attgggcaat gaagaccaca atgatgatga ttggaatgac gaaacgaaga aacgaagaag
     1501 gaagagccag acttggaaca gtccttgttt ccatgctctt tcatcgagat ggagttcctc
     1561 cattgcaaga gcctttttaa agatatagcc tgtaaaaagt gaaaggtaga gagctccaaa
     1621 tggcatgagg agattggaaa ccaagaagtc catagcgtca aagaaggtct taccaaaaat
     1681 gtgaacatcc gccatgacac cgtaagatag ggctgaagga atgccaaaga caaaggtcaa
     1741 aattcctaaa ataacactcc atttggcacg tttgctgtta tcctggttgg tgatattgcc
     1801 cacattgatc tccagcatca cgacagaaga agtgacagtc gcaaagaggg agcggacgta
     1861 gaaaatggtt ccaaaaggca tcttgtcaaa gagttgaggc aagacgataa agagcaggct
     1921 gggtccccct tcagactgga tattgaaggg ggatcgagct tggaaaatgg ctagacctgc
     1981 catgatggat atcgagatat tcatggctac gatggagatt cctgactgga ctagattggt
     2041 tttcttgtcc aagtaagaag cataggtcaa catgactgta acccctagtg agagggcaaa
     2101 gaaagattgt cccagagcat agaggagacc agcgctagtc agttttgaaa agtctggttt
     2161 gaggaagtaa agaacccctt ccatggcatt tggcaaactg agagagcgac tgatgataaa
     2221 aacaaagacg ataaagagca ggggcatcat gactttcgaa gctctttcaa tccctttttg
     2281 aaccccacgt gatacaatga agatattcaa taggataaag gccgcttgag ctcctagggc
     2341 aatggctgga tttgaaatga ttgaagtaaa taactgagca taatcacccg ttccaccaag
     2401 ttggaacaat ttcccaaact caatacctag atagactaga atccatcctc cgataacact
     2461 gtaaaaagat aagaggataa agagggcaaa ggcgccaatc caaccgataa agttgtactt
     2521 gttattcttg cccagttttc caaaggtttt gatagcggaa acgccagcac tacggccaag
     2581 ggcaaactca gccagcagga gagggaaacc gattaaaata gtggaaatga gaaagattag
     2641 taaaaagcct ccaccgccat tagcagcagt catgtaggga aacttccaaa cggaaccaag
     2701 cccgatggcc agccagcaga tgctagaata aaaccaagtt tcgaccccca ttgtgatttt
     2761 tctgacatag ttaaactctg atctcctttt tcaaaataag aaaaagctac ttgagttgtc
     2821 aaatagcctt ctgtttgatt gatagacttg actatcctat catgttttct aaggtctgtc
     2881 aagaaaatca ttttcaagtt ttcacacctt tctcaaaaaa gttaaaaaat tttctcaaaa
     2941 acgcttgact ctgacctaag gggaggggtt atactatcat tgtaaggagg aaatcatgta
     3001 ccatataaaa gaagctgcgc agctttcagg tgtctctgtc aagaccctgc atcactatga
     3061 caagatagga ctcttggtcc ccttaaagtc ggaaaacggc tatcgaacct acagtcaaga
     3121 ggatttggaa cgccttcagg tcattcttta ctacaaatat ctaggctttt ctttagagaa
     3181 aatagcagag ctgttaaagg aagaaaggac agatttattg ccccatttga ctaggcagtt
     3241 ggactatcta actcgcgaaa ggcaacatct ggataccttg atttccacct tgcaaaaaac
     3301 tattcaagaa caaaaaggag aaagaaaaat gaccattgag gaaaaattca cgggatttag
     3361 ctatcaagac aatcaaaaat accaccaaga agcggtagag aaatatggtc aagaagtcat
     3421 gggacaagcg ctcgaacgcc aaaaaggtca cgaagacgag gctacggccg cctttaacca
     3481 agtctttcaa actttggcac aaaatcttca agttggttta cctgcaacag caaccgaaaa
     3541 ccaggagcaa gcagccaagc tcttgcaagc cattcgcact tatggatttg actgctctat
     3601 tgaggtattc ggtcatatcg gtaaaggtta cgtctataac ccagagttta aggaaaacat
     3661 tgacaagttt ggttctggaa cagcccagta cacgtcagat gccattgcag cttacgttca
     3721 gacaaatgca gaaaaaatag gctaggaatt tcctagccta ttttttactt caaatcataa
     3781 agccagtcgt caccgttttt gtagtaaaag aattcactga gatcttcttc tagaaacaca
     3841 cgaagcatat cagacatatc atcggttgca agttttagat gagaaagatt ttcaaagtcc
     3901 tcccaccaaa ctttcccttc gtctgaagac tggagttcac cagtaaagtg ttctgtcttg
     3961 taaaaaagga cgacataacg ataatccttg tcgtcatacc agtttttgat accacagagt
     4021 tggggtttgg aaatgatcag accagtttct tctttcactt cacgaatgac agcatcgaca
     4081 aaggattcgc cacgttcaac atgaccacca ggaaaagtaa tgccaggcca gtcgggacta
     4141 actcggtctt ggaccaggac cttatctccg tttttaatca tacacatgtt aacaaattcg
     4201 actgcctctc ttctgttcat tcttcacaac ctttaatctt taatcataat gcagacttcc
     4261 cgccacccag ccggtacaga gggcagaagt gatgttaaag ccacccgtgt gggcattgat
     4321 atccataact tcgcctgcaa agtggaggcc aggtaccagc ttactttcaa gggttttagg
     4381 attgatttcc ttgagactga ctccaccctt ggtaacaaag gactttgcaa gggacatttt
     4441 tccagttaca ggaattttaa gttctttaat ggactgaaca agttgttctc gttccttttc
     4501 agtcagctgt ttgacttttt caggatatcc ttgtacaaaa aattcggcca agcgttctgg
     4561 taacaaggtt tttaaagcgt ttttcaagga tttttcccga ttttcttcta gaaatgtaac
     4621 caagtccttc tcagaaagtt gaggcaaaac atcgagtgag agaacctccc cacctttgac
     4681 aaagctagac atgcgtaggg cagcaggacc tgacaaacca aagtgggtaa agagtaaatc
     4741 atgagtgatg acatgcttac cataacttag ggtcacatcg tccagagaaa tcccttgtaa
     4801 ggctttatgt ggaaaatctg ttaataaagg actttcagca gcctcaagct cggtgatggt
     4861 atgcttaaaa tggcgagcaa tctcgtgacc aaaaccagtc gaaccagtcg aaggataaga
     4921 cttaccacct gttgtgacaa tgagtttctc acaagtgaag gtttgatccg ctgacttaag
     4981 gacaaactgg tcatctactt ttttaacaga aacgatttct atttgagtag caacttgacc
     5041 acctagttcg gtgattttct tttccaaagc ttcgataata gtccgagact tgtcactggc
     5101 tggaaagacg cgtccgtggt cttcgacctt aagtttaaca ccattttctg taaaaaagtt
     5161 gatgatgtca tgattatcga actgggagaa aacactgtaa agaaagcgtc cgtttccagg
     5221 aattccagct agcaggttgt ctaagctacc attgttggtc acattgcaac gtcccccacc
     5281 agtcccagct aatttttttc caagtttccg atttttttcg atgaggaggg ttttctgtcc
     5341 ataaaagcta ctggaaatcg tagccatcat accagcaggt cccccaccga tgacaatagt
     5401 atcaaaatgt ttcatagctc tattgtacca caaaaaaaca agagatgatg gtcacctctt
     5461 gtcaagaatg caattaatca atttcatagc ccatcagcaa accgccatct tctgcataga
     5521 aactgcagag accagaggtt ggtagaattt taatatccgc ttgtgggaag gtttcacgga
     5581 ttcgctctga gagctgttga caacattttt cgttattgcg ttgggccatg acaatacggc
     5641 caccagcata tccagctttt actaactcat cataggcagc ttgaactgat ttctttgatc
     5701 cccttgcttt ttgtagcaat tcgagagtcc cagtttcact agcttttccg accatacgaa
     5761 tgttgagaag gccaacgacc gtaccgataa gcttgctcaa acggccgttc ttcaccaagt
     5821 tatcgacttt ggctaggaca aagagcaact tagttttttc ttgataggcg gtgatagctt
     5881 caaccacttc ttcaaaagac aagccctggt caatcaagtc attcaatttt tctacgagta
     5941 ggtcaacttc accaccagca gataaactat caatcacatg aatcttagtg tcaggatggt
     6001 cttccagata aatattcttt gctagttgag cactattgtg actgccagaa agggtacctg
     6061 tgatggttac taggaaaatg tttttggcac cttcaaatgc tcgcaaatag tcatctgggc
     6121 ttggacaagc cgattttgaa gcttctgcag ttgcatacat ggtttccatc atttggtcaa
     6181 tatcgagact ggcgtcatca acaaagacct gatcagctac ttgaatggtt aaggggacac
     6241 ttacaaaggt tgtgttaata gctggtgttg gcagttgacg ataatcacaa ccagagtcag
     6301 caataatttt ccaagtcata gaaattctcc atctttgtca gttatacatt gacaaaggtt
     6361 ctgtcttttt ttacaattat atcatgaaaa cccttgaaac aaaagcatca tccgtctgtt
     6421 gtgacaagta gaaagaaaat gttatgtctg aacgtagaat ctctgaaaag tctcttgaaa
     6481 atctcagaaa atcaaaccaa gaatccaatt tattaaccag agaagccatt gaaacagccc
     6541 tcttgcaact cttggaaaaa aaggagctga ccaagattag tatttctgaa ttggtcaaac
     6601 gtgcaggtgt ttcgcgtgcg gccttttatc gcaattatga ctccaaagag gaaattttag
     6661 agagcgtctt taaacgaact gtccacaata ttatggaaca gctgcatcat tacgatttaa
     6721 agacagacct ttatttggtt tgggttcacc ttttccggga ggccagaaag gaagctagag
     6781 tgattcaatt ggccttggat taccatctgg aaaaaatctt tgtccaagcc atgcaggaat
     6841 ttctagaaaa ataccatggg aaatcaaaag gtgtcagctc ttatcttcat tccttctgga
     6901 gctcagccat cgtctctgtc cttctaaaat ggatcaagga tggcatgaag gtaccagctg
     6961 aaaagattgc agatttaggt ttaccatttt ttaaaaaata gagaaaaagg agaaaagaga
     7021 tgactgaaaa aagactggcc tgggatgagt attttgcagc ccaagcccta ctaattgcga
     7081 atcgttccac ttgtaaacgt gctaaagtgg gcgcgattct ggtaaaagat aataaggtta
     7141 tttccactgg ttacaatggt tcggtgtcag ggactgagca ttgtattgat cacgaatgtt
     7201 tggtcattga aggccactgt gttcgcaccc ttcacgctga ggtcaatgct atccttcaag
     7261 gtgctgagcg tggtgttccc aaaggcttta cagcctatgt aacccatttt ccttgtctca
     7321 actgtacaaa acaattgctt caggtcggct gcaagcgcgt ggtttatatc aaccagtacc
     7381 gaatggacga ctacgcccaa tacctttatc aagaaaaagg gacagaattg acccatttac
     7441 cacttgagac agtacagaca gctcttaaag aggctgatct aatgtaaaaa ttatcaaaaa
     7501 taaatggctt agaaagattt ttaaaccgtt ttttggtata ataagaagaa taaattgaaa
     7561 gaaggaattc caaaaatggg aaaaattgaa gttattaatc acccactgat tcaacacaaa
     7621 ttgtcaatct tgcgtcgtac agatacttct acaaaagctt ttcgtgagct agtagatgag
     7681 attgcaatgt tgatggggta tgaagtactt cgtgatcttc cactagaaga tgtggaaatc
     7741 gaaacaccaa ttacaaaaac agttcaaaaa caattggcag gtaagaaatt ggccatcgtc
     7801 ccaatcttgc gtgcaggtat cgggatggtt gatggtctct tgagcttggt tccagctgct
     7861 aaagttggcc acatcggtat gtaccgtgat gaagaaacac ttcaaccagt tgaatacttg
     7921 gtgaaattgc ctgaggacat tgaccaacgt caaattttta tagtagaccc aatgttggca
     7981 acaggtggct cagcaatctt ggctgttgat tctcttaaaa aacgtggcgc atcaaatatc
     8041 aaatttgtct gccttgtatc tgctccagag ggtgtaaaag cccttcaaga agctcatcca
     8101 gatgtagaaa tctttacagc agccttggat gaacgtttga acgaacacgg ttatatcgtt
     8161 ccaggtcttg gagatgctgg agaccgcttg ttcggtacaa aataagatcg aaaagaagaa
     8221 tgacttggaa aagtatttcc agtcacgaaa ggaggttggg tttttgtttc tgtctaatga
     8281 aagcagagca aaaatttgac cttttttgac caagatatta taatagtctt atcttcagtc
     8341 agttgaccaa caaaattaaa actcaaaagg agaaatgaat gattcctgta gttattgaac
     8401 aaacaagccg tggagaacgt tcttacgata tttactcacg tcttctcaaa gaccgcatca
     8461 ttatgctgac aggtccggtt gaagacaata tggctaactc tgttattgcc caattgcttt
     8521 tcttggatgc ccaagatagt acaaaagata tttaccttta tgtcaataca ccaggtggtt
     8581 ctgtttcagc tggtttggca atcgtagata ccatgaactt tatcaaggca gatgtccaaa
     8641 ccatcgttat gggaatggct gcatctatgg gaacagtcat cgcatcaagt ggagcaaaag
     8701 gcaaacgttt catgcttcca aatgctgaat acatgattca ccaaccaatg ggcggtacag
     8761 gtggtggtac ccaacaaact gatatggcta tcgctgcaga acacttgctc aaaactcgta
     8821 ataccttgga aaaaatcttg gctgaaaatt caggtcagtc aatggaaaaa gtccatgcag
     8881 atgcagaacg tgataactgg atgagcgccc aggaaacact tgaatatggc tttattgatg
     8941 aaattatggc caacaattca ttgaactaat gatgatagaa ggcaaactcg actgggtttg
     9001 ctttttttgg tataataggg agagatttct tagaaagagg atttatcatg tttgaaaaag
     9061 tcaatcgctc tggcttgatt atctatcttt actataatcg tgatgccaaa aaattgcagg
     9121 attatggaga tattacctat cattccaaga aacatcgtta cttacaactc tatgttccaa
     9181 ctcaagaagt ggagcaattg gtcggacgct tgagcaagga aaaatttatt aaaaaagtta
     9241 gggtttgtca tatccaagag ttggaaacac cctttgtggg caatctttat cgataggaaa
     9301 acgttatcat agaaaaagtt caaggaaaac attgacaatt ttctgataat tcggtatatt
     9361 cttaacagac tatttaagaa ataaggagac aaaaagatga agaaaaaatt tgccctatcg
     9421 tttgtggcgc ttgcaagtgt agcacttctt gcagcctgtg gagaagtgaa gtctggagca
     9481 gtcaacactg ctggtaactc agtagaggaa aagacaatta aaatcgggtt taactttgaa
     9541 gaatcaggtt ctttagctgc atacggaaca gctgaacaaa aaggtgccca attggctgtt
     9601 gatgaaatca atgccgcagg tggtatcgat ggaaaacaaa tcgaagtaat cgataaagat
     9661 aataagtctg aaacagctga ggctgcttca gttacaacta accttgtaac ccaatctaaa
     9721 gtatcagcag tcgtaggacc tgcgacatct ggtgcgactg cagctgcggt agcgaacgct
     9781 acaaaagcag gtgttccatt gatctcacca agtgcgactc aagatggatt gactaaaggt
     9841 caagattacc tctttattgg aactttccaa gatagcttcc aaggaaaaat tatctcaaac
     9901 tatgtttctg aaaaattaaa tgctaagaaa gttgttcttt acactgacaa tgccagtgac
     9961 tatgctaaag ggattgccaa atctttccgc gagtcataca agggtgaaat cgttgcagat
    10021 gaaactttcg tagcaggtga cacagacttc caagcagccc ttacaaaaat gaaagggaga
    10081 gactttgatg ctatcgttgt tcctggttac tataatgagg ctggtaagat tgtaaaccaa
    10141 gcgcgtggca tgggaattga caaaccaatc gttggtggtg atggattcaa cggtgaggag
    10201 tttgtacaac aagcaactgc tgaaaaagca tcaaacatct actttatctc aggcttctca
    10261 actactgtag aagtttcagc taaagctaaa gccttccttg acgcttaccg tgctaagtac
    10321 aatgaagagc cttcaacatt tgcagccttg gcttatgatt cagttcacct tgtagcaaac
    10381 gcagcaaaag gtgctaaaaa ttcaggtgaa atcaagaata accttgctaa aacaaaagat
    10441 tttgaaggtg taactggtca aacaagcttc gatgcagacc acaacacagt caaaactgct
    10501 tacatgatga ccatgaacaa tggtaaagtt gaagcagcag aagttgtaaa accataatag
    10561 aaaaatgttg aaatagggaa tgagcctttg actcactccc tgtttcgata tttaatactc
    10621 ttcgaaaatc tcttcaaact gcgtcaacgt cgccttggat tatatatgtg actgacttcg
    10681 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    10741 tgctctttga ttttcattga gtataagaac ctatcaaaaa gtgagggaaa accctcggaa
    10801 ttataaatag aaagagtgaa tcttatgctc caacaactcg taaatggttt gattctaggt
    10861 agtgtttacg cgctgttagc cctaggatat accatggttt acggaattat caagctcatc
    10921 aacttcgccc atggtgatat ttatatgatg ggagccttta tcggttattt cttgatcaat
    10981 tctttccaaa tgaatttctt tgtagcgctt attgtagcta tgctagcgac agctattctt
    11041 ggtgtcgtga ttgagtttct tgcttaccga cctttgcgcc actctactcg tattgctgtt
    11101 ttgattacgg ctattggggt ttctttccta ttggagtatg gaatggtcta tctggttggt
    11161 gccaataccc gtgccttccc tcaagcgatt caaacagttc gatatgattt gggagcaatt
    11221 agcttaacaa atgtgcagtt aatgattttg gccatttcct tgattttgat gattttgtta
    11281 caagtcattg tccaaaagac taagatgggg aaagccatgc gtgcagtatc agtagatagc
    11341 gacgcggcac aattgatggg gatcaatgta aaccgtacga ttagctttac cttcgctttg
    11401 ggttctgctc ttgcgggtgc ggctggtgtt ctgattgctc tttattataa ctctcttgag
    11461 cctttgatgg gggttactcc aggtcttaaa tctttcgttg ccgcagtact tggtggtatc
    11521 ggaattattc ccggtgcggc tcttggtggc tttgtgattg gtctattgga aacctttgcg
    11581 acagcctttg agatgtcaga tttccgtgat gccattgttt atggaatctt gttgttgatc
    11641 ttgattgtcc gcccagctgg tatccttggt aagaatgtga aagagaaggt gtaaacgatg
    11701 aaggaaaatt taaaagttaa tattctatgg ttactccttt tgttagctgg ctatagcttg
    11761 attagtgtac tggtttcagt cggagtactt aatctattct atgtacagat tttacaacaa
    11821 attggaatta atattatttt ggctgttggt ctcaacttaa tcgttggttt ttcaggacaa
    11881 ttttcacttg gtcatgctgg tttcatggcg attggtgcct atgcagcagc tattattggt
    11941 tctaaatcac caacctacgg tgccttcttt ggagctatgc ttgtaggggc tttgctttca
    12001 ggagcagttg ccttacttgt cggcattcca accttgcgct tgaaggggga ctatcttgcg
    12061 gtagcaactc tgggtgtttc tgaaattatc cgtatcttta tcatcaatgg tggaagtctt
    12121 acaaatggtg cggcaggtat cttagggatt cctaacttta caacttggca aatggtttac
    12181 ttctttgtcg tgattacaac cattgcaacc ttgaacttct tgcgtagccc aattggccgt
    12241 tcaaccctct ctgttcgtga agatgaaatc gctgctgagt cagttggggt taatacgact
    12301 aaaattaaaa tcatcgcttt tgtctttggt gccattactg caagtattgc tgggtcactt
    12361 caggcaggat ttatcgggtc tgttgtaccg aaagattaca ccttcatcaa ctcaatcaac
    12421 gttttgatta ttgttgtatt tggtggactc ggttccatta caggtgcgat tgtttcggct
    12481 attgttctgg gaattttgaa tatgcttctc caagatgttg ctagtgtgcg tatgattatt
    12541 tacgctttgg ccttggtatt ggtaatgatt ttcagaccag gtggactcct tggaacgtgg
    12601 gaactgagcc tatcacgttt ctttaaaaaa tctaagaagg aggaacaaaa ctaatggcat
    12661 tacttgaagt aaaacagtta accaaacatt ttggtggtct aacagctgtt ggagatgtga
    12721 ctcttgaatt gaacgaaggg gaactggttg gattaatcgg tccaaacgga gctgggaaaa
    12781 ccaccctttt caaccttttg accggtgttt atgaaccaag cgagggaaca gtaaccctag
    12841 atggtcacct tttgaatggg aaatcacctt ataagattgc ctctttggga cttggacgta
    12901 ctttccaaaa tatccgtctc tttaaagatt taacagtttt agataatgtt ttgattgctt
    12961 ttggaaacca tcacaaacag catgttttta ctagtttctt acgcttacca gctttttaca
    13021 agagtgaaaa agaattaaag gataaagctt tggaattgtt gaaaatcttt gatttagatg
    13081 gtgatgcaga gactcttgct aaaaatcttt cctacggaca acaacgtcgt ttggaaattg
    13141 ttcgtgccct tgctacggaa cctaaaattc tcttcttaga tgaaccagca gcaggtatga
    13201 acccacagga aacagccgaa ttgactgagt taattcgtcg tatcaaagat gaatttaaga
    13261 ttacaatcat gttgattgaa cacgatatga atctggtcat ggaagtaaca gaacgtatct
    13321 acgtacttga atatggccgt ttaattgctc aaggaactcc agacgaaatt aagaccaata
    13381 aacgcgttat cgaagcttat ctaggaggtg aagcctaatg tctatgttaa aagttgaaaa
    13441 tctttctgtg cattacggta tgatccaagc agtccgtgat gtaagctttg aagttaatga
    13501 aggagaagtt gtttccctta tcggtgccaa cggtgcaggt aagacaacta ttcttcgcac
    13561 cttgtcaggt ttggttcgac caagttcagg aaagattgaa tttttaggtc aagaaatcca
    13621 aaaaatgcca gctcagaaaa tcgtggcagg tggtctttca caagttccag aaggacgcca
    13681 cgtctttcct ggcttgactg ttatggaaaa tcttgaaatg ggagctttct taaagaaaaa
    13741 tcgtgaagaa aatcaagcta acttgaagaa ggttttctca cgctttcctc gtcttgaaga
    13801 acggaagaac caagatgcag ctactctttc aggaggggaa caacaaatgc ttgccatggg
    13861 acgcgctctt atgtcaacac caaaacttct tcttttagat gaaccatcaa tgggacttgc
    13921 cccaatcttc atccaagaga tttttgatat cattcaagat attcagaagc aaggaacaac
    13981 cgtcctcttg attgaacaaa atgccaataa agcacttgca atctctgacc gaggatatgt
    14041 attggaaaca ggaaaaatcg tcctatcagg aacaggaaaa gaactcgctt catcagaaga
    14101 agtcagaaaa gcatatctag gtggctaaaa caatccagtg gattgtttta gtcggcagat
    14161 gaagattacg aagtaatcat caatatagtc cgggggccct ttttagtcgg tggatgaaga
    14221 ttgcgaagca atcatcaaat ccagaggatt gttttagccg gtagattgag attgcaaaca
    14281 aatctgcatc tacattgaaa gctgaatttc taataattga aaaaatcgaa tgaaacgtat
    14341 cttaccttca ttcagggagc tcgattttag agctcttttt gctagcttat tcatactttt
    14401 ttgaatttcg aaaaagaaat gtaagcgttt gatagattta caaaaagatt gtataatggg
    14461 gataagaata gaaaaggaga agtctcatgg cagttaaaga ttttatgacc cgcaaggtag
    14521 tttatattag tccagataca acagtatctc atgcagcaga tttgatgaga gagcaagaat
    14581 tgcaccgctt gcctgttatc gaaaatgatc aattggttgg tttggtgact gagggaacca
    14641 ttgcacaagc aagtccatct aaagcaacaa gtctttctat ctatgagatg aattatcttc
    14701 tgaataagac aaaagtaaaa gatgtcatga ttcgcgatgt tgtcactgtc tcaggctatg
    14761 ctagtctaga agatgcaact tatctgatgt tgaaaaataa gattggtatt ctccctgtcg
    14821 tagataacca tcaagtatac ggagttatta ctgaccgtga cgttttccaa gcctttcttg
    14881 aaattgcagg ttatggcgaa gaagggattc gtgtacgctt tgttacagaa gatgaagttg
    14941 gtgttcttgg aaaaattgtt tctttgattg tagaagaaaa tttgaatatc tcccatacag
    15001 tcaatattcc gcgtaaggat ggtaaggtca ttatcgaagt gcaaatcgat ggatcaattg
    15061 atttaccagc cttgaaagaa aaatttgaag caaatggtat tcaagtggaa gaaatcgctc
    15121 gcacttcagc aaaagtcttg taagaaggga agcccaaagg cttctttttt catgaaaagg
    15181 ggattagaga aaaagatgga aagaaatgat aaaatatgct ataatgaaat aatgtaaaaa
    15241 aggagtattt atggacattt cagtaattcg tcagaaaatt gacgcaaatc gtgaaaaatt
    15301 agcttctttc agggggtctc tttgacctcg aagggctaga ggaagagatt gccatcttgg
    15361 aaaacaagat gacagaacct gatttttgga acgataatat tgcggcccaa aaaacgtcgc
    15421 aagaattaaa tgaattaaaa aacacttaca ataccttcca taagatggaa gagttgcagg
    15481 atgaagtcga aattttattg gattttttgg ctgaagacga gtcagtgcat gatgaactgg
    15541 tagcgcagtt agccgaactt gataagataa tgaccagcta cgagatgact ctactcttgt
    15601 cagaacctta tgaccacaac aatgccatct tggaaatcca tccaggttct ggtggtactg
    15661 aggcgcagga ctggggtgat atgttgcttc gtatgtatac tcgttatggt aatgctaaag
    15721 gctttaaagt ggaagtgttg gattaccaag caggtgatga ggctggtatt aagtcggtaa
    15781 ctttatcatt tgaagggcct aatgcctatg gtctcctcaa gtcagaaatg ggtgttcacc
    15841 gcttagtgcg aatctcacca tttgactctg ccaaacgtcg ccatacctct ttcacatctg
    15901 tagaagtgat gccagaattg gatgatacta ttgaagtgga aatccgtgaa gatgatatca
    15961 agatggatac cttccgttca ggtggtgccg gtggacaaaa cgtcaataag gtttcaacag
    16021 gtgtacgttt aacccacatt ccaactggaa ttgttgtcca atcaacagtg gatcgtaccc
    16081 agtatggaaa tagagatcgt gccatgaaga tgttgcaggc taagctctat caaatggagc
    16141 aagataagaa ggctgcggag gtagattctc tcaaaggtga gaaaaaggag atcacttggg
    16201 gaagccaaat ccgttcttat gtcttcacgc cttatactat ggtaaaagat caccgaacta
    16261 gctttgaggt tgctcaggta gataaggtta tggatgggga cctagatggt tttatcgatg
    16321 cttatctcaa gtggcgaatt agctaagata gaaaggaact cacatgtcaa ttattgaaat
    16381 gagagatgtc gttaaaaaat acgacaacgg aacaactgct ctacgcggtg tttcggttag
    16441 cgttcaaccg ggggaatttg cttacatcgt aggaccttca ggagcaggga agtcaacttt
    16501 tattcgttct ctgtatcgtg aagtaaaaat cgataaagga agcctatcag ttgctggttt
    16561 taatctggtt aagatcaaaa agaaagatgt cccgcttcta cgtcgtagtg ttggggttgt
    16621 cttccaggat tataaactgt taccaaagaa aactgtctat gaaaatattg cttacgctat
    16681 ggaagtaatc ggggaaaatc gccgtaatat caaaagacga gtgatggaag ttttggactt
    16741 ggttggattg aagcataagg ttcgttcttt tccaaatgaa ctctcaggtg gggagcaaca
    16801 gcgaattgcg attgcgcgtg caattgtaaa taatcccaaa gtattgatag ctgatgagcc
    16861 aacaggaaat ctggatccgg ataattcatg ggaaattatg aatctcttgg aacggattaa
    16921 cctacaagga acaactattt tgatggcgac tcataatagc cagattgtaa ataccttgcg
    16981 ccaccgtgtc attgccattg aaaatggccg tgtcgttcgt gacgaatcaa aaggagagta
    17041 tggatacgat gattagtaga ttttttcgcc atttatttga agccttaaaa agtttgaaac
    17101 gaaatggttg gatgacagta gctgctgtca gttcagtcat gattactttg accttggtgg
    17161 caatatttgc atctgttatt ttcaatacag cgaaactagc tacagatatt gaaaataatg
    17221 tccgtgtagt agtttatatc cgaaaggatg tggaagataa tagtcagaca attgaaaaag
    17281 aaggtcaaac tgttacaaat aatgactact acaaggtata tgattctttg aagaacatgt
    17341 ctacggttaa aagtgttacc ttttcaagta aagaagaaca atatgaaaaa ttaaccgaga
    17401 taatgggaga taactggaaa atctttgaag gagatgccaa tcctctctat gatgcctata
    17461 ttgtagaggc aaacactcca aatgatgtaa aaactatagc cgaagatgct aaaaaaattg
    17521 aaggtgtctc tgaggttcaa gatggcggtg ccaatacaga aagactcttc aagttagctt
    17581 catttatccg tgtttgggga ctagggattg ctgctttgtt aatttttatc gcagtttttt
    17641 tgatttcaaa taccattcgt attaccatta tttcccgcag tcgcgaaatt caaatcatgc
    17701 gcttggtcgg agctaaaaac agttatatcc gtggaccgtt cttgttagaa ggagccttta
    17761 tcggtttatt gggagctatc gcaccatctg ttttggtctt tattgtttat caaattgttt
    17821 atcaatctgt caacaaatcg ttggtagggc aaaatctatc catgattagt ccagatttat
    17881 ttagtccgtt gatgattgcc ctactatttg tgattggggt tttcattggt tcattgggat
    17941 caggaatatc catgcgccga ttcttgaaga tttaggtaaa atagctgctt ttatgaggag
    18001 attgtaaaat ctcctttttt gctacaagag tttttgaaaa gagatgcgca gaagaaaaga
    18061 gcttccaaag aagtccccca gagaagactt cttgatggct aatttgaact tgaaatttga
    18121 ctcactagaa attttttaga aaaaagtgta atttttttat aaaagccttt acaaaaaaaa
    18181 ttaaagtggt ataattaaat tatagaaggt gcaaacgttt tcgtaaaacg tttgcctaaa
    18241 taaaaataaa ggagatttga atgatgaaag atacattcaa aaatgtcttg tctttcgaat
    18301 tttggcaaaa attcggtaag gctttgatgg tagttatcgc ggttatgccg gctgctggtt
    18361 tgatgatttc aatcggtaag tctatcgtga tgattaaccc aacctttaca ccacttgtca
    18421 tcacaggtgg aattcttgag caaatcggtt ggggggttat cggtaacctt cacattttgt
    18481 ttgccctagc cattggagga agctgggcta aagaacgtgc tggtggtgct ttcgccgctg
    18541 gtcttgcctt cattttgatt aaccgtatca ctggtacaat ttttggtgta tcaggcgata
    18601 tgttgaaaaa tccagatgct atggtaacta ctttctttgg tggttcaatc aaagttgctg
    18661 attactttat cagtgttctt gaagctccag ccttgaacat gggggtattc gtagggatta
    18721 tctcaggttt tgtaggggca actgcttaca acaaatacta caacttccgt aaacttcctg
    18781 atgcactttc attcttcaac gggaaacgtt tcgtaccatt tgtagttatt cttcgttcag
    18841 caatcgctgc aattctactt gctgctttct ggccagtagt tcaaacaggt atcaataact
    18901 tcggtatctg gattgccaac tcacaagaaa ctgctccaat tcttgcacca ttcttgtatg
    18961 gtactttgga acgtttgctc ttgccatttg gtcttcacca catgttgact atcccaatga
    19021 actacacagc tcttggtggt acttatgaca ttttaactgg tgcagctaaa ggtactcaag
    19081 tattcggtca agacccacta tggcttgcat gggtaacaga ccttgtaaac cttaaaggta
    19141 ctgatgctag tcaatatcaa cacttgttag atacagtaca tccagctcgt ttcaaagttg
    19201 gacaaatgat cggttcattc ggtatcttga tgggtgtgat tgttgctatc taccgtaatg
    19261 ttgatgctga caagaaacat aaatacaaag gtatgatgat tgcaacagct cttgcaacat
    19321 tcttgacagg ggttactgaa ccaatcgaat acatgttcat gttcatcgca acacctatgt
    19381 atcttgttta ctcacttgtt caaggtgctg ccttcgctat ggctgacgtc gtaaacctac
    19441 gtatgcactc attcggttca atcgagttct tgactcgtac acctattgca atcagtgctg
    19501 gtattggtat ggatatcgtt aacttcgttt gggtaactgt tctctttgct gtaatcatgt
    19561 actttatcgc aaacttcatg attcaaaaat tcaactacgc aactccaggg cgcaacggaa
    19621 actacgaaac tgctgaaggt tcagaagaaa ccagcagcga agtgaaagtt gcagcaggct
    19681 ctcaagctgt aaacattatc aaccttcttg gtggacgtgt aaacatcgtt gatgttgatg
    19741 catgtatgac tcgtcttcgt gtaactgtta aagatgcaga taaagtagga aatgcagagc
    19801 aatggaaagc agaaggagct atgggtcttg tgatgaaagg acaaggggtt caagctatct
    19861 acggtccaaa agctgacatt ttgaaatctg atatccaaga tatccttgat tcaggtgaaa
    19921 tcattcctga aactcttcca agccaaatga ctgaagcaca acaaaacact gttcacttca
    19981 aagatcttac tgaggaagtt tactcagtag cagacggtca agttgttggt ttggaacaag
    20041 taaaggatcc agtatttgct caaaaaatga tgggtgatgg atttgcagta gaacctgcaa
    20101 atggaaacat tgtatctcca gtttcaggta ctgtgtcaag catcttccca acaaaacatg
    20161 cttttggtat tgtgacggaa gcaggtcttg aagtattggt tcacattggt ttggacacag
    20221 taagtcttga aggtaaacca tttacagttc atgttgctga aggacaaaaa gttgcagcag
    20281 gagatctcct tgtcacagct gacttggatg ctatccgtgc agcaggacgt gaaacttcaa
    20341 cagtagttgt cttcacaaat ggtgatgcaa ttaaatcagt taaattagaa aaaacaggtt
    20401 ctcttgcagc taaaacagca gttgctaaag tagaattgta atatacttga ggttggaagc
    20461 tgtattccaa cctcttattt tgggagaaaa gaatgaaatt tttaacactc aatactcaca
    20521 gttggatgga gaaagaagca gaggaaaaat tccagatttt gcttgaagat attcttgaaa
    20581 aggactatga tttgatttgt ttccaagaaa tcaatcagga gatgacctcg tcagaggtgg
    20641 aggttaatga cctttatcaa gctttgccag cagctgagcc tattcaccaa gaccattatg
    20701 ttagactctt ggttgaaaag ttgttagagc aagggaaaaa ttactactgg acctgggctt
    20761 ataaccatat cggctataac cgctaccacg aaggtgtggc tatcttgtct aaaacaccta
    20821 ttgaagccag agaaattttg gtttcagatg tggatgatcc aacagactat catactcgcc
    20881 gtgttgccct agctgaaact gtagtcgatg gcaaggagct agcagttgcc agtgttcatc
    20941 tctcttggtg ggataaaggt ttccaagaag aatgggcacg atttgaggct gtcttgaaaa
    21001 aattgaacaa gccactttta ctagctggag attttaacaa cccagcaggt caggaaggtt
    21061 accaagctat tttagctagt ccattaggct tacaagacgc atttgaagtt gctcaagaga
    21121 aaagtggtag ctatactgtt ccgcctgaaa ttgatggctg gaaagggaac actgaacccc
    21181 ttcgaatcga ttatgtcttt actaccaaag agttagcggt ggaaaattta catgtcgtat
    21241 ttgatggtaa caagagtcca caagtgagtg atcactatgg cttgaatgct atgttaaact
    21301 ggaaataata actgaaaaga ggttggaact ataaaattcc agccttttct tactagagaa
    21361 gctactggaa atagcctaaa taagtgagac tactgtaatg gaataaaata tggtataatt
    21421 gataagatag atagaatcga ggatgttatg tcatttacga aatttcaatt taaaaactat
    21481 attagagaag ccttggagga gttaaaattt acaactccaa cagaggtgca agacaagttg
    21541 attcctattg ttttggcagg tcgtgaccta gtaggagaat caaaaacagg ttcaggtaag
    21601 actcatactt tcttgttacc gattttccag caattagatg aagctagcga tagtgtacaa
    21661 gcagtgatta ctgcaccgag tcgtgagttg gctactcaaa tttaccaagt agcgcgtcag
    21721 atttcagctc actcagatgt cgaagttcgt gtggttaatt atgtgggtgg tacggataag
    21781 gctcgccaga ttgagaaatt ggaaagcaat cagcctcata ttgttattgg aacaccaggc
    21841 cgtatctacg acttggttaa atctggtgat ttagctattc ataaagccaa gacatttgtt
    21901 gttgatgaag cagatatgac cttggatatg ggattcttgg aaattgttga taagattgct
    21961 ggcagtcttc caaaagactt gcaattcatg gtcttctcag cgactatccc acaaaaactg
    22021 caaccattct tgaaaaaata cttatcaaat cctgttatgg agaaaattaa gactaaaacg
    22081 gttatttctg acaccattga taattggttg atttcgacca agggacatga taggaatgct
    22141 caaatttacc aattgactca gttgatgcag ccgtatttgg caatgatttt tgttaacact
    22201 aaaacgcgtg ctgatgaatt gcattcatat ctgactgctc aaggcttgaa ggttgcaaaa
    22261 atccatggag atattgcccc tcgtgaacgc aagcgaatca tgaatcaggt gcaaaatctg
    22321 gattttgagt atattgtcgc aacagattta gcagcgcgtg ggattgacat tgaaggtgtc
    22381 agccatgtca tcaatgatgc cattccgcaa gacttatctt tttttgttca ccgtgttggt
    22441 cgtactggac gaaatggcct accaggtaca gctattaccc tttatcagcc aagtgatgac
    22501 tcggatatcc gtgagttgga gaaattggga atcaagttta gtcctaagat ggtcaaagat
    22561 ggggaatttc aagataccta tgaccgtgat cgtcgtgcca accgtgagaa aaaacaagat
    22621 aaacttgata tcgaaatgat tggtttggtt aaaaagaaaa agaaaaaagt caaaccgggt
    22681 tataagaaga aaattcaatg ggcggttgat gaaaagcgcc gtaaaactaa gcgtgctgaa
    22741 aatcgcgctc gcggtcgtgc agagcgtaaa gctaaacgcc aaacatttta atagaaattg
    22801 ttggagtact gagctccaac ttttttattt atgagaacga actatctaaa ccgaaacact
    22861 acattaaaga ctgcaaattg cgattaaaaa tggtataatg ataaagttat atagtcccga
    22921 taagatggta ggtatttatt acgaagagtt ttcctatcag tagattgcaa ttcgcaaaga
    22981 atgacggctt cgaggttgct cgtctttcta cggttgccgc catactgcgg tcaccctatg
    23041 cgccttacta gcttcagaaa taaaaaagta tcgtttttat ttctgaagct agtaactctt
    23101 agataatgga aattcctatc agtactttgt aactctataa caatattttt taagggggga
    23161 catttttatg tcagaacgta aattattcac gtctgaatct gtatctgagg ggcatccgga
    23221 taagattgca gaccaaattt cagatgcgat tttggatgct attttagcaa aggatccaga
    23281 ggcgcacgtt gctgctgaaa cagctgtata tactggttct gtccacgttt ttggtgaaat
    23341 ttctacaaat gcctatgtgg atattaaccg tgtggttcgt gataccattg cagagattgg
    23401 ttataccaat acagaatatg gattttctgc tgagacggtg ggagtacacc catctttggt
    23461 ggaacaatct cctgacatcg ctcaaggtgt taacgaagcc ttggaggttc gtggaaatgc
    23521 tgatcaagat ccactggact tgattggagc aggtgaccaa gggctcatgt ttggatttgc
    23581 agtagatgaa acagaagagc tcatgccatt gccaattgca ctcagtcata aattggttcg
    23641 tcgtctggca gaacttcgta agtctggaga aattagctat ctccgtccag atgcaaaatc
    23701 acaagttaca gttgagtacg atgaaaatga ccgtccggta cgtgtagata cagtcgttat
    23761 ttctactcag catgatccag aggccactaa tgaacaaatc catcaagatg tgattaacaa
    23821 ggtcatcaaa gaagttattc catcttctta tcttgatgat aagacaaaat tctttatcaa
    23881 tccgacaggt cgttttgtaa tcggtggtcc tcaaggggac tcaggtttga ctggtcgtaa
    23941 gattattgta gatacttatg gtggctactc tcgtcatggt ggtggtgcct tctctggtaa
    24001 agatgcgact aaggtggatc gttcagcctc ttatgcggct cgctatattg ccaagaatat
    24061 cgttgcagca ggccttgcta agaaggcaga agtgcagttg gcctatgcta tcggtgttgc
    24121 gcaacctgtt tctgttcgta tcgatacttt cggtacagga acagtagctg aaagtcaact
    24181 tgaaaaagcg gctcgtcaaa tctttgacct tcgccctgca gggattatcc aaatgctgga
    24241 cctcaagcgt ccaatttacc gtcaaacatc ggcttacggt cacatgggac gtacagatat
    24301 tgatcttcca tgggaacgtt tggataaggt agatgctttg aaagaagcag taaaataaga
    24361 ttttaagagg ggaacgtcct ctctttttta tagtttttaa ctatactggg atactgttct
    24421 gaaaatccat tttgcgaaag tagagattta catgtatagt agattgaaac tagaatagta
    24481 cacctcaact tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttctcctg
    24541 ttcttgtttc attttactat atttctttaa aaatgataaa ggttgagatt tctcctcgta
    24601 atagataatc atggggatat ttcaatccaa agttttattc gttatcactt gactattgca
    24661 aggttttcta gagcaacaga gtcatggaat ggactcatgg ttgagatttc tccttgttgc
    24721 ttggacttca ttcaaaagtc tgttacccaa gccttgttca aacttccaat acactagctg
    24781 tttccatagc atgacttctg tactagactt tcttttccga ataaatagat agaaccacag
    24841 aatctagtaa acctagaatt aaaattatgg tataatatta gcaataaaag aaatctggag
    24901 gattagaatc atggtatcaa cgaaaacaca aattgctggt tttgagtttg acaattgctt
    24961 gatgaatgca gcaggtgtgg cttgtatgac gatagaggag ttagaagagg tcaaaaactc
    25021 agcggcagga acctttgtta ctaagacagc gaccttggac ttccgtcagg ggaatcctga
    25081 gccacgctac caagatgttc cacttggttc catcaactct atgggcttgc caaataatgg
    25141 cttagactat tatttggatt atcttttaga tttgcaggaa aaagagtcga accgaacttt
    25201 cttcttatct ctggtcggca tgtctccaga ggaaacccat actattttga aaaaagtcca
    25261 agagagtgat tttcgtggtc tgactgagct aaatctttcc tgtccaaatg ttccaggtaa
    25321 acctcagatt gcctatgatt ttgagacaac agaccggatt ttggcagaag tgtttgctta
    25381 cttcaccaaa cctcttggaa ttaaattgcc accttatttt gatattgttc actttgacca
    25441 agcggcagct attttcaaca aatatccgct caagtttgtc aactgcgtta actctatcgg
    25501 aaacggcctc tatatagaag acgaatctgt cgttattcgg cctaagaatg gttttggtgg
    25561 aattggtgga gaatacatca aaccgactgc tctagccaat gttcacgcct tttatcaacg
    25621 tttaaatcct caaatccaaa ttatcggaac aggtggcgtt ctgactggtc gagatgcctt
    25681 tgaacacatc ctctgtggag caagtatggt gcaggtggga acgacccttc acaaagaagg
    25741 cgtcagtgct tttgaccgca ttaccaatga actgaaagca atcatggtgg aaaaaggcta
    25801 cgagagctta gaagatttcc gtgggaaatt gcgctatatt gactaaatta aatcgaaaaa
    25861 tcagaagaaa gaagggacga tgctagccat tgaagaaagt cagaagttga ctttatcaaa
    25921 tttaccgagc ctgagcctat ttacagggac agatcagggt cagtttgaag tgatgaagag
    25981 tcaaatgttg aaacagattg ggtatgattc tgctgacctc aactttgcct actttgatat
    26041 gaaagaagta gtttacaagg atgtggaact ggagttggtc agccttcctt tctttgcgga
    26101 tgagaaaatc gtgatattag attattttat ggatatcacg actgctaaga aacgcttttt
    26161 gacagatgat gagcttaagt catttgagga ataccttgac aatccttctc caacaaccaa
    26221 gttgataatc tttgcagaag gaaagctgga tagcaaaaga cggttagtca aattacttaa
    26281 gcgtgatgcc aaggtcttcg atgcagtaga agtaaaagaa caagaattgc gccagtattt
    26341 ccaaaagtgg agtcagaaac aaggtctgca gtttaccaat cattcttttg aaaatctcct
    26401 catcaagtcg gggtttcaat ttagcgaaat ccagaaaaat cttctctttt tacagtccta
    26461 taaggcgaat tctgttatcg aggaagagga tattgttaac gcaattccca agaccttgca
    26521 ggacaatatt tttgatttaa ctcagtttat tctgactaaa aagatggatc aggcgcgcga
    26581 tttagtgaga gacttgacct tgcaagggga agatgaaatc aaactgattg cagtcatgct
    26641 gggacaattt cggactttta ctcaggtgaa gattttggcg gagtctggcc aaacagaatc
    26701 gcagattgca agtagtttag gtagttatct gggacgtaac ccaaatcctt atcaaatcaa
    26761 gtttgcatta agagattcga gaggactttc tttgagcttt ctgaagcaag ctatttccta
    26821 tttgattgag acagactatc agattaagac aggtctttat gaaaaaggtt tcctttttga
    26881 aaaggcactc ttacagattg ctagtcaggt caattgacat ttgttgaaac tacaacccgc
    26941 gtcaggatta tcttgtcgtg ggtttcttgc tgatttgctt attttattag aaagtatatc
    27001 agtgatttcc ttatctataa gcaaaaaact tgaaaaaagt gaatgtttgc gttatcattt
    27061 tcatatagaa agaaaaagag gtattacaga tggctattat cttaccagaa cttccatatg
    27121 catacgacgc tttggaacca tacatcgatg cggaaacaat gcatttgcac catgacaaac
    27181 accatcaaac ttatgtcaac aatgccaatg cagctttaga aaaacaccct gaaatcggtg
    27241 aagaccttga agccttgctt gctgatgtag aatctatccc agctgatatc cgtcaagcac
    27301 ttatcaacaa tggtggcgga cacttgaacc acgctctttt ctgggaattg atgactcccg
    27361 agaaaacagc tccttcagca gaactggcag cagcaatcga tgcaacattt ggttcatttg
    27421 aagaattcca agcagccttc actgcagcag caacaactcg ttttggttca ggttgggcat
    27481 ggttggttgt caacaaagaa gggaaacttg aagtgacttc aacagcaaac caagacacac
    27541 caatctcaga aggtaaaaaa ccaatcttgg gcttggacgt ttgggaacat gcttactacg
    27601 tgaaataccg caacgtgcgt cctgactaca tcaaagcttt cttttcagta atcaactgga
    27661 ataaagtaga tgaattgtac gcagctgcta aataatgata gttggaggga agaattgttc
    27721 ttctcttttt taggttataa gattctggtc tgacaaaatc gtcagacttt tttcattttt
    27781 atgagaaacg tgctaactgc tagaaattat ggtagaataa agtattaagt aatcgtggaa
    27841 aaaggatatc tatgcgaaaa gaaattgcac ctgaattata caattataac aagtttcctg
    27901 gtccggagtt ccatttacac ggggacaagg tcgaaacgga agggatagct ttttccttgg
    27961 ttgaaaatat caaggatgcc tttgatgtga cgacttttaa tcagcgtttt tcagaagtct
    28021 taaccaagtt tgattatatc gtgggggact ggagcaacga acagcttcgc ctacgaggtt
    28081 tttacaagga tgaccgaaca gaagaaaaac ttgaaaaaat cagtcgttta caagactacc
    28141 ttttagagta ttgtagttat ggttgtgcct attttgtctt agaaaatgaa gcccctaagc
    28201 gagcatcatt tgacaagaaa atgcgtaaga cggaagaaga aacaccttct agaaaaggaa
    28261 agaaaccgac tcaaactaaa cgaaagtcga atgcagataa gaaaaataga cgtcgtcaga
    28321 aagaccagca ttctcagaaa gaggacaagg gacaacgtca ttttgtcatt cgtcagaagt
    28381 gagtagagaa taaggagaag aaatgaaacc ctcaattcat agtttggtac atcaaaccat
    28441 gcaggaatgg gtattggagc agggagaaaa gaaattccgt gcagatcaaa tctgggaatg
    28501 gctctaccgt aaacgtgtgc agtcatttga agaaatgacc aacctttcca aggatttgat
    28561 tgctaagctc aatgaccagt ttgtggtcaa tcccttgaaa caacgtattg tgcaagagtc
    28621 tgctgatggt acagtcaaat atctctttga attgcccgac ggtatgttaa ttgagactgt
    28681 actcatgcgt caacactatg gtttatctgt ctgtgtgacc actcaggtcg gctgtaatat
    28741 cggttgtacc ttctgtgcct ctggtttgat taagaagcag cgtgacctca ataacggtga
    28801 aatcgtagcg caaatcatgc tggttcagaa atactttgat gagcgtggtc aggatgaacg
    28861 catcagccat atcgttgtca tgggaatcgg tgagcccttt gataattaca acaatgtctt
    28921 gaatttcgtt tgtactatca atgatgataa aggaatggct atcggtgctc gtcacatcac
    28981 gatttcaacc tcaggtttgg ctcataaaat tcgtgacttt gctgatgaag gggttcaggt
    29041 caatcttgcc gtgtctcttc acgcacccaa caatgaactt cgttcaagta tcatgaaaat
    29101 taaccgtgcc tttccgattg aaaaactctt tgctgctatt gaatactata ttgagacaac
    29161 aaaccgtcgt gtaacctttg aatatatcat gcttaatgaa gtcaacgacg gtgtagaaca
    29221 agccttggaa ttggctgaat tgctcaagaa catcaagaaa ttgtcttatg taaacttgat
    29281 tccttataac ccagttagtg agcatgacca atatagccgt agtcccaaag agcgcgtgtt
    29341 ggctttctat gatacgctta agaaaaaagg ggtcaactgt gtggttcgtc aagagcatgg
    29401 tacagatatt gacgcagctt gtggacaatt gcgctctaac acaatgaaac gtgaccgcca
    29461 gaaggcagtc gcagcggtaa atccttaatg atgaagaaga cttataatca tattttggtc
    29521 tggggagtca ttttctatag catttgcatt gtctgttttt gctttactcc tcaagaacaa
    29581 tctaccgtgg gagtgggaac tccaggtatt cagcatcttg gacgcctggt ttttcttttg
    29641 actcctttca attctctctg gaaactgggc gaagtgagtg acattggaca attatgttgg
    29701 atttttttac aaaatatcct caatgtcttc ttgttttttc ctctgatttt ccaactcctt
    29761 tatctatttc caaatttgcg gaaaacaaaa aaggtccttc tttttagttt tcttgtgagt
    29821 cttggaatcg agtgtacgca attaatcttg gactttttct ttgatttcaa tcgcgtcttt
    29881 gagattgatg atttgtggac caacactttg ggtggctatc tggcttggct cctttataaa
    29941 cgattacata aaaacaaggt aaggaattaa aatgagtatt ttagaagtta aaaatctgag
    30001 tcacggtttt ggtgaccgtg caatttttga agatgtgtcc ttccgtctcc tcaagggaga
    30061 acatatcggc ctggtcggtg ccaatggtga aggaaaatca acctttatga gtatcgtgac
    30121 tggtaaaatg ctgccagatg aaggaaaggt tgagtggtcc aaatatgtga cggctggtta
    30181 cttggatcag cactctgtcc ttgctgaaag acagtcggtg cgtgatgttc tccgtacggc
    30241 ttttgatgag cttttcaaag ctgaagctcg tatcaatgac ctctatatga aaatggctga
    30301 agacggcgcg gatgttgatg ctctcatgga agaagtagga gaacttcaag accgtctgga
    30361 gagtcgtgat ttctatacct tggatgctaa gattgacgaa gtagcgcgtg ctcttggtgt
    30421 tatggacttt gggatggata cggatgtaac ttctttgtca ggtgggcaaa gaaccaaggt
    30481 gcttttggca aaacttctcc ttgaaaagcc tgatattttg ctgttggacg agccgaccaa
    30541 ctacttggat gctgagcata ttgattggct caagcgctat ctccaaaact atgagaatgc
    30601 ctttgttctt atttcgcacg atattccatt cctcaatgac gttattaata ttgtctatca
    30661 tgtggaaaat caacagctga cgcgttactc tggtgactac taccagttcc aagaagttta
    30721 tgctatgaag aaatctcagc tagaggcagc ctacgaacgc cagcagaaag agattgcaga
    30781 cctcaaggac tttgtggctc gtaataaagc ccgtgttgca actcgtaata tggctatgtc
    30841 tcgtcaaaag aaattggata agatggatat tatcgaactc caaagtgaga aaccaaaacc
    30901 atcctttgat ttcaaaccag ctcgtacacc agggcgcttt atcttccaag ccaagaactt
    30961 gcaaattggt tacgaccgtc ctcttactaa gcctttaaat cttaccttcg aacgcaatca
    31021 aaaggttgcg attattggtg ctaatggtat tggaaaaaca actctcttga agagtctctt
    31081 aggcattatc tcgccaatcg ctggggaagt ggagcgtgga gattatttag aacttggtta
    31141 ttttgagcag gaagtagaag gcggtaatcg ccaaactcct cttgaagctg tctggaatgc
    31201 ctttcctgcc cttaatcaag cagaagtccg tgcagccctt gcccgttgtg gtttgacaac
    31261 caaacatatt gaaagccaga ttcaagtatt atcaggggga gagcaagcca aggttcgttt
    31321 ctgtctcttg atgaatcgtg aaaacaacgt tttagtgctg gacgagccga ccaaccattt
    31381 ggatgtggat gcaaaggatg agctcaaacg cgctctcaaa gaatacaggg gatctatcct
    31441 tatggtctgc cacgagccag acttttatga aggttggata gaccaaatat gggattttaa
    31501 taatttaact taagaatgag agtaaaagaa atacagtacc gaatgtggat actgtatttt
    31561 tttggttttt aagatttaaa atcgtagtct ttcaccactt cgatgctgtc gattgtgata
    31621 gcagtagttg gcttgtcttt ttcatctttt tcggctttag caatcttatc cacaacatcc
    31681 ataccgtcaa tcacttgacc aaagactggg tgtttgccat ctagactagg gtttccacct
    31741 tctttgtagg cttcgataat tttctgtgga tacttgcttg tagggagttt agaagaggta
    31801 tctgtagagt tttggttgat gaagaactgg ctgccattgg tgtttggttg accagtatta
    31861 gccatagcaa gagcaccacg gatgttatac aaataaggag taatctcgtt cttgaaacca
    31921 gttcctttgt ctttagtctt atccttgtca tgccatatgg actgaccacc tgtaccgtcc
    31981 ccttttggat ctccagtttg gaccataaag ccatcgatga cacggtggaa ggtaataccg
    32041 ttatagtagc cttctttggc gtgagtgagg aaattttcaa ccgctagagg agcgagttta
    32101 gggaagagtt taatgcgaat atcaccttgg cttgtgtgga gaatcacttc ggcttcatct
    32161 tcagcaactt ccttagatag ttgtgggaaa ttggcgtttt cgtttgttaa agcatcgttt
    32221 aactccttgg cagattgggc agctactttg gaactttctt cagcagcaag actggaatca
    32281 acataatcat caccacgcag actgcgttgg acgctgctac acccagctag ggctacagta
    32341 gacagtaaaa gaagggttgc tagttttttc attctgatcc tctcaaaaat tcatttatac
    32401 cattgtaccc taaaaggaag tggatttcaa atattagtag tttacagaac tggcttagat
    32461 aatagttggg atttcatcat catcttgaaa atcttcaact tcttcaactt cttccccagt
    32521 aaatggtttc tgaaaagaac ttagtataaa acgggcaatt ggttcaacaa ttaggaaatt
    32581 tagaggaaga gctgcaataa agtttacgaa ccaggcgctt agataggtat tgggtgtgat
    32641 agcaatgcca ttgtaaaaaa gtccatagaa ggacatgaaa gtgaccagct aattcttctt
    32701 ctgaaaaatg ctcatgaagg gcttgatcca ggtcgcaaga tttcatttta gaaagtccag
    32761 taactccctt cttcttcagg atattctttt tcatggtatt atttagatgg tcaagtgagt
    32821 caaaagaagt ttcgacaaga gcataccctt tttctaccag agtttttaga tgtttagggg
    32881 catcaatacc ataagtgtac tcaaagtatt ttggaaacca gatcttaaga aagctcgtaa
    32941 agctagccag ttctctaaac gctaagaact agctacaaca cagcatttac aacacttcat
    33001 ggttcacacc atggggtgtt ttttaatgat tttaagcaaa attcacactt aattgaaagt
    33061 tatttaaatt agatgaaaat ttattttttg aaaaagtggg aaaacattga ttctaagcga
    33121 attttgaatc atattcgaat gggagttttt aaaatcatgt ttcagtggta aaagtaccaa
    33181 actggattct ccatagtaaa atgatatctc ctgctagtga atcatctgct aataagtcca
    33241 tatttcgctt gggacttaga agccaagtat ccaactctcg ttcaggcgat atgaagggtt
    33301 tgacttggtg ttctttataa aatttttcta aaatagtatt cacggatagc atctttcaaa
    33361 catttatttc ctattctaac aaatttctaa atgctttaag aaatttatag tctgtcaagt
    33421 ttttttcttg acacctgcca gaaatctgct ataatagaac atgtgctaaa tagctcagct
    33481 atttcaccga aataaaaaat taaagaaatg agactttaaa aatggcagtt aaaatccgtt
    33541 tgactcgtat gggttctaag aaaaaacctt tctaccgtat caacgtagca gattcacgtt
    33601 caccacgtga cggacgtttc atcgaaacag ttggaactta caacccactt gttgctgaaa
    33661 accaagtaac tttgaaagaa gaccgcgttc ttgcatggtt ggctaatgga gctcaacctt
    33721 cagacacagt acgtaacatc ctttcaaaag aaggcgtatt gaaaaaattc cacgattcta
    33781 aattctcaaa ataagtttaa agtaggttga cagatggata cgattgaaaa tctcattatt
    33841 gcgattgtga aacccttaat ttcacaacca gatgccttaa ctatcaagat tgaggataca
    33901 ccagaatttt tggaatatca tttgaatctt gatcaaagcg atgtgggtcg tgtaatcggt
    33961 cgtaagggtc gcactatttc tgcgataaga acgattgtct actctgtccc aactgaatac
    34021 aaaaaagtaa gaatcgttat tgacgaaaaa taagaagggc gggacggatg tctcgctttt
    34081 ttgtgtggaa tagaagatat agtaaaatga aataataaca ggacaaatcg atcaggacag
    34141 tcaaatcgat ttctaacaat gttttagaag taaaggtgta ctattctagt ttcaatatac
    34201 tataaaagat tgaacgttta ggcaattcca agactactta atcgaacatt aacagcagtc
    34261 tcggactgat gaaggtcttt ttatgaagtt agtggaggaa gtcggagaag tagccgaggt
    34321 tttgaatagg cgctctggtc gaaaagaagg gataggattc gaacgaggaa cttgccagag
    34381 aactggctga tatcatttac tacaccgtcg caatcgtagc tattaatcat attgacctta
    34441 ccaagactgt ctttgagaaa gacaaaaccg cagccgttaa ttaccaacat aaacataatt
    34501 tggaaggatt attgaaggga aagtagagat attgtcccct tcctccaact tgagaaaatc
    34561 cttggaacgt gataaaataa aggataagga tttttaataa ttcattatat agaatcagtg
    34621 gatttcttta tgaagaggtt tgaagtatct acagaaattg gtagcctctc tgttacttat
    34681 caaaagcaaa agaaagtgct agtttgtcta aacggagcag gtttgctacc aagttatgaa
    34741 aatttttcac ttatacttga aaaacctcct cctacaattg gttatttgac aattgatttt
    34801 ccgaacacag gtaggagtcc gattcatgac caagctggaa aaaatctaga taatcttgca
    34861 gatgcggttt atgaagtact tgaagaatta ggaatttctg aatatatact ttgtgcacat
    34921 agttggagtg gaattttagc ttgcaaatta ctcgagaaac caattaagcg tcagacttta
    34981 gtagcaattg aaccgacaac taaaaaagtc atgtttgctg atttttcaga aaatccttat
    35041 ccagaaatgg aagagcagat gaggctgatt gacgagtgtg gtcctgaact ttattttaag
    35101 aacttaactc aagcaacatt tagtcctgaa acgaataaaa aaatctggga attaatgcaa
    35161 gaaaaaggct tagagttgga aaatcaagat ccagaatttc agatatctgg agagattact
    35221 gaggaagatt ttgaggatgt atctatagaa gctcatattc ctgtatttgt tttttgtcag
    35281 ccttatagag aaaaagagta cagagaatca gaatattgga cttccaatac taaactcatt
    35341 ttaggaggga atcaccatta tttacaatgg tcagaatcgg aaaaaattgc ggctattatt
    35401 cgagaattgt tagaataaga tggaaaaaag gagattacag gagacaagat gaactacttt
    35461 aatgttggga aaatcgttaa tacgcaggga ttacagggtg agatgcgagt cttgtctgtg
    35521 acggattttg cagaagaacg gtttaaaaaa ggagctgagc tggctttgtt tgatgaaaaa
    35581 gatcagtttg tccaaacagt gaccatcgct agccaccgta aacagaagaa ctttgacatt
    35641 attaaattca aagatatgta ccatatcaat actatcgaaa agtacaaggg atacagtctc
    35701 aaggtcgctg aggaagattt gaatgaccta gacgatggtg aattttacta tcacgagatt
    35761 atcggtttgg aagtctatga gggtgatagc ttggttggaa ccatcaagga aatcctgcaa
    35821 ccaggtgcta atgatgtctg ggtggtcaaa cgaaaaggca aacgtgattt gcttttacct
    35881 tatatcccac cagtggttct caatgttgat attccaaata aacgggtcga tgtggaaatc
    35941 ttagaagggt tagacgatga agattgatat tttaaccctc tttccagaga tgttttctcc
    36001 actggagcac tcaatcgttg gaaaggctcg agaaaaaggg ctcttggata tccagtatca
    36061 taattttcga gaaaatgctg aaaaggcccg tcatgtagat gatgagccct acggaggcgg
    36121 tcagggcatg ttgctcagag tacaacctat tttcgattcc tttgatgcta ttgaaaagaa
    36181 aaatccgcgc gttattctcc tcgatcctgc tggaaagcag tttgatcagg cttatgctga
    36241 agatttggct caagaggaag agctaatctt tatctgtggg cactatgagg gttatgatga
    36301 gcgcattaag accttggtaa cagatgagat ttccctaggc gactatgtcc tcactggtgg
    36361 agaattggca gctatgacca tgattgatgc tacagttcgc ctgattccag aagtgattgg
    36421 caaggagtct agccaccaag atgatagttt ttcttcaggt cttttagaat atcctcagta
    36481 cacacgtcct tatgattatc gaggcatggt cgtgccagat gtattgatga gtggccacca
    36541 tgaaaagatt cgtcagtggc gattgtacga gagtttaaag aaaacctacg agcgcagacc
    36601 ggatttactt gaacattatc aactgacagt agaagaagaa aaaatgctgg cagaaatcaa
    36661 agaaaacaaa gaataaagga gaaacctatg caagtaatca aacgtaatgg cgaaattgct
    36721 gaatttaatc cagataagat ttaccaagcc atcttgaagg cagcccaaac tgtttatgtt
    36781 ttgacagatg atttgcgtca aaatcttgct caagtcacta agaaggtagt tttggattta
    36841 caagaagcca aggtggaacg tgcgactatc agtatgattc aatctatggt tgaacatcgt
    36901 ttattgggcg caggttacat taccattgca gaacactaca tttcctatcg tttacaacgt
    36961 gacttggaaa gaagtggtta tggagatcat atcgcagttc atttacattt tgaacaaatt
    37021 cgctaagaaa aaagagtggg atgaagcaac tacatctcac tctttcttaa atctattttt
    37081 ttgggctgtt tggacagttg aggggacaaa tcgcaggcgt tgaatatcgc ttatacggat
    37141 aatccggctc acatttttgg aaaaattttt cacgataatt tgctggcctt gctgatcata
    37201 tttgatgatg tcacctgtaa agcttgtctc agataagata aggtgaacag cggtttgttt
    37261 ctggatagcc tcttcaatag tggctgtaag ggagttggtt tcagtctggt caggttggtc
    37321 atatccattt aaaaaatcat gtattttatt tagaacttgc tggaatttat gtctcatatt
    37381 ggcctccctt cttttatatc aatattatat aaaattttcc taaaatctac aagattttac
    37441 gaataaacta atgaaactaa aaaaggagaa gaaaatggca gaatttacat ttgaaatcga
    37501 agagcacttg ttgactcttt ctgaaaacga aaaaggttgg accaaggaaa ttaaccgtgt
    37561 gagctttaat ggtgcccctg caaagtttga tattcgtgct tggagtccag accatactaa
    37621 aatgggcaaa gggattactc tctcaaatga agaatttcaa acgatggtgg atgcctttaa
    37681 aggcaactaa tactcttcga aaatctcttc aaaccgcgtc agctttgcct tgccgtatgt
    37741 atggttactg acttcgtcag tttc
//
LOCUS       DAVLHM010000021        35954 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLHM010000021 DAVLHM010000000
VERSION     DAVLHM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.021"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            100..597
                     /locus_tag="VXE45_001100"
     CDS             100..597
                     /locus_tag="VXE45_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0789142.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            597..2252
                     /gene="dnaX"
                     /locus_tag="VXE45_001101"
     CDS             597..2252
                     /gene="dnaX"
                     /locus_tag="VXE45_001101"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0789143.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATDKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2280..2474
                     /locus_tag="VXE45_001102"
     CDS             2280..2474
                     /locus_tag="VXE45_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0789144.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2624..3394
                     /gene="sufC"
                     /locus_tag="VXE45_001103"
     CDS             2624..3394
                     /gene="sufC"
                     /locus_tag="VXE45_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0789145.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3422..4684
                     /gene="sufD"
                     /locus_tag="VXE45_001104"
     CDS             3422..4684
                     /gene="sufD"
                     /locus_tag="VXE45_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0789146.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4695..5921
                     /locus_tag="VXE45_001105"
     CDS             4695..5921
                     /locus_tag="VXE45_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0789147.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATAFYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5908..6348
                     /locus_tag="VXE45_001106"
     CDS             5908..6348
                     /locus_tag="VXE45_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0789148.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6402..7814
                     /gene="sufB"
                     /locus_tag="VXE45_001107"
     CDS             6402..7814
                     /gene="sufB"
                     /locus_tag="VXE45_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0789149.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8045..9286)
                     /locus_tag="VXE45_001108"
     CDS             complement(8045..9286)
                     /locus_tag="VXE45_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0789150.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9389..10498
                     /locus_tag="VXE45_001109"
     CDS             9389..10498
                     /locus_tag="VXE45_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0789151.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11032..11379
                     /gene="ssrA"
                     /locus_tag="VXE45_001110"
     tmRNA           11032..11379
                     /gene="ssrA"
                     /locus_tag="VXE45_001110"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11552..11639)
                     /locus_tag="VXE45_001111"
     tRNA            complement(11552..11639)
                     /locus_tag="VXE45_001111"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11603..11605),aa:Ser,seq:gga)
     gene            11802..12542
                     /locus_tag="VXE45_001112"
     CDS             11802..12542
                     /locus_tag="VXE45_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0789152.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12539..13450
                     /gene="pfkB"
                     /locus_tag="VXE45_001113"
     CDS             12539..13450
                     /gene="pfkB"
                     /locus_tag="VXE45_001113"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0789153.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13447..15399
                     /locus_tag="VXE45_001114"
     CDS             13447..15399
                     /locus_tag="VXE45_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0789154.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15563..17788
                     /locus_tag="VXE45_001115"
     CDS             15563..17788
                     /locus_tag="VXE45_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0789155.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKTLLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17833..18261)
                     /locus_tag="VXE45_001116"
     CDS             complement(17833..18261)
                     /locus_tag="VXE45_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789156.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18399..19541
                     /locus_tag="VXE45_001117"
     CDS             18399..19541
                     /locus_tag="VXE45_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0789157.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19550..20764
                     /gene="thiI"
                     /locus_tag="VXE45_001118"
     CDS             19550..20764
                     /gene="thiI"
                     /locus_tag="VXE45_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0789158.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20899..21722
                     /locus_tag="VXE45_001119"
                     /pseudo
     CDS             20899..21722
                     /locus_tag="VXE45_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            21744..22483
                     /locus_tag="VXE45_001120"
                     /pseudo
     CDS             21744..22483
                     /locus_tag="VXE45_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22496..23662
                     /locus_tag="VXE45_001121"
     CDS             22496..23662
                     /locus_tag="VXE45_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0789159.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            24170..25663
                     /locus_tag="VXE45_001122"
     CDS             24170..25663
                     /locus_tag="VXE45_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0789160.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25676..26797
                     /locus_tag="VXE45_001123"
     CDS             25676..26797
                     /locus_tag="VXE45_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0789161.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            26857..27093
                     /locus_tag="VXE45_001124"
     CDS             26857..27093
                     /locus_tag="VXE45_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0789162.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            27090..27503
                     /locus_tag="VXE45_001125"
     CDS             27090..27503
                     /locus_tag="VXE45_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0789163.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27621..28586
                     /locus_tag="VXE45_001126"
     CDS             27621..28586
                     /locus_tag="VXE45_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0789164.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            28610..29136
                     /locus_tag="VXE45_001127"
                     /pseudo
     CDS             28610..29136
                     /locus_tag="VXE45_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466610.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            29166..32516
                     /locus_tag="VXE45_001128"
     CDS             29166..32516
                     /locus_tag="VXE45_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0789165.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFGENCCVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIEEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            32787..32864
                     /locus_tag="VXE45_001129"
                     /pseudo
     CDS             32787..32864
                     /locus_tag="VXE45_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(33102..33572)
                     /locus_tag="VXE45_001130"
     CDS             complement(33102..33572)
                     /locus_tag="VXE45_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0789166.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(33589..35862)
                     /locus_tag="VXE45_001131"
     CDS             complement(33589..35862)
                     /locus_tag="VXE45_001131"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0789167.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT        10975 a         6432 c         7800 g        10747 t
ORIGIN      
        1 ggggttaccc actacaaata ttatagagcc caaaatcctt tgtttactaa acaagggatt
       61 tttcttttgt ctctgctcct tttttgatat aatagttcta tgttaaaatc agaaaaacaa
      121 tcacgttatc aaatgttaaa tgaagaattg tccttcctat tggaaggcga aaccaatgtt
      181 ttggctaatc tttccaacgc cagtgctctc ataaaatcac gttttcctaa taccgtattt
      241 gcaggctttt atttgttcga tggaaaggaa ttggttttag gccccttcca aggaggtgtt
      301 tcctgcatcc gtattgcact aggcaagggt gtttgtggtg aggcagctca ctttcaggaa
      361 actgttattg ttggagatgt gacgacctat ctcaactata tttcttgtga tagtctagct
      421 aaaagtgaaa ttgtggtgcc gatgatgaag aatggtcagt tacttggagt tctggatctg
      481 gattcttcag agattgagga ttacgatgct atggatcgag attatttgga acaatttgtc
      541 gctattttgc ttgaaaagac aacatgggac tttacgatgt ttgaggaaaa atcttaatgt
      601 atcaagcact ttatcgaaaa tatagaagtc aaaacttctc ccagttagtt ggtcaagaag
      661 ttgtggctaa gactcttaaa caagcggtgg agcaagagaa aataagtcac gcttatcttt
      721 tttctggtcc tcgtggaacg ggaaaaacca gtgttgctaa aatctttgcc aaggctatga
      781 actgtcccaa tcaagtgggt ggcgaacctt gcaataactg ctatatttgt caagcagtga
      841 cggacggtag tttagaagat gtcattgaaa tggatgcagc ttctaataat ggggtagatg
      901 aaattcgcga aattcgtgat aaatctacct atgcgcctag ccttgctcgt tataaggttt
      961 atatcataga tgaggttcac atgctgtcta caggggcttt taatgccctc ctaaagacgc
     1021 tggaagaacc aacacagaat gtagtcttta ttttggccac tactgaattg cacaagattc
     1081 ctgctactat tctatcccgt gtgcaacgtt ttgagtttaa atcaattaag acacaggata
     1141 ttaaggaaca tattcactat atcttagaaa aagaaaatat cagttctgaa ccagaggctg
     1201 tggaaatcat tgccagacgg gcggaaggtg gaatgcggga cgccttgtct attttggatc
     1261 aagccctgag tttgacacag ggaaatgagc tgacgactgc tatctctgaa gaaattactg
     1321 gcaccattag cctatcagcc ttggatgatt atgtggcggc cttgtctcaa caggatgttc
     1381 ccaaagcttt gtcttgcttg aatcttcttt ttgacaatgg taagagcatg actcgttttg
     1441 tgaccgatct tttgcactat ttaagagact tgttaattgt tcaaacaggg ggagaaaata
     1501 ctcatcatag ttcagtcttt gtagaaaatt tggcacttcc tcaaaaaaat ctgtttgaaa
     1561 tgattcgctt agcaacagtg agtttagcag atattaagtc tagtttgcag cccaagattt
     1621 atgctgaaat gatgaccgtc cgtttggcgg aaatcaagcc cgaaccagct ctatcaggag
     1681 cggttgaaaa tgaaattgct acgctgagac aggaagttgc ccgtctcaaa caagagcttt
     1741 ctaatgtagg tgcggttcct aaacaagttg caccagctcc tagtcgacca gctacggaca
     1801 aaacagtcta tcgtgtcgat cgcaataaag tgcaatctat cttacaagag gccgtcgaaa
     1861 atcctgattt agcacgtcaa aatctaattc gtttgcagaa tgcctgggga gaggtaattg
     1921 aaagtctagg tgggccggac aaggctctgc tagttggttc tcaaccggtt gctgccaatg
     1981 aacaccatgc tattcttgct tttgagtcta acttcaatgc tggtcaaact atgaaacgag
     2041 acaatctcaa taccatgttt ggtaatatcc tcagtcaggc ggcaggtttt tcacctgaga
     2101 ttttagctat ttccatggag gaatggaaag aagttcgcgc agccttttca gccaaagcca
     2161 aatcttctca aactgaaaaa gaagtagaag aaagcctgat tccagaagga tttgaatttt
     2221 tggctgataa agtgaaggta gaggaagact aaagaaagat ttcatgatac aataagttta
     2281 tgaataaaca acaatttatt attatggcgc tgtttacagc tgctgagacc tattttttca
     2341 atgaagcctg gatgactggc cgctatatta tggcagcctt ttgggcaatt ttactcttta
     2401 gaaatttccg agtcagttat gtgatgggca aaatcgttga tgtcatcgat cagcatttta
     2461 ataggaaaga ctagccctca gcttccagac aaaatcaaag ccttttaggc ttttttttgt
     2521 tatactagaa aagtatattt atagaatttt tgctctattt ctggggaaat cagacgtttt
     2581 tctagtaagt actgtaaaag ttttgaaaaa gaaaggaact atcatgtcag tattagagat
     2641 taaagatctt cacgttgaga ttgaaggaaa agaaatttta aaaggggtta acctgaccct
     2701 gaaaacagga gaaattgccg ctatcatggg accaaatggt acaggtaaat cgactctttc
     2761 tgccgctatc atgggaaatc caaactatga agtaactaaa ggtgaagttt tgtttgatgg
     2821 cgtaaacatc cttgagttgg aagtggatga gcgtgcgcgt atgggacttt tccttgctat
     2881 gcaataccca tcagaaatcc ctggaattac caatgctgag tttcttcgtg ccgctatgaa
     2941 tgcgggtaaa gaagatgatg agaagatttc agttcgtgag tttattacta agctagatga
     3001 aaaaatggaa ttgctcaaca tgaaagaaga aatggcagag cgttacctca acgaaggctt
     3061 ctctggtggt gagaaaaaac gcaatgaaat tcttcaactt ttgatgttgg agccaacatt
     3121 tgctcttttg gacgagattg actcaggtct tgatattgac gctcttaaag ttgtgtctaa
     3181 aggtgtcaat gccatgcgtg gtgaaggttt tggtgctatg atcatcactc actaccaacg
     3241 tcttttgaac tatatcacac ctgatgtggt acacgtgatg atggaaggtc gtgttgtcct
     3301 ttctggtggt ccagaattgg ctgcgcgttt ggaacgtgaa ggatacgcaa aattagctga
     3361 agaacttggc tacgactaca aggaagaatt gtaatttcct cgtatctttt aggagaagta
     3421 aatgactaga gaaaatatta aacttttttc agaaatgcac gctgaaccaa gctggttggc
     3481 tgatctccgt caaaaagctt ttgacaagat tgagactttg gaattaccag ttattgagcg
     3541 tgtcaaattc caccgttgga atctgggtga tggaacgatt acagaaaatg agccatcagc
     3601 aaatgttcca gatttcacag ctttagatca tcacttgaag ttggtgcaag taggaactca
     3661 aactgttttc gaacaaactc cagttgagtt agctgaacag ggtgttgtct tcacagactt
     3721 tcactcagct ttagaagaaa ttccagagct gatcgaagaa ttcttcatgt catctgttaa
     3781 gtatgatgat gacaagttgg cggcttacca cacagcttac tttaacagtg gtgctgtact
     3841 ctatattcca gataacgtag aaatcacaga gccaattgaa ggaattttct accaagatag
     3901 cgatagcaat gtgccgttta acaagcatat tatgattatc gctggtaaaa attctaagat
     3961 tagttatctg gagcgtttag agtcacgcgg tgaaggaagt gacaaagtaa ctgccaatat
     4021 cacagtggaa gtgattgcac gttctggtgc gcaagtcaag tttgctgcta tcgaccgtct
     4081 aggtgaaaac gtcactgcct acattagccg tcgtggtaaa ttaggcaacg atgcaagtat
     4141 tgactgggct atcggtgtca tgaacgaagg aaatgtcgtt gctgattttg atagtgactt
     4201 gattggtaat ggtagccatg ctgacctcaa ggttgtagct ctttcaagtg gtcgtcaggt
     4261 acaagggatt gatactcgtg taactaacta tggctgcaac tctatcggaa atatcctaca
     4321 acatggggtt atccttgaaa aagcaacttt gactttcaat ggtatcggcc acatcatcaa
     4381 gggtgctaag ggagcagatg cgcaacaaga gagccgtgtt ctcatgcttt cagaccaagc
     4441 gcgttcagat gctaacccaa ttcttttgat tgatgaaaat gatgtcactg caggacacgc
     4501 agcgtctatc ggacaagttg atccagaaga catgtattac ctcatgagtc gtggattgga
     4561 taaggcaact gcagagcgtt tggttgttcg tggtttcctt ggatctgtta tcgtggagat
     4621 tccagtcaag gaagttcgtg atgaaatgat tgcaactatc gaagagaaat tgtcaaaacg
     4681 ctaaggggaa gcctatgtta gatgtagaag cgattcgcaa ggattttcca attttagatc
     4741 agattgtcaa tgatgaacct ctggtctatc tggacaatgc tgcgacgaca caaaaacccc
     4801 tagtagttct gaaagctatt aacagttact atgagcagga caatgccaat gttcaccgtg
     4861 gtgtccatac cttagcggaa cgagcgacag ctttttatga agctgctcgt gaaaccattc
     4921 gtaagtttat taatgcaggc tctacaaagg aagttctctt taccagagga acgacaacca
     4981 gccttaactg ggtggcacgc tttgctgagg aaattctcac tgagggagac caggtcttga
     5041 tttcagtaat ggaacaccat tctaatatca ttccatggca ggaagcttgt cgaaagactg
     5101 gagcagagct tgtctatgtc tatcttaaag acggtgcctt ggatatggag gatttgcgag
     5161 ctaaattgac tgataaggtt aaatttgttt ccctagctca tgcctccaat gttcttggtg
     5221 tgatcaatcc gatcaaggaa atcactcaat tagcccacca agttggggca atcatggtag
     5281 tggatggtgc tcaatctaca cctcatatga agattgatgt ccaggacttg gatctggact
     5341 ttttcgcctt ttcgggtcac aagatggctg gtccgactgg tatcggtgtc ctttacggca
     5401 aagaaaagta tcttgagcaa atgtctccag tagaatttgg cggcgagatg attgattttg
     5461 tctacgagca atttgctagt tggaaggaat tgccttggaa atttgaggct ggaacgccaa
     5521 atatggcagg agctattgga cttgcgactg cagttgatta tttggaaaag attggtatgg
     5581 atgccgttga agctcatgaa caggaattga ttgcgtacgt ctatccaaaa ctgcaggcaa
     5641 ttgagggatt gaccatttac ggttctcagg atttggctca acgttcgggt gttattgcct
     5701 ttaacctagg tgatctccat cctcacgatc ttgcgacggc tctggattat gaaggagtgg
     5761 ctgttcgtgc tggtcaccat tgtgcgcaac ccttgcttca gtatttggaa gtcccagcaa
     5821 cagctcgtgc aagtttttat atctacaata ccaaggcaga ttgcgacaaa ctagtcgatg
     5881 ccctacaaaa gacaaaggag tttttcaatg gcactttcta aactagatag cctttatatg
     5941 gcagtggtag cagaccattc gaaaaatcca catcaccaag ggaagttaga agatgctgag
     6001 caaatcagtc tcaacaatcc gacttgtggg gatgtcatca acctctctgt caagtttgat
     6061 gcagaggacc gtttggaaga tattgctttt ctaaattcag gatgcacgat ttcaactgct
     6121 tctgctagta tgatgacaga tgccgtttta ggaaaaacca aacaagaaat tttagaactg
     6181 gcgactattt tttctgaaat ggttcaaggg caaaaagatg agcgtcaagg ccaacttgga
     6241 gacgcggcat tcttgtcagg tgttgccaaa ttccctcaaa gaatcaagtg tgcaacccta
     6301 gcttggaatg cccttaagaa aacaattgaa aatcaagaaa aacagtaaga caagtttctt
     6361 ttgtcttatg aattattaga aatgaagaaa gaaaggatac tatggctgaa gaaagagtag
     6421 aaccaaaacc aattgacctt ggtgaatata aatttggttt ccatgacgat gtagagcctg
     6481 tcttatcgac aggaaaagga ctcaacgaag gtgttattcg tgaattatct gctgctaagg
     6541 gtgagcctga gtggatgttg gagttccgtt tgaagtctta tgaaaccttc aaaaaaatgc
     6601 ccatgcaaac ttggggagca gacttgtcag agattgactt tgatgactta atctactacc
     6661 aaaaaccatc tgacaaacca gcccgttctt gggatgatgt acctgaaaag attaaagaaa
     6721 cctttgaacg tatcgggatt ccagaagctg aacgtgctta tttagcaggg gcttctgccc
     6781 agtacgagtc agaagtggtt taccacaaca tgaaggaaga gttccaaaaa ttaggtatta
     6841 tctttacaga tacagattcc gcactcaagg aatacccaga cttatttaaa caatactttg
     6901 cgaagttggt accgccgaca gataacaagt tggcagccct caactcagca gtatggtcgg
     6961 gtggaacttt tatctacgtg ccaaaaggtg tcaaggtaga tattccactt caaacttatt
     7021 tccgtatcaa taacgaaaat ataggtcagt tcgaacgtac cttgattatc gttgatgagg
     7081 gagcaagcgt ccactacgta gaaggatgta cagcaccaac atattcaagc aatagcttac
     7141 acgctgccat tgtagaaatt tttgctttgg acggagctta tatgcgttat acaactatcc
     7201 aaaactggtc tgataacgtc tataacttgg taacaaagcg tgctaaggct caaaaggatg
     7261 ccactgttga gtggattgat ggaaacttgg gtgccaaaac gactatgaaa tatccatctg
     7321 tttaccttga tggagaagga gcgcgtggta ccatgctctc tatcgccttt gctaatgcag
     7381 ggcaacacca agacacgggt gctaagatga ttcacaatgc tccacatacc agctcgtcta
     7441 ttgtgtctaa atccatcgct aaaggtggag gaaaggttga ctaccgtgga caagtcacct
     7501 ttaacaagaa ctctaagaaa tctgtttccc acattgaatg tgataccatt atcatggatg
     7561 acttgtcagc atcagatact attccattta atgaaattca caactcgcaa gtggctttgg
     7621 aacacgaagc caaagtatct aagatttcag aagagcaatt gtattatctc atgagccgtg
     7681 gattgtcaga atctgaggca actgaaatga ttgtcatggg atttgtagaa ccctttacaa
     7741 aagaacttcc aatggaatac gcagttgagc tgaaccgctt gattagctat gaaatggagg
     7801 gatcagttgg ataaaatttg attttatact cttcgaaaat ctcttcaaac cacgtcagca
     7861 tcgccttacc gtatgtatgg ttactgactt cgtcagtttc atctacaacc tcaaaacagt
     7921 gttttgagca agctgcggct agcttcctag tttgttcttt gattttgagt attagattta
     7981 ctcaaaatca aggattttga agatgaactt gtatcaaaaa atcgcggttt aaaatcgcga
     8041 ttttttataa tttctcgtta acaaagcgga caaactgatt ccaccaaact tttaagaaga
     8101 aggctttttc aattttcttg tctgctacca tttcgaaact agggcgctct gtggtgatgt
     8161 aaccttgacc aatcaagtcc ttgtcttcat aagtcaaatg gccaaccact gttccagctt
     8221 caagtggtgc tgggattgct ttggaatcag gtgtgaattg aacagattgg gaagattgat
     8281 tcccaacacg ttcgattaga tagatatcct ctggagccac tgcagttact gtatcttctt
     8341 ttccatcttg tacaggggtt ttgctatctt gataggcatc gccttgttga acgattttgc
     8401 gaagtgtaaa tgtagaagaa atataatcca ttagggaaga tgtagctgta aatcgagcgt
     8461 aaggattatt gtcttgatga tctgcattta aaacaactgt gatgactctc atgccttttt
     8521 cgacagtagt accaacaaaa gactctccag ccttatctgt tgttcctgtt tttagcccat
     8581 caaaaccacc acggtaagca ggcatacctt ctaacatgta gttggttgaa gtgattgtca
     8641 tcccagcaaa agtagaagaa ggttttttgg tgatttctaa gacttgtggg tattttttga
     8701 tgaggttgcg agcaacgata gcgacatcat aagcactaag cttattttcc tcatcttttt
     8761 tagaacctgg gtaaatgtta tcccctagag tttcattgtt aagacctgtc gtattgacaa
     8821 cagtggcatc ctgaattccc cattccaaga gttttgcccg catcatatcg acgaaatctt
     8881 tttctgagcc agcaattttc tcagctaggg caatagcggc gctgttggca ctagatacca
     8941 gagttgcttc aagcaactct tcgacagtat aattacgggc ctccatagga atattactgg
     9001 cttcagaatt tgtcgtcaat tgataaggat aatcagaaat atctacagga gtggagaggg
     9061 taatacttcc gttttccaaa gcttcataga ccagataaac agtaatcaat tttgttatgg
     9121 aagcaatttc gacaggttgc gttgcatcct tctcatagag aattttacca gtatttgcct
     9181 caacagcaat cgcatgttta gcggcaatgg taaaatcttg agcaacagca gtagaagcac
     9241 cccctaaaag agagacagtt aacaaagtta aaaatatttt tttcatagta gtcttattct
     9301 atcataaaga aaaaaaatat tcttgcttta ataattcatc tgttaagctt tttgaaaata
     9361 tggtaaaata aagtgaggga ggtaactcat gtttcgtaga aataaattat ttttttggac
     9421 cacagaaatt ttactcttaa ccatcatctt ttacctatgg agacagatgg gatctttgat
     9481 taaccctttt gttagcgtgc ttaatacaat tatgattcca tttttattag ggggctttct
     9541 ttattatttg acaaacccta ttgttacttt cttaaataaa gtctgtaaac tcaatcgttt
     9601 gcttggtatt ttaattacct tgtgtacttt ggtctgggga atggtcatag gtgttgtcta
     9661 tctcttacct attttgatta atcagttatc tagtttgatt atatctagtc aaactattta
     9721 tagtcgagta caagacttaa tcatagactt atctaattat cctgcgctcc agaatttgga
     9781 tgtagaagct acaattcagc agttaaactt atcctatgtt gatattcttc aaaatatcct
     9841 aaatagcgta tcaaatagtg tggggagcgt cttgtcagct cttatcagta ctgttttgat
     9901 tttgattatg actccagttt ttttggttta tttcttatta gatggacata aattcttgcc
     9961 catgcttgaa agaacgattc taaagaggga tcgcttgcat attgcaggct tattaaagaa
    10021 tttaaatgcg acgattgctc gctatattag tggagtttcg attgacgcaa tcattatagg
    10081 ttgtttggct tatattggct atagtattat tggtttaaaa tatgctttag tttttgccat
    10141 tttttctggt gtagccaatt taattcctta tgtggggcca agtattggtt tgattcctat
    10201 gatcatcgca aatatattca ctgatcccca tagactgctg attgcagtga tttatatgct
    10261 tgttgttcag caggtagatg gcaatatctt atatcctcga atcgtaggaa gtgttatgaa
    10321 ggttcatcca atcacgattt tagttttact tttgttgtca agcaatatct atggtgtagt
    10381 tggaatgatt gtcgcagtgc caacctattc tatcttgaaa gaaatttcta agttcttatc
    10441 ccgtttgtat gaaaatcata aaataatgaa agaacgagaa agagaattag ctaagtaaaa
    10501 gtcaggagaa ccctgatttt tctttactgg aagtggcctt tagattagaa gactgaaaat
    10561 aagttaaagt cttaaactaa ttttcacagc taagaatagt agaagttaat ctgataaaaa
    10621 tcgaaaaaac cagtggaatt ctgtgtcagg gtaagttcca ctggttttca tagtctatta
    10681 aagttcgaat gaaacctatt tatagtagat tgaaactaga atagtacacc tctaattcta
    10741 aaacattgtt agaaatcgat ttgactgtcc tgatctattc gtcctattct tatttcattt
    10801 tactatattt tggtgcaata agtgaaaagt agaccgaata atataaggat tgattttata
    10861 gtttttaaac tcaaatgaat tgaaataaag agagtacgaa aattctcatc tgaaagtatt
    10921 ttagaataat tctcttcgtg aatttcttca aaacagatag cttcatctta ggtatgtgat
    10981 ttctttttgc atttttgagt tagataaggt ataatggttt tattgtcttt tggggtcgtt
    11041 acggattcga caggcattat gaggcatatt ttgcgactcg tgtggcgacg taaacgctca
    11101 gttaaatata actgcaaaaa ataacacttc ttacgctcta gctgcctaaa aaccagcagg
    11161 cgtgacccga tttggattgc tcgtgttcaa tgacaggtct tattattagc gagatacgat
    11221 taagccttgt ctagcggttt gataagagat tgatagactc gcagtttcta gacttgagtt
    11281 atgtgtcgag gggctgttaa aataatacat aacctatggt tgtagacaaa tatgttggca
    11341 ggtgtttgga cgtgggttcg actcccaccg gctccattat tcctttgcat tccttggtaa
    11401 aacgttgtta aatcaacgtt ttttattttt atctttggta ttcctttgca ttcttttgct
    11461 aaaaagggag tcacaaacag accctatttt aaaaaaagga tagaaaaaag gatacaacat
    11521 ttgtcgcatc ctaaaaataa tcttttttcg acggaagaca tgggattcga acccacgcac
    11581 gctattacac gcctaccgcg tttccaacac ggcctcttaa gcctcttgag taatcttcca
    11641 atacttactc aaatagtcta ccataaaggc tcttatcttg caataaaaat tctagaaata
    11701 agaaaaaatg atagattttg aaagaaaatg ataaaaaatg cttgacttcg aaagaaagta
    11761 tgatagaatg aatagtgtaa acgataacag gaggtgattc agtgttaaaa acagaacgta
    11821 aacaactaat tttagaggag ttaaatcagc atcatgtagt ttctctagaa aaattagtta
    11881 gtttgctaga aacgtcagaa tcaacggttc gaagagactt ggatgagttg gaagcggaaa
    11941 acaagcttcg tcgtgtgcat ggtggagcag aactccccca ctccttacag gaagaagaaa
    12001 ccattcaaga aaaatctgtc aaaaaccttc aagaaaagaa gttgctggct cagaaagcag
    12061 cctctctcat taaagaaaaa gatgtcatct ttatcgatgc tggaacaaca actgcttttt
    12121 tgattcatga attggtcaat aagaatgtta cagttgtgac caactccatt caccatgccg
    12181 ctcagttggt tgaaaagcag attccaactg tcatggttgg aggaaacgtc aagacggcga
    12241 cagatgctag tatcgggggc gttgctctta accagattaa ccaattgcac tttgaccgtg
    12301 cctttatcgg aatgaatggt gttgacgatg gctattatac gactcctgat atggaggagg
    12361 gagctgtgaa aagagctatt ttggagaatg ccaagcagac ctacgtcttg gtggattcgt
    12421 caaaaattgg acaaacttgc tttgccaagg tagcaccact caaacgcgct atcgttatca
    12481 ctagtcaagg gcatgagctc ttgcaggtta ttaaggagaa aacggaggta atagaagtat
    12541 gatttataca gtcacactca atccatccat tgactatatc gttcgtttgg accaagtcaa
    12601 agttggtagt gtcaatcgta tggacagtga tgataagttt gctggtggga aaggaatcaa
    12661 tgtcagccgt gtcttgaaac gtttgaatat accaaataca gcgacgggat ttatcggtgg
    12721 ctttactggt aaatttatca cagatactct agcagaggaa gaaatcgaga cacgttttgt
    12781 ccaagtggca gaagatactc gtatcaatgt taaaatcaaa gcagaccaag aaacagaaat
    12841 caacggaacg ggtccaactg ttgaaccggt tcagctagaa gaattgaaag ctattttatc
    12901 tagtctgaca gtagaagata cagttgtctt tgcaggttca agtgctaaaa atctaggcaa
    12961 tgttatctat aaggatttga tttccttgac gcgccagact ggtgcgcaag tggtctgtga
    13021 ctttgaagga cagaccttaa ttgatagttt ggactaccag cctcttcttg taaaaccaaa
    13081 caatcatgaa cttggagcga tttttggggt taaactcgaa agtttagatg aaattgagaa
    13141 atacgctcgt gagttactgg ctaagggtgc tcaaaatgtt attatctcta tggctggtga
    13201 tggcgccctt cttgtcacat ctgagggagc ttacttcgct aaaccaatca aaggaacagt
    13261 caaaaattca gttggagctg gtgattctat ggttgctgga ttcacaggtg aatttgtcaa
    13321 atcaaaagac gcagtagaag ccttcaaatg gggagtggct tgcggaacgg caactacctt
    13381 ctcagatgac ttggcaacgg cggaatttat taaagaaaca tatggaaaag ttgaggtaga
    13441 aaaaagatga aaattcaaga cctattgaga aaagatgtca tgttgctaga tttgcaggca
    13501 actgaaaaaa cagctgtcat cgacgagatg attaaaaatt tgacagagca cggttatgta
    13561 acagattttg aaacatttaa agaaggaatt ttggcgcgtg aagctttgac ttctactggt
    13621 ttgggtgatg gaatcgcaat gcctcacagc aaaaacgctg ctgtcaaaga agcgacagtt
    13681 ctatttgcta agtcaaacaa gggtgttgac tacgagagct tggatggaca agcaactgac
    13741 ctcttcttca tgattgcagc tccagaaggt gccaatgata ctcacttggc agccttggca
    13801 gaattgtctc aatacttgat gaaagacggt tttgcagaca aacttcgtca agcaacatct
    13861 gcaggccaag ttatcgaact ttttgaccaa gcttcagaaa aaactgagga acttgttcaa
    13921 gcacctgcta atgactctgg tgactttatc gtagctgtta cagcttgtac aacaggtatt
    13981 gcccacactt acatggccca agaagccctt caaaaagtag ctgctgaaat gggggttggt
    14041 atcaaggtcg aaaccaacgg tgctagcggt gttggaaatc aactaactgc agaagatatc
    14101 cgtaaggcta aagctattat cattgcagca gacaaggccg ttgaaatgga tcgatttgat
    14161 ggaaaaccat tgatcaatcg tccagttgct gacggtatcc gtaagacaga agagctaatt
    14221 aacttggctc tttcaggaga tactgaagtc taccgtgccg ctaatggtgc caaagctgca
    14281 acagcctcta acgaaaaaca aagccttggt ggtgccttgt acaaacactt gatgagtggt
    14341 gtatctcaaa tgttaccatt cgttatcggt ggtggtatca tgattgccct tgccttcttg
    14401 attgacggtg ctttgggtgt tccaaatgaa aaccttggca atcttggttc ttaccatgag
    14461 ttagcttcta tgtttatgaa aattggtgga gctgcctttg gtttgatgct tccagtcttt
    14521 gcgggttatg ttgcctactc tattgctgaa aaaccgggtt tggtagcagg tttcgtggct
    14581 ggtgctattg ccaaagaagg ttttgccttt ggtaaaattc cttatgccgc aggtggtgaa
    14641 gcaacttcaa ctcttgcagg tgtctcatct ggtttcctag gtgcccttgt tggtggattt
    14701 atcgcaggtg ccttggttct tgccatcaag aaatacgtta aagttcctcg ttcactcgaa
    14761 ggtgctaaat caatccttct attgccactt cttggaacaa tcttgacagg atttgttatg
    14821 ctagctgtga atatcccaat ggctgcaatc aacactgcta tgaatgactt cctaggcggt
    14881 cttggaggag gttcagctgt ccttcttggt atcgtccttg gtggaatgat ggctgttgac
    14941 atgggtggac cagttaataa agcagcttat gtctttggta caggtacgct tgcagcaact
    15001 gtttcttcag gtggttctgt agccatggca gcagttatgg ctggaggaat ggtgccacca
    15061 cttgcaatct ttgtcgcaac tcttcttttc aaagataaat ttactaagga agaacgtaac
    15121 tctggtttga caaacatcat catgggcttg tcatttatca ctgagggagc gattccattt
    15181 ggtgccgctg acccagctcg tgcgattcca agcttcatcc ttggttcagc agtagcaggt
    15241 ggactcgttg gtcttactgg tatcaaactc atggcgccac acggaggaat cttcgttatc
    15301 gcccttactt caaatgctct cctttacctc gtttctgtct tggtaggagc aatcgtaagt
    15361 ggtgtggttt atggttacct acgcaaacca caagcataaa aaatagaaaa atgaaaagat
    15421 tggaccgttt ggtgcagtct ttttctcttc ccgaaatgcc tgtgaaatat ggtataatag
    15481 aagaatggca aacaagaata caagtacaac aagacggaga ccgtctaaag cagaactgga
    15541 aagaaaagaa gcgattcaac gaatgttgat ttcgttagga attgcgattt tattgatttt
    15601 cgcagccttc aaattagggg ctgcaggtat aaccctttat aatttaattc gcttgctagt
    15661 gggtagccta gcttatctgg cgatattcgg cctattaatc tatctcttct ttttcaagtg
    15721 gatacgaaaa caggaaggac tcttatctgg ctttttcacc atatttgctg gcttactctt
    15781 gatttttgag gcctacttgg tttggaaata tggtttggac aagtccgttc taaaagggac
    15841 catggctcag gttgtgacag atctgactgg ttttcgaacg actagctttg ctggaggggg
    15901 cttgatcggg gtcgctcttt atattccaac agcctttctc ttttcaaata tcggaactta
    15961 ctttattggt tctatcttga ttttagtggg ttctctccta gtcagccctt ggtctgttta
    16021 cgatattgct gaatttttca gtagaggctt tgccaaatgg tgggaagggc acgagcgtcg
    16081 aaaagaggaa cgctttgtca aacaagaaga aaaagctcgc caaaaggctg agaaagaggc
    16141 tagattagaa caagaagaga ctgaaaaaac cttactcgat ttgcctcctg ttgatatgga
    16201 aacgggtgaa attctgacag aggaagctgt tcaaaatctt ccacctattc cagaagaaaa
    16261 gtgggtggaa ccagaaatca tcctgcctca agctgaactt aaattccctg aacaggaaga
    16321 tgactcagat gacgaagatg ttcaggtcga tttttcagcc aaagaagccc ttgaatacaa
    16381 acttccaagc ttacaactct ttgcaccaga taaaccaaaa gatcaatcta aagagaagaa
    16441 aattgtcaga gaaaatatca aaatcttaga agcaaccttt gctagctttg gtattaaggt
    16501 aacagttgaa cgggccgaaa ttgggccatc agtgaccaag tatgaagtca agccggctgt
    16561 tggtgtaagg gtcaaccgca tttccaatct atcagatgac ctcgctctag ccttggctgc
    16621 caaagatgtc cggattgaag caccaatccc tgggaaatcc ctaatcggaa ttgaagtgcc
    16681 caactccgat attgccactg tatctttccg agaactatgg gaacaatcgc aaacgaaagc
    16741 agaaaatttc ttggaaattc ctttagggaa ggctgttaat ggaaccgcaa gagcttttga
    16801 cctttctaaa atgccccact tgctagttgc aggttcaacg ggttcaggga agtcagtagc
    16861 agttaacggc attattgcta gcattctcat gaaggcgaga ccagatcaag ttaaatttat
    16921 gatggtcgat cccaagatgg ttgagttatc tgtttacaat gatattcccc acctcttgat
    16981 tccagtcgtg accaatccac gtaaagccag caaggctctg caaaaggttg tggatgaaat
    17041 ggaaaaccgt tatgaactct ttgccaaggt gggagttcgg aatattgcag gttttaatgc
    17101 caaggtagaa gagttcaatt cccagtctga gtacaagcaa attccgctac cattcattgt
    17161 cgtgattgtg gatgagttgg ctgacctcat gatggtggcc agcaaggaag tggaagatgc
    17221 tatcatccgt cttgggcaga aggcgcgtgc tgcaggtatc cacatgattc ttgcaactca
    17281 gcgtccatct gttgatgtca tctctggttt gattaaggcc aatgttccat ctcgtgtagc
    17341 atttgcggtt tcatcaggaa cagactcccg tacgattttg gatgaaaatg gagcagaaaa
    17401 acttcttggt cgaggagaca tgctctttaa accgattgat gaaaatcatc cagttcgtct
    17461 ccaaggctcc tttatctcgg atgacgatgt tgagcgcatt gtgaacttca tcaaggctca
    17521 ggcagatgca gactacgatg agagttttga tccaggtgag gtttctgaaa atgaaggaga
    17581 attttcggat ggagatgctg gtggtgatcc gctttttgaa gaagctaagt ctttggttat
    17641 cgaaacacag aaagccagtg cgtctatgat tcagcgtcgt ttatcagttg gatttaaccg
    17701 tgcgacccgt ctcatggaag aactggagat agcaggtgtc atcggtccag ctgaaggtac
    17761 caaacctcga aaagtgttac aacaataaaa aaatagcttc tttccgagtt tggagggaag
    17821 ctattttagt ggctattgat tgcttttatt ttctgaagtt ggcgcattgg actgtttttc
    17881 gttttcagta gcaggtttac ttgaagcagg agtagaagag tcctgagttg ctgttttctg
    17941 atcttctttt ttctcttcct tgacgctaga ttttggtgtt tcctcttgct gtgttttttc
    18001 ttgactagtg ttagtctctt tagttggact ggtgttttcc ttaggggatt ccttttggat
    18061 ttctttgaca atggttgtcg tctggcttgt cgtaggttct tttttaatat ttttgttatt
    18121 atccaaggcg ttcatgatcg tgatacccgc ggtaatcaag ccaaggatac tagcgattgt
    18181 agcaacggtt ttttgaaaga ctgtaaagcc ttttttgatg tgttctgttt ttggttttga
    18241 agttctacga tagttagaca tacattctct cctttgatta tgatttatta tactctgttt
    18301 ctttaaaaaa atcttaaaaa aagagaaatt gccctttctt gtcgcaggct ccgtttcatg
    18361 atacaataga aggagtgatt ttagaaagcg tgagaaacat gatttacttt gataattcgg
    18421 cgacgaccag gccctatcca gaagcccttg aaacctatat gcaggtggct tcaaaaattt
    18481 taggaaatcc atctagtctc catcgtttgg gagaccaggc aacacgaatt ttagatgctt
    18541 cccgtcaaca gattgcagat ttaatcggta agaaaagtga tgaaatcttc tttacatctg
    18601 gtgggacaga aggggataac tggatcatca agggagtagc atttgaaaaa gcccagtttg
    18661 gcaagcacat catcgtatca gccattgaac atccagcagt taaggaatca gccctctggt
    18721 tgaaagctca aggttttgaa gtggattttg ctccagttga taacaaagga tttgtggatg
    18781 ttgaggcgct agaagatttg ataagacctg atacgaccct cgtttccatc atggcagtta
    18841 acaatgaaat tggctctgtt cagcccattg aggctatttc aaaactattg gcagacaagc
    18901 caactatttc cttccacgtt gatgcggttc aggcgcttgc caagattccg actgaaaagt
    18961 atctgacaga acgagtggat ttcgcgactt tctctggtca caagttccac ggaatccgtg
    19021 gtgttggttt tatctatatc aagtctggca agaagattac gcctctttta acaggtggtg
    19081 gtcaggaacg tgattaccgt tcgacaactg aaaatgtggc aggaattgca gcgaccgcta
    19141 aggctctccg tttatctatg gaaaagctag atatctttag gagcaagact gggcagatga
    19201 aggcagtgat tcgtcaagca cttctggact atccggatat atttgtcttt tcagatgagg
    19261 aagacttcgc ccctcatatt ctgacttttg gaatcaaggg tgttcgtggt gaggtcattg
    19321 ttcacgcctt tgaagactat gatattttca tctcaacgac ctcggcttgt tcgtccaagg
    19381 ctgggaaacc agccggaacc ctgattgcta tgggagtgga caaggataag gctcagtcag
    19441 ctgtgcgtct tagtctagac cttgaaaatg atatgagtca ggtcgagcag ttcttgacca
    19501 agctaaaatt aatttacaat caaactagaa aagtaagata ggagcattca tgcagtattc
    19561 agaaattatg attcgctacg gtgagctgtc aaccaagggc aaaaatcgta tgcgtttcat
    19621 caataaactt cgcaataata tttcagacgt tttgtctatc tatccccaag ttaaggtaac
    19681 agcagatcgc gaccgtgccc acgcttacct caatggagca gattacacag cagtagcaga
    19741 atcgctcaaa caagtatttg gaattcaaaa cttttcccct gtttataagg ttgaaaaatc
    19801 tgtagaagtt ctgaagtctg ctgtccaaga gattatgcag gacatctaca aggaaggcat
    19861 gacctttaaa atctctagca agcgtagcga ccacaccttt gaattggaca gtcgtgaact
    19921 caaccaaacg cttggaaggg ctgtattcga agccattcca aacgtacaag ctcaaatgaa
    19981 aagtcctgac atcaatcttc aggtggagat acgtgaagaa gcagcctatc tttcttatga
    20041 aaccgttcga ggggcaggtg gattaccagt gggaacttct ggtaagggca tgctcatgtt
    20101 gtcaggggga atcgattccc ctgtagctgg ctatctagcg cttaaacgag gggtagatat
    20161 agaggcagtt cactttgcca gcccacctta cacgagtcct ggtgctctta aaaaagccca
    20221 agatttgacc cgtaaattaa ccaaatttgg gggaaatatc cagtttatcg aagttccttt
    20281 tacagagatt caagaggaaa tcaaagccaa agcgccagaa gcctacctta tgaccttgac
    20341 gcgtcgtttt atgatgcgta ttactgaccg tattcgtgag gtacgaaatg gtttagttat
    20401 catcaatggg gaaagtctag gtcaagtagc cagccaaacc cttgaaagta tgaaggctat
    20461 caatgctgtt accaacactc ccatcattcg tcctgtggtt accatggaca agttggaaat
    20521 cattgacatc gcccaggaaa tcgatacctt tgacatttca atccaaccgt ttgaagactg
    20581 ttgtaccatt tttgcaccag atcgtccaaa aacaaatcct aaaattaaga atgcggagca
    20641 gtacgaagcg cgtatggatg ttgaaggctt ggttgagcga gcagtggctg gaatcatgat
    20701 tactgaaatc acacctcaag ccgaaaaaga tgaagttgat gacttgattg acaatctgct
    20761 ctaattcaga aaatccaaaa gaatagcgaa aatcagtaaa aaaagttagt tttttctcta
    20821 aaaacaggta aaaaactaac tttttttatt tttatgatat aatgatataa aattttgaat
    20881 atagagagtt ttctggcaat gaatcaatcc tacttttatc taaaaatgaa agaacacaaa
    20941 ctcaaggttc cttatacagg taaggagcgc cgtgtacgta ttcttcttcc taaagattat
    21001 gagaaagata cagaccgttc ctatcctgtt gtatactttc atgacgggca aaatgttttt
    21061 aatagcaaag agtctttcat tggacattca tggaagatta tcccagctat caaacgaaat
    21121 ccggatatca gtcgcatgat tgtcgttgct attgacaatg atggtatggg gcggatgaat
    21181 gagtatgcgg cttggaagtt ccaagaatct cctatcccag agcagcagtt tggtggtaag
    21241 ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc cttttatcga tgagacctat
    21301 cgtacaaaag cagactgcca gcatacggct atgattggtt cctcactagg aggcaatata
    21361 cccagtttat cggtttggaa taccaagacc aaattggttg cttgggcgtt ttttcatctg
    21421 caaactggct ccaccaagaa gcctttaacc gctatatcga gtgccagaaa ctatcgcctg
    21481 accagcgcat cttcatctat gtaggaacag aagaagcaga tgatacagac aagaccttga
    21541 tggatggcaa tatcaaacaa gcctatatcg actcgtcgct ttgctattac catgatttga
    21601 tagcaggggg agtacatctg gataatcttg tgctaaaagt tcagtctggt gccatccata
    21661 gtgaaatccc ttggtcagaa aatctaccag attgtctgag attttttgca gaaaaatggt
    21721 aagttaagaa aggaaaaaac gaaatgcata ttgaacatct tagccactgg agtggtcatc
    21781 ttaaccgtga aatgtacctt aaccgttatg gacatggtgg gattccagtt gtggtctttg
    21841 cttcatcagg tggtagtcac aacgaatact atgattttgg catgattgat gcctgtgctt
    21901 cctttatcga ggaaggcctt gtccagttct ttaccctatc tagtttggat agtgagagct
    21961 ggttggttac ttggaaaaat gctcatgacc aagcggaaat gcaccgtgcc tacgaatgtt
    22021 atgtgattga ggaggccatt cttttatcaa gcacaagaca ggttggtttg atggcatgat
    22081 gacgacaggt tgctctatgg gagcctatca tgcactcaat ttcttcctcc agcatccaga
    22141 tgtctttacc aaagtgattg ctctcagtgg tgtttacgac gcacgtttct ttgtcggtga
    22201 ttactacaac gatgatgcta tttaccaaaa ctcgccagta gattatattt ggaaccaaaa
    22261 cgacggctgg tttattgacc gttaccgtca ggcagagatt gtgctgtgta cggggcttgg
    22321 agcctgggaa caagatggtt tgccatcctt ttacaagctc aaagaagcct ttgacaagaa
    22381 acaaattcca gcctggtttg ctgaatgggg acatgatgtc gcccatgact gggaatggtg
    22441 gcgtaaacaa atgccttatt tcctcggtaa tctctattta taaaaggagt tacctatgaa
    22501 ttaccttgtt atttctccct actatccaca aaactttcaa cagtttacca tcgaactagc
    22561 taataaaggc atcacagtct tgggaattgg tcaagagtct tacgagcaat tggatgagcc
    22621 cttgcgcaat agcttgaccg agtattttcg tgttgataat cttgagaaca tagatgaagt
    22681 caaacgtgca gttgcttttc tcttttataa acatggtcca attgaccgca tcgagtctca
    22741 caatgaatac tggcttgagc tagacgcaac actcagagaa caattcaatg tttttggtgc
    22801 caaaccagag gatctcaaaa agacgaaata taagtctgaa atgaagaaac ttttcaaaaa
    22861 agcaggtgtt cctgtggtac ctggagctgt tatcaagacg gaagcagatg ttgatcaagc
    22921 agtgaaagaa atcggtcttc caatgattgc caaacctgat aatggagtgg gagcagccac
    22981 aacctttaaa cttgagacag aagacgatat caatcacttc aagcaagaat gggaccattc
    23041 aaccctttat ttctttgaaa aatttgtcac ttccagcgaa atctgtacct ttgacgggct
    23101 cgtggacaag gatggaaaga ttgtcttctc aacaaccttt gactacgcct atacaccgct
    23161 tgacctcatg atttataaga tggacaattc ttattatgtg ctcaaggata tggatcctaa
    23221 actgcgcaag tatggggaag caattgtcaa agaatttggt atgaaagaac ggtttttcca
    23281 tattgagttc ttccgtgagg gggacgatta tattaccatc gagtacaata accgccctgc
    23341 aggtggtttt accattgatg tttataactt tgctcattcc ttggacctct atcgtggcta
    23401 tgcagctatt gtcgcaggag aggagttccc ggcgtcagac tttgaaactc agtattgttt
    23461 ggctacttct cgccgtgcaa atgctcacta tgtttattca gaagaggatt tgcttgccaa
    23521 atatagccag cagttcaaag ttaaaaaagt catgccagct gccttcgcgg aacttcaagg
    23581 agattacctg tatatgctga ccactccgag tcgacaagaa atggagcaga tgattgcaga
    23641 tttcggacaa cgtcaagaat aagaactatc ggattaagga aattaactcc cttaatcctt
    23701 ttgttttgtc tgataaaaaa taagagcatc ccaacaaggt agctatcata aaacttgttc
    23761 gataactatt tgaagcagga ttaggtggtc agaaattgaa ttttaatatt tcaattgagt
    23821 catagtattg tgtttgcgta tccttaaatc agctaaaagg atccatgacg acacctatac
    23881 gatatagttt tcaagatacc aaacaagtct attaatactc aatgaaaatc aaagagcaaa
    23941 ctaggaagct agccgcaggt ttctcaaaac actgttttga ggttgtggat agaactgaca
    24001 gagtcagtat catataccta cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa
    24061 gagtataaaa tattcaggtg acgcatagat atagttaatt gaagctttgt ttgaaatctg
    24121 ataaaataat gatattacta agttttaaaa actaaagaaa agggaagata tgattacagg
    24181 cgaattaaaa aataaaatcg atcagctgtg ggaaattctt tggacagaag gaaacgcaaa
    24241 tcctttaaca aatattgaac agttgactta tctcttattt atgaaagatt tggatagtgt
    24301 cgagcttgga cgtgaaagtg atgctgaatt tctagggatt ccttatgagg gagtttttcc
    24361 aaaagataaa cctgaatacc gttggtcaac ttttaaaaat ataggagatg ctcaggaagt
    24421 ttatcgttta atgactcagg agatttttcc gtttattaaa aatctcaagg gggatacaga
    24481 tgatacagcc ttttcacgat atatgcgaga agctattttt caaataaata aacctgctac
    24541 gcttcaaaag gcaatttcta tcttagatgt ttttccaact aggggattag atgtagattt
    24601 tgataatgac aaacaaagta ttactgatat cggagatatc tatgaatatc tgttatcaaa
    24661 attgtcgacc gcaggtaaaa atggacagtt ccgtacacct cgtcacatca tcgatatgat
    24721 ggttgagttg atgcaaccga ctatcaaaga tatcatctca gatcccgcta tgggttctgc
    24781 tggcttctta gtatctgcta gccgttactt aaagcgtaag aaagatgaat gggaaaccaa
    24841 tacagataat atcaatcatt ttcataatca gatgtttcat ggaaatgata cggatacgac
    24901 tatgttgaga cttggggcga tgaacatgat gctacatgga gtagaaaatc cacaaatcag
    24961 ttaccttgac tcgctgtctc aagataatga agaagccgat aaatatactt tggttttagc
    25021 aaatcctcct tttaagggct cacttgacta caattcaacc tctaatgacc ttcttgcaac
    25081 cgtaaaaacc aaaaaaacag aattactctt tctttctctt ttcttgcgaa ctttaaaacc
    25141 aggtggacga gcagcagtta tcgtacctga tggtgtcctt tttggttcgt ctaaagctca
    25201 taaaggaatt cgtcaggaaa ttgtagagaa tcataagctt gatgctgtaa tctcaatgcc
    25261 tagtggtgtg ttcaagcctt atgctggagt ttcaactgct attctcatct ttacaaaaac
    25321 tggtaatggt ggtactgaca aagtctggtt ttacgatatg aaagcggatg gtttaagttt
    25381 ggatgataag cgacaaccga ttagcgacaa tgatattcca gatattatcg aacgctttca
    25441 tcatcttgaa aaagaagcag aacgtcagag aacggatcaa tctttctttg ttccagttgc
    25501 tgagataaag gaaaatgatt atgatttgtc tatcaataaa tataaagaga ttgagtatga
    25561 aaaagttgag tatgaaccaa cagaggtcat cttaaagaaa atcaatgatt tagaaaaaga
    25621 aattcaagct ggcttggctg aattagaaaa attactcaag tagggaggtg gctgtatgaa
    25681 aaaagtgaag ttgggggaag tcttatctct aaaaaaagga aagaaagcca ctgtacttgc
    25741 tgaacaaaca actctaagcc aacgttatat tcaaatagat gatttaagaa ataataataa
    25801 tttaaaattc actgaaagtt taaatatgac tgaagcactc ccagatgata ttctaatagc
    25861 atgggatggt gctaatgcag gaacagttgg ctatgggtta tcgggagctg ttggtagtac
    25921 aattacggtc ttaaaaaaga atgagcgata caaagaaaaa attatatcag attacttggg
    25981 agtctttttg gaaagtaaat cgcagtattt acgagatcat tcaacaggtg caactattcc
    26041 tcatttaaac aagaatatat tacttgattt acaattagaa ttgctaggta tcgaagaaca
    26101 agagaacatt atctgtattc ttaatacgat taaaaggctt attactaaaa gaaaatttca
    26161 gttagatgaa ctaaacttgc tcgtcaaatc ccgatttaac gagatgtttg gggaaaataa
    26221 aatatttgaa agcattgata acttatttga tattatagat ggtgataggg gcaaaaatta
    26281 tcctaaatca gatgagttgt ttagtgagga gtactgttta tttttaaata caaagaatgt
    26341 tactaaaaac ggattttcat tcgatacaaa gcaatttatc actaaaacaa aggataaatt
    26401 acttcgaaaa ggcaaacttg agcgttatga tatagtcttg acaacaagag gtactgttgg
    26461 aaatgtagcg tactacgatg aattaataaa atataaacat ttacgtataa attcaggtat
    26521 ggtaatatta cgtcccaaga caccaaatct aaatcagaaa tttattatcc atgttttaag
    26581 gaataataat tatagtcgag tgatatcagg aagtgctcag cctcagttac caattacaaa
    26641 attaaaaaaa atacttctcc ccctcccccc actagccctc caaaatgagt tcgcagactt
    26701 tgtagtccag gtcgacaaat cacaattggc aatccaaaaa tctctggaag aacttgaaac
    26761 tttgaagaaa tctctgatgc aggagtattt tggctgatat tctgccattg taattacggt
    26821 aatgatttgt tataatactt caaaggagga aatcagatgg tagtaaaaac aagaaaacaa
    26881 ggaaattcaa tcaccattac gattccaagt gaatttaata ttccaagtgg tgttaaatac
    26941 gaagcgaaat tgttaccaag tggtgagatt atctttactc ctgaagaatt ggggcagcag
    27001 gtttcttatg tatctgatga tgcctttgac ttaaatttag ataaaatatt tgacgaatac
    27061 gacgatgttt tcaaagcttt ggtggaaaaa tgacaatcta tctgacagaa aagcaaattg
    27121 aaaaaataaa tgctttagca attcaacggt attctccaaa tgagaaaatt caaacagtta
    27181 gttcttctgc cttaaatatg attgtgaact taccagaaca atttgtcttt gggaagtctc
    27241 tttatccaac aatttttgat aaagcaacga tactatttgt ccaattgata aagaagcatg
    27301 tttttgctaa tgctaataaa agaactgctt tcttcgtttt ggtcaaattt ttacaattaa
    27361 acggctatcg tttttctgta acggtagaag aagcagtaaa aatgtgtgta accatcgcag
    27421 tagaagcttt aactgatgaa aaaatgacaa gctactccaa atgggtttct gaacattctg
    27481 ttagagaaaa ggtcaaaaag taacctagta tgctggattt gaatgagcac aagaaaataa
    27541 atgaacagac aatattagaa ttctgtaatg cagaaactga tattgtctct ttttattgat
    27601 gaataagaaa gtgagaaatt atggaatcaa aagttacaat tatcatgcaa gaaatgttac
    27661 ctcttttaaa taatgaacaa ttactagcgt tgagagagag tttagaacat catctagtag
    27721 acggaaaaaa gcagcagaag tattcgaata ataacctgtt gcaactattt attaccgcca
    27781 agcaggtaga gggctgtagc tcaaaaacaa ttcgttatta ccagaggacg attgaaaact
    27841 tgtttaatgc tattaaagag tctgtgacac aactcacaac agatgattta aggagttatt
    27901 tagcaaatta ccagtctgaa aaggattgta gtaaggcaaa tttagacaat attaggcgta
    27961 tattgtcttc tttttttgct tggcttgagc aagaggaata tatcattaaa aatcccattc
    28021 gacggataaa gaaaattaag actgagcaaa atgtgaagga aacttatact gatgaacatt
    28081 tggaaattat gcgtgataac tgtgaaaatt tgagagattt ggcaataata gacctactag
    28141 catcgacagg tatgcgtgta ggggagcttg tacagttgaa tcgttcagat attgattttg
    28201 aaaacagaga gtgtgttgtc tttggtaaag gaaagaagga gagaccagta tattttgacg
    28261 ctcggacgaa aattcattta agaaattatc ttaacgacag aaaagatagt caccctgctc
    28321 tttttgtaac gctagttgga aaagcccaga gacttggaat tgctggtgta gagattcgct
    28381 taagaaagtt aggagacaaa ctcggcatac aaaaggttca cccacataag ttcagaagaa
    28441 ctttagcgac taaggcaatt gataaaggta tgcctatcga acaagtccaa aaactgctag
    28501 gtcatagcaa gattgacaca accttggcct atgccatggt caatcaaaat aatgtcaagc
    28561 attcacacca aaaattcatc tcttaaaagc aaattcccga tttaacgaga tgtttgggga
    28621 tcctttaaat aataacaaga aatttgcagt aaaaacggga caacagtgtt ttaaattttc
    28681 aagtggaaaa tttcttgata aacatgatag agtttttgaa ggttatcctg cctatggtgg
    28741 aaatggcatt gcttggaaaa gtcgaaaata tttaattgat aatcctacta tcatcattgg
    28801 tcgtgtaggt gcatattgtg gtaatgtaag aactacccac ggtaaggtat ggataagtga
    28861 caatgctata tatataaaag aatttaagaa ttccgatttc aatcttgtat ttttattaga
    28921 attaatgaaa gtaattgatt ttagtaaatt tgctgatttc tcaggtcaac caaagataac
    28981 tcaaaaacca ttagaaaatc agaaatatat cctcccccct ctagccctcc aaaatgagtt
    29041 cgcagacttt gtagccctgg tcgacaaatc acaatttgct tgtgagatag ctatataaaa
    29101 gtgtggagaa atagcttgaa atttagtata atatagctaa actatttgtt taaagtgaga
    29161 aaaaaatggg aaattttagc tttcttttaa aaaatgacga atatgaatct ttttcaaaac
    29221 cttgcattga agctgagaat atgattgcta catcaactgt ggctactgcc tttatggcgc
    29281 gtcgtgcttt agagcaggct gtccattgga tatatagtca cgattcatat ttagaagctc
    29341 cctatcgtgc tactctatct tctttagtat gggatgatga ttttagggat atcgtagatt
    29401 ctgaactcca caagcagata gttctgttga ttcggtgggg aaaccatgct gctcatggtg
    29461 gtgaaattaa ggaacgagaa gcgattttag ctttgcatca tttgtatcag tttgttaatt
    29521 ttatcgatta ttgttacagc aatgagtttg tggagcgtta ttttgatgag aagtgcttac
    29581 cactttcagc aaacatcaaa taccgagaaa ctccacaatc tatgataaag ttacaagaca
    29641 gtttaccaga actgcctgat tttcatgaac agatggctgc tcagtccgta gaagttcaag
    29701 agacttatac tgaaaaacgt gagactgcag cgcaacggca agatgtgcct ttccatattg
    29761 atcaattatc tgaggcagag acaagaaagc tctttattga tatcgatctc cgtttagcag
    29821 gatggatatt tggagaaaac tgttgtgttg agatagccgt tgatggtctc aagcacggtt
    29881 caggaattgg ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt ttagcgattg
    29941 tggaggctaa aaaagcctct gtcaatccag aagtagggga agtacaggtc aaagaatatg
    30001 ctgaagcttt ggagaaacat atcggctatc agccaatttg ctttattaca aatgggttga
    30061 agcactatat acttgatggt ccgaaccgac gccagattgc aggcttttac tctcaagaag
    30121 aattgcaatt agtgatggat agacgtcatc ttcaaaaacc acttgaggat atttctagta
    30181 aaattaggga cgatatttcc gggcgtcact accaaaaaca tgccattgca agcgtttgtg
    30241 aagctttctc taatcatcgt agacaggcac ttttggttat ggcaactggg gcggggaaaa
    30301 ctcgtacagc agtttctcta gttgatatct tatcacgtca taactgggta aaaaacgttc
    30361 tcttcttagc cgatagaact tccttggtta agcaagccta tgattcgttt agaaaattac
    30421 tcccagatct ttccgtttgt aacttcttag aagataaaga aggagctcaa tcaagtcgta
    30481 tggtcttttc aacttatccg accatgattg gagcgattag tggtcaagaa gaagtaaatc
    30541 aacgcccttt tactgttggg cattttgacc ttatcataat tgacgaatct caccgttcta
    30601 tttatcagaa atacaagtcc atttttgatt attttgatgc aagaattgta ggcttaacag
    30661 ctactccgcg tcaagattta gataaaaaca cctatggatt ctttaatttg gagaatgggg
    30721 ttccaacata tgcatatgat ttggaagagg ctgttaaaga cggatattta gtagcctatc
    30781 attctatcga aaccaaactg aaactaccta cggatggtct acattatgat gatttgtccg
    30841 aagaagaaaa ggaacatttt gatagcaaat ttgaagacga tagctgtgaa aaagatattg
    30901 atgggagtgt atttaattcc tttgttttca ataaaagtac agtagaaatt gttttaaatg
    30961 aactcatgac aagaggaatt cagacagcct cgggtgatga aattggtaaa actattattt
    31021 ttgctaaaaa tcatgatcat gcagaatata tcagaggtat ttttaacaac cgctatcctg
    31081 aaaaagggag cgactatgct caggtgattg attatagtat taagcattat cagaccttga
    31141 ttgatgattt taaaattgag gagaagtatc ctcaaattgc gatttctgtc gatatgttag
    31201 atacaggtat tgatgtacca gaggttgtta atttagtctt cttcaagaaa gtacgctcta
    31261 aaactaagtt ttggcagatg attggtcgag gaacccgtct atgtaaagat ttatttggac
    31321 ctgagcagga taaggaaaac ttcttggtat ttgattatgg ggataatttt gattattttc
    31381 gtgcagatcc aagagatgga gagggtcgtc acattgtttc gttgactcag cgtttattta
    31441 atatcaaagt ggacttgatt cgagaacttc agggactcca ataccaagaa gatcagtttg
    31501 cgagagcata ccgtcagcag cttgtctcgg aacttcaagg tcgtatagag agcttaaatg
    31561 agttggactt cagggttcgt atggttttag atacagttta tagctatagg aaattggaaa
    31621 gttggcagaa tctaactgct gttacaagtg aaaccattca aaaaaatctc tctccgcttt
    31681 tatttgatga agataaagaa gatgagatgg ccaggagatt tgatttgtgg ttgcttcata
    31741 ttcagttggg gcaactgaca gctaaatctt ccactgttca tatttcccaa gtgatgaaga
    31801 cggctagagc tctttctgct attggcaata tcccgcaggt ttttgagcag gctgaaatta
    31861 tcaggaaagt acaggagcct gaattttgga aagaagttaa cttgtctgat ttggaaaaaa
    31921 ttcgtcttgc tattcgagat ttattacagt ttttggataa aacagaccgt aaaccctact
    31981 atgttaactt tgaagatcgt atactctcca ctgttcacga gaccacagca tttttgcagg
    32041 tcaacgatct tcggtcttac aatgaaaaag ttgagcatta tttgaaaact catctggatg
    32101 aggagtccat ttctaagcta taccataata aaaagttgac atctgatgat atgcttgcac
    32161 ttgaaaaatt gctttgggaa aaattaggta gtaaagcaga ctaccaaagt cattatgaaa
    32221 ataaggcaat tccgagattg gttcgtgaga ttattggctt agatagagag tctgccaatc
    32281 gtattttttc taaatttttg tcggatgaga atcttaatgc caggcagatt tcatttgtaa
    32341 aattgattgt agactacatt gtagaaaatg gttttttaga gacgaaagtg ttaacgcaag
    32401 agccgtttaa atcttatggt tctgttcaac tactcttcca acaccaacta ccagtacttc
    32461 gtaatattgt tcaaatcatt gaacttatca ataatcgagc tggagaagcg gcttaaattc
    32521 taaagtgatt gccatgctga gactcattta aaattaaaaa gagtagaaat ttatgctata
    32581 tatgagaagt tttattagga agaatgtcat cgttttccta gaatacagta tcagttgtta
    32641 agtggttgat aaatttcaaa gtagatactt gtaccacgat gtttgttgat cgagttatta
    32701 acaaaagagc tactttgatt ttaaagaaat agaaaacaaa aagccgagca agaattcaat
    32761 tgcaggagaa aatgaaataa tactcaatga aaatcaaaga gcaaactagg aaactagctg
    32821 caggctgctc aaaacactgt tttgaggttg cagataagac tgacgaagtc agctcaaaac
    32881 atggttttga ggttgtagat gaaactgacg aagtcagtaa ccatacctac ggcaaggcga
    32941 cgttgacgcg gattgaagag attttcgaag agtataaatc ttcctaggat aaagcaaaac
    33001 gcatagtatc aagggttttc aacacttgat actatgcgtt ttctgatgtt aaagactttc
    33061 taccagtttt tttaagcata attgttagtt gtagtcattt attattcttc aaagaaaaat
    33121 ggtggggcga attttttcag ttcttcaaag cacttttgag cagtatctgc atcttcacag
    33181 atgataagac agacatcatt accacaaagg gtagcgatag cgtcagggaa gctcaaagta
    33241 tcaatgatag aaccaaagga ttgagccagt ccaggaaggg tttttagtag gacttggtgt
    33301 tgaactgggc gcatccagac aagggcgtct tccatgtaga gttcgagacg tttttcccat
    33361 tttgagatgg aaccattgtt aagaacataa taagcgctat cttcttcgcg gacttttgat
    33421 aggttcatat ttttgatgtc gcgtgagagg gttgcctggg ttacttgaat gtcgttctta
    33481 gcaagaaggg cttgcaactc agcctgtgta tgaatcttgt tttttgtgat aagagcgcgt
    33541 ataagttggt ggcggtgttc tgatttattc ataataatgt aactcctttt agcaaggtaa
    33601 ggtaagcatg gactgagcga ggtcgacagt caagtggtag tctgtattgt cacggatggt
    33661 gatttcaaag tcagtagtat agaggactaa acggagagtg tctccttctt ttagcttgta
    33721 aatagttggc tgcagttcaa attgaacatc catccattca tctgcagtaa tatcctctac
    33781 taacagtaaa tcatttctat tttgtaaatt aaggtaacct tttgtcacga ctcgttgtgc
    33841 ctctggtcta aatggcaatt cacagagatt ttccaacatg tgatagcgac cgttgtcaat
    33901 ggttctagca cttaaaatag ctggataagg ttgtaggtat ttcttttgcc caaattctag
    33961 cagttgggca gataagagcc ccttgtttgt actggatttg atacgaagat tgagctgagc
    34021 gcgaccgttt aggtggagat ctttagtcac aggaaggtta atagtaatct gattggcttt
    34081 cccttgatag agctctgtat tgaaggtttg gtatgtctta ccatagcgct caaaatcctt
    34141 atctgggtac tggttttgaa tagcttgctc ttcttgacca agtgagaagg tttcacagtt
    34201 ttcttgccca ccgaagttat caagtgataa ccaagtctgt ggagctgtat tgtcctgcca
    34261 gataacagta ggaagttgaa agtctgtttc ctgtcctagt aatttcttgg tcaataaggc
    34321 atttatggac tcacggaagt caattgattg ccaattgttc atgtaaacat gggcaccatt
    34381 atggaaaaag agatgcttgt ttatatgagt aggaagagca tggaacatct ggtaaacatg
    34441 aagtggtttg acattccaat cctgagaacc atgagtaaag acaacctctg cctttacttt
    34501 atgggcattg agcagataat tgcggtcatg ccaaaactga ttgtagtccc cagtttttcg
    34561 gtctagctga gctttcactt tttctaagtc agcttggtga gcttcattgc cacggatata
    34621 gtcgccagct aagagattac gagaataggt taactcagca agggagtcaa agtcctcacc
    34681 tggataacca cctgggctag tcaccagacc gttttcacgg tagtagttgt accatgatga
    34741 aattcctgcc tcggcaatga taacttctaa accatcgact cctgtagtcg caagaccatt
    34801 ggacatggta cctagatagg aaagtcctgt tgtagcaact tttccgtttg accaatcagc
    34861 cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg caacggccgt taagccaatc
    34921 gatgacattt ttataagcct cgatttgctg gtagtctcca ttagtcatga aacctgtcga
    34981 gtctttggta ccaacacctg agacatagag attggcaaag cctctcggaa ggaagtagtc
    35041 gtttagtgta tagctagagt tgatgtgagt tagcttttcc tcagcctctg ctataagctc
    35101 agctttacct tggggttgga cgagatttag ttgaggtttc tctagctcaa tcttgtgagg
    35161 aagcttaacc tcaagctcgc cctccatctt gtagagagcc ttgtcactag ccttgtcatt
    35221 ggttccctga tgataagggc tggctgtcat gatggcaggg atttttccat caaaacgagg
    35281 gcgaataatg ctaaccttta ctaggtctga tagccctttt tggtcagtat cgacacgaga
    35341 ctcaacgtaa acgacttcac gaatgacatc ctggttagaa aaagtagcca aactcttgcc
    35401 gttaaagtag tggtagtcat tatcctccgg aataagacca tcactaacaa gttggtcgat
    35461 aagagtattt ccttttttgg tgcgagtatt gagtaactga tagagatttt caatcaagtc
    35521 accatatata atgggaaatc cagtttcttt acgaaaaacg tcactatctt cgaagtcaac
    35581 caaataagaa aagcctaaaa gttgaaaagc aacagtataa aaaatatctg ctgtcagttc
    35641 atcttctgat tgaaaaaatg tcagcaggtc tgttttttta tcagctgcta ggatagaaag
    35701 tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt aaaaaggttt caagtgagtc
    35761 tttgtgattg gctgtatttt gtaaatcaaa gccacatttt tttagttcag ataagacatt
    35821 ttcttttgga aaattgatat aactatattg attaaaacgc atagaacctc catatagaat
    35881 gacagttaag gttattatat caaaaaaaaa gcagaaaggg aattgttaac ttcaaaagga
    35941 aataatccaa taaa
//
LOCUS       DAVLHM010000022        35215 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLHM010000022 DAVLHM010000000
VERSION     DAVLHM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.022"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(34..684)
                     /locus_tag="VXE45_001132"
     CDS             complement(34..684)
                     /locus_tag="VXE45_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0789168.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            796..1638
                     /locus_tag="VXE45_001133"
     CDS             796..1638
                     /locus_tag="VXE45_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0789169.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            1714..2151
                     /locus_tag="VXE45_001134"
     CDS             1714..2151
                     /locus_tag="VXE45_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0789170.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            2220..2522
                     /locus_tag="VXE45_001135"
     CDS             2220..2522
                     /locus_tag="VXE45_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789171.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(2613..3686)
                     /locus_tag="VXE45_001136"
     CDS             complement(2613..3686)
                     /locus_tag="VXE45_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0789172.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            3842..4519
                     /locus_tag="VXE45_001137"
     CDS             3842..4519
                     /locus_tag="VXE45_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0789173.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            4512..5486
                     /locus_tag="VXE45_001138"
     CDS             4512..5486
                     /locus_tag="VXE45_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0789174.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VXE45_001139"
     CDS             complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VXE45_001139"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0789175.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(7536..7859)
                     /locus_tag="VXE45_001140"
     CDS             complement(7536..7859)
                     /locus_tag="VXE45_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0789176.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            8718..9347
                     /locus_tag="VXE45_001141"
     CDS             8718..9347
                     /locus_tag="VXE45_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0789177.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            9488..9757
                     /gene="rpsO"
                     /locus_tag="VXE45_001142"
     CDS             9488..9757
                     /gene="rpsO"
                     /locus_tag="VXE45_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0789178.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            10572..11186
                     /locus_tag="VXE45_001143"
     CDS             10572..11186
                     /locus_tag="VXE45_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0789179.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIQRL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(11479..12228)
                     /locus_tag="VXE45_001144"
     CDS             complement(11479..12228)
                     /locus_tag="VXE45_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0789180.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            12361..14697
                     /locus_tag="VXE45_001145"
     CDS             12361..14697
                     /locus_tag="VXE45_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0789181.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            complement(15134..18280)
                     /locus_tag="VXE45_001146"
                     /pseudo
     CDS             complement(15134..18280)
                     /locus_tag="VXE45_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621470.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
     gene            complement(18469..19707)
                     /locus_tag="VXE45_001147"
     CDS             complement(18469..19707)
                     /locus_tag="VXE45_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789182.1"
                     /translation="MHIFLKNRAFRQLTVNEWISSFGDTIFYLAFINYVSSYAFAPLA
                     IFLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVTLLLTSTDFSLF
                     SVFFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGG
                     VFLGLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKES
                     MKLLMTMEDVMVLLWILSISQAVLMMVEPVSAILLIHHPFMGLSTGQSLAILIMISLL
                     HVILGGLLSGFLSKKISIRLNIYWSLLMESLIVIDFLRGSFLLILLGSAGDAFSAGVL
                     SPRLQAMIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLEVVAFALIIL
                     LLIAAYLVHQMKNLPNQEEV"
     gene            complement(19709..21145)
                     /locus_tag="VXE45_001148"
     CDS             complement(19709..21145)
                     /locus_tag="VXE45_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0789183.1"
                     /translation="MTPIKDKVRRVKTPMMVNPDTDLTISSVQQDYFSLALIGFSLLT
                     GDFLSFSKGDQKTGLSAFIKICHLIKIARLDNKITKQQEYWLYDLLMMSQGEKIQKIK
                     QLKQVTSDILLNTPDFSSYFEKYNFKEEAENIKSYLLAKSMDKSGRLFPSNEFGEFVS
                     PVSFQHGFGGVLFFMNKYYVEEDENTVKEWLTKLENYEAANFLHGYSLLFGKAGFLFG
                     ILDRYEKTKERYLIDISKRLVDHLMRVYDNISNLDFALGKSGILLSLMKYCTIFDDKK
                     LANFIKNNINDAYSLLESEDNGDIYSNNFAHGRSGAAYVLKAYTDIFGDSRYQNHLQK
                     FSDGISELLEEKLSSFSKLDNLGLSWCDGVSGLILYLCLIDKERYSEIIYKSQLEMVQ
                     QYEAMGTSFCHGLSSLLQTTIYNKNQKVEQFIKKILLTRSYRNNDRLLQFQGEDGINS
                     YFDFGVGNLGIYWTLLGYTFPFELSKGD"
     gene            complement(21219..21749)
                     /locus_tag="VXE45_001149"
     CDS             complement(21219..21749)
                     /locus_tag="VXE45_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV0789184.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSYIHKLGI"
     gene            complement(21743..22211)
                     /locus_tag="VXE45_001150"
                     /pseudo
     CDS             complement(21743..22211)
                     /locus_tag="VXE45_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22760..23437
                     /locus_tag="VXE45_001151"
     CDS             22760..23437
                     /locus_tag="VXE45_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0789185.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLCKEVSPVFVQKWQKEAVKLEFALGQIPDKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23424..24221
                     /locus_tag="VXE45_001152"
     CDS             23424..24221
                     /locus_tag="VXE45_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0789186.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFGELAQHVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24238..25341
                     /locus_tag="VXE45_001153"
     CDS             24238..25341
                     /locus_tag="VXE45_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0789187.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25642..26661
                     /gene="galE"
                     /locus_tag="VXE45_001154"
     CDS             25642..26661
                     /gene="galE"
                     /locus_tag="VXE45_001154"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0789188.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26663..27598
                     /locus_tag="VXE45_001155"
     CDS             26663..27598
                     /locus_tag="VXE45_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0789189.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTNWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSYHRS"
     gene            27773..28417
                     /locus_tag="VXE45_001156"
     CDS             27773..28417
                     /locus_tag="VXE45_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789190.1"
                     /translation="MLSKEEYIEEIGLIEKQNYVEVELYPLVADIINPTLKNSLSKRY
                     VFGRRKSNMGQIYYGLSNFPDIVILDKNYQNKARKSIEIEEWKKLRGCVEIKSLKHDL
                     ITEEKIKSTISNSFEHITGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKEEIDNTIV
                     QVVNKRIETEEAGNSFDWWKNIKDLSFNYTDIYLSKDCIQEWDEFVKKVKEIEW"
     gene            28456..28557
                     /locus_tag="VXE45_001157"
                     /pseudo
     CDS             28456..28557
                     /locus_tag="VXE45_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(28608..28814)
                     /locus_tag="VXE45_001158"
     CDS             complement(28608..28814)
                     /locus_tag="VXE45_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0789191.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDILEAVKNCPTRALIGNQEA"
     gene            28866..29342
                     /locus_tag="VXE45_001159"
     CDS             28866..29342
                     /locus_tag="VXE45_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0789192.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKGFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMVTGSWFANPGDVIKIK"
     gene            29351..30022
                     /locus_tag="VXE45_001160"
     CDS             29351..30022
                     /locus_tag="VXE45_001160"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0789193.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            30153..30491
                     /locus_tag="VXE45_001161"
     CDS             30153..30491
                     /locus_tag="VXE45_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0789194.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            30494..31123
                     /locus_tag="VXE45_001162"
     CDS             30494..31123
                     /locus_tag="VXE45_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0789195.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            31363..32514
                     /locus_tag="VXE45_001163"
     CDS             31363..32514
                     /locus_tag="VXE45_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0789196.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32827..33576
                     /gene="truA"
                     /locus_tag="VXE45_001164"
     CDS             32827..33576
                     /gene="truA"
                     /locus_tag="VXE45_001164"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0789197.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            33566..34339
                     /locus_tag="VXE45_001165"
     CDS             33566..34339
                     /locus_tag="VXE45_001165"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0789198.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            34317..34778
                     /locus_tag="VXE45_001166"
     CDS             34317..34778
                     /locus_tag="VXE45_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0789199.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     AIIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35005..>35215
                     /locus_tag="VXE45_001167"
     CDS             35005..>35215
                     /locus_tag="VXE45_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0789200.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMINKV"
BASE COUNT        10323 a         6382 c         7610 g        10900 t
ORIGIN      
        1 aaaactttca gggttggtag gggacttgag aaattagttg attttctcga catagagttg
       61 ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag tgaaggtatt
      121 gctgaagcca tcaaactgct taacttggag ctggtcaccg atgtgaagtg agtgcttgtc
      181 cagataatgg agaatgtcaa aactatcgtg catccgagtc aggcggtagg cgccagcttc
      241 cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct tggcaggaat
      301 agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc tttccacgaa
      361 caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt cacttgtata
      421 gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga gctcagagac
      481 cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta ggatgagatt
      541 ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt gcatgcgagc
      601 cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa tacattttag
      661 atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta tctagtatat
      721 caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg caagagaaaa
      781 aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg aaataccacc
      841 gccttggagg ctgttttggc agatgctcgg cagctaggag tggatgaata ctggcttttg
      901 ggagatattc tcatgccagg gacagggcgt agaaggattt tggacttgtt ggatcaacta
      961 ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg tgtccgtaag
     1021 gaattggata gtactcgccc tagtcaacgc tatctcttgc gccagtgcca gtatgtttta
     1081 gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca aattcatcgt
     1141 cagtttgggg atttgacagt gggaattagc catcatctgc ctgataagaa ctgggggcga
     1201 gagttgattc atactggcaa acaagaggag tttgaccgct tggtgactca tcctccctgt
     1261 gatattgctg tttatggaca cattcaccag cagttgcttc gttacgggac tggtgggcaa
     1321 ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca gctacggaag
     1381 gacttgcggg cccagtatat gattttggag tttgatgaca agggcctggt agatatggac
     1441 ttccgacggg tagattacga tgtggcagct gaattgcagc tggctaaaga cctgagactt
     1501 ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac tcatcatcag
     1561 gaatttttga gagaattggc tcagaaagag ggttgcgatc gggagttaga cgactggttg
     1621 aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa aagaagagta
     1681 gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag atttaccatt
     1741 gcaactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt gaccagtgat
     1801 tttctggctg ctagtgttgg ggtcaatcct gtcattatca gaaagatctt gtcccagttg
     1861 aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat tgtcaaggac
     1921 cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg taagacaggt
     1981 caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc tcatattcat
     2041 gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga acttggtcag
     2101 accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta agagggataa
     2161 atgccctctt tttttctttg gataattatg ataaaatgta gctattaaag gagtaagaaa
     2221 tgtatctcgt tatagaaatt gtattagcct ttatagtgtc attttggaag gataatagaa
     2281 gtttgtggaa tccagtatta tttttattat ccctcatttc aagttatttt tatctatcct
     2341 acctttttta taaaaatgga tacgagaatg ttcagttagc tttttatgta tttgcctttg
     2401 tcttacttcc ttttttgctt tttctaagtg gcatcttttt aatctataat ggggtcattt
     2461 tgttgaaacg agagggacgt tccaagcccc attatctctc aatgctcttt gatttttatt
     2521 gactattaga ttctatttaa aaagacttag aatgaacatg aaagtatgta ttctaggtct
     2581 tttgttttgt atacatttaa ttttcaagag tattatctat ttttccatgc atggtaacga
     2641 gtatcaatca ataactgggt aaggcgaccc aaggtttctc tttcttctgg agtgagggat
     2701 tgagcttgga caaagagatg atgaatgtat tcaagcgcct ttaaggaagc caagtcattg
     2761 atagagctaa taccagcatc aagaatagtg ccaaagaaga ggtcgaagta gagctgaagt
     2821 tcttcgtcag ggactgtggc cacccattct ttaaaggttg tgtctacttg ccggctatca
     2881 ctgttggtct tatccagttg aacgaagtgc ttgtcctcaa tctgccaact aaaggtatcg
     2941 tgctgggcga tgccacccag ggcagtactc tgaacgatga tttggtgagc aggaatttcc
     3001 agcatcatac cgataatgga accttgtgga atgaatatct tgcttctatc cattatcctt
     3061 tgataacccg cagtctgtgt caattcttga tggagaccag gtgcatcaaa tgtataaact
     3121 gctgtgatct gattttgcaa actttgctca atttggctag cagcatagat agcgagattt
     3181 cctcccttgg aatgcccagc cagaataacc ttttgcttag gatgatgggc aaaaaagttc
     3241 tttaaatagc gaagggcgtg cttttgagca ggaatttcct tcatataggt caggtggaaa
     3301 tcttccttcc agccaatgat actgtcatct gtcccacgaa agacaatcag ataggtatcg
     3361 aggctgacac gataagtcat agccgcaaat tgcttttgca gttcagggtc gatgtcgttg
     3421 ataaaatggg agagtttgca atttttgaag cgcttgtgtt gagccaattc atctaataat
     3481 tgaaggcgat ttttgctagt aagcatggtg ggctctcttg gaacctgagg tgctagatct
     3541 aaaagacgtt gaggaagtgt ggagaccaga ttatcaaagg agaggtaggt gatttctatt
     3601 aaggttagaa tgtctaactc attcaaggga aggtcgtaat aagaatcata tgcgacatct
     3661 ttcagatagt caaaaatatt ggccataaga gctcctttct ttttatttat cttagcaaat
     3721 ttccctcaaa ttagctagta gcatagcctg tttgtactgg ctaaaaacag gctatttcaa
     3781 attcagtttc agaccatcta gcatggaaaa atctgttata ataatggaaa aggagaagcg
     3841 catgcacaag attttattaa tagaagatga tcaggtcatt cgtcaacaga ttgggaaaat
     3901 gctctctgaa tggggatttg aagtggtcct ggtagaagac tttatggaag ttttgagtct
     3961 atttgttcag tcggaacctc atctggtcct catggatatt ggtttgccct tgtttaatgg
     4021 ttatcactgg tgtcaggaaa tccgcaagat ttccaaggta cctatcatgt ttctttcttc
     4081 gagagaccag gctatggata ttgtcatggc aatcaatatg ggggcggatg actttgtgac
     4141 caagcctttt gaccagcagg ttcttttagc taaggttcag ggcttgttgc gtcgttccta
     4201 tgagtttggg cgtgatgaga gtttgctgga atatgctggt gttatcctca ataccaaatc
     4261 catggattta cattatcaag ggcaagtctt gaatttgacc aagaatgaat tccagatttt
     4321 acgcgtgtta tttgagcatg caggcaacat cgtagcacgt gacgacctga tgcgggaact
     4381 ttggaacagt gactttttca ttgatgataa taccctctct gtcaatgtgg ctcgtttgcg
     4441 taaaaagttg gaggagcagg gattggtagg atttatcgag accaagaaag gaatagggta
     4501 cggattgaag catgcttgat tggaaacaat tttttctagc ctatctgcgc tcccgtagtc
     4561 gtctttttat ctatctgctt tctttggcat ttcttgtctt actctttcag tttttatttg
     4621 ccagtctagg aatttacttc ctctactttt tcttcttgtg ttgctttgta accatattat
     4681 ttttcacttg ggacatattg gtggaaacgc aggtctatcg ccaggaactt ctctatggag
     4741 agagggaagc caagtctcct ttggaaatag ctttagcaga aaaattagaa gcgcgtgaga
     4801 tggaactcta tcagcagagg tcaaaagcag aaagaaaact gacggatttg ctggattact
     4861 ataccttgtg ggtccatcag ataaagaccc ccattgcagc cagtcaactc ttagttgcag
     4921 aagtggtcga ccgccaactg aagcagcaac tagaacagga aattttcaaa atcgactcct
     4981 ataccaacct agttttacag tacctgcgtt tagaaagttt ccatgatgat ttggtcttaa
     5041 agcaggttca aattgaggac ttggtcaagg aaataattcg taaatatgct cttttcttta
     5101 ttcaaaaagg cttaaatgtc aatctacatg accttgataa agaaatcgtg acggataaaa
     5161 agtggctgct agtggttatt gagcaaatca tctcaaacag tctcaagtac accaaggaag
     5221 gtggtctgga gatttatatg gatgaccaag agctttgtat caaagatacg ggaatcggga
     5281 taaaaaacag tgatgtcctc cgagtatttg aacgtggctt ttcaggatac aatggccgtt
     5341 tgacccagca gtcctctgga cttggccttt atctatctaa gaaaatttct gaagaactgg
     5401 ggcaccagat tcgtatcgag tctgaggtcg gaaaaggaac gacagtgcgg attcagtttg
     5461 ctcaagtgaa cttagtcctt gagtaaaaat agatgagaaa aagcctccag attggaggct
     5521 tttatgctag actcttattt ctcaacgcgt gatttgttgg cgatatcagc taggatagct
     5581 tgaacaaaat tatcaactga gacagtttgt gtttcttttt ggccgtagcg acgaacgttg
     5641 actgtttcgt cttccatttc tttgtctcca acaattaatt ggtaaggaat cttgctggtt
     5701 tgtgaagcac gaatcttgaa ctgcattttt tcattgcgct catctacgtc tgcacggaca
     5761 ccgcggtcac ggagtttctt ggccacttcc caagcgtagt ccacgtgttt ttcgttagat
     5821 actgggatga gggttacttg gtgtggtgcc agccatgttg ggaaggcccc cttgtagttc
     5881 tcaatcaaga tagctgtgaa gcgttccata gttgagataa ccccacggtg gatcatgact
     5941 ggacggtgat cttcgccatc agctccgatg tatttgaggt cgaagcgttc tggcaacaag
     6001 aaatcaagtt ggatagtaga aagggtttct tcttttccaa gggcagtttt aatctggata
     6061 tccaattttg gtccgtagaa ggctgcttca ccttcggctt caaagtagtc cacgcccatt
     6121 tcatcaagag ctgcacgaag catggtttgg gcattttccc acatctcatc gttatcaaag
     6181 tacttatgag tatcttgagg gtcacgaaga gagaggcgga agcggtagtc agtcaagttg
     6241 aagtcttcat aaacatcgat aatcaactga agggcacgtt ggaattcttc ttggatttgt
     6301 tctggagtaa cgaataggtg accgtcgttg agtgacattt cacgtacacg ttgaaggcca
     6361 gtgagggcac cagatttttc gtaacggtgc atcataccga tttcagcgat acggattggc
     6421 aattcacggt aagagtgaac atggtgtttg aaaacttgga tgtggtgcgg acagttcatt
     6481 ggacgaagga caaattcttc cccgtcaccc atgtccatgg ttgggaacat gtcttcttgg
     6541 taatgatccc agtgaccaga agtcttgtaa agctcaacag aagcaagtgg tggagtgtag
     6601 acgtgttggt agccagaagc caactctttg tttacgatgt agcgttccaa ttcacgacgg
     6661 atagtcgcac catttggcaa ccagaatggc aaaccttgtc ccacttcttg tgaaatcata
     6721 aagaggtcaa gctctttacc aagtttacgg tggtcacgtt ccttagcttc ttcacgcatt
     6781 tgaaggtagt ttttcaagtc tttcttgtca aaccaagctg taccgtagat acgttgcatc
     6841 atagcgttgt cgctgtttcc acgccagtac gcaccagcta catggagaag gtggaagatt
     6901 tggatacgac ctgttgatgg aacgtgaggt ccacggcaga ggtctacata ttcaccctga
     6961 cgatagatag tcaaaccgcc ttcgtcttct gagtgttctt caatcaattc caacttgtaa
     7021 gggtcatttt tgaagatttc acgtgcctcg tctttagtca cttcttcacg aatagatggg
     7081 aagttttctt tgacgatttt ttgcatttct tcttcgatac gaggaaggtc ttcgttagag
     7141 atttgaccag ctgtgttgtc agtatcgtag tagaaaccat cttcgatggc tggaccaact
     7201 cccaagtgaa tgtctgggaa aagacgacga gctgcttggg cgaacaagtg agctgctgag
     7261 tgacgcaaga ttggaagggc atcttcgtga tcaggtgtca caatttcgat gcttccatct
     7321 tcagtgatag cgcgagtagt gtcgatgagt ttgccgttga atttaccagc caaggctttt
     7381 ttagctaggg aattgctgat agattgggca atttcaaaag ttgttacgcc agattcgaat
     7441 tcacgaacag cgccatctgg gaaagtaatg ttaatcatga tgttctcctt ttttattatt
     7501 tcatagtttc taagcattga ttttttatca gcagactact tccaagtcct aacgttcaat
     7561 tgcttttctt tatcagagag gaagttttcc atttccgtca gaatgtctat atccaaacgt
     7621 tgagaaagtt ctaatagcca ccagatattt tctgaaagtt tttgttccag tgtgtagggt
     7681 gtttcatcat agtagcgtcc ttgctttgtc atcaccagtc gttggaaatt tccaatatca
     7741 ttagataaag ccaagaggtc ttcttctacc gtccacttga aatcatgatg cttaacttcc
     7801 agttcgtgat aagcttgtcg gattgcccaa ctgcgctcca ctaattcttg caactccata
     7861 attagtatcc taataaaaaa atgcgacatc ctcgaaagga cgtcgcaacg tggttccacc
     7921 ttcatttatg tacctcaaaa gagagggaca cctctgatcg gctctaacgt ggccaccgtt
     7981 ttatgttttc ataaaaaact caagagtagt atcagtttag acttcctatg cgtttccagc
     8041 aaccacgcac tctctagtag aaagggacta agtgacttgt ctctatggat tattatagca
     8101 tgattgtgag atttttcaag gattttgtga aagttttttg tttttcatat tttgtagaat
     8161 atgcttgatg ctaataccag aatccatgcc caccagagca actgtttcat agattagcaa
     8221 gtaaattagt ataaactcac caaaggttat gatagtaaag taaaagagca gtccgttacc
     8281 aactaaccat caaagtgaga aacggaaacg gtagctatag agtaacgata caatcaagat
     8341 taccagaggt gtaaagaaga gaagattgtt tatatagtgt aaaggggtca gaaacaacta
     8401 gcaagaacaa ctcataaagt ggccaataaa agaataatat gaccagatag taggggagat
     8461 gggaatagaa tctacgcatg ataatcacct cgttttaaaa aaacagacaa cttagatctc
     8521 ttgctatgat tattatagca tgtttaaaac aagaaagtaa atttgttgac aaagaagatt
     8581 tttcttttca ctagaatcat agttagtttt cttggtagaa atattttgat aataattaag
     8641 caagactatt gatattgatt attaagagtg tcacatttgt tgtaactaaa ataattacaa
     8701 caatagaggt ataaaaaatg aaactagcag ttattgcagc aaatggacaa gcggggaaag
     8761 caattgttga agaagcagtc aaacgaggac atgaagtaac ggctattgtt cgttctgaaa
     8821 acaaaagtca agctgagtct attattaaaa aagatttatt tgagttgaca aaagatgatc
     8881 ttactggatt tgatgctgtt atttcagcgt ttggtgctta tacaccagat acgctaccgc
     8941 tccacagcaa atcaatcgaa ctatttaatc agcttcttgc tggaacacag acacgttttc
     9001 tagttgtagg gggagcagga agtctttata tagatgaaac aaaaacgaca cgacttttag
     9061 atacgtctga ttttcctgaa gaatttaagt cactagcaaa agctcaagcg gatgaatttg
     9121 atcttcttcg tacaaaaaat aatctcaact ggacttttgt cagtcctgct gtagatttta
     9181 ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg agaaattttt actactaatg
     9241 gaaaaggaat aagccagatt agttatgcag attatgctat tggattggta gatgaacttg
     9301 aaaaaggtca tcatataaaa gaacgtatct ctttacttga aaaataataa ctatgagagt
     9361 attaatgttt gacagaaaat ttaaatcttg gtaaaatagg gattgtcgta aagacaaata
     9421 acttcttctt ggttacaggc atgccaacct gtcactcgga tgaagccaaa taaaaaggag
     9481 aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc attgcacaat atgcacgtca
     9541 cgaaggtgat acaggttcag tagaggttca agttgctgtc cttacttggg aaatcaacca
     9601 ccttaacgaa cacatcaaac aacacaaaaa agaccacgct acttaccgtg gattgatgaa
     9661 aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt aaaaacgacg ttaaccgtta
     9721 ccgtgagttg atcaactctc taggacttcg tcgctaattc aagatacaaa ggccgtcaaa
     9781 agcacaaagc aaaaatagga aaattgacga agaaacttca gtttctagga gattttatct
     9841 tttttgccaa gtgcttaggc cgtgttcaat tgagcatatc ttgataataa agctactcta
     9901 aattgggtag ctttgttgcg ttgtcacctt acctcgctat actcaagtat aatcttcggt
     9961 tacggttcct agcactgtaa ggtaaaataa actagctttt ctcccttcgt ggagattttt
    10021 ttgtttcact gaaagtttcg tacgatcttc acctcgtccc ctagtctata aacgatttat
    10081 ctagcaagaa tcatgatgct aagggtgtca aaaatccgta tgaaaatagg gaaatgacac
    10141 agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc cgggctaaaa
    10201 tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca attttggaga
    10261 ctacaaaaat ctcaaatggt atcagctaat tacaccataa aggtgcgcag ctactcggct
    10321 tttcaagccg agtagctgta tgcaagcccc ctagaagagc ccactcttta caaagtaaag
    10381 tatagtatgt tatactttac atggaagtag tcactgaatt ccagttagaa attactttgt
    10441 aactacgttt tgaggaggag taaaatgctt tcctacgttc gacattaccc actagcgata
    10501 gctaaattaa tgtgtttgtg ctctcctaaa atctgctgat ttattactga ctaatacagg
    10561 aggttttttt tatgggacag acaatcatat ctgctattgg tgtttatatt tccaccagta
    10621 tcgattattt aattatttta attattttat ttgcacagct atcacagaat aaacagaaat
    10681 ggcatattta tgcggggcaa tatctaggca caggcttact tgtaggggcg agtttagttg
    10741 ctgcttatgt cgttaatttc gtgcctgaag aatggatggt tggattgctt ggtttaatcc
    10801 ctatctattt agggattcgc tttgcaattg ttggagaaga tgcggaagaa gaagaggaag
    10861 aaattattca aagattagaa caaagcaagg caaatcaact gttttggaca gttacattgc
    10921 tgacaattgc gtctggcgga gataatttag gtatctatat accttatttt gcttcgttag
    10981 attggtcaca gaccctcgtg gccttgcttg tgtttgtaat cggcataatt atcttttgcg
    11041 agattagtag ggtgttatcc tctattccgt taatattcga gacaattgaa aaatacgagc
    11101 gaatcattgt gcccttagta ttcattctac ttggactata catcatgtat gaaaatggca
    11161 cgatagagac ttttctgatc gtgtagattt ttttgtttca ctaggatttt agcctgagct
    11221 caaatcagct ctctgatttt cagagggctt tttcattgag tataaatgga caatcttaaa
    11281 gttactctat tgtagagtgg cttttgattt gattagggga ttcttataaa tatagtaaaa
    11341 tgaaataaga ataggacaaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta
    11401 gaagtagagg tgtactattc tagttccaat ctactatata aatgaaaacc ttagctgttt
    11461 ggccaaggtt catttcttct atgcaagttc ttctcttttc ttatctgggt tccagatgaa
    11521 gcttgcgata aagctaaaga tgatggttag gatagcgagg ataatagcaa ggatgagggc
    11581 agggatgcgg ataaaccacc agagtggatt tggtttttta tcattgtgcc attgtttcgt
    11641 ttcttcgtcc agacgttgga attctgtttg aatacgattg gcgactgttt caatgccttc
    11701 atcattcatt ttcttgatat ctgagatatc gattggattt ccaaagttca tatcgacacg
    11761 ttcacggcta atcaagccct tcaaagtcat gggaccggtg taggtaaccg gcatgatacg
    11821 gaccttggcc attttggcaa tcagtgctgc gccccccttg acatcgtttg agtggcggct
    11881 accacttgga aacatgatga gagagcggtc actttttttg agaacgttga taggatattt
    11941 gatggctgag gcgctgggat tttcacggtc gatgggaaag gcgccacaca tacgaatcca
    12001 ccaaccaaag atacggttgg taaagagttc tttttttgcc ataaagatga actgttttgg
    12061 cttggtcgca aaggccatat aaacaggatc ccaccaggta cggtgaggcg caactaaaat
    12121 ataattttca tcttgattag gaattttatc agtattatga tagtgagcat tgccattgat
    12181 ggaccataag agcaatacaa ctaatccacg caaataagta taaaacatgc gatctccttc
    12241 gattgttttc ttgttattat tataccttat caaaggaggg ctggcaaact tttcccttga
    12301 ctagatgcat atttgggatg aaattagaat tctgttaaaa aaaatgatat aatagaattt
    12361 atggataaaa ataagattat gggattaacc caaagagaag tcaaggaaag acaggctgag
    12421 ggtttggtca atgactttac cgcatcagcc agtaccagca cttggcaaat cgttaaacga
    12481 aatgtcttta ccctttttaa cgctttgaac tttgccattg ctttggccct tgcctttgtg
    12541 caggcttgga gcaatctggt cttctttgct gttatctgct ttaacgcttt ttctgggatt
    12601 gtgaccgagc tacgagccaa acacatggtg gacaagctca atctcatgac caaggaaaag
    12661 gtcaaaacca tccgtgatgg tcaggaagtt gctcttaatc ctgaagaatt agtgctagga
    12721 gatgtcattc gtttgtctgc aggagagcag attcctagtg atgccttggt tttggaaggc
    12781 tttgcggaag tcaatgaagc catgttaacg ggagaaagtg atttggtgca aaaggaagtt
    12841 gacggcttac ttttgtcagg aagtttccta gccagtgggt cagttttatc tcaagttcac
    12901 catgtcggtg cagacaacta tgctgccaaa ctcatgcttg aggctaagac cgttaaaccc
    12961 atcaactccc gtatcatgaa atcgctggac aagttggctg gttttactgg gaagattatc
    13021 attccctttg gtctggctct cttgctggaa gccttgcttt taaaaggcct gcctctcaag
    13081 tcatctgttg taaactcgtc gacagctctt ttgggaatgt tgcctaaggg aattgccctt
    13141 ttgaccatta cttcgctctt gactgcagtg attaagctag gtttgaaaaa ggtcttggtg
    13201 caggagatgt actctgttga gaccttggcg cgcgtggata tgctctgtct ggacaagacg
    13261 ggcaccatca cccaaggaaa gatgcaggtg gaggctgttc ttccactgac ggaaacttac
    13321 ggtgaagagg ctattgccag catcttgact agctacatgg cccatagtga ggataagaat
    13381 ccaactgccc aagccattcg ccagcgtttt gtgggagatg ttgcttatcc tatgatttcc
    13441 aatcttccct tctcgagcga ccgcaagtgg ggggctatgg agttagaagg cttggggaca
    13501 gttttcttag gggcacctga gatgttgctg gattctgaag tcccagaagc cagggaggcc
    13561 ttggagagag gatcacgtgt cttggtctta gctctcagtc aggagaaatt agaccatcac
    13621 aaaccacaga aaccatctga tattcaggct ctagccttgc tggaaatctt ggaccccatt
    13681 cgagagggag cagcagagac gctggactat ctccgttctc aggaggtggg actcaagatt
    13741 atctctggtg acaatccagt tacggtgtcc agcattgccc agaaggctgg ttttgcggac
    13801 tatcacagct atgtagattg ctcaaaaatc accgatgagg aattgatggc catggcggag
    13861 gagacagcta ttttcggacg tgtttcccct catcaaaaga aactcatcat ccaaacgttg
    13921 aaaaaagcgg gtcatacaac ggctatgaca ggggacgggg ttaatgatat cttggccctt
    13981 cgtgaggcgg attgttctat cgtgatggcg gagggggatc cagcaacccg tcagattgcc
    14041 aatctggttc tcttgaactc agactttaat gatgttcctg agattctctt cgagggtcgt
    14101 cgcgtggtca ataacattgc ccacatcgcc ccgattttct tgataaagac catctattcc
    14161 ttcctgttag cagtcatctg tattgccagt gctttactag gtcggtcaga gtggattttg
    14221 atttttccct tcattccgat ccagattacc atgattgacc agtttgtgga aggtttccca
    14281 ccattcgttc tgacttttga gcgaaatatc aaacctgtcg agccaaactt cctcagaaga
    14341 tccatgcttc gtgccctacc aagtgccctc atggtcgtgt ttggcgttct ttttgtgaaa
    14401 atctttggaa cgagtcaagg ttggtctgag ttagaaatct caactctcct ctattatctc
    14461 ttggggtcaa ttggtttctt atccgtattt agagcctgca tgccattcac tctatggcga
    14521 gtcctattga ttgtctggtc agtaggaggc ttcctagcca cagctctctt cccaagaatt
    14581 caaaaactgc ttgaaattgc aaccttaaca ggacaaacat tacctgttta tggtgtcatg
    14641 atgttggtct ttacagtgat tttcatcctg actagtcgct atcaagctag aaaataaaga
    14701 aagactgcaa tctgtggatt gcagtttttt atacgatgga tctatcgtag atctgatgtg
    14761 caaggcctac gtgtctatta tctatcggtg aacccaagag tgattctcaa gcctgcttgg
    14821 attgaggtaa tagattcaaa tatctgtagt tagactattt gaagtctgat gcaagaaata
    14881 attctcttcg aaaatatctt caaaccaggt ccgttctatc cacaatctca aagcggtact
    14941 ttgagcaact tgtggtcagc tccctagttt gatagtataa aaactgtcag ataaaggggt
    15001 ggcgaaattg tatctaaacg aacagaaacg tgatggtaag gcgtatagag ctcataggat
    15061 ggcaaggaaa gtctagaacc taaaaaagaa ctagataaat ccactaagtg tggttactct
    15121 agttcttttt cgtttattca acacccaaga tttctttaat atcatcaacg ctcagattgc
    15181 ttctgctttc ttgtccttca aggacggtgt tgaagagttc ctttttactt tcttggagtt
    15241 cttgtatttt ttcctctatg gtaccaagtg tgataaggcg atagacatcg acttgtttgg
    15301 tctggccaag gcggtggctt cggccgatgg cttgcatctc aactgctgga ttccaccaga
    15361 ggtcacagag gatgacggta tcagctcctg ttagattcag tcctgttcca cctgctttta
    15421 gggaaatgag gaagcagtct ttttcccctt gattgaaaag attgaccatt tcttgacgtt
    15481 tatctgaagg tgtttgtcct gttattttaa agtgagacat ttcttttttc tctagttctt
    15541 gctcaatgag atcaagcata gaggtgaatt gtgaaaagat aagtggtcgt gacccttttt
    15601 cacgaatggt gtctaggagc tcgaataagc tgtccatttt tccactatcc cctttgtagt
    15661 cttctaaaaa gagagcaggg gtattacaga tttgtctaag tcgggtcagt cctgctaaga
    15721 tttcaatttt atgacgttta atctcatagg cgctggctcc tgaaaccatt tcttgcatgc
    15781 gtcgaagttg agctagatag agcgtttttt gcgaactgct gagttcattg ctgtagaggt
    15841 gctcgctcag ttcaggcaat tctgtcagaa cttcgtcttt tttcctacgc agaacaaaag
    15901 gttgaatcag tttagcaacg agttgaggtg acaattttga aaattccttt ttacttggta
    15961 ggagacctgg taatactatc tggaaaatag accaaatctc ttcgagacgg ttttcaatag
    16021 gagttccaga tagggcatag caggttttga catcaaattc tcttaaagct tgtgctgttt
    16081 tggtctgact attttttatc atctgtgctt catctaggat gaggtagtcg taagactgct
    16141 tttgataatg ttcaaggtca gatcgaaaag atggatagct tgtaatagtg atagtagcag
    16201 atttttcaat ttgtttgata cgctcagttt tgctaccata ggctacttca acctgtttgt
    16261 gaggcacaaa ttttcggaat tcttccttcc aattataaag aaggctggct ggagctagga
    16321 taagagcttt ctggtctggt ttaaggttgg cttccagaag agtgatggtt tgcaaggttt
    16381 tccctagacc catgtcgtct gccaggattc ccccaaaatg ataatgatcc agcatactca
    16441 gccacttgac tccttctttt tgataggagc ggagtttggc cttgacttca taaggcttga
    16501 tatcaaattc ttcagggtgg gtcaggtcat aagccatctt tttgaaatca cgagaaaaat
    16561 tgacatgttc attgtctttg aaggtttcag aaaggctaaa ggcacgagat ttgtgcatct
    16621 tgatttttcc gtctgaaaat ttagcgcgaa gatcttggag actttgagca accttgagac
    16681 tttcatcgtc aaagactaga acctttcctt gcttggtttg gtagtggctt tcttgattcc
    16741 ataaagcttg gatagctttt tcaacctcat cttctgaaat catagaaaaa tcaaactgaa
    16801 ctgaaaggaa gctttcgtcg tcaaaaatgt caatgacagc aggatcttct actaagagtt
    16861 tttcaagcga ttcatctagt tgaacttgac ccagagtacg aaaacggggg agttctttta
    16921 ggaagaaatc aacgattttg attttggaaa gactatgaaa ttcctctttg aaaccagcag
    16981 aaagcagttg atgatagatt tttctagctt tgctagcttg gtaagtatag gggagggtta
    17041 ggagatcttg tttagaatgg acttgttttt ctccaaagga ccacaccata ttaagggcaa
    17101 tttcatttct agtcttggag aaggcaaagg tggggataaa gtcatggatt tgtaattcat
    17161 ctgggatact gataggaaca tagtttgaga tgatattaca gacttgcatg agttaagcct
    17221 tattttcttt tgaaaagata agaggagaat tttcttgata atgatagatc caagtagcta
    17281 atttatccaa aaagtaacgg tgttcttctt tgatgatgtg gaagtgattg tgtcgaatcc
    17341 aaagtttttc ttgaataatg aaaccaaaat aagctgtatt gatgatttca taatggttat
    17401 tagatttgac aactttaaaa atttcctctt ccgggataaa gggactatca tctaagaata
    17461 taagagggta ttcggctttt gaggttacat attggaagac atccaaagct tgaaaaagtg
    17521 ggacgaggtc gtttaaatag ctaacaggag tctctaaata gcgtccgtaa tctctagggt
    17581 taatgccata actgaagttg aaataagaat gttcatttct atcgataaaa tattttttaa
    17641 tatagaggag taggttttgg gatgcttgat taaactgatt caaggataat ctgattgtcc
    17701 cgattttctg tgaaacaaag taatcttcct tttggaaaat gagaaaaatg aagtgagcta
    17761 tatccttgat aacataggca cgaggagctt gttctacctg taattttaag gtccaggcta
    17821 ggctatgatt tcggatttcg acttgtccat gaagggcaag tgaaggcgcc gtagcttttt
    17881 cttctaccag ttcatcttgg agctcttcag atggcaaggt aggaatcagt tggctggcaa
    17941 aacttggttt atgactcgct ttaccaatgc gttcttgaat agcttggggg agactacgaa
    18001 aataaagatc catggcaacc cagtgtttac agactccctg attttggaaa tccttacatt
    18061 cgcaatgaaa gccagtcaaa tcgaagtgct ccatactggt caggatgttg ggctccagat
    18121 gcatggaaat accatcatag gtattggggt gcttaaaata ttccttattt tcagtatcaa
    18181 aatagttttt tatctgttgg aaaatagagc ggccatccat tctcatacga gcaggtagtc
    18241 tatcgggaac cgtcattgaa gtaacctctg ttctaatcat tcttttctct atcttatcag
    18301 aatttatagg aaaagaatag atttatctta cataaattgc atcttgatag ggattggaaa
    18361 catttgtagt tgcaagatag ttgtatgtaa tatcgacaat caattacaag gagattacga
    18421 ttccatagaa actatcaagt gaaaactgac ttatccataa cattctagct aaacttcttc
    18481 ttggtttggt aagtttttca tctggtgaac tagataggct gctataagta gtaaaattat
    18541 aagagcaaaa gcaacaactt ccagaccagc acttgttgca agaaatacga gagcaaggga
    18601 taggacagct gggataagta agttgataac attgatggat gattgaactg atcccattaa
    18661 ctcctcagga atgattccaa aaatcatggc ttgcaagcga ggactcaata ctcctgccga
    18721 gaaagcatca cccgcacttc ctagtaaaat aagtaaaaaa cttccacgta gaaaatctat
    18781 aacaatgaga gactccatca atagactcca ataaatattc aggcgaatag aaattttttt
    18841 agatagaaat ccactcagaa gtccacctaa aataacatga agaaggctta tcattattaa
    18901 aattgccaga ctttgccctg ttgacaaacc cataaaagga tggtgaatca gtagaatcgc
    18961 actgacaggc tctaccatca tcaaaacagc ttgactaatg gacaaaatcc aaagcaagac
    19021 catgacatct tccatagtca tcaataattt cattgactct ttcaaatgct ggaaaaagct
    19081 actcattcct acataaggag gaacttcgat tttttcttcc tcttttttca agcggtttcg
    19141 gataagtaga cttcctagaa aggcaaataa aaaggttaaa acatttacaa aagctagagt
    19201 agaaatgcta aacagtccta aaaatactcc tccgctgaga ttacctatca aacgtacaat
    19261 ggaactcgtg gactgcctaa aacccatagc ctccgtcata tcatcgttta ttagtcgtat
    19321 gtaaatcggt gtcagcatgt atcctgcaag aaaaccaatc gtatctgaaa tcaagttcat
    19381 gctgcaaata aagaaaacag aaaagagaga gaagtcggta cttgtcagga gcaaagtcac
    19441 tccagaataa aggaggacct tgataaagag gatagaaata tacttgctga ttcgattttt
    19501 ttgaaaatca gctataactc cagtaaaaag ttgcaagacc tgtggaatgg tttctgatag
    19561 gctaatcaaa aatatagcta agggagcaaa ggcataagaa gagacataat tgataaaagc
    19621 taagtaaaaa atagtatctc caaaacttga aatccactca tttactgtta gctgacgaaa
    19681 agctcgattt ttaagaaaaa tatgcatatt aatctccttt acttaattca aatgggaatg
    19741 tataaccgag taaagtccaa taaataccca gatttcccac accaaagtca aaataactgt
    19801 ttattccatc ttccccttga aattgtaata atctatcatt attacgataa gaacgagtca
    19861 ataagatttt ttttatgaac tgttcaacct tttgattttt attgtatatt gttgtttgca
    19921 ataaactact taaaccatgg caaaaactag ttcccattgc ttcatattgt tgcaccattt
    19981 caagttgtga tttatagatt atctcagagt atctttcttt atcaatcaaa caaagataca
    20041 atattaatcc tgaaactccg tcacaccaag aaagacctaa attatctaat ttagaaaagc
    20101 ttgaaagttt ctcttctagt aattcagata tcccgtcaga aaatttttgt aaatgatttt
    20161 gatagcgact atctccaaaa atatcagtat aggcttttaa tacataggca gcacctgaac
    20221 gtccgtgagc aaaattatta gaatatatat ctccattatc ctcggattct aataaactat
    20281 atgcatcatt tatattgttc ttgataaaat ttgctagttt tttatcatca aaaatggtac
    20341 aatatttcat caaactgagt aggataccag acttccctaa agcaaaatct aagttactaa
    20401 tattgtcata aacccgcatt aaatgatcga ctaatctctt acttatgtct attaaatatc
    20461 tctcctttgt tttttcatac ctatctagga ttccaaatag gaaacctgct ttcccaaata
    20521 gtagagagta accatgtaaa aaattagctg cttcataatt ttctaatttc gtaagccatt
    20581 ctttaacggt attttcatct tcctcaacat aatatttatt cataaaaaat aaaactcctc
    20641 caaaaccatg ttggaaagaa acaggactta cgaactcacc aaattcattt gacggaaaca
    20701 aacgaccaga tttgtccata gatttagcca gtaagtatga ttttatattc tcagcctcct
    20761 ctttaaaatt atatttttca aaataacttg aaaaatctgg agtatttaaa agaatgtcac
    20821 ttgtaacttg tttcaattgc tttatttttt ggattttttc tccctggctc atcattaata
    20881 aatcgtatag ccagtattct tgttgtttag ttattttatt gtctaatcta gctattttta
    20941 ttagatgaca tatttttata aaggccgata atcctgtttt ttgatcacct tttgaaaagg
    21001 ataaaaaatc acctgttaat aaagaaaatc caattagtgc taaactaaaa taatcttgtt
    21061 gaactgagct gatagttagg tcagtatctg gattaaccat cattggtgtt ttaactcgtc
    21121 ttaccttatc cttgatagga gtcattgtct ccaagtctat taatgttata tcaccttttt
    21181 tggtatatat aaaatttgta ggagctatat ctacaatttt atattcccag tttatggatg
    21241 taacttacta tattcacaat gttatccagt gttttttctc taatatttaa ggagtgttct
    21301 gtttctcgaa taaattcttc aaagtttaac ccgtcaactt gttcctgaac aagaaaataa
    21361 tcatccacga tataaaattc atcagttaaa ttagtagtat aacttttatc ggctaatttt
    21421 tttagcatgt gagcttcatt ttttatatca tcaagagctg tccattctcc ttcagcatca
    21481 taattcacaa aaggtcttga ctgcttgatg attacttttt gcccgtccga ttttctaatt
    21541 gcccgataaa catttccttt atttgatctc ttaataattt tttccatttt gtatttattt
    21601 attgcagagt ccttacttga aacttcacat gtggtttgaa aataaatcct tttttcttct
    21661 tctgaaaata aatccatttt ccagctagga agactaggga aattttgtct cttatcttct
    21721 acatagttct tccttttttc atctagcaat aaatagatga cttttttatt tttttcatca
    21781 taagcttgtt tttttaaaaa agccccatat ctataatgaa ctggagaatg cattccacat
    21841 tgatagtcag atagtatttt tggagcctta aattctgaca gtctattcgt aagattacaa
    21901 atcatactct tagcttcaga ttctgactta ggatatagag ttataaattt gttagcagta
    21961 gggctcattt ccctagggga attaattttt tttaattcct ctaaattttt aacaacttta
    22021 aagctacaat tatttagttg ggatagttta tacacaatct taaaaatatt tacagcgtct
    22081 tttatttggg agcttatgtg tattttccac ccttgtgcag gcatcttatc tgataaataa
    22141 tagtaattcc aaatatcacc ctgttggaaa tttttatcac attttaaaca ttctttctct
    22201 aataaatcca taacaaactc ctaattatta aaataggcta gagacacagc actagcctat
    22261 tccgtaagta aagctactta ttttatataa aatataacta gcgacctgta attaaacaag
    22321 taaaagaaca atacttaggg agacctgtga caatgatatc ttcctctgga agtagttcta
    22381 attcaaacaa tgtttgttcc atgactgtat cctcctgtta tgataaattc cagaaagcat
    22441 agagcaaatt cgtggttcgt ctgactaaat ttcttatctg aacaccacct tcaaatacaa
    22501 attttagtca aacttttatt ttttctaact ttctaattat attctaccat gtgtttttat
    22561 atgtcaagaa ttttctgaat aaactgttta ttttttattt tttgacattt ttgcaaattg
    22621 tttaaaatct ttcaattgga ttcacttatt actttaggac attgaaactt ctttcgccag
    22681 aggtgcttat attactggga agttgaagat tgaaatgtgg tataataaga ggtaatagag
    22741 ttttggaaag tgagagaaga tgatttcaaa gagattagaa ttggtagctt cctttgtgtc
    22801 acagggggct attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt
    22861 tgagagaggc caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc
    22921 tgcggttaaa aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa
    22981 tggcttggca gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg
    23041 tggtcgtttg attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg
    23101 tttgatcctc cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg
    23161 attccagatt gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt
    23221 ggtggaagca ggacaaatga agctatcagc cagtgatgtt cgctttggac cgttcttgtg
    23281 caaagaggtc agtccagtct ttgtccaaaa atggcaaaaa gaagctgtta agctagagtt
    23341 tgccctcgga caaatcccag acaaaaatct ggaagaacgt caagttctag tagataagat
    23401 tcaagccatc aaggaggtgc tccatgttag caagtgaagt gatccaagct tatgaagcct
    23461 tttgccctca ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag
    23521 acaagggtat ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg
    23581 ccattgaaaa gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca
    23641 aggacttgct tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgaca
    23701 tcgcagttta tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt
    23761 tttgtcagat gctagaaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg
    23821 gaattggacg tattgggaat attcagcctc agacctttgg agaattggcc caacatgtca
    23881 agcaagtctt tgacctagat agccttcgaa tggtgcatta tcaagagaat gatttgcaga
    23941 agcctatttc aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt
    24001 tggcaaaggg ggcagatgtc tatatcactg gtgatatcta ctaccatact gctcaggata
    24061 tgctgtctga tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg
    24121 aaaaaatcgc agcactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt
    24181 tacctagtca agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg
    24241 aaaaaagttg ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg
    24301 agagaaagtg acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc
    24361 gcagcaggaa ttatcagtcc ttggttttcc aaacgccgta ataaagcctg gtacaagatg
    24421 gcgcgcttgg gggctgattt ttatgtggat ttattagctg atttagagaa atcaggacaa
    24481 gaaatcgact tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaatttg
    24541 gaagaacttt atcaactggc cctccagcgc agagaagaat ctcccttgat agggcaatta
    24601 gccattctga accaagcctc agctaatgaa ttattccctg gtttgcaggg atttgaccgc
    24661 ctgctctatg cttctggtgg agcgagagta gatggccaac tcttggtaac tcgtctgcta
    24721 gaagccagtc atgtcaagct ggtcaaagaa aaagtgactc tgacaccgtt agcatcaggc
    24781 taccagattg gtgaagagga gtttgagcag gttattttgg cgacgggagc ttggttgggg
    24841 gacatgttag aacccttggg ttatgaagta gatgttcgtc ctcaaaaagg acaactacga
    24901 gattatcagc tggtccaaga tatggaagct taccctgttg tcatgccaga aggggagtgg
    24961 gatttgattc cttttgcagg tgggaaattg tccttaggcg ctacccacga aaatgacatg
    25021 ggatttgatt tgacggtaga tgaaaccttg ctccaacaaa tggaggaggc caccttgact
    25081 cactatctga ttttggctga agctacttca aaatctgagc gtgttggaat ccgtgcctac
    25141 accagtgatt tctctccttt ctttgggcag gtgcctgact taactggtgt ctatgcagcc
    25201 agtggattag gttcatcagg cctcacaact ggtcctatta ttggttacca tttagctcaa
    25261 ctgatccaag acaaggagtt gaccttggac cctgaaaact acccaattga aaactatgtc
    25321 aaacgagtaa aaagcgaata atactcaatg aaaatcaaag aacaaactag gtaactagcc
    25381 gcgggttact caaagcactg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa
    25441 cactgttttg aggttgtaga tagaactgac gaagtcagta accataccca tggcaaggcg
    25501 acgttgacgt ggtttgaatt ggattttcga agagtataag cattttactg aaattttatc
    25561 aggtagttta ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa gaaaaaataa
    25621 tctgagaatc gaggaaaaaa gatgcaagaa aagattttgg taactggtgg tgccggtttt
    25681 attggaaccc acactgttat tgaattgatc caagcaggcc atcaagttgt tgtggtggat
    25741 aatcttgtca atagcaatcg taagagttta gaagttgttg aaagaattac aggagttgag
    25801 attcctttct atgaggcaga tattcgtgac acagctaccc tcagagatat tttcaagcag
    25861 gaagaaccga ctggtgtcat tcactttgct ggtttgaagg ctgttggcga atcaacacgt
    25921 atccctcttg cctactatga caacaatatc gctggaactg tcagcctttt gaaagccatg
    25981 gaagaaaaca actgtaaaaa catcatcttc agttcttctg cgacagttta cggggatccg
    26041 cacacagtgc ccatcttgga agatttccca ctttcagtga ccaacccata cggtcgtacc
    26101 aagctcatgc tagaggaaat tttgaccgat atttacaaag cagactcaga atggaatgtt
    26161 gtcttgcttc gttactttaa cccaatcgga gcccatgaga gtggtgattt gggagaaaat
    26221 ccaaacggta ttccaaacaa tctcttgcca tatgtgactc aagtagccgt tggaaaatta
    26281 gagcaagtgc aagtgtttgg agacgattac gatacggaag atggaacagg tgttcgtgac
    26341 tatatccacg ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa
    26401 ggttcaggac taaacgttta taaccttgga actggtaaag gttactcagt tcttgaaatt
    26461 atccaaaaca tggaaaaagc ggtgggacgt cctattcctt accgtatcgt agaacgtcgc
    26521 ccaggtgata tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga actcggttgg
    26581 gaagcagaac tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat
    26641 ccaaatggat ttgaagacta agatgatgat ttcaatcatc gtcccttgtt taaacgaaga
    26701 ggaagtactt cctctttttt atcaggctct ggaagcttta cttccagatt tggaaacaga
    26761 aatcgagtat gtctttgtcg atgatggatc aagtgatggg accttggaac tcttaaaggc
    26821 ctatcgggag caaaatccgg cagtccatta tatttctttc tctcgaaatt ttggcaaaga
    26881 agcagccctt tatgcaggct tgcaatatgc gacaggagat ttggtggtgg tgatggatgc
    26941 agacctccaa gatcctccta gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt
    27001 agacttggac tgcgttggga cacggagaac tagtcgggag ggagaaccct tctttcgcag
    27061 tttctgtgct gttctctttt atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc
    27121 gggtgtccgt gattttcgta tgatgagaag gtctgtagtc gatgccattt taagcttgac
    27181 cgagtccaat cgtttttcaa aggggctctt cgcctgggtg ggtttcaaaa cctactattt
    27241 ggactatcca aatgtcgaaa ggcaggctgg caagacaaat tggagtttta ggcaactctt
    27301 tttctactcc attgaaggga ttattaattt ttcagatttt cccttgatta tagcctttgt
    27361 agctggtctc ctatcttgtt ttctttctct gctgatgacc ttttttgttg tggttcggac
    27421 cctcattttg ggcaatccga catctggttg gacctctctg atggctgtta ttctctttct
    27481 tggaggtatt caactcttga ccattgggat tctcggcaag tatatcagta agatttattt
    27541 agaaaccaaa aaaagaccgc tttatcttat caaagaaaaa agttatcata gatcatgaaa
    27601 aagtaggagt tatctagcgc agtcactttt ttgtaattat aattcttttg gtctggaact
    27661 tgagtgattt ttaaaaaaat tagggatttg acatgatata aatgaactat gtggaataaa
    27721 tttactgcaa agacgataac ttaataaata aaaaattcag gagggttatt ttatgctaag
    27781 taaagaggag tatattgaag aaatcgggct tatagagaaa caaaattatg tagaggttga
    27841 actgtatcct ttagttgctg atataattaa tccgacttta aaaaatagtt tatcaaaaag
    27901 atatgtcttc ggaagaagaa agagtaatat ggggcaaata tattatggtc taagtaattt
    27961 tcctgatata gttattttgg ataagaatta tcaaaataaa gccagaaaaa gtatagaaat
    28021 tgaagaatgg aagaaacttc gaggatgcgt ggaaattaag agtttaaagc atgatttaat
    28081 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    28141 gggacaactt attggagacc ttttatggta taaaaaagta atttatacaa atggaattga
    28201 atggagattt ctaagtttag atgacaagga agagatagat aatacaattg ttcaagtagt
    28261 taacaaaaga atagaaacag aagaagcggg aaattctttt gattggtgga agaatattaa
    28321 agatttatcg ttcaattata cggatatata tttatctaaa gattgtatac aagagtggga
    28381 tgaatttgta aagaaagtaa aggaaataga atggtaggag tctattctca ttgagaaatt
    28441 tagattataa gtcgcagtaa gatttattta gagactaaaa aaagaccact ttatcttatc
    28501 aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata aagtgaaaag actataattt
    28561 tacatggaaa tgtgctaaac tagagggagt ggattatcgc cattgattta ggcttcctgg
    28621 tttccaatca gggcgcgagt tgggcaattt ttaacagcct ctaagatatc ctgactagga
    28681 gaaatttctt tttccagttg gtcagggtca tcgtaaaaac gcacgattcc attatcgtgg
    28741 taatcaaata aatcagaata agtttggcaa agcccacagg cgatacatcg ttcaggtata
    28801 agtgtgattt tcatgttcat atttatattg taataagaaa agtaaaaaaa aacaaggagt
    28861 aaggtatggc aaaagaaccg tggcaagaag atatctatga tcaagaagaa tcaagagcag
    28921 agcgtcggca tcgaaaccac ggaggggctg ataggatggc taatcgtatt ttgacgatcc
    28981 tagctagtat tttctttgta attgtggtgg tgatggtcat cgttctcatc tatctatcat
    29041 cgggggggag taatcgcaca gcagccttaa aaggctttca tgattctgat gcaagtgtag
    29101 tacaaatctc atcttcaagc agttctcagc ctgagcagag ttcagagcca gaatctactt
    29161 ctagtagttc agaagaagct gctaatcctg aaggaacgat taaagttctc gcaggagaag
    29221 gggaagcagc tattgccgct cgtgcaggaa tctccattgc tcagttagag gccttgaatc
    29281 ctgggcacat ggttacagga tcttggtttg ctaatccagg tgatgttata aaaataaaat
    29341 aggagccgat atgaaaacaa ttcaaattgc tattgatggt cctgcttcca gcggtaagag
    29401 tacggtcgca aagattattg ctaaggattt tggattcacc taccttgata caggagctat
    29461 gtatcgtgca gcgacctata tggctcttaa gaaccaatta ggagttgaag aagtcgaagc
    29521 ccttctagcc ttgttggacc agcatccaat cagctttgga cgttcagaaa ctggagacca
    29581 gcttgttttt gtaggagatg tggatattac ccatcctatc cgtgaaaatg aagtgaccaa
    29641 tcatgtttct gctattgcag caattcctga agtgcgtgag aaactggttt ctctccaaca
    29701 agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc gatattggaa ctgttgtatt
    29761 gccacaagca gaattgaaaa ttttcctagt agcttctgtt gatgagagag cagagcgtcg
    29821 ttacaaggaa aatattgcca agggaattga aacagacctt gaaaccctaa aaaaggaaat
    29881 tgctgcgcgt gactacaagg atagtcatcg tgagacttct cctctcaaac aagcagagga
    29941 tgctgtctac cttgatacaa ctggtttgaa cattcaagaa gtagttgaaa aaatcaaagc
    30001 agaagctgaa aaaagaatgt aaatgtagaa aagccgatag attgatatcg gtttttttct
    30061 aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa ttttgatttt
    30121 caaagaatag tgaatgatga taaggagaaa ccatgaacaa tttaccaaat tgtccaaaat
    30181 gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag tgtgctcatg
    30241 agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc gatgccaacg
    30301 gaaataaatt gactgatggt gatacagtaa ctctcatcaa ggacttgaaa gtaaaaggtg
    30361 cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccgcatcgta gaaggcgacc
    30421 acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca gagtttgtga
    30481 ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta tcttcttgtt
    30541 tctagcggct tttacgggag tttatcttga aattactaag catggtggtt ttgggatgct
    30601 tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt atcttctaaa
    30661 ggttatgagc cgtgtaggtg aaaattggca aaggccaagt ctcttgcgct taaaaggtgg
    30721 ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg cgcccattgc
    30781 gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca tctggttttt
    30841 agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc cagcagtgtg
    30901 gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg ttctaaaact
    30961 caatattcca aatgctaagg ataatccttt cccttacttc tttttgaatg tgaacaaggg
    31021 ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg tagcaggatt
    31081 tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt cgaaaatctc
    31141 ttcaaaccac gtcagcttcc atctgcaacc tcaaaacact gttttgaaca acctgcggct
    31201 agcttcctag tttgctcttt gattttcatt gagtataaga tacaagggat tcattttcga
    31261 atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat ttgataacta
    31321 tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca atttttagaa
    31381 cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat ttcgagtgcc
    31441 ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga gctcttggtg
    31501 agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt agaaaaaata
    31561 tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag cggtacagct
    31621 cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt tggtttgggt
    31681 cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca aggaaaaagg
    31741 cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc tctcattacc
    31801 ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc ctatagtgct
    31861 ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc aaagaaagaa
    31921 gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg cttgattttt
    31981 accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac catccgtatt
    32041 ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt tgttcttagt
    32101 atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat ttctatcttt
    32161 aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat cgtgattgcc
    32221 ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt tgcctatagt
    32281 gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa actcctcaat
    32341 caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac cccatttgtt
    32401 ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat cttaggaggt
    32461 tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc ttaggattga
    32521 ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcatagttga ttgagtttgg
    32581 aatagtacgc tgtagctgct aaaatatttc tagaaattaa tttgactttt ctaatagagt
    32641 tattcatatc ttatttcaat ctactataga aagctagccg caggttgctc aaaatagtgt
    32701 tttgaggttg cagatggaaa ctgacgtggt ttgaagagat tttcgaagag tatgagattt
    32761 ttatacccat acaatatttg ttttaggtcc ttgtttacag actaatttct tgataaaata
    32821 gaggttatga cgagatataa agcaactatt tcctatgatg gttatgcctt tgctggcttt
    32881 cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg aaaaaacctt gaccagatta
    32941 aataaagggc aaaccattac tgttcacggt gctggtagga cagatagtgg ggttcatgcc
    33001 ctgggacagg tcattcattt tgacctgcct tatcagatgg atgaggagaa actccgtttt
    33061 gccttggata cccagtctcc tgaagatatt gatgtgattt cgattgagct tgtggcagat
    33121 gattttcatt gccgttatgc caaacatagc aagacctatg agtttattgt ggatagagga
    33181 cgtcccaaaa atcctatgcg ccgtcactat gccacccact ttccctaccc actcgatgtg
    33241 gaacgaatgc agattgcaat caaaaagcta gagggaaccc atgattttac cggttttaca
    33301 gcctctggga ctagtgtaga ggataaggtt cgcaccatca cagaagctag tttaatagtc
    33361 gatgagacag gacaattttt gacctttacc ttttcaggaa atggtttctt gtataaacag
    33421 attcgcaata tggtggggac tcttctcaaa atcggtaaca accgcatgcc agtagagcag
    33481 attgatctca tcttggagaa gaaggacagg caacttgcag gtcccactgc agcaccaaat
    33541 ggtttgtatt taaaggagat tcgttatgaa gaataatcgt attttagcac tttctggaaa
    33601 tgatattttt agtggtggtg gactgtcagc tgatttggct acctatacct tgaacggctt
    33661 gcatgggttt gtagcagtga cttgtttgac agccttgaca gaaaaaggat ttgaagtctt
    33721 tccaactgat gataccattt ttcaacatga attagatagc ttgcgtgatg tggaatttgg
    33781 gggaattaag attggtcttc tccctactgt cagtgtggct gagaaggcct tggactttat
    33841 caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc ttggtctgca aggaaacgca
    33901 tgatgtagct gtcagtgagc tctgccaaga gttgattcgc tttttccctt atgtcagtgt
    33961 gattacgcct aatctcccag aagcagaatt attatccggt caggaaatta aaaccttgga
    34021 agacatgaaa actgcagcgc agaaattgca tgatttagga gctccagcag tcattatcaa
    34081 gggaggcaat cgtcttagtc aggacaaggc ggtggatgtc ttttatgatg gacagacctt
    34141 tactatccta gaaaatccag ttatccaagg ccaaaatgct ggtgcaggtt gtacctttgc
    34201 ctctagcatt gccagtcact tgattaaagg tgataaactt ttgccagcag tagaaagctc
    34261 taaggctttc gtttatcgtg ctattgcaca agcagatcag tatggagtaa gacaatatga
    34321 agcaaacaaa aacaactaaa atcgcccttg tatccctatt aaccgccctt tctgtggttc
    34381 taggttattt cttaaaaatc ccaacaccta caggaattct aactctttta gatgctggtg
    34441 tcttctttgc ggccttttac tttggtagtc gtgaaggagc ggtagtcgga ggactagcaa
    34501 gtttcttgat tgacctctta tcaggctacc ctcagtggat gttctttagc ttggtcaacc
    34561 atggcttgca gggatttttc gcaggattta aaggaaaaag tcagtggtta ggccttattt
    34621 tagcaattat tgccatggta ggaggctacg ccttgggttc tactttgatg aatggctggg
    34681 cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa tatggtaggg atgattgtag
    34741 gatttattct tagtcaaagt atcaagaaga ttaagtaata ctcttcgaaa atctcttcaa
    34801 accacgtcag cttccatctg caacctcaaa ccactgtttt gagcagcctg aggctagctt
    34861 tctagtttgc actttgattt tcattgagta taaagaggtt gagtaaaaag tatttcaaat
    34921 aagaaaaacg catagtatca ggtgttgaat gaactgcccc ccaaaagtta gacagaaaaa
    34981 atctaacttt tggggtgttt tattatgaaa ctaacttatg atgataaagt tcagatctat
    35041 gaacttagaa aacaaggata tagcttagag aagctttcaa ataaatttgg gataaacaat
    35101 tctaatctta ggtatatgat taaattgatt gatcgttacg gaatagagtt cgtcaaaaaa
    35161 ggaaaaaatc gttactattc tcctgattta aaacaagaaa tgattaataa agtct
//
LOCUS       DAVLHM010000023        34760 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLHM010000023 DAVLHM010000000
VERSION     DAVLHM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.023"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            146..310
                     /locus_tag="VXE45_001168"
     CDS             146..310
                     /locus_tag="VXE45_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0789201.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            394..960
                     /gene="amaP"
                     /locus_tag="VXE45_001169"
     CDS             394..960
                     /gene="amaP"
                     /locus_tag="VXE45_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0789202.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            972..1142
                     /locus_tag="VXE45_001170"
     CDS             972..1142
                     /locus_tag="VXE45_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0789203.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1181..1789
                     /locus_tag="VXE45_001171"
     CDS             1181..1789
                     /locus_tag="VXE45_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0789204.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1820..2023
                     /locus_tag="VXE45_001172"
     CDS             1820..2023
                     /locus_tag="VXE45_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0789205.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2118..2396)
                     /locus_tag="VXE45_001173"
                     /pseudo
     CDS             complement(2118..2396)
                     /locus_tag="VXE45_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2594..2881
                     /locus_tag="VXE45_001174"
     CDS             2594..2881
                     /locus_tag="VXE45_001174"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0789206.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3159..3929)
                     /locus_tag="VXE45_001175"
     CDS             complement(3159..3929)
                     /locus_tag="VXE45_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0789207.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3944..4792)
                     /locus_tag="VXE45_001176"
     CDS             complement(3944..4792)
                     /locus_tag="VXE45_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0789208.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4789..6264)
                     /locus_tag="VXE45_001177"
     CDS             complement(4789..6264)
                     /locus_tag="VXE45_001177"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0789209.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6587..7942)
                     /locus_tag="VXE45_001178"
     CDS             complement(6587..7942)
                     /locus_tag="VXE45_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0789210.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7952..8269)
                     /locus_tag="VXE45_001179"
     CDS             complement(7952..8269)
                     /locus_tag="VXE45_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0789211.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8286..8603)
                     /locus_tag="VXE45_001180"
     CDS             complement(8286..8603)
                     /locus_tag="VXE45_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0789212.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8616..10301)
                     /locus_tag="VXE45_001181"
     CDS             complement(8616..10301)
                     /locus_tag="VXE45_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEV0789213.1"
                     /translation="MKNKKLILSLFILFLLIFIHAKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(10306..11202)
                     /locus_tag="VXE45_001182"
     CDS             complement(10306..11202)
                     /locus_tag="VXE45_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0789214.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(11205..12467)
                     /locus_tag="VXE45_001183"
     CDS             complement(11205..12467)
                     /locus_tag="VXE45_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0789215.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            12747..13925
                     /locus_tag="VXE45_001184"
     CDS             12747..13925
                     /locus_tag="VXE45_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0789216.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(14153..14599)
                     /locus_tag="VXE45_001185"
     CDS             complement(14153..14599)
                     /locus_tag="VXE45_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789217.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVQKYSRLKLE"
     gene            14669..15328
                     /locus_tag="VXE45_001186"
     CDS             14669..15328
                     /locus_tag="VXE45_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0789218.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACGIIFGKLLL
                     V"
     gene            complement(15380..16531)
                     /locus_tag="VXE45_001187"
     CDS             complement(15380..16531)
                     /locus_tag="VXE45_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0789219.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(16546..17277)
                     /locus_tag="VXE45_001188"
     CDS             complement(16546..17277)
                     /locus_tag="VXE45_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789220.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            17506..17607
                     /locus_tag="VXE45_001189"
                     /pseudo
     CDS             17506..17607
                     /locus_tag="VXE45_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(17579..18355)
                     /locus_tag="VXE45_001190"
     CDS             complement(17579..18355)
                     /locus_tag="VXE45_001190"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0789221.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(18348..19571)
                     /gene="trpB"
                     /locus_tag="VXE45_001191"
     CDS             complement(18348..19571)
                     /gene="trpB"
                     /locus_tag="VXE45_001191"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0789222.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGCPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(19549..20148)
                     /locus_tag="VXE45_001192"
     CDS             complement(19549..20148)
                     /locus_tag="VXE45_001192"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0789223.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     YFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(20135..20902)
                     /gene="trpC"
                     /locus_tag="VXE45_001193"
     CDS             complement(20135..20902)
                     /gene="trpC"
                     /locus_tag="VXE45_001193"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0789224.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(20899..21903)
                     /gene="trpD"
                     /locus_tag="VXE45_001194"
     CDS             complement(20899..21903)
                     /gene="trpD"
                     /locus_tag="VXE45_001194"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0789225.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIITGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(21914..22480)
                     /locus_tag="VXE45_001195"
     CDS             complement(21914..22480)
                     /locus_tag="VXE45_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0789226.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQTIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(22477..23838)
                     /gene="trpE"
                     /locus_tag="VXE45_001196"
     CDS             complement(22477..23838)
                     /gene="trpE"
                     /locus_tag="VXE45_001196"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0789227.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEELEKALNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(24759..25760)
                     /locus_tag="VXE45_001197"
     CDS             complement(24759..25760)
                     /locus_tag="VXE45_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0789228.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(25868..26236)
                     /locus_tag="VXE45_001198"
     CDS             complement(25868..26236)
                     /locus_tag="VXE45_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789229.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(26332..27042)
                     /locus_tag="VXE45_001199"
     CDS             complement(26332..27042)
                     /locus_tag="VXE45_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0789230.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(27045..28736)
                     /locus_tag="VXE45_001200"
     CDS             complement(27045..28736)
                     /locus_tag="VXE45_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0789231.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(28748..29758)
                     /locus_tag="VXE45_001201"
     CDS             complement(28748..29758)
                     /locus_tag="VXE45_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789232.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(29862..30929)
                     /locus_tag="VXE45_001202"
     CDS             complement(29862..30929)
                     /locus_tag="VXE45_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0789233.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(30954..31613)
                     /locus_tag="VXE45_001203"
     CDS             complement(30954..31613)
                     /locus_tag="VXE45_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0789234.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(31777..32787)
                     /gene="galE"
                     /locus_tag="VXE45_001204"
     CDS             complement(31777..32787)
                     /gene="galE"
                     /locus_tag="VXE45_001204"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0789235.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNIFE
                     SVNKIPIPYKIVPRRSGDVATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            complement(32800..34275)
                     /gene="galT"
                     /locus_tag="VXE45_001205"
     CDS             complement(32800..34275)
                     /gene="galT"
                     /locus_tag="VXE45_001205"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0789236.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            complement(34288..>34760)
                     /locus_tag="VXE45_001206"
     CDS             complement(34288..>34760)
                     /locus_tag="VXE45_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0789237.1"
                     /translation="DKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKN
                     LQILQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELS
                     INMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
BASE COUNT        11069 a         7232 c         5334 g        11125 t
ORIGIN      
        1 atattaaagt tatataatag tattaatcaa agaaattgat tttttgatat taaaataaaa
       61 aaggagggta ggcagtgttg tgatcaatta ttgctggagg tcttattggt ctcttggcag
      121 gtaaaatcac taaaaaagta gttctatggg aatcatcgca aatgtattcg ctggtttagt
      181 cggggcatat gcaggacaat ctcttttagg tagttggggt ccatcaatcg ctggaatggc
      241 tttgctccca tctattgtag gtgcagcgat tgtgattact gtagtgtcat tctttacagg
      301 tagaaagtaa acttttcgcc agtaaagtta gcaaactatt tttaaatcaa tgacgggaaa
      361 aatagtttaa atgttaaatc gaaaggattg tatatgtcaa aagcaaagaa aatatgtttc
      421 attattttct gtattttaat cttgacaatt ttccttcctg ttttgataga ttatcatcaa
      481 gttagtgatc taggtattca tctacttagc tggagacaga actccgtagt tgaattctat
      541 cttgctagat atgtcttttg ggggacagtg gttctatcaa ctttagtttt attatccatt
      601 ttagttgtga tgttttatcc taaacgttac ttggaaatcc aacttgaaac taaaaacgat
      661 acattaaaat taaagaattc ggcaatcgaa ggttttgtta gaagtttggt gagtgatcat
      721 agattgatca agaacccaac tgttcatgta aatttacgaa aaaataaatg tttcgttcat
      781 gtagaaggta aaattcttcc ttcagacaac atcgctgaca gatgccaaat aattcaaaat
      841 gaaataacta atggattgaa gcagtttttt ggtattgagc gtcaagtaaa acttgaagtt
      901 gcagtaaaaa attaccaacc aaaacctcaa aacaaaaaga ctgttagtcg tgtgaagtaa
      961 ggaagtaaaa aatggaatgg cttaaacaat atcgatatcc aattatcgct ggtctcatag
     1021 gcgtatttct ggcttgtttg attgtctcct ttggcttctt caaaacaata tttgtattga
     1081 ttttaggagc actgggagtt gcagctggat tatatatcga aaaaaactat atagataaat
     1141 aaaaaaataa aaattactaa tttaattaaa ggagtttcat atgtcaaacg aaaaaaacac
     1201 aaacactaac gtagaaaaga aagatgctac tgttgtagct cacgaaatca aaggggaact
     1261 tacttacgaa gataaagtta tccaaaaaat cattggtctt tcactagaaa acgtttcagg
     1321 tcttttggga atcgatggtg gtttcttctc aaatcttaaa gaaaaaatcg ttaacagcga
     1381 tgacgtaaca agtggtgtta acgtagaagt tggtaaaaca caagttgcag ttgacttaaa
     1441 cgttattgtt gagtaccaaa aaaatgttcc agctttatat tcagaaatca gagaaatcgt
     1501 atcttcagaa gttgctaaaa tgactgactt ggaaattgtt gaaatcaacg taaacgttgt
     1561 cgacatcaaa actaaagaac agcatgaagc agactcagta agccttcaag atcgcgtatc
     1621 tgacgttgct gaatcaacag gagaattcac ttcagaacaa ttcgaaaaag ctaaatctgg
     1681 tcttggatct ggtttctcaa ctgttcaaga aaaagttagc gaaggtgtag aagctgttaa
     1741 aggtgcagca aatggtgtag tatctcacga aaacactcgt gtaaactaag ataaaataaa
     1801 tataacagga gaaattatca tgtcagtaga agaaaaatta aatcaagcta aaggttctat
     1861 taaagaaggt gttgggaaag ccatcggtga tgaaaaaatg gaaaaagaag gagcagctga
     1921 aaaagttgtt tctaaagtaa aagaagttgc cgaagacgct aaagacgctg tagaaggtgc
     1981 tgtagaaggt gttaaaaaca tgttgagtgg cgacgataaa taaggttaaa agttacttta
     2041 tctttttggt aacattagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     2101 tgcggaaccc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     2161 gccatgagta cgaatcccat gtcaattctc acttgacgct tccctctcag atgacatctc
     2221 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     2281 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     2341 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     2401 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     2461 acaggtgctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     2521 atgttcttgt ggcatattca ttagattttc gtaaaaagtt ctctcctatt tgtgagcgaa
     2581 caggtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     2641 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     2701 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     2761 cttttttgcg aatctaggat gtccaagaca gcggtgtctc aacgaacatt caaatagact
     2821 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     2881 ggctgggtaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaatgca
     2941 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     3001 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     3061 ttttctgagt tggtaagact gtctagctta atttgacaaa tggagggcgt taaatccagt
     3121 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaacaaatta
     3181 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     3241 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     3301 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     3361 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     3421 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     3481 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     3541 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     3601 atcatttgaa caatggatac tagccgtact gataattgag ataacaaaac ttgaaaaata
     3661 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     3721 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     3781 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     3841 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     3901 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     3961 taaaacctag atggctacta gtggaagtag aaatacatcc atttctagca gctactcggt
     4021 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     4081 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     4141 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     4201 taggtaaaaa ttcatagaca ggagccgttc ctataaatcc atctaaggca gtattttcat
     4261 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     4321 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtcg
     4381 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     4441 ctggatggtc ttctaaaccc actagattac tattctcacc gtagggatgt ttccagcaag
     4501 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
     4561 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
     4621 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
     4681 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
     4741 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
     4801 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
     4861 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
     4921 acgaacaata ggttgatatt tttcacttgg atacaaatca ttcatttcat gcggatcttt
     4981 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
     5041 tgtcaaaata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
     5101 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
     5161 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
     5221 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
     5281 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
     5341 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttagggc
     5401 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
     5461 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
     5521 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
     5581 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
     5641 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
     5701 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
     5761 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
     5821 tagatagtca ctagcataat caaattgact tccataagcc ttatcatact ttctatcaac
     5881 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
     5941 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
     6001 agtattagta aaattccaag gcacctcatc ttgataacca actcgtccac ttttatcttg
     6061 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
     6121 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
     6181 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
     6241 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
     6301 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa aacaataaca
     6361 ttcttgttat gttttataga aaaatgaact aaaatatgac taaatcgatt aggaaattca
     6421 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aataaactat
     6481 aaacctttgt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
     6541 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
     6601 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
     6661 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
     6721 gcattaccca agtaacgttt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
     6781 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
     6841 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
     6901 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacta
     6961 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
     7021 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
     7081 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattca
     7141 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
     7201 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
     7261 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
     7321 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
     7381 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
     7441 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
     7501 tatcaattcc ttgtaagatt tgatctaatt tcacatctcc tacatttgcc aaagggaaac
     7561 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
     7621 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
     7681 aggaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
     7741 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
     7801 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
     7861 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
     7921 ttttatccaa cattgtattc ataccaaact cctaattttt ttcaaatcgt tcgtatactt
     7981 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
     8041 gtaccatcaa gaggctaatt gatgtttttt ccccctgtgc ctctcttgtc aacatttctg
     8101 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
     8161 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
     8221 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
     8281 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
     8341 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
     8401 tcccctagta aatagcgaac ttgaggacct aaaagcaaca catttacttc ttttgttgct
     8461 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
     8521 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacatgct
     8581 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
     8641 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
     8701 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
     8761 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
     8821 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
     8881 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
     8941 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
     9001 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
     9061 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
     9121 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
     9181 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
     9241 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
     9301 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
     9361 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
     9421 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
     9481 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
     9541 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
     9601 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
     9661 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
     9721 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
     9781 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
     9841 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
     9901 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
     9961 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    10021 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    10081 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    10141 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    10201 tttgaatttt ttattaaatt ttcattagca aaaactttcg catgaataaa tattaataaa
    10261 aataatataa ataaacttaa aattaatttc ttattcttca ttttatcacc tatttactga
    10321 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    10381 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    10441 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    10501 agtaccaata gcactcaata caagaccacc cttactatga acgagatcaa cgacttcacg
    10561 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    10621 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    10681 cccgtgcatt ttaccagcta taatcaaacc tgagaaattc tctttagcag attgaactgc
    10741 tttgataatc tcttgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    10801 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    10861 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    10921 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    10981 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    11041 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    11101 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    11161 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    11221 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    11281 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    11341 ggtggcatag tccaacctgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    11401 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    11461 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    11521 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    11581 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    11641 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    11701 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    11761 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    11821 tttcctaaaa gtccaagtgg acctcccaaa gctacttgag caatttcatg aagattaggt
    11881 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    11941 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    12001 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    12061 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    12121 ctaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    12181 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    12241 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacccaga
    12301 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    12361 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    12421 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    12481 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttgtta
    12541 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    12601 gtaaacattt gattattttt tattatcaat atataataaa aagagaccag taagtaatga
    12661 aaagcttaaa aaaattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    12721 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    12781 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    12841 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    12901 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    12961 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    13021 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    13081 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    13141 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    13201 ataattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    13261 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    13321 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    13381 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    13441 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    13501 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    13561 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    13621 aagttatttt aactgcttat caattaggtg acactggaat aatcacactt atccatcaag
    13681 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    13741 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    13801 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    13861 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    13921 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    13981 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    14041 tatactccta tctccccttt ttcataatgt atagtaaaat gaaataataa caggacgaat
    14101 cgatcgggac agtcaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
    14161 gtttcaatct actatatttt tgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    14221 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    14281 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    14341 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    14401 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    14461 ccaaggcttg aagggtcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    14521 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    14581 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    14641 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    14701 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    14761 ttcagccagt cactgcgatt cctgtcagac tcgcttgcgt cccttagatt tgattccgat
    14821 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    14881 gtatgccctc tttgaattag tcttaggact cctctttctg ctttactctt gggaattgct
    14941 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatct acgactttca
    15001 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    15061 tggctggaat ctggtcatgg tctccttcct tgctcttgga attttggctc attttatcga
    15121 tatccgcatg ggcgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    15181 aacggagtta ctgatcttga ttcagtttgc ttctgcgacg ggtatcctgg cctttctcct
    15241 gcaaaagaaa aaggagagac ttcctttcgt gcctttcctc ttacttgctg cttgtgggat
    15301 tatttttggt aagctactgc ttgtctgata aaatccaatt tctgccatat gtccttcatg
    15361 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    15421 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    15481 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    15541 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    15601 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    15661 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    15721 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    15781 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    15841 aataatttgc ttcttgctcc aaacgattgc catcttcatt catatcttta tatttatgta
    15901 aaagaatatg tcctagctca tgagctaagt caaaatttcg acgtacagat gatttattcg
    15961 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    16021 cattaattaa tcgttccacg atatagatac ctgaacgttc taatttataa agcaaatcat
    16081 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    16141 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattata atattaggta
    16201 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    16261 gaatatctat tgttttccgt gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    16321 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    16381 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    16441 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    16501 gtaattcttt caatacccga ccattaaaca tttatatact ccttactact tttgaccttc
    16561 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    16621 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    16681 caaatcttga atcaagtgta gctgaccagt tcgtgcatca ggcataacaa catctacaga
    16741 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    16801 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    16861 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    16921 attcatctga gcgtattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    16981 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtatt
    17041 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    17101 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    17161 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    17221 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    17281 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    17341 taattatctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    17401 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcgcttt ctgaaaatat
    17461 tttaggaacc gtagtgtaat attccagatt caattcacta taaaactgac ctttctcctg
    17521 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttgatt
    17581 atttttggta agctactgct tgtctgataa aatcctgaat cggctctcct tggtggagag
    17641 cttttactat ttttgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    17701 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    17761 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtc accccattga
    17821 tggcaacggc atagacgaat ccctccgcgc cttcaatcaa ctctttctgg cgctcaattc
    17881 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    17941 caaagttggc atgttcatga ggcaagtctg ggataatcaa gcccttcaca gctgtatcag
    18001 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    18061 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    18121 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    18181 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaga aagtggattg
    18241 tttctcctag tccatccaaa cctttctcgt ggtctccagc catgatatag ggaacaaaaa
    18301 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    18361 tctcccttct ttgctgcatc tgcttccaag cggtctttga cttgaaccac atccttgtcc
    18421 ccacgacctg ataggcagac aatcatagac ttttctggtc caagttcttt ggccaatttc
    18481 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    18541 aagagttgga atccttccaa agcttcttcg tctgtcacag ggacatagct ggcacgttta
    18601 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    18661 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    18721 aggacacctg gacaaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaagt
    18781 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    18841 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    18901 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    18961 atttctggaa atggatgagg ccccaaggca gaaccaagaa tatagtgggt atcatcgata
    19021 ttagccaccc atgaacgaag ggctgcatta accgcatcct tgagcacgcg cgaaccatct
    19081 gtcacggcct cgaccttagc tcccaaaagc tccattcgga agacattgag ggcttggcgt
    19141 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    19201 gcagttgcca caccgtgctg accagcaccc gtttctgcga taattttctt tttacccatg
    19261 cgtttggcaa gccaaacttg tcctaaggca ttgttaatct tgtgggctcc tgtatggtta
    19321 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    19381 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    19441 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    19501 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    19561 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    19621 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatatt gaattgcttt
    19681 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    19741 atccagttga ccccaatcaa agggctggcc acttcctgcc acaggggcat caaagagtag
    19801 ataatctgcc tgagaattag ggacatgccc atttccatct acctgcacag cctgaatact
    19861 ggcacaaggc aaattctcaa ataaatcatc tgccacctga ccgtgaactt gaaccaagtc
    19921 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    19981 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    20041 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    20101 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    20161 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    20221 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    20281 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    20341 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    20401 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    20461 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    20521 ctgcattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    20581 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    20641 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    20701 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    20761 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    20821 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    20881 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    20941 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    21001 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    21061 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc ctccacgaat
    21121 atcttccata gcatagcctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    21181 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    21241 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    21301 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    21361 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    21421 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgatgc cagttttatc
    21481 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    21541 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    21601 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    21661 acctgtacca caattgtcca tggcatcatg aatctcagtt ggaatatgct gggcatgtcc
    21721 tctcatgact tgggcaatgg ctgtgcgttc ttcaggtgtt tcccccttca tcttaagagc
    21781 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttatgatac gctcaatgac
    21841 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    21901 catcctagtt tcctcacttt acaacctcct cgataaaatt ccgaatagaa gacaagccgt
    21961 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    22021 gaatccccat gatggtttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    22081 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    22141 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    22201 ccaaacctag cttaccacca aagacttctg caatggcttg gtggcccaaa caaatcccta
    22261 gaatcggctt cttgcctgca aaatcacgaa tcatgtcttc catctttcca gcatcaactg
    22321 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    22381 tggaatcatc atttctcaga acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    22441 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    22501 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    22561 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    22621 ggcgatggcc aaatccatat cacccgtcgc agacaagtag ccgattgccc cagcgtatac
    22681 tccccgtttt tccgtttcca gttcatagat acgtctcatc gctcgaatct ttggcgctcc
    22741 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    22801 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    22861 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    22921 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    22981 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    23041 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    23101 cccaaaatca tagaaataaa ggtaattaga aggattagtt acgcggagat ttctgtagaa
    23161 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    23221 atcaccatta cgaatcaagt cacgagctgt ttccaccatt tcctcaaact tctgaggagc
    23281 gatatgcggt ttgaagtcta acggagatag atccaagtct tcaaactcat ttggagcagg
    23341 aatgcgtaat tcctcaagca cttggttcaa ggctttttcc aattcttctt gactacgctc
    23401 actatagaga gcatcctcga tgacatgtat cttctccttc ttgtggtcaa agaccatata
    23461 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    23521 aatttcttca taaagcgaaa tcatatcgta acccacaaaa ccaatggctc caccaccaaa
    23581 agggagctct gagtggtgct gactcttatg aatcacttca taaaggaaat ccaagggatc
    23641 ccgatcaatc acttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    23701 tggattatag gctaggatag aaaaacgagc cgtttccttg tctctcggaa tactctctaa
    23761 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    23821 atgaatgatt cgttccattg taatttccct ttcagttcta attctagttc gtggcgactg
    23881 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    23941 ttataggatt tctcctatct ctcattcctg tctcagatac ctcctgtaac aggctgtgcg
    24001 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    24061 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    24121 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    24181 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    24241 atctcttcaa accgcgtcaa cgtcgcctta tcgtaggtaa cgacggatag aaaaaagccc
    24301 acacacagaa tatacttccg tgtgagggcg ttggtaacgc ggtgccacct caattataaa
    24361 gggactatcc ctttacatct ctgccttgtt taacaacaag ctgcactgta aggtgtgcgc
    24421 accgaatttt cattgtttca aattcatttt caaaatcagc ccactttcac tacttccaac
    24481 cacctattca caatcaccac aggctccctg aagatcaaaa atagttactt ttctgatttg
    24541 ttgaacttat tttaatactt tgttttttct ttgtcaagac ttttttacga tttttttgat
    24601 atcattcgaa tgtgaccata tcttccttag atcgaacatg aacatgtccc acttgttaga
    24661 aattggatcc aactcaatag aaactgaatg gaggctaaac agaacttatt ttagaacact
    24721 ccatcttttc cactaggatt ttcaagaatt aaacaatact agaaactctg tctcctaaca
    24781 aatttaggag aaacttcaac agatgtgaca ctttcccctt taataattgc taaaacacct
    24841 tctatcattt ctttagccaa tttaacataa ttgggagcaa ttgtagacaa agctggagta
    24901 taatactgag aaataggaat attatcaaat ccaatgatag aaatatcatc tggaataaga
    24961 attcctttct catagcacgc acgaatcaag ccctgaacct tttcatctcc tgaaacaaaa
    25021 ataatgtccg gataattttg ggtagtcaag tgctgcattg cataagaata aactgaatca
    25081 attgtagata agccataaat gacttttaaa tccataaagt aatttttatc attcagaaaa
    25141 gaacgcacac ctctttcacg atccttatta acatgagatt ctcctcccat aagcaaccac
    25201 atatttttaa atttttcttc agttacagct ttcatcatat cataagtagc ttgaaaatta
    25261 ttattagata catagactac tccagacgtt tgagattcac cgaaaacaag aaaaggcata
    25321 tggttcttct ttaaatactg aattctgata tcatctacac tttcataaaa aacaataaca
    25381 ccatctacta ggctacctgt gcttgatata attgaattac taattgtatc ctcctctcca
    25441 aagtactcaa ctatagcatt aacaccaaat tctttacacg tccgtaacac tttatctaac
    25501 agcgtatgaa accaaattaa aggaaaagag tcgatttttt ttacagaaat caatatattt
    25561 atagcttctt ttttagttaa attttttgca tacgcatttg gaatatacga caattcctct
    25621 ataacttttt gaatcgcttg ataagtttct tctttaacat ttactccacc attaataact
    25681 cgtgaaactg tttttggaga aaaacctgat aaacgtgcaa tatcataaat agttaccttt
    25741 ttcccattta tatttttcat ttcagtcctc cattacgaac attctaatat tactatacaa
    25801 tatttaattt tttttaacaa gagaatttag taaattattt aagatccaca aattcacaaa
    25861 attaatttta caaatattct tccccttcaa aaaagtttaa attgcatttc acacctttat
    25921 ttttaagaat gtttccaact tcacgacaaa taaattcata tgagaaaaaa ctgccataaa
    25981 attgtagatt aactttttca gtaaaatgtg taggatttat aaaaacatat aatagcctgt
    26041 caatgtaaca ttttaacata gagttaattt tttctttaaa gataacattt gttatcaact
    26101 catcaggagg taaatgaaag gcaaacacca tttcacaaat atcataaaaa gaaataaatt
    26161 tgtatacttg tatcaaacaa ttattatcaa aatattctat tttacctaaa tcaaaattga
    26221 ttttataatc tttcataaaa acctctgagc aaaaatctac tcaaaaatta gatgattaaa
    26281 acatctaaaa aacaaaagga caaaaacatc tgtccctttg tttactaaat ttcagctaat
    26341 ttcttcgaca taaataacac ctacaatatt agcaatttct tccatcagtc gaagatgttc
    26401 aaatctacct gataattcca gagtaataaa tgacgctatt tttttgtccg gaacatcaaa
    26461 gtattcaatt ctgtcagaat taacatctcc aaacgctgtt cttgaatcgg tcattctgat
    26521 accattttct gcacaataaa ccaatacacg attataggct tctgtagatt taactactat
    26581 atacaattca atcattttag aacgattttg cagatatttt tttagtggtt ggaacatgga
    26641 tatcacaccc caaacagaaa tggctactaa aagagctccc tcataaaaac ctactccaat
    26701 agctaatcca attcctgccg aagcccaaat gcctgctgca gttgtcagac ctgtaatttt
    26761 cttcttatct gtaataagaa tcgttccagc gcctagaaaa cccacacctg atataacttg
    26821 agctcctaat cgtgtaggat ctcctgtccc aaatttataa gatacgtatt cattcgtcat
    26881 cataatcaaa catgcagcta gacaaacaat actataagtt cggatgcctg caggctggga
    26941 tttgctccct ctctctaaac caattatact accaatgact actgataaaa caatcctgac
    27001 aactatttca atatttgata acccaagact agtggctgtc atgattattt ccttacttta
    27061 cgccccggtc tttgtgtgaa gtataatacc gttccagaaa taatcatcag aacaattgta
    27121 taaacaaata ccagagcttg tgcattagat gttgctgttt catcacctgc agatcgaatc
    27181 gtaataccta atggttgagc taggggatgg taaaggaata cagataagtc gaagtcagtt
    27241 aataaagagt taaagtttaa agcaataaca gagagaacaa ccggtaaaat aaatggaatg
    27301 ataaccttca tcatagtata aaaaggtgaa gcacccatac ttcttgctgc atcttccatc
    27361 tcatcatcaa cactaaataa aatagcacgt accattctat aagaaaatgg gatttttaca
    27421 actatatatg caataagtag aattaccaaa ctacctacca aaatctgatt caaaacaaga
    27481 aattgtggct gattaaaagt aaataataaa cttactgcta aaagtgtact tggtagtaac
    27541 caaggaagta gagcaccata ttcaaataag aaatcaaaac gagatttatg ttttctgaca
    27601 acacgagcaa atacaactgc gagaattgtt gctgttgtcg cagcaataat agaataaata
    27661 aagctgacca agaatggaga gaatgccgca ctattactaa agaataagcg ataattttct
    27721 aaagtaaagt ttgataatgt taagttacct gtttgaattg caactggatc tgtaaatgag
    27781 tataatacta taaaaattag tggaagcatg aaaactgtga acaatccata tgctacaatg
    27841 tgagcaatga tattccaagg cttagacgca attttttgtt ttttaagagg cgctttagtc
    27901 ttagagatag aaatataatt tccacctttt tctatcttat tcatgatagt aagcaaaatt
    27961 gtagttgcaa tacctaaaat aattgcaagt aaggcagcta aatcacgaga attccccatc
    28021 cctgcaaatg taataatcat tggatttata gtttgaaatt ctttaccacc aacaatcatg
    28081 ggtgctgcta ctgcagataa accactaaga aaaaccataa tagtaagtgc aaatagagtt
    28141 ggaattaagg ttggtaacac tacttttcgg aaaacagtaa atggttttgc tcccatattt
    28201 cgagcagcct caatagtgtg atagtcaacg cttcgaattg tatttgttaa aaacaatgta
    28261 tgattagcag ttcctgaaaa tgtcataatg aataagactg caccataccc aataaaccag
    28321 ttagagtcta aagaagggat aacattttgt aaaaattttg taatcaatcc ataaggacca
    28381 tagacaaatt tatatccagt cgctaaaacc actcctccat aaattaaaga ggtcatataa
    28441 cctaatttta aaattttagc acctttaata tcaaagtact ctgtaaatag aacacaaaga
    28501 atacctacga cattaactgt aataatgagt gaaaatgcta acttaaaact gttcataata
    28561 ctctgaagtg ccctctgaga ttttagaaca cgatgtacag catcaaggga aaattctcct
    28621 ccttttacaa atacattcac tactagatca aagtttggat aaataataaa tgttactaag
    28681 aaccagatta accctaaacg aataagccaa tcttttaaat ttaatttatg acgcatactg
    28741 cacctcctta aaattgcaga acgtctgatg gtgtgataaa taattccaca ctttctccga
    28801 cagatctaat agcagcctga ctatcaatac ttgttacatt aagaatctga ctttcagaaa
    28861 cttttattgt atagtgaatt gtaactccag aaaactcaac atcaataatt gtccctttta
    28921 gaataaaatc ttgttcagtt tcacgattga atcgaacttt ctctaatcga atgtatcctt
    28981 ttttatcctc taagaaaacg cttgtatttt tcaataatac ttcgtggact gtttcatcgg
    29041 tcaaaacatt aatatctcca ataaaatcac atacaaattc agtttgagaa ttatgataaa
    29101 tctctactgg tgtaccgacc tgttcgatgt atccattgtt aaagactgca attctatcag
    29161 ataaagtcaa ggcttcctct tgatcatgag taacatataa agtagtaata cctaactctt
    29221 tttgaagtct tttcaactct tttctcaaat ctacacgtaa ttttgcgtca aggtttgaca
    29281 atggttcatc tagacaaaga attttaggtt caagaaccag agcacgagcc aatgctaccc
    29341 tttgttgttg acccccagat aattctgata cattacgctg taactgttga tcagagatct
    29401 taatttttgc tgccactgct gatactttag ctttaataac atctggagct accttcttaa
    29461 cttttaaacc aaatgcaata ttatcaaaaa cagtcatagt tggaaatagc gcataagatt
    29521 gaaatacaat accaatccca cgcttttcag gttccaaatg agtgacatct gttccattaa
    29581 cttcaatact tcctgatgat ggatctaaaa aacctaccaa tgctctcaaa gtagttgatt
    29641 taccacatcc tgaaggccca agaaatgtaa agaattcccc ttcatgtata tctaaattca
    29701 gattatcaat tgcaacaaaa tcaccatatt taatttgaat attatcaaat ttaatcatct
    29761 cactaactcc ctctattact aaaaccaaaa gcctctcttt atttcttcct taaatttaga
    29821 aataatagag agacttggac ataaaaaata actcttattt cttattttac gtattctaat
    29881 tcagcttttt ctacccattc atccaaatgc tttccaacag cttcccagtc aatattttgt
    29941 ggtttcactt gatcaacaaa ttttttcgta tcttcaggta actcttttag ggcatcttta
    30001 tttgcaggaa tagatccaaa ttttttacta tattctactt gaatttctga ttgaccaaac
    30061 caatcaataa attctttagc taacgcttgt tttttactag tgcttaaaac catagtttgt
    30121 tcagttacaa atggtacacc aatctcagga gtcataactt tgaattcaac attttgttct
    30181 ttttgtccga ttaacgctcc agaaccccag atcataccgt attgaattgg gctttcttta
    30241 tctaacgctt taacaactga gctttcacct ttttgaagag tataggcatt tgcaaagtat
    30301 tcttttgcaa cttcccatcc tttttctgat acgcctaaat ctcctttttc atccaggtaa
    30361 cgaactaaga tacttgctag aattgcccgt cctgtaccac cttgaagacc ataaattgaa
    30421 tatttacctt tatacttact acctaattca gtccaatctt taggcatttc ttttacatca
    30481 ggcgccccaa ttaaaactaa tggttgaaca atcacaggat tataataatt atctttatct
    30541 gataaagatt gatcaatttt atctaaccat ttaggcttgt actgtactag taatttttga
    30601 tctctaattt tatttgagtc aacagcacca attccaaata ccatatctgc aactgcatta
    30661 ttcttctcag caataacacg gtctgctaat tgagcgccag cgatatcaac catttttata
    30721 ttaaaaccag cttcttttgc tttagcagtt aaccaatcac cacgaccatt tgagactgag
    30781 ttcgaataga taactaattc ttgactttta tcagcttttt cttcagatga agaagcagtc
    30841 gtagaatttg aacctccaga gcaagcagca agtgtagtaa gagcaactcc cgttgcaagt
    30901 acagtagacc aaactttcat ttttttcatg ataagttctc cttttttatt attttattta
    30961 aatttttcgt gatatggaac aaattgtctc atatcttcaa atacagtata gtcaatacgg
    31021 tttacagtaa tagttggaat cttctctaat aaaatttcag ttaattctgc tctgacttta
    31081 gtaaactctt cttcctcctc ttcggttaga ggaatccgaa gatacccaat tgaaatatgg
    31141 aattgatatc tatcatgatt agggaaacaa acacctgctt tttctgagac ataagtacga
    31201 atttcttcta atctctttgc agaagcttca tctgcaggtt caactagtat gttttgtttt
    31261 cccatttcag ttatacgcat atgaatttct tcatccaaca atggaaaaat ttcaagttgt
    31321 ttagcaaagt aatcatgtat ttcctgtaaa ggtgtatcta gaggaagatt actgctccaa
    31381 aactccgttt cacgattttc atggcacaac aattcaatta cagtcatgtg aatagaattc
    31441 cttggagtta aagtaaactt atcgataaat ggtaattctc tataacgtga ttgaataata
    31501 tcaacaactt ccatcaaatc ttgtttagta taaagatttg ctacaactgt attcccaggg
    31561 aaatgattaa attccccatt ttctttgaac ttaatttttg ttaagttttt catataaaga
    31621 ccttcttttt tatatttgac atcggtgtca ttgtgtttac attatacaat gaaaccgttt
    31681 cctttgtcaa gcgctgtcaa acattttttt taatttatct ttcattaaaa ggttaagtaa
    31741 tttttccaaa atacagcact catatagaca gtatcatcaa ttatagccat tgggattttt
    31801 tgattgccaa ttccatgtat ctctacacat gtcttcaatc gattttgttg tcctccaatt
    31861 taattcctta tatgctttgt ctgcatttgc ataataagtt gcaacgtctc ctgaacgtct
    31921 tggaactatt ttataaggaa tagggatctt attaacactt tcaaatatat ttacaagttg
    31981 taatacacta gtgccttctc ccgagcctag gttatagata taaacatctg ttttttcaga
    32041 tactttttct aaagctttta tatgtcctat tgctaaatct actacatgga tataatcacg
    32101 cacaccagta ccatcaagcg tatcataatc atttccgaac acacttagct ctgatagctt
    32161 acctaccgct acttgtgcaa tataaggcat caagttgtta ggaattcctg agggatcttc
    32221 cccaatcaaa ccagactcat gagcaccaat tggattgaaa taacgaagca acgcaatact
    32281 ccattctgaa tctgccacat gaacatcttt taaaatttgc tcaagcatca ctttcgtata
    32341 cccataagga tttgtcgcac ttgtttgcat cgtctcaatt agaggtgact gattgttaat
    32401 tccatataca gtcgcacttg aagaaaagac aatcttttta acattaaatt ctgacatcac
    32461 ttcaacaagt gccaatgtac tcataatatt atttttgtag tacatcacag gcttttgcac
    32521 ggattctccg acagctttat aacctgcaaa atgaattgca gcatcaatcg attcttgttc
    32581 aaataccttt ctcaatgctt gtttatcaca aacatctaat tcgtaaaaca cgggacgtat
    32641 tcctgtaatt gcttcaatac ggtctagcac caatttgcta gagttcgaaa ggttgtcgac
    32701 aatgataact tcctttccta aatttagtaa ttctactacg gtatggctac caatataacc
    32761 agctccgcct gttaccaata ttgccatctg ggtttcctcc taattaattc caaccgactt
    32821 aacaaatctc ataaacgctt catgcccaga cggtgtattc ttataaactc ctgcatcttc
    32881 cagaactctc gcaaacactt gtcctgcttc gtgttgaact acgctattaa cctcttcttt
    32941 attaatgcga ggatattttt ctttcaattg gtcggcccat tctaaatgat aatccgcaat
    33001 tgcattatcc tctcctaaaa gatattttcc aacttcttct aactctggtt tcaaacgagg
    33061 tggtaatatc gcaagtccca tcacttcgat taacccgata ttttcctttt taatatgttg
    33121 tacatcttga tgaggatgga aaacaccatc tgggtattgt tcagtagtat gattatctct
    33181 tagaacaata tctaattcgt atctcccgtc cactttacga gcaataggag tcaccgtatg
    33241 gtgtgggaca tcttcagtca tagcaatgat gtctacttct aaatctgaat attctctcca
    33301 cttatttaga attttagtag ctaaatctaa caagcgattt ttattttcac tttgtaacct
    33361 aattactgac attggccatt ttacaatacc agcattaaca tcctcaaagt ctttaaaaca
    33421 aaattcactc tcaaattttg ctttttccat tgggaaaata tgtttccctc cctggtagtg
    33481 gttatgacta agaatggagc ctcctgagat aggaagatca gaatttgaac cagcaaaata
    33541 tcctggcaaa atatcaacaa tctccaataa ttgttcaaat gttttagagg taatagccat
    33601 tggtacatgt tgactattca aaaatatcgc atgctcatta aagtatgagt agggagaata
    33661 ctggaatccc catacttcgt caccaagttt caaccgaata attctatgat tcgaacgtgc
    33721 tggataattt attcgcccct gatatccttc attttccata catagtaaac atttgggata
    33781 attagttgct tttactaatt tttcagcagc aattgttttt ggatcttttt cgggttttga
    33841 caaatttatc gtaatctcta gctctccgta tttagttgat gctcgaaact caatattctt
    33901 agcaatagca gaagttttaa tataatcact atctttactt aacttataaa actcttcaac
    33961 tgcttcttga ggtgatatat catatgaact ccaaaaaata tcatttaatc gactaggtaa
    34021 aggaactatg aaattcatta actctgctcc taaacattcc ttttcctcga ttaaatcttt
    34081 aattttaccg ttttttaagg cgatttccac taagtaatct tttatttgtt tcaggtcatt
    34141 ttcatcggaa atgcgatcaa ttccctcctc acctattaac gctagtactc tatttttcac
    34201 atatattttg tcaatttcat tatacattcc gtattcaatt actctatcaa caaaattatc
    34261 aataattgtt ttcatatatt tttctttcta atttatgttc ccatattttc tatacattat
    34321 ccatttataa attgcttgcg tagtatgagc aattttatca aggtgatgaa taatatctaa
    34381 agcactaatt acttcagaaa cgttcccatc atcttcaaat atgtaattca ttattttctt
    34441 ttccatattt atactaagct cttctatctc attctgtttt tgtataacaa ccatatctaa
    34501 acatccagat tgttcctctc tataacaaga tatagcccta ttcatatgca gtccgataac
    34561 ttcatgaagt atttttattt ctgaaataat tttcttcaaa atttcattat tttgaagaat
    34621 ctgtagattt tttaaaattt caacaattct atccccaata cgttcaatgt cagttgatat
    34681 ttttattaca ctaataattc ttcttaagtc atatgaaaca ggatgttgta aacaaattaa
    34741 ctcatatcct tttttatcaa
//
LOCUS       DAVLHM010000024        34210 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLHM010000024 DAVLHM010000000
VERSION     DAVLHM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.024"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..243)
                     /locus_tag="VXE45_001207"
     CDS             complement(<1..243)
                     /locus_tag="VXE45_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0789238.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFK"
     gene            complement(425..661)
                     /locus_tag="VXE45_001208"
     CDS             complement(425..661)
                     /locus_tag="VXE45_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0789239.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(674..1147)
                     /locus_tag="VXE45_001209"
     CDS             complement(674..1147)
                     /locus_tag="VXE45_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789240.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(1165..1350)
                     /gene="briC"
                     /locus_tag="VXE45_001210"
     CDS             complement(1165..1350)
                     /gene="briC"
                     /locus_tag="VXE45_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0789241.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1509..2276)
                     /locus_tag="VXE45_001211"
     CDS             complement(1509..2276)
                     /locus_tag="VXE45_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0789242.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(2273..3139)
                     /locus_tag="VXE45_001212"
     CDS             complement(2273..3139)
                     /locus_tag="VXE45_001212"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0789243.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(3176..4543)
                     /gene="accC"
                     /locus_tag="VXE45_001213"
     CDS             complement(3176..4543)
                     /gene="accC"
                     /locus_tag="VXE45_001213"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0789244.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4555..4977)
                     /gene="fabZ"
                     /locus_tag="VXE45_001214"
     CDS             complement(4555..4977)
                     /gene="fabZ"
                     /locus_tag="VXE45_001214"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0789245.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4974..5459)
                     /locus_tag="VXE45_001215"
     CDS             complement(4974..5459)
                     /locus_tag="VXE45_001215"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0789246.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5462..6697)
                     /gene="fabF"
                     /locus_tag="VXE45_001216"
     CDS             complement(5462..6697)
                     /gene="fabF"
                     /locus_tag="VXE45_001216"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0789247.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6719..7450)
                     /gene="fabG"
                     /locus_tag="VXE45_001217"
     CDS             complement(6719..7450)
                     /gene="fabG"
                     /locus_tag="VXE45_001217"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0789248.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(7484..8404)
                     /gene="fabD"
                     /locus_tag="VXE45_001218"
     CDS             complement(7484..8404)
                     /gene="fabD"
                     /locus_tag="VXE45_001218"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0789249.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(8397..9371)
                     /gene="fabK"
                     /locus_tag="VXE45_001219"
     CDS             complement(8397..9371)
                     /gene="fabK"
                     /locus_tag="VXE45_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0789250.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(9490..9714)
                     /locus_tag="VXE45_001220"
     CDS             complement(9490..9714)
                     /locus_tag="VXE45_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0789251.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9774..10748)
                     /locus_tag="VXE45_001221"
     CDS             complement(9774..10748)
                     /locus_tag="VXE45_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0789252.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10748..11182)
                     /locus_tag="VXE45_001222"
     CDS             complement(10748..11182)
                     /locus_tag="VXE45_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0789253.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(11276..12061)
                     /locus_tag="VXE45_001223"
     CDS             complement(11276..12061)
                     /locus_tag="VXE45_001223"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0789254.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12430..13794
                     /locus_tag="VXE45_001224"
     CDS             12430..13794
                     /locus_tag="VXE45_001224"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0789255.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13797..14168
                     /locus_tag="VXE45_001225"
     CDS             13797..14168
                     /locus_tag="VXE45_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0789256.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14382..15656
                     /gene="serS"
                     /locus_tag="VXE45_001226"
     CDS             14382..15656
                     /gene="serS"
                     /locus_tag="VXE45_001226"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0789257.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(15681..16580)
                     /locus_tag="VXE45_001227"
     CDS             complement(15681..16580)
                     /locus_tag="VXE45_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0789258.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16690..17238)
                     /locus_tag="VXE45_001228"
     CDS             complement(16690..17238)
                     /locus_tag="VXE45_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0789259.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17456..18778)
                     /locus_tag="VXE45_001229"
     CDS             complement(17456..18778)
                     /locus_tag="VXE45_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0789260.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18869..18957)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(19121..21457)
                     /locus_tag="VXE45_001230"
     CDS             complement(19121..21457)
                     /locus_tag="VXE45_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0789261.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRKVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21561..22109)
                     /locus_tag="VXE45_001231"
     CDS             complement(21561..22109)
                     /locus_tag="VXE45_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0789262.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQIYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(22106..22408)
                     /gene="zapA"
                     /locus_tag="VXE45_001232"
     CDS             complement(22106..22408)
                     /gene="zapA"
                     /locus_tag="VXE45_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0789263.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22495..23379
                     /locus_tag="VXE45_001233"
     CDS             22495..23379
                     /locus_tag="VXE45_001233"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0789264.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISLEE
                     KAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQG
                     LNFCAKLHFKNTEKAKNA"
     gene            23391..24005
                     /gene="lepB"
                     /locus_tag="VXE45_001234"
     CDS             23391..24005
                     /gene="lepB"
                     /locus_tag="VXE45_001234"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0789265.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            24133..26499
                     /locus_tag="VXE45_001235"
     CDS             24133..26499
                     /locus_tag="VXE45_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0789266.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26547..27830)
                     /locus_tag="VXE45_001236"
     CDS             complement(26547..27830)
                     /locus_tag="VXE45_001236"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0789267.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28674..29810)
                     /locus_tag="VXE45_001237"
     CDS             complement(28674..29810)
                     /locus_tag="VXE45_001237"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0789268.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGRSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29872..30309)
                     /locus_tag="VXE45_001238"
     CDS             complement(29872..30309)
                     /locus_tag="VXE45_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0789269.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(30311..32266)
                     /locus_tag="VXE45_001239"
     CDS             complement(30311..32266)
                     /locus_tag="VXE45_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0789270.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(32290..34059)
                     /locus_tag="VXE45_001240"
     CDS             complement(32290..34059)
                     /locus_tag="VXE45_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0789271.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10138 a         7682 c         6458 g         9932 t
ORIGIN      
        1 cttaaagcga cgctttctaa ggaggattct agtaggcata ccagtcgttt caagataagg
       61 aatcttagac ggtttttgaa agtcatattt cttcatttga cttccgcact cagggcaaga
      121 tggggcgtcg tagtccagtt tggcgatgat ttctttgtgt gtatccttat tgatgatatc
      181 tagaatcttg atgtttgggt ctttaatgtc tagtaatttt gtgataaaat gtaattgttc
      241 catatgaatc tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt
      301 ttttctacac aaaaataggc tccataatat ctatagggga tttacccact acaaatatta
      361 tagagccaac aataaaaaga aaaagtgttt gatagatatc aaacactttt ttctttgcct
      421 cccactatct aaaaaaatga taatagatat aattgtaaac aaaaatccag ataggttttg
      481 catgattgag aaagttaaaa aaactatggc agagaatcgt taatctcaga ttgtcggtag
      541 aacgataaac aagggcaaaa aagaaaccaa tcagactata atataataaa ctaattggat
      601 ctctgtgaga tagtatcaaa tggctaatcc caaagatgat agcagatagg ataacatcca
      661 aatagtactt ggactaggga aagaaggtat tcataaaata ccctctatca agagtctcct
      721 caaaaacagg accgatgatt acaggcagga caaaagataa gatagtcgat aaaaaggttg
      781 gttgtccatt tgaaaaaagc acggtaaaat actcatcatg aatattccta tgattaatca
      841 aatgagcata gcgtgcccaa aaattaccga gaatctgata aaccacataa gttgcaaata
      901 agtagaagac aaatgaccag ttccagctct ttttctcaaa gataaagagc atctttttct
      961 tttttaacct ccaaattaat agaaggaaac ttcccactaa tcccattgtt aaaataagag
     1021 aatagacatc agctcctaac cctaaaatga tcgtcacata caatccaatt gtttgtggta
     1081 aataggtaga tagtaaaata ataagcaaaa atattccaaa ttgtcttagt ttttttgtgt
     1141 ttctcatcgt acttttttga aagattaccc tgctcggaag ccgtacttcc aagcatctat
     1201 ataagaatta agtgcccctt gcctcatata gggagcaaat tctctataat ataaccatct
     1261 actatatcca tcttcccaaa cagcaagacc acctgaagtt tgctccaagt cctcagttga
     1321 aagaactgta aatgtatttg tacctgtcat tgcaagtacc ttcttaaaat agattgttgt
     1381 aggctcacat ttatagtata tttctttttt tgtctatttt atagcccatc tcctcaactg
     1441 gcaatttttc gacctgaatt acatttttcc ataaaaaatg agacctttct agtctcattt
     1501 agtcattctt agtattttct aaatcgttga tagcgttctt ccagcaactc ttctagcggt
     1561 ttttgtgaaa gtctagccag ctccgtttgg agttcttttt tgacactctt aatcagttct
     1621 ttactagaaa gtcctatttc agaaatcacc ttatccacca cgtccatttc taacagttca
     1681 tgcgaagtga ttttcatcag ttctgctgct tccatggcgc gagtaccgtc cttccataaa
     1741 atggaagcaa agccttctgg actgagaatg gcatagatag aattttccag catccagaca
     1801 cggtccgcga cagctagagc cagagccccg cctgaaccac cttcaccgat aataatggcg
     1861 ataataggaa ctttcaggtc actcatttcc atgagattgc gagcgatagc ttccccttga
     1921 ccacgttctt ccgctccgac accaggataa gcacctgctg tattgataaa ggtcacaact
     1981 ggacggccaa atttctcagc atgtttcatc aaccgcagtg cctttcggta gccttctgga
     2041 tgtggttggc caaaattccg tttgaggttg tcttgcaaac tcttgccttt ttggatacca
     2101 accactgtta cagcttgatc tccaagccaa ccaataccac caacaactgc accatcatca
     2161 cgaaaagaac ggtcaccatg taattggata aattcatcaa aaatgcctgt cgcaaagtcc
     2221 aaggttgtca agcgactctg ctcacgcgct tctctgacta tttttgcaat attcatctag
     2281 gactccctcc atgcaatctg actaggctag caatcgtatc tggtaagtct cttcttttga
     2341 caatagcatc cacaaagcca tgttctaata ggaattctgc cttttggaaa tcctcaggca
     2401 agctttcacg aaccgtattt tcaatcacac gacgcccagc aaaaccaacc aagctctgtg
     2461 gttcagccag aatgatatcg ccttccatag cgaaagaagc tgtcacacca ccagtcgttg
     2521 gatctgtcaa aatggtcagg taaaagagac cagcatttga atgacgttta accgccgcag
     2581 agatcttagc catctgcatg agactcatga ttccttcctg catacgggct ccaccagagg
     2641 ctgtgaatag gacaactggc aatttttcga cagtcgcata ctcaaacaaa cgagtgattt
     2701 tttcacctac aaccgtaccc atagaagcca tgataaagtt agaatccata atcccgagag
     2761 ccacagtctg acctttaata agagcagttc ctgtcacaac ggcttcatgc agacctgttt
     2821 tttcacgcat agatgccagt ttcttttggt aaccagggaa atgcaaggga tccttgcttt
     2881 caatccctgt aaacaattct ttgaaggttc ccatatcaat cgtcaaagcc aagcgttctt
     2941 gggcagaaat acgaaaggta tagctacagt gcggacagat acgttcactt cccagatcct
     3001 tctgatagat ggtatgctta cagcctggac actgggaaaa taattcatct ggaacctctg
     3061 gcttagcttg aggtttttcc ctaaccgaac gattgggatt gattcgaata tacttatctt
     3121 ttttactaaa tagagccatt gattcccctt ttcggtttaa actcttaaag tcattttatt
     3181 ctttttcttg atatttaggt aagaaggttt ccatcaagaa ggaagtatca taatccccag
     3241 caatgacatt gcgatctgaa atgaggtcaa gctggaaatc tgcattggtc tgcactcctt
     3301 caatctctaa ttcatagagg gcacgttgca ttttcatcaa ggcgtcaaaa cgattttcgc
     3361 cgtgtactat gattttggca atcatactat cataataagg cggaatggta taacctggat
     3421 aaactgctga atccacgcgc aagccaactc caccacttgg cagatagaga ttagtaatct
     3481 tacctggact tggagcaaag ttaaaggctg ggttttctgc attgatacga cactcgatgg
     3541 catgaccgcg taggacaata tcttcttgct taacagacaa aggctgacct gccgcaatgc
     3601 aaatctgttc cttaacgata tcaacacctg aaacaaactc tgttactgga tgttctacct
     3661 gaacacgagt attcatctcc atgaaataga aattgctact tgcttcatca agaagaaatt
     3721 caatggttcc tgcattctca tagccaacaa actctgccgc tcgaacagca gcagcaccta
     3781 tttcatgacg cagcgttttt ccgattgcaa tcgagggact ttcttccaaa accttttggt
     3841 tattcctttg aagagaacaa tcccgctcac ccaagtgaat cacatgtcca tgctcatcac
     3901 ctaggatttg aacctcaatg tgccgagctg gatagataac ccgttctatg tacatggcac
     3961 cattgccata attggccttg gcctcactag aggcagtttc aaaggcagaa acgaggtcat
     4021 ctggtttttc aaccttacga atccctttac cacctccacc tgctgaagcc ttgagcataa
     4081 caggatagcc aattttttca gcaacaatca aagcttcttc agagttatgc acttctccat
     4141 ctgaacctgg tataacaggc acacctgctt taatcatctg agcacgcgca ttgatcttat
     4201 cccccatcat atccataaca tgaccagatg gaccgataaa cttgatacct acttcttcac
     4261 acatggtcgc aaatttggaa ttttcactga gaaatccaaa accagggtga atagcttctg
     4321 cctcagtcaa gactgcagct gatagaactg cattaatatt gagataagac tctgttgcct
     4381 tgccaggacc aatacaaact gcttcatctg ccaaaagcgt atgaagagct tccttatcag
     4441 cagttgaata aaccgctacc gtcgcaatcc ccaattcacg tgccgcacgg ataatacgaa
     4501 ccgcaatttc accacgattg gcaattaaaa tttttcgaaa catggagaac ctccttagtt
     4561 cccaattgca aaagtaagga taccactggc tgcaagcttg ccatccactt cagcctttgc
     4621 ttcaaccaca gctatggtgc cacgacgttt tacaaaagtc gctgtcataa ccaattggtc
     4681 gcctggtaca acttgcttct tgaacttaac cttgtccata ccagcgtaaa agaccagttt
     4741 tcctttattt tcaggttttg ataactccaa cacaccagca gtttgcgcca aggcttccat
     4801 aatcagaaca cctggcataa ctgggtattg aggaaagtgg ccgttaaaga aaggttcgtt
     4861 aatggtcaca tttttgatag caacaatggt atcctcgctc acttccaaga cacggtccac
     4921 tagaagcata ggataacggt ggggaagagc ttctttgatt tcttgaatat cgatcatttg
     4981 atacgtacca atcctttacc aaactcaacc atttcttcgt tagagacgag aatttccgtt
     5041 accacaccat ccttaggagc tgggatttca ttcatgactt tcatggcttc gataattacc
     5101 aatgtttgac cttttttgac actatcacca actgtaacga aggcaggttt atctggtcca
     5161 gcagccaagt aaaccactcc aacaagtgga ctctctacaa gatttccctc agtagccaca
     5221 cttgcttcag ctggagctgg aacttcttct gctacagtct ctgctggagc agatgtagga
     5281 gctactggac tcggtgttgc tagaacgggt gctggagcga cttgagttgc aacttcaggc
     5341 acaggtctcg cttcattctt gctaaactgc aactcatccg tcccattttt ataagaaaat
     5401 tctctcaaac ttgactggtc aaattgagtc atcaagtctt taatatcgtt taaattcata
     5461 cttatctatt ctcccaacgt ttgaaagcaa gaactgcatt gtggcctcca aaaccaaaag
     5521 tatttgaaat agcgtatgga atttctttct ccaagccttg tccataaacg acattagctt
     5581 cgatataatc tgatacttca cttgtcccag ctgtcattgg tacaaagtta tggcgcatag
     5641 cttcgatggt gacgatagct tctactgcac ccgcagcccc cagcaaatgt cctgtaaaag
     5701 acttggttga tgatacaggt acttccttac caagaacagc tacgatagct ccactttctc
     5761 ctttttcatt ggcaggagtt gacgttccgt gagcattgac ataggctact tgctctggag
     5821 aaatctcagc ttcttccaag gctagtttga tggccttgat agctccctga ccttctggat
     5881 gtggagaagt catgtggtag gcatcacaag tatttccgta accaaccact tcagccagga
     5941 tagtagctcc acgtttttca gcgtgttcaa gactttctaa aaccaacatc cctgaacctt
     6001 cacccataac aaacccattg cgatccttat caaatgggat cgaagcacga gttggatcct
     6061 ctgtagtaga gagagctgtt aaggcttgga aaccagcgat ggcaaaaggt gtgatagaag
     6121 cttctgttcc tcccaccaac atcacatctt ggaaaccaaa cttaatggag cggaaggcat
     6181 ccccaatcgc atcatttgat gaagagcagg cagtattgat agatttacaa acaccgtttg
     6241 caccaaaacg catggctaca ttcccagaag ccatatttgg taaagctttt ggaagagtca
     6301 ttggtttgac acgtttgggt cctttttcat gaaggcgaag tacctgatct tcaatttcct
     6361 tgattccacc aataccagat gcaacgataa caccaaaacg atccctatta agagcctcta
     6421 catcaagatt ggcatgattt acagcctctt gggctgcata caaggcatat aaagaatagt
     6481 tatcaaaacg gttggtatct ttttttacaa agtatttatc gaacggaaaa tcttggattt
     6541 ctgccgcatt atgcacatca aagtcactat gatcaaattt tgtaatgcca ccaatgccga
     6601 ttttcccagt tgctaaacta ttccaaaatt cttctggtgt atttccgatt ggagatgtta
     6661 ctccataacc tgttaccact actcgattta gtttcattct tttcacctct agctttcgct
     6721 acatacttaa gccaccatca atggcaatca cttgaccagt tagataatct tggcctgcta
     6781 aaaatactgt caaatctgca acctgctctg cctgcccaaa ttctttcatc ggaatctgag
     6841 ctagtgtagc ttccttaatc ttatctgata agatagctgt catatcagac tcaatcattc
     6901 ctggagcaat cacattgact cgtatattcc gactagcgac ctcgcgtgcc acagacttgg
     6961 taaagccaat caagccagcc ttagaagcag catagttagc ttgaccaata ttccccatca
     7021 aaccaacaac actagacata ttaatgatag caccttctct ggctttcatc atcggtttca
     7081 agactgattg tgtcatatta aaggcaccag tcagattgac cttgagcact ttttcaaaat
     7141 ctgcttctgt catcttgagc ataagagtat cttgggtaat ccctgcattg ttgaccaaaa
     7201 catctactga acccagttct gcaatagctt gatcaatcat acgcttagcg tctgcaaaat
     7261 ctgatacatc tcctgaaatg ggaaccacct tgataccata gtttgaaaac tcagcgagca
     7321 attcttctga gattgcccca cgactgttta agacaatgtt ggctcctgct tgagcaaact
     7381 tgtgggcgat ggcaagacca attccacgac tcgaacctgt aataaagata tttttatgtt
     7441 ctagtttcat ttttttcctt tcaaaacttc tacttatttt agtctatttt tctaaaagtg
     7501 ctactaaact cgcttgatct tccacatgag ctaagtgagc agtttgatca atttttttaa
     7561 caaaacctga caagactttc cccggtccaa tctcgataaa gttgcttatg cctgcttctt
     7621 gcatgacccc aatactttca tagaaacgaa cgggttcctt gacctgacgc gtcaagagct
     7681 gagcaatgtc ctctttttgc atcacagcag cttctgtatt gccgactagg ggacaagtaa
     7741 aatctgaaaa acttacctga gctagagttt cagctagttt ctggctagct ggctcaagga
     7801 gagcggtgtg aaagggacct gacaccttaa gaggaatcaa gcgtttggca cctgcttctt
     7861 gcaaaagttc aaccgctcga tcaactgcaa ccacttctcc agcaatgacg atttgtgcag
     7921 gtgtgttata gttggctgga gtaaccactc caagttcaga agctttttga caggcttctt
     7981 caatgacctc tactggcgta ttgagaactg ctaccatctt gccagagtca gcaggagccg
     8041 cttcttccat ataggctcca cgcttagcta ccaaggcaac cgcatcttca aaatccaagg
     8101 cgccgcttgc caccaaggca gagtattctc caagagacaa accagcaacc atatcaggct
     8161 gatagccctt ttcttgcaat aaacggtaga tagcaaccga agtcgctaga atggctggtt
     8221 gcgtatagcg ggtctgattg agtttgtctt cttccgtatc gatgagataa cgcaaatcat
     8281 aacctagcac ctgactcgct cgatcaatcg tttctttaac aatcggatac tgatcataga
     8341 aatcccgtcc catccctaga tactgggcac cttgaccagc aaataaaaag gctgttttag
     8401 tcatttctta caactcctgt ccagcgagag gcttcttctt gaattttctt agcggctccg
     8461 taatacaaat cttttaggat ttcttcagct gtttcttctt tagaaacaag ccctgcgatt
     8521 tgacctgcca tgacagagcc accctccaca tcaccgtgaa caactgcttt ggctagggca
     8581 ccggctccca tttgttcaaa gatttctaaa tcaggatctt cctgcttaaa ggcatctttt
     8641 tcagccagtt caaaatctct agtcaactga tttttaatag cacgaacagc atgaccaaag
     8701 tgctgagctg aaatcgtagt gtcaatatcc cttgctttta aaattttctc cttgtagttt
     8761 ggatgggcat tcgactcttt tgcaactaca aaccgtgtcc ccacctgtac agcctctgca
     8821 cctagcataa agccagccgc agcaccttca ccatccgcaa ttcctcctgc agcaataaca
     8881 ggaatagata cagctgtggc tacctgtcgc accaaggtca tggttgttaa tttaccgata
     8941 tgccccccag cttccattcc ttctgcaata acagcgtctg caccgatttt ttccatgcgt
     9001 ttagctaaag cgacactagg aacgacagga ataacgatta tcccagcttc atggaaacgt
     9061 tccatatact tgcttggatt tcctgctcct gttgtgacaa ctttaacacc ttcttcaata
     9121 acgagatcca cgatatcttc cacaaaggga gataagagca tgatgttgac cccaaagggt
     9181 ttatcagtca atgatttgat tttatcaata ttggccttga caacttcttt cggggcattt
     9241 cccccaccga taattcctaa tcctccagcc ttggaaacag cccctgccaa atcaccatca
     9301 gcaacccagg ccatccctcc ttggaaaata ggatagtcaa tcttcaataa ttctgtaata
     9361 cgcgttttca tagtgcctcc aaccttcctt gcttacgtaa tagttcgatt tcaccataat
     9421 ttgacagtca aactattacc taaacaagag ggagtgggtt tctccctact ccttctacta
     9481 atattctgct tattttgctt gctcttcaac gtaagcaacc aagtcaccaa ctgttttcaa
     9541 gtcattttct gcttcgattt ggatatcaaa agcatcttcg atttctgaga ttacttggaa
     9601 caagtccaat gaatctgcgt ccaaatcatc aaaagttgat tcaagtgtta cttctgatgc
     9661 gtcttttcca agttcttcaa cgataatttc ttgtactttt tcaaatactg ccatgatagg
     9721 actcctttaa aataaatagt ttttttataa caatgtgttc accacatgat tacctaaatt
     9781 gtaagaatga gcgtgcccca ggtcaagcct ccaccgaagc ctgatagaag aacagtctgg
     9841 ctaccatcta aagggatgag accttgttct acacactctg aaagtaaaat cgggatactg
     9901 gctgcactgg tattgccata ttccatcata ttggctggaa gtttggctcg gtcaacacca
     9961 atttttctag ccatcttatc caaaatacgg tcattggctt gatgaagtag cagataatcc
    10021 aagtctgtca cctctatagg agattcatca atagtctgct tgatagactt ggctacatct
    10081 cgaatggcaa aatcaaagac tgtgcgtcca tccatcttca aaaatgaatc tgcactttct
    10141 tgatctgaaa atggagaatg caaacctgaa tgcccataag ttaaacactc gctgcgactt
    10201 ccatcgctat tgagactctc agctaagaaa tgctcttgct cgctagcttc taacaagaca
    10261 ccaccagcac catctccaaa caacacagct gttgatcgat ccgaccaatc gactgcctta
    10321 gagagggttt cactaccaat caccaagcct ttttgaaagc gaccagaagc gataaacttt
    10381 tcagcagttg aaagagcaaa tacaaatcca ctgcaagccg cggttaagtc aaaagcaaag
    10441 gctttattag caccaatatt agcttgaaca cgagcagctg tagagggcat catcgaatct
    10501 ggagtaatgg tagctaggat gataaaatcc agttcttctc ctgttattcc agcttttgcc
    10561 atcagtttct tagcaacctc tgtagccaaa tcactggtag attctgttct tgaaatatgc
    10621 ctttgtcgta ttcccgttcg acttgaaatc cactcatcat tggtatccat aatctgagcc
    10681 aagtcgtgat ttgtaaccac ttgctctggc acataatgag caacctgact tatttttgca
    10741 aaagccatta tttcaaatcc tccaaaaatt ggtaaagatt agtcaagcct ttacccatga
    10801 cagcaatttc ttcctcgctc atgccatcaa taattttttc taccatggcc ttgtggaagc
    10861 gtttatgcag tctatgaatc aagcgaccct tctttgtcaa atgcagatgc accacacgac
    10921 gatcctgttc tgaccgaact cgctcaatgt agcccttacg ctctaaattg ttcaaacttg
    10981 tcgtaacagt tccaagagtt accatcaact cttttgacac ttgacttgga gtcacatctg
    11041 gagccttacc gatgacatca atcgtatgca tttctttgat ggagatatcc ttaaaacgac
    11101 tacctctcaa gttcacttcc tcaattacaa ggacattgtt aaatatagat gttaaatatt
    11161 cattgattcg ttggtagtcc atttttcata tccctccttc ttcaaaaaac ttttacaatc
    11221 aaaacatttg acagaaagaa ttatatcaaa attcaaagaa tgatgcaagt attttttatt
    11281 ttcctgtaaa tttaggtctt cttctctccg aatgagctcg cactccttct ttgaaatcct
    11341 ctgtttgagc taaggatttc tgtaggttca gttctaaagt agcgtaaccc tgccagtctt
    11401 taaattggct ctcccaaacc aacttcttaa tggcagcata ggaattactt gaagcacgtc
    11461 ttaatttttt aagaagctgt tctctcgtct tttcaagttt ttcagcttca gaaacgcggt
    11521 aaaccaaccc ccattctagg gctttttctg ccgttaaagc ctctcctgtc atagctaatt
    11581 gagcagcacg cgtcacaccg atactgcggc tcaagagatg aattccccct gcatctggag
    11641 ccaaaccaac accaacaaag gcttggataa acttagcctt atccgtcgcc aaacagaaat
    11701 ctgccgcaac agccatattc gctgcggcac ctgcaacagc accgtcaact tccattaaaa
    11761 caggtttggc tatttgcttg attttataag aaatcgtatt gaccaactct gcgatttttg
    11821 tcaatgatgg aatatcatcc tcatccactg cccgcttcat ctctaccaaa tctcccccaa
    11881 ctgagaagac cttcccattg gcattgatta agataaaatg cacagctgga ttttcttctg
    11941 ccaaagtcag agcttctaaa atctcctcac acatgggaat atgaaaacca tttgcgacct
    12001 caggacggtt caaggtaagg attgccaagt cctcttcaag ctgataaata atgtgttcca
    12061 tcagggctcc tttttatttt ataagcagtt tatactcttc gaaaatctct tcaaaccgcg
    12121 tcagcttcca tctgcaacct caaaacagta ttttgagctg acttcgtcag tcttatttac
    12181 aacctcaaag cagtgctttg agcagtctgc ggctagcttc ctagtttgct ctttgatttc
    12241 attgagtgtt aaattatttc actgtcaaag tatatctttt ttaggagcag aaagcaagaa
    12301 aaaatcgact gaaagtgtct cagccgataa gaaaggctcg ctttaggcta gaaagcatct
    12361 tattttcttc attgaaaaaa gcctttcttt ctgctataat cgtataaaat acttacttta
    12421 ggagttctta tgaaagttgt taaatttgga ggtagttctc ttgcctctgc tagtcaatta
    12481 gaaaaagttt taaacatcgt caaaagcgat tcagagcgtc gttttgtagt cgtttctgcg
    12541 cctggtaaac gcaatgctga agatactaag gttacggatg ccctgattaa atactaccgc
    12601 gactatgttg cgggtaacga tattagcaag agccaaagct ggattatcga ccgctatgct
    12661 gctatggtta gtgaattggg actaaaacca gctgtgctag aaaaaatttc taaaagtatt
    12721 cacgccttgg ccactcttcc tattgaagaa aatgaatttc tctacgatac tttcctagca
    12781 gccggtgaaa ataacaatgc caaattgatt gctgcctact ttaaccaaaa tggtatcgat
    12841 gcacgctata tgcaccctag agaagctggg attgtggtca caagtgaacc tggtcacgct
    12901 cgcatcattc catcaagtta tgacaagatt gaagaattga caaacaccaa tgaagtcctt
    12961 gtcattcctg gtttctttgg tgtcactaag gaaaatcaaa tctgtacttt ctcacgtgga
    13021 ggttctgata ttacaggttc tatcattgct gctggtgtca aagctgacct ctatgaaaac
    13081 tttacggacg ttgatggtat ctttgcagcc caccctggta ttatccacca accacactcg
    13141 attcctgagt tgacctaccg tgaaatgcgc gagttggcct atgcaggctt ctcagtcctt
    13201 catgacgagg ctcttcttcc tgcctaccgt ggaaaaattc ctctggttat caagaatacc
    13261 aacaaccctg accatccagg tactcgtatc gttctaaaac acagtaatga tgaatttcca
    13321 gttgtgggaa ttgctggtga ctcaggcttt gtcagcatta acatgtcgaa atacctcatg
    13381 aaccgtgagg ttggatttgg ccgcaaggtt ctgcaaatcc tggaagaact taacatcggt
    13441 tgggaacata tgccaacagg tatcgacgat ctttctatca ttctccgttc tcgccaacta
    13501 actcccatca aggaagaaga aatcctgcgt cagttggttc aaaaggctaa agtagatcat
    13561 gcagaaatcg aacacgacct ttctatcatt atgattgttg gtgaaaaaat gaagagccac
    13621 atcggagtga ctgctactgc gacacgcgct ctatctgaaa acaaaatcaa catccagatg
    13681 atgtctcaag gttctagtga agtttctatt atgtttgttg tcaataaaga ccaagagaaa
    13741 gcagcaatta aagccctcta caatgccttt tttggagaaa gtaaggaaga ctaagcatgg
    13801 cccaatcact taacaaaaca gtactcctca gtacgacagg cacttcctac ctctctatcg
    13861 ctgggaaagt tgggaaattc cttgtcggag atcaggcttt ggaattttac ccagatgtca
    13921 atgtcgaaca atttatccag attccttgga gccatatcaa tcagattgga gccaatgtca
    13981 ctggacgcaa aatcagccgc cacttcgaag tctttacaga caaaggaaaa ttcctctttg
    14041 cttcaaaaga ctcaggtgcc attctcaaaa ttgcacgcga aaaactaggc aatgacaagg
    14101 tcgtcaaact tccgaccctg attcagacaa ttagccaaaa atttaaaaat ctatttgcaa
    14161 aaaagtagaa actttagtat aatcatagca acggataagt aggttatctt cttctttcag
    14221 aaagtctgcg ggtactgcga gcagatagga gggataggtg aaattctacc gttagtaaca
    14281 attacataca caatcaagtg cacacctgtg aagttggatg gaaccgtggc cctgccactc
    14341 caacgttttg tcaggcgtgc ttttttcata aaggagttct tatgttagat atcaaacgta
    14401 ttcgtacaga ttttgaagct gtcgcagaaa aattagctac acgtggtgta gatgctgctg
    14461 tcttgaatga aatgaaagaa atcgatgcta aacgtcgtaa catcttgatt aaggttgaaa
    14521 ctctcaaagc agaacgtaac acagtttctg ctgagattgc ccaagctaag cgcaacaagg
    14581 aaaatacaga tgacaagatt gctgccatgc aaaatctatc tgctgaggtt aaagccttgg
    14641 atgctgaatt ggcagaaatc gatgctaaat tgacagaatt tacaacgact cttccaaata
    14701 tcccagctga cagcgttcct gttggggctg acgaagacga caatgtggaa gttcgccgtt
    14761 ggggtactcc acgcgagttt gacttcgaac ctaaagctca ctgggatctc ggtgaagacc
    14821 ttggtatcct tgactgggaa cgcggtggta aggtaacagg cgctcgcttc ctcttctata
    14881 aaggcctcgg tgctcgtttg gaacgtgcta tctacaactt tatgttggat gaacatggaa
    14941 aagaaggcta tactgaagtc atcacacctt acatagtcaa ccatgattct atgtttggta
    15001 ctggtcagta tccaaaattt aaggaagata cttttgaact cagcgatacc aactttgtct
    15061 tgattccaac tgctgaagtt cctctgacaa actactaccg tgatgaaatc ttagacggca
    15121 aagatcttcc aatctacttc actgccatga gtccgtcatt ccgttctgag gctggttctg
    15181 ccggtcgtga tacgcgtggc ttgatccgtt tgcaccaatt ccacaaggtt gaaatggtca
    15241 aatttgccaa accagaagaa tcttacgaag aattggaaaa aatgacagcc aacgctgaaa
    15301 acattcttca aaaactcaac cttccatacc gtgtcgttgc tctctctact ggagatatgg
    15361 gcttctcagc tgcgaagact tacgacttgg aagtgtggat tccagcacaa aacaattacc
    15421 gtgaaatctc aagctgttca aacacagaag atttccaagc ccgtcgtgcc caaatccgtt
    15481 accgtgatga agcagatggc aaggtgaaac tccttcatac cttgaacggt tctggacttg
    15541 cagttggacg tacagtggct gcaattcttg aaaattacca aaatgaagat gcttctgtga
    15601 ccatcccaga agcacttcgt ccatacatgg gtggagctga agtcatcaaa ccataaaaaa
    15661 taaggtttag ctatttctag ctagaccttt tttcgtaacc aaatcagata agcacctagt
    15721 acaaagaata aaatagttag gcatataatg gtttcagcca ataccaggta atccagaaat
    15781 ggaagtttca aaattccctg agccatcttg agcgaggtcg ctgtgataat ggttgggaag
    15841 gtgagggctg agaaggctgg ttgaaaacct tgttttaaaa tgttgggcag acgagttaaa
    15901 acaaagaaaa agaaggattg agaagccaaa atcatgacaa tcaagaccca agtcggcagg
    15961 ctggttcctc ctactcgaac tagagaagcc aagagtagag agaaaggagc acagtagatt
    16021 ccttcttgtc caagcaaggc tagtgggagt ggatgtttct ttaaatcgct ataaataagg
    16081 ggatagagat agaaggtcaa gagaaaacca aaactcaagg tcgcataggc aatttcgata
    16141 atacctacca gaggataggt caaggcagcc actgctatcc ccacatagag aaccgtccaa
    16201 cttggagtgg catgaaccct ccgccctgga caagcaaact tgatggtaaa accagcaatc
    16261 aaggtcaaat ccaagagaaa tgaaaaccac caaatccctt gtgctaccaa aggaagataa
    16321 gagaatacgc gaaagacata ggtcgataaa atcatcccag ccataggaaa ggttgccatt
    16381 cctgacaaaa gagggggctt ggtcaattct tgcttggttt ctttccaatt aaagagatgc
    16441 agaattagaa agtaaatcca taaaaccaaa ccagtcagac taaaaagatg ggatagaacc
    16501 ggcaacgtat ctaaaataag atttccagct cctgccaaac ctagcaaaca acctgaaaat
    16561 actaagggga gttttttcat cctaacctcc aataatcatg ttagtttcag tataacataa
    16621 aagcgcttaa atgaggattt aaaaaaacga agtccgctta tttcagactt cattttactc
    16681 agatatgaat taggcataag gttgcaattc tggattaatt ggtgtattag ctaagttgtt
    16741 ggcatagtta cagaggattg ctaggctgac accaaaaacc acatccaagg cattttgttg
    16801 agtgtagcca gcttctaaaa actcagacaa ggcttcatct cctacacgac ccttggtatt
    16861 gataactgcc aaggtaaact tagctagggt atccaattta ggatctgttt caattggagt
    16921 acgattgcga agagcttgaa tcaagtcatc attcatctgg atttgtttga tggaaaaggc
    16981 tgtgtgacct gcgacacaga aggcacaacc attggtcacg gctgccgtga tttgcaccac
    17041 ttcacgctca acgggtgtca ggctgttgcg acggtggata gatgagacaa tttgataggc
    17101 ttctaaaaca gtcggggcat tggccaagag accgattagg ttgggaatat agccattgtt
    17161 gtctttttct actgtttcaa gaatttcttt cacttctgct ggtgctgact ctactgtatg
    17221 gatagtaaat gttgtcataa gatacctctt ttcttattat tgacactaat attattggaa
    17281 aatcttataa aatcctgatt cctaagttta tctaagataa agctttattc tctcataaga
    17341 ttttcgttgt tatattagtt tatcacactt ccaatcactt gcataatata tattatatat
    17401 caggctgata aaaattattt ataggcaaaa aaatcacacg agctgtgtga ttccattatt
    17461 tgtcaaaata ctttttagtt tcagcaataa cgactggcga caagaccaag agggcaatca
    17521 agtttggcag agccatcaag gcgttaacga tatctgcgat aatccagacc atatccaact
    17581 cgataaatcc tcctaacaag accatgagca caaaaaccac acggtagagc cagataaagc
    17641 gaaccccaaa gaggaactca aaacagcgtt ctccgtaata gttccaacct agaatcgttg
    17701 taaaggcaaa aagtacaagg aagatggtca agagggcagg cccaaagtgt gaaaagactg
    17761 ttgagaaagc tgactgagtc aaggcaaccc cattcaagtc accactccaa actccagtta
    17821 ccaagatggt caaaccagtt agagtacaaa tgatgagggt atcaataaag gttcctgtca
    17881 tggaaatcaa accttgctct actggttcat ttgtcttggc agctgcagct gcaataggag
    17941 cagaacccag accagattcg tttgagaaca caccacgcgc cacaccattt tgaatagcca
    18001 tccgaacgct agcaccagca aatccaccta ccgcagcaag gggactaaaa gctgaggtaa
    18061 agactaaagc gattgtgcca gggatttttc cgatattaaa gaaaataact gtaagagttc
    18121 ctaagatata aatgatggcc ataaaaggaa caacagtagt tgaaacctta gaaatagact
    18181 tgagtccacc aaagactgca atcgctacaa agacagacaa gacgagagct gtgatggctg
    18241 gcgaaatcgt cgttgtattt tggatagatt ctgcaatcga gttgacttgg gtgaaggttc
    18301 cgattcccaa gagagcaacc aatactcctg ctactgcaaa caaaacagca agtggtcgcc
    18361 acttttctcc catccctaga aggatataat gcatgggacc tcccgctact gcaccatggt
    18421 cgtccttggt gcggtatttg atggccaaga gtccttccgc atacttggta gccattccaa
    18481 agaaagccgc catccacatc caaaatagag ctcctggtcc accaaccttg atagccgtcg
    18541 caactcctat gatatttcct gttccaacag ttgatgccaa ggctgtacac agagctgcaa
    18601 aactggatac atcaccatgt cccttatcct ggataaaaat aagctgaaaa gccttgggca
    18661 gacgcaaaac ctgcaagagt cctagccgaa tagttaggta aatccctgtt ccgaccaata
    18721 aaatcaagag gggcggtccc caagcaaaag catcgattga tttaagcaat tctaacattt
    18781 ccttctccta tcgtttcaac cccaaaagaa agagcacatg caagatacat gtactctgga
    18841 atgcttagat aaatgctaaa aagcggtcta tcctagctct gtccttttac ctgagagttt
    18901 gagcagttgc ctgccttgcc ccttcggtgc ctttacggtc tctccagagt tccgtccatt
    18961 tacagtcatg gaaaatcaaa cgattcccca cttctattaa acttcattcg gtgttggtat
    19021 ttaattgatt ctaattttac aaaaaatgtt ggcttttgtc aatgtgttta ttagtaaaaa
    19081 ttagttcaac agtttttact ttataaagtc cagaatactg ctatccttta aaagtgacaa
    19141 tagtcgcacc actgcctcca gcattttgtg gggcatagcc gaaactcttg acatgtttgt
    19201 ttctttgcaa gtatttggta actccttcac ggatgactcc tgttccgata ccatggatga
    19261 tatcaacttg agccatattg ttaagcaagg cttggtcgat gaaggtatct agctcattca
    19321 tggcttcttc atagcgcttg cctcgaagat ccagtctagc ttgaggtcct cgcccagaag
    19381 ttcgtttcac aacattgacc tgtttcttct tgactggttt ttcttgctgg gcttgaacaa
    19441 gatcaaactc tttctcttcc aaggtcatct taatcaagcc aacttgggct tcccagcggc
    19501 cgtccttgag ttgactggtc aaggtaccac gctgaccata actgagaacc acgatatcat
    19561 ctcccacctt tggagctcgt tttttcttgg ccttttgaag gaccttgttt ttagacaagt
    19621 ccactttttc aggagccaat tttttcaact tggccttggc ttcaatgatt tcgtggggct
    19681 tgagttggga tttactgtgg agatttttga gaatctggtc actttcactt agggccatat
    19741 ccacaatctc agcagcctgt tcacgcgcct tgttaagctc ggtttccttt tcacgattaa
    19801 gctcgttgta gagttttttt agcgcacggt tcatcttgag attttcttgc tccacctcac
    19861 ggatattgtc caagcgtttg cggctttcca gcgtctgctc ttctaattgc tcaatgatac
    19921 gattgacgtc attgtcctga tcgatctgct gactggcatc tcctacgata acttcagata
    19981 ggcctagacg tttggcaatt tcaaaggcat tacttcggcc aggaacaccc tgcataaagc
    20041 gataggtcgg gcgaagagtt gcagtatcaa actccatact ggcattttgc acaaaggctg
    20101 tctcaatacc gtaggccttg agttctggat agtgggtcgt cgccatggtc ttgatttgac
    20161 gcaggcgaag gtcctccaga atagccatgg caagggctgc tccctcttgg ggatcagtac
    20221 cagcccccaa ctcatccaaa agtaagagtg aatgttggtt gaccttgcca agaatatcca
    20281 cgatattggt catatggcta gagaaggtag acaagctctg ctcaatagac tgctcatctc
    20341 caatatcagc aaaaatttct tcaaaaatac caacacgact tcccttgtct gctaaaatcg
    20401 gcaatcctga ctgggccatg acctgtgtca agcccagagt tttgagcatg atggtcttcc
    20461 cacctgtatt gggacctgta atgacaatag ctgttaaatc ttgaccaaaa tagacatcat
    20521 ttgcgacggc atttttgacc aaaggatggc agacatggag cagttgaatc tcttgatttt
    20581 ctgacagctg aggcacgact gcttgtcttt cttggataaa tcgaaccttg gcacgaatca
    20641 agtccagatg accgataatc caagcatcat tagcaatctc agccgcatga gggcggacac
    20701 gctcagaaat ttcttggaga atgcgaagca tttcatagcg ctcatctgct cgcagactag
    20761 caatttcttc gctcagtttg actacctcac ggggttcgat atagacggtg tttccactag
    20821 cagaaatatc atgaacgaca cctgcaatct tattgcggta ggtgtttttg actggtaaaa
    20881 ccttacggcc atttctgcta gcaacaattc cttccgtcaa catctgcgct ttttgcttga
    20941 gcaagtcttg taaaacatcg cgtacctgac tctcgctatc atgtattttt cgacggattc
    21001 gcgccaattc ttcactggca aaattttcaa tgaaacccgc atcattaaag gcctgaagat
    21061 ttccttgtaa ttgcggaaaa tcatgtaatt tctcaaacca aagggctaat tcttccaagc
    21121 tgacattttc cagattggcg taaaaacttt gaagttctcg gctggcaaga agcacgcgtt
    21181 tcaagagtag gaactcctcg atattgagat ccgctcccat ctccaacctc ttgcagactc
    21241 ctgcaatttc cttagttgag agaatagtaa aatgcggttg ctcgacgaaa agagcctgca
    21301 tttccttcat ctcagcaaaa gcctgtttga ttttatctgc tttggcagtc ggagccagtt
    21361 gtctcaattg ctccaagccc tgctcggtca acaaatgagg ctcaaacaag gccttgacct
    21421 tatcgaactc taatgtttct aatattttct tattcatctt tatttccttg tctttgaatg
    21481 tctaggtgtg gtaacttttt acattctgat agattcaagt caaatctgta aacaaagggc
    21541 taggaaaact cctgcccttt ttatccgatt aaatttgtca cccagatttg tttgagccaa
    21601 ctggttgtta tcggtatgct ctggatgatg tgttttgcga cgatactctt ttcaagagga
    21661 ttttgtataa ctgccatggg gatggtcgcc aagattgtca aggccatttg caagacaaat
    21721 aaggtcacca acatggacaa gatacctgct gaaacttgga acaacttacc acccagtttt
    21781 ttgctaggaa tcaagtgtaa gagaagacca agcaaacgac caatgctata gacaatccca
    21841 aatacaagca agtagccgat acctgcataa aagaccttat ccagctgaaa gagttgatcc
    21901 gatgggaaaa agaaagtccc ctgaccttcc tgcgaatttg cataagggag caataaatgg
    21961 aattgctctc caagcccctt ataaaactgg ccagccataa aagccgatgc catggctgaa
    22021 atcaggtaat aaatctgtaa gagcaggcct ctccgatagc cgatataaaa tccccaaacc
    22081 aagaccaata gaagaaggaa tgaaatcata aggaatcctc aatcttgctc tgttcttgct
    22141 tacaagtcac aagcttgtga cggagttctt ctagctcttg ctccttatcg tcaaattcaa
    22201 tctcacggct gagctgagtt gataaacagt tgactgccaa caaaagagcg attgtttcat
    22261 catctgcgct aggcatttgt tctttaattg cttggtattt ttctgtcgca accttagcga
    22321 tttcctccat aaaaaggtta tcatgttcac ttgtcaaggt taacgatttt ttcccgaatg
    22381 taaatttgaa tcgatttaga tttgccataa aattcacctc acgatattat accaaaattc
    22441 gctaattttg tcagttttta caaattttac tgcttttgtg gtacaataga aactatggca
    22501 agtatcacac tcacaccaag cgaaaaggat attcaggctt ttcttgaaca ctatcaaacc
    22561 agtctggctc ctagcaagaa tccctatatc cgctactttt tgaaactacc tcaagcaacg
    22621 gtttctatct atacttctgg aaaaatcttg cttcagggtg aaggggctga aaaatacgcc
    22681 agtttctttg gctatcaagc tgtagagcaa accagcggac aaaatcttcc tttgattggg
    22741 acagatgagg tagggaatgg ttcctacttt ggtgggcttg cagttgtggc ttcctttgtc
    22801 acacctgacc agcatgcctt cttacgaaaa ctcggtgtgg gagattctaa gactctgacc
    22861 gaccaaaaga ttcgtcagat tgctcctatt ctcaaggaaa aaattcagca ccaggcactc
    22921 cttctctcac ccagcaagta caacgaggtc atcggagacc gctacaatgc tgtttcggtt
    22981 aaggttgccc tccataatca ggctatctat ctcctccttc aaaaaggtgt tcagcctgag
    23041 aaaattgtga ttgatgcctt taccagtgct aaaaattatg acaagtactt ggcacaagag
    23101 accaatcgtt tcagcaatcc tatcagcaat cctatcagct tagaagaaaa ggctgagggc
    23161 aaatacttgg ctgtcgcagt ttcttctgtc attgcgcgtg atctctttct ggaaaatctt
    23221 gaaaatttgg gacgagaact gggttatcag cttccaagtg gagctggaac ggcttctgac
    23281 aaggtggcta gccagatttt gcaagcctat ggtatgcagg gactcaactt ctgcgccaaa
    23341 ttgcacttta aaaatactga aaaagcgaaa aacgcttaga aaggtaagtt atgaatttat
    23401 ttaaaaattt cttaaaagag tggggattat tcctcctgat tctgtcatta ctagctttga
    23461 gccgtatctt tttttggagc aatgttcgcg tagaaggaca ttccatggat ccgaccctag
    23521 cggatggtga aatcctcttt gttgttaagc acctccctat tgaccgtttt gatatcgtgg
    23581 tggcccatga ggaagatggc aataaggaca ttgtcaaacg tgtcatcgga atgcctggcg
    23641 ataccatccg ttacgaaaat gataaacttt acatcaatga caaagaaacg gacgagcctt
    23701 atctagcaga ctatatcaaa cgcttcaagg atgacaaact ccaaagcact tactcaggca
    23761 agggctttga aggaaataaa ggaactttct ttagaagtat cgctcaaaaa gcccaagcct
    23821 tcacagttga tgtcaactac aacaccaact ttagctttac tgttccagaa ggagaatacc
    23881 ttctcctcgg agatgaccgc ttggtttcga gcgacagccg ccacgtaggt accttcaaag
    23941 caaaagatat cacaggggaa gctaaattcc gcttctggcc aatcacccgt atcggaacat
    24001 tttaagagac ctaagaggcc gagaatcacc aatctcagcc tcttcttcta tcgtgagaaa
    24061 atgattggta actatctaaa cttaccagaa cagaaacacc tcaactctca cctattcatg
    24121 caaaggaatt ttatggaagt ttatttttca ggaaccattg aacggattat ttttgaaaat
    24181 cccagcaatt tttatcgcat cctcctccta gaaatcgacg atacggacgc agaggatttt
    24241 gatgattttg aaatcattgt cacaggaacc atggctgatg taattgaggg cgaagactat
    24301 actttttggg ggcaaattgt ccagcactcc aagtatggag aacaactgca aatcagtcgt
    24361 tatgatcgcg caaaaccaac tagtaagggc ttggtcaagt acttttcaag tagccatttc
    24421 aaggggattg gtctcaagac agctcagaaa atcgtggata cctatggcga aaataccatt
    24481 gacgaaattt tgcaacaccc agaaaagtta gaaggcatcg caggactctc tgccaaaaat
    24541 cgcgaggctt tcgtctccac tctccgtctc aactacggaa cggagatggt tttggccaaa
    24601 ctagccaact acggcattcc caacaaacta gcctttcaga ttcaagactt ttacaaggaa
    24661 gaaacccttg atgtggttga aaattatccc taccagctgg ttgaggatat caagggtttg
    24721 ggctttacca ttgctgacca actagctgag gaactaggca tcgaaagtca ggctcctgaa
    24781 cgcttccgcg ccggtctagt tcacagtctt tttcaggcct gtatggaaac aggggacacc
    24841 tatgttgaag cacgggattt gctggaacaa acccttactc tccttgagtc ttcccgtccc
    24901 gtggaactag accccagcca agttgcccaa gagctctcct acctgatcga agaagacaag
    24961 gttcagcaga ttgataccaa gatctttgac aacagcctct ttttcgctga ggaaggcatc
    25021 cgcagtcact tggttcgtat ccttgaaaaa ggaaaacaga agagtcatga tttaaaaacc
    25081 attcaaaaac atatcactac tatcgagaaa gagcttggaa ttgagtatga taacattcaa
    25141 aaacaggcta tctgtgatgc tatccagaat aaggtcttta tcctgacagg tggacctggt
    25201 actggtaaga caactgttat caatgggatc atcgctgttt acgccctgtt agagggactt
    25261 gacctcagga agaaaagcaa cctgcccatt cttcttgctg ctccaactgg tcgagctgct
    25321 cgtcgcatga atgaattgac aggtttgcct agcgcgacca tacaccgcca cttgggaatg
    25381 acaggtgacg atgataccag tcatctggaa gattacctag atgctgactt tatcatcgtg
    25441 gatgaattct ctatggtgga tacttggctg gccaatcaac tcttctccag tatctcttct
    25501 aacagtaaga tcctcatcgt aggtgacagt gatcagctac cttctgtcag tcctggacag
    25561 gttctagcgg atctgcttca tattcctttg attcctcaga ctcgcttgga aaaaatttat
    25621 cgacaaagcg aagaatcaac catcgtcacc ctagctagtc agattcgaca gggcatcttg
    25681 ccagctgatt tcacccaaaa aaaagctgac cgttcctact ttgaaattgc tagtggccat
    25741 attcctgcca ccattgaaaa aatcttaggt gccgccctca gaaatggtat tcctgcccgt
    25801 gatatccaag ttctggctcc tatgtaccga gggacggcag ggattgatgc tatcaatcag
    25861 ctcatgcaag acctgctcaa tcccccacaa aaagatcaac tcagttttga agctcctcag
    25921 tgccactatc gtaagggaga caaggtcatt catttggtta acgatgctga aatcaatgtc
    25981 tttaatgggg atttaggagc tatcacagac ctgattcctg gtaaatacac cgaatcgaaa
    26041 caagacgaga ttgtcattga ttttgatggt aatgaagtct cttacccccg taacgaatgg
    26101 tacaagattc gcttggccta tgccatgagt attcataagt ctcagggaag tgagttccca
    26161 gttgtcatcc taccgattac tagtgctagc cgacgtatgc tggagcgaaa tctcatctac
    26221 acagccatta cacgtgccaa aagcaaactc atcttactag gcgaattaca agccttcgac
    26281 tatgctaccc aacacatcgg aactgcccga aaaacctatc tgattgaacg cttcagtgat
    26341 ctactggaga atgttgaaga aaagcaacaa gctgtctctg aaacagtcac atcaagtgcc
    26401 tctgaacaat cctacatcct aaccgaagaa aactgggaca gcattccagc catgattggg
    26461 attacagaca cagacctcaa agagattttt ggaaaatagt acatcagaaa acccaccaat
    26521 tcaggtgggt tttctgttta ttaagattat tttactgttg ctgtgcttgt gatcaattca
    26581 acagcttttt tgatagtgat atcatgtttc aacatgtcag ctgaaagcaa gttttgaact
    26641 tgtgcaactt ccatgttgta gtctgctgcc aattgctcaa cttctttttg gatttcttct
    26701 tctgaagcat caaatccttc agctttggca actgcttcga taacaaggtt agtcttagta
    26761 cgtgactcag cttctgcttg gtattggttg tgaaggtctt cttgagtagt tccagtgatt
    26821 tggaagtaca tgtcagggtt gatcccttga cgttgcaagt tcccaaggaa ttcatttact
    26881 gaacggtgaa cttcttcatg gatcatttct tctggaagtt ctacgatttc agcgttttct
    26941 acagctgtat caattgctgc accttcaact gcatctttgt aagcttcttc tttagcagca
    27001 gccaattctt tgcggtattt ttctttcaag tcagcaagtg tttcaacttc ttcatcaatg
    27061 tcttttgcaa gttcatcgtc aagagctgga acttctttag cttttacttc gtggatagtt
    27121 gtcacgaatt tagcttcttt acctgcaagg tcttctgctt ggtagtcttc tgggaatgtt
    27181 acgataacat caacggtttc gccagctgag tgacctacca attggtcttc gaaaccaggg
    27241 atgaattgac ctgaaccaag tccaagtgag aagttttcac cttttccacc gtcaaattca
    27301 acaccgtcga tagaaccaac gaagtcgatc acaacagtgt cgccgttttc agcagcagct
    27361 tccttgataa ccaattcagc caggttgttg cgttcgcgtt cgatacgctc ttcaacatca
    27421 gcgtcagtta cttctttttc tacatcaact gatacttcaa ggtttttgta gtcacccaat
    27481 tttacttcag gttttgtaac gacttcagca gcgataaccc agtcttgacc tttttccatt
    27541 gaagttacgt caatttttgg ttgggcaacc acttcaagac cagcttcttt tacagctgct
    27601 tcataagcgt ttggcaaaag agcgttcata acgtcttggt aaagtgattc ttcaccaaat
    27661 tttttatcga agataggacg tggaaggtga cctttacgga aacctggaac attaagagat
    27721 ttcttcactg acttgaagac acggtccaat tctggtttga tttggtcttg agagatagtg
    27781 aaagtcaaga caccacggtt tgtttctttg ttttcaaatg atacagacat tctgtcattt
    27841 ctccttaaaa ttttttaaat acagtctatt ataacatttt ctataaataa aatctagact
    27901 aatgcagcca attatagaca acaagccttt ttcctaacta aaacactcat aaagtataga
    27961 caattttaga ctactttgga tatcttttgg ttagtcattt tccaaaacta atttatctaa
    28021 tttttcagtt atatagtaga ttgaaactag aatagtacac ctctacttct aaaacatttt
    28081 tagaaatcgc tttgactgtc ctgatcgatt tgtcctgttc ttgtttcatt ttactatata
    28141 gatcgcattc gaaagaattc gttccaaaat tgcttggttc gttcttctct tggacgacta
    28201 aagaattgat gggcattatt tttttcaaca attttcccac cgtccataaa aataacatga
    28261 tgggctacat ctctagcaaa acctatctca taaagctgat caaaaactca atctgaggag
    28321 aaaatccaat aaggctttcc ataataaagg acatcctatc aagatttttg aacacccgat
    28381 aggctgcctt tttccgattt tgaagacttt ttgtccagct tcttttacct tataaataac
    28441 aacaaaaatc aaagacaagc tagaaagatt accgcagata actcaaacag tgttttgagg
    28501 ttgcagataa gactgacgga gtcagctcaa agcactgctt tgaggttgca gataagactg
    28561 acggagtcag ctcaaagcac tgctttgagg ttgtagatag aactgacgaa gtcagtaaca
    28621 tatgcctaag acaaagcgat gctaacctga tttgaagaga ttttcgaaaa atattaaata
    28681 tactctacaa tttgctcaat caattcttgg tcgtctaaac ctgtaacttg tataacaaca
    28741 tctttgactg attgtttagc caacaattca cctaatcgaa tactttcttc atcatttaca
    28801 tcgcgatagt caaaggcata gccaactgtt ttaagtaggt ttttatatga caaactgagt
    28861 tctttcaatt cacgtatcgg ccggatgaat cgttcattat agcctaattt tcggattgga
    28921 gtacgagcta cgcgactaac ctcgtccact atgaaagggt tttcaaaccg ttctataatg
    28981 actttgtgat aattctccaa ttctttttta tcaaagttcc atttggcaat caagagactc
    29041 cgaatttcag ctaatacaga ttcaatccga gatttaatat taggattttg aagagcttcc
    29101 aaaattgtct tggcaccata atgcgcacca atgtaagctg aagttgcatg tccagaattg
    29161 actgaaaaaa gttttcgctc aataaagggt tctaaatctt cttcataatg cacatctttt
    29221 agacgtaaat ctggattttt aagacgcttg gtttccacga cccattcatt aaagggctcg
    29281 accacaacaa aaagggaatc ttcgtgactt tgtgctggaa caatcctgtc tactgcagca
    29341 tttggaaaac ctatgtagtt atcagcaaat gtcaaacctt ccggacttaa atatttcttg
    29401 acttcttgat aaagaaattg agacccgcca atcatatttt cacaggccat aacatccaat
    29461 acctgtgtat tccctgcaac tcggcgagct tcgattcctt tggctagaag ttcagcgata
    29521 aaagggagta tattaggtcc gattgcagta gtaataatat ccgtcttttg aatcgcttca
    29581 atgacttgct caggatgttc tttgctatta attccagcca cattagttac ttctatacga
    29641 gaccgtcctt tctgtgcaat ttcaatttca tacttgccct tttcatttag agcatgaatt
    29701 atctgattat tgacatccac aaaatcaata tggaaaccat ttttaaatag aatttcacct
    29761 ataaaaccac gaccgatatt accggcacca aaatgaacag aatgtttcat tcaatttctc
    29821 cttttcctat ttgagggaca tatatactag atggcaaatg acgaaattca attattcaac
    29881 agcatcaaat aagcgcaata cttcctcttt tgactgagca tcggctaatt taagaacatt
    29941 atctacatct gcacagaaga tagaaatttt ctgaataatt tctaagtgtt cattaccaat
    30001 accagcaata ccaaaaagaa ccgttgccac ttgagggtta gatacattcc caaaatcaac
    30061 ccctctaggg acttgaacga ctgtaatacc agacttgagg acatcctttt ttgctgcatc
    30121 tgttccatgc ggtattgcga taaagttacc catgtaaaca gatagctctt tatctcgctc
    30181 aatcatggct tcaatatagt cttcattaac atatccaccc tcataaagaa cttgcccaca
    30241 ataacaaata gcttcctcct tgttagaaaa ttgtttatta agcttaatca aatgtttttc
    30301 aagtttcata ttagttctcc aatttcttaa ttttttcgtt aaaaatagta tttagcatct
    30361 gataaataat ggattgattt cccgtcttgt aaatctctgt ataaagatga ttttcaataa
    30421 tcgactgact aatagctgtc attaaatctc tcgcttcctc gctagcttct ttagacatta
    30481 gcattagcag acaccttttg acctcttctt cctctcgttt cattgacaat gcggagatag
    30541 gtagtttgag ttcaaacata gtaaaactat ttgttgttac tttgctagac tgactatgta
    30601 aaagcaccag accagtatta ggaatagcca taggactatt ctggaagtga gataacaatt
    30661 ttcttgttag gtaatctctg tcactcacat tcttctgata ttggatgatt tgttctaccg
    30721 tgtgctcaaa tgattgatta ttctccaatt gaaccaactc gaattgactc aaaagctgac
    30781 tactagatat taaataatct tgcaagtcat aacttttctc tggagcgata gcatcacgcg
    30841 cgacaattgt acgatgtgcc tgtacatact gaagtcgttc ctgtaattca agcaattctt
    30901 tgacggttgg aaaactagaa attacatcga tttcctgatt agtcagcggc ttggtagata
    30961 aaatataatc atactgactg agatcaatac tgtggtaatc tactagagac tgaatatcta
    31021 tcaactctac aaaaggagca acactcttaa ttttactgac taataaatct ctagtgaccc
    31081 gacgttcatc cgttaaaagc aaaacacgga ctggataaat ctctggacta cggcctaagc
    31141 tagagataaa atgtagggca atcatgccat actcatactc tgtatgaaga tatttcggaa
    31201 aaatatcatt cactaaaaga ctgatgactg tataaagaaa tttattcctt tcaactaaaa
    31261 tctggacaga ttctggcaaa ttttcaccct gaaaaaggat agggacgcct aaactgagcc
    31321 gaatatgatg gaaaagaaaa ttgaataaaa ccttgtcctt aaaaaagtca atcttggtat
    31381 acatggaaac cgtatcaatc agatttgaaa tattgtagaa aaattcacca tcaaatttct
    31441 ccgtaaagag cggattgtcc tgacgtttaa tgattaattc atccaagatg ctcgcaaaat
    31501 agataatttc ctgaatacta taaaattgtg cagtctgctt agagtaagct tgaaaaattt
    31561 tttgagaaat ttccaaagcc tgcttactag tattaggtga attttcaatg ttttgctcct
    31621 gacctataag agataacaag atcgcaaaaa acatcttcat cctagcatcc atatctggaa
    31681 aacctgacag ttgcttatta acaatctgac tggccagcct agttctatct gcttctaaaa
    31741 tatcaaagct cccaaaatta ccggttgaaa aatctgctac tgagatacag tttgtcagta
    31801 aaatagccaa aaatcttctc ttaccaactg aatcaccaga aatccgataa cctttttgtc
    31861 gttcaatttt cagatcaaag tctaaaagac gcttatcaat atctgaaata tcctgaataa
    31921 tagttacatt actgactttc gtgcactctt gcaatgcttc attggtgaca aaaccactct
    31981 cagtcagaag gcgataggta atcaactctt gtctttcttg gggactatac tcaactaaca
    32041 cttcaagttc tgtcggcaaa tcatccaact ctccagtcaa aatatagtat ttcccatgct
    32101 tcgttatttc gattccatat tgctccatgc tatctgtcaa atctgataaa gttcgataaa
    32161 ttgttctaga tgaaacctgt aagatttcag tcatatcttg cattgaaagc ttccctacat
    32221 gtaggaaagc cttcaataat tgttcttctc gtttggttaa tagcattcgt aatttagaaa
    32281 cctctagttc tatttgtaca ttctagcagc cattttgtca tattctggtg ttgttactaa
    32341 actatccaca ataagaaatt gagaattcgg tgctgcttgc tgcacttctg cctgtaaaga
    32401 aatagttgtt acaatcatta tgtttttaga attaaattca cctaattctg aaattttggc
    32461 agtagaaact ggaatacgaa tattcttgtt tctaaagata gcccgaatcg tttcacagcc
    32521 catagttgca gttccctgtg ctttaccata agcaactact acagcatcaa tatggttaag
    32581 gtcaatttcc tgactatcta ctggtgctga agttggtata tctccttcaa tttctgctat
    32641 tggaaaagct cctgttaatg aagctacaat ttcatcataa cgaggggacg ctaagaaatt
    32701 atcaacagaa acatgaatag cacttggact cttgtcttta gctcttggtg tcagttcttc
    32761 ctgagtaaca attaatgttt ttggtgtatc aagcaaattt gagattgcct gattagatac
    32821 tggaatctct agacctgctt ttttaacctt atctcgaaga atactagctc ccatagcaga
    32881 gcttcccata ccagcatcgc aggcgaaaat gattttttcc actgagtctg tcgaaataac
    32941 tgcatcaaca gaagttgata ctaactgacc tttagactga gctttagctg cttgggtagc
    33001 ctcttgagca gcttcgagcg aatcctcagt tgacttgtct gcatgaagaa taagggctgc
    33061 tacaaagaaa gaaacaactg ctgccactaa aacacctaga agaacattta gatggggcca
    33121 aacacctttt ggcgccgtag ccataatcgc aataatagaa cctggtgaag ctggagattt
    33181 aagaccagcg tctaagagtt gaaaagtaaa agttccagag atacctcctg ccatagcagc
    33241 taaaaataga gtaggcttca tcataacata aggaaagtaa atttcatgaa tccctccgaa
    33301 gaaatgaata accattgccc cccaagaaga agatttagca gaacctttac cgaatacagc
    33361 ataagctaat agaattccca ggcctggtcc aggattagct tccaatagga agagaattga
    33421 cttaccagct tgagctacct gttctactcc cagaggagta aaaatgccat gattgagggc
    33481 attattgagg aaaaggactt tagccggttc gatgataata ttagctatag gaaggaggcg
    33541 agcattgaca atagcctcaa caccattccc aacagctcca gtaagagtcg atacgactgg
    33601 accgattgcg tagaaagcca aaagcaataa tgcaaaacca acgagaccag ctgagaagtt
    33661 attaactaac atttcaaatc cgggacgaat tttttcctgg aacttctcat caaatttctt
    33721 gatagtccat cctcccagtg ggcccattac catagctccg ataaacatag gaacactaga
    33781 acctgtgatt gcaccaacag tagcaatagc tcctacaacg gcaccacgtt ggccatggat
    33841 catatatcca cctgtgtaac caatcaggat tggcaataaa tacgttaaca taggaccaac
    33901 aacagtagct aactgttcat ttggcagata gccatcagcg ataaagaggg cagtcaatac
    33961 tccccaagca ataaatgctc caatattggg cataaccata tttgaaagcg atgtccctag
    34021 tttttgaacc ctgactttca atgatacttt ttcttccatt agatcatcct ccttttctta
    34081 aaactagtat atacaaagtt aaaaaccttt aaaactaaag ttttgtcaca aattttgtgt
    34141 caaaacatta cttttgacga ggctgggcaa aaaggcttaa aaatgataaa acgcatcata
    34201 tccggtgtac
//
LOCUS       DAVLHM010000025        34037 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLHM010000025 DAVLHM010000000
VERSION     DAVLHM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34037
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.025"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            186..416
                     /gene="blpU"
                     /locus_tag="VXE45_001241"
     CDS             186..416
                     /gene="blpU"
                     /locus_tag="VXE45_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0789272.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1131..3284
                     /locus_tag="VXE45_001242"
     CDS             1131..3284
                     /locus_tag="VXE45_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0789273.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3297..4646
                     /locus_tag="VXE45_001243"
     CDS             3297..4646
                     /locus_tag="VXE45_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0789274.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4816..5523
                     /locus_tag="VXE45_001244"
     CDS             4816..5523
                     /locus_tag="VXE45_001244"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0789275.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5525..5668
                     /locus_tag="VXE45_001245"
     CDS             5525..5668
                     /locus_tag="VXE45_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0789276.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5725..9450
                     /locus_tag="VXE45_001246"
     CDS             5725..9450
                     /locus_tag="VXE45_001246"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0789277.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9543..10985
                     /locus_tag="VXE45_001247"
     CDS             9543..10985
                     /locus_tag="VXE45_001247"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0789278.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGVEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11204..12226
                     /locus_tag="VXE45_001248"
     CDS             11204..12226
                     /locus_tag="VXE45_001248"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0789279.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIAGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12223..12768
                     /gene="purN"
                     /locus_tag="VXE45_001249"
     CDS             12223..12768
                     /gene="purN"
                     /locus_tag="VXE45_001249"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0789280.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12852..13361
                     /locus_tag="VXE45_001250"
     CDS             12852..13361
                     /locus_tag="VXE45_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0789281.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13386..14933
                     /gene="purH"
                     /locus_tag="VXE45_001251"
     CDS             13386..14933
                     /gene="purH"
                     /locus_tag="VXE45_001251"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0789282.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            15055..16317
                     /gene="purD"
                     /locus_tag="VXE45_001252"
     CDS             15055..16317
                     /gene="purD"
                     /locus_tag="VXE45_001252"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0789283.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16720..17208
                     /gene="purE"
                     /locus_tag="VXE45_001253"
     CDS             16720..17208
                     /gene="purE"
                     /locus_tag="VXE45_001253"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0789284.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17195..18286
                     /gene="purK"
                     /locus_tag="VXE45_001254"
     CDS             17195..18286
                     /gene="purK"
                     /locus_tag="VXE45_001254"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0789285.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18296..18523
                     /locus_tag="VXE45_001255"
     CDS             18296..18523
                     /locus_tag="VXE45_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0789286.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18586..19884
                     /gene="purB"
                     /locus_tag="VXE45_001256"
     CDS             18586..19884
                     /gene="purB"
                     /locus_tag="VXE45_001256"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0789287.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19939..23877)
                     /gene="strH"
                     /locus_tag="VXE45_001257"
     CDS             complement(19939..23877)
                     /gene="strH"
                     /locus_tag="VXE45_001257"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0789288.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLETLDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(24192..24908)
                     /locus_tag="VXE45_001258"
     CDS             complement(24192..24908)
                     /locus_tag="VXE45_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0789289.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25256..27043
                     /locus_tag="VXE45_001259"
     CDS             25256..27043
                     /locus_tag="VXE45_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0789290.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            27040..27516
                     /locus_tag="VXE45_001260"
     CDS             27040..27516
                     /locus_tag="VXE45_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0789291.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27544..28449
                     /locus_tag="VXE45_001261"
     CDS             27544..28449
                     /locus_tag="VXE45_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0789292.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28436..29251
                     /locus_tag="VXE45_001262"
     CDS             28436..29251
                     /locus_tag="VXE45_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0789293.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29258..29662
                     /locus_tag="VXE45_001263"
     CDS             29258..29662
                     /locus_tag="VXE45_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0789294.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29915..31081
                     /locus_tag="VXE45_001264"
     CDS             29915..31081
                     /locus_tag="VXE45_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0789295.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31197..32234
                     /locus_tag="VXE45_001265"
     CDS             31197..32234
                     /locus_tag="VXE45_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0789296.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32442..33296
                     /locus_tag="VXE45_001266"
     CDS             32442..33296
                     /locus_tag="VXE45_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0789297.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33446..33703
                     /locus_tag="VXE45_001267"
     CDS             33446..33703
                     /locus_tag="VXE45_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0789298.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33811..>34037)
                     /locus_tag="VXE45_001268"
     CDS             complement(33811..>34037)
                     /locus_tag="VXE45_001268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789299.1"
                     /translation="TDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYKSPHN
                     KTHTIKVFMYCPPKVRQKESNFWGAVHFNT"
BASE COUNT         9467 a         6589 c         7980 g        10001 t
ORIGIN      
        1 tagtaaaaaa gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa
       61 agctaattca agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac
      121 tgttatacta aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat
      181 tcgttatgaa tacaaaaacg atgtcacaat ttgaaattat ggatactgag atgcttgctt
      241 gcgttgaagg tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag
      301 cagtacgagg tcttcagcta ggaattaaaa caagaacatg gcaaggtgca gcaactggtg
      361 ctgcgggagg agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat
      421 ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt atatggatga
      481 tttaattaga aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa
      541 ataatcaaaa ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag
      601 tcttatagta acgagtcaaa aaaggagtaa ctatgaatcg taatttagaa cggtgttatc
      661 tattctgact aggaatagat cataccagag gtagcttaga aatagcaggg acattagaaa
      721 ttgaagtaat aaataggatg tcgtaagtgt tactatcaat gatttatttg tttcaagctt
      781 gcctagggtg acagtaaaaa atcaatttcc tttcaatagc atatttttag tgggcaggac
      841 tcttgttctg cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg
      901 ggaaggaagt ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt
      961 atactcttcg aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact
     1021 gacttcgtca gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt
     1081 cctagtttgc tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg
     1141 ggaaacgtca ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca
     1201 tggtttttgg ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga
     1261 cgaccatgga tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg
     1321 agacgcgagc cattaaggcg gatatgacgc tttttgactt gccggatttg acttttcctt
     1381 ttgttgccca tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg
     1441 ataaggatag cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac
     1501 gtgagcgttt tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact
     1561 ataagcctta taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc
     1621 agcgtggctt gattgccaat atcgttttgg caacactctt ggtaaccggg attaacattg
     1681 tgggttctta ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga
     1741 cactagggat tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt
     1801 acgctcagga gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt
     1861 cctatatcaa gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg
     1921 agatcgtgtc tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc
     1981 tttcgatttt cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa
     2041 ataccaatct ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg
     2101 cctttatgaa gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt
     2161 cttcttctat cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa
     2221 gtcagcgtta ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct
     2281 atagtcgagc agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg
     2341 tcggcattct ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt
     2401 tgattaccta taataccttg ctggtttact ttaccaatcc tttggaaaat atcatcaatc
     2461 tgcaaaccaa gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag
     2521 tagcttctga gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata
     2581 tgaccttcaa gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca
     2641 atttaaccgt tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga
     2701 cgactttggc caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg
     2761 gtggtgtcaa tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc
     2821 ctcaacagcc ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg
     2881 aggggacgac acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata
     2941 tcgagcgcat gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag
     3001 gtggtcaacg tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga
     3061 ttttggatga ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc
     3121 tcatggcttt ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga
     3181 cagagaaggt agttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt
     3241 tgcttgcaca gggtggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga
     3301 aaccagaatt tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta
     3361 gtgtgattgt acccatggcc cttctgcttg tgtttttact tggctttgca actgttgcag
     3421 agaaggagat gagtttgtcc actagagcta ctgtcgaacc tagtcgtatc cttgcaaata
     3481 tccagtcaac tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta
     3541 agaaggggga tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct
     3601 atgccagtca gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga
     3661 gcctgcaaga aggggagaac cactttccag aggaggataa gtttggctac caagccacct
     3721 ttcgcgacta catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga
     3781 ccatcgcgtc ccagaatgca gcagctagcc aaacccaagc cgaaatcggc aacctcatca
     3841 gtcaaacaga ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggtg
     3901 cttccttggc cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg
     3961 aggaaaatcc ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt
     4021 tagaatctag tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct
     4081 atgcgtcagg gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg
     4141 gtcaggaatt gacccttcta gcccagaaaa ttttggaggc agagtcaggt aagaaggtac
     4201 agggaaatct tttagacaag gggaaagtta cggcgagtga ggatggggtg cttcatctta
     4261 atcctgagac cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc
     4321 catctttgga aagagaaggg aaagccaaac tcacagctta tctaagttca aaatatgtag
     4381 caagaatcaa ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaac
     4441 ttttcctaga ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga
     4501 atttctttaa aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt
     4561 acggggtgga aggccgcttg cagatgatta cgggcaagaa aagttaccta cgttattatt
     4621 tggatcaatt tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac
     4681 tgtgagaaag attcttcttg cagttttttc tttacaattt ttgaaaaaca tctactattt
     4741 attcggttaa attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga
     4801 aaggcgaact ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat
     4861 acaactgagg atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac
     4921 ggtgtcaaga aggagcagat tgcaggtaag ggagtcttga ataatcagat ctcatctttt
     4981 atttttgaga aattaaatgt ggctggtgtg gcgactcact ttgtggagaa actttcagac
     5041 acggaacaac tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat
     5101 actgctggtt ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg
     5161 attgtcgaat tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat
     5221 gtgaaattcc tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt
     5281 cgtatcaatg aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt
     5341 aagctagagt tcggttttga caaggatggc aagattatct tggcagacga attttcacca
     5401 gataactgcc gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga
     5461 ggattgggag aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa
     5521 taatctgttt gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt
     5581 cccccagacc ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt
     5641 ctgggaaaag ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga
     5701 gctgaaataa aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat
     5761 tttcaggtca agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc
     5821 ttgaaaagta ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt
     5881 gcacctgcag agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta
     5941 tctgtgcagg cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag
     6001 tttgaccagc gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac
     6061 gtgacagtca acacagccca actttacttg gtgaataaag atattgatgc gactgagttg
     6121 gaagctgtca aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca
     6181 gggattgcca agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt
     6241 gaaagctata cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa
     6301 gtggatgatt tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag
     6361 actgaactca aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag
     6421 acagagttga aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc
     6481 tatgacaagt atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg
     6541 atggatatgg cgactatttt cggtcgttat gagcgtgcta acggacgatt ggatgatatg
     6601 gaagtctctg acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc
     6661 aaggaacctt ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag
     6721 ccatttggtg gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt
     6781 tcctatgttt accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg
     6841 gaaactcgtg ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat
     6901 tcttcatatg gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca
     6961 ggctttgtag ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat
     7021 gttgtccgtg aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt
     7081 cgtgatggtg tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag
     7141 actgctggtg ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc
     7201 ttccgtaatg gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc
     7261 gtctgtgtgg ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct
     7321 cttaaatacc agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg
     7381 gcggtcgtgg ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat
     7441 attgatgctg ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat
     7501 ggtgagacaa tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt
     7561 gtcgatgcca aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct
     7621 gaaacactgg aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa
     7681 ggattacaga ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt
     7741 ggtcgttacc aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt
     7801 gtgactcata ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct
     7861 ccataccacg gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt
     7921 gccaactggt ctaaggctcg tttctcttac caagaatatt tcgagcggat ggacaagcaa
     7981 gcagagcgtt tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag
     8041 cttggcttgc catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc
     8101 gttccgccaa ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct
     8161 ccagaattta aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca
     8221 gagattgatt ttgacttgat taagaaaaat tttgctcagt ttgaagcaag ccaagctgac
     8281 cataaagtga cgtctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt
     8341 gctacctttg gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg
     8401 acagctcaat taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag
     8461 attggacaaa cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac
     8521 aagcttgaca gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa
     8581 gcgaaagaac tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa
     8641 aaggttgaaa aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat
     8701 tcagctaagg ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg
     8761 aatgaagaag ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat
     8821 attctcttct ttgccggtgg attctcggct gcggatgaac cagatggttc agctaagttt
     8881 atcgtcaata tcctgcttaa tgaaaaagtg cgtgtggcta ttgatagctt tatcgcccgt
     8941 ggtggcttga ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta
     9001 ccatacggaa actttgaaga tgctaacagt actagtccaa ccctcttcta caatgatgcc
     9061 aaccaacacg tggccaagat ggtggaaact cgtattgcca ataccaactc accatggttg
     9121 gctggtgtgc aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt
     9181 gtcgtgacgg ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac
     9241 gttgacttta acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat
     9301 gccatcgaag gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa
     9361 cgttatgagg atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca
     9421 tcagcggtta aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca
     9481 gtaatgtaaa agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa
     9541 aaatgacata cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac
     9601 atccagatgc tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg
     9661 agggggcagg aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc
     9721 ttttatcaga agttttcaga aatccagcca atttggataa attgacagga gctggtgcga
     9781 ttgggcatgt gcgttatgcg actgctggcg aagcttctgt tgataacatc caacccttcc
     9841 tcttccgttt tcacgatatg cagtttggtt tggctcataa tggaaatctg accaatgcag
     9901 cctctctcaa gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg
     9961 aaatcttggc tcacctcatt cgtcgcagtc ataatcctag cctgatgggc aaaatcaagg
    10021 aagcgctcag ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga
    10081 ttgcggctct tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag
    10141 cggtggttgt ttcctctgaa acctgtgctt ttgaggtcat tggtgtcgag tggatttgtg
    10201 atttgaagcc aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata
    10261 cagatgatac ccagttggcg atttgttcta tggagtatat ctactttgcc cgccctgatt
    10321 ctaatatcca cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc
    10381 gagaatttaa gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg
    10441 ctatgggatt tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat
    10501 acacccagcg aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga
    10561 aactgtctgc tgtttcgggt gttgtcaaag gcaaacgtgt ggtcatggtg gatgattcca
    10621 ttgtacgtgg aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg
    10681 aggttcacgt tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata
    10741 tccagacccg tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca
    10801 ttggtgcgga cagtctgact tatctttcaa ttgatggctt gattgagtcg attggtatcg
    10861 aaacagatgc gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc
    10921 ctctctatga ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca
    10981 agtaggcgac agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat
    11041 atgcctcacg tctcactact gactaaaggc ttaagcattt agtcagtaga cgctttgtcc
    11101 tataggatca aagctagagc cctgactagt atttttagat aaaaagatgg tttatctaaa
    11161 aatacgtcgc agtctttctc aaaaaaagaa aaggaaaaat aaaatggcaa ataaaaatgc
    11221 gtacgctcaa tctggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa
    11281 gcacgtggct cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat
    11341 gtttgacctt tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt
    11401 cggaaccaag ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg
    11461 tgtggccatg tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga
    11521 ctacgtagcg acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc
    11581 agaaggttgt gtgcaggctg gtgctgccct catcgctggg gaaacggctg aaatgccggg
    11641 catgtacggc gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc
    11701 tcaaatcatt gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag
    11761 tgggattcac tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga
    11821 ggaagtccta ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg
    11881 tatctatgtc aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca
    11941 catcacaggt ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc
    12001 tgaaattgat gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg
    12061 tcagattaaa cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc
    12121 ggtcagccct gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat
    12181 tggtcgcatc gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt
    12241 tttgcctctg gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt
    12301 gtcttttcag accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg
    12361 tcctatgctt ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc
    12421 gaactcttgg aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt
    12481 ggaccaacct tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg
    12541 ccagaatttc caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct
    12601 ggtgtgacca ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt
    12661 cgtgtgccac gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca
    12721 gagtacaggt tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat
    12781 tcatatgata tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg
    12841 aggtatttgt aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga
    12901 tgttattaac ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt
    12961 tcttagctcc aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa
    13021 aaattgtttt tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt
    13081 tccctttgat aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta
    13141 gtttattgtt tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt
    13201 tgactttaaa tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag
    13261 tgttcaaatc acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg
    13321 cttatcttgt tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga
    13381 atataatgac taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg
    13441 cccaagaact aaaaaaactt ggttgggaga ttatctcgac aggtggaact aaggttgccc
    13501 ttgataatgc tggggtggag accattgcga tcgatgatgt gacgggcttc ccagagatga
    13561 tggatggccg tgttaagact cttcatccaa atatccacgg gggtcttctc gctcgtcgtg
    13621 atttggatag ccacttggaa gcagccaatg agaaccaaat tgagcttatt gaccttgtag
    13681 tggtcaacct ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg
    13741 cagttgaaaa tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg
    13801 ccagtgttac agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag
    13861 caaacggcga aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca
    13921 cagcggctta tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc
    13981 ctgaaaaact cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc
    14041 aacaagacgc ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca
    14101 aacagctcaa cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc
    14161 gtatcatccg tgacttcaaa gatagtccaa ccgttgtggc tctcaagcat atgaatccat
    14221 gtggtatcgg ccaggcggat gacatcgaga cggcttggga ttatgcttat gagtctgacc
    14281 cagtgtctat ctttggtggt atcgttgttc ttaaccgtga ggtggatgct gcgacagctg
    14341 agaagatgca cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc
    14401 tagctatttt gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc
    14461 aagaggctag cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa
    14521 atcaagacgt ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa
    14581 ccgagacaga agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa
    14641 atggtattat cgtgaccaac gatcacatga cacttggtgt tggtccaggt caaaccaacc
    14701 gtgtggcttc tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc
    14761 ttgcttcaga tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa
    14821 ttaaggccat catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg
    14881 ataaatatgg cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata
    14941 aaagggaaga aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta
    15001 aaacgaactt ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa
    15061 ctgcttgttg tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca
    15121 aaagacgtgg aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg
    15181 gaattggtaa atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat
    15241 gatgttgctt ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat
    15301 tttaaccaag ctggacttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg
    15361 tccaaggatt tcgccaagga aatcatggtc aaatacggcg ttccgacagc aacatatggc
    15421 acattttcag atttcgagga agccaaggcc tatatcgaaa agcatggtgc gcctatcgta
    15481 gtcaaggcgg atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa
    15541 gcggtcgaag ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc
    15601 gtggttattg aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt
    15661 gataagttct acatcatgcc aacggctcag gaccacaaac gtgcctatga tggcgacaaa
    15721 gggcctaaca cgggtggtat gggtgcctat gcgccagtcc cacacttacc acagagtgta
    15781 gttgatacag cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt
    15841 cgcccttatc tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc
    15901 attgagttca acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc
    15961 tctgactttg ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg
    16021 acggacaagg gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat
    16081 gaaaggggcg ttgagttgcc agcaaagaca gaaggcgatg tcatcaccta ctatgcaggg
    16141 gctaagtttg cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc
    16201 gttaccacag cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa
    16261 caaaaaatag aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga
    16321 tataagaata acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca
    16381 gaacagtgaa tgttctggtc agggggaaac ttggagacct taggctcaaa gtttaggaat
    16441 gaaaccgaag gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa
    16501 aattcacaaa atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac
    16561 aatcaccgcc gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa
    16621 gaccttgggt ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa
    16681 gctaaggtga ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc
    16741 atcatgggct caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc
    16801 ttcggtgtag cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc
    16861 aaacatgcag aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc
    16921 gcagcgcatt tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca
    16981 gtcaagtctc gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt
    17041 ggggtgcctg ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt
    17101 gccctccgtc tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct
    17161 gaagaacaag gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat
    17221 tatcggtggc ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa
    17281 ggttatcgcg ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt
    17341 ggcaccttat aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac
    17401 ttacgagttt gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact
    17461 ccctcaagga acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt
    17521 gtcaaacaag gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt
    17581 ggcagatatc gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg
    17641 tcatggacaa aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga
    17701 ctcagcagac tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt
    17761 gtcaggaaat ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa
    17821 tatcctgtct aagaccatcg taccagcccg catttctgaa agtctagcag acaaggctaa
    17881 agctatggca gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat
    17941 gtttgcgact gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg
    18001 gcactattct attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct
    18061 cggagcacca ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg
    18121 tcagcatgtc gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat
    18181 gtatggtaaa atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga
    18241 tgtaccggat agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat
    18301 acaaattatc gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt
    18361 gtatgccagt gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata
    18421 ccccgaaaat tatttagcta tctatgatgt accgctggat acggatttga atacactaga
    18481 tcattacccg tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta
    18541 gatagcttat tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac
    18601 tctcgccctg agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag
    18661 gtggaaatcc tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg
    18721 gctttgattc gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag
    18781 acgcgccacg atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc
    18841 aagtgggttc actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc
    18901 tacaagcagg ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct
    18961 gacaaggcca aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct
    19021 gagccgacaa cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc
    19081 gagcgtttcg agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg
    19141 aactttgcca atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt
    19201 gcccaagaaa tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt
    19261 cttgccagca ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa
    19321 tctgagcaac gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg
    19381 cctcacaaac gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt
    19441 ggtcacatga ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac
    19501 tcatcagctg agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac
    19561 cgttttggaa atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg
    19621 aactcgactt ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc
    19681 atgacccgtg agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac
    19741 caagtagact ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa
    19801 gaagaaatcg atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt
    19861 gaacgtcttg gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt
    19921 attttttatc gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt
    19981 ggacatgagt cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt
    20041 tttctctgtt accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc
    20101 agttgatgga gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc
    20161 ttgtccgttt tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac
    20221 ggcttcctgt gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt
    20281 gctcacagag tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt
    20341 tcctttgagt aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg
    20401 gatatccagt ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg
    20461 agttacagga gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc
    20521 aaggactgtt tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc
    20581 acctttgact cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt
    20641 cttgataact tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac
    20701 attggcagcc acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc
    20761 ttgaagagcg gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt
    20821 gaggttgtaa tttagagctg ttttagctgc gtcaagggtc tcaagacttt ctttactata
    20881 tccttctaag tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg
    20941 gaagtagtct ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt
    21001 gtattcagcg cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc
    21061 tacttcagga tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat
    21121 agctttcttg aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc
    21181 accgttggta ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt
    21241 atatccccac cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc
    21301 gtccttgtct tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt
    21361 ggccatagct gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt
    21421 gaggtagtac cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt
    21481 gaaaatcttt gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa
    21541 gttcatcgct tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc
    21601 ttgaggattt ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg
    21661 actgttaata gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt
    21721 tacttctgcc tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc
    21781 gataatagct tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat
    21841 atcatcgagt agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc
    21901 gagctcactg gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc
    21961 agcatcgatt gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc
    22021 ttctttttga gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat
    22081 ggcttgatca atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc
    22141 tttttcagct tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg
    22201 tacctcgtta agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc
    22261 atttgcaaaa tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt
    22321 gtcagcccaa gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg
    22381 tacagaagtg attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc
    22441 ttggccatca gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg
    22501 gtgacctttt tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt
    22561 ccacatagaa acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta
    22621 gataccgtcg ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc
    22681 attggcgtag gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta
    22741 tttatcagct tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc
    22801 aagtccgatg ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag
    22861 ggcttttgta aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt
    22921 cccaaaatag ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc
    22981 atccatgtgt ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata
    23041 gttaatcaga tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata
    23101 atcatttgta cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt
    23161 agctgtgatg ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg
    23221 taaatcagtg tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga
    23281 gaaatattta cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac
    23341 agttgcagca cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc
    23401 atctttttta gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac
    23461 ctctttcgct tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt
    23521 ttcagcagaa gttggagtta ccacttctgc tttatcacta ggagttgaac taacttcctc
    23581 ttgtggtttt tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt
    23641 ttctacagtt tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt
    23701 ttcggatgat tgaggggaat cagaaaccgt atggatggtc ggttggtttt ctgtagtagt
    23761 aggagtaact ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga
    23821 agctgctcct acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc
    23881 aaaacctcct gattgcattg ttatattgat agcgattata taaatcaacg cctttatttt
    23941 atttcttata ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa
    24001 atataaaatt taaacttaag atttcagatt ggtcggaaaa aatgaatata tatatctagt
    24061 ataatttttg gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaatag
    24121 gtaagcgcta cctttttggt gtggtataat aagcatagaa aaagcccaag cgattagctc
    24181 aggctttctt cttagtgatc acggtcacat gagataaatt taatcttgta gtaatcagat
    24241 cgtttgtaag tttcactgta ttctaaaact tggccagttg attcgagttt ggtgatttta
    24301 gtttgtagga cagtagggaa ttgttcatcg actccgagga ctgaagccgc atgttctgga
    24361 gttggaaaga ctatttcgtt gatttcttca aagtgttcat cattcatgtg aatgtggtag
    24421 tctaacttga aacgattata gatagaacta tagtattcaa ggtttggata atttgcgttg
    24481 atatattgtt ctgggatgta ggatgtatgg tagatataaa cgacaccgtt tgattcgcgg
    24541 atacgttcaa tcttgtagta gaattgatcg ccgcgtagac ccaatttttc caagtaaaca
    24601 agcttgtttc cgcgttcaat tgaaagaaca gttaccttat catctttagc attgaagagt
    24661 tcaatatctg aaaactctac aagcttgtgt ttgcgcgcac gtgaaacgaa ggttcctttt
    24721 ccttgttggc ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg aacaactgtg
    24781 atagagctga catcgtacat tgaaatgagt tctgcttcag tgtaaaattt atctccactg
    24841 ctaaactgcc cagagatgat tttatttttt aattcgtctt ttatgtattg atatttggga
    24901 attgccatat ttttacctct attttccttc tccatagaaa attttaccat aaaagcgaaa
    24961 aaaatagtag tcttttgaat aaaaaattag aataatagtt tgaaaaatta agcgatatag
    25021 ggattgctca tattttataa atgtattcta tacaaaatta ttttaggtcc tatattccga
    25081 atttaaagag cgtttgaaat gggtctaaaa atgtttgaaa ctaattgaat gtgtgtataa
    25141 tagtaaaaat gcagtaaata tcccgacaat ttctattgac aattcaaaca gattggttta
    25201 taattaatat aacaacaaat gaaagcgcaa actttcgcgg tcggaaggta gttttatgac
    25261 acgatttgag atacgagatg atttctatct cgatggaaaa tcatttaaga ttttatctgg
    25321 tgccattcat tattttaggg ttcctccaga ggattggtat cattcgctct ataacttgaa
    25381 ggctcttggt tttaatacgg tagagactta tgttgcttgg aatttacacg agcctcgtga
    25441 aggtgagttt cattttgacg gtgatctgga tttagagaaa tttctccaaa tagcgcagga
    25501 tttgggtctc tacgcaattg tgcgtccgtc tccatttatc tgtgcggaat gggaattcgg
    25561 tggcttacca gcttggctct tgaccaagaa catgcgaatt cgctcatccg acccagcata
    25621 tatcgaggca gttggtcgct actatgatca gttattgcca agactggttc ctcgtttgtt
    25681 ggacaatggt ggcaatattc tcatgatgca ggttgaaaat gagtatggtt cttacggaga
    25741 agataaggct tacctgagag cgattcgaca gctaatggaa gagtgtggcg taacctgtcc
    25801 cctctttaca tcagatggtc catggcgagc tactctgaaa gctggaacct taattgaaga
    25861 ggacctcttt gtaacaggaa actttggttc taaggcacct tacaactttt cgcagatgca
    25921 ggaattcttt gatgaacatg gtaagaaatg gccactcatg tgtatggagt tctgggatgg
    25981 ttggtttaat cgttggaaag aaccgattat cacacgggat cctaaggaat tggcagatgc
    26041 agttcgagaa gttttggaac aaggctccat caatctttac atgttccacg gtggtacaaa
    26101 ctttggtttc atgaatggtt gctcggctcg aggaactttg gacctgccac aagttacgtc
    26161 ttatgattac gatgcccttc tggatgaaga aggaaatcca actgctaaat atcttgcagt
    26221 caagaagatg atggcaacac atttttcaga gtatccgcag ttggaaccac tctacaaaga
    26281 gagtatggag ttggatgcta ttccactagt tgaaaaagtt tctttgtttg aaaccttaga
    26341 tagcttgtca agtcctgtag aaagtctcta tcctcaaaag atggaggagc tgggacaaag
    26401 ttatggctac ctactttatc gaacagaaac aaactgggat gcagaagaag aaagacttcg
    26461 tatcattgat ggtcgagata gggcccagct gtatgtcgat ggtcagtggg ttaaaactca
    26521 atatcagaca gagattgggg aagatatttt ttatcaaggt aaaaagaaag ggctatctag
    26581 gttagatatc ttgatagaaa atatggggcg tgtcaactat gggcataagt tcttagcgga
    26641 tacgcaacgt aagggaattc ggacaggggt ctgtaaggat ctgcatttct tactaaactg
    26701 gaaacactat ccactcccac tagacaatcc tgagaaaatt gatttttcaa aaggatggac
    26761 tcaaggacaa ccagcctttt acgcttatga ctttacagtc gaagagccaa aagatactta
    26821 cctagacttg tctgagtttg gtaagggggt tgcctttgtc aatgggcaga atctaggacg
    26881 tttttggaac gttggcccaa ctctctcact ttatatccct catagctatc tcaaggaagg
    26941 tgccaaccgc atcattatct ttgaaacaga aggtcaatat aaagaagaga ttcatttaac
    27001 tcgtaaacct acactaaaac atataaaggg ggaaaactta tgacaattgt aggatgccgt
    27061 attgatggac gtttgatcca cggacaagta gccaatcttt gggctggaaa actaaatgtt
    27121 tcacgcatta tggttgtaga cgacgaagtt gtcaacaacg atattgaaaa gagtggtttg
    27181 aaacttgcga caccaccagg tgtgaaattg agtattttgc cagttgagaa agctgcagcc
    27241 aatattcttg ctggcaaata cgatagccaa cgtctcttta tcgtggctcg taaaccagac
    27301 cgcttccttg gtttggtaga agcaggtgta ccacttgaaa cccttaatgt tgggaatatg
    27361 tctcaaacac cagaaactcg ttctattaca cgttctatca acgtagtaga caaggatgtg
    27421 gaagacttcc acaaactggc agaaaaaggt gttaaactta ctgctcagat ggttccaaat
    27481 gatccaattt cagacttttt gagcttatta aaataggaaa aaatttttta ggaggtcatt
    27541 gttatgatac aatggtggca aattttactt ctcactttgt actcagctta tcaaatctgt
    27601 gatgagttga cgatcgtttc atctgcaggt tcccctgtat ttgctggttt cattactggt
    27661 ttaatcatgg gagatgtgac tactggttta cttatcggtg gtaacttgca actgttcgtt
    27721 cttggggttg gtaccttcgg tggtgcttct cgtatcgacg caacttctgg tgcggttctt
    27781 gcgacagcct tctctgtttc acaaggaatt gatgcaccgc ttgcaattac tacaatcgct
    27841 gtaccagtag cagctctctt gacttacttc gacgttcttg gtcgtatgac tactaccttc
    27901 ttcgctcacc gtgtggatgc tgcaatcgaa cgctttgact ataaaggtat tgaacgcaac
    27961 tacttgcttg gtgcgattcc gtgggctcta tctcgtgccc ttccagtctt ctttgccctt
    28021 gcttttggtg gtgcctttgt acaatcagta gtagacttcg ttgaagccta caaatgggtt
    28081 gcagatggct tgacactcgc aggacgtatg cttccaggtc ttggatttgc aatcttgctt
    28141 cgttaccttc cagttaaacg taaccttcac taccttgcta tgggatttgg tttgacagct
    28201 atgttgactg ttctttactc atatgtaaca ggtcttggtg gcgctgttgc tggtatcgta
    28261 ggtactcttc ctgctgaagt tgctgaaaaa attggtttcg tgaacaactt caaaggtttg
    28321 tctatgattg gtatttctat cgtaggtatt ttccttgcag tgcttcactt caaaaatagc
    28381 caaaaagtag ctgtagcagc accttctaca ccatcagaaa gtggggaaat cgaagatgac
    28441 gaattctaat tacaaactta caaaagaaga ttttaatcaa atcaacaaac gtagcttgtt
    28501 tactttccaa ttaggttgga actacgaacg tatgcaagct tctggttacc tttacatgat
    28561 cttgcctcag ttgcgtaaaa tgtatggtga tggaactcct gaattgaaag aaatgatgaa
    28621 agttcatact caattcttca atacttcacc attcttccat accattatcg ctggttttga
    28681 ccttgccatg gaagaaaaag atggtgtagg ttcaaaagac gctgttaacg gtatcaagac
    28741 aggtttgatg ggaccattcg ctcctcttgg ggatacaatc tttggttcac ttgtacctgc
    28801 tatcatgggg tcagtcgcag caactatggc tatcgctggc caaccttggg ggatcttcct
    28861 ttggattgca gttgcagtag cgtatgacat cttccgttgg aaacagttgg aatttgctta
    28921 caaagaaggg gttaacctta tcaacaacat gcaaagtacc ttgacagctt tgattgacgc
    28981 tgcatctgta cttggtgtct tcatgatggg tgctcttgta gcaacagtga ttaactttga
    29041 aatttcttac aagttgccaa tcggtgaaaa gatgattgat ttccaagaca tcttgaacca
    29101 aatcttccca cgtttgcttc cagcaatctt tactgccttt atcttctggt tgcttggtaa
    29161 aaaaggtatg aactctacta aagctatcgg tattattatc gtacttgctt tggctctttc
    29221 tgcccttggt cactttgcac ttggaatgta attccttatg actaaatcat taattttggt
    29281 gagccatggt cgcttctgtg aggagcttag aggtagcaca gaaatgatta tgggcccaca
    29341 agacaacatt tacacagtag ctcttcttcc agaagatggc ccagaagaat ttactgctaa
    29401 atttgaagct gttattgaag gattggatga tttcctagtc tttgcggatc ttctcggtgg
    29461 gacaccttgt aatgtggtga gtcgcttgat catggaaggt cgtgatattg acctttacgc
    29521 agggatgaat cttccaatgg tgattgaatt tatcaatgcg agccttacag gcgcagatgc
    29581 ggactacaag agccgtgctg cagaaagcat tgtgaaagtt aatgacctgt tagcgggctt
    29641 cgatgatgac gaagatgaat aatactcttc gaaaatctct tcaaactacg tcaacgtcgc
    29701 cttgccgtag gtatatgtta ctgacttcgt cagtcttatc cggcaacctc aaagcggtgc
    29761 tttgagcagc ctgcggctag tttcctacag attttagttg gaactcgatt caattcatgt
    29821 gacaacgtga aaatcgttag agcattttat atagaatata catgggaatg gagcttactc
    29881 ccattcccat atttaataga aaaagaggaa ctcaatgcta cattatacaa aagaagactt
    29941 gctcgaattg ggtgcagaaa tcactacgcg tgaaatctac caacagcctg atgtatggag
    30001 agaagctttt gaattttatc aagcaaaacg tgaagaaatt gcagcctttc tacaagaaat
    30061 cgctgataaa catgactata ttaaggttat cttgacaggt gctgggactt ctgcttatgt
    30121 gggagatacc ttgctacctt actttaagga agtctatgac gaacgcaaat ggaatttcaa
    30181 tgctattgcg acaacagata tcgttgccaa accagcaacc tatttgaaaa aagatgtggc
    30241 aactgtcctt gtgtcttttg ctcgtagtgg gaactcgcct gaaagtgtgg cgactgttga
    30301 tttggccaaa tccttggtgg atgagcttta tcaagtgacg attacttgtg caacagatgg
    30361 taaattggct cttcaagctc acggtgatga ccgtaatctc ttgctcttgc aaccagctgt
    30421 ctctaatgat gctggatttg ccatgacttc tagctttacg tctatgatgt tgacagctct
    30481 cttggtcttt gatcctacag aatttgctgt taagtctgaa cgttttgaag ttgtatctag
    30541 tcttgcccgt aaagttttag acaaggtaga agatgtcaaa gagctcgttg atttagactt
    30601 taaccgtgtc atctatctag gcgctggtcc tttctttgga cttgctcatg aagctcagct
    30661 caagattttg gaattaactg ctggtcaagt tgcgaccatg tatgaaagcc cagttggctt
    30721 ccgtcacggt ccaaaatctc ttatcaacga caatacagtt gttttggtct ttggtacaac
    30781 gacagcctac actcgtaagt acgacttgga cttggttcgt gaagttgctg gtgaccagat
    30841 tgctcgtcgt gttgtgcttt tgagtgatca agcttttggt cttgaaaatg tcaaagaagt
    30901 ggtccttggt tgtggcggtg tcttgaatga tatttaccgt gtcttccctt acatcgttta
    30961 tgcccaactc tttgctctat tgacttcact caaggtagaa aataaaccag atacaccgtc
    31021 tcctacaggt acagtaaacc gtgtagtaca aggtgtcata attcacgaat atcaaaagta
    31081 agacagtgtt tatgaattct tgacaagagg atttgtaaat tatcagataa accatagatt
    31141 gtcagtacgc tttctatggt ttgtttgctt gagagaaata gtaaaaggag aacagaatga
    31201 aagcatacac agagcgtgta tttggaaatg ttgagggcga ggatgtcttg gcctatcgat
    31261 ttgagacaga cggtggctac caacttgagg ttatgactta tggcgcgacc atcttgcgct
    31321 atgtcgcacc tgacaaggct ggaaattttg ccaatgttat cttgggattt gatgactttg
    31381 atagttatgt aggcaatagt cccaagcatg gagcaagtgt aggtcctgta gcgggtcgta
    31441 ttgcaggtgc gacctttgag ctcaatggta agacctatga ccttgaggtt aataatgcta
    31501 gcaactgtaa tcacagtggt tcaactggtt gggattccag cttgtttgaa gttgaagaag
    31561 taagcgatca tggcttgact ctctacacag agcgtacaga tgggacagga gggttccctg
    31621 gaaatctcaa gatttggatc agttatcact tggaagaaac tggtgcctat gaaatcatct
    31681 acaaggtaac gaccgatcag gatacgctgg tcaatccaac caaccacagc tatttcaact
    31741 tgtctggtga tttcacgcag acgattgacc gtcatgtctt ccaactaaac acagagggca
    31801 tttactcaat cgctcctgac ggtgttcctg ccaaaactcc agaagccaac cgtgatgtgg
    31861 tcaaacacat ctacaatggt accttgttga aggatatctt tgcagaagaa gatgagcaaa
    31921 tccagctggc atcaggtttg gatcacccat ttgcccttcc tgcaggccat gacaatgctg
    31981 gattccttta tgaccaaaat tcaggtcgct tcctgctttt caagacagaa gctccttgct
    32041 ttgtggtcta cacagcaaac tttgtggatg aaagtgtcat cataggaggt cagccaatgc
    32101 tacagcacaa tgggattgct cttgaagcgc aagctttacc agatgccatt cacagtgacc
    32161 ttaaaggcca agtcattctt aaagctggtc aaaccttcac cagtaagaca cgttatgaac
    32221 ttgttgtgaa ataaaaaaag ctggtcaaaa agtctttaaa attaaaataa cgcatattgt
    32281 caggtgatga aaagtttgat aatatgcgtt ttattatgaa atgatttact ttatcttatc
    32341 ctgaaatggt gttatttttg agttatctgg cttgactttc ttgatggaaa ttatataata
    32401 gttgtaataa caataattac aacgagaaaa gaggaccatt tatgacctat gaatacaaga
    32461 gtcacattta tttggcagag acagttttaa atgtaaagga tttggccagt caaacagcct
    32521 tttatcagca agttattggt ttagaaatct tatctcaaac tgagacagag tccattctag
    32581 gccttggtgg aaaagtcttg gtacagctga ttcaagcaca agagagcgga gaagtgaggg
    32641 aacattatgg tctttaccat ttggccattc tcttgcccac acgcaaggct ttggctgatg
    32701 tcttgaaaca cctgacagat ttgcaaattc ctcttgtcgg cggtgcagac catggttaca
    32761 gtgaagctat ttacttggaa gatttggagg gaaatggcat tgaactctat cgagataagc
    32821 cagtttccac atggaatatt cgagaagatg gacgcattat cggagtgacg gaggctcttg
    32881 cggcgcagga catttatgag ttgggggaaa gagtagagcc ctttatcctg gcagaaggta
    32941 caagaatggg gcatattcat ctttccgtca aggatagtcg aaagtccagc cagttttatc
    33001 aaaaggtgtt agggctagag aataaattca gtgtgcctgg cgctagttgg attgcggctg
    33061 gagattacca tcatcattta gcagttaacg aatggggagg aaaaggtctg gcttcgcgta
    33121 agcaaggctt accaggttta gcctactatg tcatcgaagt cgcacataaa aaagaactgt
    33181 taacgattgc ccaacgagca caagaagttg acgcaccaat caaatggatg acatcgagcc
    33241 aattggaaat cacagactca gatggcatcg tgacccgtat tcgtttagca aggtaaaatt
    33301 aggaattttt aataagttat aagtattgct agtttgcttt ttgaacggtc tttggtaaca
    33361 gaactgcgtg agctggatgg gtgagaattt tgacaaagaa gctgattaga gatataatga
    33421 agaaaaatcg agcaaggaaa aagaaatgac aaattcaaag tatattactt gtttgaaacg
    33481 ttcagagggc cagttgtgtg gaattcaaaa gatgattgaa ggagatcgtg actgtgctga
    33541 tattgtgacg caactgacag cagtgaaatc tagtgtagag cgcgtgattg agatgataat
    33601 taccgaaaat cttactgaat gtatcaatca gccactagat gattctgaag ctcaaaagga
    33661 acgcctagaa aaggctatcc gatacttgat taaacggaaa taaatgaatg ttttgagacg
    33721 atatgtgcaa aggtctatta actattagaa tagtttaatg tgagtcaaaa gaagttgtaa
    33781 aaaatcttta aaattaaaaa acgcatagta tcaggtattg aaatgtactg ccccccaaaa
    33841 gttagattct ttctgtctaa cttttggggg gcagtacata aaaaccttga tagtatgcgt
    33901 tttattgtgg ggagacttat actcttcgaa aatctcttca aaccacgtca gtttcacctt
    33961 gccgtagata tggttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga
    34021 gctgacttcg tcagttc
//
LOCUS       DAVLHM010000026        33074 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLHM010000026 DAVLHM010000000
VERSION     DAVLHM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.026"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            118..876
                     /locus_tag="VXE45_001269"
     CDS             118..876
                     /locus_tag="VXE45_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0789300.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            878..1327
                     /locus_tag="VXE45_001270"
     CDS             878..1327
                     /locus_tag="VXE45_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0789301.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            1389..2015
                     /locus_tag="VXE45_001271"
                     /pseudo
     CDS             1389..2015
                     /locus_tag="VXE45_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            2083..2331
                     /locus_tag="VXE45_001272"
     CDS             2083..2331
                     /locus_tag="VXE45_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789302.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            2462..3634
                     /locus_tag="VXE45_001273"
     CDS             2462..3634
                     /locus_tag="VXE45_001273"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0789303.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            3634..4908
                     /locus_tag="VXE45_001274"
     CDS             3634..4908
                     /locus_tag="VXE45_001274"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0789304.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQDDPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(4944..5909)
                     /locus_tag="VXE45_001275"
     CDS             complement(4944..5909)
                     /locus_tag="VXE45_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0789305.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVTTTGYFLPVTLLPGKSI"
     gene            complement(5890..7344)
                     /locus_tag="VXE45_001276"
     CDS             complement(5890..7344)
                     /locus_tag="VXE45_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0789306.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            7720..9603
                     /locus_tag="VXE45_001277"
     CDS             7720..9603
                     /locus_tag="VXE45_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0789307.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            9752..10639
                     /locus_tag="VXE45_001278"
     CDS             9752..10639
                     /locus_tag="VXE45_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0789308.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(10682..11299)
                     /locus_tag="VXE45_001279"
     CDS             complement(10682..11299)
                     /locus_tag="VXE45_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0789309.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(11714..11902)
                     /locus_tag="VXE45_001280"
                     /pseudo
     CDS             complement(11714..11902)
                     /locus_tag="VXE45_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(12412..12492)
                     /locus_tag="VXE45_001281"
                     /pseudo
     CDS             complement(12412..12492)
                     /locus_tag="VXE45_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            12608..13501
                     /locus_tag="VXE45_001282"
     CDS             12608..13501
                     /locus_tag="VXE45_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789310.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            13498..14697
                     /locus_tag="VXE45_001283"
     CDS             13498..14697
                     /locus_tag="VXE45_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789311.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(15050..15817)
                     /locus_tag="VXE45_001284"
     CDS             complement(15050..15817)
                     /locus_tag="VXE45_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789312.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(15834..16529)
                     /locus_tag="VXE45_001285"
     CDS             complement(15834..16529)
                     /locus_tag="VXE45_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789313.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(16534..16899)
                     /locus_tag="VXE45_001286"
     CDS             complement(16534..16899)
                     /locus_tag="VXE45_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0789314.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            17039..17512
                     /gene="nrdR"
                     /locus_tag="VXE45_001287"
     CDS             17039..17512
                     /gene="nrdR"
                     /locus_tag="VXE45_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0789315.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            17513..18682
                     /locus_tag="VXE45_001288"
     CDS             17513..18682
                     /locus_tag="VXE45_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0789316.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            18683..19579
                     /gene="dnaI"
                     /locus_tag="VXE45_001289"
     CDS             18683..19579
                     /gene="dnaI"
                     /locus_tag="VXE45_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0789317.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            19576..20289
                     /locus_tag="VXE45_001290"
     CDS             19576..20289
                     /locus_tag="VXE45_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0789318.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAKMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            20303..21613
                     /gene="der"
                     /locus_tag="VXE45_001291"
     CDS             20303..21613
                     /gene="der"
                     /locus_tag="VXE45_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0789319.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            21704..22039
                     /locus_tag="VXE45_001292"
     CDS             21704..22039
                     /locus_tag="VXE45_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789320.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            22224..23015
                     /locus_tag="VXE45_001293"
     CDS             22224..23015
                     /locus_tag="VXE45_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789321.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILHVVPYMVLKKYEDNV"
     gene            23008..23649
                     /locus_tag="VXE45_001294"
     CDS             23008..23649
                     /locus_tag="VXE45_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789322.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            23653..24303
                     /locus_tag="VXE45_001295"
     CDS             23653..24303
                     /locus_tag="VXE45_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0789323.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            24314..24601
                     /locus_tag="VXE45_001296"
     CDS             24314..24601
                     /locus_tag="VXE45_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789324.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            24747..27260
                     /gene="secA"
                     /locus_tag="VXE45_001297"
     CDS             24747..27260
                     /gene="secA"
                     /locus_tag="VXE45_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0789325.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            27341..28372
                     /locus_tag="VXE45_001298"
     CDS             27341..28372
                     /locus_tag="VXE45_001298"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0789326.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            28374..29405
                     /locus_tag="VXE45_001299"
     CDS             28374..29405
                     /locus_tag="VXE45_001299"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0789327.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            29444..29812
                     /locus_tag="VXE45_001300"
     CDS             29444..29812
                     /locus_tag="VXE45_001300"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0789328.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            29802..30905
                     /locus_tag="VXE45_001301"
     CDS             29802..30905
                     /locus_tag="VXE45_001301"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0789329.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            30924..32939
                     /gene="recG"
                     /locus_tag="VXE45_001302"
     CDS             30924..32939
                     /gene="recG"
                     /locus_tag="VXE45_001302"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0789330.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
BASE COUNT         9703 a         6297 c         7424 g         9650 t
ORIGIN      
        1 taaaagcaga tggataatca aaatgagtaa tcaatctttg tcatgatttc atggcaaaga
       61 ttttttttga gtccagattt gtgatagaat agagggagtt gataaaagga ggaaagcatg
      121 gaagaatcaa aagaattaaa tgccgtcatt gatgtgatta tgctagcggg gactattctc
      181 cttaaaagtg gctcagaaat ccatcgtgta gaagatacca tgattcgaat cgcgcattcg
      241 caggggattg tggattgcaa tgtccttgcc atgcctgccg ctatcttttt ctctattgaa
      301 aataccaata tttcgcgcat gaagcgcgtg acctcctctt cttataacat cgaaaaagtc
      361 tgcgatgtga accagatttc tcgtcagcta gttggggggc agattgactt agaaacagcc
      421 tttaagcaat tgacggcctt gcaagctcaa ccccttccct atactaagtt gcaggtaact
      481 ctggctgcga cctttagtgc tcctttcttt tcagttatgt ttagcggaaa tatctacgac
      541 gcacttggtg caggagtggc gaccttattt ggttttgcct tttccctcta tgtggaaaaa
      601 tttatccgaa ttccctttgt gacagccttt gctggagcct ttgtctttgg gataattgcc
      661 cagttttggg ctcgctacac aggttttcct tcaacggcag atttgattat agctggtgcg
      721 gtcatgccgt ttgtaccagg tattgccttg accaatgcgg tccgtgatat tatgaccaac
      781 cacataaact ctggtatgag taagatgttt gaatccctgc tcattaccct cgctttaggg
      841 gcaggaactt ctgtcgcctt ggtattgatg aactaatatg acactaacaa cctttttatt
      901 acaagcagta gcaagttttc ttgccattat cactttttta atcgtactca atgtgcaacg
      961 gtctatgctc ttacctggag ggattttggg catgactgtc tggctaatct atctcttgct
     1021 caaggaaccg accaatgtca ttgtagctac cttcattgca gccattattg gttcttgtgt
     1081 cagccagatt ttaagtattc tttataagac acctgctgtg gtctttatct tggccatttt
     1141 ggcaccgctg gttccaggtt atctctccta ccgaacaact gccttttttg tgacagggga
     1201 ctataataaa gcactggcaa gtgcgacctt ggttgtcatg ttggctttgg taatctctat
     1261 tggaatggct agcggaacag tgattctcag actgtatcat tatataaaaa cacatcgagt
     1321 atcgtagact ttacagaaat aaaagaattt tctgaaaaat gagataaata aattaacaac
     1381 gctttctata tgtgcgagaa taccgcactt atgaagaaat tgcgactgat tttggtatcc
     1441 acgaaagcaa cttactccgt cggagccaat gggttgaagt aactcttgtt caaaggtggt
     1501 gttacgattt caagaactcc tctcagttct gaagacacgg taatgattga tgcgacggaa
     1561 gtaaaaatca atcgccctaa aaaaaacaat tagcgaatga ttctggtaaa aagaaatttc
     1621 acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatca
     1681 ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag
     1741 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     1801 aaactccacg taaatccagc aaactcaagc tgctaacagt tgaagataaa gcctataacc
     1861 atgcgctatc taaggagaga agcaaggttg agaacatctt tgccaaagta aaaacgttta
     1921 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     1981 ttgctggcat tatcaatcat gaactaggat tctagttttg caggaagtct actactttcc
     2041 ttattgtctg taaatctact gaccttgttg tttatcccag tcatggtttc tagttcgggc
     2101 tcagagtttc aaagtggatg gcaagagcat caattgattg ctgagaaggt tagtaaaaca
     2161 cttgataaga catttgataa ggatgtcaga gaaattccga ccagtcagtt ttatcaaaaa
     2221 tttgtagatg agatgggaag gacttactca ggaaatttga tcctccagga gctgataact
     2281 gtgaatggag cttataaagc tacttatatc ggtgaactct ctagcaacta atcattcttt
     2341 aaaatgatga ccaataagag gcttgatttg gtgaatcaag tcttttttct ctcttttact
     2401 gccatttgtg ataaaatagt atagaacgat tttttacatg aatgataaaa cagaggtaaa
     2461 tatgacaatc ggtattgata agattggttt tgcgaccagt caatatgtct tgaaattaca
     2521 agacttagca gaagcgaggg gaattgaccc tgaaaaatta agtaaaggac tcttactcaa
     2581 ggaattgagt attgcgcccc taactgagga catcgtgacc ttggcggcca gtgctagtga
     2641 ctctatttta actgagcaag aaagacaaga agttgacatg gtcattgtgg cgaccgagtc
     2701 aggaattgac cagagtaagg ctgcggccgt ctttgtgcat ggcttgctgg gcatccagcc
     2761 ctttgctcgt agtttcgaga ttaaagaagc ctgctatggg gcgactgctg ccctccatta
     2821 tgccaaattg catgtggaaa attctccgga gtccaaggtc ttggtcattg caagtgatat
     2881 tgccaaatac ggtattgaaa ctccgggaga acccactcag ggtgccggaa gtgtggctat
     2941 gttgattaca caaaatccac gcatgatggc ctttaataat gacaatgtag ctcagacccg
     3001 tgacatcatg gatttctggc gaccaaatta ctcgacaact ccttatgtaa atggtgtcta
     3061 ttctacccaa caatacttgg atagtttgaa aacgacttgg cttgaatatc aaaaacgcta
     3121 ccagcttact ttggatgatt ttgcggctgt ttgtttccac ttgccttatc ctaaattagc
     3181 gctaaaaggc ttgaaaaaaa tcatggataa gagcctgcct caagagaaaa aagacctctt
     3241 acaaaagcat tttgaccagt ctattctcta cagtcaaaag gtggggaata tctacacagg
     3301 ttcacttttc cttggacttt tgtctctctt ggaaaataca gatagcttga aagctgggga
     3361 taaaatcgcc ctttatagtt acggaagtgg agctgtggct gagttcttca gtggtgaatt
     3421 ggttgaagga tatgaagctt atttggataa agaccgcttg aacaagctca accaacgaac
     3481 tgtcttatcc gttgcagact atgaaaaggt cttttttgag gaagtaaact tggatgaaac
     3541 aaactctgcc cagtttgctg gctatgaaaa tcaagatttt gccttggttg aaattctcga
     3601 ccaccaacgc cgttatagca aggttgaaaa ataatgaaga taagttggaa tgggttttct
     3661 aaaaaatcat accaagagcg cctcgagctg ttaaaagctc aggcgctcct tagtcctgag
     3721 agacaagcta gtctggagaa ggatgaacag atgagtgtga ctgtggcaga ccagctgagt
     3781 gagaatgtag tgggaacttt ttctctgcct tattcgctgg ttccggaggt acttgtcaac
     3841 ggtcaggaat acaccgttcc ctatgtgaca gaagaaccct ctgtggttgc ggcggccagc
     3901 tatgccagca aaatcatcaa gcgtgcaggt ggttttactg cacaagtcca tcagcgccag
     3961 atgattgggc aggtagccct ttatcaagtt gctaatccta aactagcgca agagaagatt
     4021 gccagcaaga aagcggagct cttggagctt gccaatcaag cctatccttc tatcgttaaa
     4081 cgtgggggtg gggcgcgtga cctgcatgtc gagcagataa aaggcgaacc agactttctc
     4141 gttgtttata ttcatgtcga tacccaggaa gccatgggtg ccaatatgct caacaccatg
     4201 ctggaagcct tgaaaccagt cttagaagaa ctcagtcagg gacagagtct catgggaatc
     4261 ctgtccaact acgcgaccga ttctctggtg actgcaagct gtcgcatggc ctttcgctac
     4321 ttgagccgcc aaaaggatca aggacgagag attgcggaga aaattgcgtt ggctagtcag
     4381 tttgcgcagg atgatcctta ccgagctgct actcataata aaggaatttt taatggtatt
     4441 gatgcgattt tgattgccac tggtaatgac tggcgtgcca tcgaagctgg ggcccatgcc
     4501 tttgccagtc gagatggacg ctatcaaggt cttagttgct ggacgctgga ccttgaaaga
     4561 gaagaattgg tcggtgagat gaccctgccc atgcctgtag cgactaaggg tggctctatc
     4621 ggcctcaacc cacgtgtagc tctcagtcat gatctactag gaaatccttc tgccagagaa
     4681 ttagcccaga ttatcgtgtc tatcggtctt gcccaaaatt ttgcagccct caaagccttg
     4741 gtaagtacgg gcatccagca aggccacatg aaactacagg ccaaatccct agctctccta
     4801 gctggggcta gtgaatctga agttgctccc ctagtcgagc agcttatcgc agataaaacc
     4861 tttaacctag agacagccca gcgctatctc gaaaatttaa gatcataaaa aactcagacg
     4921 aatcggtctg agttttcttg tgtttaaata ctttttcctg gtaatagtgt aactggtaag
     4981 aagtaaccag ttgtggtgac ttccttgcct tcaatctttt gcaagagaag atcaatagtg
     5041 agacaagcaa tctcttccaa aggttgcttg atagtagcca attgagggta gtaattttcg
     5101 ataaagtagg tcccatcata gccgatgacc ttgagctctt ttgggacaga aatgcccaat
     5161 tcttgagcga ttttaatgac cagaatagct gtcaaatcat ccgaagcaaa aatggcatct
     5221 ggtttttccc gggtcaagat attcttgatt tccatttctt ttctgacggg agaaaagtca
     5281 ctggaaacat tgataatagg agcttttggg agtacggatg caaaaccagc gtggcgcagt
     5341 ccggttggcg aattggaatt gtcattccct gtaatcatga tgatagactg ggcacctgtc
     5401 ttgaccaagg tttgggcagc aagaacccca ccagcatagt tgtcagagga gacgacaggg
     5461 atgtctggcg ataggtttcg gtcaaaggaa ataatcggcg ctgtcacacg attgtagtct
     5521 tcgattccta ggttgtgact accagaaatg atgccgtcca cctgattggc ttccaacatt
     5581 tcgatgtatt cacgttcctt ctcagaatca tgttcactgt tgcagatgat ggtcttgtaa
     5641 ccatttttga agagttggtg ttccaattta tcaatcaatt ctgcatagaa aacattggaa
     5701 atattgggga aaatcaagcc gattaactta gctgattttc cttgcagact acgagccagg
     5761 ttgttgggtt tatagcccaa ttctcgcatg gcttcattga ctttttggat ggttttctca
     5821 gatagatacc cttttttatt gataacccga gaaacggtag taggactgac gcctgcaagt
     5881 ttggcgacat cagttagttt tgcgaccata atctaattca tagtaagttc cagttgggtt
     5941 tccagatttg atcaggatac cattttggtc cgcatgtggg aagacacgac cagaaaatac
     6001 tttttctcct ttattgatga aaatttcaaa gacagagtta tcgatgaaga ttgtagcagt
     6061 agtagcctga ttctcgatag ggcaagaacg agttgtccca aattcttggg catactgttc
     6121 tccagcctgg ctacgatcca ctgtcacttg accgtttaca aggtcaaagt tgattgaaag
     6181 tcccttacct tctttatcag caagtaagac aatctcgctc tggctattag cttccaagtt
     6241 gagttcaagt tcgtaagtgt tcttggtttg ggaacggttt gagaaggctt cttcagaagc
     6301 acgaaggtcc ttaatagcag cgactggata ctggtagagc ttgtcgtctt tgatagtgag
     6361 ttccttgacc aaagagaagg ttccttggtg gtcaaaacgg tcagatgggt aagaaacatc
     6421 tggcaaacca agccagctaa ctgctagagc acgcccatca ggagcgttga aggcttgagt
     6481 tgcataggct tcgaaaccgt aatccatgtt ttgaagttga gacacatcta ccattttggc
     6541 atttttaggg tcaaaggaag ccccaatctt atacatattt ggaaagatat tatcgtagtc
     6601 tagaactttc ttatccaatc cttgtggaca gtagagaagg acaggttgtt cctctacaaa
     6661 gaccagatta ggacattcca tcatgtaggc agtacggtcg ttagcaaagt caaggtcgcc
     6721 aactgcttgc cagtttgtgt agtcgttatt gacagccttg tagagacgaa cgaaaccttt
     6781 tttctccaag tcctgtccac cgacgacagc atagtattga cctttaaagt taaaaatttg
     6841 tggatcgcgg aagtggtcag tagagtctgc tggctggtca atcaagatct tgtcaatctt
     6901 tgtaatctta ccctccttgt ccatcaaagc accgatctgg tatgggtgac ggatccagtt
     6961 ttcatcgcga acatttcctg tataaaatag gaataagtta tcgccaaatt gcatggcaga
     7021 accagagtag gcaccgtggc tatctaatgg agtatctggt aaaactttga ttccagtttc
     7081 tttaaagtga accaaatcat cactttctag ctgtgcccaa gattttaaac cgtgggctgc
     7141 accaaaagga aaattctggt aaaagaggat ccacttgcca tcaaagtaag aaaagccatt
     7201 tgggtcgttg agaagtcctg tttttggctc aacatggtaa tgagtatgcc atggagattg
     7261 tgccatattt tcctttatat gttgaatttc ttcttgcgtc caatcttgat aaagtctgta
     7321 acgacgctca gttgtccatt ccattcattc ctccaaaaat cttatcactt ttaatagtaa
     7381 ctgttttcga taaaaaatgc aagcctttta tgttaaaaaa gaggaaaaac tgtcaaagga
     7441 ttatcataaa ataaatacag gaaatcaatc aaatttttac gaaaatgtga aagataatga
     7501 aataaaagac tttttaacca aggtttcaaa cttatttttc aaggaattcc tgatgaaaca
     7561 gtcaaaaaca atcaatctaa agcttgccca ctaagtggat agaatatttt tctgcaaaac
     7621 gcttgacata tttttaaaac atgataaaat aatagtcgta agggcgaata aaatcgcttt
     7681 caaacaagaa caaaatgtta tataaggaga tttttgcaaa tgaacaatca ggaaattgca
     7741 aaaaaagtca tcgatgcctt gggcggacgt gaaaatgtca atagtgttgc ccactgtgcg
     7801 actcgtctac gtgtcatggt caaagatgaa gagaaaatca ataaagaagt gattgagaac
     7861 ttggaaaaag ttcaaggtgc tttctttaac tcagggcaat accaaattat ctttggtaca
     7921 ggtacagtta acaaaatgta cgatgaagtt gttgtacttg gcttaccaac atcatctaag
     7981 gatgacatga aagcagaagt tgctaaacaa gggaactggt tccaacgtgc tatccgtact
     8041 tttggtgatg ttttcgttcc aatcatccca gttatcgtag cgacaggtct cttcatgggt
     8101 gtgcgtggtc ttttcaacgc tcttgaaatg ccacttccag gtgactttgc aacttacaca
     8161 caaatcttga cagatacagc cttcatcatc ttgccaggtt tggttgtgtg gtcaaccttc
     8221 cgtgtatttg gtggaaatcc tgccgttggt atcgttcttg gtatgatgct tgtctctggc
     8281 tcacttccaa acgcttgggc agttgctcaa ggtggtgaag taacagcgat gaacttcttt
     8341 ggtttcatcc ctgttgttgg tttgcaaggt tccgttcttc cagccttcat catcggggtt
     8401 gtcggagcta aatttgaaaa agctgtccgc aaggttgttc cagatgtcat tgacctcttg
     8461 gtaacaccat tcgtgacact tttggtcatg tctatccttg gactctttat cattggacca
     8521 gttttccacg ttgttgaaaa ctacatcctt attgctacaa aagcgattct tagcatgcca
     8581 tttggccttg gtggtttctt gattggtggg gttcaccaat tgatcgtcgt gtcaggtgtg
     8641 caccacatct tcaacttgct tgaagtgcaa ttacttgctg ctgaccatgc taacccattc
     8701 aacgctatca tcacagctgc tatgacagct caaggtgctg ctactgttgc ggttggtgtt
     8761 aaaacaaaaa atccaaaact gaaaacactt gctttcccgg ctgctctttc tgccttccta
     8821 ggtattacag agcctgctat cttcggggtg aacttgcgct tccgtaaacc attcttcctt
     8881 tcattgattg ctggtgcaat cggtggtgga ttggcttcta tccttggact tgctggtact
     8941 ggtaatggta tcaccatcat ccctggtaca atgctttatg ttggtaacgg acaacttcca
     9001 caataccttc ttatggtagc tgtatcattt gcccttggtt ttgctcttac ttacatgttt
     9061 ggttacgaag atgaagtaga cgcaactgca gctgcaaaac aagctgaagt ggctgaagaa
     9121 aaagaagaag ttgcgccagc agctcttcaa aatgaaacac ttgtaactcc tatcgtcggt
     9181 gatgttgtcg ctcttgctga tgtcaatgac ccagtcttct caagtggagc tatgggacaa
     9241 ggtatcgctg tgaaaccaag ccaaggcgtg gtctatgcac cagctgatgc tgaagtttca
     9301 attgcctttc caacagggca cgcttttggt ttgaaaacaa gaaatggtgc tgaagttttg
     9361 attcatgttg gtattgatac tgtatctatg aacggtgacg gttttgaaac aaaagttgct
     9421 caaggtgata aggtgaaagt tggcgatgtt cttggaacat ttgactcaaa caaaatcgct
     9481 gcagctggac ttgatgatac aacaatggtt atcgttacaa atacaggtga ctacgcttca
     9541 gtagctccag tcgcaacagg ttcagttgct aagggggatg ctgtgatcga agtgaaaatc
     9601 taatcaatcc tctctaatgt gaaaacgaac aaatgacata tttgttcgtt tttattagat
     9661 agtaagattt acagaggaaa atctaaaaaa tagagacatt tagactttcg aagtatgcta
     9721 taataaagaa aataaaaaca agaggtttat catgacaaaa ttatatggaa gcttggaagc
     9781 gggcggtaca aagtttgtct gtgctgtcgg tgatgaaaac tttaacgttg tagaaaaaac
     9841 acaatttcca acaacaactc caatcgaaac aatcgataaa accattgagt tcttctcaaa
     9901 attcgataac cttgctggtc ttgcagttgg ttcatttggg ccgattgata ttgacaaaaa
     9961 ctcaaaaact tatggcttta tcacgacgac tccaaaacca aactgggcaa atgtggactt
    10021 gcttggtgcc cttcgtcgcg ccctaaatgt gccaatgtac ttcacaacag acgtaaacag
    10081 ctctgcttac ggtgaagtgg ttgcccgtaa caatgctggt ggtcgtatcg aaaacttggt
    10141 ttactacaca atcggtacag gtatcggtgc aggtgtcatc caacgtggtg agtttatcgg
    10201 tggtgtgggt caccctgaaa tgggtcatta ttatgttgct agacacccaa tggatattga
    10261 aaaagagttt aagggtgttt gtcctttcca taagggatgt ctagaaggtt atgcagctgg
    10321 tccaagtttg gaagctcgta caggtgtacg tggggaaact attgaactca acaaccctgt
    10381 ttgggatgtt caagcctact atatcgctca agctgcggtt aatgcgacag tgactttccg
    10441 cccagacgtg attgtctttg gtggaggggt catggctcaa caacatatgc tggaccgtgt
    10501 ccgtgagaaa tttacatctc ttcttaatgg ttacctacca gtaccagatg tgcgtgacta
    10561 tatcgtgacg ccagcagtcg caggaaatgg ttctgccaca cttgggaact ttgttcttgc
    10621 aaaagaagtt tcaaaataaa gcacaaaatc cgcttgggaa accaaacgga ttttttacgt
    10681 gtcaaagcat ttgccagaaa aagtcaataa tataggtcag accgtaggta taaaccacga
    10741 gggtaaaggg tttggtcaga atgatgatgg tcatgtagcg cttgaaactc atcttggtca
    10801 gggcagccag catacagaga aagtcagctg ggctaatggg ccaaatcatc ataaaaataa
    10861 agaagcggtc aaaacgattg cccttatcta gccagccgat gtacttgtcg taggtgcgct
    10921 tgctgacgac agactggaca aaggcagctc cgtataggcg cactagataa aagataatgg
    10981 cacagccaat cacgatgccg atatagttgt agatagtccc gatgatgtgc ccgtagataa
    11041 agaccccagc caccgaggtc aaggcccctg gaatgatagg gacgacagtc tgtaaaatct
    11101 gtaaaaagat aaagagaggt ggaccccaga tgcctgcctg ctggataaag gcagagaggg
    11161 tttccttgga ttgtaaaatc ccagcctgat aagcccaaat acagaaaatc aaactcccaa
    11221 ccccaccgac aatcgatgag atattgataa ctcgctgcag aaggggagaa acagctttca
    11281 tttgtttatc ctgtgacatg taaactcctc atagatagta tatttctact ataccatatt
    11341 ttggaggaga aagggggaat gagtcttttt tgataaggaa tagaaagtaa atagcccttc
    11401 gagacttaga ataggtctgt caactaaagg ttatatgcat tctaggtttc gaataatcgc
    11461 aattccataa atttaaaagt attctaagtt tcgaatagct tatctgggat aattttgagg
    11521 cattcgcgct ttcgaatagt cattttccct aaagtttata tgtattctga agctagaaag
    11581 actaaaatat aaaagtagta agagtctctc tctgatggac gtaatttatg gctagtatga
    11641 atcctttgaa ttgttagtta attttaatat taatcagttc tgaaataatt actaaatata
    11701 gttagatggt gagttaatta ttgctaaatt tcaagttcaa gttagtcatc cagaagtctt
    11761 ctctggggga cttgtagttc aagcattttt taggatagtt gttaatccac ttttcgataa
    11821 atgcgacttc ctttgtagtt gttttcttag ttccctgagg taaccatcta tgaatgagcc
    11881 tgttgtgatt ttcattagat cctatagtga tgtgcataat agatatagca gattgaaact
    11941 agaatagtat acatctactt ctaaaacatt gttagaaatc aatttgactg tcctgatcaa
    12001 tttgtcctgt ttttatttca ttttactata taatccttag aaaacatatc ggacaagcgg
    12061 ttgaattccg ttccgtccat tagtagataa aggattactc cttcttgaaa tgacagatga
    12121 acttgtttct tataaaaatg ttgtctgaaa ctattagcct ttttccagaa gttttagagg
    12181 aagaaaactt tacgaggaaa aaggagttac tcaaataaca attcaggatt aaaaatagac
    12241 agttgaggag cggaaggtat aaattaagtt tgctactgta taatggattt atcactaata
    12301 ctcttcgaaa atctcttcaa accacgtcag cttcgccttg ccgtagatat agttactgac
    12361 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttttatc
    12421 tgcaacctca aagctgtact ttgagcagcc tacggctagc ttcctagttt gctctttgct
    12481 tttcattgag tataaaagtg ctccaggcca tattttacac agcaatagtc ttctaaaaat
    12541 ggacaaaaac attgtaaagg ctatcaaaaa ggagtataat gagtgcaaga aatttcggag
    12601 gtgaaagatg ctagaagtaa gaagtctaga gaaaagtttt ggctccaagc aagttttgtt
    12661 tggtattgac tttcaagcgc gaccaggtcg tattttggga ctagtcggaa aaaatggtgc
    12721 tggaaaaaca acgattttcc atagtatttt gaaattccta gaatatcagg gagaaatcgg
    12781 tctggatggt caggatattc gtcaggagac ctatgctcgg attggttatc tgcctgaaga
    12841 acgcagtctc atgcctaaat tgacagttct tgaacaagtt cgctacttgg cgactctaaa
    12901 aggcatggat gccaaagaag tcaaagaaaa actccctcaa tggatgaaga ggttggaagt
    12961 gaaaggaaag ctgacagata aaatcaagag tctgtcaaaa ggaaatcagc agaagattca
    13021 gctcattatt actctgattc atgaaccaga cctgattatc ttggatgagc cttttagtgg
    13081 attggaccca gttaatacag aattgctcaa acaagtcatt tttcaggaaa aagagcgcgg
    13141 agcaaccatt atcttttctg accatgtcat gaccaatgtt gaggaacttt gtgacgatat
    13201 tctgatgatc cgagatggcc gtgtggtctt gcacggacca gttcaggatg tccgcaatca
    13261 atacgggaaa acgcgtctct ttgtttcaag tgaacgaagc aaggaagaat tggaaaatct
    13321 tcctcatgtc aaacaggtga gcttgaccaa acaaggcagt tggaaattga ttttggagga
    13381 tgagagcgct ggaagggaac tcttcccaat cttgactcaa ggtcaatata tcgcaacatt
    13441 tgaccaacaa gcgccaacta tcgatgaaat ctttaaacta gaatcaggag tggaagtatg
    13501 agaaatatgt gggttgtaat caaggaaacc tatcttcgac atgtcgagtc atggagtttc
    13561 ttctttatgg tgatttcgcc gttcctcttt ttaggaatct ctgtaggaat tgggcatctc
    13621 caaggttctt ctatggctaa aaataataaa gtggcagtag tgacaacagt gccatctgta
    13681 gcagaaggac tgaagaatgt aaatggtgtt aacttcgact ataaagacga agcaagtgcc
    13741 aaagaagcaa ttaaagaaga aaaattaaaa ggttatttga ccattgatca agaagatagt
    13801 gttctaaagg cagtttatca tggcgaaaca tcgcttgaaa atggaattaa atttgaggtt
    13861 acaggtacac tcaatgaact gcaaaatcag cttaatcgtt caactgcttc cttgtctcaa
    13921 gagcaggaaa aacgcttaga gcagacaatt caattcacag aaaagattga tgaagccaag
    13981 gaaaataaaa agtttattca aacaattgca gcaggtgcct taggattctt tctttatatg
    14041 attctgatta cctatgcggg tgtaacagct caggaagttg ccagtgaaaa aggcaccaaa
    14101 attatggaag tcgttttttc tagcataagg gcaagtcact atttctatgc gcggatgatg
    14161 gctctgtttc tagtgatttt aacgcatatt gggatctatg ttgtaggtgg tctggctgcc
    14221 gttttgctct ttaaagattt gccattcttg gctcagtctg gtattttgga tcacttggga
    14281 gatgctatct cactgaatac cttgctcttt attttgatca gtcttttcat gtacgtagtc
    14341 ttggcagcat tcctaggatc tatggtttct cgtcctgagg actcagggaa agccttgtcg
    14401 cctttgatga ttttgattat gggtggtttt tttggagtga cagctctagg tgcagctggt
    14461 gacaatctcc tcttgaagat tggttcttat attcccttta tttcgacctt ctttatgccg
    14521 tttcgaacga ttaatggcta tgcgggggga gcagaagcat ggatttcact tgctattaca
    14581 gtgatttttg cggtggtagc aacaggattt atcggacgca tgtatgctag tctcgttctt
    14641 caaacggatg atttagggat ttggaaaacc tttaaacgtg ccttatctta taaatagaag
    14701 agccttgcga aagcgaggtt tttaaagatg aaaaggatgg aatcacgaac ctaattatgt
    14761 acacattatg taaacaggtt gcttgaaaac tcaattgtat agtgaactga atctggaata
    14821 ggataatatt acttctaaaa cattcttata aattgatttg aattccaaaa tcccatcgtt
    14881 ccgttcttat ttcattttgc gatatagtga aaggaaataa gtcagctcac aaaaaacgca
    14941 taatatcaag gatttttaac acttgatact atgcgttttc taattttaaa gactttttgc
    15001 ctggtctctt ttgttctatg agtatgttac atatctaggt aaaaattatt taaagcaaat
    15061 taaccttatt tctcaagatg tagtaggttc cgagataaaa gatagctatg aatatgagtt
    15121 ctttaacaat ggctatacct gctcccatat agaaatggtc attgagtcct accagtgaat
    15181 tgacatagaa attagaacta agattgaaga aaagttcaat aaatccaatg acgatttgga
    15241 taccaatgta ggctgcaaca gcgagtgctg tacggtattc attgaaaagc tgtccaatgg
    15301 aaatagccag gtagatgcag aggattcctg aaatggtatt tagtaggaag gatatacctg
    15361 taagaaagat ctgagggaga tgtgtttcta caaatgtaat cacataagaa agaggaatcc
    15421 attctggagc tgttaaagcc agaataataa cagcacttag agccaataca gcggtgctaa
    15481 tcaatgacca gataaaggca ccgattagtt tggctgtgat gatatggtgt tcagaaactg
    15541 gcaaggtcaa agtcagatag ccttgtcggt cgtagacact acctttgaag cgtttaataa
    15601 tcaagaaaat ggttgaaatc gcaagtgtaa gcatcaagcc accaaagact gtagctagaa
    15661 aaagtagcat agtagcctga ctttcttggt aaggtagatt tttaaagcct tgtgtctgta
    15721 ttccgatgag ggcagaaagg actagcacgg ctgcgtagag ggctaaatac cacttgttaa
    15781 catttttaaa ttcgtagtga actaaattcc aaaacataaa taatctcctt tgcttaggcc
    15841 ttaaattcct gacggaagag ttggtcaatg gattcacctg actcgtagcg aatatcatct
    15901 acatttcctt gacggacgac ttttccgtct tttaggaaga caatttcatc caagattggc
    15961 tcgatatcag aaatcaagtg ggtagaaatc aaaacggtag aagttggtga gtagttgttg
    16021 ataatggtat tgaggatata agcacgggct gctggatcca ccccaccaat gggttcatcc
    16081 aaaacataga gacgagcatc acggctcata accaaaatca gttgaacctt ttctttgttt
    16141 ccttttgata gtttcttgag acgactattt tcatcaatgc ccaggtctgc aagtagatga
    16201 tgagcgcgtt caagattgaa atctttatag aaggtcttga agtaggttag ggcttctttg
    16261 accttcattt gctcattgag ataggtcgta tcaggcaaat aagctacaac ggccttggtt
    16321 gctgggcttg ggtccatgtc gttgatgagg acacgtcctt gatctggttg taagaggcca
    16381 ttaattagtt taatcagggt tgtttttcct gagccgtttg gcccaagaag gccgacaatt
    16441 tttccagctg gaatgtcaag agaaacattt tcaagggctg gtgttgctcc atatgatttg
    16501 gatacatttt caaatactag taatgacata ggcttaaact cctttaatat aatcactgac
    16561 tacgcctggt agttcttctt tttcatagcc aaaatggatc atggaggaaa cgaagtgttc
    16621 caattcttct tctgataatt gtttgcgtga ctgagcgatt agctccttat ccttagtcac
    16681 aaatcgtcca gttgttcgct tgctgtagac aaatccttct cgttcaaggt ctgataaggc
    16741 tctttggatg gtattgggat tgacaccagc ctcgctagct agctccctca cggttggaag
    16801 ttgttgattg ggttccagtg tatgggaaac aatctgaagc ttgattttct ccataatctg
    16861 taaatagatg ggttttttgt tgtcaaatgt ccaggacatc ttagtctcct ttctcttatc
    16921 cttttgtctt aactaaataa tacaacaaaa caaaaaactt gtcaagcaaa aagaagaatt
    16981 gttttgggaa tcgcttaaaa aatggtataa tgaaaagaaa acgataagga gggaaaggat
    17041 gcgttgtcca aaatgtgggg ctaccaagtc aagtgttatc gatagtcgcc aagcagaaga
    17101 agggaacacc attcgtagaa gacgtgagtg cgacgaatgc caacaccgtt ttacaaccta
    17161 cgaacgagta gaagaaagaa ccttagtggt tgttaaaaaa gatggtacac gggaacaatt
    17221 ctccagagat aaaatcttta atgggattat ccgctcagcc cagaaacgtc ctgtgtcaag
    17281 tgatgaaatc aacatggtag tcaatcgtat cgaacagaaa ctccgtggtc gaaatgaaaa
    17341 tgaaattcaa agtgaggaca ttggttcact cgtcatggag gagttggctg aattggacga
    17401 gattacctat gtacgttttg ctagtgtcta tcgtagtttt aaggatgtca gtgagttaga
    17461 gagcttgctc caacaaatca cccagtcctc taaaaagaaa aaggaaagat aaatgaagcc
    17521 aattgaccgt ttttcttatc taaagaataa tcgggtgtcg caagatacct catctctggt
    17581 acagtgctac ctcccgatta tcggtcagga ggcactgagc ctttatcttt atacaatcag
    17641 tttttgggat aatggtagaa aggaatatct tttttcaagt atcctcaatc atctcaactt
    17701 tgggatggat agactgataa aatcattgaa aatcttatct gcttttaatc tcttgaccct
    17761 ctatcaaaag ggggatgttt atcagctagc cctccatgct cctctatcta gtcaagactt
    17821 cttggagcat cctgtttatc gcagactctt agagaaaaag attggcgact ctgctgtgga
    17881 ggatttgaaa gttgaaagtg ctgatggtga agaaatacct gtctcactca atcaagtctt
    17941 tccagaattg gcagaactag gcagtcaaga agaccttggt ctcaagaaga aagtggccaa
    18001 tgattttgac ttggaacatt ttcgccagct gatggctcga gatggacttc gttttgcgga
    18061 tgagcagtcc gatgtcttaa acctctttgc tattgccgag gagaagaaat ggacttggtt
    18121 tgaaacctat caattggcca agtcaacagc tgtttctcag gttatttcaa ccaaacgcat
    18181 gcgtgaaaaa attgctcaaa aaccagtttc ctctgacttt aatcctaagg aagcaaccat
    18241 tatcaaggaa gctaaaagta agactgccct gcagttctta gcagaaatca agcaaacacg
    18301 caaggggacc attacccaaa cagaaagaga acttttgcaa cagatggctg gcttgggctt
    18361 gctggacgaa gtcatcaata tcattctctt gttgaccttt aataaggtgg attcggcaaa
    18421 catcaatgag aaatatgcca tgaaggtggc taatgactat gcctatcaaa agatacattc
    18481 agcagaagag gccgttttac gaattcgtga gcgagggcag aaaacaaaaa cacaaaaaca
    18541 gaatcagact gccccagcaa aaaccaatat tcctaaatgg agtaacccag attataagaa
    18601 tgaaaccagc gaggaaactc gtctggaact agaacgtaag aaacaagaac tattagctcg
    18661 attagaaaaa ggaggagatt agatggaaag tgtcggagac gtactcaaac gtcaacccag
    18721 ccgtttttat tatcaagatt tggtccagaa aatcatgaag gaccctgatg ttgcggcttt
    18781 tatccagcaa gaatccttga ctccagagga attaaatcgc agtatctcca agtttaatca
    18841 gtacatcacc gagcgtgaca agtttctccg tggggatacg gattatattg ccaaaggcta
    18901 caagccgatt ttggttaaga atcatggcta tgcagatgtt tcatatgaag aaactcctga
    18961 gctaatcgcg gctgaaaaag aagcggctat taagaatcgt ctcaagctaa tcaatctacc
    19021 agccagtctc aaaaaagcta gtttggctca agttgatttg gatgatttgg gacgcttgcc
    19081 agtttttgaa aaactattag cctttgtgga gcaatatcca gctattcgaa aaggtcttta
    19141 cttatatgga gactttggtg tgggtaaaag tttcatggtg gcggccttag ctcatgattt
    19201 atcagaaaaa cgtggtgttt catcaactct cctccactat cctagctttg tcattgatgt
    19261 caaaaatgct atcagtgatg gcaatgttaa gaccttggtg gatgagatta agctgtctga
    19321 ggtcctgatt ttagatgata ttggcgccga gcaatcaacc gcttgggtgc gtgacgaaat
    19381 cctgcaggtc attctccaat atcggatgca ggaaaattta ccgacctttt tcacatccaa
    19441 cttcaacttt gaagatttgg agaagcattt tgcgaaagtg aaacatggaa atgacgaaac
    19501 ctgggaagcc agacgggtca tggaacgcat ccgttatttg gctgaggaga ctcgtttaga
    19561 aggagtaaac cgtcgatgac agaaaccatt aaattgatga aggctcatac ttcagtgcgc
    19621 aggtttaaag agcaagaaat tccccaagta gacttaaatg agattttgac agcagccaag
    19681 atggcatcat cttggaagaa tttccaatcc tactctgtga ttgtggtacg aagtcaagag
    19741 aagaaagatg ccttgtatga attggtacct caagaagcca ttcgccagtc tgctgttttc
    19801 cttctctttg tcggagattt gaaccgagca gaaaagggag cccgacttca taccgacacc
    19861 ttccaacccc aaggtgtgga aggtctcttg attagttcgg tcgatgcagc tcttgctgga
    19921 caaaacgcct tgttggcagc tgaaagcttg ggctatggtg gtgtgattat cggtttggtt
    19981 cgatacaagt ctgaagaagt ggcagagctc tttaacctac ctgactacac ctattctgtc
    20041 tttgggatgg cactgggtgt gccaaatcaa catcatgata tgaaaccgag actgccacta
    20101 gagaatgttg tctttgagga agaataccaa gaacagtcaa ctgaggcaat ccaagcttat
    20161 gaccgtgttc aggctgacta tgctggggcg cgtgcgacca caagctggag tcagcgccta
    20221 gcagaacagt ttggtcaagc tgaaccaagc tcaactagaa aaaatcttga acagaagaaa
    20281 ttattgtaga aagtgagaaa ttatggccct accaactatt gccattgtag gacgtcccaa
    20341 tgttgggaaa tcaaccctat ttaatcggat cgctggtgag cgaatctcca ttgtagaaga
    20401 tgtcgaagga gtgacacgtg accgtattta tgcaacgggt gagtggctca atcgttcttt
    20461 tagcatgatt gatacaggag gaattgatga tgtcgatgct cctttcatgg aacaaatcaa
    20521 gcaccaggca gaaattgcca tggaagaagc agatgttatc gtctttgtcg tgtccggtaa
    20581 ggaaggaatt accgatgcag acgaatacgt agcccgtaag ctttataaga cccacaaacc
    20641 agttatcctc gcagtcaaca aggtggacaa ccctgagatg agaaatgata tctatgattt
    20701 ctatgctctc ggtttgggtg aaccattgcc tatctcatct gtccatggaa tcggtacagg
    20761 ggatgtgcta gatgcgatcg tagaaaatct tccaaatgaa tatgaggaag aaaatccaga
    20821 tgtcattaag tttagcttga ttggtcgtcc taacgttgga aaatcaagct tgatcaatgc
    20881 tatcttggga gaagaccgtg ttattgctag tcctgttgct ggaacaactc gtgatgccat
    20941 tgatacccac tttacagata cagatggtca agagtttacc atgattgata cggctggtat
    21001 gcgtaagtct ggtaaggttt atgaaaatac tgagaaatac tctgttatgc gtgccatgcg
    21061 tgctattgac cgttcagatg tggtcttgat ggtcatcaat gcggaagaag gcattcgtga
    21121 gtacgacaag cgtatcgcag gatttgccca tgaagctggt aaagggatga ttatcgtggt
    21181 caacaagtgg gatacgcttg aaaaagataa ccacactatg aaaaactggg aagaagatat
    21241 ccgtgagcag ttccaatacc tgccttacgc accgattatc tttgtatcag ctttaaccaa
    21301 gcaacgtctc cacaaacttc ctgagatgat taagcaaatc agcgaaagtc aaaatacacg
    21361 tattccatca gctgtcttga acgatgtcat catggatgcc attgccatca acccaacacc
    21421 gacagacaaa ggaaaacgtc tcaagatttt ctatgcgacc caagtggcaa ccaaaccacc
    21481 aacctttgtc atctttgtca atgaagaaga actcatgcac ttttcttacc tgcgtttctt
    21541 ggaaaatcaa atccgcaagg cctttgtttt tgagggaaca ccgattcatc tcatcgcaag
    21601 aaaacgcaaa taaaaaagta gaatctggaa tgacagttcc ggattttttt gatataataa
    21661 aataatagaa aacgctatca aaagaaggag ggtgatgtcg gtgatggaac atttgtttaa
    21721 attcttactt ttagcaccgt acttttattt tgataactgg attgagaagg ccaacagaaa
    21781 tagtaagttt tttccaattt tttattattt ttactggttt tacatcccct tctattctct
    21841 ttttagcctt gcttggacag ttgtttcagt tctgtttttc aataccgtct tgagaaattt
    21901 gacagatatc aagttatggg gtatttggct attattacta cttatcgctt ttgctagtga
    21961 ctggttagac tatatctgtt tcaaaaaaat gcttgacttg agacgggaac tagggaagtc
    22021 taaaggcgga aggcattgat ttatactctt cgaaaatctc ttcaaaccac gtcaacgtcg
    22081 ccttggatta tatatgtaac tgacttcgtc agtcttatct acaacctcaa agcagtgctt
    22141 tgagcaactt gcggctagtt tcctagtttg ctctttgatt ttcattgagt attatattac
    22201 tttctatttg taggaggtgg cttatgaaga ttcctctctt aactttggca aggcataaat
    22261 ttgtttatgt cttgcttact ttgctttttc ttgctttggt ttatcgtgat gttttgatga
    22321 cttatttctt ttttgatatt catgcgcccg atctagctaa attcgatgga caagcaatta
    22381 aaaatgactt attaaaatca gcattagatt ttcgtattct ccagttcaat ctaggttttt
    22441 atcaatcatt tattattcca atcatcattg ttttgctagg ttttcaatat attgagctga
    22501 aaaataaagt tttacgattg agtattggaa gagaagtgag ctatcaaggg ttaaaaagaa
    22561 agttgacttt gcaagttgca agtatccctt gtttgatata tttagtgact gtgctgataa
    22621 ttgcaattat aacctatttc tttgggactt tttctcctct tgaatggaat tctctatttt
    22681 ctgatgggag tggtttacaa agactcctag atggagagat aaaaagctat ttgttcttta
    22741 cttgtgtcct actaatcggt attttcatca atgcaatcta ttttttacaa atagttgatt
    22801 atgtggggaa tgtgactcgt tcggcaatca cctatttgat gtttctttgg cttggttcta
    22861 tgctgctcta tagtgccttg ccttactata tggttcctat gacgagtttg atgcaagcta
    22921 gctatgggga tgtaagtttg atgaaactct ttactcctta tatccttcat gttgtccctt
    22981 atatggtact taaaaaatat gaagataatg tttaagaatt ttaacaatat ttggctaaag
    23041 agaaagatcg ttttactact tcgtatagtt ctgatgatga ttttgataaa ctatctattg
    23101 tcaacagcgg ttcaaaagca ggatgctgtt atctttttca agagagaatt gatttcaatt
    23161 ttttcctata atgactattc tgaagcgaat ttagaaatcc ccaaactctt gttaaacctt
    23221 tcgcttttca tggtaggatg gctctctgtc attttacttg aaagtgattt ggcagaccat
    23281 taccatcact tgattcgcta tcaatcaagc tcctttttcg attatacaag gaaacgattg
    23341 gttgtcattt ctaaattttt tactcaagat ttgtttgtct ggtttcttgg tttacttccg
    23401 ctaggaattc atttcaaaac agtcgcactt ttctttttac ttgctcagtt aatgatgttg
    23461 tacttactac tgtcttatct gatagcactg attagtgcgg gcgctggttt ttcttttttt
    23521 ctctattttt tggcatttgt gggacaagaa tggatgatgg atcatattgt aacagtgtat
    23581 ttagtactct taagcttatt agttatgttg attgttagtc gcttggaaga gaaatttaag
    23641 aaaggataaa cgatgagact tgaaattata aatggacaga aaatttatgg gaaaagacct
    23701 attttaaatc agttgaattt ggtgtttcaa tcaggaaaaa tttatggact taaaggtgat
    23761 aatggatctg gcaagacggt tcttttaaag atacttgctg gttatattaa gcttgacaaa
    23821 ggaaaagttc ttcaagatgg taaagtttac ggggtaaaaa atcattatat tcaggatgca
    23881 ggaattttaa ttgaaaaagt cgagttttta tctcatttat ccctgagaga aaatttggaa
    23941 ctgttaaggt atttttcatc taaagttacg gaaaaaagaa ttgcctattg gattcaatac
    24001 tatgatttac aggaatttga agacgttgaa taccgtcatt tatccttggg aacaaagcaa
    24061 aaaatggcct tgattcaagc ctttatttcc tctccttcta tactctttct cgatgaacct
    24121 atgaatgctt tggatgagaa gagtgtgagg ttaaccaaac aggtcatttt atcttacctg
    24181 aaaaaagaaa atggtctggt tatcctgacg tcgcacatat cggaagatat ttcagacctt
    24241 tgtacagatg tattagttgt cgaaaatgga catatacaat atgtaaagga tatacaatcc
    24301 taggagatgg cttatggcac atctaaaatc atttattaca cgctattcca aggtttatat
    24361 tggtttagtt ctgctgatct ggctgtcttt cttctttatc ccttgggata gagcgattct
    24421 gggggtaagg attgacatct tcatcatgca gaaaatcttg ctagcttttg gaattctgtc
    24481 cattctcatg gccttgctgt ccaagaaagt cagtctcttt gtttttggac tgatttgctg
    24541 tctttctctt tggattaact tatttatcac atttgccatt ttgccgattt ttggcaatta
    24601 aacagtcata aaagtcggag aggttagctt gaaaactaac ctctttttcc ttttcaaaat
    24661 ggggattctt ccttgaaaat aatcagtaat tgtgctaaaa ttaaaggaac attctaaaat
    24721 attcggaatt taaagtaagg aaaaacatgg ctaatatttt aaaaacaatt atcgaaaatg
    24781 ataaaggaga aatccgtcgt ctggaaaaga tggctgacaa ggttttcaaa tacgaagacc
    24841 aaatggctac tttgactgac gaccaactaa aagcaaaaac agttgaattt aaggaacgtt
    24901 atcaaaatgg agaatcactg gattcattgc tttacgaagc atttgcggtt gtccgtgaag
    24961 gtgccaaacg tgtcctaggt ctcttccctt ataaggttca ggtcatgggg gggattgttc
    25021 ttcaccatgg tgacgtgcca gagatgcgta caggggaagg gaaaaccttg actgcgacca
    25081 tgccggtata cctcaatgcc ctttcaggta aaggggttca cgtagttacg gttaatgaat
    25141 acctgtcaga acgtgacgcg actgagatgg gtgaattgta ctcttggctt ggtttgtcag
    25201 tagggattaa cttggctacc aaatctccaa tggagaaaaa agaagcctat gagtgtgata
    25261 ttacttactc aactaactca gaaatcggat ttgactacct tcgtgacaac atggtcgttc
    25321 gcgccgaaaa catggtacaa cgtccgctta actatgcctt ggtcgatgag gttgactcta
    25381 tcttgattga cgaggctcgt acacctttga ttgtatcagg tgccaatgcg gttgaaacca
    25441 gtcagttgta tcacatggca gaccactatg taaaatcttt gaacaaagat gactacatca
    25501 tcgatgtgca gtctaagact attggtttgt ctgattcagg gattgacagg gctgaaagct
    25561 acttcaaact tgaaaacctc tatgacatcg aaaacgtggc tttgactcac tttatcgata
    25621 acgcccttcg tgccaactac atcatgcttc tcgatattga ctatgtggtg agcgaagagc
    25681 aagaaatctt gattgtcgac caatttacag gtcgtaccat ggaaggtcgt cgttattctg
    25741 atggattgca ccaagctatt gaagccaaag aaggtgtgcc aatccaggat gaaaccaaga
    25801 catctgcctc aatcacgtac caaaaccttt tccgtatgta caagaaattg tctggtatga
    25861 cgggtacagg taagactgag gaagaagaat tccgtgaaat ctacaacatt cgtgttattc
    25921 caatcccaac aaaccgtcct gttcaacgta ttgaccactc agaccttctt tatgcaagta
    25981 tcgaatctaa gtttaaagcg gttgtcgaag acgttaaggc tcgttaccaa aagggtcaac
    26041 ctgtcttggt tggtacagtg gcggttgaaa ctagtgacta catttctaag aaattggttg
    26101 cagctggtgt tcctcacgaa gtcttgaatg ccaaaaacca ctatagagaa gcccaaatca
    26161 tcatgaatgc tggtcaacgt ggtgccgtta ccatcgcaac caacatggcg ggtcgtggta
    26221 ccgacatcaa gcttggtgaa ggtgttcgtg aacttggagg actttgtgtt attggtacag
    26281 aacgtcatga aagtcgtcgt atcgataacc agcttcgtgg acgttcaggt cgtcaaggag
    26341 atccaggtga gtcacaattc tacctatctc ttgaagatga tttgatgaaa cgttttggtt
    26401 ctgaacgctt gaagggaatc tttgaacgtt tgaacatgtc tgaagaggcg attgagtctc
    26461 gcatgttgac gcgtcaggtt gaagcagctc agaaacgtgt cgaaggaaat aactacgata
    26521 cccgtaaaca agtccttcaa tacgatgatg tcatgcgtga acaacgtgag attatctatg
    26581 ctcaacgtta cgatgtcatc actgcagatc gtgacttggc acctgaaatt caggctatga
    26641 tcaaacgcac gattgaacgt gtcgttgatg gtcatgcgcg tgccaaacaa gatgaaaaac
    26701 tagaggcaat tttgaacttt gctaagtaca acttgcttcc tgaagattct attacgatgg
    26761 aagacttgtc aggcttgtct gataaggcca tcaaggaaga gcttttccaa cgtgccttga
    26821 aggtttacga tagtcaggtt tcaaaactac gcgatgaaga agcagttaaa gaattccaaa
    26881 aagttttgat tctacgagtg gtggataaca agtggacaga tcatatcgat gcccttgatc
    26941 aattgcgtaa cgcggttgga cttcgtggct atgctcagaa caaccctgtt gttgagtatc
    27001 aggcagaagg tttccgtatg tttaatgata tgattggttc gattgagttt gatgtgacac
    27061 gcttgatgat gaaagcacaa attcatgaac aagaaagacc acaggcagaa cgtcatatca
    27121 gtacaacagc gactcgcaat atcgctgctc accaagcaag tatgccagaa gatttggatt
    27181 tgagccagat tggacgcaat gaactttgcc catgtggttc tggtaagaaa tttaaaaact
    27241 gtcacggtaa aagacaataa aatgagatag tttagaggcg gatatcttgt gaaaagtaaa
    27301 tttttactgg gtatccgttt gctttataag gagatgagtt atggtattta cagcaaaaag
    27361 ctctaaaata aatatagaag aagttcgtgc cttgtcaaaa ttagaaggtc aggctttgga
    27421 gaggaaatca cagcgcgatc aagagctaga agccattata cgtggagaag atcagcgaat
    27481 tctcttggta atcgggccat gctcatctga caacgaagaa gctgtccttg aatacgctaa
    27541 gcgtttggca gtcctacaag aagaagtggc agatcgtatc tttatggtta tgcgtgttta
    27601 tactgccaaa ccccgtacca acggagatgg ctataagggc ttgattcacc agcctaacgc
    27661 gacagaagcg cctagtctta tcaatggaat caaagccgtt cgccatcttc actatcgtgt
    27721 catcacagaa acagggatga caactgctga tgaaatgctt tatcctgaaa accttccgct
    27781 tgtagatgat ttgatttctt acatggcagt tggtgcccgt tcagttgaag accagcaaca
    27841 ccgctttgtg gcaagtgggg caggattttc tactggtttt aaaaatccaa cctctggaaa
    27901 tctcaatgtc atgtttaatg ggatttatgc tgctcaaaac aaacaaagtt tccttttctt
    27961 aggaaaagaa gtagaaacaa ctgggaaccc gctttcacac gctattcttc gtggtgctct
    28021 taatgagtat ggaaaaaata ttcccaacta ctattatgac aatttaattg ataccattgc
    28081 ccaatatgag aaaatgggct tggaaaatcc ttttatcatc attgatacca atcatgacaa
    28141 ttctggtaag cagtatattg aacagatccg aattgtccgc cagaccttga ttaaccgtgc
    28201 ttggaatgaa aaaattaagc agttcgttcg tggttttatg attgagtctt atctggaaga
    28261 tggtcgacaa aatgagccag aagtatttgg caagtctatc acagaccctt gcctgggttg
    28321 ggataacaca gaagctcttg tcagagaaat ttacaaaacg ttaggagaat aagatggcat
    28381 ttattgaaaa aggtcaagaa atcgatatgg aagtcatcaa ggctgaaacc caattgtctg
    28441 cggaagcctt gagactcaag gaaagccgtg acagggaatt ggcagatatt atttcagggg
    28501 aagatgaccg tattctcttg gtgattggtc cttgctcttc tgataatgaa gaggcggtct
    28561 tggaatatgc tcgccgttta tccgccttgc aaaagaaggt agcggacaag attttcatgg
    28621 tcatgcgcgt gtatactgct aagcctcgta ccaatggaga cggctataaa ggattggttc
    28681 accagccaga tacttctaag gctccaagcc tgattaacgg tttgcaggct gtgcgccagt
    28741 tgcattaccg cgtgattaca gagactggtt tgacaacggc agatgagatg ctttatccgt
    28801 caaatctgat cttggtggat gacttggtca gctaccatgc cgttggagct cgttctgtgg
    28861 aagaccaaga gcaccgcttt gtggcttctg ggattgatgc accagtaggg atgaaaaatc
    28921 caacctcagg aaatttgggt gttatgttta acgccatcta tgctgctcaa aacaagcaaa
    28981 ccttccttta tcatgggcag gaagttgaga catcaggtaa tcctttggcc catgttatcc
    29041 tccgtggagc agtcaacgag tatggcaatt atatgccgaa ttactactat gaaaacctac
    29101 tccaagccat tgaacgctat gaaaccatgg gacttgaaaa tccttttatc ctcattgaca
    29161 ccaaccatga taactcaggc aagcaatata tggagcagat tcgaattgtt cgccagacct
    29221 tgcagaatcg tgattggaat gagaaaatta aaaagacggt tcgaggattt atgattgaat
    29281 cttacctagc agatggtcgt caaaaccaac cagagatctt tggttgctct attactgacc
    29341 cttgcctagg ttgggaaaat acagaggcct tggtagaaga gatttatgtt accttgacaa
    29401 aataagtgaa aaggatggag ttggggaatc tcaactcctt ttgatgagaa tgatagttgg
    29461 acacggaatt gacatcgaag aattggcttc gatagaaagc gcagttacac gacatgaagg
    29521 atttgctaag cgtgtactga ccgctcagga aatggagcgc ttcaccagtc tcaaaggacg
    29581 caggcaaata gaatatttag ctggtcgctg gtcggctaag gaggcctttt ccaaggctat
    29641 gggaacgggc attagcaagc tcggttttca ggatttggaa gtattgaaca atgaacgtgg
    29701 ggcgccttat tttagtcagg caccattttc aggaaagatt tggctgtcta tcagccacac
    29761 cgatcagttt gtgacagcca gtgtcatttt ggaggaaaat catgaaagct agtccacata
    29821 gaccaaccaa ggctctgatt catctgggag ctattcgaca aaatattcag caaatggggg
    29881 ctcatatccc tcaaggaacg ctcaagttgg ctgtggttaa ggccaatgct tatggtcatg
    29941 gagctgttgc cgttgccaag gcaattcaag atgatgttga tggcttttgc gtttccaata
    30001 tcgatgaagc cattgaactc agacaagctg gactcagcaa gccaatcctc attttaggag
    30061 tttctgaaat cgaagctgtt gctctagcta aagaatatga cttcaccttg acagtggctg
    30121 gactggagtg gattcaagca ctcttagata aggaagtgga cctaactgga ttgacagtcc
    30181 acctcaagat tgattcaggg atgggacgga ttggttttag agaggcaagt gaggttgagc
    30241 aggctcaaga tttgctccaa caacacggtg ttcgtgttga aggaatcttt acccactttg
    30301 ctactgctga tgaggaatca gatgactatt ttaatgccca gttagaacgg tttaaaacta
    30361 ttttagctag tatgaaggaa gttccagagc tggttcatgc tagcaattct gcaacgactc
    30421 tttggcatgt agagactatt ttcaatgcgg ttcgtatggg agatgccatg tatggtctca
    30481 atccaagtgg agcggtcttg gctttgcctt atgatttgat accggccttg accttggagt
    30541 ctgctctggt tcatatcaag acagttccag ctggtgcttg catgggctat ggagcaactt
    30601 atcaaacgga tagcgagcaa gtcatcgcga ccgtgccaat cgggtatgca gatggatgga
    30661 caagagacat gcaaaatttc tctgtcttgg tagatggcca agcttgccca attgtcggca
    30721 gggtttcgat ggaccaaatc actattcgat tgcctaagcc ttacccactc ggaaccaagg
    30781 taaccttgat tggctccaat ggggataagg aaatcactgc aactcaggta gcgacctacc
    30841 gcgtaaccat taactatgag gtggtttgcc tcctcagcga ccgtattccg agagaatatt
    30901 attagaaaag aaaggagtgg agcatgaatc tacatcaacc cttgcatgtc ttgcctggtg
    30961 tgggaccaaa gtcagcagaa aaatacgcca aactaggaat tgaaaacttg caagatctct
    31021 tgctctactt tcctttccgt tatgaagact tcaaaaccaa gcaggtgctg gaactagaag
    31081 acggtgagaa ggcagttctt tctggtcagg tagtgactcc tgctagtgtc cagtattatg
    31141 gtttcaagcg caatcgcctg cgttttagtc tcaagcaggg agaggtcgtt tttgcggtga
    31201 atttctttaa ccagccctat ctggctgata aaatagagtt gggagcaacc cttgctgtct
    31261 ttggaaaatg ggaccgcgct aaggctagtc tgactgggat gaaggttctg gctcaggtag
    31321 aagatgacct ccagcctgtc tatcgtctgg ctcagggaat cagtcaggcc agtctggtca
    31381 aggtcatcaa gacggctttt gatcagggac tggacctctt gatagaagaa aatctgcccc
    31441 agtctttact agacaaatac aaactcatgt cccgttgtca ggcagtccga gctatgcatt
    31501 ttccaaagga tttggcagaa tacaagcagg ctcttcgccg tatcaagttt gaggaactct
    31561 tttatttcca aatgcagttg cagatgctca agtctgaaaa tagagttcag ggaagtggtc
    31621 tggttctgaa ttggtctcag gaaaaagtga cagcagttaa agcaagtctt ccttttgccc
    31681 tgacccaagc tcaggaaaag agtttgcagg aaattttaac tgatatgaag tccgaccact
    31741 acatgaatcg tctcctacaa ggagatgtgg ggagcggaaa aacggtagtc gctggcttgg
    31801 ccatgtttgc ggcagtgaca gcaggttatc aggctgccct aatggtacca acagaaatcc
    31861 tcgcagagca acactttgag agtttacaga acctttttcc caatttgaaa ctggctctct
    31921 tgacaggttc cttgaaagct gcagaaaaga gagaggtctt ggagaccatt gccaagggtg
    31981 aggctgattt gattatagga actcacgctc tgatacaaga tggggtggag tatgctcgtc
    32041 ttggtttgat tattatcgat gagcagcacc gttttggtgt ggggcaaagg cgtattttac
    32101 gggaaaaagg cgacaatcca gatgtcctca tgatgacggc gactcccatt ccacggacgc
    32161 ttgccatcac agcctttgga gatatggatg tttccattat cgaccagatg ccagcaggtc
    32221 ggaagcctat tgtgacgcgc tggatcaaac atgagcaact acctcaggtc ttgacttggt
    32281 tagaggggga aattcaaaaa ggttcccaag cctatgtcat ctctcctttg attgaagaat
    32341 cagaagctct agatttgaaa aatgccattg ccttatcaga ggagttgacg actcattttg
    32401 caggcaaggc agaggtggct cttctacatg gtaggatgaa gagtgacgaa aaagaccaga
    32461 tcatgcagga tttcaaggag agaaagacgg atattctggt ttcgacgacg gttattgagg
    32521 ttggggtcaa tgttcccaat gcgactgtca tgattatcat ggatgccgat cgcttcggtc
    32581 tcagtcaact tcaccagctt agaggtcgtg tcggtcgggg ggacaagcag tcctacgctg
    32641 ttctcgttgc caatcccaag acggattctg ggaaagaccg catgcgcatc atgacagaaa
    32701 cgaccaatgg atttgtcctt gcggaggaag atttgaaaat gcgtggttct ggtgagattt
    32761 ttggaaccag acagtcagga cttccagagt tccaagtggc tgatattatc gaagattttc
    32821 cgattttaga agaagcaaga aaggttgcta gctacattag ttctatagaa acttggcaag
    32881 aagatccaga gtggcgcatg attgcccttc atctggaaaa gaaagaacat ctggattaag
    32941 ctttctctaa ggaaaactta agctagtttt tagatttggc tcttatacta aagtcatcaa
    33001 aaagaaacga ggactctcat atgacagtaa cgattaaagt aaattaccaa accactttcc
    33061 aaaagaagga agca
//
LOCUS       DAVLHM010000027        28816 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLHM010000027 DAVLHM010000000
VERSION     DAVLHM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.027"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="VXE45_001303"
     CDS             complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="VXE45_001303"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0789331.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1420..2196
                     /gene="recX"
                     /locus_tag="VXE45_001304"
     CDS             1420..2196
                     /gene="recX"
                     /locus_tag="VXE45_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0789332.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2285..2818
                     /locus_tag="VXE45_001305"
     CDS             2285..2818
                     /locus_tag="VXE45_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0789333.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3173..3658)
                     /locus_tag="VXE45_001306"
                     /pseudo
     CDS             complement(3173..3658)
                     /locus_tag="VXE45_001306"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(3691..4029)
                     /locus_tag="VXE45_001307"
     CDS             complement(3691..4029)
                     /locus_tag="VXE45_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789334.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEYYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            complement(4042..4815)
                     /locus_tag="VXE45_001308"
     CDS             complement(4042..4815)
                     /locus_tag="VXE45_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0789335.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(5261..6016)
                     /locus_tag="VXE45_001309"
                     /pseudo
     CDS             complement(5261..6016)
                     /locus_tag="VXE45_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(6154..7776)
                     /gene="groL"
                     /locus_tag="VXE45_001310"
     CDS             complement(6154..7776)
                     /gene="groL"
                     /locus_tag="VXE45_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0789336.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(7792..8076)
                     /gene="groES"
                     /locus_tag="VXE45_001311"
     CDS             complement(7792..8076)
                     /gene="groES"
                     /locus_tag="VXE45_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0789337.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(8346..8741)
                     /locus_tag="VXE45_001312"
     CDS             complement(8346..8741)
                     /locus_tag="VXE45_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0789338.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(8819..9580)
                     /locus_tag="VXE45_001313"
     CDS             complement(8819..9580)
                     /locus_tag="VXE45_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0789339.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(9613..10239)
                     /locus_tag="VXE45_001314"
     CDS             complement(9613..10239)
                     /locus_tag="VXE45_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0789340.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(10255..10572)
                     /locus_tag="VXE45_001315"
     CDS             complement(10255..10572)
                     /locus_tag="VXE45_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0789341.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(10569..10868)
                     /locus_tag="VXE45_001316"
     CDS             complement(10569..10868)
                     /locus_tag="VXE45_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0789342.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(11118..11306)
                     /locus_tag="VXE45_001317"
     CDS             complement(11118..11306)
                     /locus_tag="VXE45_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEV0789343.1"
                     /translation="MKASTWVYDKGEWYYVSSSGAMLANDWVKDNGKWYYLASSGKML
                     RNTYTPDGYYVGNSGAWQ"
     gene            complement(11557..12231)
                     /locus_tag="VXE45_001318"
     CDS             complement(11557..12231)
                     /locus_tag="VXE45_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789344.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(12237..12683)
                     /locus_tag="VXE45_001319"
     CDS             complement(12237..12683)
                     /locus_tag="VXE45_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0789345.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(12797..13300)
                     /locus_tag="VXE45_001320"
     CDS             complement(12797..13300)
                     /locus_tag="VXE45_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0789346.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(13297..13659)
                     /locus_tag="VXE45_001321"
     CDS             complement(13297..13659)
                     /locus_tag="VXE45_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEV0789347.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVHIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(13725..15584)
                     /locus_tag="VXE45_001322"
                     /pseudo
     CDS             complement(13725..15584)
                     /locus_tag="VXE45_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(15623..16072)
                     /locus_tag="VXE45_001323"
     CDS             complement(15623..16072)
                     /locus_tag="VXE45_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0789348.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(16196..16912)
                     /locus_tag="VXE45_001324"
     CDS             complement(16196..16912)
                     /locus_tag="VXE45_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0789349.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(17793..19208)
                     /gene="ply"
                     /locus_tag="VXE45_001325"
     CDS             complement(17793..19208)
                     /gene="ply"
                     /locus_tag="VXE45_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0789350.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(19219..19551)
                     /locus_tag="VXE45_001326"
     CDS             complement(19219..19551)
                     /locus_tag="VXE45_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789351.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(19622..20230)
                     /locus_tag="VXE45_001327"
     CDS             complement(19622..20230)
                     /locus_tag="VXE45_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789352.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(20243..20701)
                     /locus_tag="VXE45_001328"
     CDS             complement(20243..20701)
                     /locus_tag="VXE45_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0789353.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            20826..21225
                     /locus_tag="VXE45_001329"
                     /pseudo
     CDS             20826..21225
                     /locus_tag="VXE45_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21990..22250)
                     /locus_tag="VXE45_001330"
     CDS             complement(21990..22250)
                     /locus_tag="VXE45_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789354.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(22309..22860)
                     /locus_tag="VXE45_001331"
     CDS             complement(22309..22860)
                     /locus_tag="VXE45_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789355.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(22850..23047)
                     /locus_tag="VXE45_001332"
     CDS             complement(22850..23047)
                     /locus_tag="VXE45_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789356.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(23051..23845)
                     /locus_tag="VXE45_001333"
     CDS             complement(23051..23845)
                     /locus_tag="VXE45_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789357.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(24253..24678)
                     /locus_tag="VXE45_001334"
     CDS             complement(24253..24678)
                     /locus_tag="VXE45_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789358.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(24807..25190)
                     /locus_tag="VXE45_001335"
     CDS             complement(24807..25190)
                     /locus_tag="VXE45_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789359.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQLASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLG"
     gene            complement(25212..25418)
                     /locus_tag="VXE45_001336"
     CDS             complement(25212..25418)
                     /locus_tag="VXE45_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789360.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(25405..25578)
                     /locus_tag="VXE45_001337"
     CDS             complement(25405..25578)
                     /locus_tag="VXE45_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789361.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(25937..26893)
                     /gene="lytA"
                     /locus_tag="VXE45_001338"
     CDS             complement(25937..26893)
                     /gene="lytA"
                     /locus_tag="VXE45_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0789362.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK"
     gene            complement(27269..28639)
                     /locus_tag="VXE45_001339"
     CDS             complement(27269..28639)
                     /locus_tag="VXE45_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0789363.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         8830 a         6148 c         4892 g         8946 t
ORIGIN      
        1 cttttcaaac tttgtcaact acttttttaa acttttttta ttaattttac aacagcttca
       61 gttcgagctg tatgtgggaa catatcgacc gactggatat aatgaagatc atagacttct
      121 actaagcgta ccaaatcacg agccaaggtc gaaacattac aagaaatata aaccattttt
      181 tctggtacat aagtaagaat agtatctaat aacttatcat ccagacctgt acgtggtggg
      241 tcaacaatca aagcatctgc tcggtagcct tccttgtacc aacgaggaat aatctcttct
      301 gccgttccag cttcataatg agtattgtca aatcccattc ttttagcatt tcgcttggca
      361 tcttcaatag cttctggaat aatatccata cctctgagtg tttttacttt ctttgcaaag
      421 gcaaatccaa tcgttccaac tccacaataa gcgtcaatca aatggtcttc tttatcaaca
      481 tccagcgctt ttactgcttc gctatagagg acttctgttt gctcaggatt tagttgataa
      541 aaagctcgag gggatagtga aaattcataa ttgagtacac cttcttgaat actctcttgc
      601 ccccagataa tctctgtctt ttcaccatat atctcactgg ttttagctgt atttgtatta
      661 acagctactg tcacaacttc tgggaaatct ttaaccaact cttttaccaa ttgagttaaa
      721 ttaagctggc ggtttgtaac aataataatc tgaacctgtc cggtctttct cgcgcgtcgg
      781 accataatag tacggacacc tagaactttt ctctcatccg tgattggaat ctggtgataa
      841 gtaagtaatt ctgctaagcg attagcaatc acttgggttt ccttatcttg taccaggcag
      901 tctttcaact ctactaaata gtgagagttt tgtgcatata agcccgcctt gacctgattt
      961 ttaaattttc gagtctgaaa ttgtaactta gctctgtaat attttggttc ctgcattcca
     1021 atagttggac gaatttcata attttcatat cctgcaggag caaatttttt cagcgcttga
     1081 tgaagtaagt ccgtcttgaa ctccagctgc ttatcataat gcaggtgcat gatttggcag
     1141 cctccgcatt cattataaat agtacaagat ggcacaattc gaaatttaga cttcttgttg
     1201 accttcagta attttgcttc aacaaagttg cgtctaatag aagtaatctg acaatagata
     1261 tcttcgcctt tgagagctcc aggtacaaag actaatgttt tttggtaaaa gccgattccc
     1321 tcaccattaa ttcccatgcg tttgattttt aatggtattt tttgtttcac tttcagattc
     1381 atacccctat cttatcacat tttgagttat aatagagcta tgaaaatcac aaaacttgaa
     1441 aagaaaaaaa gactctatct gatggagctt gataatggcg acaaatgcta tatcaccgaa
     1501 gatacaattg ttcgttttat gttatcgaga gataaggtga taagcgaaga ggaattgaaa
     1561 gagattcaag actttgctca attttcttat ggtaagaatc tggccctcta ccacttatcc
     1621 tttaaagcac gcactgaaaa agaagtcaga gaatatctga aaaaatacga tattgatgaa
     1681 aacatcgttt ctcaagttat tgctaatctt aaagaagata agtggattaa tgatggtcag
     1741 tacgcttatg ctatcatcaa taccaatcaa ctttcaggag acaagggtcc ttatgtgctg
     1801 actcagaaac tagctcaaaa agggatttca aaatctacta tagaagagaa cttgaaagaa
     1861 tttgattttt ctgaagttgc tcaacgtgta gccaataaac tattgaaaaa atatgaggga
     1921 aaacttccag ctcgtgccct gcaagataag attatccaga acttgactaa caagggcttc
     1981 tcttattctg atgctaaaat tgcctttgac gacttagata gccaagttga ccaagaaacg
     2041 actcaagaac tcatcttcaa ggaacttgat aagcaatata ctaagtatgc tcgaaagtat
     2101 gaaggatacg aactgaagca gcgtttaact caagttttag cacgaaaggg ctacgatttt
     2161 tcggatatag caagcgctct tagagaatat ctttaatatt tccaagtgaa attcacagat
     2221 tttaggtaat tttatggtac aatagtaaat gataaactta taaattgtag aaagttggtt
     2281 agttatgaag cttccaaaag aaggcgactt tattacaatt caaagttata agcatgatgg
     2341 gagtctccac cgaacttggc gggacaccat ggtactaaaa acaacagaaa acgccattat
     2401 tggtgtcaac gatcatacac ttgttaccga aagtgatggt cgtcgttggg tcactcgaga
     2461 accggctatt gtttactttc acaagaaata ttggtttaat atcattgcca tgattcgtga
     2521 taatggaact tcttactatt gcaatatggc tagcccctac tatctggatg aagaagcact
     2581 gaagtatatt gattacgatt tggatgttaa aatttttaca gatggggaaa aacgtctctt
     2641 ggacgttgaa gagtacgagc gtcacaaacg caaaatgaat tattctgatg acttggacta
     2701 tattttaaaa gaacatgtca aaattcttgt tgattggatt aacaatggac gtggtccttt
     2761 ctcagaagcc tatgtaaaca tttggtacaa gcgctatgta gaactaaaga atcggtaaag
     2821 ttgtcaaagg tcaggaacaa aatcctgacc tttttttggt agtataaaat aaattgtgta
     2881 aacacaaaaa ggaataaatc tattatagca gagttacaac acattactag aaagagattt
     2941 atgcaaaatt cgtaaaatat ataaaacaaa tagatatact gttatttttt aatgtcttta
     3001 ttccttgtaa gtttacaaca aacttatatc gtttaataca aaaaatacga aaatgattag
     3061 tataaaaaat acaggtcaac ttcgtatcaa aaacattttt ttgtatttcc acatagcatc
     3121 aatcatttag tacaatattt taaaaacaat atcttaacag agaaaatgat atttaatcta
     3181 tcagctcatt taatcgtttt tgaaaatata aagcaatact tttagattca ataaactcaa
     3241 aatattttat gacattgtcc atttgtttaa ttccagattc tttagattct gtcaggtata
     3301 ttttatatcc ttctacaaat ttgaatgtag atttttcaaa aacttttgtg tcatctttta
     3361 ataatttttg taatttcatt tcaaagtagt ctgcatatat tagatgtgaa ttttcaaggc
     3421 aacagaacca aaaatttaaa caagctgaca caactaaatt tctattcttg ccgatttttt
     3481 cgtaataatg tgtacgctct agtatttctt ttccgaccat gtaaatataa tctatttcaa
     3541 aaagatgata taaattacca atcagcgtta tctcatagga ctcccatcgt tccttctgga
     3601 ataaatagtc atatactaaa tttagatcat ctctactaac tacatgatta caatctagct
     3661 gatttcataa tccctgaacc ataattgtat ttattttatg agttttttcc cactcttctc
     3721 aaaaagtttt tgttgcttat tttttattac ctccaatcct ttaatattca aactataaaa
     3781 atttggagat aaattaacca aaaaatcatc acgctccgat cttttataat attctaagtg
     3841 attacaaaaa ttctctatcg aaacattgat atttgataat aattcaaaaa atgttgaaag
     3901 agaaatttca ttttctcccc tttcaaatct agaaagttga gattttgata taaaatcagc
     3961 tgcagcatac tctaaagaat atccgtttaa ttttctaaaa tatcgaaaag cttctccgta
     4021 atttttcaca ctttcattcc cttaactttc ttttcgagcg ataaacatac catattcttt
     4081 aggaatgatc aacataccat tattaaactc actttccaat cttttacgta ttatttcctc
     4141 ttctagtgaa cctatttctg aaattccttt aaacgattgg atgtatttaa ctaggtcatc
     4201 tatactagtt acctgtaact catcatcata gagtaatgta tcgacagagt taaaatacct
     4261 actcaggtac cttttaccat tttgtaaagt aaacgttcta ttttctaaat cttgattaac
     4321 ctcatcttta aataaacttg ccaaataatt tacaactcca ttttcaccaa atgtagcaca
     4381 gtaaaaaatg cctccggttt ttaagaccct attcacctca gagagagctt taggaatatc
     4441 attcacatga tgtagaagca tattagcaat aacaatatca aaagtttcat tctcaaaaga
     4501 aatcttttga atatccatta tctcataatt gacattgttt ctatttccaa tcactgactt
     4561 cgttgatttt accatatctt tagaaaaatc tgtaacaatc aactgcttca ttttatctat
     4621 agaatcacta ttacttttcc acaattctcc tgtaccacat cccaattcta gaacctttac
     4681 ttcatcagtg atttggtagt tagaaaatat ccaattatta aatcccaatt tattttttga
     4741 atacttctta tgcaattcta ctcgaatatc aagattatca tgacttttat attgttcaat
     4801 tactttatca atcattttaa atgacctcca ctctataatt tggcattata tcacaagaat
     4861 aaagatagtg ttaaataagt tatataaatg caaaaaagga atattccgtt atagcagagt
     4921 tgtaacacat ttctataaag aaatttattc ctacgactca gtttggcatg cttaacttcc
     4981 taactcaaaa acaaagcatc gattaattta tccgttcttc ttttgaaaca gatttgaact
     5041 gataattgct cgttttaatt taaaaagctc ttttgagcaa aacttcattt ttttaagagt
     5101 ccaacaattt ctgtctatcg cttttctact agcaaaaaac ctaccttgag gcaagttttc
     5161 atttatatat ctaatttcgt aacagtatag taaaatgaaa taaggacagt caaatcgatt
     5221 tctaacaatg ttttagaagt aaaggtgtac tattctagtt tcaatctact ataaatttga
     5281 tatgagaata gtctttctca acatccttat ccaacaagca tgctgtggcg tccttcttaa
     5341 cttaaaccag gtcaatattc tgggcttggg ctgcatagac gcagccacaa taacattgac
     5401 gatagatatc atactcctca cacatctcta ctgaacgttt gtagccttga tttttcttga
     5461 aatcgttggg aagatagtgg ggcgtgtaaa ttttttgcac atcgattccg atgctattga
     5521 tagtttgaga attcttatga ggactgatgg tcaaggctga accaaagtag tcaaagccca
     5581 agtccatagc cacttgcgct gttttatcca gtcggtagtc aaaacaaacc ttgcaacggt
     5641 cgccaccttc gggctcctcc tctagccccc taactagttt tcggtattaa ttgggttcgt
     5701 agggagcttc taggtactga accgtatttc ctgtccgctc attaaaatca ctaacaaatt
     5761 tcttggtgac atagacccgc ttatggtatt ctgccttggg atggatatta gaattggcaa
     5821 aatagatggt cacatctgca tacttggtca aatattctag tgtataggta ctacaagggg
     5881 cacagcaaac atgcacgaga atggttggcc gctactcatt tttttcccat gcttgtacca
     5941 ttttctgcat gacacggtca taattaatct tctgattggg ggtcatcttg cacagaattt
     6001 cttctacatc gatcatgttc ttctcctttt tctagtctta ttttatcata taagttagga
     6061 gagctcaaat caatttagaa gtgaatatta taaaaagaag ggttagtcat tccctccttt
     6121 tgtgtttttt ataagttgtt ttctatagaa agcttacatc atcccgccca tcatacttgg
     6181 atccattgct ggagctgggg ctactggttc tggtttattg gctacgactg cttctgttgt
     6241 caaaatcaag ctggctacag atgctgcatt ttgtagggct gaacgactca ctttaactgg
     6301 atcaatgata ccttgatcaa tcatgttaac ccactcgcca gttgctgcgt tgaatcctat
     6361 accaagctca gcatttttca aacgatcgat aacgatagat ccttcaaatc ctgcattgtg
     6421 agcaatttga cgaacaggtt cttccaaagc acggagaaca atattacgtc ctgttgcttc
     6481 atctcctgtc aattccaagg tagcaacagc tggaatcaca ttggcaagag ctgttccacc
     6541 acctgcaaca ataccttctt caacagctgc acgagtagcg ttgagggcat cttcaatgcg
     6601 gagtttcatt tctttcaact cagtttcagt tgcggctccg accttaataa ccgctacacc
     6661 acctgacaat ttggccaagc gttcttgcaa tttttcacgg tcaaattcag aagttgtagt
     6721 ttcgatttga gacttgataa ccgcaacacg gtgagaaatc gcttcaggat ttcctgcacc
     6781 ttctacaata accgtgctat ctttgtccac ggtcactctc gctgcttgac caagagcttc
     6841 aattgtcgca tctttcaact caagaccaag gtcttctgtg ataactgttc cgcctgttaa
     6901 gatggcgata tcttcaagca tggctttgcg acggtcacca aaaccaggtg ccttgactgc
     6961 tactacgttg aaggttccac gaatcttgtt caaaacaaga gttggaagag cctcgccatc
     7021 cacatcatcc gcaataatca agagtggacg attgctttgg agaatgcttt ccaaaagtgg
     7081 caagatttct tggatattgg aaattttctt gtctgtaatc aaaatgtacg gattttcaag
     7141 gtcagccacc attttttcgc tatctgtcac catgtactgt gaaaggtaac cacggtcaaa
     7201 ctgcattcct tctacgactt caagctctgt ttccatacca cgtgactctt cgatggtgat
     7261 gacaccgtct ttgccaactt tttccattgc ttcagagatg tactcaccaa ctttttcaga
     7321 acgagaagat acggctgcaa cttgagcgat agcttcttta ttggcaacag ggatggcgtt
     7381 gtttttcaaa gcttcaactg ctgcggcaac tgctgtttca atcccacgac gaataccgat
     7441 tggatttgca cctgctgtga cgtttttgat tccttcacgg acgattgctt gggtcaaaac
     7501 agttgcagtt gtagttccat cacctgcgat atcattggtt tttgaagcta cttctgatac
     7561 caatttggca cccatatttt caaaatggtc ttctaattca atttctttgg caatagtcac
     7621 accgtcattg gtaatcaatg gtgagccaaa tgatttttca agaacgacat tgcgaccttt
     7681 tggtcccaaa gttactttaa cagtatctgc aaggatatcg acaccacgga ccatggctga
     7741 acgggcatct gatgaaaatt taatttcttt tgacatactt actttctcct tctattcttc
     7801 aatgattgcc aagatgttag cttcgcctac gatgatgtac ttttcatcgc catctttgac
     7861 atcaagacct gcgtgggctt caactaagac acggtctcca gttttaacac ttggagcaac
     7921 caagtcaccg ttcaaggtac gaacaccttg tccagtagcc acaacttggg ctgttttggt
     7981 tttttcttgg gctgaacctg cgagaacaaa gcctccaaca gtttgttctt tttcttctac
     8041 ttttaagacc acacggtccc ctaatggttt caacatctga tttcctccat aatgagatag
     8101 atattattag cactctttat acctgagtgc taattcatag ttctattgta tcacttagtc
     8161 agaaataatc aagaaaaaag tctgactttc tcaagataaa aagcctgaga ccaactcaga
     8221 ctttttaatg tttatactca atgaaaatca aagatcaaac taggaagcta gccgcaggct
     8281 gctcaaagca ttgctttgat gttgtggata aagctaacgt ggtttgaaga gattttcgaa
     8341 gagtattaaa atggcaattc ttcctcttcc aagactaaat ctgccaaatc ttggcctgca
     8401 ttattttcac gcatggcacg ttgagcacga ctttccaaga gttggaatcc tgttacaagt
     8461 acttcggtca cgtagttcat ttggccattt ttctcaaagc gacgggtacg caattctcca
     8521 tcaacggaaa tgagactacc tttggttgcg tagcttgcca aagtttctgc tagtctgccc
     8581 cataggacca tattgacaaa atcagcttca cgttcaccgt tttggtcttt gtaacgacgg
     8641 ttgacagcga tagttgctcg cgctaccgac ttgtcattgt tggttttgtg caattctggt
     8701 gtagacgtta aacgcccaat catgataact ttattataca tattttcttc ctcctactta
     8761 tctattcgta ggaaatcaaa aaaagttaca gaaatttgta acttttcgag gaaatttctt
     8821 attttttatg aatcatgaaa cctgtcgcct gttgattggc cataatggtc atatctgtaa
     8881 tctgaacacg gcgaggctga ctggtcacat agactactgt gtctgcaata tcctgagctt
     8941 gcaaggcttc tattccttgg taaacggacg cagctcgctc tttatcacca tgaaaacgaa
     9001 cagttgagaa atctgtttcg acaatcccag gctgaatggt tgtcaccttg atatccgttg
     9061 cgatggtatc aattcgcagt ccatccgaaa aggtcttaac cgcagccttg gtagctgagt
     9121 aaacagcggc accagcatag gcgtagattc ctgcggttga ccccatattg ataatatgac
     9181 cttgattgac ttttatcatt gctggcaaga aacagcgagt aaccgccatc agacctttaa
     9241 cattggtatc caacatggtc aacatatcca actcctcata gtcttgatag ggagccaagt
     9301 caagagccag tccggcgttg ttgaccaaga tatcaatcct ccctatcgtt tctagaatat
     9361 cagagcaaac agtcttcacc atgaccatat ccgtcacatc tagtggaaaa gtccagacgg
     9421 tttgatttgg aaagcttact gcaaactccg acttgaggat ttctaatctg tctatccgtc
     9481 gtcctgttag aacgacatcc tcaccctgct ccagataagc acgcgcaatc gcttcaccga
     9541 ttcctgaggt tgctcctgta atcactacat tttttgccat cttatttcct tctatcagat
     9601 gctgacaagt tcctaggcag tccagtgttt cgctgggtcg aacggtgttc cgacaacttg
     9661 gtcttctgat aattcaagca ccccacgttt ttgtggagca tttggcagat gcaattcacg
     9721 aggactgcac atcataccaa aactcttttc accacgaagt tcacctggga aaatgagatt
     9781 cccttttggc atcatagctc caggaagcgc gacaatggtt ttcaacccca cacgcgcatt
     9841 gggagctcct gcaacgattt gtacagtctt atcacttgcg actgcaactt ggcagatgtt
     9901 gaggtggtca ctatctggat gggctaccat ctcaacaatt tcaccgacaa caaacttagg
     9961 ttccttatca ttaacaattt cttctgtaaa accttccgcc tgcaactctt ggttcaaacg
    10021 agcgacttgc tcatctgtca aaaagacttg accgcgctct gcaatttcaa ataaacttga
    10081 aacttcgaaa atattccaag ccactgtttc cccattatct ttgagaaaaa cacgggctac
    10141 cttgcctttg cgctccacat ccagtttggc atctccgcta tttttcacga tgaccataag
    10201 gacatcaccg acatgttctt tattatatgt aaaaatcatt gtttcctttt tctcctattt
    10261 cagtcctgct aaaaagtcat tgatttgttg cttgctttta cggtcgcgat tgacaaaacg
    10321 accgatttcc ttgtcctttt ctagaacaac aaggctaggg attccatata catcccagag
    10381 tttggccaaa tctatatact ggtctctatc cactcgaata aaggtaaact ctggattagt
    10441 ctcctcaatt tctggtaagg caggatagat ataacggcaa tcgccacacc agtccgccac
    10501 aaaaaggaag accttcttac cgtctttttc tactaaagat gccaattctt ctaaacttgc
    10561 tggttgtatc ataagacttc ctcctcatag actaggtctt cattttcata gacaaaagta
    10621 taatgacggc catcctcaaa aatgacgcca ccaagcaagc tctctagact gctttcatag
    10681 acttgaacat agagggtcgc aatttccccc atgtctgaaa aatggtctcg tacaatcgct
    10741 gtcaactctt cctgagtctt catgagctta tggtcatctg caactttttt cgtagcaagg
    10801 gcaaggctcc caataccaag cagagccaga cctgccatcc acattttttt agctttcata
    10861 ccattcattt taacacaaaa aaggctttag gacaaatgag gaaacagcaa aaaagcaagt
    10921 aaaaagcctc ttcctttaag gaaaaggact tcttatactc aatgaaaatc aaagaccaaa
    10981 ctaggaagct agccgcaggc tgctcaaagc actgctttga ggttgtagat agaactgacg
    11041 aagtcagctc aaaacactgt tttgaggttg tggatgaagc tgacgtggtt tgaagagatt
    11101 ttcgaagagt attattctta ttgccaggcg cctgagttac caacgtagta accatcaggt
    11161 gtgtaggtat tgcgaagcat cttacctgat gaagctagat aataccactt gccattatct
    11221 ttgacccaat cattcgctag catggctcca gaagaactta cataatacca ttctcccttg
    11281 tcataaaccc aagtgcttgc tttcatggct cctgagcaat taaaggttca aaaaactgtc
    11341 caatatcatt cattttttta aagcatttta cactacatca tccacgctgt aggacataga
    11401 tacatcaaac gtaagagcca aaatatcgaa aaatatacaa cttttaaagg caacatttca
    11461 ttttttaaag tctaacaacc atagaactga aatcagagca aggcatcaac ttcctactct
    11521 tagtacgtct attttgatgg ttgaagtgaa gattttttat ttaacgtaga caagctccaa
    11581 cttcccaaaa gccacatctc cacggataat caaggttttg ctggttgggg ctacaggagc
    11641 gtcagcctta gctgcaccaa aggaggtttc tactttcaaa tctacacgcc agtgttgtgg
    11701 aacatagacg gttgcattcc cgaaggccac ttcaatattt aaagttgcaa aatcacctag
    11761 catctctgca ttatcatagt agattttagc atccccaaaa gcgacttcca cttggtcatc
    11821 tacgagatct tgatcttgct tatagaaggt cccgctacca aaagcgactt ccttatccgt
    11881 gacgactgtt tttttcccat tgtaccacca ttttttttca ttccagaact tacttgaatg
    11941 cgtcagataa ccaacaccaa gtaccaccaa gatgctagcc caaataagag aatgattggt
    12001 aactggtaac aagtcataag cgtaatttgc aatgatgagc gccagtaaac ctgtaaaaac
    12061 tgccgaagtg agatgacgtc taaggatgga ctcaatggac ttataagcaa aaaaaacaat
    12121 acctagtaaa ggccatattt taccatccaa agaaggaatt ccaaaattcc cttgcagcaa
    12181 gatccaagct gctaaaacca ataaaacaat accaaatgct ttctttttca tgttttttac
    12241 ctcatgtttc ttagattttc ttttaggagg gattggtaat gccgtgagac atgaacctcc
    12301 ttgtgcgtct gataaaagga aatggtgccc gttcctgaaa aggacttgtc cactgagtaa
    12361 atctgacgga tgtttgcgat cgttgacttg gaaactcgat taaaatagcg aggcaagata
    12421 gactccaact catagagctt gaggcgaacc tcataagctt ccttctggtt atgagcgtag
    12481 atcttgctcc cttctgtttc aaagaagaga atttctgaca ggtctagata atattcacct
    12541 gtccccttgt aaaaagtcaa cctcggagcc tttgactctt gcaagagccg ttgcaagtct
    12601 gcaatttcat ctgtcaaagt gggggtcttg atgacaattt cagtctcctc taaattgccg
    12661 tcaatctcaa ttcgtaactt catcacatct cctttctgac tctactatat caaagctaag
    12721 ttaggaatac aagggcaaaa aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac
    12781 tagcttaact tacatgtcag aataggaaga aaaggaatcc ccacaccaga ccacaagcat
    12841 agccaaccaa gacatccttg ggataatgaa caccccctaa aaccctcacc aaccccagca
    12901 aagctgaaaa gatcaagcat actaagccaa taggtagact agcatgcaga caggccatgg
    12961 agatgatagt tgcagaaaag acatggcgac tgggcatcga ccgtcccgaa ctatccttat
    13021 caagaagggg acagatatcc caagtttcat aaggtctcgg gtgattgatt ttcttacgaa
    13081 acagggacaa ggccacaaaa cctgatgcag gaataagcac ataaacccca acttgctgac
    13141 caagtcctag ttgcaggtaa gtggtgacta gcaagatcag atagaccagg ggcatggcga
    13201 ctgtcatcaa acgattgaaa ctgcgtaata ggaataaaag aattggacga ctagttagtc
    13261 tggagctgat atttcgatac cattcttgat aatttttcat ttatgcttct catacttttc
    13321 tagaacttgt tgagatgttt tccccttggc aagccaatcc actagcttgt ccaaacgacg
    13381 tatttcctgc atcagaggat catcaatttc ctcaatatgg acaccgcaaa tcttccctgt
    13441 aattgcaatt cgttcaggga cataatatgg tgcttgtaga aaaaaatctc cgtaagtaac
    13501 atccctatcc agacaagcaa gaacgtcact cacttcatac cctgtcaacc aactggtcac
    13561 ttggtgaact gactctgcct ttccaccctt tcgctcaact tttgcaatca aggctaagta
    13621 gacagcagca aatttcatat tgtataattt ctgactcata cttctctctt tctatgtgta
    13681 ctagtataaa taagaaaaag aaggccgtca agcctttttt tgatttattc ttctgcttca
    13741 tcttctgtaa attgactatt gtacaagtca gcgtagaagc caccttgcgc catcagttcc
    13801 tcatagttgc cttgctcgat gatatttcca tctttcatga ccaagatcaa gtctgcattt
    13861 cggatgattg acaagcggtg ggcaatgaca aaggatgtgc gtccttccat caaacggtcc
    13921 atggcttttt ggatcaattc ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa
    13981 atcaaaagcg atgcatcctt aagaagggca caagcaatag tcaatagttg tttttgtcct
    14041 acagacaagg tcacggtgtc atccaagatg gtatcatagc catctggcaa ggtcataata
    14101 aagtggtgaa ttcccacagc cttactagct tccatcattc gttcatcact aatccctatt
    14161 tgattataga tgagattgtc tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc
    14221 attgaaaagg catcatgcac ttctgaacgc gtcatagcct tggtatccac accatcaatg
    14281 cgaatacttc tcttatcaat ctcatagaat ttcatcaaaa gattgacaat ggttgtctta
    14341 ccagccccag tcggcccaac aatggcaacc ctttgaccag catgagctgt cacagagaag
    14401 tcatagtctt gaacattgac accgtccacc agaatttctc ctgctgacac gtcgtagaaa
    14461 cgtggaatca gattgaccag agttgattta ccagaacctg ttgacccaat aaaggccact
    14521 gtttgaccag tttctgcttt aaagctaaca tgttcaataa ctgcctccga atttgccgca
    14581 tagcggaagg tcacatcctt aaactcgacc tgacctttga agttttcatc agtcagctgc
    14641 acttgaacag ggttttggat agaagaatgc aaatctaaaa cttgattaat ccgcttagca
    14701 gagaccatag ttcggggaag aacgatgaag agtgctccca tgagaaggaa gcccatgaca
    14761 acctacatgg cataagacat gaaaataatc atgtcactaa agagaggcag acgcgctatc
    14821 ggagcagcgt cgttaatcac ataggcccca atccagtaaa tcgctacact caaaccactt
    14881 gaaatcccca tcatgatagg attcaaaata gccataagac ggttgacaaa caaattcaaa
    14941 cgggtcaatt catcatttac tgctgcaaat ttttcatttt gataatcctc tgcattgtag
    15001 gcacgaacga cacgaatacc tgttaaactc tcacgagtga tactgttcag tttatctgtc
    15061 aacccctgaa tcaaggactg ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg
    15121 acgttgacaa tcactaccac aagtacggcc cagagccagt attctgaatg acctaaaatc
    15181 ttcccaatag cccagatagc cataattgga ccacgcgtta ccacttgcaa gcccatagta
    15241 atcaacattt gaacttgagt aatgtcattg gtagtacgcg tcaagaggct aggaattgaa
    15301 aatttcttaa tctctgtctg cgagtaatcc aaaactcggt taaaaatatc acttctcagc
    15361 ctactagtat aagaagccgc cactcgggat gcaaaaaatc caactgcaac tacggacaag
    15421 aaggcaagaa aggacattcc catcatcatg cttgccggct gccacaactc atctaaatta
    15481 gtttcttgac tacctagcaa atccgtaatt ttcgagatat aggtcggcac ttccaactct
    15541 agatagaccg aaaagcaagt aaagagaatg gctagtaaaa tcatccccca ttcttttcta
    15601 ctaattcttt tggctaattt ctttattctc tcctcctatt cccttgatat tttgcctgta
    15661 gttgaccgag aaccttctca aaaatcagta attcatcttc atcaatatct tccatcaact
    15721 gcttgtctat gcgttcaaaa aaagccttaa cctgttgcat ctgagaacgt gctttgtccg
    15781 tcagacgaac aaacttagcc cgcttatcaa caggactcgc ctccaattcc accaaaccat
    15841 tttgcactat acgcttaacc agattactag caacagactt ggtaatattg agttcctgat
    15901 cgatatcttt aatcaagacc aagtcttggt ttttctcgcg attatccaaa aaatgcacaa
    15961 cctgaccttg cggcccaccc ataaattcaa tgccgcaacg tttggcttcc ttttgcacca
    16021 tcaggtgaat ttgatgacca aaacgcttaa agactaacat cggtttaccc ataatctccc
    16081 ccttctaaat aaaaatagtt ctctggagaa taattaaatt tctatgagaa ctattttctt
    16141 gattaaaaaa atcccaagtg attttctcac ttaggatcat gttctatagg ttaaattaaa
    16201 acccatctac gttcgtataa atcttttgga cgtcttcgtc gtcttcaaga acgctgtaaa
    16261 gtttttcaaa ggtttcaagg tcttcgcctg acaattccac ttctgactga ggaatcattt
    16321 ccaattcagt cacttggaat tcttcaatac cagactcacg gagggcaacg atagccttgt
    16381 gaaggtcagt tggcgctgtg taaactgtga ttgtaccttc ttgtgcttct acgtcatcca
    16441 catccacatc cgcttcgagc aattgctcaa agactgcgtc cgcatcttca cctccaaata
    16501 caataacacc tttgttgtca aagaggtaag aaacagaacc tgaagcgccc atgtttccgc
    16561 cgtttttacc aaaggctgca cggacattgg ctgctgtacg gttaacgtta gaagtcaaag
    16621 tatccacaat tagcatagag ccatttggcc caaaaccttc gtaacgtcct tctgtaaagg
    16681 tttcgtctgt gtttcctttg gctttatcaa tcgctttatc gataatgtgt tttggcactt
    16741 gggcttgttt agcacggtcg ataacgaatt tcaaagctga gtttgattct ggatctggat
    16801 cacctttttt agctgctaca tagatttcta caccaaattt tgcatatact ttagagttgg
    16861 ctccatcttt agccgttttc ttggctacga tattggccca tttacgtccc attaggaatc
    16921 tccttttttc acattttaat ctttcttatt ataacacaag tttttttgat tttcactaga
    16981 ggaaatggat tttattagca aatcaagcta ggatagcact ttacctgcta agatggtctt
    17041 gcctttctat ctttatcaac agacactcat ccacattcaa aaaacaaact agaccattat
    17101 ctgcaaatag aaagtttcag ccaagtttga caaagtcagc tcaaattact gtttgaagtt
    17161 tgtagatata agcgacaaaa acaatcatac tgcacctttt gttgacagtc tactccagac
    17221 atatcatagt tcaagtaaat actttgaaat tcaacagttc ttataggcgc tattgtattc
    17281 taagaaatca atagaagagt ttctaagcaa acctctaata ctcaataaaa atcaaagagc
    17341 aaactagaaa gctagccgca ggttgctcaa aacactgttt tgaggttgcg gatagggctg
    17401 acatggtttg aagagatttt ctaagagtat aatttacgtg ttcctaagat ggagaagtta
    17461 gactagtaca ctggcacttc taaaccattg ctagcaattg atttgttcat atttaatttc
    17521 attttttcca taaatgggta ttagatataa acagcaaaat atttccgata cgtgtcattc
    17581 ttgaatttcc aatcatctaa aacaagtaaa ggataatcaa tcccctgtat atcaaggaat
    17641 tggctaccct ttttactttt ttacacatcc tgtttgatag actcatttta acatcacgag
    17701 catactccaa tggaaatcgc taggcaagag ataaactttc agatatccgc agagagatca
    17761 tcgcctcttt ttgtcgcaag cattctcctc tcctagtcat tttctacctt atcctctacc
    17821 tgaggataga gagttgttcc ccaaatagaa atcgtccgct tacgcactag tggcaaatcg
    17881 gttttttcat aaaccgtacg ccaccattcc caggcaagcc cggtacactc tctaattttg
    17941 acagagagat tacgaacatt cccttttaaa ggaatactag tggtaaagtg agccgtcaaa
    18001 tcctgcccat ttctgtccca agccttagga gtcaagactt ccttaccttg atgatcatag
    18061 gataattcat cccaagtaat ataatattgg gcaacatagg caccactatg atccagcagt
    18121 aaatctccgt ttctgtaagc tgtaacctta gtctcaacat agtctgtact gttttgaaag
    18181 gtcgcaacta cattgtcacg taaaaaagaa gttgtatagg aaatcggcaa gcctggatga
    18241 tctgctgtaa agcgactgcc ttcttgaatc aagtcctcta ccatatccac cttgcctgtt
    18301 acaactcggg cacccgaact tgggtcgccc cctaaaataa ccgccttcac ttctgtattg
    18361 tccaaaatct gcttccactc tgtctgagga gctaccttga ctccttttat caaagcttca
    18421 aaagcagcct ctacttcatc actcttactc gtggtttcca acttgagata gacttggcgc
    18481 ccataagcaa cactcgaaat atagaccaaa ggacgctctg cagaaattcc tctctgtttt
    18541 aaatcctcta ccgttacagt atcttgaaac acatctcctg gatttttaac agcgtctacg
    18601 ctgactgtat aataaatctg cttaaaatta acaatctgaa tctgcttttc acctgaatgg
    18661 acagagttaa aatcaatatc aagagaattc cctgtctttt caaagtcaga accaaacttg
    18721 accttgagtt gttccatgct gtgagccgtt attttttcat actgcattct agctgggaca
    18781 ttattgacct gaccataatc ttgatgccac ttagccaaca aatcgtttac cgctccgcga
    18841 acacttgaat tgctggggtc ttccacttgg agaaagctat cgctacttgc caaaccaggc
    18901 aaatcaatac tataagtcat cggagcacga tcaaccgcaa gaagagtggg attattctct
    18961 aacaaggtct catccactac gagaagtgct ccaggataga ggcgactgtc gttggtagct
    19021 gttacagaaa tatcacttgt atttgtcgac aagctccgct tctttctttc gataacaaca
    19081 aactcatcgg gtagctgatt accctctttg atgaaacgat tttcaatact ttctccctga
    19141 tgggtcaaga gtttcttttt atcgtaattc atagctagta taaagtcatt tactgcttta
    19201 tttgccatct tctacctcct aataagttcc tggattgagt tgcataaact cagacttgtt
    19261 cagcgaaatc agccgtggtt ggactaagtg atccaaaatt tcctcgtaca attcttctga
    19321 gacattgcgt cgccgtctgg ctagataaga agtcggaata accgtattat ccaacataaa
    19381 taccttatct aagtcaatca aggttggtct tgtaaaagga ttacgagcta gatccggctc
    19441 ttctatcata aagttcttga ccaaacgtct ggtcaagaga gctggtttga aggtctgatt
    19501 tttaaccaac tctttgtttt tagtcatgct gttgtcaata cagatataca tatgattctt
    19561 cacagccaaa tcgctactaa tagtcggaaa aggcaaataa agagctacaa catctcctct
    19621 cttaatcaag caagagcacc cccttttctc ctaatgtaac atagacagga ttgaccaagt
    19681 cttctgattg actcagaatt tccaaagttt gagtttggcg cgctgtcaat ttagtagcat
    19741 cttgtctctt caatacaaaa tgcttgtcgc caataacctt gacaatataa tccttctcca
    19801 aagctgactg gtaaatccac atcagatgtt gtctgtcctg agaactcaag agagaaggat
    19861 tttcaagcct cccgatagtc tgataaaaat caaaaacagg agctaactcc tgccaatctg
    19921 attggctagt tgtcaaggct agaaaaaggg ctttgcgagc tgatacttct tggttagcct
    19981 tgagagttac tttcccctcc aagtttttta gaaatcggga aactccagaa agcaaatttt
    20041 tctctaactg cgagaaataa aaacctttcg ttcccagaca taagtctttc atgtcgcttt
    20101 ctctagcaaa taagagctca aacatttgat agtaaaagaa aaatatctgg cactgggtcg
    20161 cgctcatctt ttccttatcg gcttcttttt ttaaccagag caagggcgac aggtaactgg
    20221 attgagacat ttcctctacc tcctactctt ttttaactgg agcatctgca ctagctgcca
    20281 cttcttttga ctggatactt tcccactggt taatctcctc tgagataaga ccttcgcatg
    20341 tcttgacaaa tagggcaaaa gccttggtct ttcctgcata tttctccgtt tggcattgat
    20401 agaggaattt ttctttctcc aggagttgcg cagttttttg gtaagaaatc caattttcct
    20461 ttgcattata caaattgata atcccctcac acagcaagcc gagactggat aaggcaaccg
    20521 aaatcaaacg gtagcgatca cctggcatag gaatagcaca aaagacagct atgaggaaac
    20581 ctgccacgat ttctgttatt tttaatacct tatagcgcct acgatgttga acgcttttct
    20641 ttaaaaaatg agctatctgt acgtctaatc gctctgtcag gtacatttct tctggcgtca
    20701 tattcgtaac tcctttcatt tactttgata accatagtat aacatatttg aatatcaaag
    20761 tatagtaaaa actggactat aacttattag acttcctgcg aaacaaaata tggtatagta
    20821 gttctatgaa tgatgaagca agtaaacaac taactgatgc acgatttaag cgtcttgttg
    20881 gtgttcagcg taccactttt gaagagatgt tagctgtatt aaaaacagct tatcaaaaaa
    20941 gtcggacaag ctggtaaaat cttggctgac agtaattatc aagggctcat gaagatatat
    21001 cctcaagcac aaactccacg taaatccagc aaactcaagc cactaacagt tgaagataaa
    21061 gtctataacc atgcgctatc taaggagaga agcaaggttg agaacatctt tgccaaagta
    21121 aaaacgttta aaatgttttc aacaacctgt cgaaatcatc gtaaacgctt cggattacga
    21181 atgaatttga gtgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct
    21241 attatatata tgcacagaca tatgaaatct ttttgataca gccttctttt tacatagaga
    21301 gacagcagtt atgatatatt tatccattca caacatcttc tgtaccaata ctacaataat
    21361 tggtacattt tgattacaca atcgtttcaa aaaatatgat ggaagactga gtattttata
    21421 gtaattccct tcctatcaac tagatcaacc agttgagtgt tgaatgttga aacaccctag
    21481 cctcagcaaa ggactatgat cagcatttcc tagccaatag gacgctccaa atcacctatt
    21541 ctaagtccat cactagcttg gtcagtaaga tacagactgc aaggcaagac tgacgtggtt
    21601 gatgagattt tggaagagta ttacaatcat agattcacca gtagacttga ccgcagattt
    21661 aactatagta gattgaaact agaatagtac acttctgctt ctaaaacatt gttagaaatc
    21721 gatttgactg tcctgatcaa tttgtcctgt tctcgtttca ttttactata ctaaaaaacc
    21781 acctgaaaca aatcaagtga ctagaggata aaaacaaaga ctgggcaaaa agttttgaaa
    21841 agcaaaaaac gcataatatc aggtcttgaa aaaccttgat actatacgtt tgattgtggg
    21901 aagattgact tcattttctc ctgaaattga agttttttct agtttccagg tatagacgaa
    21961 ttcaatatag ccatctcgct acaattattt taaccatcga aaaaattttt cagaatttca
    22021 aaaatttcat tttgatccaa tgaaatgtca ttattttgaa gaatagttga cttcacaggc
    22081 tctaattcta tcacaaagcg gtgcatgtct gcttttaccg cactacttga tgttatagcc
    22141 gataactttt catctcctag caaggaagct gtcaaacggg taaggtcatt caaatgcttt
    22201 ttaatggact tacttaaacc ttgagcacct gtggcagagc gctccctcat atccagccaa
    22261 gctttagcct taaaaataat taatactcaa tgaaaatcaa agagcaaact aggaagctag
    22321 ttgcaggctg ctcaaaacac tgttttgagg ttgtagatgg aagctgacgt ggtttgaaga
    22381 gattttcgaa gagtatagac cacaattact caataccgaa tacccctgaa tggtttcttt
    22441 tacatgcacc aatatattat aataatcttc atccaataat aaggctgata aactagcatc
    22501 ttggtcaaaa tataagggaa tttctcgacc gtccttcttt aatggatatt ctggtaagat
    22561 actaaatagt tcaatcatag aaggaaactc agaattagtt gttgtaaatc gaaaaagctg
    22621 cgctttctca tctttctgac ttccttgata ctctcccaat tctaaaaaat gattcaaggt
    22681 agtataaaat tccttatttt ttacttcatc aatgatgacc atatcataat cttttgttgt
    22741 gcgactttta aatccttgcg aatccaatac gatagaggta gcagttcccc caatcagaac
    22801 ataatagttc tgaaaatccg caaacatttc ttgaaaaata actttcgtat tagctggcat
    22861 catcttctcc cagatactgt aatatcatat tttctagtgc ttcactctct tcctctatac
    22921 gtgggtcatc atcatctttt aaggtcaaat aaagagaaat cggatctaca aattgtttat
    22981 catgattatt tttaaaatca ttccaaaact cagatacaaa aggacgatat ttccatatct
    23041 ctagcatctt tcattttaaa acatgctgag aaagtggcaa ggataactga ttgaattttc
    23101 tctgccatat gacatagcta atattttcat ccgtttcagc taaaaaagtt gaatgcgaca
    23161 aagcataagc accaccatat agaaggttag aaacagattt tatctgcttt atatcgccat
    23221 ctggcaataa aatccgtttt ttgatgggat taaataaaca tgacacggat tttaagaata
    23281 attctttctt tgacaccgta tatgtgtaaa gcttattttg cttgtttaac caatataaag
    23341 ctttaaaagt cctcaaacac ctataaattg ttgagtttgg aagtccagtg acttgtgaaa
    23401 gcaaatcaac atctactact ttttgacctt ttgtcaataa aaaggcaatc cacgttaatt
    23461 gttcgctagg tgttaattcc ttagggactt cagtatcatt cgcattgagt actagtccca
    23521 atggagggaa gaagaggttt cccttaaagt ctacaaacgg aactctagct tgaagtaatt
    23581 gctttttttc actgtctgat aacttcgaaa acaccaaaac aacatccata ttggcttttt
    23641 cacccatagt gcgagcctga gtaacaaatg aactcaaact cccccttctc ttttctttaa
    23701 tcaataaaaa tgattcctta tgaaaagtca tttgagtata ctcaaacctt tttacaaaac
    23761 tgattggtaa agtcaaagtc agttcctcaa tactgacatc aacataaaag gattgaaaaa
    23821 ttgacattat ctttttgaca ttcatgtttt ttccttattc tatcattttt attatatttt
    23881 atcattcggt ataataaaat ataagttttt tgataaaata accaaaaact actcgctatc
    23941 ccctctcaca ttaccctaca tatcgtttga catgcgactg atagttcagg aaaacttcaa
    24001 ggagaacttt tctctcatcc actatgcagg acttactatt tcacttctac tcctataggc
    24061 tcaatttgac acttttcttt ttcgaattgc tcatatgcct cctgaatagt gagttcgatt
    24121 tatccaaatt tatttttgtc tattttgatg aatacttcca cgaagatagt ctgaaaatga
    24181 atttgcacca attttccttc tctttttaag catattattc cagatatgat tgccctcttg
    24241 ttcagtaata aattacgctt taaacgcttc aatcagtata tctcctgttg tcatatgttc
    24301 taaagaaaat tcttctacat atgatttaac atctcttagg ttattacttc ctaatatccc
    24361 attatgcttt ttcgctaagg aaatagaagc cgcttctccc ttaccaataa tcttgttatt
    24421 atcatgattt cttgttaaat ctctatataa tgcgtattct tcagttccaa tgtctatgct
    24481 cacaatctca gctgaaccct tagctaccaa ctgatctatc ctagatttta aatggggaat
    24541 tgtaggtata ttgatttcat catacacctc ttgtggaata acaattttac ccgaatagag
    24601 cttttctaaa agatgttcag tgccaaccca taaaaatact gaaatacaat ctgcatcaat
    24661 aaatacacga ctagtcaaac gacaactccc ccctcttcat ctagcccata tacaatatca
    24721 tatctgaaag catctagtaa cagttcctca tacttccctt gcgaaattct gttattttct
    24781 aaaagttgtt cagttgaatt aatatattat cctaatacca tttccttttt actttctgac
    24841 aaaggacgat ataaacttgt atcatagcct aatcttgaag ctgtctctat aacactaata
    24901 tccatatttt taatttcttc tgcatcaagg tatccatcat tcctcaatct atataacata
    24961 gctttatgac tgataccata aaactgaccc aattttataa tatcttctac ttcaagatga
    25021 gttctattgg cattttctct gatttcctca accatcctat acagtgaaga tgggaaaatt
    25081 aaaaaataag aagcaagctg atccgctttt ctttcagttt catctccttc accaatcaag
    25141 ataagactga ctgaactctt cttcacctca tcataataaa gatgatacag ttcatgtgct
    25201 aaagaaaatc tttaccttcc taatgacatg tctgaattga ctgcaatgag actgaactga
    25261 gttcctttat aacagactcc gctaatattc tttccgagtc cataaaatac cagcgtcaaa
    25321 ttttctatct tttgtaccaa tttaaaaata tctatcggcg cttcaccatc agctcccaac
    25381 ttttttctaa gatttgaagc tttattactt aaatccattc gtgatattcc tttcaccttt
    25441 ttccattttg gcaatcatgc tttgattcaa agacaaatat aaagacaaat attcagcaat
    25501 cttatcttga gtaagatttg aagatattct aagttctttt attctttttc caacatcaca
    25561 tacatttatc acatacattt atcatattca tacacctctc ataaaaagaa tagcacactt
    25621 ttgtcataat tttttaaata aaaaaattat gacaaaacaa ggaagcaatt tattgatgct
    25681 gcttaaaaat ctaaaattga tgagttccta tcaaaaatcg tatcttcaac ctcaaaacag
    25741 tacttaaagc tatccgactc ggtttacatt gtcaaattta gattttattt gagcataact
    25801 ttctagtttg ctttctgatt tttgtttaat atagtagcaa acattgaagg aaatatctcc
    25861 acaagaaaac gcatactatt aagctttttc aagacctaat aatatgcgct gttctgattt
    25921 gaaagacatt ccattattat tttactgtaa tcaagccatc tggctctact gtgaattctg
    25981 gcctgtctgc cagtgttccg tctggtttga ggtagtacca gcctgttccg tccgctgact
    26041 ggataaaggc atttgatacc atggcgcctt ctttagcgtc taagtagtac caagtgtcct
    26101 tgtacttgac ccagcctgtc ttcatggcac cttcttcgtt gaaatagtac cacttatcag
    26161 cgattttctt ccagcctgta gccatttcgc ctgagttgtc gaaccagtac cagttgccgt
    26221 ctgtgtgctt cctccagcgg tctgcaagca tatagcctga actgtcaaag tagtaccaag
    26281 tgccattgat tttctcaaac ttgtcttttg gataagagcc gtctgaatgt acgtaccagt
    26341 agccagtgtc attcttctgc cagcctgttt caatcgtcaa gccgttctca atatcatgct
    26401 taaactgctc acggctaatg ccccatttag caagatatgg ataagggtca acgtggtctg
    26461 agtggttgtt tggttggtta ttcgtgcaat actcgtgcgt tttaattcca gctaaactcc
    26521 ctgtatcaag cgttttcggc aaacctgctt catctgctag attgcgtaag agttcgatat
    26581 aaaggcggta gtccgtcatg aactcttctt tggttgaatg gctttcaatc agttcaaccg
    26641 ctgcataggt ctcagcattc caaccgcccc caacgtccca ggcaccatta tcaacaggtc
    26701 ctacctgcat gatgcaaccg ttcccaacaa tgtgcgagaa aaaacctaat tctgggtctt
    26761 tccgccagtg ataatccgct tcattctgta cggttgaatg cggattccca gttgagtgtg
    26821 cgtgtacttg cctatatggt tgcacgccga cttgaggcaa atctgttctt aatttactca
    26881 cattaatttc catattctac tccttatcaa ttaaaacaac tcatttttta caatccagaa
    26941 ccagaaactc ctttatttct accttacaaa gaagacaatc ttagtcacga ttaggcttgt
    27001 agatagaact tcaaaacgca ctattttgac actgtaaata ggactgacaa ggtctgcatt
    27061 ctatctacaa taacacccca gactaaaaag cttttcaaaa gtatattttt acagtctcta
    27121 tatgtccttt tcataaatac tatactttat tatatcatat aaaagaagtc aaaagtctgt
    27181 taaactattt tcaacaccaa actaaagacg agaacacaag ttttttcgat tttcactaga
    27241 ggaaatggat tttattcagt aaatccaact aggattgcac tttggttgcc aagattgcct
    27301 tgccttcttt tatcaaggga tgacggaata atgagaagta cagttgaact gtcatggcaa
    27361 cccagataag aggttcacaa aggataacac ccttatatcc tgcccaagga ataatcaaaa
    27421 ccacaaaaac gatttttccg attagttcaa taaagctaga aactagagga aggatctttt
    27481 gccccaagcc ctgcaagcaa ttgcgataaa tcaacaagag gctcaaaatg ggataaaagg
    27541 ttgaactgat ttgcagatag agacttccat tttctatcaa gtaaccatct gtcgaactag
    27601 ccaagaagga aaccaaagct ggactggcaa aaaagaggaa aatacaaaca aaaactgccc
    27661 aggatatact taaacgactg ccgattcgaa gaccttgaac aatacggtca ggtcgcttag
    27721 ctcctagatt ctgagaagca aaggtcgtca ttgatgcaga aatagcggtc ataggaagaa
    27781 gggcaaaggt cataatgcgt cgagctgccg tctgggcact aataatcact gcaccaaatg
    27841 tattaacaga aaactgtaaa atcacactgc cgatagatac aattgaactc atcaagccca
    27901 tagccaaacc ttgctccaag agatccgcgt acaagctttt gtcccatttg aaatgtttaa
    27961 actgtggcaa gagttctggc acacttttac gaatataata aaagcagaga accgctgata
    28021 aaccttgcga aataatggta gcaagtcctg cggattgaac tcccagatgc aattgcgtaa
    28081 taaaatagag atccagaacc acattaacca aggcagagaa aatcagaaat cccagggctg
    28141 ctagactgtc accaatagac cgcaacaagc ctgcaaaaag attataagca aagctgacac
    28201 ctacacaggt cacaatcata gaaatatatt gataagattg aggaagaatt tctgcaggag
    28261 tatctaagta ttgcaagaga ggatacaagc caagaaagcc cagcaacata actagaatgc
    28321 tcaaaagagc acctaaaatc caggtggctg ctactgcttc cttgatttta gtgaaattcc
    28381 gagccccata ataacgagca atgacaatcc ccatgccatt gccaacacca agtgtaaagc
    28441 ctacaatcag gtcaaaaatc gctgtcgtcg ctcctactgc agccaaggat tcttgaccaa
    28501 gaaatcgtcc aacaatcaag acatcagcag tgttatagag ctgttgaaaa atatttgata
    28561 gcaagattgg aaaggtgaag cttaagagcg agggaagaat cggaccatgt atcaggtcca
    28621 ctgttcgttt tttattcata aagctattat atcagctttc cagaggagcg acaagaaaca
    28681 gcaaacttat atatagcgga atgaaataag gacagtcaaa tcgattttta acaatgtttt
    28741 agaagtagat gtgtactatt ctagtttcga tctattatag ttggttgagt ttggaatagt
    28801 acgctgtagc tgctaa
//
LOCUS       DAVLHM010000028        25624 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLHM010000028 DAVLHM010000000
VERSION     DAVLHM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.028"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(151..2256)
                     /locus_tag="VXE45_001340"
     CDS             complement(151..2256)
                     /locus_tag="VXE45_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0789364.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     TKHLEADMEDGVLVIREKA"
     gene            complement(2865..3845)
                     /locus_tag="VXE45_001341"
     CDS             complement(2865..3845)
                     /locus_tag="VXE45_001341"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0789365.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(3847..6099)
                     /gene="pbpX"
                     /locus_tag="VXE45_001342"
     CDS             complement(3847..6099)
                     /gene="pbpX"
                     /locus_tag="VXE45_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0789366.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(6103..6420)
                     /gene="ftsL"
                     /locus_tag="VXE45_001343"
     CDS             complement(6103..6420)
                     /gene="ftsL"
                     /locus_tag="VXE45_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0789367.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(6432..7382)
                     /gene="rsmH"
                     /locus_tag="VXE45_001344"
     CDS             complement(6432..7382)
                     /gene="rsmH"
                     /locus_tag="VXE45_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0789368.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            7548..7742
                     /locus_tag="VXE45_001345"
     CDS             7548..7742
                     /locus_tag="VXE45_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789369.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            7758..8300
                     /locus_tag="VXE45_001346"
     CDS             7758..8300
                     /locus_tag="VXE45_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0789370.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            8311..8553
                     /locus_tag="VXE45_001347"
     CDS             8311..8553
                     /locus_tag="VXE45_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789371.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            8564..8899
                     /locus_tag="VXE45_001348"
     CDS             8564..8899
                     /locus_tag="VXE45_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789372.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(9009..10010)
                     /locus_tag="VXE45_001349"
     CDS             complement(9009..10010)
                     /locus_tag="VXE45_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0789373.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(10070..11971)
                     /locus_tag="VXE45_001350"
     CDS             complement(10070..11971)
                     /locus_tag="VXE45_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0789374.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHYSKDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIRVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(11993..12286)
                     /locus_tag="VXE45_001351"
     CDS             complement(11993..12286)
                     /locus_tag="VXE45_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0789375.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(12286..13104)
                     /locus_tag="VXE45_001352"
     CDS             complement(12286..13104)
                     /locus_tag="VXE45_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0789376.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(13091..13870)
                     /locus_tag="VXE45_001353"
     CDS             complement(13091..13870)
                     /locus_tag="VXE45_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0789377.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(13885..14376)
                     /locus_tag="VXE45_001354"
     CDS             complement(13885..14376)
                     /locus_tag="VXE45_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0789378.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(14387..15577)
                     /locus_tag="VXE45_001355"
     CDS             complement(14387..15577)
                     /locus_tag="VXE45_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0789379.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(15589..16023)
                     /locus_tag="VXE45_001356"
     CDS             complement(15589..16023)
                     /locus_tag="VXE45_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0789380.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            16297..17112
                     /locus_tag="VXE45_001357"
     CDS             16297..17112
                     /locus_tag="VXE45_001357"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0789381.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            17131..17772
                     /locus_tag="VXE45_001358"
     CDS             17131..17772
                     /locus_tag="VXE45_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0789382.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            17803..18804
                     /locus_tag="VXE45_001359"
     CDS             17803..18804
                     /locus_tag="VXE45_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0789383.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            18814..19443
                     /locus_tag="VXE45_001360"
     CDS             18814..19443
                     /locus_tag="VXE45_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0789384.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(19822..20207)
                     /gene="tnpA"
                     /locus_tag="VXE45_001361"
                     /pseudo
     CDS             complement(19822..20207)
                     /gene="tnpA"
                     /locus_tag="VXE45_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(20560..23639)
                     /locus_tag="VXE45_001362"
                     /pseudo
     CDS             complement(20560..23639)
                     /locus_tag="VXE45_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            23862..24338
                     /locus_tag="VXE45_001363"
     CDS             23862..24338
                     /locus_tag="VXE45_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0789385.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            24580..>25624
                     /locus_tag="VXE45_001364"
     CDS             24580..>25624
                     /locus_tag="VXE45_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0789386.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQNKKPEKFFGL
                     IEDNLKQVHPIFQT"
BASE COUNT         7494 a         5691 c         4574 g         7865 t
ORIGIN      
        1 tttttttcag ctggctcctt cttttttatc ctcaaaattc tatcttatac tcaatgaaaa
       61 tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggcaa ggcgacgttg
      121 acgtggtttg aatttgattt tcgaagagtc ttaggctttc tcacgaataa ccaaaacgcc
      181 atcttccata tctgcttcca gatgtttagt atctaaatga tccaagtgga agtctgtcac
      241 cttatcacga atttcttgtt caaccacgcg acggagagga cgaaccccca tgacttcgtc
      301 gtaaccttct tctgtgatat aatctttagc cgcttgactg actaccaagt caatgtcttt
      361 cttagccaag gtttggttaa cttcagccaa catcaaatct acaatcttag aaaggtcttc
      421 cttagtcaat tgtgagaact cgatgactgc attaaagcgg ttgaggaatt ctggacggaa
      481 gaagggtttc aaacggtcca tcaattctgg tttatccgca tcttctgtca agttggcttc
      541 atagccaaat ccagcatttg aggtcgcaat aatgacagtg ttcttgaagt ttactgtatt
      601 tccttgacca tctgtcaaac gaccatcatc tagaacttgg aggagaaggg taataacttg
      661 aggatcagcc ttttcaattt catccaagag aatgatagag tatggattgc gacgaacacg
      721 ttctgttaag gtattgctat tgtcatcata acccacatag cctgctgttg taccaattag
      781 cttagaaaca gctgtgcggt cactgtattc agacatatcc aaacggataa tcgcatcctg
      841 ggttccaaac atatcgagtg ccaattgctt agcaagctcc gtcttaccaa ccccagtaga
      901 ccctacaaag aggaagctgc cgattgggcg atttccttca tcaaaaccag cacggttacg
      961 acggatagcg cgagctacag cttctacggc cttatcttga ccaatcacct tgtcttgcaa
     1021 gcgatgagcc atatctttca aacgttcgat atctgaagct cccatttgcg atactgggat
     1081 acctgtcatt cgttccacag attcagccac atcgttgaca cttgcagtca ctttcatatc
     1141 ttctgtgtgg ttttcgattt tcttttccaa ttctgcaatg cgtgttttat agtttagagc
     1201 tgcttcaaaa tcttctgctt caactgcttt ttcttgcttg tctttttccg tttcgatttc
     1261 tcgttcaaca gcatgcacat ctgttactgg atgttgagcc gccaagtgag cagccgttac
     1321 atcgacaagg tcaatagcct tatctggcaa gctacgttga ggaatgtatt gaacagaata
     1381 atccaccgct gctttcaaga cttcgtctgg caagatgaca ttgtggtgtt gttgatagag
     1441 gtcacgaatt ccttgaagaa ttttaaaagt attctctgcc gaaggagcat tgaccttcac
     1501 ttcgttgaaa cgacgagcaa gagcagcatt cttcaagatg gtgttacggt attcgtcttg
     1561 agttgttgcc ccaatcactg tcaattctcc acgagagaga gctggcttga gaatatccgc
     1621 aagtccttta gaaccactgt ctccaccagt gctaccagca ccaagaattt ggtgaatttc
     1681 atcaaagaag aggataatat tccctgcttc tttcacttca ttgactaagt tttggacatt
     1741 ttcttcaaag ctaccacggt attgagtacc agcctcaaga cctgagatat caatagaaat
     1801 aatttccttg ttcttgatag cagcaggaac atctccgttc acaatggctt gcgctagacc
     1861 ttcgacaact gctgtcttac caacacctgc atctccgacc aaaacaggat tgttcttggt
     1921 gcggcgtgag aggatttcag atgtttcttg aatttccttg tttcgtccga taacaggatc
     1981 caacttgccc tcacgcgctt ctgctgttaa gtttcgacct agttttgcaa ggacaccgtc
     2041 ttgtttcata cctgatgcct gttgtggcat ttgcacatca gtttctgcat ttcctggtaa
     2101 ttgaccagtc gcacgatagt gagcaaattc ctcaggtgtg acttcgcgtc cattaattaa
     2161 gtaacggcga ttttcagaac tgtatcctcg cataccaccc atcaattggt taaataaatc
     2221 atccatgtta ttaaaattat taaagttgtt attcatattc tttacctctt tttgtttact
     2281 tagttatgat tactgatatt gactatcttt gaccattgtt ttaaaaaatt tagactagct
     2341 agatcgctac cctacgtact atttctggtt tttctttttc aagcaggagt agactatctt
     2401 tacttctgaa gatttctaga tgaaacatag acccacctct ttctatttta ctttaaataa
     2461 gtgttctagt aaggctttca tttaccttac gttcataata tactacattg gtcagaaaag
     2521 gtcaagagtt ttgactttaa ctgaccaata tttttttaca ctcttcgaaa acctcttcaa
     2581 accacatcag cttctcctta tctacaacct caaaaccgtg ttttgagctg acttcgtcag
     2641 ttctatcaac catctcaaaa ctgtatatta aaacgaaata agaacaggac aaatcaatca
     2701 ggacagtcaa atcgatttct aacaatattt tagaagtaga tgtgtactat tctagtttca
     2761 atctactata ttttgagcag cctaaagtta gctttctagt ttgttctttg attttcattg
     2821 tgtatttaaa cacaaaaaca ccctgaaaca tcagggtgcc attcttacat caaatataaa
     2881 attgctaggg tcaggagact tgctagaagt cccactcccc aaaagaagaa gtcaaccttc
     2941 cactcgctcc aaggatttcc tttaccagac aatcccccaa gctcaaaatg gtgatgtaca
     3001 ggcgtcatac ggaaaatacg tttaccacct gtcagtttga aataactgac ttgcatcata
     3061 acagaagttg tttcaaaaac atacacaatt ccgataatca agagagtcca ttcttggtgg
     3121 agagccatag agatagctgc cagcatccca cctagggcca aacttcccac atcacccata
     3181 aagaccttgg caggcttatg gttaaagatg aagaaaccga gcaaaccacc aatcatggca
     3241 agaatcacta gaagaatatc catctgacct tgcacatagg caataactcc ataggcagac
     3301 aaactaatca caacggaaat actagctaaa ccgtcaacac cgtctgtcaa gtttactgcg
     3361 tttgaaaaac cgactagcca gaaaagagcg aagaaaatat agaaaaatcc caaatgaact
     3421 ggataaccaa agacagacag gatatcgcca ccgcgctcat agaaaagata gaagataact
     3481 ccacctagaa gctgaagagc taatttttgc ttaggattaa gcccctcatt gattttacga
     3541 aagaccttga gaaagtcatc taaaaatccg accaagccat acaagaccaa gatgaacaaa
     3601 atcattccca cattattgct gaattggcta ctaaataggg cgaaaaagaa agcaaccaaa
     3661 acagaagtaa tcaagaaaac caaacctccc attgtaggag tcccagcttt tgcctgatgc
     3721 tgtttgacat cttcatgcat ctgctgtcct gtaatttgcg cctttctata aaattggata
     3781 aaggccggaa ttcctactaa agttagtaaa aatgtcacaa ttccagcact gatggaaata
     3841 aacatattag tctcctaaag ttaatgtaat ttttttaatg tccttgatag ctgtgttagc
     3901 acgaacatct tgcttctgca cagtagagcc cgaaccttga aattcaagtt ctatattgag
     3961 ccacttagca agggtctcag cagtctcctt tgtccaacca tacatatctg gaacttcctc
     4021 tgctttatca gataagataa ggacttgctg attcggggca agattcttcc cttcttcagc
     4081 agaactgttt ttaatcttcg ttcctgttcc cacaacgatg ggttgtacaa gattgcgacg
     4141 caattcttct gctaaatcac caggtgaaat atccttgaca ctaggcatag gataaggact
     4201 ttgttgactt acttgctcca aagctttagc tgttgtttga agattgagag agtctttcat
     4261 agctgaagcc cgctccaaga taggattggc aaattctccc aactgaatac ctgaataatg
     4321 ttcaggttgt tggaccgtca catacaagat aaaatcagga ttttcagccg gactcatcga
     4381 tacagccgag aaaatatagt cggttacccc gactagataa ccaccatttt tctcgtcagc
     4441 aatctgagcc gtaccagact tgagggctac attttgccca ggaacagtta cagttggctt
     4501 gcctgtgctg tggttataca tggttccata aaccggatcc gtccctacca aaaccatgtt
     4561 agtccgagtt agactagctg catctttaga aacaggattt cccacaattt ctttttgaga
     4621 tttccgagca gtttgatcat ttggatcata aatggcacta ataaatttag gctccagcat
     4681 gacaccgtca ttagcaatag ctgtaaaggc acgaatcatt tgcgtctggg tcactgaaat
     4741 cccttgtcca aatgagcttt gcgcaatgtt gacaatatta tccgcaggaa gctgaccagc
     4801 atactcatcc gtcaaaccga aacgggtcgg aactccaaat ttaaaacgat taagataatc
     4861 aagccaggta gcatctccca tcttttgctc aaggagggtc atcccaacgt tacttgagtg
     4921 tgcaaaacct tgagaaaaag tcatcattct gccaccagtc aatccttcat taacgtccca
     4981 atctcgaatc gtggcatctg caatttttaa ctcactacta ttaaagactt ctcctcctgg
     5041 aaaggtatta ttatcaatag cagcagccaa catcatcact ttcatagtgg aacctggctc
     5101 atagttactt tggtaaagga tatcacgcca aacaaagtcc tctgtaatgc cttcttttgt
     5161 atctgcatca aaggtcggtc gttgcgttgt tgccagaatt tcccctgttt tagcactgac
     5221 caaagtcgct gtcatgtact ttccttttac cttctcttga aaagcatcca tctgggtttc
     5281 cataaaggac tggagggggc tggaaatggt tgtataaaca tccttaccgt ccatcgttcg
     5341 ttgggaaact tgttctgttc cgggtacaat attacccaga cgatcctttt cataggtaat
     5401 aatgccgtct gtccctgcaa gaatactgtt caaggaactc tccattccag aggttcccag
     5461 caagctcttg cttccatctt cattttcatg gagctgagct aggccgataa aactagaagc
     5521 aaattgtccg tttgggtaac tacgattggg actggttgta aaatcaatcc ccttgacctc
     5581 tgcagcttcc aattcttttt tgatagacat catattggca taggtaatcc catttccctt
     5641 tgctccaaag gaaacttgct tgagattagg ttgcgagagt tgctctctta cataggattc
     5701 ttccatgtcc aaatacttat gaaagacctc tgcaaccttg ttaaattgtg ttttttctac
     5761 gtaaagaatc ttacccgttg ctgacttata gttctcatca atgaccgcat agacattata
     5821 ggaggttgca tcctcagcaa tcgggactcc atttcggtca taaatagtcc cacgtttggc
     5881 aggaactgta cgggtggttt gatgaacttt cttagcttcc ttcgctaaat ctgttccaaa
     5941 gcgagtgcct gtcccaataa tgaccgcaaa attgactaaa aaaatggcaa aaacaaagac
     6001 agataataaa ctcagacttt ttccaactct gcgtctgttt tcagccggcg atttccgatt
     6061 tttggtcgca taacggatta ctctttttgt ccacttcata tcttactccg ctattctaat
     6121 attttcattg tttaattgca aatcgtgtga attggcaatt tctttcaaac gttctgcacg
     6181 taatagttca ttgacctctt gcttggcatc gtccaattcg gttttctttt cctctatctg
     6241 cgcattgatt tttgtcaaat cattctgcac ttgcaagagc ttggtctgca taaaaataat
     6301 actaatggct acaataagag tggttacagc aatggaaaag taaaaagctt tttccacacg
     6361 cgaaaaccgt ttaagttgca tctgtagtat ttgacctgtt ttttccattt tttctgccat
     6421 ctttttccct cttacttgtg aatttttctg gccacgcgca acttggctga gtgcgagcgg
     6481 ttattggctt ctaactcttc cgcacttggc aagattggct tacgggacac caattccatc
     6541 ttgggcttga gatcatctgg gatgaaaggc aagccttttg gaacttcaac tgttgaagct
     6601 tccttgaaca attgcttggt caagcggtct tctaaggaat gaaaggtaat cactgaaatt
     6661 ctaccatcca gagccaacat atccatagcc tgctggatgg actcatctgc cgcccccagt
     6721 tcatcattga cttcaattcg aatagcctgg aaaatctgct tagcaggatg ccccttcttc
     6781 ttgagttcct tggcaggttt gaccaacttg ataatctctg ctaactcagt cgttgtctca
     6841 atcggcttca cttcacgcgc ttgctcaatc ttacgcgcaa tctgtttaga gaatttgtcc
     6901 tctccatact tgaagaaaat acgaaccaag tcatgatagt cataattgtt caccacttca
     6961 tacgctgtca gactagcatc ctgattcatc cgcatgtcca gtggcgcatc ctttttataa
     7021 gaaaaaccac gctcacgctg gtctaattga ggactagaca ctcccaagtc ataacaaatt
     7081 ccatcaattt cctgaacacc agcttcgcgc aaacgtgcct gtaaatgacg gaagttgtcc
     7141 ttgataaagg tcaccattcc cttctcaatg taaggtgcca agcgtttttg cgcattgtca
     7201 atggcattct gatcctggtc aaaggcatag agatggcctt tttcacttaa tttacttaat
     7261 aaatactcgc tatggcctgc tccacccaaa gtcgcatcaa cgtagatacc gtcaggtttt
     7321 acgtcaagca tatcaatcgt ttcgtggagt aagaccgtta catgatgaaa ttcttttgtc
     7381 atatcttatc tattttacca caaatccgac cagcttgcac ttgtcagaca aataggacaa
     7441 ggagactact atttcttcaa aaaatatgtc aaaaatactt gacactttat gtttaaaaga
     7501 ctataatata gtcaaatata tacgacataa atcagaaagg agaccagatg aatcgtgtga
     7561 aagaatttcg caaggaattg ggtatttccc agctcgaact cgccaaggat atcggtgtct
     7621 cgagacagac tatcaatatg attgaaaacg acaagtacaa tccaaccttg gaactctgtc
     7681 tcaatctcgc ccgcagcctc caaactgacc tcaacagtct cttttgggag gaagattttt
     7741 aaaaaaggag caaactcatg aaaaaagaaa ccttcactga aaaactgatc aaacgcacat
     7801 acggtatttc tggtcccctt gacgaataca aacggcgtga ggccgatagt attgggaacc
     7861 aagtctttat cgtcctcttt tatctgatga ttttcggaaa tattattcca ctccttctgg
     7921 cctataaata ccctcaagaa gtggctctaa tctatcctcc tctgatttta gtgattgccc
     7981 tcatcgcttc tggctatgtc acctaccaaa tgaaaaaaac aggcatcaca gtcattgaac
     8041 cagatatgct gaatgagaaa gaaagcaagc aactacacta ccctggtctg aaagcaggtt
     8101 tgttctttgg tctatggatg ttttttataa ctcctcttct cagtatactc atagatgaag
     8161 gtcaggacta ttttcattct cttctcacta taagaaatgg tgtatcaagt attctcggtt
     8221 ctattttctt cggagcgagc atacagttcc tcatctcccg tcgcattgca aaaactaaga
     8281 aaaatcaaga tgaggattag gaggaaactc atgaaaaaag aaaagaaaca gttacgttat
     8341 cctggtctga aagcaggttc gatttatgga acagtgatat tttttataat tccactcatt
     8401 gataccctaa caagtgaaaa tccaaatttt atcagttctc ttctaaatac aaaacatatt
     8461 tttaaaacta tactgggagc tttctttttc ggagtgatga tacatattgt cgactcactt
     8521 cgtattgcaa gagctaaaaa agaccaggat taggaggtgc cttatgaaat cactagctag
     8581 actactgatc attcatgttt ttatcagtat tttccttttc ttcgccctta cttcaggagc
     8641 tatttctcat acagttttac tactcctact cctctttctt cctgcgctca ataaaggact
     8701 tgagaaaata caatcaaaac ggatacctgt cctcaacgca gccctcttct ttctcctcat
     8761 atcctttcca caacttttaa ccaaccctgt ccaatggaaa ttttcaatat tcctagtcgt
     8821 aaccatcatt tcaagtttgg cctacttcta taacttttat caagtagtta aagaagtaga
     8881 tcaaaaacag ttgatttagg agcttgctcc cataatttct cattttatag gcaaataatc
     8941 ccacctagct tgttctaggt gggattattt tatttcttaa cagagattgc aagtcatttt
     9001 ccttcatttt agaaagtcga ctctttccaa ttcacactac aatccaagac ttgttgcctt
     9061 tcttcttgat tgcgaccttc aatctggtca atcaaaatct ttgtagcctg ttgtccttcc
     9121 tcaaaggagg gctgaaccag cgtcgaaaca cttggagaag aaaagcaagt ccactccgta
     9181 ttgtcaaaac caatcaaccc aacttgcggc aagttataat tcaactcttt gataacggta
     9241 aagactagag gtagggccca acagttaggg ataaatacca gagttttttc atcgggatcg
     9301 atttcttttt gtaaaaattc tttaatttgt tccaaattcg tatgcttatc ttcaatggtt
     9361 agactggcgt gacgcatatt agcatctgtt aaagcatcca caaaaccact tgcccgctca
     9421 atccgagtac tcaaacgact cgtatccgct gtaatcaaga gaaaatgttc ataacctttt
     9481 tcgatacagg actgggtcat gtcataaacg gcatcatagt tattggtttt aacccagcta
     9541 gtccggtgtt catagagctg actatcaaaa aagaccattt tcttcttttt ctcatcgatg
     9601 atacgagaat attttcggaa attagaggtc ggctgaataa taaagccgtc tactcccaag
     9661 agaagcatgc tttcaatata ccggtcctca ctctcttggc tgtaattact atttcctatc
     9721 attacctggt agccattctg gctggcgata tcctcaattc ccttaacaat ttggtttgag
     9781 aaactgttgg taatatcacc aatcaaaaca ccgattaatt ttgttcgttt ggagtttaag
     9841 ctacgcgcaa caatgctcgg tttgtaattt gtttcatgaa taactttttc aatcttttca
     9901 cgtgtctctt gggacatttt ttcatatttc ccgtttaggt aaaatgacac ggttgttttc
     9961 gaggtctgag ccatttccgc aatgtctttt atggtcagtt tcttctccaa tctaaaacac
    10021 ctcctactaa tacttattat aacatattca ctattcaaaa tgcctatttc tagcactgca
    10081 agcgaatcat tctctcattt attttatcat atactagaca ttttccacgc atttttgttc
    10141 cgtcaacgag gcacaatttt tcacctacac gaatatcctc gcttaataac agaatcagct
    10201 tgtctgtttc gtcatttttc acttcaaaag ccagagcatt ttccacttca cgatcatctg
    10261 tctggtagac agaatgacgg atgatttcaa aactctcatg cgcaatgatg gtataatcca
    10321 gcatctgatt ctcaaagaat tggcgcttgg tgagtttgct acttctttca agctcattgt
    10381 atttaggaga aatgatggta tcttccaaat caaaatcaac ttcactccat agtctcaact
    10441 gattgatttt cccatcttga taggtcacat ccttgtcaag gataaactga gtcaacgcct
    10501 catgctgacc ttgacacctg atgtcatcta ccaagagcca gacatcctct accaacatga
    10561 ggatttttct cttgtgaaga taaggcaaat caggttctgc tgaccaataa gccccttcaa
    10621 tataatgcac tccctccctt tctttatggt gacaaaacag ggagtgagga tagtattcat
    10681 attcccagga tcccgtgatt ctttccggag ctttcccatc tacaatgcag gtcgaatgac
    10741 tccaagcact ctttaagaga taacgttcat atatctcccg ataagaataa cgcccagcat
    10801 ctatgaaaat aggttggcct tgatactgta agcaaaaact attctcgtca ctatggctat
    10861 gggcacttcc tagcggacca tttttgaaaa atagataacg atgttcatcc ttaatgcaga
    10921 catgtccaga gtcttcaaag atcatggact taggctgcca agctctcctt tcaaattcct
    10981 gcagtcgctt gaccttttct cgccccagga acaagaggct aagcaaatcg actttaacat
    11041 ccagaccgtt aagaaggtct tccttgttca aaaccacagc agacagactc aaaatttctg
    11101 tcgtttctgt agaatcgcta tcaccaaaag ccaaagttcg tccatctaag cctgtcatca
    11161 tttgaatata ggtcgccatc ttttccagca actctcggta actatcttgc aagtctggaa
    11221 gcaagagaca caaatccagc aaggctttat aaacctctac atgatagaga atcgactgtt
    11281 caaactggct tccatctcct aaaatctgtg tctcaatttg ctgtttcaac tcctctgaag
    11341 caaaatggta agcttcttct agatccatct tatctgaaaa gaaataatag atagcaagca
    11401 tcggaattgt ttgtaaaatc ccccagttac taagggtgta cttggcgcga tagtggcttt
    11461 tcataaagtc aatctgcttt tctagactga ccaaaatttt ctctagttct ttctcctcta
    11521 gcaagtcaaa tttcaagagg agcaagagta gtttcaacca agtaaaggaa cgaatacccg
    11581 tatccaaggt tctagtcatc aaggattgag gagaaaattc tctcacctgc tcaatccaat
    11641 caaatagaaa gaacttgcac ttttgaatat agctcttatc tccttctacc acatacccta
    11701 tcataaactg caagagatat tcttgtcgat tgagcatata agcccattct ggatcatctt
    11761 caaatacttg atcccatacc atcggctgga tttgatggat ttttgaacaa ggctccatat
    11821 cccaaggact atcaaacata aaacgattgt ccatcaagcg ttcaagggaa cgcttgactt
    11881 tctcatagtc ttttgaatag tgggacaaga tataatcacg acattggttt ccatcgattc
    11941 tttcaaaaaa ttgtcttctt tcttctttca ttatctatta ccagaaaaag aactacttaa
    12001 aaagcagttc ttttgtcttt cccattacac tttccttttc tacatagatg accacacctt
    12061 ttgcaatctg caaggagacc aagtcatctt tgatagaaat gatttttcca tgaattccag
    12121 acaataacaa cacttcatca ccagatgtta aagaagctaa atactcttgt cgttgctcca
    12181 tctgtttgcg aagcaacttt tgctgacgaa tagaatgaaa gcttgacagt aaaaggggac
    12241 tcactgccaa gacaatcact attccataaa acaatgttgt atccattaag ctataatctt
    12301 aagccagctt ccgataattc cgatgataac tgttaaaata acgagtttat atgttgtcca
    12361 tttcttttct ttgatcaagt agtaaactaa aagtgtaaat agggctggta gaagagctgg
    12421 agcaacctta tcaagcattc cctgaatact tacgatactt tgtttagcgt ctgctttaac
    12481 ttcccctgca gcaaaggtaa tcggcaccat aatcttaaca gatgtcgctg ccaaaccagc
    12541 aattacggtt acaccgataa tattggcaat acgagaaatc gttgccatct gctcgcttag
    12601 tttatcaatc acagttgttc ctagtttgta tccatacaga ccagttgaca atttaatcgc
    12661 tgttaaaatc gtattcatcg caaggaagaa caagattgga ccgacaacca agccttcttg
    12721 agcaaacgaa gctgcgatgg ttgagaacaa tggagctaaa cagaattgag aaagagaatc
    12781 cccaatacct gccaatggtc ccatcaaggc catcttgatg ctacgtgttt cttttgttgg
    12841 tcgaccattt tccaacatta caagatgcaa gctggtaata aaaggcagga agtgtgggtt
    12901 ggtattatag aattcacagt tttcttccaa ggcttggtag aaaccttcct gatcctctcc
    12961 atagtgtttt ttcaaagcag gatacatcac attggcatat cccaaccctt gatagttact
    13021 atagttaaat ccattttgac aaaagaatgc ccgcaaagac gttttaagat aatcacgttt
    13081 tgttaatttg ttagatccag tcatcgtgtg cttcctcctc taccacatga tccgctgttt
    13141 ttggcttgtt ataaaattca atcaaagcaa agatagtacc tacaattgca ataccaattg
    13201 ttgggatgtt tagataagct gcacaaacat atcccaacaa gacaaaggga atcaactctt
    13261 tcttagccat cactgacaag atcatcgcaa aaccgatagc tgggagcatt ttaccagcaa
    13321 ctgtcaaacc tgtaagtaat accggtggaa tgtagtctac gagtttcaac aaggtatcca
    13381 ttgaaagggc acccaagcaa cccaaggtaa atccaataaa ggcaaacaac caaattgttg
    13441 catttagagt gaacttaaat ttcttcaaat tatggttttt caagtgcttc atcgctgttt
    13501 caggcgcacc agcacgtaca gtgtaggcga aagtttgtaa gaattgaatc gccacagcaa
    13561 tcggagtaga gagggcaaga gccgcttctg gactgacttt accagcacta gtgatagcca
    13621 tcaaggtacc aaagatacca ggtccgattg ggtttggtgg aacagtacct ccagcaccta
    13681 caccgaatcc catataagcc aattcaccaa tagctcccat tgcaagagca gtaggcagat
    13741 cacctagaat aattccgaca ccaaatgaca gaacaataca tctattggtg taaattccta
    13801 acagcattcc actaaaacag aaagctgtcc ataatccaat taaaatcgct tgaaatacat
    13861 taatcgacat aacgatctcc tcttttaaat atagtccata atgttgactt gaacagctcc
    13921 atcatttcct gttggagttg ttttcgtatt aaatgttact tgatgagttt ggctcaattc
    13981 cttgagggct gccttgtcct cttcacccag gaagatggag cgtgtcactt gctctttacc
    14041 aggggcattg tgaatgttcc caatattgat ttctttgata gggacaccac cttctaccaa
    14101 ggttaaagcg tcctttacat cctttacaac gataaagatc gtttgagcag gattagcctt
    14161 gtgaatgata tcaatcacct tttgcaaagg gaagaaacgc atggcaactg agtctggcac
    14221 aactgttttc atcagagttt gttgcatctt gtccgtgctt acttcgtcat tggcaacaat
    14281 gaccgtatta caacctaggt attttaccca aagttgtcct tgtccatgaa tcaaccgttc
    14341 atcgatacgg gtcataataa tatttggcat tgtcatattt ctcctcctac caatataggt
    14401 tccagtcttt gtagaaacgg ataagggctt ctaggtaata gtagtcaccc cagatattgc
    14461 cttcatccac tcctttacct gaatgccatg agtacacacc gtggaggaga cttgtcccac
    14521 caggggtaaa ttgatcattt gcataatgtt cgatcaagga acgaagcatg gcatgcatag
    14581 catgtttata aatatctttg tcagcatcca cctctgggag atgttttagc atttcatgaa
    14641 tcccacagac ggcgatagct gttgctgaag aatctcgtga ttgatcacta ccatcattaa
    14701 aaatcaaatc ccaataggac acatgatctt ttggcagacg attcaagaaa taattggtca
    14761 cacccttaaa caagtcaaag caggactcgt cttttaagtg acgataagtc aaaggaatac
    14821 catagactcc ccatgattga ccacgtgccc agcatgaatc atcactatac ccttgtctcg
    14881 ttacaccttt aaagggttga cctgtctcag gatcaaaata gaaggtgtgg aaggacgaag
    14941 cgtcatcacg gattacatta ttagctgaag catagaaatg actttctgca atatcgtagt
    15001 atttttgatc acctgtttct tgataagcaa agaataagag ttggatattg agcaagcagt
    15061 cgataatcaa acggtaatgc tctttcttgc ccaagtctcc ccaagcttga ataaaaccac
    15121 ctttttcttg atagcgttca atcaacttat ctgcagcttt caaggttgct tctctagcct
    15181 ctccatctcc atttatctta tattcagcca tacaagacgg tgtgtacaag aagccgagat
    15241 catggtgatc caattctact ctcttattga cacgatccag gaaagaaaga acatttttat
    15301 gagcgatgtt tttaaatgca tcctgttgac tgtattcata agccaaccac agttctcctg
    15361 tccagaaacc attggtccat tccgtgttat ccatgattgg atagacatta tcaaaggtag
    15421 ctggcgtcgg gaaatcttcc ttgaaatagt caaggttgag ttctaactgc cgaataacct
    15481 tatcgattgc ctggccgact tcttctttcg tcagaagtgg tacttctaag aagcgctcag
    15541 gcgattttat tttttcaatc gtaacctttt ttatcattct tttacccttt aaatacccga
    15601 ttcgaaatct tcttcctctt cctctgcatc cgttgaaaac aattctttac catttacgac
    15661 tccgccctgg gccgccacta ctgatttatt aacaacctca tcaaagctat gagccattct
    15721 agcaaagact gcttccatta acatggctaa gttcaaaccc gagagaacat tcattgtttt
    15781 ggctggattt tctcccatta tggtagaaga aaccttgaat ggcgatcctc ccaagagatc
    15841 acttaggatt aaaacttctt cttcatttga aattgcaagt aagatttttt gcttgagttc
    15901 atctgctgac attccttcca caaagtcaat cgcctccaca ttttcttgat tgcctgcaat
    15961 caattgtaaa gaactataaa tccctgtagc aaaatgtcca tgccctacaa gtacaatttt
    16021 catcttttct cctttcttgt ttaggtttac cggtttactt tatattcccc attgtaatcc
    16081 tttattttta tcttgtcaat agttttttaa aaaaaaaata ttagcgcttt cattatcttt
    16141 ttaaccattt taataggcag aaatttcaaa atcttccgtt tttttaggaa aacaaacctt
    16201 tttataaata aaaatattta tttattgaca aaaccggttt actagaatat aatttggtta
    16261 tagagaagtc ttaacaaatt tgaaaggaag tatcaaatga caaatacatc attctcaatt
    16321 gagcagtttt ctttaaaagg aaaaattgct ctcatcaccg gcgcttctta tggaattgga
    16381 tttgctattg ccaaatccta cgctgaagcc ggcgctacta ttgtctttaa cgatatcaat
    16441 caagatctgg tcaataaagg gattgaagct tatcgtgaag ttggcatcga agcccatgga
    16501 tatgtctgtg acgtgacaga cgaggacggt atccaagcca tggtcaagca aatcgaacaa
    16561 gaggttggtg tcattgacat cctcgttaat aacgctggta ttatccgccg agttccaatg
    16621 tgcgaaatga gcgccgctga tttccgtaag gtcatcgata ttgacttaaa cgcaccattt
    16681 atcgtttcaa aggcagttat tccttctatg ataaagaaag ggcatggaaa gattatcaat
    16741 atttgttcga tgatgagcga actgggacgt gaaacagtta gcgcttatgc tgctgctaaa
    16801 gggggcttga aaatgttgac ccgcaacatt gcgtctgaat acggtggagc caatatccaa
    16861 tgtaacggaa ttggaccggg ttatattgcc actcctcaaa cagcacctct tcgtgagttg
    16921 caagaagatg gttctcgcca cccatttgac cagttcatca ttgcaaaaac acctgctgca
    16981 cgttggggaa atcctgaaga tttgatgggc cctgctgtct ttctcgctag tgatgccagc
    17041 aattttgtca atggccacat cctatatgta gatggcggta tcttagccta catcggaaaa
    17101 caacctgagt aaaaatagaa agaagatctt atgaaaatcg cattaatcaa tgaaaatagt
    17161 caagctagca agaatcacat tatttacgat agtctaaaag aagcgacaga taaaaaagac
    17221 taccaattat ttaactatgg tatgcgtgga gaagaaggag aaagtcaatt aacttatgtg
    17281 cagaacggac taatggctgc catcctttta aatacaaagg cagttgactt tgttgttacc
    17341 ggctgtggta cgggtgtagg ggctatgctt gctttaaaca gcttccctgg tgttgtctgt
    17401 ggtctagcag tggacccaac tgacgcttac ctttattctc aaatcaatgg tggtaacgcc
    17461 ttgtctatcc cttatgccaa aggatttggc tggggggcag aactgaccct caaattgatg
    17521 tttgaacgct tatttgctga agaaatgggc ggtggctacc caagagaacg tgtaatccct
    17581 gaacaacgta acgctcgtat cttaaacgag gtgaaacaaa tcacccacaa tgatttgatg
    17641 accatcctta aaacaatcga ccaagacttc ctcaaagaca ccatctctgg caaatacttc
    17701 caagaatact tctttgaaaa ctgccaagat gatgaagtcg ctgcttattt gaaagaagta
    17761 ttagccaagt aaagctattc taaaccagaa aggaactaat ggatgacgaa aatattactg
    17821 tttggcgaac cattaattcg aatctcacca ttagatgcca ccagtatcgg cgatcatgtt
    17881 gccagttcga cttattttgg cggatcagaa attaacatcg cttgtaattt gcaagccctg
    17941 ggtatctcaa cgaaagtctt taccgcactc cctgccaacg agattggaga tcgttttctc
    18001 acattcttga aacagcacca aatcgatacc agttcaatct gtcggcttgg cgatcgaatc
    18061 ggcctctact atttggagaa cggctttggt tgtcgtcaaa gtgaagtttt ctacgatcgt
    18121 aagcatacga gtatcagcca gattcggcca aacatgctag atatggattc tctctttcag
    18181 gggattagcc attttcattt tagtggaatc accatagcta tcggtcaaga ggtccgtgcg
    18241 atccttctcc tactcttgga agaagccaag cgccgaggaa ttgtcgtttc aatggatctc
    18301 aatctgagaa caaagatgat ttcagtccta gaagccaagt atgaattttc taagtttgca
    18361 cgttttactg actattgctt cggtattgat cctctcatga ttgatgacca aaatctagag
    18421 atgtttccaa gagacagtgc tagcctagaa gaggtggaaa atcgcatgcg acttttaaaa
    18481 gaagcctatg gtttcaaggc cattttccat accctccgat ctagtgatga gcaagacaaa
    18541 aatgtctatc aagcctatgc tctggaagaa cgatttgaag agtctgtcca actaaaaact
    18601 gcagtctatc aacgaattgg tagcggggat gcctttatat ctggtgccct ttaccaacta
    18661 ctccatcatt cctccctaaa aactaccatt gactttgcag ttgcgagcgc aactctcaaa
    18721 tgcactcttc caggagacca tctctccact tccgcaacta gtattgaaaa tttactggca
    18781 aatgcacaag atatcattcg ttaggagaat tacatgacca aatcagatac gattattgaa
    18841 ctaaaaaaac agaaaattgt cgctgtcatt cgaggaaata caaaggaaga aggactacaa
    18901 gcctcgattg cttgtatcaa gggcggtatc aaagctattg aaatcgccta taccaatcag
    18961 tatgcaggac aaatcatcaa ggaacttgta gacttgtatc aggacgatca gagtgtttgt
    19021 atcggtgcag gtactgtgct tgatgccgta actgctagag atgccattct agctggagca
    19081 aattacgttg tttctccatc tttccatgct gaaactgcga aaatgtgcaa tctctacagc
    19141 acaccgtaca ttccaggctg tattaccctc acagagatca cgactgcact tgaagccggt
    19201 agtgaaatca tcaaactctt cccaggtagt actctcagtc cagcatatat ctctgcagtc
    19261 aaggcaccga tcccacaagt ttccgtaatg gtaaccggag gagtcggcct aaacaacatc
    19321 cctcaatggt tcgctgctgg tgcagatgcc gttggaattg gtggcgaact caataaactc
    19381 gcttcccaag gcaactttga ccgcatcagc gagattgccc aacagtatat tacactcaga
    19441 taaaatcata actacccgtc taacgggtgg tttatctcag agctataagc ccaaatcatc
    19501 agccagcgcc taaagacgct ggctttcacg ttgttcaagc cttattgctc ttgactcgtc
    19561 acttgcctct ttaagagact ttggtattac ttaccactat ccctaaaggg atcctcatat
    19621 tcttttacac tcaatttatc tagtgctata gtagattgaa actggaatag tatacctcta
    19681 cttctaaaac attgttaaaa atcgatttga ctgtcctgat cgattttgtc ctgttcttat
    19741 ttcattttac tatatatcat actttactag ttctcaaatt ttcatactcg tgaagaaatc
    19801 atccactcga taatttcttt aatcttgact atatttctta attgtggctt cattaagccc
    19861 tactggactt acataataac cttccgccca gaaattccga ttcccaaact tgtacttgag
    19921 attggcgtgt ttgtcaaaca tcatgagtgc acttttgcct tttaaatacc ccataaaact
    19981 tgaaacactt agcctcgacg gaatactgac taacatgtgt acatggtctg gcattaagtg
    20041 accctcgatc atttcaacac ctttataact acacaagcga tgaaatattt cgcctaaact
    20101 acttctatat tgattataga tgacttttcg tctatactta ggggtgaaca caatatgata
    20161 gaacacatcc actttgtgta tgataaacta tgagtctttt gtgccatatt ttttctcctt
    20221 tcgctttaca attggattga atacctttat tgtatcgcgt ttggagtttt tttggtataa
    20281 ccttcgacgc gcacctcacg gagcgagacg gacttatata gtggagtgaa ataggatacg
    20341 aacaaattga ttaggaaaat caaatgaatt tatagaaatc ttttagcagt tataacgttc
    20401 tattctagtt tcaaaacgct atagtcacat aataatgaag taaaaaagga taagtatcaa
    20461 cttatccttt tttaaaagaa aaatccgaag atatttggcc ttcttcggat tttttctatt
    20521 ttccacagtt tcatgtaatt catctagatg atgaacaaat tagttgttct ttcctctacg
    20581 gaatagataa aatgccccaa gtagcaagaa ccctagactt gccaagattg actgaccttc
    20641 tcctgtctga gggagattct tttgatccga atggttcttt tcctcttcag atttttcctt
    20701 ttcttttgaa ttctgtactt gtggctgagc tgcttgctct agctttttaa agacttcctg
    20761 atctggagct gattcctggg tttcaggatt atagtaggca atcttatatt catccccttc
    20821 ttttcgaatg gtatagactc cacgtttcaa aacttggaat tggttggaaa tagtagagac
    20881 agaatcatca tatttcacaa tgccccaaac tccttgttta gcatcataaa cagactgaag
    20941 ggtttcgcta ttttcgatga ggctactttc taactctttt atcatttgat tgaaggtggc
    21001 acgatccacg ttaggaatta gcatatagcc ataagaatct ccattttgct tatgagcctg
    21061 actaatcgta agaaattcat tttcaacttc cttgtctgac tgtccttcat tgatatcctt
    21121 ccaggctccc ttttgcaaag ccttactcat actgattgaa ctcttcttaa agaaaaagta
    21181 accaatattc tttttcgaat cggacgattc taaaaagaca ctttgggttt caggataatc
    21241 cttttcttgt tctgtaaggg aggcttcttt atcattgaca tagactttat atggattact
    21301 tgattccagt tggtgaaatc catggttgct gtcgcattgg catcatctag tttgctcgtt
    21361 ccaacgaaag cagacggtag aactttacct gtatcgctat ccgctctctt agcatccgtc
    21421 tctgttgtac caggcatctt atatggatta actgttggcc agtagccatc gctatagtga
    21481 ctcaaatcgc cattgtaaag atagaacatc ccatcactcg tataccaacc atgtttattt
    21541 tccttgttca tgtgttcgta attcaaggta cgactggaaa agagtgacaa gccaaatcca
    21601 aaccctttct ctgcattgta catggctgtt ttatccatct tgttaaaggc agataggtaa
    21661 cttgttcttg gaacacttgc gactcctgca tcacttaaca aggattgcat caaactgata
    21721 tccttataag tcttcaaatt cttaaagaca tcataataac tatccgattg aacaatggtc
    21781 ttcacaagac tctgcaaacg ttgtttggtt tctccttcag acatatccgc tattcggtga
    21841 atccctctta gtacttctac tgcggccacg tgcccctcgc tatttgcacg actgatcgag
    21901 cgtccacgac tcatatccat cagctctcca ttcaccagca aaggagcaaa cgatttatca
    21961 atccagtggt acatggtttg cattttatct ttatcgattg gattcttggt cttttgaatg
    22021 actggcaaca gttgagacag gccatcaatc aaaacattcc cataagcacc cgtataggca
    22081 acattggtat ggtcgatata ggatccatct tgataaaaac cttcaccttg gtctaccaac
    22141 ttgaacactt gctcaatcga gcgaatggta gaagaaattt cttgatcatc cttacgcagt
    22201 aaaccagcta ttacttttac tcttcccata tcaactaagt ttccacctag agccttaaat
    22261 gggttatcag tcgtctttcg gaaatgttcg ggatctggta caaatttttc aatcacatct
    22321 gtatattttt taatttcctc atcagagaag tattctttca tcagagacaa ggtattgttg
    22381 atggcacgag gtgtaccgat ttcataatcc caccagttcc caacaatgct cttttcacta
    22441 ttgtagacat gtttatgcat ccattccatg gaatccctga ctgttcgaac gacagtttca
    22501 tcttgataat aacgagaaga aggattggtc acttgcttgg ccatctcctc caatttccga
    22561 taagtggcag tcagatttgc agacatttta taatttgaaa atttttccca caaataggtg
    22621 cggtccgcct gacttgaaat actagatagg ctatcagcta cctttccttc caattcctgg
    22681 tttaatttgg ccatctgttc atttttagaa tcatagtatt gattcccagc aatgatgcca
    22741 ttccagtcat ccaaacggtc tgtgtatgca tccttaacag aggctagaat cttcaaagga
    22801 atctttttca cttccttgcc atctttactg acaatgacat tggttgtccc ttccttaaga
    22861 ggttctaaaa ttccattttt gactgaagca acgtcaggat tttctacctt ataagtatag
    22921 tccgcaagag aaaaaacatg tttttttcca attggtaaat caatcttttc ctcaagctgt
    22981 ttatctgttt gagaatcctc agaaagctgg gctgctacct ctaccagctc aatatcctta
    23041 aaggaaacag tcccagttcc tgtttcatag aataactcca gcttgatttt atcaacatct
    23101 aaagtcgggc tatagtctgc ttcaatggtc tgccagtcct ttgttcctga cgtcgttgca
    23161 gaattccaca atcgcttgtc cttaccactt tcctcaatga tacgaacttt ggcaatcccg
    23221 actttatgat ctgttttaat cttgaaacgc agtttatact ttttcttagc ttcaatagga
    23281 accatacggt gaaccgctgc ccttaatttc tcagggcttg agatagtgat agccccatcc
    23341 ttagcctcaa tgactcgagt tgaggcatct gcagaactat tcttctggtc tacccaagct
    23401 gaccacccct gagctttgct tcctgtccac ggactgcttc cgtcctccgt ctgaccaaaa
    23461 tcaccatttt caactaaatt ttttgtatcc ctttgctgat actgaacttc cttctggctt
    23521 tgctgaatgg tattcgtagt cgtttcttcc gctccaactg tcatataatg gtttaataaa
    23581 aatcctgata aaacaagtga agacaaactc acaatgagct tctttgtttt tgtttgcatg
    23641 tatacactcc aataaacata ttgtaaaatc aataggaact aaatctcaaa ttagagattt
    23701 atagcaacta agtaaaccgg tttaattaaa ttataccatt tttaaagtta tttgtaaacg
    23761 gtttctatca tattgagggc ttattcttca acaatatctt ccatccgact cgacgaaaaa
    23821 agtaaaaact gttacaatgt agaaaaagaa aagaggccct catgacttca ctttatgatt
    23881 tttccgtttt gaaccaaaac aaccaagcaa ctcccttgga tagctatcgt ggcaaagttc
    23941 tcttgattgt caacactgct actggatgtg gtttaacgcc ccagtaccag ggacttcaag
    24001 aactctatga acgctatcaa gatcagggct ttgaaatatt ggatttccct tgcaatcagt
    24061 ttatgggaca agcacccggc agcgcagagg aaatcaacgc cttctgtagc ctacattttc
    24121 aaaccacctt cccacgtttt gccaagatta aggtcaacgg taaggaagca gaccctctct
    24181 atgtctggtt aaaagaccag aaatccggcc cactaggaaa acgagtcgaa tggaatttcg
    24241 ctaagtttct catcggtcga gatgggcaag tctttgaacg cttttcttca aaaacagacc
    24301 caaaacaaat tgaagaggcg atacaaactc tactataatt cacaatctca ctatgattag
    24361 gtttccttta acctgatgaa tagtgagatt ttttgattgg ctttgactta aatagaaaaa
    24421 caccccatga tatgaaacat gaagtgttgt aaagtggttc tataatattt gtagtgggta
    24481 aatccactat agatattatg gagcctattt tattgtagaa aaaaagtccc atatgaccta
    24541 taatgaaaag cgacaaaaca actcattaga aagattcata tggaacaatt acattttatc
    24601 acaaaattac tagacattaa agaccctaat atccagattt tagacatcat caagaaggat
    24661 acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc tgagtgcgga
    24721 aaccaattga agaaatatga ctttcaaaaa ccttctaaaa ttccttatct tgaaacgact
    24781 ggtatgccta ctagaattct ccttagaaag cgtcgattca agtgctatca ctgttcaaaa
    24841 atgatggtcg ctgaaacttc tatcgtcaag aagaatcacc aaatccctcg tatcatcaac
    24901 caaaagattg ctcaaaagtt aattgaaaag atttctatga ctgatattgc ccatcagctt
    24961 tccatctcaa cttcaactgt tattcgtaag ctcaatgact ttcactttaa acatgatttt
    25021 tcttgtcttc ctgagattat gtcttgggat gagtatgctt ttacaaaagg aaagatgagc
    25081 ttcattgcgc aagattttaa caatctcaat atcatcactg ttcttaaggg aagaacacaa
    25141 gctgtcatcc gaaatcactt tcttaaatat gatagagccg tccgatgtcg cgtcaaaatc
    25201 attactatgg atatgtttag tccttactat gatttagcta gacaactttt cccgtgtgct
    25261 aaaatcgtgt tggatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg
    25321 cgtgttcaaa tcatgaatca gtttcatcga aaatcccatg aatacaaggc tatcaagcgc
    25381 tactggaagc tcatacaaca ggatagccgt aaactgagtg ataagcgatt ttatcgtcct
    25441 acttttcgta tgcacttaac caataaagag attttagaca agcttttgag ctattcacaa
    25501 gacttgaaac accactatca gctctatcaa ctcttgctgt ttcactttca gaataagaaa
    25561 ccggagaaat ttttcggact cattgaggac aatctaaagc aggttcatcc tatttttcag
    25621 actg
//
LOCUS       DAVLHM010000029        24925 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLHM010000029 DAVLHM010000000
VERSION     DAVLHM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.029"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..221
                     /locus_tag="VXE45_001365"
     CDS             <1..221
                     /locus_tag="VXE45_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789387.1"
                     /translation="IFNFRDKELIFFNKIVNGLIQNIEENLEDDIERILKYLYICLFN
                     EIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            233..982
                     /locus_tag="VXE45_001366"
     CDS             233..982
                     /locus_tag="VXE45_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0789388.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            995..2167
                     /locus_tag="VXE45_001367"
     CDS             995..2167
                     /locus_tag="VXE45_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0789389.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIAIPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     FFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFEFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            2562..3425
                     /locus_tag="VXE45_001368"
     CDS             2562..3425
                     /locus_tag="VXE45_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0789390.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRLQQYKKLID"
     gene            3711..3908
                     /locus_tag="VXE45_001369"
     CDS             3711..3908
                     /locus_tag="VXE45_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0789391.1"
                     /translation="MLNLQFAETMELTEAELETGYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            3976..4641
                     /locus_tag="VXE45_001370"
     CDS             3976..4641
                     /locus_tag="VXE45_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0789392.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            4713..5939
                     /locus_tag="VXE45_001371"
     CDS             4713..5939
                     /locus_tag="VXE45_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0789393.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLT
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(6289..6366)
                     /locus_tag="VXE45_001372"
                     /pseudo
     CDS             complement(6289..6366)
                     /locus_tag="VXE45_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            6437..7093
                     /locus_tag="VXE45_001373"
     CDS             6437..7093
                     /locus_tag="VXE45_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0789394.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTLVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            7083..7406
                     /locus_tag="VXE45_001374"
     CDS             7083..7406
                     /locus_tag="VXE45_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0789395.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            7509..8339
                     /locus_tag="VXE45_001375"
     CDS             7509..8339
                     /locus_tag="VXE45_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0789396.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            8493..9347
                     /locus_tag="VXE45_001376"
     CDS             8493..9347
                     /locus_tag="VXE45_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0789397.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            9447..10820
                     /locus_tag="VXE45_001377"
     CDS             9447..10820
                     /locus_tag="VXE45_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0789398.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            10813..11874
                     /locus_tag="VXE45_001378"
     CDS             10813..11874
                     /locus_tag="VXE45_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0789399.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            11876..12568
                     /locus_tag="VXE45_001379"
     CDS             11876..12568
                     /locus_tag="VXE45_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789400.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(12597..13166)
                     /locus_tag="VXE45_001380"
     CDS             complement(12597..13166)
                     /locus_tag="VXE45_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0789401.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            13301..13915
                     /locus_tag="VXE45_001381"
     CDS             13301..13915
                     /locus_tag="VXE45_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0789402.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            13917..15563
                     /locus_tag="VXE45_001382"
     CDS             13917..15563
                     /locus_tag="VXE45_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0789403.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            15575..16861
                     /locus_tag="VXE45_001383"
     CDS             15575..16861
                     /locus_tag="VXE45_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0789404.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            16913..17446
                     /locus_tag="VXE45_001384"
     CDS             16913..17446
                     /locus_tag="VXE45_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789405.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            17524..17994
                     /gene="nrdI"
                     /locus_tag="VXE45_001385"
     CDS             17524..17994
                     /gene="nrdI"
                     /locus_tag="VXE45_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0789406.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(18287..19549)
                     /locus_tag="VXE45_001386"
     CDS             complement(18287..19549)
                     /locus_tag="VXE45_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0789407.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(19859..20317)
                     /locus_tag="VXE45_001387"
     CDS             complement(19859..20317)
                     /locus_tag="VXE45_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0789408.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(20314..20754)
                     /locus_tag="VXE45_001388"
     CDS             complement(20314..20754)
                     /locus_tag="VXE45_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0789409.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            21187..22053
                     /locus_tag="VXE45_001389"
     CDS             21187..22053
                     /locus_tag="VXE45_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789410.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            22390..22947
                     /locus_tag="VXE45_001390"
     CDS             22390..22947
                     /locus_tag="VXE45_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HEV0789411.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            23168..24274
                     /locus_tag="VXE45_001391"
     CDS             23168..24274
                     /locus_tag="VXE45_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEV0789412.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            24250..>24925
                     /locus_tag="VXE45_001392"
     CDS             24250..>24925
                     /locus_tag="VXE45_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789413.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEY"
BASE COUNT         7703 a         4176 c         5265 g         7781 t
ORIGIN      
        1 aaatatttaa ttttagagat aaagagctta tcttttttaa taagattgta aatgggctga
       61 tacaaaatat tgaggagaat ttagaggatg atattgaaag gatattgaaa tatttatata
      121 tatgtttatt taacgaaata ttcattatta agaataaggt gaattttttt gatgatgtgg
      181 aatttaatca gacacttagt gagtttttag ataaattgta gagggaatgg ttatgagtaa
      241 caatactaag tatatctttt tatctccaca tttagatgac gcaatttttt cctgtggtga
      301 ttatatttca aaattaactt cagaaggaga aattgtactt gttattacta tattttctgg
      361 ttaccctttg agccaacagc tacagccctc tgctaagcaa tttcataagt tgtgtaacct
      421 tgggaaatat ccgattgaag aaaggaagaa agaagacagg ttagcttgtg aacgtctaca
      481 atgtgatttt agacacttat cgtactatga atgtctctat aggaaagata gaaatggcaa
      541 ttttctatac cgtcatatct atagtgaatt aaaaaatgag gacacattaa agaatgatat
      601 cataaaagag ctgttaatgc atttagacga taaatgtgtc gtatattgtc cgctttcact
      661 tggtgaccat gttgatcatg tttttgtgaa tagtattgga agggcgcttg aatttatgcg
      721 ttataaagta atatattatg aggacttccc atatgtaagt gatagtagta tggttagtta
      781 tatgggaaaa actaaagaat taaaaatgta tcaagaggaa cttgatgaaa aacattatat
      841 tgatagaata tcatcaatat tgtgctataa atctcagatt ttgataatct ggaaatcagt
      901 tgaaaaactt ttaaacaata ttaaagagtt gtatttaagg aatggggcag cttattctat
      961 tagattttgg attaagaaat aaggaagtag ttttatgaat atagcagtaa ttggtttggg
     1021 gcatgttggg ctggcctacg cgttactatt tgcatctaaa tataaagttg ttgcatatga
     1081 tatagattct gtaaaaataa ataatttaaa aaagggcatt cttccatcta aaaatgaaga
     1141 gcttatgaag tttttttgcg agaataactt aaatattact ttttttgata cattttctga
     1201 aattaaaaat aatattgatt attatattat tgcgattccg acagattatg atgagaaaat
     1261 tggtagtttt aatacatatg aaatcgaaca aacggtatcg aagattctga gggtaaaacc
     1321 taatggaaag attattttaa agtcaacagt tccgatcggc ttttcaaaca aattaaaaag
     1381 gctgtttgat acaaaaaata tcatttttgt ccctgaattt ttgagagaag gttgttctat
     1441 atatgataat ttatatccaa gtcgcatagt tgttggagat gagacagttg aaggaagaaa
     1501 aattgcagag ttgttccttt cgattagtac tcatagtact gccaatatta aaaatgttat
     1561 gttagtttct cctactgaag cagaagcaat taagcttttt tctaacacat tcttagctct
     1621 ccgtgttgct ttttttaatg aactagattt ttttgctgag aggagaagtt taaatgctga
     1681 agttgtaata aaaggtgttt gtttagatcc aagaattgga aatttttata ataatccttc
     1741 ttttgaattt ggaggatatt gtcttcccaa agatactaaa caattaaaaa aagaatttat
     1801 agaaataaat gccccagtga tagaagcgat tgatatttca aacacaaata gaaaacagtt
     1861 catagttaaa caaatattgg aacgaaagcc aaagatagta ggaatatata aattggggat
     1921 gaaatataat tcagataatt acaaagagtc agctatttta agtataatta atgaactatt
     1981 gattgtcggt ataaaaattt tagtatatga accaaattta aacgttagta tagataacgt
     2041 aatttttgaa aagaattttg aactatttac aaaacaaagt gatctaattg ttgcaaatag
     2101 atgggatagg ggccttgaag cttataaaga taaagtttac acaaggggga tctggataag
     2161 agattaacta ttgatattaa aaaggcaata atttataaaa tttgtacaaa aaaatgttaa
     2221 attttcacat tttcatagta tactgtttaa tagaaagtag gttctttgta accgctccat
     2281 tataaaatcc tttcactctt ccggtatgct attaggaaaa acataattgg aggatatttt
     2341 gagctcacac ctcatcgttc cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt
     2401 tagacattct atttagaacg aggattgagt tctgtattgt acaaggctcg gtccttttag
     2461 agtcagctta aggctggctt tttcaatcac caaagtgtca gaatgttttg acaaatgaac
     2521 acaaataatg atataatatg caaaagctag gaggtggtag gatgattgaa aaaatggaac
     2581 tgggggaatt ttacaaggaa ttacgtttgg cgagaaagct caagcagtca gatgtggctt
     2641 gtgacgggct aacagcttct cagttgtcca agtttgagct agggcagtcc atgttgtctg
     2701 ctgataagct catattagcc atccaaggga tcaatgtgac ctttgatgag tttgggcaca
     2761 agctcaacaa ctatcaagaa tctccacata tgcagattgg tagaaaggtt gtggatcgct
     2821 ttgctcatca agatatagct ggcttagagc aactgttgga ggaagtcgag caagaacaga
     2881 tggcagagac ttatcgtcgt ttgaatgcta ttgtaatcaa agatgccatc cactcactag
     2941 ataaaagcta cccactagca gaggaggata gcgagttttt gaccacctat ctctatgcta
     3001 tcgagtcttg gacctggttt gaactctatc tcttttgcaa tactctgccc ttcttgagca
     3061 atcaagatct gatcttttta tcaacctcct tactcgaaaa atccaaagaa tttaaagagt
     3121 tagtacacaa tcgattgtat atgaagcaag gactcttaaa tatcttatca gaactcatgg
     3181 agcgaaaact tttcttatac atcccaatct tcgaagccga gttggagagc atgttgcgtc
     3241 cgtacgatgt ttttgaaaaa gtatcgtggc aatttttaaa gaagatgagt gtctttcttc
     3301 aaacaaaggg aagcaatcaa aaagagattg aacgctttac ccaatctctg caggtattag
     3361 aaaatccaca attaacatcc ctttttgaat tgcgtttgca gcaatacaaa aagcttatcg
     3421 attagttaga aatggcaaaa taataataat ctcagcaacg atcgtcaata atgttaaaac
     3481 ttgtttcttc atattacttc cctcctcatt agtaataact ttattatacc agggaaataa
     3541 tcaaatctac caaaatcgca aatctgaaat ttctataaga aaaaatatca aatatgcgat
     3601 tttctaaaat aagccaattt ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc
     3661 taggtcgcag aagtggttta caaatgaaga taattgaagg agtgtaaaag atgttaaatt
     3721 tacaatttgc agaaacaatg gaattgacag aagctgagtt ggagacaggt tatggagggg
     3781 aatttgggaa taatgctgtt atcccagccg gtgcttgggg aggtttagga acgtcttggt
     3841 caatcactaa tttctggaag aaatatttta accatgattc ttccactgtt aatcgtcgcc
     3901 attattgata ttcagagtcc ttgccttttt cttgggtagg gactgtcttt atttcatagt
     3961 ataggagaaa atagaatgaa aaagataatc tcacaccgct actttattat agtttttcta
     4021 ctagttattg ctgaccagaa gttcagtgtt ttagttttac gcagcgacct tgttgctggg
     4081 ctatctgact ttgcctatta tctgtcggat atgatgttga attttcttgt ggttttattt
     4141 gctcttattg ctatgatttg gtcggggaaa tggcagaaaa tcaatagtag aaagtttaaa
     4201 ggatcctatc ttttctattc cttcctagct ctgcttgctt ttgttgcttg gaattttgtc
     4261 accttttttc ttttcccacc tactcgaaat gaaatttctt atcaacatgc tgctcctact
     4321 tttacaggag ctacggcatt tttgatgtat tttttttatc ctgtgattgc aggtcccatt
     4381 tttgaagaca tgatttatcg tggattagtg atgactgctc tggaaaaagg aaagaaatgg
     4441 gggctagatg tacttggttc cgctgtttta tttggggtct cgcacattag taatcacggt
     4501 tgggtcttga cagactttgt cttctatatg ggtggaggtc ttatatttgc agtcttattt
     4561 agaatgacaa agtcaattta ttggcctatt ggactgcata tagtctacaa tggcattggt
     4621 cagcttttga tgttactgta attttggttg ttagtagtat cgcggtctat ccttggggaa
     4681 agattcccat ttgaacttaa gaaggagttg tgatgaaagt atttcttcaa aatagagatt
     4741 ttaggcaatt aactatcaac cagtggattt caacgcttgg ggatacgatt ttttatctgg
     4801 cctttctgaa ttatgtggca gatgcgtctt ttgcaccttt gacgatttta ctcattacga
     4861 tttcagaaac ccttccccaa attttacaaa tctttctggg agttttggca gattttcaac
     4921 atcatcgtgt cttgaaatac acagtcatta gttttgcaaa atttttgctt tactctatcg
     4981 tttctttatc actttcaggg cagtctttct ccttgttgct agtagcattt atttgtctgc
     5041 ttaacctctt gtctgacaca ttgagttact tttcaggagc catgctcact ccgattttca
     5101 ttagaattat tgggcaagac catctggcag aagctattgg ctttaaacag tcaactgtta
     5161 gtttagtgaa aacaatcagt aatatcctag gaggagtctt actaggcatt ctatccatcc
     5221 agtttatttc cttactgaac gctcttacct ttttaatcgc atttttaggt atcctcttca
     5281 taaaaactga cctcttgaaa gtagaaaaaa cgattagcta tcaagaagga ctctctgtaa
     5341 aatccttttg ccagcatttg ctccaatcat caaaattgat atggaatatg aataaggtgc
     5401 tcttggtttt gtttattatc tctactagtc aagcagtgat aaatgttacg gttcctattt
     5461 ccactctatt tttaaggaac cagccctttt tgaatttaca aacaggtcaa tctcttgcct
     5521 tgctatccac ttttgaactg tcagccctga ttgtcggaag ccttgtaagt ggctatctgc
     5581 aacataccat ttccataaaa acagctctct atgcctcact tgtcatccag ttgcttcttc
     5641 tagtaggatt tgccacagtt cgttttgact ggattctcat ctttagtacc ttggatgcct
     5701 ttttcgcagg tgttctctct cctagattgc aagaactcgt ttttaaacaa atacctgagg
     5761 agtcaatggg agcagttcaa tcctctatcg gtgccattac ggttgtttta cctagcttat
     5821 ttacaatagc tttggtaacc attgctacta gctttggaac tctggcagtt agctttgttt
     5881 tattgctatt tcttctagtt gcctttgtta tgcttctgaa tattcgtgaa agtatttagt
     5941 ggagaatttc tataatatat gtttgagact ggattgccag tctttttatg atggtcaaaa
     6001 tcaacagact ttttctcttt tctgaatgtg ttatagtaga ctgaatctaa aatagtacga
     6061 aacaattgct aaaacattta tagaaattaa ttttactttc ccaatcgatt tgttctcatc
     6121 ttatttcaat ctgctatata atagtccatg ctgtggctgg attcttttca gcctacttgt
     6181 actcttcgaa actctcttca aaccacgtca gcttcacttt gccgtagtac ggttactgac
     6241 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc
     6301 cacaacctca aaacggtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat
     6361 tttcattgag tattattaag acaatatgag gagaaagatg aaagaaaaag gattttagga
     6421 gggggcgcag gcagccatgc caacggctct tggctatgtc agtatcggcc tggcctgtgg
     6481 aattatcggt gcgccctatg tgacacttgt tgagatgggc ttgatgagtc tctttgttta
     6541 tgctgggagt gcccagtttg ccatgttggc actgattgtg gttcaagctc ctgtggcagc
     6601 tattgctatg acggtttttc taatcaactt gcgtctcttt ttgttgagtt tacacgcatc
     6661 gacttatttc cgtcatacca gtctttggta caatatcggt atgtctagta tcttgacaga
     6721 tgagacctat ggcgttttga tgggtgaatt ggcccataca gacaaggtaa atcctatgtg
     6781 gatgcacggg aacaatctca acagctatgt ggcttggttt gtggggacag tagtcggaac
     6841 ggctctgggt ggcctgctac caaatccaga aatctttggc ttggattttg ccctggttgg
     6901 gatgtttatt ggtatttttg cttcgcaatt tcagattatg caaagacgga ttcctgtccg
     6961 caatctgctc attatcctag cagttgttgc ggtgtccttc tttttgctct tgacagtggt
     7021 gtctcagtca ctagctgttc tgtttgcgac gctacttggt tgtagcatgg gggtggtttt
     7081 agatggtcag taagtatctt ttattagcag ttattttctc tggtcttgtg acctggattc
     7141 cccgtatgat tcccttcatc ttggtcaagc ataagggcct gcctgcgatt gttgagcgtt
     7201 ttttgaagtt tttgcctgtt tccattatct ttgccttgat tctttcaagc gtagtgacag
     7261 gtaaggttgg gagccttcct caaattaaat ggctagactt cttagccgtc tttccaacag
     7321 cttgggtagc ctttcgctac cgcaatctag tcggaacagt tctctttgga gtggtcttga
     7381 ttgccatctt gcgtttggtc ttttaaatta cccataaaaa aacttatcac agagatagat
     7441 atcatataat ggcgtaaatg ctctttttct gttaagatta taaggtattc tattttggag
     7501 gaaatgacat gaaaaaaatc gttaaatact catctcttgc agcccttgct cttgttgctg
     7561 caggtgtgct tgcggcttgc tcaggtggtg ctaagaaaga aggacaagca gctagcaaga
     7621 aagaaatcat cgttgcaacc aatggatcac caaagccatt tatctatgaa gaaaatggcg
     7681 aattgactgg ttatgagatt gaagtcgttc gcgctatctt taaagattct gacaaatata
     7741 atgtcaagtt tgaaaagaca gaatggtcag gtgtctttgc tggtcttgat gctgaccgtt
     7801 acaatatggc tgtcaacaat cttagctaca ctaaagaacg tgcggagaaa tacctctatg
     7861 ccgcaccaat tgcccaaaat cctaatgtcc ttgtagtgaa gaaagatgac tctagtatca
     7921 agtctctcga tgatatcggt ggaaaatcga cggaagtcgt tcaagccact acatcagcta
     7981 agcagttaga agcatacaac gctgaacaca cggacaaccc aactatcctt aactatacta
     8041 aggcagattt ccaacaaatc atggtacgtt tgagcgatgg acaatttgac tacaagattt
     8101 ttgataaaat cggtgttgaa acagtgatca agaaccaagg tttggacaac ttgaaagtta
     8161 tcgaacttcc aagcgaccaa caaccgtacg tttacccact tcttgctcag ggtcaagatg
     8221 agttgaaatc atttgtagac aaacgcatta aagaactcta caaagacgga acgcttgaaa
     8281 aattgtctaa acaattcttc ggagacactt atctaccggc agaagctgat attaaataat
     8341 ttcttgaaat catccattct gagtaagatg ggtggtttct cagtttttag ggatatagtt
     8401 ttaaactata tatctgacta tctaataaca atttgtgaaa tcaaacaaat tgtgagatac
     8461 tagtacggta ttatttttaa ggagaaagaa tcatgaaaat caaaaaatgg cttggcctag
     8521 cagcccttgc tacagtcgca ggtttggctc ttgcagcttg cggaaactca gaaaagaaag
     8581 cagacaatgc aacaactatc aaaatcgcaa ctgttaaccg tagcggttct gaagaaaaac
     8641 gttgggacaa aatccaagaa ttggttaaaa aagacggaat taccttggaa tttacagagt
     8701 tcacagacta ctcacaacca aacaaagcaa ctgctgatgg cgaagtagat ttgaacgctt
     8761 tccaacacta taacttcttg aacaactgga acaaagaaaa cggaaaagac cttgtagcga
     8821 ttgcagatac ttacatctct ccaatccgcc tttactcagg tttgaatgga agtgccaaca
     8881 agtacactaa agtagaagac atcccagcaa acggagaaat cgctgtaccg aatgacgcta
     8941 caaacgaaag ccgtgcgctt tacttgcttc aatcagctgg cttgattaaa ttggatgttt
     9001 ctggaactgc tcttgcaaca gttgccaaca tcaaagaaaa tccaaagaac ttgaaaatca
     9061 ctgaattgga cgctagccaa acagctcgtt cattgtcatc agttgacgct gccgttgtaa
     9121 acaatacctt cgttacagaa gcaaaattgg actacaagaa agcacttttc aaagaacaag
     9181 ctgatgaaaa ctcaaaacaa tggtacaaca tcattgttgc gaaaaaagat tgggaaacat
     9241 cacctaaggc tgatgctatc aagaaagtaa tcgcagctta ccacacagat gacgtgaaaa
     9301 aagttatcga agaatcatca gatggtttgg atcaaccagt ttggtaataa gaaacaggga
     9361 ggtgggagag aaaattccac ctcttgcttt tgtatagagt atagattgta aagaagacta
     9421 ttcgttcata gaaaggtaga gagaatatgg tttttcctag cgaacaagaa cagattgaaa
     9481 aatttgaaaa ggatcatgta gtccaacatt attttgaggt tttgcgtacc ttgatttcta
     9541 agaaatcagt ctttgcccag caggttggac tcaaggaagt cgcaaattat ctgggtgaga
     9601 ttttcaagcg tgttggagct gaagtggaga ttgatgagag ctatacagcg ccctttgtca
     9661 tggcacattt caagagttcg cgtccagatg ccaagacctt gattttctat aaccactatg
     9721 acactgtgcc agcggatggg gatcaggtct ggacagagga tccttttacg ctttcggtcc
     9781 gcaatggctt catgtatggg cgtggggttg atgacgacaa gggtcatatc acagctcgct
     9841 tgagtgcttt gagaaaatat atgcagcacc atgatgattt acctgtcaat atcagcttta
     9901 tcatggaggg agcggaggaa tcggcttcaa cagacctaga taagtatttg gaaaagcatg
     9961 cagacaaact ccgtggggcg gatttgttgg tctgggaaca agggaccaaa aatgccttgg
    10021 aacagctgga aatttctggt ggcaataagg ggattgtgac ctttgatgcc aaggtaaaaa
    10081 gcgctgatgt ggatatccac tcgagttatg gtggtgttgt ggaatcagct ccttggtatc
    10141 tcctccaagc cttacagtct cttcgtgctg cggatggccg tatcttggtt gaaggcttgt
    10201 acgaagaagt acaagagccc aatgaacgag aaatggcctt gctagaaact tatggtcaac
    10261 gaaacccaga ggaagttagt cggatttatg gattggagtt gcctctctta caggaggagc
    10321 ggatggcctt tctaaaacgt ttctttttcg agccagcgct taatatcgaa ggaatccagt
    10381 ctggttatca aggtcagggt gttaagacta ttttacctgc agaagccagt gccaagctag
    10441 aggttcgtct ggttccgggc ctagaaccgc atgatgttct ggaaaaaatt cggaaacagc
    10501 tagacaaaaa tggctttgat aaggtagaat tatactatac cttgggagag atgagctatc
    10561 gaagcgatat gagcgcacca gccattctca atgtgatcga gttggccaag aaattctatc
    10621 cacagggcgt ttcagtcttg ccgacgacag cggggacagg acctatgcat acggtctttg
    10681 atgccctaga ggtaccaatg gttgcattcg gtctaggaaa tgccaatagc cgagaccacg
    10741 gtggagatga aaatgtgcga atcgctgatt attacaccca tatcgaatta gtagaggagc
    10801 tgattagaag ctatgagtag agatattatc aagttagatc agatcgatgt gacttttcac
    10861 caaaagaaga gaaccattac agcggttaag gatgtgacca ttcacatcca agaaggggat
    10921 atctacggaa tcgttggata ttctggagca ggaaaatcaa cccttgtacg ggtgattaat
    10981 ctcttgcaaa aaccatctgc agggaaaatt accattgacg acgatgtgat ttttgacggc
    11041 aaggtgacct tgacggcaga gcagttgcgt cgtaaacgtc aagatatcgg aatgattttc
    11101 cagcatttta acctgatgag ccaaaagaca gcagaggaga atgtagcctt tgcccttaaa
    11161 cactctgaac tcagcaagga agaaaagaag gctaaagtag ctaagttgtt ggacttggtt
    11221 ggtttggcag atcgtgctga aaactaccct tcacaactat ctggagggca aaaacagcgt
    11281 gtggcaattg cgcgtgcctt ggccaatgat ccaaaaatct tgatttcaga cgagtcaact
    11341 tctgcccttg atccgaagac aaccaagcag attttggcct tgttgcaaga tttgaaccaa
    11401 aaattaggct tgactgttgt cttgattacg catgaaatgc agattgtcaa agacattgcc
    11461 aaccgtgtgg cggttatgca ggatgggcat ttgattgaag agggtagtgt gcttgaaatc
    11521 ttctcagacc ctaaacaacc tttgactcaa gactttatct caacagccac aggtattgac
    11581 gaagccatgg tcaaaatcga gaagcaagaa atcgtggaac acttgtctga aaacagtctc
    11641 ttggtgcaac tcaagtacgc tggatcttca acagacgagc cacttttgaa tgaattgtac
    11701 aagcattatc aagtaatggc taatattctc tatgggaata tcgaaatcct cgatggtact
    11761 cctgttggag aattggtggt ggtcttgtca ggtgaaaaag cagcgttggc aggtgcccaa
    11821 gaagccattc gtcaagcagg cgtacagtta aaagtattga agggaggaca gtaagatgga
    11881 atcattgatt caaacctatt tgccaaatgt ctataagatg ggttggtctg gtcaggcagg
    11941 ctggggaaca gctatctacc taaccctcta tatgacagtt ctttccttca ttatcggagg
    12001 cttcttgggg ctagtggcag gtctctttct cgtcttgaca gcgccaggtg gtgtcttgga
    12061 gaataaagtc gtattctgga ttttagacaa aattacctca atttttcgtg cgattccctt
    12121 tatcatcctc ttggcaatct tgtcaccact ttctcacttg attgttaaaa caagtatcgg
    12181 gccaaatgca gcccttgtcc cactttcttt tgcagtcttt gccttctttg cccgtcaggt
    12241 gcaggttgtc ttggctgaat tggatggcgg tgtcattgag gcggctcaag cgagcggagc
    12301 gactttctgg gacatcgtgg gtgtttacct atcagaaggt cttccagatt tgatccgtgt
    12361 gacgactgtg accttgattt cccttgttgg ggaaacagct atggccggtg cggttggagc
    12421 tggtggtatc ggtaacgtag ccatcgctta tggatttaac cgctacaatc acgatgtgac
    12481 catcttggca accattatta tcattttgat tatctttgca atccaattct tgggagattt
    12541 cttgactaag aaattgagtc ataaataaaa agagccgcgt ggctcttttt aactgatcag
    12601 attttctgtg caaatttttt actcaaggct tgtccaatca aggcacccac tagggctccg
    12661 atgacaatac ttgcgataaa tagaaggaca gttccagggt ttggagcgac catgatacgg
    12721 tcgatatatt cttgggattt tcctcttgcc agaagagtag ccatataggc tttgggcgca
    12781 atccacataa gcaagattgg tcctgttgta ctaaaggcga aaataatgaa agaaaggaag
    12841 ttctttgttt tgtccttgta ttttcctaaa tgagctactt catctgctag gaggccacag
    12901 ataattccag gaaggaagga accagcaccg tgtttagttc ccaagaaaaa gagggcaatg
    12961 acaaggccga tagtggtaat ggctccaaag cgcggaactt ttgcgactag gatcatatag
    13021 acgctaccgc cgacaagggc agtaaaggca ggcgcataaa acatgtttcc agtttggtca
    13081 aagagattgc ccaaaaggac accaatcccc atgcagagga agtaaagaac tgcaaaaagc
    13141 agtgtagtta agatagattt cttcatgaat tgtctcctga taattttttc acaattctca
    13201 ttgtaccacg gtttggtggg attgtaaatg gatactagaa gtttttgaaa acgcttgaaa
    13261 tatgatataa tggtttcata gttattttta ggggaatatc atgggtagat ttttagactt
    13321 tgtctttaat cgtttctttt tagggatgat tgcgacagcc ttcttttggc tattaacttt
    13381 agcaggaggg attatccttg gtctagcgcc ggctagtgcc accttgatga gcttatatgc
    13441 agaacatggt tatagctttc gggaatacag tttgaaggag gcttggtctc tttacaagca
    13501 aaattttgtc tcaagcaacc tgattttcta tagcttttta ggtgtgggtc tagttttgac
    13561 ctatggtttg tatctcttgg tgcaattgcc tcatcagacc attgttcatt tgattgcgac
    13621 ccttttgaat gtcctagtag ttgccctgat ctttttggct tatacagtat ctttaaaatt
    13681 acaagtttat tttgccttgt cctatcgaaa tagtctcaaa ttatccttga ttggcatctt
    13741 tatgagtcta gcagctgtgg ccaagattct ccttgggact gtgctacttg tagcaattgg
    13801 ttattatatg cctgccctgc tattttttgt aggaattggg atgtggcatt tctttatcag
    13861 tgatatgttg gaacctgtct atgaaatcat ccatgaaaaa ttggcgacaa aatagaatga
    13921 agcagttttg gctacatacg cttctaagaa cctatagttc agtgatgatc attatcattg
    13981 cgagttttgc aatcttactc tcttacgctg actgggattc acgtgaaaag gaagcccaga
    14041 gagtagccca gcgtgtaact gctagaacag tgagtgaaat tgaatattac catagagagt
    14101 caacccagat agctcaggct ttagttgaaa accaagctcg tattgaggga atctataaat
    14161 actttagtct tagcatgcca gactattttt actggcaatt agagcggaaa gcttcgcctt
    14221 atatatcagt ctctctgtat gaaaatgttg atgacctcta tgttcgaaat gattttgtaa
    14281 ctggagtggc cattgctttt caagattaca aggaagtcta tgtttctact aaagacaaac
    14341 gtagtggaga aaaaatcagg gctgaggatt tcaaaccagc aggaaatagt tttgccattc
    14401 cggtgtcaga tccagtgtca gatcaagatt taggagtgat ttacatctcc ttggatcctg
    14461 ctgttttata ccatgccatt gataatacta gaggtcatac tccgatggca gtaacagtga
    14521 cctcaccttt tgatacggag atttttcata ttggtgagac agttgataag gagagtgaaa
    14581 attggctagt tggcttaact tctcatggat atcaggttca ggtggcagtt cctaaaaact
    14641 ttgttttaca aggaacagtg actagctctg ctttgattgt gggtttgagc cttctcttta
    14701 ttgtcattct ttatctgact ttgaggcaga cttttgctaa ttaccaaaag caggtagtgg
    14761 atttagtaga atccattcaa gtcattgctc aaggcgaaga ggggcgtcgg attgacattt
    14821 ccgagaaaga tcaggaatta ctcctaatcg cggagacgac caatgatatg ttggatcgat
    14881 tggaaaagaa tatccatgat atttaccagt tagagcttag tcaaaaagat gccaatatgc
    14941 gagccttgca ggcgcaaatc aatcctcatt ttatgtataa tacgctggag ttcttgcgca
    15001 tgtatgcagt tatgcagagt caagatgagt tggcagatat catttatgaa ttcagtagtc
    15061 tcttgcgtaa caatatttcc gacgaaagag agaccctcct caaacaggaa ttagaatttt
    15121 gccgtaaata cagctatctc tgcatggttc gctatcccaa gtccattgcc tatggtttca
    15181 agatagatcc agagttagag aatatgaaga ttcccaagtt taccttgcaa ccgctggtag
    15241 aaaactattt cgcgcatggt gttgaccaca ggcggacaga taatgtgatt agcatcaagg
    15301 ctcttaaaca ggatggtttt gtggaaattt tggtggtcga taatggtaga ggaatgtcgg
    15361 ctgaaaagtt ggcaaatatc cgagaaaaat taagtcagag atattttgaa caccaagcca
    15421 gctacagtga tcaaaggcag tctatcggga ttgtcaatgt acacgagcgt tttgtgctct
    15481 attttggaga ccgctatgcc attactatag agtctgcaga gcaagccggt gttcagtatc
    15541 gtattacaat tcaagatgag tagaaaggga gaaaatgtat aaagtattat tagtagatga
    15601 tgagtacatg gtgacagaag gtctgaagcg tttgattccc tttgataagt gggatatgga
    15661 ggttgtcgca acagccagtc atgccgatga agctctagaa tatgttcagg aaaatcctgt
    15721 cgatgtcatc atttccgatg tcaatatgcc agacaaaaca gggcttgata tgattcggga
    15781 gatgaaagag atcttaccag atgctgccta tatcctgctc tcaggttatc aggagtttga
    15841 ttatgtaaaa agagcaatga accttagtgt ggtggactat ttggtcaagc ctgttgataa
    15901 ggtagagctg ggaaatctgc tggagaagat tgcaggtcag ctcggcgaga gagggaagaa
    15961 aagtcagact cttagtcaag aattagacga ggctggattt gttagttatt taggggataa
    16021 ggagaattgg tggataggtc tatccaagga aaaacaaggt tccttcacca ttccctacta
    16081 tgtcttgggt caagactggc agattttcat ttctggccaa cccttagatg gcttagtcgt
    16141 tactcccttt gaagctccct atcaagaaca ctttgaacgc tggaagctga atgctgagaa
    16201 aaccctcttt tacggttctg taaatctgca gcagtctgag agtctctttg cctattacga
    16261 accgatttat agggttatca ttcagggaaa tctcaatcaa atcgtagaag agttaaatct
    16321 cttggagaag gtagttcttg aaaatacgcc gcgtgttccg attactaaac agctttttat
    16381 tcagtttgtc atggatgttt tccatttatt tgaacatctc aaagctgatg acctgacaga
    16441 catcgttaaa accattcatg ctattcaatc cttcgatgaa ttggttcctt atatcaagga
    16501 aactctgacc agctttttcg gtcaataccg tatgaatgaa aatgtggtca gtgtgctgga
    16561 agtcattggt cgtgattacc aaaaagagct ttccctcaag gatatcagta aggctctctt
    16621 tatcaatcct gtctatctag ggcagttgat taagcgtgaa accgattcga cttttgcaga
    16681 gttactaaac aaacaacgta ttaaggctgc ccagcagctc ttgctttcaa ctagtgacag
    16741 catcgaagat atttgttatg ctgttggtta cagtaacctt ggatatttct ataaagtttt
    16801 ccgaaaattg tgcggaaaat cgccaaaagc ctaccgaaaa caggtagaaa ctatactata
    16861 agatttgtat tcctttacaa aatgtgctat aatattatca ggaggttcta tcatgaaaaa
    16921 gaaaccaatt tatctatggg tcttgctaat cttgtctgcc cttatttcag ttccgtctct
    16981 gtttggaatt gtgagtccct tgcctagtaa agaagccctt cgtgctgctc agaaacaagt
    17041 tgcaggggtc aatgctcagc aattagaaga ccagcttaat tatacctata gagtagcaga
    17101 agcatctcat tctattttta atgttgcttt gattgtgcta tctactattt tagtggtcgt
    17161 agcgattgtc ttccttgttc gtaaaaattt gcaatatgca aactatactt acgttggcta
    17221 tgttttgtta gctattattg gttcgattta tggctatgtt ggtttacaag atgctgtgca
    17281 gttggttcaa gatgagagca tgcgtttgac agtgagtatt ggttcaaaag ctgttagcat
    17341 tttctatatc gtcatcaatg ttctcttcct agcccttgtc ttctataaga tgtggcgaca
    17401 acagaaagcc ttggcagaag aagaggaaac agaagagctt gcctaagtat tgacaaaaaa
    17461 gaactatcaa gatacaatct tggtagttgt tttttgatta tagataaaat catggaggta
    17521 catatgaaga caatttcttt agtttatatt agtttgagtg gcaacactga aagttttgtg
    17581 acgcgcttga aagactatct cttgtcccag tacaaaggga ttgaggttca aaagattcat
    17641 atcaaggatt tggtcaagga aggcaaaaat ttctacgaaa tggaccatcc ctatgttgct
    17701 tttttgccga cctatctcga aggtgggaat ggcgtggata acggagatgt tgagattttg
    17761 acgacaccgg tgggagattt tattgcctat ggtaacaatg ctagtaagtg ttttggtgtg
    17821 gttgggtcag gaaatcgtaa ctttaataac caatactgcc taacagccaa gcaatacagt
    17881 caacgctttg gctttcctgt attggctgac tttgaaatgc gaggcatgct ggaagatatc
    17941 aaacatgtcg cagctattat cgcagatttg tatgagttgg aaaaggagaa ttaatactca
    18001 atgaaaatca aagagcaaac taggaagcta gtcgcaggtt gctcaaagca cagctttgag
    18061 gttgcagata gagctgacgt ggtttgaaga gattctcgaa tagtataaag ttcttataag
    18121 aggtggttga agttgttcaa ctgttttttg agtataaaca gtctttaaga acgtaaaaaa
    18181 gcataagttc aggtcttcaa aaccttgttc ttatgctttt tatcatagaa atatttgctg
    18241 aattttctct tgaaatgaaa ccttatcttc atctcgcgct tgtcccttac cctgcttttc
    18301 cgattgcgag tgcgtagata aagaagatgg cgaagccaaa gaggaaaatc aatcccgcaa
    18361 tggcaaggtg tttgagccaa gaaggaagat ttttgttttc acgtgttacc aaggcgtaat
    18421 tcaaaagagc aaagaaaggt gttgtcagga aagagccaat catggcaaag cggagcatgg
    18481 ttgaaacctg accagcgaag aacttgataa tgatgatacc gatgatagca gtgatggtca
    18541 tccagatgtt caaagattta cgattatcct ctttttgact gattagcagt cggagagatt
    18601 cctgattaac gcgagaatag ccatcgataa cagttataac tgttccaaag atacagagga
    18661 aggcaataaa ggtaatcaag taacgggacc attcgccaag aacagaggca tacatgccca
    18721 cgaattgaga gatgtatttg gctgaagcag cttcaaccgc ctgccctgta ggatactgaa
    18781 tcagtgctcc cagtgccaca aagaagacgg ctaggatagc tgttccaata taaccagtgt
    18841 taaagtcaaa cagagcgtct tctgtgttaa agttgacggt ctttctcttt tcagctgacc
    18901 aaagtgaatt gatggctgaa atttcaatag gagccggcat ccatcctagg agggagacga
    18961 tgaagggcag agctgccatt tgccaaggtg tcttctcgac aaaatcagaa ctgtattctg
    19021 gatgcttgac cgccgcaatg ataactgcaa gaacagtcgc aatggttaag gcagacataa
    19081 tccatttgac catgccgtct aaaagtttgt agcctccaaa gagtagcata gcccaaatga
    19141 ttgcaacgag aatgagggac cactgagtaa tgctaagtcc aatcattggg aaggcactgg
    19201 cgatgatagc tgagcacaga atggcaacac cagccgtgtt gaccatagcc gaaaagacat
    19261 tgaggataaa gaaaatccag agatagagtt ttcctttttc ggcataacct tcaaccaaag
    19321 tctttccagt atcagctgtg tattcagcac caaaacggaa aaatggatat ttaaagacat
    19381 tggctaagat gaccaagaga agtagagacc aaccgtaaga accgccagct tgagttgagg
    19441 atacaatgtg ggaacctcca acagcggcag ttgccattag gattccaggt cccattgctt
    19501 ttagcttgct tgcccaggtt gattgattta aggaaatagc ttgcgacatg ataaatactc
    19561 ctttttgaat tttcagaata atctgtatat gtaatctata ttctacaaaa aattttggaa
    19621 aaatgcaaga gtattttgaa aaaagataga aaatttacaa agaaaatctg aaataactgt
    19681 tatgatatag aggattgaaa ctagaatagt acacctctgc ttctaaaaca ttgttagaaa
    19741 tcgatttgac tgtcctgatc gatttatcct gttcttattt catttcacta tagtaaggtg
    19801 cagcaggata aagaaaaacc gagaagtttc tttctcggat ttgcttatta tgaggttcct
    19861 attttctatg ctccaagagt tgattgatgt gatctacttt tttagcctct cttttataga
    19921 gaatagccca gatgatgaga tagacaatcg caaactcgat aatgagctgg aggtagaaaa
    19981 tccagtggaa agggaaccaa ccagcaagag ttgctagtgg gacaaagcca gccagcataa
    20041 ggaagaaatg agtcagagtg gcacgaagca tgctccagtc acggctaaat aagcggttgc
    20101 caaagttgaa gagcataccg atggttgccc agataagtgt gcagtagagc aagaccaggg
    20161 caccgtgaac ctgatgctga tccatcactt ggccgatgag agagtaggga tttagtggtg
    20221 cgtaggtatt tggtgcataa atgagtgaaa agaggataga gaggatgagg ccgataagaa
    20281 caccggtagc tgcatcgtga aatacttgtt ttttcatagt tctaatttct ccttgatggt
    20341 ttttagataa cggcgtgaag agtaggtgaa gctttcgttt ttcaagaaaa tttctaccag
    20401 accgtttggc gtgagcttga ggtgagagat ggaatcgata ttgatgattt ctgattggga
    20461 aatttggata aaattggttg gcaagagttt aagaacctga tagagtcgca aatcaatgct
    20521 gtaggtctga ctcgcggttt ctgctagaac cttccgattc tcgatataga agcgctgaat
    20581 cttgccaatc tcaactagat agacctgatc atcgattttt cctttgattt tttctctttg
    20641 gtccagattt tctgcgaact cgatgacttt ctggactttt tcggtttctt gaggtgcttg
    20701 gacaatcagc ttttcctcct cgtaagtctc actaatctgt agttctactt tcatagtttt
    20761 ctctcctttt cagttataca aggttgtgat cacttcctgt atatccttat taaacactat
    20821 tttatagccc atggcaagga accttgtcta tgtggaggga ttgggctcct atgtggtgga
    20881 gcttttctgt tctttctgaa atatggtata atagcactaa tcaatttcta ggaaaataga
    20941 tacggaaagg ggctgaaaga actaggggaa cagttggaat tagaaagtga taggtatgaa
    21001 aagtggcgtt gaagctgaat aagtttataa agcgtttgaa tgaagaaatg gaaagtaaat
    21061 aagttgacga tgaattacaa aatagatttt atctacaatt tgtatctttc aaatcattga
    21121 tttgaatttt agatttaatc atgttacaat taaaactgaa atcaaataga agaggaaaat
    21181 gcaaacgtgg gcacactatt agcaacaaga ttaaaaaata gacggaaaga attaaaaatg
    21241 tctcagcgag aactagctga aggtatctgt aaacaggggc aaatcagtcg attagagagc
    21301 ggagagttta cccctggagc ggatttcctg aatgcccttg ctaagaagtt aaaagtcagt
    21361 atggattatt tttttgatga gcaggttgta gagaaagttg aggagttatc agaatttaag
    21421 aaattagcac agacatttat tacaaatcgc aattatgagt ctttgaaata tatatatgaa
    21481 ttggagaatg taaaagctca ccgcctatct ttagcagata aaatctacat ggaatggata
    21541 aaatctctga tagattttta tttttacgga cagaaagaag atgcgattgt acgattagag
    21601 ggggtattat cacagttaag tgtatctgat ttgaactatc tccaagtttc aaacacccta
    21661 ttcaattttt attatgatat tggagattta ggtcgtttca ataaaattcg tgaaaaacta
    21721 gagtatcaag taaatcacct caatttgagt acaatcgaag agttagaact atctattaag
    21781 tttaactaca acgtttgtcg ttatctatgg ttacagaaaa atattgaaga agctattact
    21841 aaaattacag ctactataaa acaatgtaag gcttacagaa cgaattatct tttggctgat
    21901 ttgtacttat tgatgggaaa tgtaagtgaa aatttttctt ctaaaagttc ggtgaaagaa
    21961 tattttgaga cggcatattt tctatacaaa cttgaggaga acatgtcaat gactctgaaa
    22021 gttgagcatt acattgcaga tataacagaa taatgaatac ggtgttcaag tgagcatcgt
    22081 ttttcaaacc tagttcagat acaaaaaagt atcaaacaaa aaaaaataaa aaaacattat
    22141 aaaaacaatt gacaagctaa ttttgaagtg ataaaataaa tgcaagaaaa caaaaggaga
    22201 ggtatatgag aagtttgttt aagaaaatag ttgctgtatt agttattggc ttaattctgt
    22261 taggaattgc gagaacacct caagttcata agatggctag agggattgat cctggtcctg
    22321 cgaattttat ttagaaatca atttctacta attgagtact aattgagtat taatgggtaa
    22381 aaagattgta tggataagaa aaatttactt gtattggtta ctggttcggt aggtgccagt
    22441 aatgtagata catacttata ttatataaaa aaattctata atgttaaagt gatactttct
    22501 gaaaattcta aaaaatttat aagtaaggaa ttaattagtt atttttgtga taaagtttat
    22561 gatgaaatat ttgttgaaga ggtagttccg cacgtttttc tgccatatga atctgactta
    22621 cttcttattt taccagctac ggcaaatgtg attggcaaaa ttgctaatgg tattgctgat
    22681 gatttagtta cagcaactgt tttaaacttt aataaaaaaa taattttttg tcccaatatg
    22741 aactctacta tgtgggacaa tcacatagtt caaagaaatg tatcaattct aaaggagttg
    22801 ggacatatat ttttatttga gtctaaaaaa acatatgagg taggattgcg taaagcaata
    22861 gattcaacat gttcaatgtt acaaccacag tcgttagtaa aagaacttat caaattagaa
    22921 aatattgtcc ttgaagaggg acattaaaaa ctactgagaa tattaaggag gggaaaaaat
    22981 ggaaaattca tcaatcgatg tagatatgct gttggaagaa ttgacacaag aagcaatggt
    23041 cgttgttgct gttgataagg actgttaatt taaacttatg gcaatatatg aaaggttact
    23101 ggatgtttta aattatgcag gcagtagcct tttattatat acaaatggat aaagtaagga
    23161 taatacaatg attaataaaa aaatacaaca agttgttttg gaatcattac agaatttttt
    23221 gaatgggaac ttcatttcgc cttgtgtagt ctatgatttt ggcttgctgg aaactgtact
    23281 tgatgaattt aaaaatcaaa ttcctgtaac attcaattac caactttttt atgccgttaa
    23341 agcaaattca aatgagaaga tacttgaatt cttagtagat aaaattgatg gagttgatgt
    23401 ggcgtcatta tctgaattag atgtggctaa aaaatttttc ccaccaactc aaatttctgt
    23461 taatggtccc gcattttctt atgaaacttt atataatctg attaaaaaac aatataaagt
    23521 tgatattaac tttttggaac atcttcaaca attttcccca aaagaatctg ttggaataag
    23581 agtaacggag ccagatgaac ttaataatcg tatgagtcga tttggaataa atatttgcag
    23641 tgataattgg actagtaatt tacaaaatcc tttaattaca cgactgcatt ttcattttgg
    23701 agaaaaagat gataaattta ttgttaagtt agataaaata ttatttaagt tacaagaaat
    23761 taataaactt agagaggtta gagaaataaa tcttggaggc ggttttatga aattatttat
    23821 ggaaaatcgt ttgaaagaat tttttctatc acttatggaa atctataaaa agtacgatat
    23881 tgatagtact gtgactacaa taatagaacc aggtagtgca attacttcat tttctgccta
    23941 tatgattact agcccagtta atgttagtga ggtgaatgag cagcaggtta tcacgttaga
    24001 cacatcaata tacaccaata cattatggtt tgttccgcat attattacaa cgttaaattc
    24061 aagtagtaaa gagcgttata gtactattct ctatggtaat acctgttatg aacatgacaa
    24121 gtataaaatg aaagtttcgc ttccaaggtt aactcaaaat agcagtatag tgttttttcc
    24181 tgtaggagct tatataaaaa gcaatcattc aaatttacat cgtaatgatt ttatgcggga
    24241 ggtatatttg tggacaaaaa acttgacata ttagataaag ttaaggaata tttaggaaat
    24301 aaaactactc aaattctgga taatcaatat aaagaatttt tgaaacttaa tgatataagg
    24361 cgagcgtttg gtatttcaga aaaagtatta aacaattctt ttaattttac gagtaaagaa
    24421 tttaatgatt taattaataa cgaaaattat ttattcgaat atgcatgtag aattagagag
    24481 gaatggagaa aaaaatgctt taatcattct tatcgttttc tatgctcacc tataattaca
    24541 gatgattttc ttaacacgaa gacattgaga agtagccaaa ttgaatataa atatgagcga
    24601 tatttatcga aaagttcgat aggcgataga gcggttgatg gctttgtttc cttcaatact
    24661 ttaacagcta atggtatgtc tgctattaaa ctatgtcttg agatattaaa ctctattttc
    24721 ttcaagaaga agattgattt attatattca accggatatt atgaaacaag atttttatta
    24781 aataatcttg ctaaatcagg tattagttgc tatgaggtaa gtaattgtga attggataaa
    24841 gataaatttt ataatgtatt catgatggaa cccaatcgag ccgatttaac attacaaaaa
    24901 actgatttca agatagtaga atatt
//
LOCUS       DAVLHM010000030        24517 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLHM010000030 DAVLHM010000000
VERSION     DAVLHM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.030"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(299..517)
                     /locus_tag="VXE45_001393"
     CDS             complement(299..517)
                     /locus_tag="VXE45_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789414.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(763..1041)
                     /locus_tag="VXE45_001394"
     CDS             complement(763..1041)
                     /locus_tag="VXE45_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789415.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1255..2886)
                     /gene="rlmD"
                     /locus_tag="VXE45_001395"
     CDS             complement(1255..2886)
                     /gene="rlmD"
                     /locus_tag="VXE45_001395"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0789416.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKIFMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2960..3934)
                     /locus_tag="VXE45_001396"
     CDS             complement(2960..3934)
                     /locus_tag="VXE45_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0789417.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4008..4622)
                     /gene="pmp23"
                     /locus_tag="VXE45_001397"
     CDS             complement(4008..4622)
                     /gene="pmp23"
                     /locus_tag="VXE45_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0789418.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4622..5596)
                     /locus_tag="VXE45_001398"
     CDS             complement(4622..5596)
                     /locus_tag="VXE45_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0789419.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5604..6860)
                     /locus_tag="VXE45_001399"
     CDS             complement(5604..6860)
                     /locus_tag="VXE45_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0789420.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6922..7353)
                     /locus_tag="VXE45_001400"
     CDS             complement(6922..7353)
                     /locus_tag="VXE45_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789421.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7355..7957)
                     /locus_tag="VXE45_001401"
     CDS             complement(7355..7957)
                     /locus_tag="VXE45_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0789422.1"
                     /translation="MIDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7941..8780)
                     /gene="prmC"
                     /locus_tag="VXE45_001402"
     CDS             complement(7941..8780)
                     /gene="prmC"
                     /locus_tag="VXE45_001402"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0789423.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     RQD"
     gene            complement(8780..9859)
                     /gene="prfA"
                     /locus_tag="VXE45_001403"
     CDS             complement(8780..9859)
                     /gene="prfA"
                     /locus_tag="VXE45_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0789424.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLKELNK"
     gene            complement(9869..10348)
                     /locus_tag="VXE45_001404"
     CDS             complement(9869..10348)
                     /locus_tag="VXE45_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789425.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFCFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10338..10937)
                     /locus_tag="VXE45_001405"
     CDS             complement(10338..10937)
                     /locus_tag="VXE45_001405"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0789426.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPIMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            11061..11243
                     /locus_tag="VXE45_001406"
     CDS             11061..11243
                     /locus_tag="VXE45_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0789427.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11380..12753
                     /gene="mnmE"
                     /locus_tag="VXE45_001407"
     CDS             11380..12753
                     /gene="mnmE"
                     /locus_tag="VXE45_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0789428.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12800..13735)
                     /gene="dapA"
                     /locus_tag="VXE45_001408"
     CDS             complement(12800..13735)
                     /gene="dapA"
                     /locus_tag="VXE45_001408"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0789429.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13791..14867)
                     /locus_tag="VXE45_001409"
     CDS             complement(13791..14867)
                     /locus_tag="VXE45_001409"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0789430.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15209..15281)
                     /locus_tag="VXE45_001410"
     tRNA            complement(15209..15281)
                     /locus_tag="VXE45_001410"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15246..15248),aa:Thr,seq:ggt)
     gene            complement(15381..15890)
                     /locus_tag="VXE45_001411"
     CDS             complement(15381..15890)
                     /locus_tag="VXE45_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0789431.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIQKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15888..15984)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            16013..16444
                     /locus_tag="VXE45_001412"
     CDS             16013..16444
                     /locus_tag="VXE45_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0789432.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16526..16903
                     /gene="mscL"
                     /locus_tag="VXE45_001413"
     CDS             16526..16903
                     /gene="mscL"
                     /locus_tag="VXE45_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0789433.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16945..18039)
                     /gene="hemH"
                     /locus_tag="VXE45_001414"
     CDS             complement(16945..18039)
                     /gene="hemH"
                     /locus_tag="VXE45_001414"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0789434.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(18117..18992)
                     /gene="srtG2"
                     /locus_tag="VXE45_001415"
     CDS             complement(18117..18992)
                     /gene="srtG2"
                     /locus_tag="VXE45_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
                     /protein_id="HEV0789435.1"
                     /translation="MTVQKRARFKNVFLVFFCVFVALFSWQRVVEASDYDHYNPIEKD
                     ASSTGFETLQHLNKDVCGWISLDGTKVDYPLLQSQDNVKYLDRNAFGDYTIMGSIFLD
                     YRFNPNFTDFNTIIYGHSMASGAMFGEIKKFADKEFFDQHRYGSIYYNGRERGLEIFG
                     ILEVDAYDTEIYRTLSSKDEEHQAYYQYLLSKAKYKRDVSLTSTDKIVLLSTCFLNIT
                     NGRHILLAKITDAPVKVAQDESGEAVGTRYFDHGIPSHWIYILAFLLLIIVLLLLVLI
                     ILIIRRDKKTKEQKK"
     gene            complement(19070..20068)
                     /gene="srtG1"
                     /locus_tag="VXE45_001416"
     CDS             complement(19070..20068)
                     /gene="srtG1"
                     /locus_tag="VXE45_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HEV0789436.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(20086..21282)
                     /gene="pitB"
                     /locus_tag="VXE45_001417"
     CDS             complement(20086..21282)
                     /gene="pitB"
                     /locus_tag="VXE45_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HEV0789437.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(21327..21878)
                     /gene="sipA"
                     /locus_tag="VXE45_001418"
     CDS             complement(21327..21878)
                     /gene="sipA"
                     /locus_tag="VXE45_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HEV0789438.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21878..23638)
                     /locus_tag="VXE45_001419"
     CDS             complement(21878..23638)
                     /locus_tag="VXE45_001419"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789439.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYIGSNDSI
                     TSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQL
                     LPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYVL
                     KFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDYS
                     EKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTSP
                     VQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLTV
                     KKILEGEQSPNKSFTINVTLSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYLP
                     RDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVIKKVTGAFANLL
                     QSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLNA
                     RYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVVL
                     PLGGIFFIILLGHLVVNRRK"
     gene            complement(23960..24463)
                     /locus_tag="VXE45_001420"
     CDS             complement(23960..24463)
                     /locus_tag="VXE45_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HEV0789440.1"
                     /translation="MNVQYDFKKIQYFTSILVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
BASE COUNT         7047 a         5117 c         4527 g         7826 t
ORIGIN      
        1 aaaaaggatc tagtttttat ttttagttaa attatgtcta tatttttcat taactcatca
       61 ataaaaattt gtttgctaat atctctttct tctgattttg tttcaaggat tattgctaca
      121 tcattcatat ttttaggtaa ataccaacca tctggcttat ctgaatatcc cttgaagcct
      181 aattgattaa aagtagttat ttgaccagta ccttgattga tgttttcttc aacttcatta
      241 aagcctatac ttctcttgca taatccctaa cttgatcttc tgtccttaaa gtcattttct
      301 attcctcgtc actaaaatta tcttcaaaac taataatatc attaggagtg caagataaag
      361 ccttacatat tctttctaaa ttcttaaatg taattggttt atcctttccc atttgtgcca
      421 taacatttgt tgtaagtcct gccatagcta ttacatctgt tttctttagt cctttttttg
      481 ctaactgtat ccataatggt ttatagttaa gtgccataat atccctcttt ttttcttcat
      541 tagatttatt taattatagc ataaatattg atttcattca atcttacatt gatttagtga
      601 tttgttttag agaatttgtt gtgttattcc gtccttattt tgccataaat tgttttaagt
      661 gggacctctt atccttacca tttttacctc ctaattttga gtataaaaaa gacgatagag
      721 tttttaattt ctatcgtctg agatttacat attaaatttt catcacaaaa taagactctt
      781 taaagaatct ttaaattcat tggtatgctg cttacaatat ccattattaa aatggatatt
      841 gtaagcagca taccaactat ttattttttg agttttaaac tttggtagaa gtcttgaact
      901 ccttatattt acataactat ttgcctctat aactgttatg acacgaaacc aacaagcaag
      961 ttcaagcacc tccatatctt tattcaaatg aggactaaga tattcacaaa ctttatcata
     1021 aacctcttta tcttttttca taaaaggggc atacaactta gcaaatttat cctaaaattt
     1081 tttgttgcct ttatcaatca tttcaacgct cctttaaata taaaaatgat cctatcaatc
     1141 tttatattga gcctattttc taattgatac cttgcaagaa aggaataata gctgttccta
     1201 taccaagtag gaatgtaata aatgcagaaa gtcatatact gtcattcttt tctattaaat
     1261 cattttgaag tgtctcaaag catccatgat ggcttcttct ttttcaggtg tacactgtgg
     1321 aataatttgt ttatcctttt tagacttgtt gtaatgttct cgtaattcta ttccacattt
     1381 cttttttatc tgtgcaatat ataatgtcga aacttttaat tcaaatttat tccaaacata
     1441 ttctttgatt tgagcatatg ttgctttgct ctccgcactt gtcaaatcca tctcatccag
     1501 ctcaatttca acacttatgt gcttatcgac atcaagtttg gacaaaagtg ctaccgtctc
     1561 gacgtgatgc gtttgaggaa atagatccac cggctggact ttcttcaatt catatcccaa
     1621 ttcttggtag agtttgatat cacgcgccat ggttgcgaca ttgcaggaga tataggcgat
     1681 gcgatcggct cctgtttggg cgcttgcttt gataaagctt tctgtcaagc ccttgcgtgg
     1741 aggatcaacc aagataacgg ttggttgaat cccatcttta agccaattct tcatagcatt
     1801 ttcagctgtg tcacagacat agtgggcgtt tgaaatattg ttcagctgag catttttttt
     1861 actattctca accgcttctg gaatcagttc aacaccgtag acttctttga catgcttggc
     1921 gactgataaa ccaatggttc caataccaga ataagcatca ataaccacgt catctttttt
     1981 taactctgca aagtcaatgg ctgtttgata gagtttctcc gccatttcag tattgacttg
     2041 gtaaaaggct gggccagcga tttggaagtc atttcccaac atctggtccg taatatagtc
     2101 ttgaccataa agagtgcgcc actccttacc aaaaatcgca ttggtattct ggtcgttgat
     2161 attttgcatg acagacacaa tctctgggaa ctgcttgata acttgttcaa tcaattggtc
     2221 aacacgaaaa acttttggac gagttgtcac caaaacgacc atgatttgtc ctgaatagtg
     2281 accacgacgc accacaagat tccgaatcaa tccagactgt tccttttcgt cataaggttt
     2341 taaatcaaaa cgacggagca ggtctcgaag agctactacg acttggtcaa tgacaggatc
     2401 ctggataaag aaatcttcaa ggggcatgag gttatgcgaa ttcttacgga aaaatcctgt
     2461 ttccaagaca ccattcactc gacgaacggg cacctgcgcc ttattgcgat acttgactgg
     2521 atgttccata ccaagcgttt cagcaacttc tacatctgca attccagcaa tcttgtagag
     2581 actgtccttg acttgcttgg ttttaaactt gagctgttct ggataagaaa ggtgtcctaa
     2641 atccgcgatt cctgaacgca ggtaagccaa atctagatct tgattacggt gtggtgactg
     2701 gacaaggtat ttttcaactt ttccaaagcc aatcttttta ttgaccttga ggacacgcat
     2761 gaaaattttt tcactcggta aagcattctc tacaaaaaag accaaaccat ctaccttggc
     2821 aactcctgcc ccttcatggg tcaaatcaac aatttcaact tctacaatat catttttctt
     2881 taacattctt ttctctttct attggccgac aaaaaagacg gcaacgttac ggttaccatc
     2941 cattatacca tgaaatttct taagaaccaa aactcttgaa gaagttgaca agggcttgcc
     3001 agagggagct taagaagtta ccaccgtcct ctagcgcctt atccgcatca aagttaaggt
     3061 tgatattttt aaaactgtcg ccagcttgtg atacgatgct ttgtttaagg tcatttaggg
     3121 ttttagtgaa atctgcattg ctgaggatat cactctttga gagattcaag gcaaaattga
     3181 tgatgatatt gatctggttt cctgttatga cctgatcaag tttgtaattt tttaaggtat
     3241 cttcaacaat cttgcggata tcttcttctg tcagatttcc cttgctttct ttagctttgg
     3301 cgagtcctga cttgatatca gctagggcaa cgtttaattt attagcatca tagcctgatt
     3361 tgtccttgtt ttcagcattg atatctgaca aagcctttag ctcttcttga gccaaatctt
     3421 tattggcttg cggcaccttg gctccattag cttctagcga atagtagatc ccagccaaag
     3481 cactctcacc tgtaactgga atgggtgctg ctacagtgat tttggcgtgt tccacaccca
     3541 aagttacggc tgcatttcgg tacatatcct gagttacctt agtgatgttt tcaggtgttt
     3601 caatcttgac ctcaagtggc gatttgtcac ctagcttttg aatcttggct gatgaataca
     3661 actgtaagct agagtcattg gccacattca tgattttaga ataaacatca ggtgtcatgg
     3721 tcttgagttc tttggtatct gttgaggcat tgtagcccag ttttttaaga gtttgatttt
     3781 tttggtcttc agatagggaa gaacctagga catattcagg ttggacatag gtttcatcga
     3841 taactttttg aacatctgtt gctgcatgga cgctattcat agctgttact gcccacaaga
     3901 tcgcagcgct agtcagaaag agtttctttc tcatagggaa tttcctcctt tacttcttta
     3961 gagtaatata tctatcttaa agaaaactta taacaaaaac acctggtcta gccagatgtt
     4021 gaaaagagag tgaaacattt gatgatgtaa aggttaagtc gtacctgtct agaataataa
     4081 tagtttcctc catttacata gagttcagca ccgtgaaaaa tggaaatggg gtgaatataa
     4141 ctataagtct ttccagtcgt attaccaagc aagggggcaa cagtctcacg agagtactgt
     4201 ttggctagag ccaaggtatt ttccttgcca ttttgggcga taaaatcgat ataggcaggt
     4261 ccaaaattat aggcttgaac agctgtccag atatctacac ccttcttctg cgccagatag
     4321 agattgcctg tcagagtttg aatgccttgc cgaatgctag aggcattatc attgatggtg
     4381 ttggtggaac cacttgcaga ctcactagac tgcataacat cgccttcttt tccttttgtt
     4441 tcagtataaa tcatagcaag cacaagctct tcgtttgctg gggtgtcttt ttcactcaat
     4501 atttctcgca ccatgggttg ataggtcatg acttgtttga catcttgatg aacgcggtaa
     4561 gctttatagc cagcaaaaag gaagactgct agtacaagca ctcttcgaat tcgtttaaac
     4621 attatttact ttggatatcc tcgatatttt tgattaagat agagtaggtt ccattttcgt
     4681 tttggataaa ctcaacagac tcggcgtctt gatagacgtt attgggaacg atgagctcaa
     4741 ttccatttga taaggagagt ttttggtttt caaatttctt taattggcga ctggcatcaa
     4801 tttcatcaaa ttgaacaggt tctggtacgg cttctttgac ttggtcaata aagctcaaac
     4861 gagccgtcag attgttgtca aaaaggtcat tagccaattt ctcaggtgac aattcattgc
     4921 tttcttctag gttgttgaaa atagctgatt tgaccttgga ttgaaattga aaatcatctg
     4981 tgttaaaaga ttcagcaatt ctctgggctg ttttttccag ttccttgata gattttttag
     5041 gagaaatctt aggagcgaca gcaagaagat tatctgaaaa atagttcaaa aaagtcccgt
     5101 tgtacttgat tcgtttttca atcaggtgat acttgcgact ctgaagattg accaccaagg
     5161 cctcgtcagc acccgttcca aatccaggca ggttattctg agtcagcttg attggattat
     5221 caacttctcc tccgaggtgg gtcaaggtct cccgcagggc aattcgcaag aaagcgaaat
     5281 gttctacacc ttctttagaa aattgaacaa aaatcaagtc attggtcttg agattttcag
     5341 aaatgctaaa ctcctctttc cagagattag ccagcgttac tgatgtctcc aacaaatcgt
     5401 ctgtaatatg attgaagaag ggattttctt cttcgaaaat cccagtcttg gcttcatctg
     5461 aatacacatg ttcaattttt ttacgtaggt attcttcgat ttttggagta atattgagaa
     5521 acttatctgc taagaacagc tcggtatcat ccggactgaa ctggtgaata atggctttct
     5581 taatataaat gtccataaaa gttttattcc tcgtataatg ggaaggcatc tgtcaattct
     5641 ttgactgcac ttctcacttc ttctaataca gcctcatttt ctgaattctt aagggtttta
     5701 atgatgagtt cagccacttt gcgactttct tcttcaccaa atccacgtgc agtaatggct
     5761 gctgctccga tacgaatccc acttgtcttg aatggtgaca agctttcgta agggattgag
     5821 tttttattta aggtaatatt gacttcatcc aacaagtttt gagcaacttt gccgttttct
     5881 acaactttag tcacatcaac aaggaagaga tggttttcag ttccacctga aataatacgg
     5941 aaatcagggt cttgcaagaa gacatctgcc atagccttgc tgttcttaat tacattggca
     6001 gcatattcct tgaaggctgg atccaaaact tctttgaagg aaactgcctt agccgccaca
     6061 acatgctcta aaggaccgcc ctgaatacct gggaaaatag ctgaattgat ttttttagca
     6121 agttcttcgt cattggtcaa aatcaaacca ccacgaggac cacgaagggt tttgtgggtc
     6181 gttgttgttg tgatatgagc gtatggaact gggcttggat gaaggccagc cgcaaccaaa
     6241 ccagcgatat gggccatgtc caccatgagc ttcgcaccga cagcatctgc gatttcacgg
     6301 aattttgaaa aatcgataat ttgagaatat gctgaagcac cagctacaat cagttttggt
     6361 tttacttctt gggcttgttt caagatagca tcaaagtcta agagttccgt ttcaggatca
     6421 acactataag aaacaaagtt gtaggtttga ccagagaagc taacaggagc cccatgagtc
     6481 aaatgaccac ctgatgccaa atccattccc ataaccgtat cacctggctc aatcaaggac
     6541 atgtaagccg cacagttagc ttggcttcct gaatgtggtt ggacattggc aaatttagca
     6601 ccgaaaattt cttttgcgcg ttcaatagca agagtctcta caacgtctac tacatcagtt
     6661 ccaccataat aacggcgtcc tgggtaaccc tcggcatatt tatttgtcaa gatagaccct
     6721 tgagctgcca taacagcctt ggaaactacg ttttccgaag caattaactc gatattattt
     6781 tgttggcgtt cttcttcttt ggcaatagca ttccagagat cagcatcata tgctttaaaa
     6841 tcatctttgt caaaaatcat aggtcttctc ctttattgtg tgactagtcc attagtttga
     6901 ttttacaata agaaaatcaa actaaaagat gcgaataaac cgtttctgca ttttatcaca
     6961 agtatagcca actttttcat aaaatgcatg agcacccaga cgatgattgg cagaatttaa
     7021 gcggataaac ccataaccac atcttttggc ttcttgttcc aacccttgta gtaaactttt
     7081 accgatacct tcaccttgcg cttgaggtga aactgctaaa gctaagatat taaatcctgc
     7141 tttggaatag agtgattcgt aaacttcagc gtggacatat ccaagtaaga catgattagc
     7201 tgcatcctca tagccaagta ggaaatgatg ggaatcctga gacagtctag ctagttggct
     7261 agccgtttcc tctagactaa aagtataacc caaagcctct tggttgatgt cacatatcgc
     7321 tttcacatct gtttcttgca aatctcttag catttcaagc ctcctcaaaa gaaatctctg
     7381 gcaaccgagc aagaatatct tctcgtttaa ttgcgccttg gcgtaagatt ttcaccttgt
     7441 ctccagacaa atccacaata gttgaatcct gtccagttag aaaagcatcg tcttccagac
     7501 ccagaacctc ttggtcaaaa tccttcagaa tttgttcaaa ggttacacca cttgcctgac
     7561 ctgagatatt ggcagacggc ccaatcaagg gacctgtctc tcgaattaaa tccagtgtga
     7621 tagggtgact gggcatccga aatccaatag ttgcaaggtc agaatttacc caatagggaa
     7681 ctcggtcatt ggcttcgaga ataatggtca agggacctgg caaaaaggtc tctacaagtt
     7741 tttgtagata agttggctga ttcttagaaa agtgcaagat atcctcgaaa gaggcgatat
     7801 tgagattgag tgccttatct ctaggacgac gtttgagttg gtaaacatgg tcaactgctt
     7861 tttcatctaa ggccttggca aaaagaccat aaacagtctc tgtaggtaga acgacagctc
     7921 caccattttc caactcttgt ctaatcctgt ctatcatcaa ccacgaccat cctattttga
     7981 ccaaattggt ccttgagtgt tcgaactctt ttttcaggaa gatgtttcct aaaaagttcg
     8041 ggaacacttt gaccttgctt gtatccaatt tcaaggtaaa tcttaccacc atctttgaga
     8101 tagtcttttg catcttccgc aattctacag taaatagcta ggccatcctc gtctgcaaag
     8161 agagctagat gaggctccga atgcaaaaca ttcaagccta cctctgactc atcttcacga
     8221 gagatatagg gtggattgga tacaattata tcatattttt cagaaatttc tgcaaaacaa
     8281 tcagattttt taaaaaatat attaagattt tgattgctag cattctctga tgcaagctct
     8341 aaggcctctt gagaaacatc tgctgctgtc actgaccaat ctggtctatt ttttgctaga
     8401 gcgagagcaa tagctccact acctgttcca atatccagaa ctgaaagatt cgtctcaaga
     8461 ttttcagtta gaataagctc cactaactcc tctgtttctg gacgaggaat caaaacccgt
     8521 tcatccacct ttaaatgcat tccataaaaa tctgcctgtc caatgatgta ctgagctggc
     8581 ttgtgagctg ctagttgctg gtaaatatct tctacaaatt gtttttcttc ctctgttgtc
     8641 acctcctgct ggagggcaaa aataaagtct gtaaaagata gatttttcag actacgatag
     8701 acaaaagaga ggctttccgc ttcctctcct tgtcttatca actcttcttc aaaatttgaa
     8761 aataattgag ctaatttcat tatttgttta attcttttag tttttgtgtt tggtcataaa
     8821 gcaccaaggc atccacaact tcgtccaatt taccagacaa aatcgtatct agtttttgga
     8881 gggtcaagcc gatacggtgg tctgtgacac ggttttgtgg gaagttataa gttcggatcc
     8941 gttctgaacg gtcaccagta ccgattgtcg acttacgctc agcgtcttgt tcatcctgag
     9001 caatctgagc aaagtggtca gcgacgcgtg cacggataat cttcatagcc ttctcgcggt
     9061 tcttctgctg ggtacgttct tcctgcatct caaccttgat attggttggc aagtgaacga
     9121 tacgaacggc agtcgcaacc ttattgacgt tctgtccacc agcaccagag gcgtgataga
     9181 tgtcgacacg aaggtctttt ggatcaatgt cgtattcaac ctcttcaact tctggcataa
     9241 caagaactgt cgctgtcgaa gtatgaacac ggccttggct ttctgtcaca ggaacacgtt
     9301 gcacacggtg ggcacctgat tcatacttaa gcttagagta tacagactga cctgaaacca
     9361 tagcaaccac ttctttaaaa ccaccgacac cattcataga ggcttccatg acttcaaagc
     9421 gccaaccttg ggcttccgca tacttttggt acatagttag caaatctcca gcgaaaagtg
     9481 ccgcttcgtc tccaccagct gctccacgga tttcaaggat gatattcttg tcatcgtttg
     9541 gatcctttgg aaggagcaaa attttcagtt tttcttcata ttcttctttt tcagccttgg
     9601 catctttgag ttcttgcttg gccatttctt ccaagtccgc atctccgcct gattccttaa
     9661 tcatctcttc ggcatcgacg atattttgaa ggacttgttt atactcacgg taggctatta
     9721 cggtgtcacg attggaagct tcttcttttg aaagctccat aaaacgcttg gtgtctgaaa
     9781 cgacatcagg gtcactcagc aattctccta gttcttcata acggtcttct acagcttgta
     9841 gttgatcata gatgttcatt ttttctcctt atttctcaat tgttaaatca tagattgcta
     9901 ctacttcatt ctcggatatt tccccagttt ctttaaatcc ataactgaga taacaaaatc
     9961 ttgcctgttc attttctggt tcataagaca accaaagttt attgcttaaa cctgctggcg
    10021 ctgttcgaac atagtctagt actttatcca taattggttt aaaatatcct tgattttgaa
    10081 aattcttatc aatcataaaa caaaatagta aataatttcc actactaatt acgatctttt
    10141 tatcataagc tatcatcaca aaacctataa ttacatcatt atcataaact gccaatggag
    10201 ctacaaaatc tccattttta gtgtagacgt atgcttcagc taaactaatt gcgttggttg
    10261 caatgaattg tttttgatat tccttgacat ccaaatttaa aacatcaaaa taattttcca
    10321 ttgtaacatc tcttagttca attgtcatag ttttgctcct tgttagaggt tatcattggc
    10381 gcaaaataat gtttacggca aaccgagata taggtttcat taccaccaat ctggatctgt
    10441 tctccatcgt aaacgggcag tccatcctgt gttcgcaaca ccatggtcgc ctttttcttg
    10501 caatactgac agatggtctt gatttcgtca atcttgtctg ctaaaagcaa gagatatttg
    10561 gaaccttcga acaattcatt gcgaaagtca tttttcaaac caaaagccat gatgggtatg
    10621 tctaactcgt ccacaacacg agctaggtcg taaacatggt ggcgtttaag aaactgggct
    10681 tcatcgacca aaacacagta aggtttttct ggtaggtctc ggatatagcc aaagatatcc
    10741 gttgtttcct caatcgcaag ggcagggcgt ttcatgccaa ttcgactcga cacatagcca
    10801 acaccgtcac gcgtatccag agccgaggtc ataatgacaa caccttttcc ttgctcctca
    10861 tagttatagg ccaccttgag aatctcgatt gtctttccag agttcatggt cccataacga
    10921 taatacaact gtgccatgtt tcttgcttca cgtccatttc taaatttttg ctacattcta
    10981 gtatatcata attttcttaa gctttaaacg gcaaaatgtg gtaaaataga agaaatcaaa
    11041 aactagtgga ggaagctatt atgccatttg tacgcatcga tttatttgaa ggacgcacgc
    11101 tcgagcaaaa gaaagctctt gctaaggaag taacggaagc ggttgttcgc aacactggag
    11161 cacctcaatc tgctgtccat gtcatcatca acgacatgcc agaaggaact tacttcccac
    11221 aaggggaaat gcgtaccaaa taagctagct taagcagaat tgcttaggct ttttcaatct
    11281 ccaagtagca ttcattgaag aaatatccta aatttgttac aatttgaaaa gaaacttgga
    11341 gaatttccaa gaaaatagct attaattaaa ggaaacatta tgattacacg tgaatttgat
    11401 accatcgctg ctatctctac tccactaggt gaaggggcta ttggtattgt ccgcctgagc
    11461 ggaacagaca gttttgctat tgcgcaaaag atttttaaag gaaaagactt gaacaaggtt
    11521 gccagccaca ctctcaacta cggtcacatt attgatcctc tgactggtaa agtcatggac
    11581 gaggttatgg ttggggctat gaagtctcca aagaccttca ctcgtgagga tattatcgag
    11641 attaacaccc acggtggtat tgcggtgacc aatgagattc tccagctagc tatccgtgaa
    11701 ggagctcggt tggcagaacc tggtgaattt accaaacgtg cctttttaaa cggtcgcgta
    11761 gatttgacac aggccgaggc ggtgatggat atcatccgcg ccaagacaga caaggccatg
    11821 aacatcgcgg tcaaacaact tgatggttcc ctttctgatc ttatcaataa tatccgtcaa
    11881 gaaatcctta acacacttgc ccaagttgag gtcaatatcg actatcctga gtatgacgat
    11941 gttgaggaag ccactactgc tgttgtccga gagaagacaa tggagtttga gcaattacta
    12001 accaagctcc ttaggacagc acgtcgtggt aaaattcttc gtgaaggaat ttcaacggct
    12061 atcattggac gtcccaacgt tgggaaatca agccttctca acaacctctt gcgtgaggac
    12121 aaggctatcg taaccgatat cgctgggaca acacgagatg tcatcgaaga gtacgtcaac
    12181 atcaatggtg tacctctcaa attgattgat acagctggta ttcgtgaaac ggatgatata
    12241 gtggaacaaa tcggtgttga gcgttcgaaa aaagccctca aggaagccaa cttggttcta
    12301 ctagtgctaa atgccagtga accactgact gcgcaagaca gacaacttct tgaaattagc
    12361 caagatacca atcgcattat tctacttaat aaaaccgacc tgccagaaac gattgaaact
    12421 tcgaaactac ctgaagacgt tatccgtatt tcagtcctta aaaaccaaaa catcgacaag
    12481 attgaagagc gaatcaacaa cctcttcttt gaaaatgctg gcttgattga gcaagatgct
    12541 acttacttgt caaacgcccg tcacatttcc ctgattgaaa aagcagttga aagcctacaa
    12601 gccgttaatc aaggtcttga gctggggatg ccagttgatt tgcttcaagt tgacttgact
    12661 cgtacttggg aaatcctcgg agaaatcact ggggatgctg ctccagatga actcatcacc
    12721 caactcttta gccaattctg tttaggaaaa taagaaaaat ccatgatcct tcattcggtc
    12781 atggatttta ttgtctttat tagtaatctg gtcttaagac ccctgttaca gttgccttag
    12841 ttgcttcgta gtcgccatct acgacaacct tgataatgcg tttggcatct tcttctggtg
    12901 ctggaacaag aggtagacga gtgggtccag cttcaaatcc catatagtta agaattgcct
    12961 taactggagc aggacttgga taagagaaga gagcattaac cttaggaatg aatttacgct
    13021 gaattgctgc ggctttcttc atatcgcttt ctgcaatggc agtaaacatc tcgtgcattt
    13081 catccccatt tgtatgagag gcaacagaaa taaccccatc cgccccaagg ttcatggcat
    13141 ggaaagcatc tccatcctca cctgtataaa tcaagaactc ttcaggcttg tgctcaatca
    13201 agtaagccat attagccaag ctagtacatt ctttgacacc gataatattt ggatggtcag
    13261 ccaagcgaag catggtttct ggagtcaatt cgacaactac acgccctgga atgttataga
    13321 taataattgg taggtcagaa gcatctgcaa tagtcttaaa gtgctgatac atcccttctt
    13381 gagaaggttt gttgtagtaa ggaacaatag caagcccagc tgcgaaacca ccaaattccg
    13441 ctacttcttt gacaaactca atagagtcac gcgtatcatt agtacctaca cccgcaatca
    13501 aaggaacgcg tccattgaca accttttgta cagccgcaaa caactccaac tcctcatcgt
    13561 gggtcaaagt tggactctca gcagtcgttc ctgcgagaag aattccatcc gtatgatggg
    13621 ccaataaatg ctcaatcaag gctggaatag catcaaagtt aatagaacca tcctcatgaa
    13681 agggggtaat aaaggctgta atgattttac attcttttaa atcttgataa gacatgaaaa
    13741 cacctctcta tttcaaagaa ggagttcatc tgaactccta aacgatatga ctattttaat
    13801 tcaaatttca attcggctgt tggacgaacc aatccacgtt catgaagagt ttcagcaatc
    13861 tgaactgagt tccaagcagc acctttgaga aggttatctg aaacaaccca catgtgaatt
    13921 cctttttctg catccaagtc tttacggata cgaccaacaa aggtatcacg cgaaccaact
    13981 gcattgatag cttgaggata gatttgatga gctacatcat cttcaagaac agcacctggg
    14041 aaggctgcga tagctgcttt tacttcttcg attggagcca cttcttttgt ttcgatataa
    14101 acagactcag agtgagctga caagactgga atacgcacac atgttgcaga tactgcaatg
    14161 ctatcatctt ccataatttt cttagtttcc ttggtcatct tcatctcttc gtacgtgtaa
    14221 tcattatcag tgaaaacatc aatttgtgga agagcgttaa aggcgatagg ataatgtttc
    14281 ttgtcaccac ctgaaggcaa aatttccgca tgcaaatcac atggtttcac accatcattc
    14341 aagacttcac gaagttcacg ttgtgtctca agaattgctc ccataccagc acctgaaacg
    14401 gcttgataag ttgaaacaat gatacggtcc aagccccatt tttggcgaac cggctcaaga
    14461 gccaccatca tttggattgt tgaacaatta gggcaggcaa tgattccgtt gtgggcatca
    14521 agtgcatgag cattgacctc tggaacaacc aaaggaacat ctggattttg acggaaataa
    14581 gatgtattat ccactactac cacgccagct tttactgcgt atggtgcata cttagctgat
    14641 gtagaactac ctgctgaaaa gagagcaata tcaactcctt caaaagctgt ttcagtcgtt
    14701 tcttcaattg taatatcttg atctttaaat ttcaatgact tacctgctga acgtgcagaa
    14761 gcaaggtaac ggattttatc gattggaagt gttgattctt ccaacatttt tatcatctga
    14821 gcaccgacag cacctgtcgc gccgactaca gcaactgtat atcccataaa taacctcttt
    14881 cggaattttc taaaaatttc tataatagaa gtattatact actttttcca tgaattgcaa
    14941 agctttttca tcattttttg gaaaataaaa atcccagtcg ctagactagg gactaagagg
    15001 catcttcatg tgatgagcag gttcacacaa ctcatcaagg tccgctcctg cgttatgacc
    15061 tccttatgct caatagtagt ccgaagacta cctatcgact catcgcatat tctatattac
    15121 tagagatact tgattttgtc aataagaaat tttttcgatc gagtataaca aaaaactctc
    15181 gtattcaaga gtttccctat acatatcatg ctaattgccg ggatcgaacc ggcgacctca
    15241 tccttaccat ggatgcgctc tgccaactga gctaaatcag cttacttaag aagtatacta
    15301 tattcagaaa aacttgtcaa gtttccttag aaattttcca taggaaaaag ccaggtaaga
    15361 actacctagc ttatcttctt ctatttactt aaatcaattc gacgaccaat tttaccaata
    15421 ataatcgccc caataatcaa tgaagcaaat tcaccgattc ctgttgtaaa ccaagtaagg
    15481 aagaatggta attctgctac aatatttaac tctgcagcga tagtaaacat ggaaattgaa
    15541 aagaggattg aaaagaagaa atgatctttt tgaatcaatc cgttaaagag gtaatccttg
    15601 ctatattttg caaaaagcca aacacctaaa ctgaggaata ctaaggttga accaccacca
    15661 acaaagacat ctagcagtcc gaagctaaag aaattagcaa tcatacaacc gatggtaact
    15721 ccgatgatgt acttaggatt gtaaaaagcc ataaagttca tcatttctga aatacgaaac
    15781 tgataagcac catagctgat ggcatttagg ggcggtgtga cagtcaaaac gacgtagata
    15841 gcagcgacga ttgcaatatc tgcaacatca cgaatagtta attttttcat cttttctcct
    15901 ttggcggttg cccgcgtgta atatgcttgg tgaaagaagc taagcaccaa gggttgcttt
    15961 attcaaccct actagtatag cacaatagcc tgctttatgc tatacttaac acatgaaaat
    16021 tcctattcaa aaatttttta acaatgaaat cttagcctat ctcttttttg gccttgcgac
    16081 aactctagtt tcgattctct cacgactagt catttatcaa ctaagtcatc aggaactcct
    16141 ggctactgcc ctagcaaata ttatcggtat cctatttgcc tttatcacaa atgatacgat
    16201 tgtatttaag caaaaaaaga aaaatagact tatccgttta gtgaaatttt ctcttgctcg
    16261 cctttctact tttctgttag acttgttttt aacttttctc tttgtaaccc aatttcctca
    16321 cattataggg caattcgtaa ctgaaaacat tgataagata aatgctattg aaacaataat
    16381 tgcacaaata ttcattatta tcatcaatta tatattgagc aaggcctata tttttagaaa
    16441 ataatgctcc atttatgagc cttttaattg ccttctataa tgatttagga tacaatgaaa
    16501 cacgaaacat tgaaaggaaa acagtatgtt aaaaaatcta aaatcgttct tgcttcgagg
    16561 aaatgttatt gaccttgctg tcggtgttgt aattgcctct gcttttggtg ctatcgttac
    16621 ttcacttgta aacgacatta tcactcctct tattttaaat cccgctttga aagctgctaa
    16681 agttgaacgt atcgctcaac tttcttggca tggagtcggc tatggtaact tcttaagtgc
    16741 tattatcaat tttatctttg tgggtaccgc cctcttcttt attatcaagg gcattgaaaa
    16801 agcacagaaa ctgactggca taaagaaaga aaaaactgcc gaaaaaaaac caaccgaatt
    16861 ggaagtcctt caagaaataa aagctctcct tgagaaaaaa taatcgatta aaaggatcta
    16921 gcgcaaagct aaatcctttt ttctttactc tttgggtaac ttgcctgctt tttcaagcat
    16981 ttttttgatc agataaggca tcttaacatt ctcccgccct tttttctcaa tcagtttttt
    17041 cacaaattct ggcatttgta aatcttcaga ttcagctaaa atgtttttcg tctcgtctga
    17101 aggaactaac tcatcaaagg tctcttcttc tgggagaaat tccttaaact cttgattttc
    17161 attgactcta actgtattga ccaaagcatc aatcaaacga gaatctgtat ttggcattgg
    17221 tggacgatgg tagtttaccc caaattcctg gcataagtca taacattcta catcattgtc
    17281 aaacaagacc tcaatatgct cactgatgaa actaataggt acaaaaatat aatggtctgg
    17341 atgttctgtc tgttctctga gatactccaa aacatctggt ttaatccatg gaataccaat
    17401 atcactctca ctctgccaag tgttggtata ttgttctgaa ctcaagccca gtttttcagc
    17461 gactagcttg ctattttcga aaatttggtc tatataagga tcaccaaagt ccaaggcaaa
    17521 aatgggcaca ctatgggctg aaaagatgac tttaaagctg tcttgcttta cttcttcttt
    17581 taaaatctta gcaatttcat ctgcccaata gtttaagagc acttcttcct gataccagtc
    17641 cttaatgacc aaaaattgaa tttgtttgct ttctaaaaat ttttcatagc ccatgacaga
    17701 gtagaaagaa taatggggct ccaaaatcaa gcagatacat tcttcaacac catcagtttc
    17761 catctgcttg atcacgtctg gaataaaggg acgagaaaat ttgttggcaa agtagatacc
    17821 gtactcctcc cctaaacgtt ctttgactaa attgacctcc tcacgtgtaa tccgctgcaa
    17881 aggcgtccca ccgatacgaa tatagttgtc atagagagtc tggatttcgt ggtcttgggg
    17941 tctaactcca cgacgaatgt ttgtaaagaa ttctgctact ccttcaaaac taatctcctc
    18001 tggagatcca aaggtcatca ttaatatggc ttttttcatg ttatcatcct tatgatatta
    18061 ttttctctat ccattctatc atgaaagaaa aaaatagtaa acgtttccta cgtctactat
    18121 ttcttttgct cttttgtttt tttatctcgt cttataatta ggatgataag gacaagaagt
    18181 aagaggacga taataaggag tagaaaggct agaatgtaaa tccaatgact gggaattccg
    18241 tgatcgaaat accgtgttcc tactgcttcc ccactttcat cctgtgctac tttcaccggt
    18301 gcatccgtta ttttagctaa aaggatatgt cgtccattag ttatgttaag gaaacaggtg
    18361 cttaataaaa caatcttgtc cgttgaggtc aaggaaacat ctcgcttgta cttggcttta
    18421 cttagcagat attgatagta agcctggtgt tcctcatcct tggaactcaa ggttcgataa
    18481 atctccgtgt cataggcatc cacttctaaa atcccaaaaa tttcaagacc acgttctcga
    18541 ccattgtagt agatagaacc gtagcgatgc tggtcgaaga attccttatc agcaaatttc
    18601 ttaatctcac cgaacatagc ccctgaagcc atagagtgtc cgtagatgat cgtattaaaa
    18661 tcagtaaagt tgggattaaa gcgatagtcg agaaaaattg atcccattat cgtataatcg
    18721 ccaaaggcat tgcggtcaag gtatttgaca ttatcctgac tttgtagaag cggatagtct
    18781 accttggtcc catcaaggct aatccaaccg caaacatctt tgttcaagtg ctgtagggtt
    18841 tcaaaacctg tgctcgaagc atccttttca ataggattat agtgatcata gtcacttgct
    18901 tctactactc tctgccaact aaaaagagct acaaaaacac agaagaatac cagaaatacg
    18961 tttttaaatc gcgctctttt ttgaaccgtc atcagcactc ctttctatgc gagatttctt
    19021 aaaaggaaag gaggcgggac aaaaccgcct cttttctatt cacccttagt cagtaaaagg
    19081 gtctgcttct tgcatttttt ttactctctc ttctacgacg taggatcaag tagaggacaa
    19141 ggagtaagaa aatcaagagc aagaacaata caaacaagat aaggtaccaa atccatagtg
    19201 ggattgatga gaggaaacgt ccaagagacg agtcatcaaa gacactgtat ggaaatggtt
    19261 ttgatttttt tgtatggaaa gtatttttag ggacggtgtc tgtaatcttt gcgactacga
    19321 tatgacgacc attggtcaca tcgagaaaac aggtactgag taggatgata cgatcactcg
    19381 gtgagagtga gatatcccgc ttgtgcatgg cgactgagag caggtggtct agataggcct
    19441 gctggcggtc ctcaccctgt attcctggat catagatgtt aaagtcatag gcatcaacct
    19501 ccaacatctc aaagatctcg agcccttttt ccacaccatt gtagtatata ctaccgtaac
    19561 gatgctggtc aaaaaattcc tgatcagcaa acttagccac atcaccaaac atgaccccat
    19621 tttctacgtg gtgcccgtag ataatggtat taaagtcttc gaacttagga ttatttcgtg
    19681 catcgagaaa gatagcgcct gtcgctgcaa actcaccttt ggagtccttg ttgagatact
    19741 tttcattgtc cttggcttgg actaagggat agtcgatatt ggtgccatag acattgatcc
    19801 aaccgaggac ttcgggattg agttcttgga gtttgctgaa gcctgaaaaa ctggccagct
    19861 catcctgttg cgtcgtgaca ggtcgataag cttcgtactc acttgacgaa gctaaggagt
    19921 agacttggtt ggaatcccaa agggcgtaga aaccaaagag aaagatcaaa gctgcaaaaa
    19981 tgagcagcaa gtgattgatc accccatcca cagcaagaac gagacgccta gacagactct
    20041 tttttggttt ctcacgcttg gttttcatca tctgccccca gccgtttagg cttctctacg
    20101 ttttttagac aagacaacaa atccagccaa accaagacca atcatcaaaa tgaatggaag
    20161 gttatcaatc aagagaccag taggagtaac gtcgtcgatt ttgttagtaa ctttgttgtc
    20221 gtttttcttt tcacctatga ggatatctgt taatgtaaaa tctacatttt tttgtccttg
    20281 agatgtttgt tctgcaccat ttgtagtata aattgatgaa tctgtataac ctgctactcc
    20341 agtttcagtt actgtatatt tagaacctgc tggtagttgt tcaactgtaa atgtttcacc
    20401 atctttaaga gtaaaattgt actcaactgt atctgctggg gtcactactg ccaacacctc
    20461 tgacttagat ccatgtttta ctataatatt cgtaacaggg gtttctgctg ttttatttgt
    20521 acttggaagt tgaatcttga tatggaattg gaaatctctt gttttatccc ctgaagctcc
    20581 atcaactttt ttagtaattg ttaatgcttt cgcattgggg tctacttgac tcggatcatc
    20641 aggattaggc tccttacttg cgtctttggt atatgtgtta tcaaataaat tataaacgcc
    20701 ttgttcactt ggttctactt taggggcgtt agatttatta ttttccttaa agtatactga
    20761 tgaaatatag acaccaccat ttactttatt cttaacaata acgtgcattt catatgtacg
    20821 tttgtcgtat ctcatggcat caattgtttt accatttttg gtaatcgcct gccatccagt
    20881 ttttgcttcc gctacatcat aaacgtattc accagcatgg ccataagcaa ctcccgaaaa
    20941 aatgtcttct gttgcttttt gaatcttatc agcagttggg tgatcatttt tattgtattc
    21001 tacatttcta tctggaattg caactccggt ttgatatggc gcaccgttag aagattgtcc
    21061 tgttttttct gtaaacttaa atgtaaatgt cgctgttggt gttgttattc cctctgcaat
    21121 attcaacgtt ttattaatct tcacaacagc attattttca ccatttgctt tggttattgc
    21181 tgaattatca tccgcaaaag tcgggacacc tctgaatacg gacaaagcgg ttatagctgc
    21241 aatgcttgca gtgaatagct ttttaaagaa tgtttttttc atgattattt cttttgtttt
    21301 tttattttct tttttcatta tgatcatcaa aagcctcgtc ttctaatgac tgttacaact
    21361 ttgccttgag tatcctgtat agggatggtt ccaaaagcac gactgtctac agccgttgtt
    21421 cgattgtccc cgaggacaaa aagttgtcct gctgggactt tcatcgggaa ggttgcccct
    21481 tccttataga gcagcgtttc tttgtagata tcttgctctt gttgaggaga accgttgatg
    21541 atgagaccat tttcgtttat atcgattgta cttccttcgg ttgctatgac acgcgccact
    21601 ctttccttac ctttataact atagactagc aaatcaccaa tcgaatagcg tttatccaac
    21661 ctataataga cgaccaagtc gccatctttt aaggcgggct tcatgccatc gtcattgtat
    21721 cttaataatc caaagacgaa aaagtaaagg atggctagta caaatccaac catcagaagt
    21781 ttactgacta agtaaaggat atctccccag acactcggcg gagacttatc ccgattgact
    21841 tgtgttactg gtttcttatg tttcttttta agcagcatca cttcctccta ttcaccacaa
    21901 ggtgaccaag taagatgata aagaagatcc ctcctagagg aagaacgact ccaagcacga
    21961 gagtgctact caagaagtca attcccgttt caggtacgct gtttttatta ttcgtgactg
    22021 tcgcagactt atttgcatca agagttcctt cttttttatc ataggacacc tgatacccac
    22081 gagacgaact tgcttcttct tcgatactat aacgagcatt tagaggaagg tcgagaatct
    22141 tgatggtttt atctttcttt agatcaactg tcgccttacc attggtgaat tgtagcgttg
    22201 ttttttgatt atttactatt gcactatacg atccattcaa tggtttattt tgcgcatcct
    22261 ttacgttaat ggtaatctta aaggattgca gaagattagc aaaagcacct gtaacttttt
    22321 ttatgactga aagtgtcgga agtctgtggt tggtgacgat tgtttgaaca tcctctgaca
    22381 aagtcccctc ttgtttttca taggtgacat gatatcccgt tctagagttc tctacttctt
    22441 ccaccttata gtgggtatca cgaggcagat aactgagggc agtttcctga ctatttttga
    22501 gagaaatctg tgctttcccg ttagtcactg ttgtattccc aaacttgccg ttaatcggct
    22561 tgccatcctt atctgaaagg gtaacattaa ttgtgaaaga tttattaggt gattgttcac
    22621 cttctaggat tttctttacg gtgagacttg gaagctgtcg gtaaataact ttgaaggatg
    22681 gtttctcttt cgtacctgtc ttttgaactt cgactgtgta tcccggagcg tctggtgctt
    22741 tcagttcgta gtcatatccc ttagctacct ttgcaaaact agtattttca gtaaaactat
    22801 tcgtttgaac tggactagtg acctttcgat aggaatcctt tatacttcca tctttctttt
    22861 ggtttaagtt taattcgaca ctaggtggac gatttgctga tggatttgat tttccatcca
    22921 cacctttcca ctcaatctct acaggaaccg tcaatggatc tgacggcttg aaagtgggct
    22981 tctcagaata gtcttttatt ttggtacgtg aggtcccaat accataggaa taggcaactt
    23041 ttgccccctt gttggagtag agtttagtag catcggcttc ttcggcatca tcactagtaa
    23101 gtgtcttatc acccgcaatc gcatcaaatg cctcttggct agaggtgaca gtaaacttga
    23161 gaacgtactt ggcgtcatcc tctaaagtgt aactcggatt aaacttggct gttacttcca
    23221 ctaatccctg ttcgttcttc ttagtttcaa tcgtaacttg attgtcattc agttcttgct
    23281 cgttaccatc cttgattttg acgacacgaa ggtgtgaagc atcaccaggt aacagctgca
    23341 cgtacttgga caagacatct gatatagtta catggtgtac gcctagaggt agaattttat
    23401 ctgtgatttc tttgaatttt tgttgcaagt cattttcatt attggcagaa aatatttcgt
    23461 tggggattcc agaattataa ccactgatat atcctttaag agatgtgata ctatcgtttg
    23521 aacctatata tctgaatttg attgaataaa agccatctat ttttggagct attaaactag
    23581 atatattcag cattcctctc tctaaaccag aggtaaacca atatggagta tcaatcatac
    23641 gtcccacatt tggattagaa taatagttat atattgttct cccactatta gactcgtaat
    23701 acatattagc ttcgccatct gacagcagaa taactacttt ttttgcccca gcccttgcac
    23761 tttgcaacaa tctttgagct tcagttaacc cagcatttat atttgtccca gtgccaatgc
    23821 ccgcgtccat accataagaa cgactagagt cagcaattgt taacgaacta acaatatttt
    23881 ttgagctatt agaatccgtg ctccaagata ctaaagtttt agcatcatca tatgaagaga
    23941 tatttgaata ccaaccagct caatttggcc aagttccata ttgataactc agataatatt
    24001 cattataata acggtcatta tactgattat caatctttcc ggcaaaacca actatagaca
    24061 gacggttttg ggaattagaa agaattgtat caatgagccc ctgacgacca ttcacacctt
    24121 tcagtgtatg ttttagtgct tcaatcctac taatgtatcg tctactagag taagaccaca
    24181 catctcgctc ttccatactc cctgaaagat cggcaaccaa gactacatcc aagggttctg
    24241 actgggtctc cgttcccagt ttagatgtga tatccagtga caactcatac tggtcttttt
    24301 gccctgatat cggagtaatc gttttgtgca gagttgtctg aggttcagtt attgaatctg
    24361 cacgtaaaga attaattggt gcacacaaaa aaagaatagc gagaaagata actaaaatac
    24421 tggtaaaata ttgaatcttc ttaaaatcat attgaacgtt catgctatct cccttgctag
    24481 aatatgtttt aatctgatac tatataaatc tgagact
//
LOCUS       DAVLHM010000031        24285 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLHM010000031 DAVLHM010000000
VERSION     DAVLHM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24285
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.031"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(68..1843)
                     /gene="spxB"
                     /locus_tag="VXE45_001421"
     CDS             complement(68..1843)
                     /gene="spxB"
                     /locus_tag="VXE45_001421"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0789441.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2050..4293)
                     /locus_tag="VXE45_001422"
     CDS             complement(2050..4293)
                     /locus_tag="VXE45_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0789442.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4303..4674)
                     /locus_tag="VXE45_001423"
     CDS             complement(4303..4674)
                     /locus_tag="VXE45_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0789443.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(4685..5080)
                     /locus_tag="VXE45_001424"
     CDS             complement(4685..5080)
                     /locus_tag="VXE45_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0789444.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5264..5362
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5446..6237
                     /gene="thiD"
                     /locus_tag="VXE45_001425"
     CDS             5446..6237
                     /gene="thiD"
                     /locus_tag="VXE45_001425"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0789445.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQAKDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6446..7078)
                     /locus_tag="VXE45_001426"
     CDS             complement(6446..7078)
                     /locus_tag="VXE45_001426"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0789446.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7071..7874)
                     /locus_tag="VXE45_001427"
     CDS             complement(7071..7874)
                     /locus_tag="VXE45_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0789447.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLNYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            complement(7874..8398)
                     /gene="thiW"
                     /locus_tag="VXE45_001428"
     CDS             complement(7874..8398)
                     /gene="thiW"
                     /locus_tag="VXE45_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0789448.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(8403..9095)
                     /gene="tenA"
                     /locus_tag="VXE45_001429"
     CDS             complement(8403..9095)
                     /gene="tenA"
                     /locus_tag="VXE45_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0789449.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9106..9756)
                     /locus_tag="VXE45_001430"
     CDS             complement(9106..9756)
                     /locus_tag="VXE45_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0789450.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(9758..11143)
                     /locus_tag="VXE45_001431"
     CDS             complement(9758..11143)
                     /locus_tag="VXE45_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789451.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11144..11704)
                     /locus_tag="VXE45_001432"
     CDS             complement(11144..11704)
                     /locus_tag="VXE45_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0789452.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(11966..12054)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12263..12892)
                     /locus_tag="VXE45_001433"
     CDS             complement(12263..12892)
                     /locus_tag="VXE45_001433"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0789453.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGAITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(12894..13676)
                     /gene="thiM"
                     /locus_tag="VXE45_001434"
     CDS             complement(12894..13676)
                     /gene="thiM"
                     /locus_tag="VXE45_001434"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0789454.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            13767..13853
                     /locus_tag="VXE45_001435"
                     /pseudo
     CDS             13767..13853
                     /locus_tag="VXE45_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14003..14671)
                     /locus_tag="VXE45_001436"
     CDS             complement(14003..14671)
                     /locus_tag="VXE45_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0789455.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(14886..14974)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15228..16364)
                     /gene="lctO"
                     /locus_tag="VXE45_001437"
     CDS             complement(15228..16364)
                     /gene="lctO"
                     /locus_tag="VXE45_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0789456.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(16989..18479)
                     /gene="lysS"
                     /locus_tag="VXE45_001438"
     CDS             complement(16989..18479)
                     /gene="lysS"
                     /locus_tag="VXE45_001438"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0789457.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(18607..18753)
                     /locus_tag="VXE45_001439"
     CDS             complement(18607..18753)
                     /locus_tag="VXE45_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0789458.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            18786..19703
                     /locus_tag="VXE45_001440"
     CDS             18786..19703
                     /locus_tag="VXE45_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0789459.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFG
                     LARNFNINISGETSVIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTTSFW
                     IYGTILILYFAVCYPISKLSTHLEKHWRN"
     gene            19704..20462
                     /locus_tag="VXE45_001441"
                     /pseudo
     CDS             19704..20462
                     /locus_tag="VXE45_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            20474..21334
                     /locus_tag="VXE45_001442"
     CDS             20474..21334
                     /locus_tag="VXE45_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0789460.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(21414..22061)
                     /locus_tag="VXE45_001443"
     CDS             complement(21414..22061)
                     /locus_tag="VXE45_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789461.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKPGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(22058..22756)
                     /locus_tag="VXE45_001444"
     CDS             complement(22058..22756)
                     /locus_tag="VXE45_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789462.1"
                     /translation="MGKLSSYMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(22766..23518)
                     /locus_tag="VXE45_001445"
     CDS             complement(22766..23518)
                     /locus_tag="VXE45_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789463.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(23518..24282)
                     /locus_tag="VXE45_001446"
     CDS             complement(23518..24282)
                     /locus_tag="VXE45_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789464.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
BASE COUNT         7512 a         5257 c         4379 g         7137 t
ORIGIN      
        1 agttctgctc tatgaaaatc aaagaataaa gtctacaagt ttcatatttg attttcggcg
       61 agaggaatta tttaattgcg cgtgattgca atccttcttc ttccaagaag agacggaatg
      121 gtacgagttc ttctgcttcg tatttttcct tgaaggcttt gatagcttct tctgagtgaa
      181 gttttggatc caattcaagt acttctactg gaagtggacg gtgttgagtg atgcgagcat
      241 cgatgacaac agttttacct tctttgttca atttaacagc ttctgcaaca actgcatcga
      301 tgtcttcgat acggtcaact gtgaatccaa cagctccttg agcttccgca attttagcgt
      361 agtcagcgtt tgtgaagtct acaccaaaca agtgtttgtt tgtatcttcg tatttgttct
      421 tgatgaagcc gtactcagca tttgagaaga caaggttgat aactggaagg tcgtattgaa
      481 cgtttgtgat aacgtctggg tagcacatgt tgaatgctcc gtcacccatg atgttccata
      541 cttggcgatc tggattgtct ttcttagcag cgataccacc aggaagggca atacccattg
      601 tcgcaaagag tggagatgta cgccacatgt tcttaggtgt catgtgaagg tgacgagtag
      661 atgtttgagt agtgttacct acgtcgattg agtagatagc gtcttgatca gcatgtttgt
      721 tgattgcatt gtaaacttga tacaattgca attcaccctc agttttacct tcgagtttgt
      781 tcatgtaatc acgccagttt tggttgttct taacgtttgc acgccaccat ggagttgatt
      841 caactgggtt tactttgtca aggatagctt tagctgcttg accagcatca ccaaggattg
      901 aagcgtcaag agcatgacgt ttaccaagtt tgtaagggtc gatatcgact tggataaatt
      961 tttcagtgtt cttgaatgct tcgtaaactt cagcgaatgg gaagtttgaa ccaaggaaaa
     1021 gaactgtgtc tgcttcaaag accacttcgt tggctggttt ccaaccaaca cggtaagcag
     1081 aacctgtcaa accttcatag ttccattcga aagcttcaaa gtttttacca gttgtgatga
     1141 ttggtgcttt gattttacgt gacaattcag taatcacttc accagcttta acaccaccaa
     1201 atccagcata gataactggg cgttcagcat tgttcaagat ttcaacagct ttgtcgattt
     1261 caacttcgtt caaagcagga gcgatgaatg agcgttcgta tgaacctgaa ccgtagtatg
     1321 agttttcatc gatttcttgg aaaccgaagt ttactggaat ttcaacaaca gctggacctt
     1381 ttttagaaac tgcagcacgg caggcttcgt caattacttt tggcaattgc tcagcgtaag
     1441 ctacacgttt gttgtaaaca gcgataccgt tgtacattgg gttttgatta agctcttgga
     1501 aagcatccat gttcaattcg ttaactggac gtgatccaag gatcgctagg aatggagtgt
     1561 tatccatagc tgcatcgtaa acaccgttaa tcaagtgagt cgcacctgga ccacctgaac
     1621 caactgcaac cccgattgag ccgccgaatt tagcttgcat aaccgctgca agagcacctg
     1681 tctcttcgtg gcgaacttgt aagaaacgga tatctttgtc ttcagccaaa gcatccatca
     1741 atgagctgag tgttcctgat gggataccgt agattgtatc tacgccccat gttttcaata
     1801 cgttaagcat tgctgcagat gcagtaattt tcccttgagt cataatgata actctccttc
     1861 aattttttta aacttggaga atacgattac atagaattgg aaacgttctc caaattttta
     1921 ctattccact gtatcatatt tatgctgact tttctaaaaa tctgctcaaa actctctatt
     1981 ctctattcta atacagtttt gaaagtgttg tcgtttctgt tttataacaa agaaatctag
     2041 tcattacttt tagtctattt tactaaaatt taacagaagg gaactggtca gaacagatac
     2101 agaactaaag gccatggcta gacctgccaa ttctgggttg agagccagtc caacacctga
     2161 aaagactcct gctgcaatcg gaattccgac aacattgtag ataaaagccc agaaaagatt
     2221 gagtagaatt cgatgaaagg ttttcttact catatcaaag gcacgaacca ctcctaaaag
     2281 attattggtt gtcaacacca aatctgctga ctcgatggcg atatctgttc cagcacccat
     2341 agcaattccc acatctgcta cactaagggc aggagcgtca ttgataccgt ccccaacaaa
     2401 ggctactttc cctgactgtt gcagtttatg gatttcatgg gctttttctt ctggcaagac
     2461 gcctgcaatg acctcttcaa ttccgatttg atctgcaata gcacgcgcca caccagcatt
     2521 gtctcctgtc agcatgactg ttcggagacc acgttttttt agctgactga tggctagctt
     2581 agcattttcc ttaggaatat cttgcaaagc aagcaagcct ttgatttcat tgtcaacagc
     2641 taagaacaca actgtcttag cttctttttc tagttcttct agtttatctt gataagtatt
     2701 agaaatatcc atgccatcca gcattttagc atttccaagt aaaacttgtt ttccattgat
     2761 tcgccctgaa acacctttcc cgtgcaaggt ctgaaaattt tcaacagttt gaaactcaag
     2821 tccagcttca ctcgctcgct taacgatagc ctcagccagt gggtgttgag aagcatcttc
     2881 caaggaggct gccaacccaa acacttctac ttcgtcgccg atgacatctg ttaccacagg
     2941 tttcccttcc gtcaaagtcc cggtcttatc aaagacaagg gtttgaactt tctggatttc
     3001 ctgtaagaca gttccatttt tgaggagaac ccccatcttg gcactacgtc ctgtccccac
     3061 cataagggct gtcggtgttg caagtcccaa ggcacaagga caggcgataa tcaaaaccgc
     3121 cactccgtag agaagagagg acacaaagct agctccaagc acaaccacac tatccctgag
     3181 caagacgaac caaacccaaa aggtcatgat tcctaaaatg acaactactg ggacaaaaat
     3241 ccctgaaatc ttatccgtca agtcctgaat cggcgcacga cttgtctgag ctttcttcac
     3301 aaaatccaca atctgagcca aaacagtctc tgagccaact ttttctgctc taaagacaag
     3361 cgttccacta tgattgatgg ttgagccaat gacagtatct ccaactgtct tgtccacagg
     3421 cagactctca cctgtcacca tggattcgtc aatactagag acaccttcta ctacgacacc
     3481 atcaacagca atcttttcac cgggacgcac tcgaatcagg tcgcctacct tgacttgttc
     3541 caaaggaact tggacataac tatcatcact caagacttct gcggttttag cttgcaagtc
     3601 cagtaatttc tccacagctt gggacgtatt ttttctcatt ttttcctcaa aaactgctcc
     3661 caaaagaacg aaaaagagga taaatccagc actttcgaag taaacaggga gaccagcaaa
     3721 gagagcaact aggctataga aataagccac tagagttccc agcgcaacca aggtatccat
     3781 gttggcattg tgctttttaa aactggccca agcactctgg atatatggct tacctgcaac
     3841 taacataata ggcgttgttg ctagaaaggt tccccaatgc atgacttgat gactaatgct
     3901 acctgtcaac atcccaatca tgagaatcac aagaggcaca gtaaagatac tagtaatcca
     3961 aaaacgttgc aggagagata gagattttcg agtcttctca acgactgtat agcttccctt
     4021 ttgcatcttc atgccacaag aaaattcatg tcgccctaat tcttgaggtg taaaacgaat
     4081 gactttctcc tcatctacgc cgattggttc caagatacct tcttcttcaa acagaatttc
     4141 cttataacag tttgaaggag tagcacgatg aaaggtaatc tcagctggaa ttcccttttg
     4201 aagctggata tgggctggat gatagccttt ttcagatcgg atacggattt tttgaatgcc
     4261 attttctaag cttgctttca caatttctgt catagtctcc acctactcta caatcatctt
     4321 gccgtgcatc atgttcatac cacaagcaaa gccaaattct ccagcctgtt caggcgtgat
     4381 ttccactaca tactcttccc ccattggcag gttcgtatgt acaccaaaat ctggaaaaac
     4441 aatttgatcc agacatggtg aaggatcctt gcggtcaaag acaatgcggg ctggcactga
     4501 tttcttgagg acaatcaact caggagtata gcctcccatg acttccactc gaatctcttg
     4561 gtatccgttt ttttgctggg ctttttgtcc agatttttca ggctttttga aaaaccaaaa
     4621 caagataaac gcgataaggg caatacaaat aatggttaca atactattta acatgacgtc
     4681 tcctttacat acaattacat cttacttctg ttacagcact tgatttcttc tctgaaatca
     4741 cagcttccaa gtcttccaag tcagtctgag taaattcaca ttctacaatc aagtcagcca
     4801 acaaattcct aatcctacgg gaacaaacct tgtctttgat atcttggaca agtaaatccc
     4861 gactttggtc tagagttaaa agggctgaat aaacaaagga cttgccttct tttttccgag
     4921 tcaaacactc tttctcaacc agacgagcca aaagtgtctg aaccgtggac ttggaccagt
     4981 caaaccgctc tgccaaaacc ctaatcaaat ctgtactggt ctgctccccc tgcatccaaa
     5041 taatcttcat gacctgccat tctgcatctg aaatctgcat taccatacct caaaaatcta
     5101 catttgtcaa ttacactcat cagtatactc ttaaaatcta catttgtcaa ttatagaaat
     5161 aatattttct tcgaaaaata gaattttaat catttgaaaa acgatttgca gtcaaatatt
     5221 actatataaa caataaaaat atgctatact aaagaaaaaa gaaaacaacc actaggggtg
     5281 cgtaaagctg agattaacga ctgttagatc cctctgactc aatctaggta atgctagctg
     5341 atggaagtgg aaatgataat ggggactagc agtcttctat tgcctttcta aaacagacta
     5401 gcttgttctt aagaatacaa acttcagttg gttgggaggt tttagatgac ttatttaccc
     5461 gttgctttga ccattgcagg gactgaccct agtggtggtg ctggcattat ggcagattta
     5521 aagtcattcc aagcgaaaga tgtctatgga atggctgttg taaccagtct tgtcgctcaa
     5581 aataccagag gtgttcagct aatcgagcac gtttctcctc aaatgttgaa agcccaattg
     5641 gagagtgtct tttctgatat tccacctcag gctgtaaaaa ctggaatgtt ggctactact
     5701 gaaatcatgg aaatcatcca accctatctt aaaaaactgg attgtcccta tgtccttgat
     5761 cctgttatgg ttgctacaag tggagatgcc ttgattgact caaatgctag agactatctc
     5821 aaaacaaact tactacctct agcaactatt attacgccaa atcttcctga agcagaagag
     5881 attgttggtt tttcaatcca tgaccccgaa gacatgcagc gtgctggtcg cctgatttta
     5941 aaagaatttg gtcctcagtc tgtggttatc aaaggcggac atctcaaagg tggtgctaaa
     6001 gatttcctct ttaccaagaa tgaacaattt gtctgggaaa gcccacgaat tcaaacctgt
     6061 cacacccatg gtactggatg tacctttgct gcagtgatta ctgctgaact agccaagggc
     6121 aagagtcttt accaggcagt tgataaggcc aaggccttta tcacaaaagc tattcaagat
     6181 gcccctcaac tcggtcatgg ttctggtcca gtcaaccata caacttttaa agattaagaa
     6241 aaaaactctc tagttcccac tttaagggaa ttagagagtt tttataccct tcgaaaatct
     6301 cttcaaacta cgtcagcttc catctgcaac ctcaaaacac tgttttgagc tgacttcgtc
     6361 agtcttatct aaaacctcaa ggcagtactt tgagcaacct gcgactagct ttctagttta
     6421 ctctttgatt ttcattgagt attaattagg aaagaatgtc atgcaacttt gttaaaaagg
     6481 cttgcgtttt tgcctcaata tcttctgctt gcatcaaatc acgtacaaca gctacaccag
     6541 ctatgccagt gcccataagc tgatcaatat tctccgaagt caagccgcca atagcaacta
     6601 ttggaatggc aaccgtttgg caaattgttt tcaaggttga aatcagggtg atgggtgcat
     6661 tttccttggt ggttgtcgga aaaatggctc ctgtccccaa gtaatctgca cctgatttct
     6721 ccgcttccag agctctttta accgttttag cggtgacacc gaggattttt tcaggaccca
     6781 agacttgtcg ggcaaccgaa actgggagtt cgtcatctcc aatatgcaga ccagcagcat
     6841 caaccgcaag acaaacatcc aaccgatcat cgattatcaa gggtacctga taggcatctg
     6901 ttatttcctt gacttgtttt gccagttgat aatattgatt ggttgtgaga tttttttctc
     6961 gcaattggac tatggtaacc cctgaacggc aggccgtctc aacttttgca agaaagcttt
     7021 ccacggaatc ttgatagcga ttggttacca gatatagtct aagtgcttct ctattcataa
     7081 gcctctcctt tgatggtatc tagccaattt tcatctcttc ttaggagcga aagctgattg
     7141 agtacttggt aacgaaattc ttccaatccc attccttgaa caactatttt ctcagcagcg
     7201 atattgagat aagagactgc taagcaagaa gcttcaaaac cagtctttcc ttggctgaga
     7261 aaaacggctg ttaaggctcc aaccaaatct cctgtccctg ttatccagtc taattcagta
     7321 cagccattct ccagtacagc gacctgattt ttcgaaacga tgaggtcctt ggggccagta
     7381 actaagaatg acataccagg ataggtctga caccagtctt tcaagacttg aagcaaatcc
     7441 tccgtttctt gatctttagc actcgcatcg accccaacgc cgtggtgctt taagccaaca
     7501 agacttcgaa tttctgacat gtttccttta atgaccgtag gtctatagtt taaaaggtct
     7561 ttaactaagc tcttacgaat ggatgaagtc gttacgccaa ccgcatctac taccatcggg
     7621 agagaagatt ggtttgcata cgaagctgcc atgcggattg ctttttcctt ctcagctgac
     7681 aaatgcccca aattgatgaa aagagcctga ctttgcttag taaaatcaag aacctcacgg
     7741 ggatcatctg ccatgacagg tttgcatccc agagccaaaa tcccatttgc cagcatctca
     7801 caagaaatct cattggtcat acagtgaatt agggaactag agcctatagg aaagggattt
     7861 gtaaattcct gcatcagtct atcctttcac taaagaaata tccctgcact tttttaaaga
     7921 attcctgctt gattaaaaat cgaaaggcaa taaaggaaat cgctgtacca atcaaggttg
     7981 ctccgaaaaa tcgaggcgtg tagataaacc agctaagctt agcagctgat cctgtaaaga
     8041 gtaccataac aggataggaa acaatggaac caataatacc tgttcccaca atttctccca
     8101 aggcagaaaa ataaaatttt cgaccgtact tataaaagag acctgccaga agggctccaa
     8161 aagtcgctcc tgtgagagct aaaggcggaa tcccttgagt cgtcatacgg ataaaggctg
     8221 tgactgtagc catggccaag gcataaacag gtcccatcat gattcccgct agaatattga
     8281 ctacactgga catcggtgcc attccctcaa ttcgaaagat aggtgtaagg actacatcaa
     8341 gggcaatcat catagataaa atggtcaatt tgtgaacttg tagttggtgc tttctcatgt
     8401 ttctattctt ctcctttttc taaagactgt aaatcgctct tccatgtctg gtgttggtaa
     8461 gccatctccc aaaacttggc ttccatatga acactgatgt ggaaggcatc tagcattttt
     8521 tgcttatctg tctcatcact ttctcgatag agctgattga ccagtgctcc ctcctctctg
     8581 atctgttgct ctaactcatc cgtaatataa gtttcaatcc attgttgata gagaggattt
     8641 ggtgatggtt taagattaag tgatttgcct atatcatggt ataaccaagg acaaggaagc
     8701 aagcttgcaa aagctatggc taagttcggt tctgcaaatt gcctataaat atgagaaatg
     8761 taatgataac aggttggagc aattggatgt tgctccattt cctggtcgct gatttccatt
     8821 tccttgaaaa attgttggcg aataaataac tcaccctcca ctaaaccctg agcattttgt
     8881 ttcaagagtc ttttcatctc ttggtttgaa gtcttatcag ccaaaagatg atagatttct
     8941 gagaaggcct tcagatagta ggcatcctga atcaggtaat agcggaaaat ggcaggttct
     9001 aaattcccct cttgtaattg taaaataaag ggatgatgaa aggaagcctg ccaagctttc
     9061 ttggataatt ccatcgcaat atctgtaaat tccataataa ctcctttata aaaatagact
     9121 ggtttgaagc aataaaaaga aaagcaggta gattaatttt gtttttttag gaatataaaa
     9181 agtccgatag ctattcttca actgtgcatg ttcgtcatat ccatgagcag acagagctct
     9241 caggtaaaga tggcgccacc taaagactgt catcagaacc ttactgtaaa tcaagggcga
     9301 ccaaaaatgc agttcttgac cacgtaatag gcaagcttct ttgagggact tgatttcttg
     9361 ctgaatgaga ggaaaggaat tgaataccac aatcaaggca taggaccaag agcgtgatag
     9421 ccccttttga gccaagtaca agagaagctc ttttagtgaa atagaggaaa caaagacaag
     9481 gccgatacaa actgtcacaa aggccctcgt tccaagcatg actgcctgtg aagcatctcc
     9541 gtgtaactga actgcccagt agttggcaaa agatggtaaa atggcaagta tgatcatcca
     9601 agctaacatt ttaaatcgac ggtaatagag cataaagaga atacaaaatg cgactaccga
     9661 aagattcaga gcaatcgaag gaatgaaaga tgtttccaag gataaaatca gcaagaagag
     9721 actgataatc ggtgtctggg ttgctacttt gaccatacta tctcacctcc ccttgggtat
     9781 tgctactctg agatgtaagt ggtttggtaa tggtcacttc tttcacatgc cgaagaccct
     9841 gactagtcat ctcaatccaa taatcaacca cagaaatcaa agggtctaaa cgatgactaa
     9901 tgagcagaaa acttcttcct tgattcctct cctccacaat ccacttgcaa aaataatggc
     9961 aggctctatc atccaaacct gcaaaaggtt catctagcaa gatcacggaa gccttactgg
    10021 tcaagatggt caagagctga agaatttttt gctgaccacc acttaattga tagggactct
    10081 tatcgactgc ctgctccaaa tcaaaatatc gtaaagcttg aaaaatccgc tgatttcttt
    10141 cagaatcagg tccatctaat tgaagctcct ctcgcagact gactcggata aactgcttct
    10201 cagcttcctg aacaacacca gtcagatcac gatacaaact ctttttcttt ttcaggactg
    10261 tccccttcca tgcaatgcgc cccttatact tttgaaattg aagaatagag cgaaagaggg
    10321 ttgatttccc gacaccattg tcacccagga tacaggaaat cccttgatag aatgtgaaat
    10381 cagcaattga aaagaggggg cgattaccaa gctcaccagt cacacggttc atatggaata
    10441 gttccgggct agaagcaact tcctttgaag caacctgtgt catctcatag gaagggattt
    10501 gaaacacttc ccttagtttt ccgtctctta gctcaaccat atggtcgata taggctttat
    10561 agtcagataa atcatggtcg cacaaaataa ctgtcttccc atcaagagcc aactctttta
    10621 gaatctccaa tatctcgatt ctgctcttgc ggtcaataga agcgaagggc tcatccaaga
    10681 gatagaccct aggattcatg gcaaagagga cagccagcgc tgctttttgc ttttccccac
    10741 ctgataggtg atgaatggga cggtgtaaga ttgcctcgca acgacattgc tggacaacct
    10801 ctgctatttt agaatcaatt tcctgaaggt gatagccgat attctccaag gtgaaaatca
    10861 gctcctcaaa caagttctcc atggtaaatt gatgattggg attttgaaag agaatgccaa
    10921 ccttctggac acgtgcgatg atagaaagct gactgacctc gctcccatct atcaggactt
    10981 gaccactata gggaagagaa ctgacttggg caatgacttg aaaaaggctg gattttcctg
    11041 aaccactgct cccaactaac aaggtaaagg cttgcgcatg aaaagtaaaa tcaaacggct
    11101 cagagaagat tggggactga atcgctcgta gttccagacc catctatgct tttcctccag
    11161 ttgcaaactg atgatagagt ttgacaatgg cacgaaccaa gatggtacag aagaaataaa
    11221 cagaaataaa acgtaccaca agtaaggaaa ggacaaacgg aagggaaaag gcgtagtaac
    11281 ctaacttaat gtattcatag acaaagctaa caagcgtaat cccaatacta ttagcagtta
    11341 gagagagcca actttcatag cgattcttag ttacgataaa accaaattca cttcccaaac
    11401 cttgaaccaa gccagacaaa agagctccta gaccaaattg gctaccataa aggacttcag
    11461 caagcgcagc tagcacttct ccaatcgttg cacttccgac tctcggaaca aagatggcag
    11521 caatgggcgc agccatacac cagagaccga agaggatttc attggcaaag gcctgcaaac
    11581 caagaggtgt taagagtaga ctgagaatat tatacacata tcctgaacca acgaaaaccc
    11641 caccaaaaaa gatagacaag aaagcaagca agataacatc ttttaactgc cattttttca
    11701 acataaaaaa ctcctttttt aaaagaaaag tggggcactc aagaagaccg acctaaatac
    11761 tttgtatagc agattgaatt tagaacagta cacaggaatg ctaaaatatt tctagaaatt
    11821 aatttgaatt ttctaattga tttgttcgca tcttatttca atctactata tcatcttcat
    11881 ccagtttcgt aaaagaaaaa actctaatta cagatacgaa ttagagttca gcttacaaga
    11941 ttagacagtt cttttcgaca tacgaaaaaa acatttcaca tttcccttcg ccagtcttaa
    12001 ctgtatcagg ttcaatgggt atcatctcag cctaaagcac cccaaatgcc tttattattt
    12061 aattatgtga ttattataac acacatttta tactagttca agaaattgaa ctggaaatac
    12121 agccttgcac tcacaaagac agcagatctt tcttttgcaa aaaacaaatg acctgtttga
    12181 tgaattagcc attcaagctg aatctagaca tagcttttta aaaaaggaaa atcctactta
    12241 cttagaatcc aaggatagat atctattgtt cactcatttc ccgaacagtt ttttctatat
    12301 tttttgcata cgatattgcc gaaatgattg aaacgccgtc aacattggtc tttataatgt
    12361 ctttaatatg tttcgtctgt atcccaccaa ttgcaactaa aggcatttgt ggcaatagtt
    12421 ttctcatcaa ttcaagacct tcataaccta tagcaccacc agcatcatct tttgactggg
    12481 tatcaaatac aggcccaaca cctacataat ctacatattc aacttttgat tgttgaaatt
    12541 cttcttcgtt tcttatagaa agaccaatta ttttatctgg catcaatttt ctaatttcat
    12601 caacaccaat atcatcttga cctacatgta cgccatcggc gtcaatttcc attgctaaat
    12661 ctatatcgtc attaacgata aatggaacat tgtatttttt acaaagttct ttaatttgga
    12721 tagctagctc aagtttttct aagccttcta aagcaccctc acctttttct cgaaattgaa
    12781 ataaggttat agcacctttt aaggcttcct caacgactgt atatagattt tttccttggc
    12841 aagtagtcgt tccacaaata aaatatagtt ttagtaattc tttatgaaac atcttacttc
    12901 actcttttga attcctttac atcttcatct gtaatctcgt ataaggcatt tataaattca
    12961 gctttaaatg ttccaggaag atgtccattg ggacgttttt ctgctatttc tccagcgata
    13021 ttgtaaacca acattgctgt ttctaatgat ttcaattctt gacctttttc tagtccgata
    13081 aagcttgcta ctacagctcc taataagcat cctgtcccaa tgactttcgg catcatagca
    13141 ctaccattat gaatcgttac cacttctcca ttaacagcaa tggcatccac ttcacctgtt
    13201 actactattg gaatattgaa cttctcattt gctgctagag caatttcgtc aatattatct
    13261 acgcccgcac tatctactcc tttagatgcc acatctattc ctactaaaga ggcaatctcg
    13321 ccagcatttc ctctaatcgc tgctagttta taattgttga ttagatcatc cgctactttt
    13381 tttctatatt ctcctgctcc acaggctaca ggatctaaaa ctgctgggac attatatttc
    13441 tccgcaattt tcagagcagc ttggtataat ttccaatttt catctgtcaa tgttcctatg
    13501 tttattaata aaccaccagc atactttaac aaatcctcta aatctgctgg aaactcactc
    13561 atggctggtg aggcgcccag tgctactaat ccatttgctg tgaaattttt tactacatca
    13621 ttggttatac aaatgaccaa tggtgctttt tcttttaata attttaaact tgtcatattg
    13681 aaatccttcc ttttcacttt atacgatcta ctgatttcga tttatatcta tctttcgtta
    13741 agaaattttt ttcatttaca ttgaatgatt tatactcaat gaaaatcaaa gagcaaacta
    13801 ggaagctaac cgcaggttgc tcaaaacact gctttgaacc tgtagataag actgacgaag
    13861 tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccatacct
    13921 acggcaaggt gaaactgacg ttgtttgaag agattttcga agagtcttac ctcatcaaat
    13981 ttgtaaatat catgagcctt ctctagacat tgtaaccaat atcaaaaaaa gctaattcta
    14041 aagcgactgc ttgattccag cgttgctgaa gttctgtcaa atcttctcga tttttaccga
    14101 cacgattgag ttcgtcaacc agaaattgaa cccactctgc aaagaaagga cctctgtgga
    14161 gattgatcca ttccgaatga atatagactt caggtagagc caaatcttta gaaccccagt
    14221 ctaaatagag accttctgca atgaccagca taaccaaaag atgggcatag tctgatgaag
    14281 ccactgccga atacattaga tcctgaaagg cttttgttac agggtgcaaa gtcacttcta
    14341 gatagtcatt ctctgctact tttaactctt taaaagcctt ttggaaataa ccatcttcat
    14401 ctgcttcaag aaagcctagt tgcttggcaa aacgaagctt ggattcaagt ttatctgcgt
    14461 gagctacgca ggcacccagc atggataaga aggcatcaaa gaagtgataa tcttgaatca
    14521 gatagtcctt taagacctta ttctcaattg tccccgcaaa aagttcctta acaaaacgat
    14581 gattgattgc agcctgccaa tccttctgac tgctttttaa taattctcca acagtcaaac
    14641 ctggctgaaa tgcatagtct tgtgtttcca tatttacttc tcctctcttt acttgttagt
    14701 aattaataaa acaccaagaa atatcaagca aaatcgtaat tccacttgat ccttttaaag
    14761 cacatcgaga gcatttgcag agagctaact aaacaagcct atccagttta tataaacaaa
    14821 aaactccaat tacaatcaag aattagagtt gacttacaag attagaccgt tcatttcacc
    14881 atacgaaaaa actgttcaca tttcccttcg ccagtcttaa ctgtatcagg ttcaatgggt
    14941 attatctcag cctaaagcac cccaaatgtc tctattattt aattactgaa ccagtatagc
    15001 aaaaaatgaa agccctagca agatatttga ccgaaaaata tctttatata taatatattg
    15061 aaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt aactgtcctg
    15121 attaatttgt cctattctta tttcatttta ttatagtttt cgatagcgat ttattcttcc
    15181 aatacacgaa gaaaaacctc cacattcagt ggaggcaatc tgttttatca atacaatttt
    15241 aagtcacgag ggtcaactgg gaaggttggg ttgtatggat tgtgacggag cttaaagtgt
    15301 ttgacatctt caatggtctg agctccagac aattgcataa ctgtcttcaa ttccgcattc
    15361 aagtgttcaa agacttgacg cacaccgaca ctaccaccga gagccaagcc ataaataaca
    15421 gggcgaccaa tagctaccaa gtctgctcct gaagccaagg ctttaaagac gtgttgacca
    15481 cgacgaacac cagagtcaaa gacaatcggc acacgtctat caactgcttc tgccacttct
    15541 tgaagcgagt caaaggcagc tggtccaccg tcgatttgac gaccaccgtg gttggttacc
    15601 cagataccag aagctcctgc agcaagtgaa cgttcaacgt cctcacggca ttgtggtccc
    15661 ttgacataca caggaagacc agagtattca gcgataaatt ctacatcgcg tggagacaag
    15721 cgttgtttag ctgatttgta aacaaagtcc attgatttac cagcaccttc tggcaggtat
    15781 tcttcaacaa tcggcatgcc aactgggaag acaaaaccat tacgcttatc cacttcacga
    15841 ttccccccta cagtagcatc tgccgtcaag acaatcgctt tataaccttc agccttcaca
    15901 cggtccatga tgtggcggtt gataccgtca tccttactaa agtaaaattg aaaccaatga
    15961 ggtgtccctt gaagggcttc agaaatctct ggaaggtcaa cagtagagta agaactggtt
    16021 gtataaagag aaccaaactc atgcacacca cgcgcagtcg ccacttcccc ctgttcattc
    16081 gctaatttat gggccgcaac aggcgccata atgattggtg aagatagttt ttcacctgca
    16141 aattcaatct ctgtacttgg attttcaaca tcgcaaagtg tatgaggaac gatgagtttg
    16201 tggttaaagg cgcggatatt ctctcttaaa gtgaaagtat cttccgcccc actagcgata
    16261 tagccaaatg ctgctttagg aataacttgt tgcgccattg gctccaaatc ataggtattg
    16321 atgaagtcta catgaccttc tgcattgctt gttttgtatg acataaaatg ccctccttga
    16381 ttaagtaagc gtttgctttt tactacacaa ctataataac tcttttttca atcattttca
    16441 agagttttgc ttaaaaacca tcttattttt tcatacaata tactagccct actttcctta
    16501 aactctaaac tttagtctat attaagtgaa tcgttgagat tttttgctgc caggcatttg
    16561 aactactttt ttatttgcgg attctatcta ctaatactat aaaaaaacaa gtgaataaga
    16621 caccagaaca tcctctaata ggacctatgg acttatatca gtcccatata tactgtttaa
    16681 gcaagatact atcctagttg acgctaactt cctatcccac ttattaattt tttatttata
    16741 gtgaatctga acaaatcaat tgggaaatcc aagtcaattt ctagtacttt ttgaacagtt
    16801 tcagcgtact atcgtaaaat gaaataaaac atgcacaaat tgattaggga atttaaacca
    16861 atttctaaca gtgtcttaga aatcaaagtg tactatttca acttcaatat actacacttc
    16921 attttctcct taaattcagt ctctttttga atcaaaaaat cccctggtaa gagccagagg
    16981 gtaagaattt atttcattgt tgggaagagc aatacatcac ggatagttgt tgtatcagtg
    17041 aggagcatgc agagacggtc gataccgatt cccaaaccac ctgttggtgg cataccgtat
    17101 tcaagagcct cgatgtagtc atagtcgatg cctgtcgctt catcatcacc aagttcttta
    17161 gctttagctt gggcttcaaa acggctaagt tgatcgattg ggtcgttcaa ctcagtaaag
    17221 gcattaccgt actccttagt catgataaag agctcgaaac ggtcagtaaa gcgttggtct
    17281 tcaggatttt tcttagcgag tggagataca gctactggat gtccatagac aaaggttggt
    17341 tggattaaag tttcttcgac aaactcttca aagaaggcat tgatgatgtg accaacctca
    17401 gtgtagtgtt tctcaactgg aactttcttc tcagcagcga tagctttagc ttcttccaaa
    17461 gtcatgtctt gccagaaatc gacaccagta atttctctga tagcatccac catatgaaca
    17521 cgcttaaatg gtttgttaat cttgatttca gtaccttggt agttgactgg gccatcacct
    17581 ttgactgatt tagcagcgtg ttggataatg ccttccgtca agtccatgat gtcttggaaa
    17641 tctgcataag cttggtaaac ttcgatagaa gtaaactcag ggttatgagt agcgtccatt
    17701 ccttcgttac ggaagatacg gccaatttca tagacacgtt ccataccacc cacgataagg
    17761 cgttttaagt gaagctcagt cgcgatacga agcaccatgt caatgttttg ggcattgtgg
    17821 tgggtgataa atggacgggc agcagcacca ccggcttcat tatgaagaac aggtgtttcc
    17881 acttcaagga atcctttttg gtcaaggtaa cgacggattt cagagatgat ttttgaacga
    17941 gtgacaaagc gttcaaagct ttcacgatta gaaatcaagt caaggtaacg tttacggtaa
    18001 attgtttcaa cgtctgtcaa accatggaat ttctcaggaa gaggacgaag agccttagac
    18061 aagtgtgtga tgtgggttgc cttgatagag agttctccca tatccgtacg catcacttca
    18121 ccttcgacac caaggaagtc accaaggtct gcttttttga agatttcgta gttttcttca
    18181 ccgacagcat ccttacgaac atagatctga atctggcctt cgcggtcttg aaggtgggca
    18241 aaaccaactt ttcctttacc acgtttggtt accaagcgtc ctgcgatagt agctgtttcg
    18301 tttttatcgt gtaattgttc tttatcgagg ttggcatatt tatcttttaa ttcttgtgaa
    18361 tttgcagtac gttcaaaacg ttttccgaaa ggatcgattc cttgttcgcg gagcgcagcc
    18421 attttttcac ggcgaacgat ctgctggtca tttagttctt ccatatgttc tgtagacatg
    18481 ggatcctcct agttttactc aaaattgaat acgatgagtc attttttgcg atacccccat
    18541 tttatcataa ataagcaaga aattcacgga taatctttaa aaactaaaaa gaacctgacg
    18601 ctaaaatcac tggaaagaag tgaaagtatc ttccgcccca ctagcgatat agccaaatgc
    18661 tgctttagga ataacttgtt gcgccattgg ctccaaatca taggtattga tgaaatctac
    18721 atgaccttct gcattgcttg ttttgtatga cataaaatgc cctccttgat aagtaagcgt
    18781 ttactttgta tattgcagtt tggggaagtt tgggatcctt tctgctcggt ttaatcgtta
    18841 gtatcatccg acattatcga atccctgttt tggcgcaagt agcgacagcc tacattgaat
    18901 tgtcacgtaa tacgcccctt ttgattcaac tcttctttct ctacttcggt cttccccgaa
    18961 tcgggattgt cctatcttca gaagtctgtg caacgcttgg gcttgtcttt ttaggaggct
    19021 ccgccatgca ggattcggga atccaagtac tctttcaagg aaataacctc ctgagaatct
    19081 tacagggatt gggcgttacg attgggatat ccatcctgtc tgtcctctta tccatgatgt
    19141 tcggaacagt catgggaatc atcatgacct cccattctag aatcatacga tttttaacac
    19201 gattgtatct ggaatttatc cgtatcatgc cccagctggt gctactcttc atcgtttact
    19261 ttggcttggc tcgaaacttt aatatcaata tctcaggtga gacttcagtt attatcgttt
    19321 ttaccctctg gggaacagct gaaatgggag acttggtacg tggagctatc acttctctcc
    19381 ctaaacatca gtttgaaagt ggacaggcac tcggcttgac taatgttcaa ctttactacc
    19441 acatcatcat cccacaagtc ttgagaagac tgctaccgca ggctatcaat cttgtcactc
    19501 ggatgattaa aaccacttca ttagttgttt tgattggggt tgtggaagtg accaaagttg
    19561 gacaacaaat catcgatagc aatcgcctga ccatcccaac tacttcattt tggatttatg
    19621 gaaccattct aatcttatat ttcgcagttt gctaccctat ttccaaacta tccactcact
    19681 tagaaaaaca ttggagaaac taaatgtctg aaactatctt agaaatcaag gaactaaaaa
    19741 aatccttcgg agacaatccc atcctccaag gactttctct agaaatcaaa aaaggggaag
    19801 ttgttgtcat cctagggcca tctggttgtg ggaaaagtac cctccttcgt tgcctcaacg
    19861 gcttagaaag tattcaaggt ggagatattc ttctggatgg tcagtctatc gttgaaaata
    19921 aaaaagattt tcacctagtt cgccaaaaga ttggcatggt cttttaaagt tatgaactct
    19981 ttccccatct ggatgtctta caaaacctca tcctaggccc tatcaaaact caaggatggg
    20041 acaagaaaga agtaacggaa gaagctttgc aattactaga tcgtgtcggt ttgctggata
    20101 aacaacatag ctttgcccgt caattatctg gtggacagaa gcaacgtgtt gcaattgtcc
    20161 gtgccctcct aatgcatcca gaaatcatcc tttttgacga ggtgactgct tcgctggatc
    20221 cagaaatggt gcgtgaggtg ctggaactta tcaatgattt ggcccaagaa ggccgtacca
    20281 tgattttagt aacccacgaa atgcagtttg cccaagccat tgctgaccgg attatcttcc
    20341 tcgaccaagg gaaaatcgct gaagaaggaa cagctcaagc cttctttacc aatccgcaaa
    20401 ccaaacgagc ccaggaattt ttaaacgtct ttgactttag ccaattcggc tcatatctat
    20461 aaaggagatt cttatgaaac tattcaaacc actcttaact gttttagcac ttgcctttgc
    20521 ccttatcttt atcactgctt gtagctcagg tggaaacgct ggttcatcct ctggaaaaac
    20581 aactgccaaa gctcgcacta tcgatgaaat caaaaaaagc ggtgaactgc gaatcgccgt
    20641 gtttggagat aaaaaaccgt ttggctacgt tgacaatgat ggttcttacc aaggctacga
    20701 tattgaacta gggaaccaac tagctcaaga ccttggtgtc aaggttaaat acatttcagt
    20761 cgatgctgcc aaccgtgcgg aatacttgat ttcaaacaag gtagatatta ctcttgctaa
    20821 ctttacagta actgacgaac gtaagaaaca agttgatttt gcccttccat atatgaaagt
    20881 ttctctgggt gtcgtatcac ctaagactgg tctcattaca gacgtcaaac aacttgaagg
    20941 taaaacctta attgtcacaa aaggaacgac tgctgagact tattttgaaa agaatcatcc
    21001 agaaatcaaa ctccaaaaat acgaccaata cagtgactct taccaagctc ttcttgacgg
    21061 acgtggagat gccttttcaa ctgacaatac ggaagttcta gcttgggcgc ttgaaaataa
    21121 aggatttgaa gtaggaatta cttccctcgg tgatcccgat accattgcgg cagcagttca
    21181 aaaaggcaac caagaattgc tagacttcat caataaagat attgaaaaat taggcaagga
    21241 aaacttcttc cacaaggcct atgaaaaaac acttcaccca acctacggtg acgctgctaa
    21301 agcagatgac ctggttgttg aaggtggcca ttaactctta aaagggactg gattttaagc
    21361 tccaatccct ttttaagatt ttacctataa catcctgagt ctatctaaga tgttcaatct
    21421 gaacacagtg tacatacttt atcttctatt gcatatactt tatcacataa gatacgaata
    21481 tcctcttcac tatgactagc aatcaaaatt gttgtccctt tttcactaga gagctttcta
    21541 aacaatgttc tcatattttc tacacttgat ttatccaagg cattcatagg ttcatctagt
    21601 aaaagaatag agggattctc cataattgct tgagcaatcc ctagcttttt cctcatacct
    21661 agcgaataag ttttaacttt ctggtctttt tgctcatata gaccaactat tttcagtgta
    21721 tcattgattt cctgattacc aactactcct cgtatgcttg ccaaatattg taaattctta
    21781 aagccactat aataatttat aaaaccaggt tcttcaatca aagctcccaa attagctgga
    21841 atttttctct caggaacaat attttcccca ttgattaaca cttctccata agacggacta
    21901 tataaaccag ctattaattt aaacaataca cttttccctg agccattcgc accagtgatt
    21961 cctatgattt cccctggttt acaactaaag ttaaggtttt gaaaaacaca tgtctttttt
    22021 aatttcaact caatattttt taatatgatt atttcattca ttctataaac ctcctctttt
    22081 gacgagtgaa atagaaaata cttttaaaaa gaaagactaa aaatagcaac tgaagaaata
    22141 aatctcgtcc tatatctcca ttccctcgat tcaaaatata aaatagataa ttagttcgat
    22201 tccctacaaa tagaccacca aacacaatca tgagtaaaaa gaaactaacg caagcaaagt
    22261 tcatttgtac attcgctcct agtgcgtata acataaagca aagcaaggat agcacacaag
    22321 cattcaaaga atcaactata aacaaaactc ctatatccca gtttggtaac tgtaacataa
    22381 attgaatcac tagaactttt accatgatta aaatgagtcc ataaagaaaa caggtccaaa
    22441 tctgatacct aatccagagc ttaatagaag aaaatcgaat cacttccata aagaaatcgg
    22501 atgctcttct acgatataca actgctagaa aaaatgtatg aataataaac caatgaagca
    22561 accatatgga taagactaaa aaagagtttt gactcagatt aggccctttt aaaatttcta
    22621 taacaagtct atcatttcct tctaaccaat accataatcc taaacaaatc aatatccaaa
    22681 aaagaacata accccaaaag tacttggtat agattatctg attcaacctc cacatgtaac
    22741 tacttaactt tcccatttcc aacttttaca ctctcctcca gtttctatga acagaaaata
    22801 cagtcaatgg aattatgata gatagtaatg taagccaata aatcaatgca tacggattgg
    22861 aatttaccat atactgaaaa attggcaata atccaattat cccattgtcc aactgataaa
    22921 tccagaataa ggattctaca aataaaaaag taaacagaaa tactaagctc atgtttgatt
    22981 ttttaaacca agaaaaactg ctaatagtaa gtaaggataa aaagaaatag tatgctatat
    23041 aagagaaaaa aaatcctata aagaaactag cattgtttgc aatacttata ccataaaatt
    23101 ctcttaaaaa atcaacctcc tttatctcca aagagaagct aaaaccatta ctaaatgcaa
    23161 ttagaaaaat caataaaaat aaagtcgccg tccaaatccc cgtactaaga gctgctaatt
    23221 tgaaactaaa actggtaaag tgcttaattg atttcagacg aatgcgacac tccaacctat
    23281 taaaatagtt attcatcaaa taaaaaaaga acaatatata tgtgaacgga aagcaatata
    23341 ctccagtcgt catatcttga agtaaaacta agatccattc taatacattt ggatggattg
    23401 aatattggcg acagcgcaat aaatatactg tactagataa aacacaggat agcagtaata
    23461 taaaataaac caatactgct aagaaatctt ttttataaaa ttgaacaaat tgtttcatta
    23521 tacgtagtcc tctgaatgta gaaaaaatgt accataaaca accaaacaac taacaaataa
    23581 aataaaagca agatgcccac taactaagga aagactgata tctttctgat atcccaaagc
    23641 taatgttgtc acaggttcta agtaagatag ccctaaaata gcccaaaaaa taccaccaac
    23701 catcatatag gcaactggga tgaaaatagc tcctattttt ttcttcacta gcaaagcact
    23761 agctagtcca aaaatagaga acacagcgcc ccaaactcca taccagagag tcgtcacaag
    23821 actatagagc aactgattag aatcaaataa ttcttttaag gcaccactat aatctccaat
    23881 ataaatttcc tgataaggag tcactaaaag attaattcct aataataata aataggggag
    23941 aaaaaagact agaaaagaag aaataattgc agtactaccc acaatagcta gatacctctt
    24001 tttagaaatt cggcacaatt gtgctgttag aaaatgactc tcagcatcct ctattatctg
    24061 actagaatag ggcagtgtac agataagtgc agctactagg ctaatcggtg aaaatcctcg
    24121 aatagaagaa gcggcaaaaa aaatcgataa accttcaatt ttataaatac cattgaaagc
    24181 aaggaaattt cctaaactca tgcaaagaag ggtcaaaaat aaagacatat aaaatcgagg
    24241 tgattgaacg actcgtacaa gattacaaat gaaaaattcc atcct
//
LOCUS       DAVLHM010000032        24078 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLHM010000032 DAVLHM010000000
VERSION     DAVLHM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24078
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.032"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(293..1900)
                     /locus_tag="VXE45_001447"
     CDS             complement(293..1900)
                     /locus_tag="VXE45_001447"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0789465.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENRN"
     gene            complement(2290..2877)
                     /locus_tag="VXE45_001448"
     CDS             complement(2290..2877)
                     /locus_tag="VXE45_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0789466.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3005..3454)
                     /locus_tag="VXE45_001449"
     CDS             complement(3005..3454)
                     /locus_tag="VXE45_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789467.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3459..3848)
                     /locus_tag="VXE45_001450"
     CDS             complement(3459..3848)
                     /locus_tag="VXE45_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0789468.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3876..4502)
                     /locus_tag="VXE45_001451"
     CDS             complement(3876..4502)
                     /locus_tag="VXE45_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0789469.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4516..5079)
                     /locus_tag="VXE45_001452"
     CDS             complement(4516..5079)
                     /locus_tag="VXE45_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0789470.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5244..5393)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5453..5956)
                     /locus_tag="VXE45_001453"
     CDS             complement(5453..5956)
                     /locus_tag="VXE45_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0789471.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6149..6979)
                     /locus_tag="VXE45_001454"
     CDS             complement(6149..6979)
                     /locus_tag="VXE45_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0789472.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRLLV
                     LIAIFSVFLLYLSEIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(6964..8646)
                     /locus_tag="VXE45_001455"
     CDS             complement(6964..8646)
                     /locus_tag="VXE45_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789473.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTDPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
     gene            complement(8748..9005)
                     /locus_tag="VXE45_001456"
     CDS             complement(8748..9005)
                     /locus_tag="VXE45_001456"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789474.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9012..9560)
                     /locus_tag="VXE45_001457"
     CDS             complement(9012..9560)
                     /locus_tag="VXE45_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0789475.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9575..10423)
                     /locus_tag="VXE45_001458"
     CDS             complement(9575..10423)
                     /locus_tag="VXE45_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0789476.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10611..11960
                     /gene="trkA"
                     /locus_tag="VXE45_001459"
     CDS             10611..11960
                     /gene="trkA"
                     /locus_tag="VXE45_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0789477.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11964..13403
                     /locus_tag="VXE45_001460"
     CDS             11964..13403
                     /locus_tag="VXE45_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0789478.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13528..15207)
                     /locus_tag="VXE45_001461"
     CDS             complement(13528..15207)
                     /locus_tag="VXE45_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0789479.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSVMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(15276..16688)
                     /gene="lacG"
                     /locus_tag="VXE45_001462"
     CDS             complement(15276..16688)
                     /gene="lacG"
                     /locus_tag="VXE45_001462"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0789480.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVQYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(16698..17042)
                     /locus_tag="VXE45_001463"
     CDS             complement(16698..17042)
                     /locus_tag="VXE45_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0789481.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(17210..19096)
                     /locus_tag="VXE45_001464"
     CDS             complement(17210..19096)
                     /locus_tag="VXE45_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0789482.1"
                     /translation="MVIRVFDQQKNTYSSFALEELRYYMNQVFNTDIELVEEKEADIF
                     VGLVNEEDGKDHIFISLNKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFIP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYKDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(19098..20420)
                     /locus_tag="VXE45_001465"
     CDS             complement(19098..20420)
                     /locus_tag="VXE45_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0789483.1"
                     /translation="MNNILTFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRIFIQRGITIKMPNGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            20588..21811
                     /locus_tag="VXE45_001466"
     CDS             20588..21811
                     /locus_tag="VXE45_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0789484.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPSVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTATKYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKKFDFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            22822..23106
                     /locus_tag="VXE45_001467"
     CDS             22822..23106
                     /locus_tag="VXE45_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789485.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDIEKL
                     LDSKELTHFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23099..23656
                     /locus_tag="VXE45_001468"
     CDS             23099..23656
                     /locus_tag="VXE45_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEV0789486.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT         7640 a         5183 c         4066 g         7189 t
ORIGIN      
        1 tctataaatt aatttgactt ttctgataga gatgttcaca tcttatttca attcatgata
       61 caatccagtt cctaaaactt tgctagaaat taatttggct ttccgaatta atttgttcag
      121 attttatttc atttcaatat actgataaat ccattcacta gcacagggca agagggagtc
      181 gctattgatt tcaacggtag caggtacata cagaggactc ctacctcaga tatactgcaa
      241 tatcatcgtg tgcaaaaaac ctctgagatt tttctcaaag gttctgattt tgctaatttc
      301 tgttctcaac cgctgcagta acaaaggcag tgtagagttc ttctggtcgg tttggacggc
      361 ttgacagttc agggtgatac tgacaagcta caaagaattt attttcagga atttccacga
      421 tttctaccaa acgattgtct ggagaaactc ctgaaaagac aaagcctgct gcctcaaact
      481 gctcacggaa ggcgttatta aactcataac ggtgacggtg acggcgttgc accacttctt
      541 gattgtgata agcagcagca gccttagagc cacgtttcaa cttagacgga taaagtccca
      601 aacgaagggt tccacccata tcctcaatat caatctgatc acgcatgata tcaatgatag
      661 ggtattttgt ttctggtgca agctctgcag aattggcacc ttcaagacct aaaacgtgac
      721 gagcaaactc gatacatgtc aactgcattc ccaagcagac tcccaacatt ggaacatcat
      781 tttcacgcgc atagcggatg gcttggattt tcccttctgt accacgttga ccaaaaccac
      841 ctggtacgat gatcccgtct gcatcagaca agagttctgc tacattctct gctgtcacat
      901 cattggcatt gacccaattg attttaactt ctgcatcatt gacatagcca gagtgtttca
      961 aggcttcgac cactgagata taggcatctt gcaactccac atacttacca acaagggaaa
     1021 tcttaacttg tttcttgagg ttcatgacct tgtccaccat ggctgaccat tctgtcatat
     1081 ccgctgctgg tgcgtctaat ttcaaatgat cacaaacaat ttggtccatc ccttgtgcct
     1141 gcaagttcag tggaatttgg taaagatgtt caacatccaa cgattcgata acggcttctg
     1201 gtgccacatc acagaactgg gccagtttat ttttaattcc ttgaccagct ggctcttctg
     1261 tacgaataac caacatattt ggttggattc ccaagccacg caattctttg acagagtgtt
     1321 gggttggttt ggttttcatt tcaccagcag ccttgaggta aggaagcaag gttgtatgga
     1381 tatacatgac attatccgca cccacatctg ccttcatctg acgaagagcc tctaggaatg
     1441 gcaaggactc gatatctcct actgttccac caacctctgt gataatgaca tcagagtcgg
     1501 tcgttagagc ggcacgcttg attttttctt tcaaagcatc tgtgatatga ggaatgactt
     1561 gaacagttgc cccaaggtat tctccacggc gttctttacg aagaacttca ctgtaaattt
     1621 tcccagttgt cacgttggaa tatttgttga gattgatatc gataaaacgt tcatagtgac
     1681 ccaagtccaa atctgtctca gctccgtcat ctgtcacaaa aacttccccg tgctggtaag
     1741 gactcatggt tcccggatca atattgatat aagggtcaaa cttttgaatg gttactttga
     1801 gaccacgatt tttcaagaga cggcctagac tcgctgccac aatccctttc ccaatggacg
     1861 ataccacacc accagttaca aaaatatatt tcgtagacat agattcctct ttctaaaatg
     1921 ctcaaggtct tgttaactac gaggggatat agaaaacaag accctactaa taagaataat
     1981 ctgggacgac tgcaccagat tcacaactaa tactcttcga aaatctcttc aaaccgcgtc
     2041 aacgtcgcct tgccgtagat atgtgttcct gactttgtca gtcttatcta caacctcaaa
     2101 acagtgtttt gagcagccta cggctagttt cctagcttgc tctttgattt tcattgagta
     2161 taaaatacaa gaagataact tcttgaaaaa acaaaaatag ctccctaaga actagggagc
     2221 cccgacctct aaaagaggtg cccaaacaat atgataccta aaaataggat aattgtcaat
     2281 agctaactct tattcctcgc tggtttcagc gtcgtcatct gaaaactcgt cgtcgtcttc
     2341 gttgagatcc acatcttctc ccaagtcatc tggagcgatt tcgttgattt ctgcatcata
     2401 agcttccact tcattttttt catcatctgg attttcatca tcgtatgaaa gagctggatc
     2461 tgcttcgtat gcatcttcgt cttctggatc atctgcattg tagtcaatgg catctgaatc
     2521 accatccata aaggcattga cacgtttttt cttagctttt ggtgctactt catcgtcgtc
     2581 attttcttca agagcgatga tttcttcgtc gatttcgtcc acaccatacc atgaacgaag
     2641 accccatttg ttgtccccaa gtgagatgaa gctaccgtca aagttcaact ctgtgtagaa
     2701 caaaggcaaa gcttcgcgga tatcgctgtt tgatgttcca aggtagtttt gaatttcgtt
     2761 tacaagatcg ctaaaatgca tctcatgatc gcgaccacga agttccaaga tagcacgcgc
     2821 tacctcaatc atagatagtt cacttttttc ttgcccagca aatacttcta attccaaagc
     2881 gtttctcctc atttatacta ctatcgccag agcgaacaga ctctgacctc attttatcat
     2941 ttactcttta ttttacgata attttgcgga atagtcaaag gttaaggggg agaaagtggc
     3001 aggattagac taattccaat ataaaactcc ttcctttttc tgttgctcca ttttccacaa
     3061 atccaagcga cttgaaacac ctcctagaag catgattgta ggtgtagatt tccttgactc
     3121 tcaattcttt ccatcctttt actcgagcca attcaatcaa agcacttaga atcttttttc
     3181 caagtcctcg atgttggtaa gcggaattcc caatcacaat ggggagatta tcctgagata
     3241 gtgtaatatc cccaattgga aaccattctc ccttctcctt gacttcaatc caaaaaagct
     3301 caccatgccg atccaaatag gaatacatgg cttccaaggt cgcttgactg taaggaagct
     3361 tcaccccatc tacgaggtaa accaagttca catcctgata ccaagcaaaa gcttcctcac
     3421 aatgattgac cttataataa ggaacaaaac acaatgcact accttttcaa caaaagagtt
     3481 gctgcttgat taaaaccatc acaccagtta taccattttg cttcataccc atcttgagct
     3541 aggatacgat cttctaaatc aaaaacagag taaatctttc tttcctcgca agcttgcgca
     3601 tagagatgat atagttcatc accaccatct ctatcccact cagcagaaat cgtatcccga
     3661 cctgccaata aagcctgata agccctgtga tgcccatctg taatcagcaa acaatctcca
     3721 aaggcaagaa tactgattgg atcgacttgg tttgtttctg ccgactggta aagcatctga
     3781 atatcttgca acttcttttc tgataaatat agttgagtcg gatgaagatc tgctatattg
     3841 actttcattt ctttctcctc aagggaattc gatactcact tctgtttgcc tttaaatcgc
     3901 cattggaagc ggagcttgtc atagaaggga aactcgataa acaggactcc caagcccaca
     3961 cagagactgg caaagacgtc tgatgggtaa tgaaccccca gatagactct tgataccagc
     4021 acactgacta ggtagaggcc aaggacgatt tgtacgattt ttctccagac tggattttta
     4081 attcgttgac tgagaatgac aatcagagta cctaccatca aagttacagc cagagaatgt
     4141 ccacttggga aggaaaatcc cttctcttcc accagatgta agatagctgg tcgtgggcgc
     4201 tggtagatat ttttaaaggt cacgattaaa agacctgcca aagccagatt tcccagcatg
     4261 aagaaacttt ctatcttcca tcgcttacga taaaagacaa aagctgtaat gacaacccaa
     4321 gtgataatca ctgggatatc aatcagacgt gtgagggctc gaaaaagaat agtcaaataa
     4381 tctggtaagt ctcctcgaat ggcagtctga atcgattggt caaaattgac caacatttca
     4441 gggtaaaatt tgaccatata gccaagaata acgaaaagta aaagggcaaa actgcccttc
     4501 attaaaaatg tttgtttatc tttcatagtg ttttaaggtt ggtttcaaaa ggacgtacaa
     4561 caaccagaat gaaacggaaa agattacacc ctcaatcaag ttaaaaggta ataccatggt
     4621 cattaggtag ttggaaagtc ccaaaatttt tccaatatca aagttagcaa acttagcgta
     4681 caaaggaaca gcataaacat agttgagaac caacatggcc aaggttaaac caacagttcc
     4741 agctagagag cctagtagga aacgaagggt tgtccgttcc tttttccaaa tcaaagcaaa
     4801 tacgatgaca aaaactccca aagctacgat attcatcggc aaaccaatgt aagtattcac
     4861 tccttggctg ttaagaagca atttcaatag tgagcgaagc aagagcactc ctagagcagc
     4921 aggcaaatcc atgaccacca gacccacaag gactggcaag atactaaatt cgatcttgag
     4981 gaaagatgcc gctggtaaaa gcggaaagtc aaagtacatc agcacaaatg agatggctga
     5041 taaaattgca atggtcgaaa gtcgacgtgt gtttgtcata acaggttcct ccaattttct
     5101 ataaaatcag aagaagttgg aaaggattcc tctatctatt ctcacttttt atatcccaaa
     5161 aattccctct tactctatta aagaaaaaca aagcaagtgg ttacaatccg gctataaatc
     5221 tatcaaaaca gacaaagcta ttctttcgtc ttctcccatc cagactatac tgtcggttgt
     5281 ggaatctcac cacatcagct tgcgctcgcg gacttcttta aagagaagga aaagatcatt
     5341 tcctagttaa agtcaccgcc ggtcgggaat cacaccctgc cctgaagact cttttatcat
     5401 aacaaaaaac gcttgcaagc gcaagcattt tgttcatttt cattttcatt ttttatttca
     5461 atttatccac ttcataggta tggacgagct caagacctgc aaagttctgc tggcgaagag
     5521 cctcatagac aatcatgcag acggtattag acacattgag actgcggaca tgttcatcat
     5581 tcatgggaat acggagagcc ttctcaggat gttctcgcat aaaatcttca ggtaagccct
     5641 tgtcttcacg tccaaagaga aaataatggt cctcgtcagt cgataaatcc acctcagaat
     5701 agactttttc tgcgaatttc gaaatcagat agagttttcc cttcatctga gatatgaaat
     5761 cttccaaact ctcgtaaaaa taaatctcta gcttatccca gtaatccaat ccagcccgct
     5821 tcatcttgcg gtcatcaata ggaaagccca taggcttgat gatgtggagg ggagaattgg
     5881 tcgcagcgca agtacgcgcg atattgcctg tattttgtgg aatttgaggt tcaaataata
     5941 caatgtgatt tgtcatgact tgcttccttt caccattgca aaaaaatagc cacactgccc
     6001 ggagtcaagc tcagcaaaca gcgtggttaa ggcatcgtta acttacctca caacaggttt
     6061 gaagtaaatc agcgaaacta ctttcttagt ataacacttt cagaatcatt gtcaatagaa
     6121 atgacttgat tttttcaatt ttttcaagct atttccaagg gttgtaaaat cgtccctgat
     6181 tctgcaagat aagtagtaaa ctaactacta aaaacaaggt tgccaagagc aaggtaatat
     6241 agtctccttt tttcaaggcc tgataactat accatgtgcg ttttttctct ttcccaaagc
     6301 ggcgaagctc catggcagtc gcaatggtat caatgcgttc tagcgagcta aaaatcaagg
     6361 gagtaataat gagcagattg cctttgattc gttgcataag agaagctttc ttggataatt
     6421 ccatcccacg cgcttcctga gacatcttga tggtaaagaa ttcttcctgc aaatctggaa
     6481 tatagcgcaa ggttagactg acagaatagg caatcttgta aggcacacca atttgattta
     6541 aactggaagc aaactgacta gggtgggttg tcatcaaaaa gataatagcc agaggaatag
     6601 tgcaaaggta cttaatagcc aaatttagca gataaaagag ctcttgactg gtcagagtgt
     6661 aggcaccgat tccctgccaa atcacacttc tctctccgta aagtccaacc ccatactcgg
     6721 gagaaaagag atagaccatc aaaacgttta aaacggcaaa taccgtcgca aaaacggcta
     6781 caaaggaaac atctttaaaa tggatttctg acaaatagag gagaaagacc gaaaagatgg
     6841 caatcagaac aagcagtctg gtatcatagc taatcatggc cgccaatgac acgagaatga
     6901 aaaagaggag tttcccagcg cctgacaagc gatgaatcac agtatctcta tgctggtaac
     6961 cgattaattt agcttgcatc cttctctcct ttctttgtaa aatgccgtta aagcaagtgg
     7021 atccacgtcg agtttcttag ccaagttgaa gatagaagtc tcttttaggt tggcttttac
     7081 taacagctca ggattgctca acagactagc tggatcagta tcagcaatca attccccatc
     7141 caccatgaca agggctcgat ctgaataatc cagcatcaat tgcatatcat gggtaatcat
     7201 gacaatggta tgcccttgtt gatgcagttc ttcgagaaat tccataatct cagtatagtt
     7261 cttctggtct tgacccgcag tcggttcatc taggaggata atttcagcgc ctaagaccaa
     7321 aattgaggca atagtcacac gttttttctg accaaatgac agggcagaaa tgggccaatt
     7381 acggaattca tagagaccac agattttcaa ggtttcatag actctcgttt caatttcctg
     7441 ctcgtccaca cctcgcaaac ggagtcccag agccacctca tcaaaaatca tattggttga
     7501 aatcatttga ttgggatttt gcagcacata gcctactcgt tccgcccgct ctgcaacaga
     7561 atctcctttt atatcctgtc cttcccaaag atagcggcct tcagtctgga taaagctact
     7621 caaggccttg gctagagttg acttccctgc tccatttttt ccgacaatgg caatcttttc
     7681 acccttttta atatctaaat gaagagattt taaaatcggt ctatcatcat aagaaaacga
     7741 cacgtcctct agtctaaaga gtgactgcaa ttctggggtt tcttttacca gttccgtccg
     7801 caactgaacc tgaccttttg agatagacaa gttatccaga tctgctaatt gttcttcctt
     7861 gactaaatcc acacccaatt gacggagagt ggtgagataa aggggttcgc gaattccatt
     7921 ttgggtcaac aaatcagtcg ccagtaactg gtcagggctc ccattaaaaa ggatacgacc
     7981 atcgtttatc aagacaatcc gatccacagg gcaatgcaga acatcctcca aacggtgctc
     8041 gataataagg gtcgtcgtcc cctcctcctt atgaatctgg tcaatcaatt cgataatatc
     8101 ctgacctgac ttgggatcaa gattggcgag tggctcatca aacaagagaa tcggactttc
     8161 atcaatcaag acaccagcca gactgactcg ctgcttttgt ccacctgaca aatcctgagg
     8221 gcgctgatcc agtaaaggaa gaaggtccag cttttcagcc catttataaa cacgaccttt
     8281 catctcatct agggctgtca catcattttc cagagcaaac gccaaatctt ctgccacaga
     8341 caagccaata aactgcccat ctgtatcctg caaaactgtg ctaaccagat gagacttatc
     8401 atagatgctc atatcaaagg ctgtttgacc ctttatcaaa aattctccat atgtctgacc
     8461 cttgtaaata ttgggaataa tcccattcaa acactgaccc aaggtagatt tacctgatcc
     8521 agatggtcca acaattaaga ctttctctcc cttgtaaatg gtcaagtcta tcccttgcaa
     8581 ggtcggttct tgttgtgttt cataccggaa agagaaatcc ttccactcaa ttatagcttc
     8641 tttcatctta ctctcttcat tcgcttctta gacttctatt ttatcataaa tcaagccctt
     8701 cttgcagtct cttctcttaa aatcttagcg ccaaaaagat tcctatccta gcttacttgc
     8761 ctaactaatc tataaacatc gaaaaagact agttgcccag ccttccccat cattttatac
     8821 tcttcgaaaa tctcttcaaa ccacgtcagc ttcgccttgc cgtaggtatg gttactgact
     8881 tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc agttctatcc
     8941 acaatttcaa aacactgttt tgagcaacct gcggctaact tcctagtttg ctctttgatt
     9001 ttcattgagt attagtcctt tttcaaactt cctgcacgag tttgggttcc tgcataggca
     9061 agtaagagaa gagttcctgc aatagctaca gatacaccat tggcaattcc cgcaacaatc
     9121 ccttgtgcaa atactttttc tgccgcttct tgataaatca caacatctcc aagtggtgcc
     9181 aagacacccc aaacaagggc atttgcaagt agttgaatga ggttaaaaat aagaatatct
     9241 ttccagtcaa aaacaccatt gatcacgcga acgtactttc taaaaagtcc cacaactaaa
     9301 ccaaagagtc cgctagcgat aatccaagtc caccatagac cataaccagc aagagagtcc
     9361 ttgattgcat gaccaatcaa cccgacaagc aaaccgataa tcggtccaaa aataatagaa
     9421 agtagcgctt gtaccgcata ctgaagctgg atgcttgtat ttggaacagg ggttggaatg
     9481 ttgatcatcc cgatgacgac aaagagggca gcgccaattc cgacagcaac aacttgttta
     9541 attgtaaatt taatttccat actattctcc tattttatcc ttctattttc tttatttcaa
     9601 tggtccaaga tgaaccgaca cctacattat aggccttggc aaaggaacct tggttgatag
     9661 ccaaacctaa acgatagaga gagttgatgt aaaggatggg ttgcccaatt ctcacatctg
     9721 caaatgattt gccatagaca acctgatttt gatagaccag catatcagca tgatagatgg
     9781 tcacttcaaa acgatcacca aattctggtt ccagcttgta aaattcttcc cgtgtgatag
     9841 aggtccaaag cgaaccgaaa cgcacatcca gaatatcaat ggctcccttc accagatgat
     9901 cttctatgat ggtcgctacg actggaagct ctacaatctg ttccacactg agctctggcc
     9961 ctacttcctc aaaagtaatg tgaccactgg ccagtttagc accagtatag gcatagacat
    10021 cacgaccgtg gaaggtataa gaatgctctg tgttttgacg cctattggcc acctcagaaa
    10081 tctcacgaat ggctacaatg ccaacgtgtt tcttgataaa ggaaagcgtc ccattatctg
    10141 gcgtgacaat gtattgattt tttgcagtct tggcaactac actcttacgt ttcgaaccga
    10201 cacctggatc gacaaccgat acaaacgtcg ttccctcagg ccagtaatcc accgtctgaa
    10261 agagacgata gctcccctca aaaatattat aaggcgtgat atcgtgcgtc aagtgatgga
    10321 tttttaaggt tggagactct tctaaagcca ctccaatcat agccgatacc gcaccatcaa
    10381 ccagaccaaa gtctgattgt aataccagta aattattatt cattttatct ccttgtatat
    10441 cctttatcat accatatttc agagaaagtc gctaatagct atttcaattg gttagggtat
    10501 agttttacct tatagcgaat tttcactaaa agctcttgtt attagctagt aggtgcattt
    10561 tttcttgaaa aagggtatga tagttacatc atgaaaaagt aggttttatt atgaaaatta
    10621 tccttgtcgg agggggaaaa gttggttttg ccctctgtcg ctccttggtt gcagaaaagc
    10681 atgatgtttt gctgattgag caagacgaag ctgttctcaa tcatattgtc agtcgctttg
    10741 atatcattgg tatccttggt aacggggccg attttgccat tcttgagcaa gccagcgtcc
    10801 aagattgtga tatctttatc gccctgactg agcacgatga agtcaacatg attgcagcag
    10861 ttctagccaa gaaaatggga gctaaagaaa ctatcgttcg ggtgcggaac cctgaatatt
    10921 ctaactctta tttcaaggaa aagaatattc tcggtttttc tcttatcgtt aatcctgagc
    10981 tcttggctgc ccgtgctatc gcgaatatca ttgacttccc caacgccctg tctgtcgaac
    11041 gctttgctgg tggacgcgtt agcctcatgg aatttgtcgt caagtccacc agcggtcttt
    11101 gccaaatgcc catttctgat tttcgtaaaa aatttggtaa tgtcattgtc tgtgcgatag
    11161 agagggatca tcaaattatc attccaagcg gtgacatgac tgtacaggat aaagatagaa
    11221 tctttgtcac tggtaaccgt gtcgatatga tactcttcca taattatttt aaatcacgcg
    11281 ccgtgaagag ccttctcatc gttggggcag gtagaattgc ctattatcta cttggtattc
    11341 tcaaagatag tcgtatcgat acaaaagtca ttgaaatcaa tcctgaaatc gccagcttct
    11401 ttagcgagaa attcccaaat ctctacatcg ttcaaggaga tggaaccgca aaagatatcc
    11461 tgctggaaga aagtgctcaa cactatgatg ccgttgcgac tctaacagga gtcgatgagg
    11521 aaaatctgat tacatctatg ttccttgaca gggtaggtgt acagaaaaat attactaagg
    11581 tcaatcgtac cagtctcctc gagattatca atgcgcctga tttttcaagt atcatcacac
    11641 ctaaaagcat cgctgtagat acgattatgc actttattcg tggtcgagtt aatgcccagt
    11701 attcagacct tcaagccatg caccatctag ccaatggcca aattgaaacc ctgcaattcc
    11761 atatcaagga agccaataaa atgactgcca aacctctttc tcaactgaaa ttgaaaaaag
    11821 gggttcttat tgcagccatt attcgaaagg gcaagactat tttcccaact ggggaggata
    11881 tgttggaagt tggagacaag ctcctagtaa caaccttgtt gccaaacatc accaagattt
    11941 atgacttgat tgcgaggtaa gaaatgaata aaagtatgat tcgttacctc ctttcaaagt
    12001 tacttttgat tgaagctgtt ctcctcttgg ttcctgtggc tatcgctgtc tattaccgtg
    12061 aatcgagcca agtctttaca gccctctttt cgaccatagg gattctcgta ttgttaggcg
    12121 gttcagggag tttacagaag ccaaaaaatc aacggattta tgccaaggag ggagtcttga
    12181 tcgttgccct ctgttggatc ctttggtctt tctttggtgg tctccccttt gtcttttctg
    12241 ggcaaatccc cagccttatt gatgcctttt ttgagattag ttccggcttt acgactactg
    12301 gagcaagtat tttgaacgac gtttcagttc tcagtcgttc cctcctcttc tggcgaagtt
    12361 ttacccactt gattggaggg atgggagtgc ttgtttttgc acttgctatt atggacaatg
    12421 ccaaaaatag ccacctagag gtgatgaagg ctgaggttcc aggtcctgtt tttggcaagg
    12481 ttgtatccaa actaaaaaac actgcccaga ttctctatct cctttatcta gctctcttct
    12541 ccctctttgt catcatctat tatctagctg gtatgcctct ctacgatagt tttgtcattg
    12601 ctatggggac agcgggaact ggaggcttta ccgtctataa cgatggaatt gcccactatg
    12661 gtagctcact gattacctat ctggttagta taggagtttt ggtttttggg gtaaatttca
    12721 atctctacta ctaccttatg ctccgtcggg ttaaggcctt ctttggagat gaagagcttc
    12781 gggcttactt ggtcatcgtg ctggtttcta caggcttgat tagcctcaat actctctacc
    12841 tctacccagg attttccaaa agctttgaaa tggccttctt ccaggtttcc aacatcatta
    12901 caacaactgg ttttggatat ggagatatta ccaactggcc cctcttctcc cagtttatcc
    12961 tcctcttcct catgacaatc ggtggttctg ctggatcaac tgcaggtgga ctcaagatta
    13021 ttcgaggcct catcctttca aaaattgcca aaaatcaaat tttgtccatt ctatctcccc
    13081 accgtgtttt gactctccat gtgaataaaa cggtgattga taaggatacc cagcataaaa
    13141 ttctcaagta ctttgtcatc tatgctatga ttttgctatc ccttatcttt attgtcagcc
    13201 tagatagcaa tgattttctg atcgtgacca gcgctgtctt tagctgtttc aataatatcg
    13261 ggcctattct aggaaccact tctagtttct caatctttag tcctatctca aaaattctcc
    13321 tctcctttgc aatgattgca ggccgcttgg agatttaccc aatcctcctt ctctttatga
    13381 agagaacttg gtctaagaga taaaatacaa aatccctctt tttacaattg tgaaagaggg
    13441 atttttatat taaaaagggg gaacgttttt aaatccaagc ctgtctgtaa gcaaagtcct
    13501 tactcaaata aaagatggaa aaacttacta cacagcttgg taatgctcca atacaaattg
    13561 taaggcttta cttggattct ttgttaaatg aatatattcc attcctctgg tagcaactat
    13621 ctgaatacct aatctttctg catccacctt catctctcta taataactcc gaacttgtgg
    13681 agccagaata attaaatcat aaacacccat aatatcataa tgagctccgt acgctcctga
    13741 attcgcaatc actctaactt ctgctaattg agcgccctcg ttaattgcat tggctaattg
    13801 cgcacttgtt ccagaccctg cacaaagaac cagtactttc aactccttac tttttatttc
    13861 atctaactca ccaggcatta tttcacttgt ctcctcctct aaaataatat catttgagct
    13921 tgcaacatct tctttcatca gtaactgtct atcatacgct ctacagaatg gcaaataaat
    13981 caatatgtcg acaactaaaa tcaaagataa aaatacaaag gagatagatt gaaaattcgt
    14041 tccaattaac aatcccaagg gaccaggaaa ggcccaaggt aactggatat aaaatccatt
    14101 cattccaaag aaatcaataa agacctttcc tagaaataca ttcactggtg gagtcatcaa
    14161 aaaaggtaca aaaagatagg gattcaaaat aactggcata ccaaatagaa gaggttcatt
    14221 caccgcaaat aaaacaggag taattgtagc tttacctacc gattttaatt gtttagaccg
    14281 cataaagaaa atcaaaataa atggtacaac aaaggtagcc cccgttcctc cgatagcagc
    14341 gatataattt ccgaaattag gcgttaaaga atgataagga aactgcccat ttgcaagaag
    14401 ttgagcattc tcttccatat tgctcagttg taaagctgta acagcaggta agacaataga
    14461 tggtccatga attccaacaa accaaagcaa agcgcacata aaccaaatca acatcatagc
    14521 aggatatgat tctgccccct taaaaatagg agtcaatagt tgttgaaata cttgggcaaa
    14581 aggaacatct aaactaaacc gagatacaat atctaacaaa ccactaataa gtaaaacaaa
    14641 agaaaaagga aaaatatctc taaaagcttg tgatatagcc ccaggaactt ccttaggtaa
    14701 atgaatagta atgtctcgct taatacagaa tcggtaaaca tttacagtaa taaaggcact
    14761 gacaaacgaa gttatcaatc cttgagatcc taaatagttt gtcgacaaac ttgtagatcc
    14821 cgtcttctca tcaactacaa gcgttacagt taataccaga taactacata tggctgccaa
    14881 cattacagaa gtatcattta ttacctttcc aggaggcatt tttctattaa catttccagc
    14941 caatgacttt gcaactgtcc ctgaaacaat aacacccaaa actcccatgg ttagcatata
    15001 cactttcctc atccaggcaa tagctggact cggtaactct actccgaaat ttttaggaat
    15061 cataataata atcatcaaaa agcttgaaaa cataattaaa ggcatagtag caatgaatcc
    15121 atctttaata gccatcatat aattattagt agaaattttt tcaaatttcc cttgttgctt
    15181 ttcaatggca gcgactagct tatccataaa actcctccta taaaaaattc aacctcatat
    15241 ttaaaacata ttaaacatca ttcaaatcgc taaccttaat tccgttttag cccttttacc
    15301 caaagagcac ttttcttaat atatcgcttc tgtgtctcat aatcaacaaa gaaaagacca
    15361 tatcgcttat tgtagccatt cgcccaagaa aattgatctt gcaaagacca tataaaatat
    15421 ccttgaatat tgactcccct atctcgagcc tctaaaactt tgtgtaaatg ttgctcaata
    15481 taacggattc tcttactgtc atcaataata tcattctcgc cctctggctt aacctcttta
    15541 agggctgtac cattttcagt taaataaatg acaggatgtt gaggatattc ttctttgata
    15601 cgaagtaaca tatcaaataa gccttgagga taaatattcc aatcccaatc tgttgtcgga
    15661 ataccaggct tttttacaaa ttcacctaga gcatttaatt taaaagagga ctgtcctttt
    15721 attcctgttg aattaaattc ttgtctattt tcacctttgt attcacgaat aaattctgaa
    15781 cgataataat tcatcccaaa catcgtatta agaggtgcag ctcttttcat aatttctaaa
    15841 tcaccatctt caataataaa gctagaatta ttagcttcca atatttgatt taagtgaaaa
    15901 agcgtgtcat cactgtagta gcccaaaaaa gttccatcta atagaaattt attattataa
    15961 acatcatacc gtttagctgc caaaatattt tctttttgcc catcaatagg atagcctggc
    16021 tttaaagcat gaatacaacc tacctttccc tcaatcccta attgatgaaa ttcgaggact
    16081 gcaagagcat gcgccaacaa catattatga ttcgcttgaa ttgcttcaga taattgaaaa
    16141 tgatgattcg gaggaaactg acctcctata tattgacctg cagcaagaga catcagttca
    16201 ttgattgtaa accaatgctt gacttctgta aattcttgga aacaaaagcg agcatatcgt
    16261 atgaaacgat caatattctc tctattcaac caatcccctg tttctaacat tttctgaggc
    16321 gaatcaaaat gatgtaaaga aacaaacgga atcacattat gttttaagca ggactgaaag
    16381 actctatggt aatactgaac agccaatata ttcggctccc catctatatc aggaaatatg
    16441 cgaacccaag aaatagataa acgcaaagcc tgcaaaccat gttctgccgc caaggctata
    16501 tcttcttcgt aacgataata aaaatcacta gctggatctg gtaagaacgg actattttct
    16561 tgcaaataaa catcccacat atttattcct ttgccatcta ccctagttgc accctctact
    16621 tgataagcag cggtagcagc tcctaataaa aactccttcg gtaaggcttt aacctgtaaa
    16681 ttttccatga ctaatcctca ttgcaaacca atatgttctt caatctttcg aattcgttca
    16741 tattcatcaa taaaaaactt tacctgatca tacaatagca tcgttgtcat caaagtatct
    16801 tgaccatgaa tcatgataaa actcacttca aaattatctc cagatgcctc ctccgctaat
    16861 aaattagtct gttctcgatg ggcagacact attgagtcgt ttgcagactc aaccaattct
    16921 cttgcctgtt caaaatatcc atctctcgca aacgccaaag catccatcaa atctgacctt
    16981 gcatctcctg cgtaagcgac aattgtaaaa ccaagcatat ttatttcttc ttttgatttc
    17041 atctttcttc ctcctcaatc ttgatacatc ttttacacat cattattaaa atgacttcgc
    17101 tacgatacaa atagaaagtt gaccctaaat atcttaaaaa tccttaaatt tcataatatt
    17161 taggatcaat cttctctgaa taccttagtt cattttctat acttataatt tataagtgga
    17221 aaccagcgta attttttgct acttcaatta cacgataaac atccaaatta gattggaata
    17281 gcaattcgtg accacggata taattcaaaa catttctcca ttcatcttga gcttgccttg
    17341 tttttccagt tgcttgaaga tataaagcct tcgccatctt aacaacatat tcacgatgat
    17401 aactgagctg tttccattca tccttttgac tatttaataa cttagaaata ttttcctcaa
    17461 taattggtaa aaaattatca gctagattgt aagctatata ataatgattc gctaaaacat
    17521 cattttgacg gctgccaatt gcattaaaat aatcacatga ggaataacta gataattttt
    17581 ctaaatattc aacaacagac tgccaatttg acccatacaa agcagaaaag tattcttcaa
    17641 tcaattcttc ataacttctt gtcttcttcc agagcatttg ccccataaca taattaggaa
    17701 aattatgagg gaatccggca cgtaattctt gacacgaaat gtacccgttc aaatgtaggt
    17761 ttgaaagata agatacatct ttgtaaatag tttgactaat tttcatatag cctaaatcgc
    17821 cataatgagc acgccctaaa ggatagtcat atacgaaact atctccttta aatgtttttt
    17881 gccactcaaa aagataagat aaattttctt caagagaatt cggaagtata attttattac
    17941 gcagataagg tttaggcgta ggtatggaat tgtcaaaatc tacatctgca taactcattt
    18001 caaatgttct tgtaatcggt gcaaacatca tggtaaagcg ttcaggatta tctaattttt
    18061 ctttctgagg cgcccataac aactcatggt aaagtaggaa acaaatcttt gtatctaatc
    18121 cctcactcgt taaagcccta tccaattgat tgagaatacg aatatactga tccgaaacca
    18181 attcttgtct acagttttcg cattcacaaa tattattacg agcatccgac aaccatacat
    18241 gtaagtagtt aacatcaggt cttttcttgg cataatcctt aataatttct accatcttat
    18301 cagctacatc tggatttgaa aaatccaggc tggttaaaat cggagccgta ttaaacaatt
    18361 ctcgtttccc gtttatttca gcgacatagg gtttcttctc ctctgaaata ctaagacctg
    18421 attcccagcc aaattttgaa gagtaaccta aaacctcacc tgtccatcca tgaccaacac
    18481 gatgatgaat aagacctctt ttttgcaatt ctttatccaa cctatcactc aattcttgta
    18541 ctaattcatt tgagaatttt tctttattta ggtatggatt aaactcatgt tcataccaac
    18601 gtttcaaaaa agaataggga ttttcaaact gaatgaaaaa actgttcatc ccaatcttag
    18661 gtagccaatc aatgaaatct agtatatttt caaatgaatc tgctccctct atacatactc
    18721 ccctatgata gtaacttgct gtttcatcta tagatagctc tttatctaaa aaatcttcaa
    18781 atcttaactc tggaataaag tcatgtccgc gccctggtct agtatacaca acaccaaatt
    18841 catgaaacat tcggtaaatt ccaataagta aacctacaat tgtattggac tcaattctcc
    18901 ccttaccttt gtttaatgag atgaaaatat ggtcttttcc atcctcttca ttgactaatc
    18961 ctacaaaaat atccgcttcc ttctcctcga caagttctat atcggtatta aatacctgat
    19021 tcatatagta tcttaattcc tctaaggcaa agctagaata agtatttttc tgttgatcaa
    19081 atactctgat aaccatctta tttccctcca acagtagctt tttctttttc aagattgcgt
    19141 ttatctgcaa ttttgaagaa tggataataa attgctacag aaaccaaaat caaaacaact
    19201 tgtaatagag ctcctcgcca actagcccct gtcgcaagga agcctcctat gataggtggc
    19261 attgtccacg gaaggattac acctgttgta tagggtacta agcctacagc cattgataca
    19321 taggtaatca aggcattgat tgtaggagta gcaataaacg gaatcagcat aataggattt
    19381 aaaaccgttg gaaacgtaaa tagaatagct gtattgatat taaagataga cggtataata
    19441 gctagcttac ctaatgtttt attagcacga ctcttactaa ataggaagag acaaatcgca
    19501 agaccaatag tcgctccacc gccaccaata aatacaaata aatctttaaa cggtaatgta
    19561 ataatgtgtt gtagggtttg tcctgcagcc acagcttctt ggttttctgt agtaaattgt
    19621 aaccaaactg ggtctacaaa agcatttaaa acttgtcccc cattaactcc acagaaccaa
    19681 aagaatgagt ttacaataac acataaaatc atacctggaa gtgttcctgc aattaactta
    19741 agcggcgttc caacaattgc acctaaaagt ccgttgagac ctcctgcaac tcctgctgct
    19801 tccagacctt ttaagaccaa agcccacaaa acaaaagtag taaaaccagg taaaagagct
    19861 gaaaatgatt tactgaccac atctgggaca ccatttggca tttttatcgt aattccgcgt
    19921 tggataaaaa tacgataaat ctccgctgta accaatccaa tggtaatcgc cataaacaaa
    19981 gaagacgcat tcaggctaga aaatggtatt gcacctccaa ataactgctt gacctgctcc
    20041 ccatttttat cataaaccat acttgaaaaa cgaggggcca tcaatacaaa actggataag
    20101 gctatgatcc ctgcagacgg accatctgta ccatatcctt ccgacaacct gtaggcaata
    20161 ccgaaacaag cgaccaagga gataatcgct actgttgact gattcatagt tgtcaagata
    20221 cttagcaatc caacactatt cagccaattt gtaaaagcct cttgaggcca actgattaga
    20281 ataagaaata aagagccgac taaaatcaaa ggcattgcca tcataaatcc ttcacgaata
    20341 gctttcaaat gccgttgatt gccaactttt tcaccaaacg gagcgacttt cgtttctaaa
    20401 aacgttaaaa tattgttcat caccggaact ccttttttta ttttttataa attaaatata
    20461 ccactaacag aaagcgttgt caatatattt tttactgttt ttacaatatt tttttctttg
    20521 tatagaataa taattttaat tgattttttc ttatgtttaa tataaaataa accaaaggag
    20581 gaaacaaatg attacaaaac aatcagcctt tttacaaaat agagccacta tactggaatt
    20641 tctatatcga aatccagcaa catcccgtac agatattgtt aatgaaacag gacttactcc
    20701 agcaacaacg actaacatca taaaagagct aagcgaacaa tccctcatat acgaaactgg
    20761 tgatgaattt agcgagtttt ccggatctgg aagacgtaga aaaactattt ctattacaga
    20821 taatatccca tctgttgttg gaggtattga aataaacgtc ttaggtatct ttctcagtct
    20881 atgtgactta caagggaaaa ctcttttcga gacagaaatt ttgaatgaag attatcctat
    20941 ttcagaaatc aattccacca ttaccaatat gataaaaaca gctacaaagt atgtcccttt
    21001 ggagacaaaa ttacttggat ttggcttatc aatacctgga cattataaca aagactccgg
    21061 aagcatcatt acaaacaacc ccatatggga atcatttaat ttattaaatg taattaaaaa
    21121 attcgatttc ccttttattg taaaaaataa tatcgattgt atggctatag gacaatacct
    21181 ttttaaccca cacaataccc ccgataactt tattttccta cacgctggat taggtattta
    21241 cacttccttt ttcacaaaag aaaaaatagg agcctctaaa aatccttata tcggagaaat
    21301 tggacacacc attgtcgaat taaatgggca atattgtgaa tgcggaaaaa aaggttgttt
    21361 acaaacatat atttcggatg cttggttaat caaacatgcc caattattat ttaaaaattc
    21421 tcaactaact gtactaaaaa gccttgtaaa gactgaaaaa gacattcatt tagataccct
    21481 tttaacagct tacaacttag gcgactctgc tttacgccaa caaattgata aaggagtcaa
    21541 tttattggcc acttctattg caaatcttct cctcatcaat cctgctgata aaatctatat
    21601 caacagtcaa ttgcttaatt atcaaccttt cactcatgaa gtcagggata aaatccaaga
    21661 tcagctccac ttcgttccct ttactcgtaa tatagaaatt gaaattttac cttacaacaa
    21721 acatcgtgga agtataggag cttgtgcatt agctatcgtt gcttttttca tagagcatag
    21781 caatgtatta caagatatta tttcacctta atatattaga aatctataga cctgtttaaa
    21841 tcaactataa cctgtagtaa atatctcgta tttagacaat atgaaaacaa gacgacttcc
    21901 atataggaaa ccgccttctc gctatgctgc atgaaactgt aaaaatagat gaaagtgata
    21961 gcggtagtca aatcaagagg catcataact ctaaaaagtc acaatatata agttcatcct
    22021 cagaaaaata tcattctaat tattgaaatg cctacatgaa aagaaacgtt aaatgctcat
    22081 aaaacaagga atacaggtat caaaactgtg acaaaacaag tccctaaatt tactaaagac
    22141 actactcaac tttacacctg taaatggttg ttgtataata aagttacaaa gatgtacgac
    22201 cacactgttg taaatcatag tgttcgcgaa tatattactg atagcatttc tacaaataca
    22261 agtaaaggga ttggatgaga ttcaaacgaa atatgtcagt gttttggcat tcctagcctt
    22321 catatcattt aaagaattgt atagataaaa tttttcccaa tacagacact cgtaacaact
    22381 gcttcatttt tctaccaaca tatttaggaa caggataaga tacaagagga tcaatccata
    22441 aatcagttct ataccaatct aagacaaata agctaaaaaa acgattgata ataagcaaat
    22501 agattccaaa ttttctctat ctgctcattt taataaacaa tactagtgta actatccttc
    22561 cagtcagaag cttgtcaaat cacaccgaaa attcttctaa aatttatctc gttaggcaat
    22621 caagcaaaaa ctcaacgata gtacaaacat tatcatacag gattgacttc ctaaattata
    22681 tactttagta aggtttttgg ataagaaaaa aggttcattt tacatttcta aacactcttt
    22741 tctaatacga gataattaaa aaaactacat ttttaaatat aaactacaat aaaataaact
    22801 aaatgccata ggagaaagac aatggattgg tacgattata tgatacaggc atccaaacaa
    22861 tcacaattca acgcaagcca ttggtttcgc tatttgcgaa aagttatttt tgaagactat
    22921 tcttatttaa caaaccaaga tatagaaaag ttgctagact ccaaagaact aacccatttt
    22981 caaaaaatta gcttgaagta tgcctttcaa gagcatactc caactcataa atatgtgatt
    23041 tcattaaata aacctgctaa gttaaccaat gttcaaaaat tgatggagaa atacaagcat
    23101 ggataaaatg aaaccggtct tccaagcact aaataaggaa ttaattcagg aaaatctgac
    23161 tttaacaatt atctgtgtcg gtggttatgt cttagaatat catggtttgc gtgccacaca
    23221 agatgttgat gctttttatg accaaaatca gaaaatcaat gaaattattg ctcgtgtagg
    23281 aaaacagttt aatcttaaca cccacgaaga gttatggctc aacaatcatg ttgcaaatat
    23341 gaacaaacaa cctcccttaa gtttatgcga atccttgtac tcatttgaga atctgaccgt
    23401 tttagtagtc cctattgagt atgtgttagg aatgaagatg atgagtatca gagagcagga
    23461 tttgaaagat attggtgcaa ttattaaata caaaaacttt cattcaccat tcgatacctt
    23521 taaatattta aaagacatgg gatttgatac tattgacctc tctgttctat tagaaggttt
    23581 tagttatgct tatggtatgg attggttaga aaaatttttt aaagaaaatc aagataaact
    23641 tcgcgaattt tattaacagt atcaaacaag atgattgtca attagccagt cgtcttgttt
    23701 ttatgatgaa atgaaataaa atcggaacaa atcacttaga gaattccagt caatttctag
    23761 cactgtttga gacgtttcag cggactatag caaaatgaaa taagaatagg acaaatcgat
    23821 caggacagtc aaatcgattt ctaagaatgt tttagaagta aaggtgtact attctacttt
    23881 caatctatta tatttcagat tcggtccact attccttccc aaaaacattg catattgcgc
    23941 cgaaggaatt gctcatacta tcccaagcac aaaaccctca gtcgtttgac cgagggttcc
    24001 tttttattat tcaagaactt gaggctctat aatatttgta gtgggtaaat cccctatgga
    24061 tattatggag cctatttt
//
LOCUS       DAVLHM010000033        23378 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLHM010000033 DAVLHM010000000
VERSION     DAVLHM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.033"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(2..1981)
                     /gene="pknB"
                     /locus_tag="VXE45_001469"
     CDS             complement(2..1981)
                     /gene="pknB"
                     /locus_tag="VXE45_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0789487.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(1978..2718)
                     /locus_tag="VXE45_001470"
     CDS             complement(1978..2718)
                     /locus_tag="VXE45_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0789488.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(2733..4046)
                     /gene="rsmB"
                     /locus_tag="VXE45_001471"
     CDS             complement(2733..4046)
                     /gene="rsmB"
                     /locus_tag="VXE45_001471"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0789489.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVALKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(4039..4974)
                     /locus_tag="VXE45_001472"
     CDS             complement(4039..4974)
                     /locus_tag="VXE45_001472"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0789490.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPNRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(4987..7383)
                     /locus_tag="VXE45_001473"
     CDS             complement(4987..7383)
                     /locus_tag="VXE45_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0789491.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQVRILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTRNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(7449..7763)
                     /locus_tag="VXE45_001474"
     CDS             complement(7449..7763)
                     /locus_tag="VXE45_001474"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0789492.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(7788..8414)
                     /gene="gmk"
                     /locus_tag="VXE45_001475"
     CDS             complement(7788..8414)
                     /gene="gmk"
                     /locus_tag="VXE45_001475"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0789493.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(8544..10157)
                     /locus_tag="VXE45_001476"
     CDS             complement(8544..10157)
                     /locus_tag="VXE45_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0789494.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFERVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(10348..10602)
                     /locus_tag="VXE45_001477"
     CDS             complement(10348..10602)
                     /locus_tag="VXE45_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV0789495.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(10606..10860)
                     /locus_tag="VXE45_001478"
     CDS             complement(10606..10860)
                     /locus_tag="VXE45_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV0789496.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(11098..12195)
                     /locus_tag="VXE45_001479"
     CDS             complement(11098..12195)
                     /locus_tag="VXE45_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0789497.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTARSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIADQNFGRVPIRIETN"
     gene            complement(12205..12951)
                     /locus_tag="VXE45_001480"
     CDS             complement(12205..12951)
                     /locus_tag="VXE45_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0789498.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(13054..13407)
                     /gene="rsfS"
                     /locus_tag="VXE45_001481"
     CDS             complement(13054..13407)
                     /gene="rsfS"
                     /locus_tag="VXE45_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0789499.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(13420..13920)
                     /locus_tag="VXE45_001482"
     CDS             complement(13420..13920)
                     /locus_tag="VXE45_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0789500.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            complement(13921..14514)
                     /gene="yqeK"
                     /locus_tag="VXE45_001483"
     CDS             complement(13921..14514)
                     /gene="yqeK"
                     /locus_tag="VXE45_001483"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0789501.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVGKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(14514..15143)
                     /locus_tag="VXE45_001484"
     CDS             complement(14514..15143)
                     /locus_tag="VXE45_001484"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0789502.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVEYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(15195..15506)
                     /gene="yhbY"
                     /locus_tag="VXE45_001485"
     CDS             complement(15195..15506)
                     /gene="yhbY"
                     /locus_tag="VXE45_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0789503.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(15720..16826)
                     /gene="yqeH"
                     /locus_tag="VXE45_001486"
     CDS             complement(15720..16826)
                     /gene="yqeH"
                     /locus_tag="VXE45_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0789504.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(16829..17419)
                     /locus_tag="VXE45_001487"
     CDS             complement(16829..17419)
                     /locus_tag="VXE45_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0789505.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(17371..18279)
                     /locus_tag="VXE45_001488"
     CDS             complement(17371..18279)
                     /locus_tag="VXE45_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0789506.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(18336..18896)
                     /locus_tag="VXE45_001489"
     CDS             complement(18336..18896)
                     /locus_tag="VXE45_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0789507.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            19035..20243
                     /gene="sstT"
                     /locus_tag="VXE45_001490"
                     /pseudo
     CDS             19035..20243
                     /gene="sstT"
                     /locus_tag="VXE45_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            20311..21264
                     /locus_tag="VXE45_001491"
     CDS             20311..21264
                     /locus_tag="VXE45_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0789508.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            21409..21789
                     /locus_tag="VXE45_001492"
     CDS             21409..21789
                     /locus_tag="VXE45_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0789509.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            21888..22109
                     /locus_tag="VXE45_001493"
     CDS             21888..22109
                     /locus_tag="VXE45_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0789510.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            22126..22440
                     /gene="trxA"
                     /locus_tag="VXE45_001494"
     CDS             22126..22440
                     /gene="trxA"
                     /locus_tag="VXE45_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0789511.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            22747..23280
                     /gene="queF"
                     /locus_tag="VXE45_001495"
     CDS             22747..23280
                     /gene="queF"
                     /locus_tag="VXE45_001495"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0789512.1"
                     /translation="MKRQSALVVFSGGQDSKTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         6315 a         5473 c         4598 g         6992 t
ORIGIN      
        1 tttaaggagt agctgaagtt gttttaggtt tgtagattga aatcttgact ctagtcttat
       61 ttaggtctac cttttcacct gctctaggac tttgttcaac aaccatgcct tctacactac
      121 ctgcaggcgc tgtcgtcact tctacaactt ctatattagc ttccttaatc ccaacaattt
      181 gaatcaaatt gttcttagta aactccaagc tggaaccaat gtaactcggc atggcaacac
      241 ttgtaacttt tttagctact gtcaagacaa tttgagtagg tttactcaca tcataagtcg
      301 ttccggcacc tggactttgt ttcataatcg ttcctggttc gctttcgctg gactcttctt
      361 cctctatctt aatcaaattc tcaggaacct tcttctgctt gagttctgag attacttctg
      421 tagagttccg tccaatatag ttccctaatt gaatcgtcgt agctttttta gctactgtca
      481 aaacaatttg agttgccttg ctcaagtcat aggtcgtacc ttctggtaga ctttgcttca
      541 ggaccgttcc agcctcactc tcattcgact cttcttcctc aattttaatc aaattatctg
      601 gaactttttt ctcttttaat tccgcgataa catcagaaga tttccggccg acataattac
      661 taatttggaa ggattgtttg cctgatgaga caaccaaatt gattttcgtt ccttcttttc
      721 gaccagttcc agcgccagga tctgtacgga taatccgccc ttcttccacc ttttcactag
      781 cctctgtctt ctcctcacca atctcaaaat tggctttttt gagcgttgcc ttggcctctg
      841 caactgtctg acctgccaca tctggaatgg caatggttgc aggagttctg gatagtatcc
      901 aaataagaga agctgccacc aatacaaggc tggccaacaa aatcaggtaa cgcatcttaa
      961 atctatgttt tttcggtgct tgtggttggt aagtttcctc tgtcacagcc tggcttgggt
     1021 ttttgattga tttgtgttct gtctgcgctt gaaccttagg aatagatgtc aaggtactct
     1081 gagaaacctt cggcaaggtc ttggtatctg ccttgctcgt ttcatcaaag attaacttac
     1141 tttcatttct acgattgtag gacaagctac tagacaagtc cacatacatc tctgaaaccg
     1201 agcggtagcg attggtcaac tttttagcag ttgccttgat aataacattt tctaaagcct
     1261 gaggtacaga tggattttct gcaataacgg acggcagggg tttctggaaa tgctggaggg
     1321 caatggtcac cgcgctatcc ccgtcataag ggatatggcc tgtcaacatc tcatagaaaa
     1381 taatccccat ggcatagata tcactctgca cagtcgcctt cgaaccacgc gcctgctctg
     1441 gtgacaagta atgaactgag cccaacatcg agttagtctg ggtcagactt gtctctgcaa
     1501 aggctacagc aatcccaaag tctgtgacct tggccgtccc atctggtgtc aaaaggatat
     1561 tttgaggttt caagtccctg tgaacaattc ctcgagtatg ggccaagcgc atagccaaga
     1621 gaatttgtcc catgatacgg actgcttctt cattagaaag aggataatgt tccttgatat
     1681 agcgtttgag gtctagtcca gcaacatact ccattgcaag atactgttga ccgtcttcct
     1741 caccaatatc tgttatccga acgatatgag gatggtctag atctgccata gctctcgctt
     1801 cacgctgaaa acgagctaca gctatcgggt ccgtctggta gttggtcctc agaaccttca
     1861 ctgccacttc ttccccatct aagattaagt ctttggctag gtagacatcc gccatgcctc
     1921 ctcgaccaat ctgtttgaca atccgatagc gtccggcaaa aatcttgccg atttggatca
     1981 ttcttcatcc tcctcgttca tagaaacaag ggcaaccgta atgttgtcta aacctcctgc
     2041 attgttagca aaacgaacaa gtgtctccgt tttatctgct aaaggaatat cactggttac
     2101 aatatcacga atctcactgc ctgaaatcat gttggtcaag ccgtcactat tgagcaagag
     2161 atagtcacct gactcaagga taactgtccc aaaatcaggc tgaatttcat ctttttgccc
     2221 aatagactgg gtgataatat ttttttgcgg atgagcttct gcctcttctg gtgtcaattg
     2281 accagccttg agcaattcat taaccaaaga atgatcactc gtcaactgat ggtattcttc
     2341 tccacgaatc aagccgatac gcgaatcacc aatatgagca tagatagcct gattatcaat
     2401 aatagcaagg acttccaaag tagttcccat gcctctgtaa gcttcatcct gaccaagctg
     2461 gtgaatcttt tgattttcaa tttctaggta atgggcgaac cattcacgca cttcattgac
     2521 tgtatcgatc tgggtatcaa cccaagctac acccaggtct gtgaccgcca tttcactagc
     2581 gatattccct gcgcgatgac ctcccatccc atcagctaaa ataatcatgg tacgtccagc
     2641 tctattgaca tagtggttga catagtcttg gttatttgtt cgtttctgac caacatctgt
     2701 taataatgaa atttccatgt gtcagttcct tcctaatccg atatcttgcg aaattgactg
     2761 atgaagaatc catcacttcc atacaattca ggtgtaatga ggatacagcc gtctttcatg
     2821 atatccttac attcatgttc tagttttacc tgctcgaact cgggatgact ctctaaaaag
     2881 gccttaacga cttgaaaatt ctcctctgag acgatagtgc aggtgctata agttattata
     2941 ccacctttgc ctagtatttg acaaacacta cctaatattt ctaactgaat ttcctgcaag
     3001 gacgcgaaat ctgccgtttc tttattgtat ttgatatctg gttttcggcg caaaagaccg
     3061 attcctgaac aaggagcatc caccaaaatc ttatcaaagg aatcctggtc aaaaaactca
     3121 tgcacctttc tggcatccaa tttttgagtt tgaacccgat ctgcaactcc cagacgttgg
     3181 gcattttctt gaattaaatc caacttgtgg tcgtacaagt ccagagcagt aacctgacct
     3241 gtcgtaagat aagaggctat atgggctgtt ttcccacctg gagccgcaca ggcatcaagc
     3301 actcgctcat caccttgtaa atcaagcgtc ggagcaacca gctgactgga ctcatcttgg
     3361 atggtaatgg ctccattcgc aaacaaatta tgccctgcaa aatgcccctg ctccttaacc
     3421 agaccagtgg ttgctaaaag ggaattattc gcctccaaca aggcttggat ttcctctttt
     3481 cgacttaggt ctgttacacg aatactggct ttgtttcgca ctaacaggct ttcaaagatg
     3541 gcttttgctc tctcctctcc gtattcttcc ttgagtttgg caactagcca aactgggaga
     3601 gaataggcaa tggagtcacg cttgtttttt cgcttgatgc tagcaatatc tggccagcct
     3661 tcacgcaaga tacggcgaag gacagcgttg accaattttt cactgccttt tttacggagt
     3721 ttggccaatt ccactgcttc attgaccaca gcatgatctg gaatcttgtc caaatagcgg
     3781 agttggtagg cactcatgag aagaaggaca tagagccagc tgtctaactg gtctctgtct
     3841 tcgataaagt gggataggta ccattccaga gtcagtttaa gggctaccgt tccatagact
     3901 agctcggtca ctaagccctt gtctgctgca gagagctgac tccccttgag gtgtttattt
     3961 aaggcaatat ttgaatatgc ttgattcaca aaaacatcct ctagcactgc tagagctaaa
     4021 cttctagccg tttctacttt agtcaccaaa tcgttctcct acagtcaatg tacgtccaac
     4081 tccgttgagg aaggaagcaa tgtccatctt aggcttacca gctggctgca cttgtttgag
     4141 ggatagagcc ccttcagccg ttgcgacaat caattctttc ttgcagatag agagaatctc
     4201 acctggattt ccctgacctt ctactggtag ggcttcataa atcttaaagc ggtcgccctt
     4261 aaggaaagta tgggcaacag gccaggggtt cattccacga atttggttaa agagttgacg
     4321 attggttttg ttccagtcca gtttttcttc ctctggcttt atatttggag agaaggtaac
     4381 ctgactcgta tcctgcggtt caggtttgat atcaccagca atataggcag gcagagtgtc
     4441 caaaagcaaa tcacgaccaa ctagcgccaa tttttcaaac aaggtgccaa cattgtcctc
     4501 atctgtgatc ggaatgctgc gacgagaaat catatctcct gcatccattt ccttaaccat
     4561 ttccatgatg gtcacaccag cttcctcatc cccttgaatc aaggcataat ggataggcgc
     4621 accaccacgg tgtctaggaa ggagggaggc atgaacgttg acagcaaagt ccatgctatc
     4681 aaggagtttg cttgggagaa actgcccaaa agcagcagtc acaattccat ctgctcctag
     4741 cttcataaga tcttccatct ctggacttcc agataatttt tcaggttggt agatagatag
     4801 tcctgcttcc ttggcagcct gcttgactgg ggtttcttgg ataacttttt tacgaccaac
     4861 agcacggttt ggctgggtca caacggctag aatttcgtaa cggtcatctg tcaaaagtcc
     4921 ttttaagact gttgctgaaa agtcgggggt ccccataaag attagttttg tcatatcttc
     4981 tccttcttat aaaaattgct gcggctcatg gtcaatgctg agacggagct cactattttc
     5041 ccgttcttga gtcaaggcca agacctggtt gagggtcggc cccagctcat cttctaaacg
     5101 gtatttaatt aaaatctggt aatgatagag gttgcgggta cgggcaatcg gttttggcgt
     5161 tggccccaga atgggactgg tctctgacaa gcctgaccgc aaaatgttca tgacttcata
     5221 ggcacgtttg aaaacctctt cttctttctt gtgagaaagg gtaataccaa tcgtgaaata
     5281 gtaaggtgga tagccgagtt gtcgtctgat tcccatttca taggcataaa agccttcgta
     5341 atcttgatcc ttggcaaatc gaatagcata gtgctgcgaa ttgtaggact gtatcaagac
     5401 ttgacctgct ttttcagccc gacctgctcg acctgccacc tgagtcaaga gctggaaggt
     5461 tctctcagaa gaacggaaat caggcagatt caaggccgta tccgcattta gaactcctac
     5521 tagggtaaca ttgggaaaat ccaaaccctt tgcaatcatc tgagtaccaa gtaaaatatc
     5581 cgcttcccct cgcccaaact ggtcaagcaa ggcttggtga ctgcctttct ttcgagtcgt
     5641 atccacatcc atcctcaaaa tgcgaacttg gggaaagagt tctgctagct catcataagc
     5701 cttctgagtt cccgtcccat agtaacgaat actgtggctc ttacagttag gacagacctg
     5761 aggaatatcc ttcgagaaac cacaataatg gcagttcata gtcttggtat ccatatgcaa
     5821 ggtcagagaa atatcgcagt tgggacaagt atccaccgtc ccacactccc gacacatgac
     5881 aaagctagaa taaccacggc gattgagcat gagaaccacc tgctcttttt taaccagacg
     5941 gtcttggata gcctctagca aaggaggcgt aaagtttgac gtctcatttt gtccgatata
     6001 gtctcgaaag tcaatcactt gaacctcagg gattgtagcc aaaggattgg cacgttgggt
     6061 tagacgtaag tgttgataga cgcctttgcc agcacgtgcc cggctctcta agctcggcgt
     6121 tgcagatcca agtaccagag ttgcttgatt atactgagcc cgtaaaatag ctacctctct
     6181 ggcatggtaa cggggattgc tgtcctgctt ataagccgct tcatgctctt catcaataat
     6241 catgacaccc agatttttca gaggagcaaa gatagcagat ctggcaccaa caacaacttg
     6301 ggcatcgcca cgctccacct tgcgccattc atcatacttt tcaccattgg ataatcctga
     6361 gtgaagaatg gctaccttgt ccccaaaacg tgctataaaa cgctcggtca tctgaggagt
     6421 caaggaaatc tcaggtacca gcaaaatagc tgtcttgccc ttatccaggg caccttggat
     6481 aatctgcaag taaacctcgg tcttcccact tcctgtaatc ccttgaagta gaaagggagg
     6541 ttgagaactg ccaatagaac tcacaaccgc atcacgcgcc tgtctttgtt ctggatttaa
     6601 ctccaaaggt ctacttgctt caattccttc aaaataagca gccgagcgtt gaacttcctt
     6661 ttggactatg gtaacagcac cttgatccac aaagaagttg acttgctctc gcgagtagga
     6721 ctctaacaag ctagccaagg aagcgctctc tggatgagac agcagataat ctctcagttc
     6781 caactttttc ttggcacgtg tagaaatctc aacaccttct aattgagcat ggtcaacctc
     6841 ataccaagac tgggtcttga ccttcttttg atcgactgcc tgatattcca gaccaagcag
     6901 gccttttcta gtcaaacgca tcatttcagc ttgcttggca aggtctagtg aagaaaaggc
     6961 tagcgaatct tctgaaccaa acaggcgcac tcgttcttcc tgactcaagc cttccagagg
     7021 atagagaatc ttgtcatagc tagaattcag aaatcctgga agcatggcct tgaggataga
     7081 aattttgtag gagaagacag atttgcgtaa ctcctcagcc agccagagtt gttctggcgt
     7141 gagaacagga gaaaaatcca gcacctctgc aatatctttt aaatcttgct ccatctcttc
     7201 tccatctgat tgggactcca aaccaagaac aatcccttga atcaggcgat tacccttacc
     7261 aaaaggcaca tgaacccgca tcccaacttc cagcattccc tcaaattcct ccggaatcct
     7321 gtaactatag ggctggtccg tctgcatcaa gggcacatct acgataatct tagctagggc
     7381 catcttctca cctcctcctt gtcagtacat tcttgcaata gaaaaaataa gattgagtcc
     7441 ccccaacctt aaattttttc accatcttct ttttctttag caatttgctc tttgattttc
     7501 ttttcttctt cttctttgcg gcgtttttct tcttcgatac ggcgacgcac tgcttcgcgt
     7561 tttccttctg gatctgggtg aattgtaacg tttcctgatt cgatttcttc taaagcgcga
     7621 agagttgatt tttcagactt gaaaccttga gttgctgggg cacctgcttc caattcgtgg
     7681 gcacgttttg cttccaagat tacgagtgaa tattttgaag gaaccttgtc gagcaaggta
     7741 tcaatagagg gttttaacat catttgcttg tacctatttt ctaaatttta tcgggtagtt
     7801 ggagattttg gtaacatctc ctgatagtga ccaatgacac gatccacaca gaagtgttct
     7861 gcttcaatta cacatttgac acgttcagca gctaggggca cctgatcgtt gacaatggca
     7921 taatcatact cacgcatgag ggcaatttct tccttggcct tttcgattcg ttgggcaatc
     7981 acttctgcac tatctgttcc acgacctacc aagcgatctt gcaattcatc caaatctggt
     8041 ggtgtcagga agataaagac agcatctgga acctttttct tgacctgaag agcaccctga
     8101 acttcaattt caaggaaaac atcgattccc ttgtccaagg tttcattgac ataggtcaga
     8161 ggagttccat agtagttacc gacatattct gcgtattcca acatctgtcc ttgacgaatc
     8221 agctcttcaa attcttcacg agtacggaag aaatagtcga caccgtccac ttctccagga
     8281 cgttgtgcgc gtgtcgtcat cgatacagag tattgaaatt ggttttcaga actctcaaaa
     8341 atctctcttc taaccgttcc ttttccaacc cctgaaggac cagaaaaaac gattagtaag
     8401 cctcggtctg ccattgtgtc tccttttagt caatctgtga aataacattt ctctagaata
     8461 atggcaaaaa gccagattat cctttacagt ctttctatct agtgtaacaa aaaagcagta
     8521 atttttcaac tgctctttct tatttattta gcataatcta ctgcacgaag ctcgcgaatc
     8581 acggttacct tgatatttcc tggataatcg agattgtttt caattttctt acgaactttg
     8641 tgagccaaga ttgtgacttt gtcgtccttg atttttcctg gattgaccat gatacgaatt
     8701 tcacgtcctg cttgaagggc aaagctagtt tgcactcttt caaagccgtt agcaatttct
     8761 tccaaatcat ggagacgctt gatgtagctt tcaagagact cactacgagc acctggacgg
     8821 gctgcgctca aggcatctgc tgcagcgacg ataactgcta tcacgctctc agcttcaaca
     8881 tctccgtggt gactagcaat cgtattcacc acaactgggg gttccttgta cttacgggcc
     8941 aattccatac cgatttcaac gtggctacct tcaacctcat ggtcaatggc tttcccgata
     9001 tcgtgaagga atccagcacg acgggcaaga gccgcatttt caccaagttc gctcgccatg
     9061 ataccagcca acttagcaac ctcaatcgaa tggcgcaaaa cattttgtcc atatgaagta
     9121 cggaactgca aacgtcccat aatcttcatc aagtctggat gaaggtttgg cgcaccaatt
     9181 tcataggcag cagcctcacc gtattcacga atcttattgt caatctcttg acggtttttc
     9241 tcaaccaact cttcgatacg agctggatgt atacgaccat ctttgagcaa catttccata
     9301 gtcatacggg caatctcacg acgaatcgga tcaaatcctg acaaggtcac cacttctggt
     9361 gtatcgtcga taatcacatc gacccctgtc aaactttcaa aggtacgaat gttacgacct
     9421 tcacgaccaa taatgcgtcc cttcatagta tcgtctggca gatgaaccgt tgagtttgtt
     9481 gactccgcta catattcacc agcgatacgt tgcatagctt gaaccaagat gtccttggcc
     9541 attttgtcag aacgttcctt gacctcttgc tcagcttcgc gaatgcgact ggcaatctcc
     9601 ctggtcaagt tttcctctgt ctgagccaag ataatatctc gtgcttctgc ctgagacaga
     9661 gcaccaatac gctctagttc tgcttctttt tgtctttcga cttcctctaa ttgctcttca
     9721 cgcgcatcaa ggtttttcgc tctatcagaa atactttgtt ctttttgttc aagtgtttgt
     9781 tctttactcg tcaaattgtc gtccttacgg tcaaggctag tagctctctc tgtcaaacga
     9841 ctttcgattt gtttgagttc ttgacgttct gatttgaatt cagcgtccac ttcttcacgg
     9901 tattttctgg cttcttcttt ggcctccaat agtgcttctt ttttaagaga cttgctttca
     9961 cgtttggctt cattaacaag taaatccgct tcacgctcag cttgtccacg taaattagtt
    10021 gcttcttgtt cagcatttaa aagcatcaac tctgcagctt cctgagatga tttcatctta
    10081 gctgagatgc tgacatatcc aatgactaaa ccaatgatga cggcaaaaac agcaatcgca
    10141 agcgacatga tttccatgtt tttacctcat tttattgtta ttccgaatga catacattct
    10201 tttacattct accataaaaa agtgattttc acaaacctaa aatagaatat gttttgggga
    10261 atttggaaca catttgcaaa aataaacttg ttgtttagaa atagtagttt agtagagact
    10321 tgagaaaaag cctacctttc aatagactta gtaatgatct ttaaaggaca agaaagccac
    10381 gctatctcca tccatcatat aaatcaagcg attttctgca tcaatacgcc gtgaccaggc
    10441 tccttggtaa tcatatttga gtggttctgg tttacctatt cctgtaaagg gatcacgttg
    10501 aatatccttg attagtttat tgattctttt taacgttttc ttatcctgat tttgccagta
    10561 gcaataatct gcccaggcat cttctgtaaa cttgagcagc atttcttact cctcaataac
    10621 atggacctga gtacttccag cacgaacttg agccattcct cgcaaaacct tatcagaaag
    10681 ttccttattt tgagcaattc tcagggtttc ttggatacta tcccactcac tctttgaaag
    10741 gactacaatg tcctcatctg gatttttatt gaccaccgtc aaaggctcaa attcatcatt
    10801 taccttcttc atgtagtcct ttaaatgatt tcggaatgtt gagtaaagga ctgcttccat
    10861 aaccatacct cgttttagct cttttccact attatacacg aaaagaaaga aattgtcagg
    10921 aacttgtaca agattttctt ttctatctat ttatactcaa tgaaaatcaa agagcaaact
    10981 aggaaactag ccgcaggctg tacttgagta cggcaaggcg acgttgacgc gatttgaatt
    11041 tgattttcga agagtattat tcgtaaaaaa tctcaaaaag cctacctttc ggtagactta
    11101 gtttgtttct attctaatcg gcactcttcc aaaattctgg tctgctatac ttggatttcc
    11161 tagttggtaa atctggtctg ctttttgggt catagcatcc caaggttctt tgccaattcg
    11221 gctgactaga ctgacctgac ctttcaaaga cttgagatgt tgcctacctt tttcagtaaa
    11281 tccaaggaca tgaatgactt ctggcaagac attttctcta gcctgcatca aaatataggt
    11341 caataggcgt ctgacacgcg ccttggtgta acgtttggta gtcactaact cgaccaattc
    11401 ttccacagac cgggctgttt taatagcttc tttaatgcgc acagccattt cttgattgac
    11461 ctgatagatg gtggttaggt cgggatttga caagatttga tagcggagca agggaaaata
    11521 gtcttcccag atcaccttac tggcctgctc aaatagggca acagaaggca taaagcgttc
    11581 taagaaatct tggtccttct gatgttgacg gagggctgtc gccgaggcaa agtccacatc
    11641 tttattcaca gaatggtaac ctgccccctg acgctgaatc ggatgcagct tgatatttcg
    11701 tcctgcaacc gccttggcat aggccagagc aagaacatga ttgggggtat tacctgaaaa
    11761 atcaagacca gcaaattcct tccacatagc ttgggttttc tggggatagg aaagggaatc
    11821 aggcagattt tccacaaatt tctccatctc agcacctttc tctgtgtata agtcagcgat
    11881 tttctgataa tctcgaactt cctctgtccc aaaaactaga ctatcaatgc ccaagcgatc
    11941 caagatattc acagctcctt gaccaaagaa atcagctgcc tgaacactga ctaaaaaggg
    12001 caattccact accaagtctg cgccattttc cagcgccatc tgggcccttg tccacttatc
    12061 cacaatagca ggctctccac gctgcatgaa attccctgac atggcaacaa ttttcagtcc
    12121 ctctgcctga tccagcaggt atttatggcc attatgaaaa ggattgaact ccgcgataat
    12181 acctgtgatg gtcatgctaa tctcctactt ctgcgccaca aaaaaccaac gggtgctagt
    12241 ttctgttggt tccttatcct caaagtctgc atagagtttg aaggacttga atccagcctg
    12301 ttccagtaag atatcatagg tcaagatctc ataggtcctc tcctcatgta cttcatcgtg
    12361 gcgactaaag gaaccgtcag cctccttgat aaagaaagtc agctcatgca cgatggagtg
    12421 aggagcttcg tcctcatatg tatcccaaag catggcaaaa tcttccgcat tttcatggta
    12481 ggaatagcca gggaatactt catctgtctg gtaggtcgag tgcacgtcaa agatgaaaac
    12541 tccctcttca ttcagcgcat tgtacacgtc cttaaagacg tcccctactt ccacctcatc
    12601 ctgcatatag cagatagagt ccgaataaca cgtgacaaaa tcgtatttcc ctgccttgga
    12661 caaattcagc atgttacctt ctataaaagc aatcttttgc ttggctgaag ttgctctctt
    12721 ctccgcaatc ttcaacatat ccgcactcaa gtcaagtcca gtcacatcaa aaccagcctg
    12781 agagaagcgc actgattgaa ttcctgtccc acaagccagt tccaagagtt tctttttctc
    12841 cttggtctta ggcaaatgac gcagagaaaa attcgtccat ttgtcgtata aactatcgtc
    12901 catgaccgca tcatagaccg ccgcaaaggt ttcataagtc gccataatca tgatactaag
    12961 agctccatgg taaacaccac tagcccttta cctttctatc aatttttcta aaataagcaa
    13021 agaaacccag ttgactacaa ctgagttcat cttctaagca agagcttctg aaatatctac
    13081 tgaattcgcc tcatgccata gcttctctag attataatgg gcacgcattt cttctgaaaa
    13141 gatatgcacg acaacagcac cgaggtccag taagacccag cctccagctg catcgccttc
    13201 gacatggcta cctttaaagc ccgcttgagc tactttttca cggatattag ctgcgatagc
    13261 gtccaactga cggctattca ttgagctagt gatgacaaag tagtccgtca cactagtcaa
    13321 atcttgtaca tcaagtgcga ggatatcctc cgcacgtttc tcatcagccg ctttcacgac
    13381 tagttctagt aattcttttt cgttcattta atcctctttt tagaaaatat gtttgtaatc
    13441 taggacatct gcaaagtgct cctcccaaat gtcctcataa aattcattaa tcgtttctgc
    13501 tggaatgtca tccccatcaa aggttgtgac agcaccttct ggaacaataa gctgatagcc
    13561 atattcaaag gcaaccttga cagaggtatc cacacaatat tctgtctgca taccacataa
    13621 aactaatttt tcaatcccct gtttatccaa gtattctttt aagccagttt ctttgaaaat
    13681 actgttatac ttcttctgaa agaccttttc agcaggtttt cgatttaaaa gcgcagataa
    13741 ctgccaatct tctgatgttt gagcttcaga attctcaata tgttgaacat agataatttc
    13801 aatattcttg cttctagcct ggttttgtaa ataagaaatt ttttccaata gactttttgt
    13861 ctggaaccca gtttctacta aaacattctg aacatcaatg attataaaag ccgtcttcat
    13921 ttagtcctct ttcaaatagt gcacaaaggc gttataggtt tcaagggttt ggggatagat
    13981 ggggaatccc tgatgagcta gatactccac ggtacgagct gtttcgtagg ccaccgcctt
    14041 attgagcgat agacttgcaa tctcacgcgc cacatctact ccaggaaagg ctcgattgtg
    14101 ctcgatatag tctgcgacgt agatgacctt atctaggtct gtcatttgac cagctccgac
    14161 tgtatgaatt tcaatggctc gcagaatttc agaatcatgc aaatccaaat cttcctgaat
    14221 tttgtaaatt ccgaccatac catgccagac attattgccc cagtttttga ggtcagggtc
    14281 tagctggtaa cggtcaatca aggctagaaa ttcctgattt gacaactttt tagcatagtc
    14341 atgaagaaga cctgctagac ttgctttccc aacatctaca ccaaagcgct gagctaattc
    14401 catagcggca cgctccacac ctagacaatg ggttagacgt ttctcaggta gaagctctgc
    14461 cattttttcc aacaaggcct cacgggagca gttgatatag tcttgatagg acatcagtag
    14521 agcccctcct tctcgatgta gtctagcact ggctgaggta ggagaaagtt gggtttccga
    14581 ccttgggcaa ggaagtcccg caccatgctg gacgagatat ccatgagcgg tacgtccacc
    14641 cagataactg gataggaagt ccctaccttg tagcgtggac gctgaacccc cacaaactga
    14701 accatgtcaa ccagttcatc aattcggtac cacttaggca gatactcaac catgtcggca
    14761 ccgatgataa agtaataatc cgtatctgga ttcttctctg tcaaaatctt catggtgtcg
    14821 taggtgtagg aaataccctt gcgctccaac tcaatggttt caatgactag gccgtcaatt
    14881 ccctcaattg ccaactcaag catcttgaga cgatggtgtt cagggatggt ttccttttta
    14941 tcaacgtgag gaggttggta ttcaggcatg agaagaactt gatccagtcc caactgttgc
    15001 cgtacttgat ccgcaacaat gagatgggca ttgtgaacag ggttaaaatt cccccctaaa
    15061 atcccaactt gtttgcgttt tttctccttg atttctggct ccaactctac cttggtaaag
    15121 ggagtcaata gttcgattgt cataggctag tcccctttat ttctctataa aaacagttat
    15181 ttggagtttc ggtcttagat ttctttgact ttcttagaaa tcttgcgatt ttctttcttg
    15241 ctagattgtt taaacaaaat caagatgcgt cctatttttt ggactgtatc cacaccgatt
    15301 tcttcttcca aaatttcagc tacttcgtgg atgttttcat ctgtgttttg taagagagta
    15361 accttgatta attcacgcgc atcaagagct tgacggacgc tggttttgat ttggtcgttg
    15421 agtccatttt tcccgatttg gatgataggt ttgagggtgt gtgcctggct gttgaggaag
    15481 gcacgttgtt ttgatgttaa tgacataatt ttcttccttg tttttggata gttattttag
    15541 gtggtgaggg acggtcggaa ctaattttcc aaagatttca tctttgaaaa atggatttcc
    15601 tgacctcaca attgagcctt ggtctcaatt gtgccccttg ccaatctaca gattggcaat
    15661 cacaccacgg caataactat cgctatatga gctcactttg ttcgctcagc gattttgttt
    15721 taaataattg cttttcgtgt gacgacggcg acgccttctg gtgcccagac ggcgactttt
    15781 gctatgcctg ttacacgaat ccagcctagg cctgagatga ctaggtctgt cttatcttta
    15841 atggtaaaga catgctggac tagccttggg aaatcttctt tttccttgct atttggtggt
    15901 gtcagaagag ttcccaggtg cttatcgtag aaagcactag ctccttcaag cttgctacga
    15961 tggagtttga gttcattatc aaagaaagca gtaaatcctt gcttttctcc tgctataaag
    16021 tcaaagcgtc ccaaaccacc taaaaatagg gtttgctcag gattaagctg ataggtctta
    16081 ggcttgattt cctttttagg actgacatac ttgaggtttt tggccgtcaa gtagtgagcc
    16141 atctggtggc ggtggataat tcccggcgta tcgtaaatat aagatccgtc gtcaagcgga
    16201 atctctattt tgtccaaggt tgtacctggg aagcgtgaag tagtgatgac attctgatca
    16261 cccgtgattt cttggataat agcattgatt agagttgatt ttccaacgtt ggtcacaccg
    16321 accacataga catcgcggcc cttacggtag tgttcaatct tgtcaatgac ttccttaatg
    16381 gcatgtttat tttgtgctga agttaggacc acatcgactg gacgaagacc ttcttcatgg
    16441 gcacgtttca tgagccactg gctaatctta ccagacttaa ctgacttagg aaggatatct
    16501 tttttatttc ctaccaagag gacatcattg cccgagacga aacgtggtaa acctgggatg
    16561 acagatccat taaaatcaaa gatatcaatg acattgacca ctaaggcatc actgtctccc
    16621 acctcgtgca agagcttgag gaaatcatcg ttcgtcaact ggacatctgt gatttcattg
    16681 tagtggcgga gacggaaaca gcgttggcaa tagacttcgc cagtctccaa acctttttca
    16741 agtgccgact ggggggtaaa accaagacca gctttatctg tcgtctgaat ggttgctcca
    16801 caaccaatac agagaatttc ttccatagtt aaattccttt tttatatgta atcggtccgt
    16861 acttttcagt gatttttctc ataacacgac gctcacgagt tcggttaatc tgcgttttga
    16921 ttgagtcatg ttggaccaag ggtttgacta aaattgaccg aatccctgca cggtgggctg
    16981 ctcgtatatc tgtcatgagc tggtcgccaa ccatgaccac ttcctttttg tcatagtgga
    17041 attccttcat agcacggtca ataccaaatg tgaagggctt caaggcccag taaacgtaat
    17101 caatcccaaa tttctcaact gctcgttgaa cgcgtttttt ggtgttattt gacactacga
    17161 taatgccaat acccgcgtcc cgaaggtcat gtagccattg cttcatctct ggcgttccat
    17221 cagggttgtt ccaagcaatg agggtattat ccaaatcgac caaaacagcc ttgattccct
    17281 gcgcctgcag gcttgggact gtcagatcat agactgcttc cacagcaaaa tctggtatat
    17341 aattttcaat cgccattctg gctccttttc ttaacttttt ttcgcaattt tccttagtaa
    17401 caaggataaa acaatccaca aacctgcact agccaaactg atatagagcc aagcatgggg
    17461 ctcatctgtt aaaggtaagg gaacattcat tccgaaaaag cctgtcacga ctgccaaaac
    17521 agctagcaag actgaaatga tagtcaaggt tgtcaaattg tcattcagat tattgtttag
    17581 aatattgttg taagaggctg aaagctgctg taaaatctga gagattaggt ctgtcatgga
    17641 taccagctga tgagcctcaa tcatggcatc atcaaactgt tctctctcaa tctcatcaaa
    17701 actacgatac aaggcatgac cttgaatatg ctctaacaaa atccgatttt gtttggcagc
    17761 tgccgtcaga taaaccatac cagtctccaa atcagacagg gcaaagaggt ttttcttggt
    17821 agttcgctgg cgcaagaggt cattgacctc atccctactc ttgtccatct gctcaatgac
    17881 aggatagtag gcattgctga taatttccag actggcaaag agaaacttat aaatcgaaag
    17941 cgtgtcatgg ctctccagat aacgagtcat ctgttcaatg acataggcgt tcttggtatt
    18001 actaatggta atcaggcgac gatgctcgac aataaaggtc atgggaaaag tctcatagta
    18061 ggccttgtcc ttttttacgt ctaggacatt atagataaag gtaaccgtcc cactttcacg
    18121 gtggtaatcc atgtgggcgc gctcgtttct atccagtgcg tattcaatgg tttccttgtc
    18181 caaaccgtaa atttcagaaa ggtcttctag tttattcaac tttcctaggt ctaggtctat
    18241 ccaggtacaa ccattgccca actgcttttc taaaaccatc ttttctcctt attaaactcc
    18301 ctctattgta ccacaaatta cttaaaataa caggtctagt ctgtgcgtga gaaattgcta
    18361 acaactgtga tatttcggtt agggacaaag tgaagggctt gctcctcgct acgaagctgt
    18421 gtcgtacgaa ttcccacact gacaacctta cccgatacag taatcggtcc atttgtcaga
    18481 acgacctcat ctcccacatc cagttgacgt tcaaagagga tgaaaaagcc attgatgaca
    18541 tcagacagaa agccttgggc tcccatacca atcgctaccc cagcaatacc agctccagcc
    18601 agcaaactag aaactggcaa acctaaaatc gacaaaatgc agtagagtaa aaagaaatat
    18661 agcgtataat taaacacatt ttctagtaaa cgtgagatgg ttttttggcg tccgacatca
    18721 tgacgagaca tttttagaga aggtttgaca attctctgca ccatggtatg aagcattttt
    18781 ttagcaatat aaaatacaat caaaagcagt aaaagagaaa tgaccttggt tagaatattc
    18841 tcgataatgg ttgtcacatc tagcttttca atataagcct gaataaattt ttgcatataa
    18901 aactccttta tttcattata ccatattttc atcagtctca ttctccataa atattcaaaa
    18961 aatagacaga aaattcttga ttttgtctat catttatact ataatcataa tcactacaca
    19021 aaaaggagat tattatgaaa agaatcattc atgcttggaa taaggcaagc cttgtcaagc
    19081 gtatcttgat tggtatgctt tgtggggaat cctaggactg acccttccta atctctcagg
    19141 gattgggcta ctcggggatt tattcgttgg aggtctaaaa gctgttgctc ctatcctagt
    19201 ctttgccctc gttgccaatg ccctttccaa catcaaaagg gacaagatag caatatgaaa
    19261 actgttgttt tcttgtatat cctatgatag ggactttcgc cgctgctctt gtagctgtac
    19321 tagcaagttt catcgtccct attgaaatta ccctaaatag tgccaatact gaaattgcac
    19381 caccagatgg gattgggcag gtcctcagca acctcttgct caaactggtt gacaacccag
    19441 tcaacgccct gcttactgct aactatatta gaatcttatc ttgggcagtc atttttggaa
    19501 tcgctatgag agaagccagt aaaaatagta aagaattgct aaaaactatc gctgacgtga
    19561 cttctaaaat tgtcgaatgg atcatcaatc tggctccatt tggaatcctt ggtcttgttt
    19621 ttaaaaccat ttctgacaag ggagtcggaa gccttgccaa ctacggtatt ttattggttc
    19681 tattagtaac gactatgctt tttgttgccc ctgtggtcaa ccctttgatt gccttcttct
    19741 ttatgagacg caatccttac cctctagttt ggaactgcct ccgtgtcagc ggtgtgacag
    19801 cctttttcac tcgtagttct gcgactaaca ttcctgtcaa catgaaactc tgccatgacc
    19861 ttggactcaa cccagatacc tattctgttt ctatcccact cggttctact atcaatatgg
    19921 ctggagtagc gattaccatt aacgttttga cccttgttac agttaacact cttggaattc
    19981 ctgttgactt tgccacagcc tttgtcctca gtgtggtagc agctatctca gcctgtgatg
    20041 cttcaggtat tgccggaggt tccctccttc ttatcccagt tgcttgtagc cttttcggta
    20101 tttctaacga tattgccata caaattgttg gggttggttt tgtgattggt gtcatccaag
    20161 actcatgtga aacagccctt aactcttcta cagatgtcct ctttaccgcc gttgccgaat
    20221 acgcagcaac ccgtaaaaaa taactcatca aggcaagcct gctcatgtct tgtcttttac
    20281 gcttttattc taacttatta ggaaattctt atgtctatta gccaacgtac gaccaagctc
    20341 atcttagcta cctgtcttgc ctgcctgctt gcttattttc tcaatctttc gtcagcagtt
    20401 tcggctggaa ttatcgctct cttgagccta tctgatacgc gtagaagtac tttaaaactg
    20461 gctcgcaatc gtcttttttc tatgcttcta gctctggcta tcggcgttct agcttttcac
    20521 ttgagcggat ttcatatctg gagtctcggc ctctatctgg ccttctacgt tcctttagcc
    20581 tacaagatgg gctgggaaat tggcatcaca ccaagcacgg ttttggttag ccatctcttg
    20641 gttcaagagt caacctctcc agacctccta gtcaacgaat tccttctctt tgctattggt
    20701 acaggatttg ccttgcttgt taatctctat atgccttcac gagaagagga aatccagcac
    20761 taccacacgc tggtggaaga aaagttaaaa gatatcctcc agcgcttcaa atactattta
    20821 tccagaggag acggacgcaa ccgagcacag ctggtagcag aattagacac gcttttgaaa
    20881 gaagccctca gactggtcta tttggatcac tctgaccacc tctttcacca gaccgactac
    20941 catatccact actttgagat gagacaacga caaagtcgta tcctgagaaa catggcccaa
    21001 cagattaaca cttgtcacct tgccgccagt gaaagcctga tcttagcgca actcttttca
    21061 aaaattgcag gtcaactgag ccagaccaat cctgcttctg atttgctaga tgaaattgaa
    21121 cgttatctgg aagtcttccg gaaccgcagt ctgcccaaga caagagaaga gtttgaaacc
    21181 cgcgccactc ttcttcaact cctacgtgaa gccaaaacct tcatccaagt aaaagttgat
    21241 ttttaccaaa aatatagaca gtaaaaaaga aaaccactaa aaaacagagc ttgccagcat
    21301 tcttgaaaag tagtataatt attgcatgcg caatcatctt atgacgcaaa gactgcccgt
    21361 taatggactt tcttctataa ttatgactct aaaaagaaag gagacactat gacctatttg
    21421 gaaaaatggt ttgacttcaa tcggcgtcag aaagaaattg aaagtctctt ggaagagacc
    21481 attgcccaac agagcgagca aagtctgacc ttgaaagagt tctacctgct ctactatctg
    21541 gacttggctg aagaaaaatc tctacgccag attgacctgc cagataagct tcatctgagc
    21601 ccgagcgcag tttctaggat ggtggctcgc ttggaagcta aaaattgcgg tctactcagt
    21661 cgcatgtgtt gccatcaaga tagacgctct agttttatct gcctgacaaa tgatgggcaa
    21721 aagacactgg cctcgctaca aaagactgtc gaagaaagct tggaagcagg tttggatttc
    21781 ttgatttaag atgattttaa aaaaagttgc gtgcgcaatc atttttcttg acattctctt
    21841 ttataaggag taaaataaag ttagcattaa acaaaggagt tttaaacatg attgaaatta
    21901 cctatataga tgccagcaag aacgaaagaa ctgtgacttt cgagtcttat gaagactttg
    21961 aacgttcgca acaagcttgc cttatcggcg tcgcagacta ctaccctgtc caaaaattaa
    22021 cttacaaggg tcataatttg gactaccatg ggacttatgg agatatcttc ttctatctca
    22081 tgaaacaaga tttaagccaa tataactaaa aaaaggagaa atacaatggc aaaagcaatt
    22141 acagatgcaa cattcgaaca agaaacaaaa gacggtttgg tcttagtaga cttctgggca
    22201 acttggtgtg gtccatgtcg tatgcaaggt ccaatcttgg acaaattgtc tgaagaactt
    22261 tcagaagatg tcttgaaaat cgttaaaatg gacgttgatg aaaatccaaa cacagctcgt
    22321 gcttttggaa tcatgtctat tccaactctt ctcttcaaaa aagacggcca agttgtcaaa
    22381 caagttgcag gtgttcacac agcagaacaa atcaaggcca tcattgctga attgagctaa
    22441 tcaaacgaga gaccaagtac tttctttggt ctcttttttc ttgccctttg ccatttttca
    22501 aaagatatgc tagactatag tagattgaaa ctagaatagt acatctctac ttctaaaaca
    22561 ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct gttcttattt cattttacta
    22621 tataaataga atattacgat atttgggata tgccatcgct aaaaaaaacc tcgatttggt
    22681 attttttagc tccctaatgg gagcttttta cgtgctctga acatttccca ttttggaagg
    22741 agtactatga aacgtcaatc agccttggtc gtctttagtg gtggtcaaga ttcaaaaacc
    22801 tgccttttct ggaccatgca acactatgaa acagtcgaag ctgtcacctt tgcctacggc
    22861 caacgtcatc acctcgaaat tcaaattact agagaaatcg ctaaggaaca gggcattcgt
    22921 caccatatcc tcgatatgtc tctgctggga caaatcactg ctcagccaga ctttgcgacg
    22981 attcatattt cctacattcc tgacaagctc tgtgtcgagt caaaatccct caaactatat
    23041 ctatttagct accgaaacca cggagatttc cacgaaaact gtatcaacac catcgggaaa
    23101 gacttggtca acttgctaga ccctcgctat ttagaagtct ggggaaaatt cactccgcgc
    23161 ggtggcattt caatcgaccc ctactataac tacggtaagc aaggaactaa gtatgagggc
    23221 ttggcagaac aacgcctctt ccaacacgac ctttatccag agaaaattga caaccgctaa
    23281 agtcatactc aatgaaaatc aaagagcaaa ctaggaagtt agccgcaggt tactcaaagc
    23341 agtgtttgag gttgtagata aaactgacga agtcagct
//
LOCUS       DAVLHM010000034        23135 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLHM010000034 DAVLHM010000000
VERSION     DAVLHM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.034"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            178..1659
                     /locus_tag="VXE45_001496"
     CDS             178..1659
                     /locus_tag="VXE45_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0789513.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2021..3022
                     /locus_tag="VXE45_001497"
     CDS             2021..3022
                     /locus_tag="VXE45_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0789514.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3173..4090
                     /locus_tag="VXE45_001498"
     CDS             3173..4090
                     /locus_tag="VXE45_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0789515.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4101..4991
                     /locus_tag="VXE45_001499"
     CDS             4101..4991
                     /locus_tag="VXE45_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0789516.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5020..6636
                     /locus_tag="VXE45_001500"
     CDS             5020..6636
                     /locus_tag="VXE45_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0789517.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6646..7965
                     /locus_tag="VXE45_001501"
     CDS             6646..7965
                     /locus_tag="VXE45_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0789518.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8176..8248)
                     /locus_tag="VXE45_001502"
     tRNA            complement(8176..8248)
                     /locus_tag="VXE45_001502"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8213..8215),aa:Lys,seq:ctt)
     gene            complement(8513..9784)
                     /locus_tag="VXE45_001503"
     CDS             complement(8513..9784)
                     /locus_tag="VXE45_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0789519.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10054..10254
                     /locus_tag="VXE45_001504"
     CDS             10054..10254
                     /locus_tag="VXE45_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789520.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10458..10637
                     /locus_tag="VXE45_001505"
     CDS             10458..10637
                     /locus_tag="VXE45_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789521.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10774..10953
                     /locus_tag="VXE45_001506"
     CDS             10774..10953
                     /locus_tag="VXE45_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0789522.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10990..11442
                     /locus_tag="VXE45_001507"
     CDS             10990..11442
                     /locus_tag="VXE45_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0789523.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11733..12203
                     /locus_tag="VXE45_001508"
     CDS             11733..12203
                     /locus_tag="VXE45_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0789524.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12222..13310
                     /locus_tag="VXE45_001509"
     CDS             12222..13310
                     /locus_tag="VXE45_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0789525.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            13291..13449
                     /locus_tag="VXE45_001510"
     CDS             13291..13449
                     /locus_tag="VXE45_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV0789526.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            13559..14593
                     /locus_tag="VXE45_001511"
     CDS             13559..14593
                     /locus_tag="VXE45_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0789527.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14655..16838
                     /locus_tag="VXE45_001512"
     CDS             14655..16838
                     /locus_tag="VXE45_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV0789528.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            16889..17905
                     /locus_tag="VXE45_001513"
     CDS             16889..17905
                     /locus_tag="VXE45_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0789529.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            17920..18870
                     /locus_tag="VXE45_001514"
     CDS             17920..18870
                     /locus_tag="VXE45_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0789530.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTVLA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18872..19615
                     /locus_tag="VXE45_001515"
     CDS             18872..19615
                     /locus_tag="VXE45_001515"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0789531.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19626..21422
                     /gene="pepF"
                     /locus_tag="VXE45_001516"
     CDS             19626..21422
                     /gene="pepF"
                     /locus_tag="VXE45_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0789532.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            21669..22223
                     /locus_tag="VXE45_001517"
     CDS             21669..22223
                     /locus_tag="VXE45_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0789533.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            22334..23002
                     /locus_tag="VXE45_001518"
     CDS             22334..23002
                     /locus_tag="VXE45_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0789534.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7342 a         3801 c         4894 g         7098 t
ORIGIN      
        1 tgtattcacg ccctcaatag acggtaaaat aagaaaattg tttatatatt gtctccgtag
       61 tgttattata cgaaataaaa gattttagga aaagtcgtta tatcatgcta tacctattct
      121 ttgtggtata attgcaagag gtttaatccg ataatttata aagagagaaa gatattcatg
      181 agagatttat tatctaaaaa aagtcatagg caattagaat tattagaatt attatttgaa
      241 cataaacgtt ggtttcatcg ttctgaacta gcagagttat taaattgtac agaacgtgca
      301 gtcaaagatg atctatccca tgttaaatct gcttttcctg acttgatttt tcattcttct
      361 actaatggta tacgcattat taataccgat gatagtgata ttgaaatggt ttaccatcat
      421 ttctttaaac attcaactca tttttcgatt ttagaattca tcttctttaa tgaaggttgt
      481 caagctgaga gtatttgtaa agaattttat atcagttcat cttcgctcta tcgtattatt
      541 agccaaatca ataaagtgat taaaaggcaa tttcaatttg aagtcagtct gacccctgtt
      601 caaatcattg gaaatgagag agacattcgt tacttttttg cacaatattt ttcagaaaaa
      661 tattatttcc tagaatggcc atttgaaaat ttttcatcag agccactatc tcaattgtta
      721 gaattggttt ataaggaaac aagctttcca atgaatttgt caacgcatag aatgctaaag
      781 ttgctcctag ttacgaacct atatagaata aagtttggtc attttatgga agtagataaa
      841 gattctttta acgaccaaag tttggatttt ttaatgcagg cagaaggaat agaaggtgtt
      901 gctcagagtt ttgaatcaga atacaatatc tctttagatg aagaagttgt ttgccaatta
      961 tttgtgtctt actttcaaaa aatgtttttc atagatgaaa gtctctttat gaaatgcgta
     1021 aaaaaggata gttatgttga aaaatcttac catctattga gtgattttat tgatcagatt
     1081 tcagtcaagt atcagattga aatggagaat aaggataatc tgatttggca tctgcataat
     1141 accgcacatc tgtatcgtca agagttgttt actgagttta ttttatttga tcaaaaaggg
     1201 aatacaatca ggaactttca aaatattttt ccaaaatttg tttcagatat aaaaaaagag
     1261 ctttctcact atttagagac tcttgaggtt tgttctagtt caatgatggt aaatcatcta
     1321 tcttatacct tcatcactca taccaaacat ttggtgatta atttgctaca aaatcagcct
     1381 aaactaaagg ttttagttat gagtaatttt gatcagtatc atgcaaaatt cgttgcagag
     1441 acactttctt attactgtag caataatttt gaactggaag tttggactga attagaatta
     1501 tcaaaggaat ctttagaaga ttcaccttat gatatcatta tttctaattt tattattcct
     1561 cctattgaaa ataagagact catctattca aataatataa acacggtctc actcatatac
     1621 ttgttaaatg ccatgatgtt tattcgatta gatgagtaac caaaaataac aaaaaaacgc
     1681 tatttcgcgt ttgaactgta cctcaaaagt tagacagaaa aaatctaatt tttggggtgt
     1741 ttttgttaag aaaagacctt caatcattta agcaaaatgt acatctagat ttatagccct
     1801 ctaaaactct tgcttttttt gtagaagata cgaaaaaagc cataaaacca aggcttttcc
     1861 tgttttatgt agatgtttac acatgaaaat tgaagtattt tcaaaagcta attggagtga
     1921 ttttattcat gatgggataa atgatctggc caaaaatgat tgagaaatag ttgcttaaaa
     1981 agcatttgca tgatactata tattgaaagg aggtgataat atggtagaac aaagaaaatc
     2041 aattaccatg aaagatgttg ctttagaagc aggagttagt gttggaactg tttcacgtgt
     2101 aattaataaa gaaaaaggca ttaaagaagt aactttgaaa aaagtggaac aagcgattaa
     2161 aactttgaat tacattccag attactatgc tagaggaatg aaaaaaaatc gaacagaaac
     2221 gattgcaatc attgtaccaa gtatctggca tcccttcttt tcagaatttg ctatgcatgt
     2281 ggaaaatgaa gtctataaga gaaataacaa attactctta tgttctataa atggtacaaa
     2341 tagagagcaa gactatctgg agatgttgcg tcataataaa gttgatggag tggttgccat
     2401 tacctatagt ccaattgaac attacttgac gtcaggaatt ccctttgtta gtattgaccg
     2461 cacatactca gatattgcca ttccttgtgt ttcatcagat aatgatgcag gtggaagaga
     2521 agcagctaaa caattaatta gtaaaggatg tcagcattta gcctttgtgg gcggacataa
     2581 tacaaccatt aatgaaacca aacgtcgtag aatttcattt gaaaagtatg tccaagagca
     2641 taaaatacct cttagtattt ttgatttgga tgagacagtt actgactatt atggaaagct
     2701 agagagtttc ttggaagaaa attcttctat agatggaatt tttacaatca acgattttac
     2761 agctttggat gtgattgaaa tactagaaaa aaatggcaaa cgtattcctc atgatgtcca
     2821 aattattgga tacgatggaa ttaaaatggc tggagataga gattatctac tttcaactat
     2881 tgaacaacca ttggaagaaa tggcaaaaga agcggttcgt attttgtttg atataattga
     2941 tggaaagact gttaatttgc agacaatcct accagtaaaa tttgttgaag gaaaaacaac
     3001 aaaaaatgaa aataagtctt gacagaaagc gctatcaatg atagaatgaa ttcagataaa
     3061 aagatttatt tttaaaacaa aaatgaaacg tttcaaaaaa agaaataaaa agacagcgcc
     3121 aagcgctatc ttttatagaa aaaatgaaac gtttcaaaaa aaggaggttg ctatgaatag
     3181 caaagcgaag caagtttctc tttgggaaag aatcaagaaa caaaaactct tgttattgat
     3241 gactgtcccc ggtttagttt taacctttat ctttaaatac atccctatgt atggggtttt
     3301 aatcgcattt aaagattaca atcctttaaa aggaatttta gggagtgatt ggattggttt
     3361 ttctgagttt acaaaattca tatcctctcc caactttggt atcttgttag ccaacacatt
     3421 aaaattaagt atctatggtt tattgcttgg ctttttacca ccaatcattc ttgcgattat
     3481 gctcaatcaa ctcttgagtg aaaaagtcaa aaaacgaatt cagctcattt tatacgcacc
     3541 aaactttatc tcagtcgttg ttattgtcgg tatgattttc ctcttctttt cagtgggagg
     3601 accaatcaac aattttcttt ctatgtttgg aatgaaggct gacttcttga caaatccaga
     3661 cttctttaga cccttataca tctttagtgg tatctggcaa ggaatgggct gggcttcaac
     3721 gctctacacg gcaacattgg taaatgtaga tccagcctta gtagaagcag ctcgactgga
     3781 tggagccaat atcttccaac gaatctggca cattgatatt ccagctctta agcctattat
     3841 ggttatccaa tttgttttag ctgcaggtgg aattatgaat gtcggatatg aaaaagcatt
     3901 cttgatgcag acatcgttaa atttgccaac ttctgaaatt atctcgacat atgtctataa
     3961 agttggtctt gtatcaggag actattctta ctcaacagcg gttggtttgt ttaatgcagt
     4021 gattaacgta gtattgcttg ttgcagttaa ccaaatcgtt aaacgcatga ataatggtga
     4081 aggaatttaa ggaggaaagt atgaaaaatt cgattatgga tacaaaattt gatagacgta
     4141 tcttactctt aaataaaatc attattgtct ttatcgtttt gatgactttg cttcctttac
     4201 tttatatcgt cgtagcatcc tttatggatc ctaaggttct ggttagtaga gggattagct
     4261 ttaatccagc cgattggact gtagaaggtt accagcgtgt attcagtgac caatctattc
     4321 taagaggttt tatcaattct ctactatact cttttggatt tgcagcttta acagtattgc
     4381 tatctgtgtt tacagcttat cctctttcta agaaagactt ggttggacgt cgttggatta
     4441 actacttctt gattgtgact atgttctttg gtggtggttt agtcccaact tacttgctcg
     4501 taaaagaatt gggaatgctc aatactccat gggctatcat tgttccaggt gctgtcaatg
     4561 tttggaatat tattcttgct agggcctatt tccaaggatt gcctgaagaa ttagttgaag
     4621 ctgctgtcat tgatggagcg aatgacttgc agattttctt taaaatcatg cttcctcttg
     4681 caaaaccaat tatgtttgtt ctcttcctct atgcttttgt aggacagtgg aactcatact
     4741 ttgatgcaat gatttatatc aaggatccaa acttggaacc attgcaactt gtacttcgta
     4801 aaattctcat tcagagccaa ccaggtcaag acatgattgg agcacaagcg gctatgaatg
     4861 aaatgaaacg tttagctgaa ttgattaaat acgcaactat tgtcatttcc agcttgccat
     4921 tgattgttat gtatccattc ttccaaaaat actttgataa aggaattatg gctggttcac
     4981 ttaaaggata aaaaaagaaa aaataaaagg agttttctca tgaaattcaa aacattctca
     5041 aaatcagcag ttttgttgac agctagttta gcagtacttg cagcctgtgg ctcaaaaaat
     5101 acagcttcaa gtccagatta taagttggaa ggtgtaacat tcccgcttca agaaaagaaa
     5161 acattgaagt ttatgacagc cagttcaccg ttatctccta aagacccaaa tgaaaagtta
     5221 attttgcaac gtttggagaa ggaaactggc gttcatattg actggaccaa ctaccaatcc
     5281 gactttgcag aaaaacgtaa cttggatatt tctagtggtg atttaccaga tgctatccac
     5341 aacgacggag cttcagatgt ggacttgatg aactgggcta aaaaaggtgt tattattcca
     5401 gttgaagatt tgattgataa atacatgcca aatcttaaga aaattttgga tgagaaacca
     5461 gagtacaagg ccttgatgac agcacctgat gggcacattt actcattccc atggattgaa
     5521 gagcttggag atggtaaaga gtctattcac agcgtcaacg atatggcttg gattaacaaa
     5581 gattggctta agaaacttgg tcttgaaatg ccaaaaacta ctgatgattt gattaaagtc
     5641 ctagaagctt tcaaaaacgg ggatccaaat ggaaatggag aggctgatga aattccattt
     5701 tcatttatta gtggtaacgg aaacgaagat tttaaattcc tatttgctgc atttggtata
     5761 ggggataacg atgatcattt agtagtagga aatgatggca aagttgactt cacagcagat
     5821 aacgataact ataaagaagg tgtcaaattt atccgtcaat tgcaagaaaa aggcctgatt
     5881 gataaagaag ctttcgaaca tgattggaat agttacattg ctaaaggtca tgatcagaaa
     5941 tttggtgttt actttacatg ggataagaat aatgttactg gaagtaacga aagttatgat
     6001 gttttaccag tacttgctgg accaagtggt caaaaacacg tagctcgtac aaacggtatg
     6061 ggatttgcac gtgacaagat ggttattacc agtgtaaaca aaaacctaga attgacagct
     6121 aaatggattg atgcacaata cgctccactc caatctgtgc aaaataactg gggaacttac
     6181 ggagatgaca aacaacaaaa catctttgaa ttggatcaag cgtcaaatag tctaaaacac
     6241 ttaccactaa acggaactgc accagcagaa cttcgtcaaa agactgaagt aggaggacca
     6301 ctagctatcc tagattcata ctatggtaaa gtaacaacca tgcctgatga tgccaaatgg
     6361 cgtttggatc ttatcaaaga atattatgtt ccttacatga gcaatgacaa taactatcca
     6421 agagtcttta tgacacagga agatttggac aaaattgccc atatcgaagc agatatgaat
     6481 gactatatct accgtaaacg tgctgaatgg attgtaaatg gcaatattga tactgagtgg
     6541 gatgattaca agaaagaact tgaaaaatac ggactttctg attacctcgc tattaaacaa
     6601 aaatactacg accaatacca agcaaacaaa aactagaggt tgattatggg agataagaaa
     6661 tacacagtag aaaaagccaa tcgttttata gcagaaaata aacatctcgt taatactcaa
     6721 tataagcctg aagaacattt ttcagctgag attggttgga tcaatgatcc aaatggattt
     6781 gtctattttc gtggagaata ccatctcttt tatcaattct atccatatga tagtgtttgg
     6841 gggcctatgc actggggaca tgctaaaagt aaggacttgg tgacttggga gcacttgcca
     6901 gtggcacttg ctcctgacca agattatgac cgaaatggtt gtttctcagg ctctgccatt
     6961 gtcaaggatg atcgcctctg gctcatgtac actggacata tcgaagaaga aaccggtgtc
     7021 cgccaagtgc aaaatatggc attttcagat gacgggattc actttgaaaa gatttcccaa
     7081 aatccagttg caactggatc agacttgcca gatgagttga ttgctgctga tttccgtgat
     7141 ccaaaactct ttgaaaaaga tggacgctat tactccgtag tagctgccaa acataaggat
     7201 aatgtgggct gtatcgttct actagggtcc gataacctag tagaatggca gttcgaatcc
     7261 atctttttaa aaggggtaga acaccaaggc tttatgtggg aatgcccaga ttacttcgag
     7321 ttagatggga aagattgcct tattatgtca cccatgcgtt atcagcgtga gggagactca
     7381 tatcataaca tcaactcatc gcttttgttc acgggtaagg tagattgggg agaaaaatgt
     7441 tttatcccag aatcagttca agaaattgat catggccaag acttctatgc gcctcaaaca
     7501 ttgttggacg atcaaaatcg tcgtatcctg attgcttgga tgcagacatg ggggcgtacc
     7561 cttccaaccc atgaccaaga acacaaatgg gcatgtgcca tgactttacc tagaatttta
     7621 agattggaag atggcaaact aagacaattc cctgttaaaa aaggccaata tcaaatccaa
     7681 atagataaag attgtcatta ccacttagga aatgatatag attatcttga atttggttat
     7741 gatagtaatg cgcagcaagt ttacattgat cgtagccatc ttattcaaaa aattctaggt
     7801 gaagaagaac aggacactag tcgacggtat gtagatattg aagctaaaga attggaagtt
     7861 gttctagata aaaattccat cgagattttt gtcaatcaag gtgaagcaag cttgactgca
     7921 acttattact taacggtgcc agctgagcta tcacgaattg attaaaaatt aagttatttc
     7981 tcctaaagaa aaagttctct ttctaaaata gtggaaagag gactttttgt gttttgggta
     8041 tataagctta gtttatggta tttgtaaaat tggtgttgga ttatgattta agctagtttt
     8101 ctaaagaatt tgaaaaaaat tttatttaag caaaaaaaaa cccttggttc caaggctttt
     8161 cctgttgtat ttatatgccc cctacaggga tcgaacctgt gacccacgga ttaagagtcc
     8221 gctgctctgc cagctgagct aaggaggcaa agaaaaaagc tgtattggtg ccgaaacttc
     8281 acggtttgta ttgaacccgc gcaattaagc aggtgggcaa ctcgctctaa ctgaagctgt
     8341 ttccgtgtga gacggcctac atgctgttag aagacttttg tttccctaat aatacaaaaa
     8401 atagtcggtc aacacttaag tgtgaagtcg tacaccacag cgtttctata cttatatgat
     8461 accacttttt caaaaaaaat caagaggaaa gtgcaatttt ttgaaaagga tttcagattt
     8521 ttcgcaaacg gtcgatagct tcctttcttt gagccaaagc ccgttcatat ttaccagtat
     8581 cttctgcttg gaaatagtga tgattacgaa ttttttctgg cagatagtct tgcttgaccc
     8641 aatttccagg atagttgtgt ggatagagat agtcttgggc attccccagt tccttgcttc
     8701 cactgtagtg cccatcacgt aggtgtcgcg gaataggcaa gtgccctgat gttttgaggt
     8761 cagcaagtgc cttatccata gctacatagg ctgagttgga ttttggagaa agggccaaat
     8821 caatcacgac attggcaatg agaatgcggg cttctgggaa cccaatcttc tgggcagcat
     8881 ccagagcagt cacggtatga atctgggcct caggattggc taagccgata tcttcatagg
     8941 cgataacagt caagcgacga gcgagactag gcagatcccc agcctcaatc aagcgggcag
     9001 tatagtggag actggcatcc acatctgagc cacgaataga cttttgcagg gcagatagaa
     9061 catcatagtg accgtctcca tccttgtcca tagtgatgta gcttctctga agactatttt
     9121 ccatgatgtc taaggtgatg tggcgaatgc cctcgtcatt ctcaggggta gagagaacag
     9181 ctaagtccag tgagttaaag gcagagcgaa ggtctccgtt tgtagaggtt gcgatgaaat
     9241 ccagcgcatc ctcatctagt tctattggaa aatcaaaacc acgttcaggg ttacttagag
     9301 ctatctgcag ggcctctttg acgtcttggt tagacagagg ttccaactcg aaaatttgaa
     9361 ctcggctacg aatggcagga gtgacagaga agaaaggatt ttcagtcgtt gctccaatca
     9421 tgatgaccag tccactttcc aagagaggca agaggaagtc ttgcttggtc ttatctagtc
     9481 gatgaatttc gtctagcaat aggacgagac caccagaaaa tttagcttct tccgagattt
     9541 cttgcagtcg ctttttacta tcaactgtcg cattgaaagt tcgaaaggca tacttggtcg
     9601 ttccagcgat ggcagaggca atactggttt tgccgattcc aggagggcca tatagaatca
     9661 tggaggacag gcggttggct tccaccatgc ggcggatgat ttttccaggt ccgaccagat
     9721 gctcctgacc gatgacctgg tcgatggttt tagggcgcat gcgaagcgcg agattgtctg
     9781 gcatagcagt cctttctagc gtggatttga gtagaatgac tcatctacta tatcttacta
     9841 tgtccattct agcctattag ttgtgatatt tcaatggttt tgtaataatc agggagtgag
     9901 atagaatctt ttttactatt taatttaatg aggagaggta tcagcatgag agatttgatt
     9961 ttccttaaag ctcaaaatag gatagttgag cctaaagaag tggaagtgct gacttgagaa
    10021 ataatattgc tgaatgtcat tgtatgaact ataatgaaaa gagaggtgat aagtaatgga
    10081 aatgatggac caagtcagga aattttgatt tttacaaaac aaattcgtca ttggattctt
    10141 agtgatcaag ttatttcagg gaaaagaaaa cttttcttcc gggaagatac tccaaaagag
    10201 attttagatt tgtacgaaaa cattaaatct aaacttgatt ttgcttacca ataagtttat
    10261 tctaataatg ggttgaaaaa atatgaaaaa tagaataatt gatgtttttg aagtagtaaa
    10321 tcgcatcctt gtaataactg ttgaaaatcc tgatttcgaa gacttgagag ttaatcatac
    10381 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggtaa
    10441 ggcgacgttg acgtggtttg aatttgattt tcgaagagta tcagtttgta aaaattggag
    10501 ataaaaaata tagagtacgc agtgttccta tgattcattc aactccgcct caatctgtct
    10561 tagatcgaga tacttttaca attgactata cagatgatga attgctcgat aaagaagcag
    10621 tttttactac tcattagaaa aataggtctg aataaattgg cttcccttag aaccacatct
    10681 aggggctttt atgtataata gaataataag tatcactcct ttacaatacg tgtaacacgt
    10741 gttataatgg tgttgtcagg aggtaaaagc gctatgccta tgacacaaaa agagatggtt
    10801 aaactcctta cggcccatgg ttggataaag actagaggcg gtaaaggctc ccatattaaa
    10861 atggagaagc aaggggaaag acttatcaca atccctcatg gtgagctgaa taagtacact
    10921 gaaagaggga taagaaagca agctgggttg taaaattcag cccctgtttt ttgatatgga
    10981 ggtagtgaaa tgttagttac gtatccagct ttattttatt atgacgacac agacggaaca
    11041 gaagcgactt attttgtcca tttcccagat tttgaatact cagctacaca aggagagggg
    11101 atttctgagg ctttggctat ggggtcggag tggctaggga taactgttgc agatttgata
    11161 gagagtgatg gagagttacc tcagccatca gatatcaata gcttgtcttt aattgataat
    11221 gatcctttta aagatgatga agatttcgtg tcaacctatg accttgataa atcttttatt
    11281 tctatggtat ctgttgatgt atcagaatac ctaggaagtc aggaacccat aaaaaagact
    11341 ttgaccatac caaaatgggc agataagttg ggacgagaaa tgggacttaa cttttctcag
    11401 actttgacag acgctattgc agataagaaa gttcaagcct aagattaagc gtggtatcgt
    11461 ggtaatagtc aataaaaaag cacgtccact tgtgctagtt actcgcctat tgattttata
    11521 gatttattag ccctttcgcg ggctttttat attgattttt atgagaaatg aagaaatcag
    11581 acttttaaga aaatcactga taccaagggt ttaaatgagg taatatggta taattaggac
    11641 ataaaataat tttgtggtaa gatggtagta tctattttag catatttccg agcaatcggg
    11701 gcgattaaag agtcgcatag aaagaggaca aaatggcaac atacggattt ttagatgttt
    11761 tagaggaaga gttggacaag aactttccct ttgactttga gattagctgg gacaaacgca
    11821 accatgcggt agaagtgagt tttctattgg aagcgcaaaa tgctgcaggt gtggagatgg
    11881 tggatgaaga cggagaggtt ttatcagatg acattctttt tgaggaagcg gtccttttct
    11941 acaatcctgc caagtcaaca gtcaatgagg aagactattt gactgttatt ccttacctgc
    12001 ctaaaaaagg attttcccgt gaatttttag cttattttgc gcttttcctt aaagatactg
    12061 ctgaggttgg gctagatgtc ctcatggact ttttggaaga cccagaagca gaggaatttg
    12121 tcatggaatg gaaccaagaa gtctttgaag aaggaaaagt tggcttggaa gagggagaat
    12181 tttatcctta tccaagatac taggagttgg ttggaggtgt tatgaagaaa attgggactt
    12241 atttggttta tgtgctagct tttgtcttta ttatgctagc ttttgcttgt ggaacaatcg
    12301 catttgcaga gttggggtat tccgcagttt tagcctttac ttttggttat gccttcgctc
    12361 ttctaagcat gtatttaatc tttattcttc atgagctggg tcatgctttt tgtggctact
    12421 tgacaggcta tcggctggtg gcttttggat taggacattt tattttgacc aaaaagtcag
    12481 gcaggtttca tcttagtaga acagccattc tgaaaaatgt tggtgctcaa tacattggtt
    12541 taaaagagga tgaaagcgat caaagaatca tcctgatgct ttcaggaggc ttgatggttc
    12601 atctcggctt gatattattg gcgatagtgt ttggattttt gacaagaagc tggtattttg
    12661 cagggacttg gatttttctt aatttatctt tcttcctaaa taacattttg ccagtcgaca
    12721 tcaccgatgg agcaaaaatt tgggaattac tacaacaccc tgaaaatacc aaatacgcct
    12781 acctggtatt gagacattct gctcaaactt tgctggctcc tcaagaatat gatttgaaag
    12841 actttgttca agcagttcct gaggatgcac gagggagttt tgcggatggt gtattaggta
    12901 tgcaaggtga agtttccatt ttggaaggga aggaagaagt agctaaacag cagtttcaag
    12961 cattacttga gaggacaact actccgatga tgcagacagt tgcccaacta tccctgcttc
    13021 atatcgcctt gttggaagga gattttgagc aagcggagca atatgctagt attcgacagg
    13081 tcaaatcgtt tctgtctctc aaactgtcca atcttcaagt gatacaagct tggtatcaat
    13141 ttaaggtaaa gaaagatgta gatcgaactc gtaaggctct caagattgct agacagaaaa
    13201 tggatagtag tcgaatgttg agggacgaga aacgctatta tgaaaacttg ttagcagagc
    13261 tggaaaagga aatgttagaa ggaactgaag atggaactag aaatttctga tttcccaggc
    13321 tgtaagattg ctttgttttg tggggataag ctcttgacta tcttacgtga tgataaggca
    13381 agtattccct gggccaatat gtgggaactg ccaggtggtg gaaagagtgt cagggaaaat
    13441 ctgatatagt tttgtattaa aagaatatcc tttcaaggtt attctttttt aattttgtcc
    13501 caaaataatt gactttgtcc cgaaaatata gtattatttg tgtaaggagg aatgaatcat
    13561 gaaaaaatca gatgttcttg atttaataaa gtatcattat gagggcagag agacagaatt
    13621 tagaaatcaa tccatagcaa ttgctcggaa cttcaataaa catggtgata cacaaatagc
    13681 acaatatatt atggggttaa tgtctcaaag tgatagattc atgccacaaa tagaaaatcc
    13741 tagtgagtat ttgactcctg ctaaactaga tattggtcct ctcccattgc ctctttcaat
    13801 tatgaatgat ttaaaaggaa taataaacgc tgtcaatcat catattggaa taaataaatt
    13861 tttatttgtg ggatctccag gtactggaaa aactgaaagt gtaaagcagg tggctagact
    13921 tattggcaag gaattacttg tagtagattt cagtcactta gtagatagta agctagggca
    13981 aacagtcaaa aacttagcaa ctctttttaa tgaaatcaat aatcttcctt tcaagcaaaa
    14041 ttatatcatc ctatttgatg aaattgattc catagtgttg gatagggtta atcagaatga
    14101 tttaagagaa atgggacgag tgacttctgc ctttttaaag gagttggata ggctgtcacc
    14161 agaaattgta ttaattgcaa caacaaatct ttttgaaaat cttgataaag cagttacgag
    14221 aagattcgat gccataattg actttgaccg ttatactgat gaagataaag tagaagtagc
    14281 tactattatt ttaaatgagt tattaaagca atttaagaat gtagctagag atttaaaatt
    14341 atttaaaaaa attatcaata gtgccaatgt aataccgaat cctggtgatt tgagaaactc
    14401 aataagaacg tcattggcat ttagtgaccc atcagatccg catgattacc aaaaacgcct
    14461 gctaagaagt ttgcataatg gtagaaattt atctatttct aaattatcga agctaggttt
    14521 tactgttaga gaaattgaga ttttgacagg tatttctaag agtagtgtat cacgagagtt
    14581 aagcgaggat taaaatgaat acattattga cattacgagg taaaagtttt acacaaaaat
    14641 caagaaataa tggtatggga ccaataacta tacccaaaaa aacaataatt acattggaac
    14701 atttgaagta tcttcatttt tcattagaag agacgaaaac atattgggag aaaaataaca
    14761 ttatcgatgg tattttgatc agtatttact ataatcgaat tgttgccaaa agtaaccgta
    14821 ttaatggcta tttcaatgta ggaggaggga atccattccc taatgatact attgtgggag
    14881 caaaattcaa tgatgagaag acaaaacata ttgttactca ttatatttct agagatgctc
    14941 ttaataaaac aataaccgtt ttaagtaaga taattgaagt ttttgaggaa cattttgata
    15001 gagcgataac atgtgagatg ttttctgatt catcaacgtt tgcttctata aatttttcgg
    15061 agtatggtat ttcaaaaagc aaatttcaac agtatttgag agattcttgc tttattgaga
    15121 attttggagt tgagcacact actgtttctg atattcaaaa ttctatcgtg acattttatg
    15181 atgtccatac agacattttt agattactga ataaattaaa tattgatatt tcagaagcta
    15241 atatcatgaa tcagaccacg gtcttgcttg atgaaaaaaa tattgaattg ctactatcaa
    15301 aagcgcccta tcttgtctcc atgattgtgg aagatttttc taagttatct gtagatgatt
    15361 tttctttaga taataatgat ttaaaaataa atcttccatc tccaatgaac gaaccagttg
    15421 ttggcgttat tgatacctta tttgacaaaa gagtttactt taatgagtgg gtagaatatc
    15481 atgattttgt ctcacctgat attagcaaag atagccaaga ttacaagcat gggacagctg
    15541 tgacttcttt aatcgttgat ggagccaatt tgaaccctaa tctggatgat ggttgtggaa
    15601 attttagagt gaggcatttt ggtgtgtcac tacaaagtgg atttaattca tttacaatca
    15661 taaaacagat aaaagagatt gtttctcaga atgctgatat taaggtttgg aatctttctt
    15721 tagggtccaa tgatgaaata agagaaaatt ttatctctgc agagggagca ttattagacg
    15781 aaattcaatt tgagaatgat gtaattttta tcatagctgg gacaaatgct tcagtaataa
    15841 atgggaaacg caaaagaata ggtgctcctg ctgattcact taattctata atagtaaatt
    15901 ctgttgattt taataatcaa tcagtgtcat attcacgaga gggtattgtt ttatcattct
    15961 ttgttaaacc agatgtgtca tattatggag gaggaaatgg tgactttata aatgtttgtg
    16021 aacctctagg attaggtcgt gtagctggaa caagttttgc ggcacctttt attgcaagga
    16081 aaatggccta tctcattcat attatgggac ttagccgaga agaagcgaag gctttgctaa
    16141 ttgatgcagc aataccctgg aatgataaga aaacattcac tgatttatct ttgataggaa
    16201 atggtattgt tccaataaaa atggatgata ttttatctac acctgatgat gaaattaaat
    16261 ttattgtgtc agatatctct agggcttatg atacctataa ttatgatttt ccagtaccta
    16321 tttctagtga gagttatcca tatgtagcta aagcaacaat gtgttatttc cctaactgct
    16381 caagaaaaca aggggttgat tatacaaata ctgagatgca gcttactttt ggtaggttaa
    16441 agtcagacgg tatcaaatcg ataaataaag acaaccagca tgccgaagat accccaggat
    16501 atgtgagaga aaacgctgct agaaatatat ttaggaaatg ggataatgtc aagcatattg
    16561 gagagtcgtt tacttctcga aagagagcta aagcaatttt aaatccatct aatcctcagt
    16621 gggggatgag tattaaaaca atcgaacgtt tgaaaagcgg tgatggacaa ggagtacgtt
    16681 ttggtgtagt agttacatta aaagaattaa atggggttaa tcgtattgaa gattttattc
    16741 agcaagctga attacgcggt tggctagtta atagattgca agtagaagct caagtagacc
    16801 tctttaatag tttaaatgaa gaaattgaat ttgaatagtg gatattttat ccttatttta
    16861 gatcttagga acacaagagg gcaaagatat gaatattact tatatagttg gaaatggttt
    16921 ggatttgcaa tatggtttga aaacaagata tagggatttc tacgaattcc aaaataaggt
    16981 ttatataagt aggacagaga acgaggaaaa atattcaaat ttcatttatg agtctctatt
    17041 ttctgataaa gtaaatgatt atgaaaattg gtcagatttt gaattgtcaa ttggtaaatt
    17101 gacaaaagat aacgacctca tctcctcaag tatagaaata aaggagaaat ttatagatga
    17161 ttttagtgaa gtagttgatg atttaagaga atatctacgc atacaacaag aaaaaaatct
    17221 tgagaaaggt aatgcaattg actttataag cactctagat gatatgagga cctctctccc
    17281 tgtaattaat caacctgcta tcgataaaaa atacaatgag aatccacatc aggacgacat
    17341 tgtaaatata gtaacactta attatacaca tgtaatcgat aaattatata atgggtcagc
    17401 aaaatcattc aggaatcaat tacgagctaa tctttataat ttttatattg agccaccaat
    17461 tcatgcacat gggacggtgg atgtctgcac ggttttaggg gttagtgatg aaatacaaat
    17521 ttcaaatagt ttagaagaac aaaaggaatc cctaataaaa agtttagttt taaaaaacta
    17581 tagagaaaat atggatgtaa agaatagtga tattataaaa aattctgaca tcattattct
    17641 ctatggggtt tctttgggag aaactgatag gtatatctgg agtcagattg ctgaacgatc
    17701 aatcagcggt tctgttcctg tcataattta ccactatgta cctcattttg atccggggaa
    17761 tcccattaga gcaaaacgcc tatatagaaa tgtagaagat aaattcatac agaatagtgg
    17821 tatagactta gagttagaga aaaaattaag agacaacctt attgtcgtta ttggtaagac
    17881 tatttttgat ctaatagaga ggtaatttta aaaaacaaaa tggaaacatg gcaagagtta
    17941 aaagttacag tgaagcgtga gggagaggag ttggtttcca atctcttgat tgagctggga
    18001 gcgcaaggtg ttgcgattga agacagtatg gactatgtgg gaaatgttga ccgctttggc
    18061 gagattttcc cagaggtgga gcagcaagaa gaaatcgtag tgacagccta ctaccctgac
    18121 acggtggatg tgacagtggt tgaggcggac ttgcaggctc gcttagcaga attgacggat
    18181 tttatggatt tgggagagtt aaaaataggt acgactgtct tggctgagga agactgggca
    18241 gataactgga agaaatacta tgagccagct cgtatcactc atgatttgac catcgttccc
    18301 tcttggacag actatgaggc gactgcgggg gaaatgatta tcaagctgga tcctggcatg
    18361 gcttttggta ctggaaccca cccaactacc aagatgagcc tttttgcctt ggaacaggtt
    18421 cttcgtggtg gcgaaacggt gctagatgtg gggactggtt caggggttct ctctattgcc
    18481 agctcgcttc tgggggctaa agaaattttc gcctatgacc tagatgatgt agcagttcgt
    18541 gttgctcagg aaaatattga acttaaccct ggaatggaaa atatccacgt tgctgctgga
    18601 gacttgctta agggtgttga gattgaggca gatgtgattg tagctaatat cttggcggat
    18661 attctcattc atctgacaga cgatgcctat cgtttggtca aggatgaagg ctacctgatc
    18721 atgagtggca ttatcaagga caagtgggac atggtgcgcg agtcggctga gtcagctgga
    18781 tttttccttg aaacccacat ggttcaaggg gaatggaatg cctgtgtctt taagaaaacc
    18841 aaggatattt ctggtgtgat tggaggctag catgcagcag tattttgtaa aaggcagtgc
    18901 tatctctcct gtcactatcg aggacaagga aaccagtaag catatgtttc aggttatgcg
    18961 cttgaaagaa gaggatgagg ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg
    19021 cgtgctggat atggaaaatc gtcagtttga gttggtccaa gaattaaatg acaatgtgga
    19081 actaccagtt caagtgacca tcgcatctgg atttcccaag ggagacaagc tggagttcat
    19141 cgctcaaaaa gtaaccgaac tgggtgctag ccaaatctgg gcctttcctg cagactggtc
    19201 agttgccaag tgggatggca agaaattggg taaaaaagtt gaaaaactag aaaaaattgc
    19261 ccttggagca gccgagcaaa gcaagcgtaa tattgtacca agtattaaac ttttcgagaa
    19321 aaaagcagat tttctaactc agctggacca gtttgactct atcatagtag cctatgaaga
    19381 atcagctaaa gaaggagaag ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg
    19441 agccaaactg ctctttatct ttggtccaga aggcggtctc tcacctgcag aaatcgaaag
    19501 ttttgaagct aagggagccg ttttggtagg cctaggtcct cgtattttgc gagcagaaac
    19561 agcaccgctt tacgccttat cagcccttag tgttttagta gaattagaga aataagagga
    19621 agaaaatgga acaaaaacac cgttcagaat ttccagagaa ggaactttgg gatttaacag
    19681 ctctatacca agaccgtgag gatttcttgc gtgcaatcga gaaagctcgc gaagacatca
    19741 accagtttag ccgtgattac aagggcaatc ttcacacttt tgaggatttc gagaaggcct
    19801 ttgcggaatt ggaacagatc tacattcaga tgagccatat tggcaactat gcttttatgc
    19861 ctcagacgac ggactatagc aatgacgaat ttgcaaatat tgctcaagct gggatggaat
    19921 ttgaaacaga tgccagcgta gccttgacct tctttgacga tgccttggtg gtagcagacg
    19981 aggaagtctt ggaccgtttg ggtgaattgc ctcacttgac ggcagctatt cgtcaggcca
    20041 aaatcaaaaa agcccactat ctaggggctg atgtggagaa ggccttgacc aatctcggtg
    20101 aagttttcta tagtccgcag gacatttata ctaagatgcg agctggggat tttgaaatgg
    20161 ctgactttga agcccatggc aagacctata aaaacagctt tgtcacctat gagaatttct
    20221 accaaaatca cgaggatgct gaggttcgtg agaaatcctt ccgttccttc tcagagggac
    20281 ttcgtaagca ccaaaatacg gctgcagcag cctatctggc tcaggtcaag tctgaaaaac
    20341 tcttggctga tatgaaggga tacgactctg tctttgatta tcttctagct gaacaagaag
    20401 tggaccgtgt catgtttgac cgccagattg acctcatcat gaaggacttt gcaccagtcg
    20461 ctcagagata cctcaagcat gttgccaagg taaatggtct tgaaaagatg acctttgcag
    20521 actggaaatt ggacttggac agcgccctca atcctgaagt gactattgac gatgcctatg
    20581 atttggtcat gaagtcggta gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt
    20641 accaagaaga gcgctgggtg gactttgctg ctaacagtgg caaggattcc ggtggttatg
    20701 cggcggaccc atatcgcgta cacccttatg tactcatgag ctggacaggc cgtttgagcg
    20761 atgtctatac cttgattcat gaaatcgggc attctggtca attcatcttt tcagacaatc
    20821 accaaagcta tttcaacgcc cacatgtcga cctattatgt tgaagcaccg tcgaccttca
    20881 atgaattgct actcagtgat tacttagaga accagtctaa tgacccacgt caaaaacgct
    20941 tcgctctggc tcatcgcttg acagacacct acttccataa tttcatcacc cacctcttgg
    21001 aagccgcctt ccagcgtaag gtgtatacat tgattgaaga aggagaaacc ttcggagcaa
    21061 gcaaactcaa cagcattatg aaggaagttt tgacagattt ttggggcgat gccattgaaa
    21121 tcgacgacga tgcagctttg acttggatgc gccaagctca ctactatatg ggcttgtata
    21181 gttacactta ctctgctggt cttgtcatct cgacagctgg ttaccttcat cttaaaaact
    21241 cagaaactgg agctgaagac tggctcaatc tcctcaaatc aggtggtagc aagacaccac
    21301 ttgagtcagc catgattatc ggtgctgata tttcaacaga caaaccactc cgtgatacca
    21361 tccaattctt gtctgacaca gttgaccaga ttatcgccta cagtgctgag ttgggggagt
    21421 aaggggaata gaaaaatttt ctagaatgat gtttatgggc ttgttaagcg tcattctatt
    21481 tgtcttagtt gtagctattt tcaaaaatgt cgttgaaggt cgtgatgtta aatttgaact
    21541 tactgtagaa ctggtattga tagttattta cgtcatttta tatcagattg tatttaattg
    21601 agaattcaat attgagtcat ttaagactgc ctttttgaac agttgctaga aatgtagagg
    21661 tattgaccat gtatcaagat ttactaagaa aaatagcaga agaaaaacca aattataacc
    21721 aggaagaaat ccagtggttg tttgatcatt tgggaaatcc ttctccagaa attcgtgatg
    21781 acctttcaaa tcaaggcttg cactatcttt caaaagaaaa ggatacaaca ggtttctcaa
    21841 gtcagtatgg ttgggttcac gcttttgcac atggagccga tttactgaca gaggtggttt
    21901 gtcatccaga ctttcctaaa aacagagttc atgaagtatt tgatatactt ggccaactat
    21961 ttaaaagaat gtcgattcgc tttacagatg atgaggattg gcgtttagca agagtgatct
    22021 atgaacctat tttacaaggg aagttggagc aagaacaagt agcttcttgg ataaaaactg
    22081 ttgattttcc gatagaagaa agggaggatt tttacaaatt ttccaacttt agatcctgtc
    22141 tggtggaagt ctatgtccaa cttgaccaga gaaatagttt acaagatgag ttgaaagaag
    22201 ctatccagtc ttttcaatac tagagattag ctaatagttc tatgattttc aaaaaatttc
    22261 caatcaattt tcttgaaacc ctttcctact tttgatagac tagtatctag tttttgaaaa
    22321 aaggagaaag aaaatgaaaa aatttgttgc tgagttaatc ggtacgttca tgcttgtgtt
    22381 cgttgggaca ggagctgttg tttttggaaa tggtcttgat ggccttggtc accttggaat
    22441 cgcctttgcc tttggtttgg caatcgtggt ggcagcctac tcaatcggaa ctgtttcagg
    22501 tgctcacttg aacccggctg tttcgattgc tatgtttgta aacaaacgtt tgtcatcttc
    22561 agaacttgta aactacatcc ttggtcaggt tgttggagct ttcatcgctt ctggcgctgt
    22621 cttcttcctc ttggctaact caggtatgtc aactgctagt cttggtgaaa atgccttggc
    22681 aaacggtgtc actgtctttg gtggtttctt gtttgaagtc atcgcaactt tcttgtttgt
    22741 attggttatc atgactgtga cttcagaaag caagggcaat ggcgcgattg ctggtttggt
    22801 aatcggtttg tcattgatgg cgatgattct tgtcggattg aagattactg gactttcagt
    22861 aaacccagct cgtagcttgg caccagctgt cttggtaggc ggcgcagccc ttcaacaagt
    22921 ttggattttc atccttgcac caatcgctgg tggagttctt gcagcccttg ttgcaaaaaa
    22981 tttccttgga acagaagaat aattgaaact caaaaagcct tgctcctcat cttgaggaac
    23041 agggcttttt cgtatgatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
    23101 cgtaggtatg gttactgact tcgtcagttc tatcc
//
LOCUS       DAVLHM010000035        22720 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLHM010000035 DAVLHM010000000
VERSION     DAVLHM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.035"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            169..822
                     /locus_tag="VXE45_001519"
     CDS             169..822
                     /locus_tag="VXE45_001519"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0789535.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            832..1296
                     /locus_tag="VXE45_001520"
     CDS             832..1296
                     /locus_tag="VXE45_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0789536.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1309..2577
                     /locus_tag="VXE45_001521"
     CDS             1309..2577
                     /locus_tag="VXE45_001521"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0789537.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2591..2851
                     /locus_tag="VXE45_001522"
     CDS             2591..2851
                     /locus_tag="VXE45_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789538.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2862..4223
                     /gene="pdrM"
                     /locus_tag="VXE45_001523"
     CDS             2862..4223
                     /gene="pdrM"
                     /locus_tag="VXE45_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0789539.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4377..5345
                     /locus_tag="VXE45_001524"
     CDS             4377..5345
                     /locus_tag="VXE45_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0789540.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5361..6353
                     /locus_tag="VXE45_001525"
     CDS             5361..6353
                     /locus_tag="VXE45_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0789541.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6571..7614
                     /locus_tag="VXE45_001526"
     CDS             6571..7614
                     /locus_tag="VXE45_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0789542.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7678..9363
                     /gene="lpdA"
                     /locus_tag="VXE45_001527"
     CDS             7678..9363
                     /gene="lpdA"
                     /locus_tag="VXE45_001527"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0789543.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9427..10416
                     /locus_tag="VXE45_001528"
     CDS             9427..10416
                     /locus_tag="VXE45_001528"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0789544.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10489..11559)
                     /gene="xerS"
                     /locus_tag="VXE45_001529"
     CDS             complement(10489..11559)
                     /gene="xerS"
                     /locus_tag="VXE45_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0789545.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12067..13617)
                     /locus_tag="VXE45_001530"
     CDS             complement(12067..13617)
                     /locus_tag="VXE45_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0789546.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13633..14412)
                     /locus_tag="VXE45_001531"
     CDS             complement(13633..14412)
                     /locus_tag="VXE45_001531"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0789547.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLSISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKEN"
     gene            complement(14399..15250)
                     /gene="ylqF"
                     /locus_tag="VXE45_001532"
     CDS             complement(14399..15250)
                     /gene="ylqF"
                     /locus_tag="VXE45_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0789548.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWCQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15496..20745)
                     /locus_tag="VXE45_001533"
     CDS             complement(15496..20745)
                     /locus_tag="VXE45_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0789549.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVIGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVQPALPEAVVTDKGEPEVQPTLPEAVVTDKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVKEVGEDGERQIVT
                     SYEELHGKKISEPVETVTILKEMKPKILVKGTKENPKEKTVPVLTLTKVTEDAMNRSA
                     NLNYELDNKDNAEISSIIAEIKDGDTVVKKVDLSKEKLTDAVQNLDLFKDYKIATTMI
                     YDRGQGSETSKLDEKTLRLELKKVEIKNISSTNLVKVNDDGTEIPSDFMSEKPSDEDV
                     KKMYLKITSRDNKVTRLAVDKIELVTEKEKELYKITASAQDLIQHVDPSKTRNEYIHY
                     IEKPVPKVNNVYYNFNELVRDMQEHPNDEFKLGADLNATNVSAFGKSYVTKDFKGKLL
                     SDGDNHYTIHNLSRPLFGNVIGGTIKNINLGNVDINMPWANQVAAVANIIKGGTTIEN
                     VKVKGNIVGKDWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVE
                     RAYVNANLIGKKAKAAGIAYWTQNEGNNNTVRQEGAIKKSIAKGTIQVTEAIESGGVV
                     GSMKHHGSVEDSVSMMKVPNGEIFYGSSDIDYDDGYWTGDNVRRNYVVIGVSDGHSSY
                     QRSKDKNRIRPISEEEAKSKIEATGITADKYEINEPVVNRLNRLTRREDEYKSTQDYK
                     VDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDI
                     DHVMIHYADKTKEIKAVHQKESKVAQVREYSIDGLDDIVYTPNMVDKNRDQLIKDIKD
                     RLATVELISPEVRALMDKRDTSRDPNANSDERKNGYIRDLYFEESFSETKANLDKLVK
                     SLIENADHQLNSDEAAMKALVKKVDENKAKIVMALTYLNRYYDIKYGDMTIKNLMMFK
                     PDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFT
                     NDTDLNDWFIHAAKNVYIVEPKTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAH
                     MFLISTYNTMAYSSFEKYGKYTEAEREAFKDKIKEVAHAQQTYLDFWSRLALPSVRDQ
                     LLKSQNRVPTPVWDNQNYHNVEGVNRMGYDKNNKPIAPIRELYGPTWRYHTTNWYMGA
                     MASIFQDPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAY
                     AQGMLQTPDKSGNGEYGALGLNMAYHRENDGDQWYNYDPDKLKTREDIDRYMRNYNDA
                     LMMLDHLEADAVIPKLHGNISRWFKKMDRQYRKNGELHQFDKVRELTEDEKKKIVINN
                     IDDLVNNNLMTKHGAPSDRTYNPEDFDSAYVNINIMTGIYGGNTSQGAPGAASFKHNT
                     FRMWGYFGYENGFISYASSKYQGEADKTNKKLLGDDFIIKKVSKDKFNNLEEWKKQYF
                     KDVKSKAEKGFTAIEIDGRQITNYAQLKTLFAEAVQKDIDGMSDPKIKDHFKNTVDLK
                     SKVFKALLKNTDGFFNKLFKEDI"
     gene            complement(20789..>22720)
                     /locus_tag="VXE45_001534"
     CDS             complement(20789..>22720)
                     /locus_tag="VXE45_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0789550.1"
                     /translation="LERWYNFNYGETNAKDLIMYHLDFFGKSNSSALDNVIELGKSGF
                     NNLLAKNNVITYNVLLAKNYGTESLFKALEGYRKVFLPTISNNEWFKKQTKAYIVEEK
                     STIEEGREKQGKEGTKYSIGVYDRLTNPSWKYQSMVLPLLTLPEEKTVFMIANISTIG
                     FGAYDRYRSSEYPKGEKLNKFVEDNAKEAAKRFRDHYDYWYKILDNDNKEKLYRSILV
                     YDAFKFGTDKDKDKVTHQATFETDHPAIKYFFGPAGNNVVHNGHGAYATGDAFYYMAY
                     RMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLGPEFYAKGLLQAPDHPYDPTITIN
                     SVLKYEDSENSTRLQVADPTQRFNSAEDLHNYMHNMFDVIYMLEYLEGKAVANLETNQ
                     KYELLRKIENKFDLDQDGNNVYATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQ
                     EYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYE
                     KDAKAAGSKINSYGKEVGLVTDELVLEKVFNGQYKTWTQFKKDMYKEREKQFSKLNRV
                     NFINPNNPLSRQRNVSVTDIGVLERMIVEAVRDDAQDDVAKFYPETNSRVLKLKKAIY
                     KAYLDQTNDFRSSIFENKK"
BASE COUNT         6696 a         4414 c         4370 g         7240 t
ORIGIN      
        1 taatgattta aaaagtaatt ataaaaaata gccagtcttt ataaactgta ttcacgtatt
       61 caaatcgtat atatagtcga tttattaaat ctttagataa actgtaaaaa gtggtttcca
      121 tagccacttt ttgctataat agaggcagta aaaatgaagg agtcggctat ggaacactcg
      181 tcttggcatg ctttgattaa ggcgcaatta cctgagggtt atttcgggaa aatcaatcag
      241 tttatggagc aggtctattc tcaggggatt atttatccac ccaaggaaaa ggtttttcag
      301 gctctcttga caacactgct tgaagaagtt aaggtggtaa ttctagggca agacccctat
      361 cacggaccag gtcaagcgca gggcttgagt ttttctgtac ctgactctat cccagctcca
      421 ccatccttgc aaaatatctt gaaagaattg tcagatgata tcggagttaa gaaatctcat
      481 gatttgacag cttgggctga gcaaggagtc ttgcttctta atgcttgttt gactgttcct
      541 gctggacagg ccaatggtca tgctggtcaa atctgggagc cttttactga tgctgtgatt
      601 caggtggtca atcatctaga tagaccagtc gtttttgtac tctggggagc ttatgcacgt
      661 aagaagaagg cattagttac caatcctcat cacttgatta tcgaatcagc ccatccaagt
      721 cctttgtcgg tttatagagg attttggggt tccaagccct tttccaaggc caatgcattc
      781 ttaaaagaga caggacaaga gccaatcgat tggcttagat aaggagaaaa tatgcctcag
      841 ttagcgacga tttgctacat tgataatggg aaagaactgc tcatgctcca tcgtaataag
      901 aaacccaatg atgtccatga agggaaatgg attggtgtgg gtggtaagct agagagagga
      961 gagacgcccc aggaatgcgc ggcgcgtgaa atccttgaag aaacagggct caaagccaag
     1021 ccagttctaa aaggtgtcat cacttttcct gaatttacac cagatttaga ctggtacacc
     1081 tatgttttta aggtgacgga gtttgagggc gacttgattg actgcaatga ggggacgcta
     1141 gaatgggttc cctatgatga ggttttgagc aagccgactt gggaaggtga ccacaccttt
     1201 gttgagtggc ttttagagga taaacccttc ttttcagcca agtttgttta tgatggggat
     1261 aaattgttgg atacccaagt tgatttctat gaataaagga gaaagcagat gctactaatc
     1321 aaaaatggtc gtgtaatgga tcccaagtct ggtttggatc aagtttgtga tgtcttagtt
     1381 caagatggga aaattatcaa aattgcgtct gagatcacgg aagaaggagc agaaacgatt
     1441 gatgctactg gtcttgtggt tgctcctggc ttggtcgata ttcatgttca tttccgtgaa
     1501 cctggtcaaa cacataaaga agacattcat actggtgccc tagcagccgc tgcaggtggt
     1561 tttactactg tcgtcatgat ggctaatacc agtccaacca tttcagacgt ggagactttg
     1621 caagcagttc tccagtcagc tgccaaagag aagattaatg tcaagacagt tgcgaccatt
     1681 actaaaaact ttaatggtaa aaacttgact gactttaagg cactcttaga agctggtgcg
     1741 gttggtttct ctgatgacgg tattccgctt gagagcagta agattgtcaa ggaagccatg
     1801 gaggaagcca aaaaactcaa tacctttatc agccttcatg aggaagatcc aggtttgaac
     1861 ggtgttcttg gctttaatga aaatattgct agagaacatt tccatatctg cggtgctact
     1921 ggggtggctg agtacgctat gatggcgcgt gatgtcatga ttgcctatgc aactaaagcc
     1981 catgttcaca tccagcattt gtctaaggaa gaaagtgtta aagtagtgga gtttgctcag
     2041 gggttaggtg cagaagtcac agcagaagta gcgccacagc atttctctaa gacagaagca
     2101 cttcttttaa cacaaggtag caatgctaag atgaatccac cgcttcgttt ggaatcagac
     2161 cgtcgtgccg ttatcgaagg tctcaaatca ggtgtcatca cagttattgc gactgaccac
     2221 gcgcctcatc atgtagatga aaaaaatgtt gaggatatta ccaaagcgcc atctggtatg
     2281 actggcttag aaacatccct gtctctcagc ttgacctatt tagtagaagc tggtgagttg
     2341 agcttgatgg aattacttga aaaaatgaca tacaacccag ccaagcttta caactttgaa
     2401 gcaggttact tggctgagaa tggtccagca gatatcacta tttttgatgc caaggctgac
     2461 cgctttgtgg actcccattt tgcttccaaa gcagctaatt caccattcat cggtgaaacc
     2521 ttaaaagggc aggttaaata taccatctgt aagggacaaa tcgtctatca agcttgatag
     2581 gagttagaat atgaattatt ttcgaaaacg tagggagaga caagcgaaat ctaatagtgg
     2641 aatttactgt cccgcagcta atcgttccaa aattcaatat gaaactaaag aaaaagctga
     2701 ccatgcggtt caatatgata acggaggttt agttagaagc tattattgtc gtacatgtgc
     2761 gtgttggcat actacttcaa aatctaataa acctccgcta agtttgaaaa actatggtct
     2821 gaaactcttt ggtttagata aatcagaata gaaagagaag tatgtataag acaaagtgtt
     2881 tacgagagaa gttagtatta tttttaaaaa ttttcttccc aatcctgatc taccaatttg
     2941 ccaattattc tgcctctttt gttgatactg caatgacagg tcaatacaac actatggact
     3001 tggctggtgt atctatggca accagtatct ggaatccttt ctttacattt ctaacaggga
     3061 ttgtgtcagc cttggtgcct atcattggtc accatcttgg tcgaggcaaa aaggaagaag
     3121 ttgcgtctga tttttaccaa tttatttatt tggccttggg cctatctgtg gtcttgctgg
     3181 ggatggtact tttcttggca ccaataatct tgaatcatat tgggttagaa gcagcagtag
     3241 cggcagtagc ggttcgctat ctttggtttt tatctatcgg gattatcccc ttgttgctct
     3301 ttagcgtcat tcgttccttg ctggattcgc tgggcttgac caaactgtcc atgtacctca
     3361 tgcttttgtt actccctctc aatagcggat ttaactatct cttgatttac ggtgcctttg
     3421 gtgttccaga actgggaggg gctggtgctg gtttaggaac atccttggcc tactgggtct
     3481 tgcttgggat ttctgttctg gttttattta aacaggagaa gctcaaagcc ttacaccttg
     3541 agaaacgaat tccacttaat atggataaca ttaaggaagg agttcgttta ggtctgccta
     3601 ttgggggaac tgtcttcgcg gaagtggcta tcttttcagt ggttggcttg attatggcta
     3661 agttttcgtc cttgattata gctagtcacc agtcagctat gaacttttca agtcttatgt
     3721 acgcctttcc tatgagtatc tcatcggcta tggctattgt cgtttcctat gaagtgggag
     3781 ccaagcgatt tgatgatgcg aaaacctata ttggtctagg aagatggact gctctcattt
     3841 ttgcggcctt caccctaacc ttcctttaca tttttagggg aaatgtggcc agtctttatg
     3901 gtaacgaccc aaaatttatc gatttgacag cgcgtttttt aacttatagt cttttcttcc
     3961 agttagcaga tacctttgcg gcaccgcttc agggaatttt gcgggggtat aaggatacag
     4021 ttattccttt ttaccttggt ttgcttggtt attggggcgt agcaatccct gtggctacgc
     4081 tatttgattc cctaacagat tttggagctt attcttactg gatcggcttg attattagtt
     4141 tgattgtgag tggggcgctc taccgttggc gtttaactgt gattatgaag agatttgaat
     4201 ctttagcaaa atccaaacgc taaaaagttt gtgaaaaaat attcttgaca agaaaatccc
     4261 ttgttttcac ggggttttct tttttatttt gtgaaatttc ttttagaaaa actttgacag
     4321 tatttgccaa aagcggtaaa atagtaaggt aagaagaaag ttagaaaggc aagaagatgt
     4381 caactttaga taaaaatctt ttgctagaaa tgttccgtaa gatggaagaa atccgtcgca
     4441 tggacttaaa aattgcacaa ttagtaaaga aagggaaagt gccaggaatg acgcactttt
     4501 ctgttggtga agaggcagct aacgtggggg ctatgttagc tctcaatcca gatgatctga
     4561 ttacctcaaa ccaccgtgga cacgggcaag ctattgctaa agggattgac ctcaacggaa
     4621 tgatggctga aatccttggt aaatacactg gaacctgtaa agggaaaggt ggatctatgc
     4681 atatcgctga ccttgatgct gggaaccttg gtgccaatgg tatcgtaggt ggtggtatgg
     4741 ggatcgctgt cggtgcagcc ctcagtcagc aaatgcaaaa taccggtaaa atcgttgtct
     4801 gcttctttgg agatggtgcg accaatgaag gtgttttcca cgaagcagtg aacatggctt
     4861 ctatctggaa cctgccagtc attttctatt gcattaacaa cggttacggt atctctgcgg
     4921 atatcaagaa aatgaccaat atagaacata tccatcaacg tagcgccgct tatggaattc
     4981 ctggaatgtt catcgaagat ggtaacaatg tcatcgatgt ctatgaagga tttcagaaag
     5041 ctgtggacca tgttcgcagt ggcaatggtt cagtcttgat tgaaagtgta acttatcgct
     5101 ggctcggtca ctcatcatct gaccctggta aatatcgtac gcgtgaagaa gtggaattgt
     5161 ggaaacaaaa agatccaatc gaaaacctcc gcaattacct tattgaaaat aacattgcaa
     5221 gtgccgaaga attggaagaa atccaagcgc aagtaaagga agcagtagaa gcttctgtta
     5281 aatttgcaga ggaaagccca ttcccaccgc ttgaatcagc ctttgaagat atttacgcag
     5341 actaaggaga aagagataaa atggaaacaa aaacaatgtc cttccgtgac accattatcc
     5401 ttgctatgtc tgaggaaatg cgtcgcgatg aaaatgtgtt cttgatggga gaagatgtcg
     5461 gtgtcttcgg aggagacttc ggtacttctg ttggaatgct tgaagaattt ggtccagaac
     5521 gtgtccgtga ctgtccgatt tctgaagctg ccatctctgg agcagcagca ggagcagcca
     5581 tgacaggact tcgtccaatc gtcgatatga ccttcatgga cttctctgtt attgccatgg
     5641 acaatatcgt caaccaagct gctaaaacac gttacatgtt tggtggtaaa ggtcaggttc
     5701 caatgactgt tcgttgtgca gctggtaacg gagttggctc tgccgcccag cactcacaat
     5761 ctctagagtc ttggtttact cacattccag gacttaaggt tgtggcacct ggaacacctg
     5821 cggacatgaa aggcctgctt aagtcttcta tccgtgataa caacccagtt attatacttg
     5881 agtacaagtc agaatttaac caaaaagggg aagtgccagt tgatccagac tacacaattc
     5941 cacttggggt tggtgaaatc aaacgccaag gaacggatgt aacagttgtt acttatggaa
     6001 aaatgcttcg ccgtgtggtt caagctgctg aagaattagc agaagaagaa atttcagttg
     6061 aaattgttga cccacgtacc cttgttccgc ttgataagga tatcatcata aactcagtga
     6121 agaagactgg taaggttatt ctggtcaacg atgcccacaa aacaagtggc tatatcggtg
     6181 aaatttcagc tattatttca gaatcagaag catttgacta tctagatgca ccaatacgcc
     6241 gttgttcagg agaagatgtg ccgatgcctt atgcacaaaa cctagaaaat gcaatgattc
     6301 caacagttga aagtatcaaa gatgcaatcc gaaaaactta taacaaagac tagagttaca
     6361 taatataagt tatgtaacta aaataaagct gacgagaaac tttgtatctt ttaggtgcag
     6421 agctcttcgt cattaatatc ttatattcga gcacgggcta aaagctcgga aaaaagataa
     6481 atctccttgg cttcatcgaa gccatcgtcg atttcctatt tttcagtcgc ttttgacgcc
     6541 ctttgtatca taaatagaat tggagaggtc atggctgatg acaagctaag agcgactcct
     6601 gcagctagaa agttagcgga tgatttaggg ataaacctct acgacgtttc tggctcaggt
     6661 gcaaacggtc gtgtccacaa agaagacgtg gaaacttata aagacacaaa cgtggttcgc
     6721 atttcgccac ttgcaaaacg aattgccctc gaacataaca ttgcttggca ggaaatccaa
     6781 ggaaccggtc atcgtggtaa aatcatgaag aaggatgttt tggccctgct tcctgaaaat
     6841 atcgaaaacg atagcatcaa atctcctgct cagattgaaa aagtggaaga agtccctgat
     6901 aacgtaacac catatggtga aatcgagcgt attccaatga caccaatgcg taaggttatt
     6961 gcccaacgca tggttgaatc ttacttgact gcgccaacct tcaccctcaa ctatgaagtt
     7021 gatatgactg aaatgttggc tcttcgtaag aaggttcttg agccaatcat ggaagcaact
     7081 gggaagaaga ctactgtaac agaccttctt tcgcttgcag ttgttaagac tcttatgaaa
     7141 cacccataca tcaacgcttc attgacagaa gatggcaaga ctattatcac tcacaactat
     7201 gtcaatcttg ccatggcagt tgggatggat aatggattga tgacacctgt tgtttacaat
     7261 gctgagaaga tgagtctttc agaactggtg gtagccttta aggatgttat tggccgtacc
     7321 ttggatggta aattggctcc aagtgagtta caaaattcaa cattcacaat cagtaatttg
     7381 ggaatgtttg gtgttcagtc ctttggtccg attattaacc aacccaactc agctatcctt
     7441 ggtgtcagtt cgacaatcga gaagccagtt gtcgtcaatg gtgaaattgt gattcgccca
     7501 atcatgagtt taggattaac cattgaccac cgtgtcgtag atggtatggc tggtgctaag
     7561 tttatgaagg acttgaaaga gttgattgaa acgccaatct caatgttaat ttaagagcaa
     7621 gagtattcat ttttaagata tagataaagg aaggaagaca tggccttaga aataattatg
     7681 ccaaaagccg gcgtggatat gacagaagga caaatcgtcc aatggaataa aaaagtcgga
     7741 gaatttgtaa aagaaggaga aatccttttg gaaatcatga ctgataaagt cagcatggaa
     7801 ttggaagccg aagaagatgg gtacttgatt gccattctca aaggagatgg tgaaactgtc
     7861 cctgtaacgg aagttatcgg ttaccttggt gaagaaaggg aaaacatccc aacagctgga
     7921 gcagcatcgc cagaagctag ccctgtacct gtagcaagta cctcaaacga tgatggtaag
     7981 agcgatgatg cttttgatat cgttgtgatt ggtggaggtc ctgctggtta tgttgcagcc
     8041 attaaagctg cccaactcgg cggtaaggtt gcccttgttg agaaatctga acttggtgga
     8101 acctgcttaa accgtggatg tattccaacc aagacctacc ttcatagcgc tgaaattatt
     8161 gaaaatatcg gtcatgctgc aaatcgtggt atcgtgattg aaaatcctaa cttcactgtt
     8221 gatatggaaa aacttttaga aactaaatct aaagttgtta atactcttgt tggtggtgtt
     8281 gcaggacttc ttcgtagcta cggagttgct gttcataaag gaattggtac aatcactaaa
     8341 gacaagaacg tcttggtaaa tggttctgaa ttgcttgaaa ccaagaaaat cattcttgct
     8401 ggtggttcaa aagtcagcaa gatcaacgtc cctggtatgg aatctccact tgtcatgact
     8461 agtgatgaca ttcttgaaat gaacgaagtg ccagaaagcc ttgttatcat cggtggtgga
     8521 gttgtcggta tcgaactcgg tcaggccttc atgacatttg gttcaaaagt gactgttatc
     8581 gaaatgatgg accgtatagt tccagctatg gatgtggaag tttctaagaa ccttcgcttg
     8641 atccttgagc gtaaaggaat gaccatcttg actggtacta aactgcaaga aatcattgag
     8701 gaaaatggtc aacttcgtat caaggttgaa ggaaaagacg atatcatcgc aagcaaagct
     8761 cttctttcaa ttggtcgtat gccagacctt gaaggtattg gagaggttga gtttgaattg
     8821 gatcgtggtt gtatcaaggt caacgaatac atggaaactt cagttccagg catttatgca
     8881 ccaggtgaca tcaacggtac taagatgttg gctcacgcag ctttccgcat gggtgaagtt
     8941 tccgctgaaa atgcccttaa aggaaatcat gcagttgcca aattgaattt gactcctgca
     9001 gccatctaca ctcttcctga agtagcagca gtaggtttga cagaagaaca agcccgtgag
     9061 aaatacgatg ttgccatcgg taagtttaac tttgctgcta acggtcgtgc tattgcatct
     9121 gacgcagctc aaggtttcgt aaaagttatc gctgataaga aatacggaga aatccttggt
     9181 gtacacatta ttggtcctgc agccgcagaa ttaataaacg aagcatcaag catcatcgaa
     9241 atggaaatca ctgttgagga aatgctgaag accatccacg ggcacccaac ttactctgaa
     9301 gtgatgtacg aagcgtttgc agatgttcta ggaatggcca tccattcacc taagaaaaaa
     9361 taaaacgaag atagattaga ctggaaggtt atttccagtt tctatcatat aaagtaaagg
     9421 gatatcatga aatacattat caatcattca aatgacactg cttttaatat tgccttggaa
     9481 gaatacgcct ttaaacacct tttggatgag gatcaaatct tcctactttg gattaacaag
     9541 ccatctatca ttgttggtcg tcaccagaac actattgaag aaatcaaccg tgattatgtt
     9601 cgcgaaaatg gtattgaggt agttcgccgt attagtggtg gtggagctgt ttaccacgat
     9661 ttaaataacc tcaactacac gatcatctcc aaagaagatg aaaataaggc atttgacttc
     9721 aagagcttct caactccggt tatcaatacc ttggctcaac tcggggttaa agctgagttc
     9781 acaggtcgta atgaccttga gattgatggt aagaagttct gtggcaatgc ccaagcctat
     9841 atcaacggcc gtatcatgca ccacggttgc ttgctctttg acgttgattt gtcagtcctc
     9901 gcaaatgccc ttaaggtttc aaaagataaa tttgaatcaa aaggtgtgaa atccgtccgt
     9961 gcccgtgtaa ccaatattat caatgaatta ccaaaaaaaa tcacagtcga aaaattccgt
    10021 gatttactct tggaatacat gaaaaaagag tacccagaga tgactgaata cgtcttttca
    10081 gaagaagaat tggccgaaat caatcgcatc aaggatacta agtttggaac ttgggactgg
    10141 aactatggta aatcacctga atttaacgtc cgtcgtggaa ccaaattcac tagtggtaag
    10201 gttgaagtct ttgctaacgt tactgaatca aaaatccaag acatcaagat ttatggtgac
    10261 ttctttggta ttgaagacgt tgctgcagta gaagctgtcc ttcgtggggt gaaatacgaa
    10321 cgcgaagatg ttcttaaggc gctaaaaacc attgatatca cacgctactt cgctggtatt
    10381 agccgtgaag aaatcgctga agcggtagtt ggataaatca aaaagaagtt ggccaactaa
    10441 ccaacttctt tttttgatat ttatttacat aatttaaaat acgtaaaatc ataaactatc
    10501 cagagcattc ttttgttcat cactaacaat atgggtatag aggtcagtga cttgtgtgct
    10561 agcatgtcct agttggtgac tgactaaaac ttgtgattta gtcgcatcat agagcctagt
    10621 tgctagtgta tggcgcagtt tatggggtgt tacacgcact ttaaaatcct ctgagtattt
    10681 agcaaccatt ttctcaacgc tagaagcatc gatacgatta ggaacacctc tgtagagagt
    10741 taaaaaaagg gctgtatctg ttttttccgt tttatagcgt tgattccgaa tggccagata
    10801 attctctaaa taaggtttag caaaagcagc gacattgact gagtcacgtt tgccaccttt
    10861 tcgagtaaca tcaataacca tcatttttag attgagatct cttagatcta gattaacagc
    10921 ttcagataag cgaacaccag atgccaagag aagggcaata atggctaaat ctcgttcttt
    10981 atttttgttg aatgatgaga gagctcgatt tgaaagctgt tgtgggtgct cttgatcgat
    11041 ataagttaga aaaccttctg tttcatcacc tagaaagagt ttttgcttga tattttcagc
    11101 tctggcagca agggtttctt tctttttctt ggttgaaact tttttcatta cattacgata
    11161 gaaataaggt tccccctgat cgttttcaac ctcctcggtt agatacttgt aaagactaga
    11221 aagtgctgat aaggttcgat tgatagttgt ctgtgaaaca ccttgttttg ttgtattagc
    11281 attcagcaag ggacgttcac gtagataaag gataaaggat tccatgtctt tcttagacat
    11341 attttccaaa actgataaag gaatatcgga tattttatca gcgtttgaaa taccagactc
    11401 caaaacccag ctgaaaaatc ggtcatattc cttaaggtat tcgtacaggg ttgtaaaact
    11461 gtagggcaca gccagtttag attggtagta ttccagaaca taccagggca tgagttgttt
    11521 tagtttgtcg attcgttcca gtaaaatctc acgtttcatg tattttctcc ataattaagt
    11581 atactagtag tatagcatag acttgtacat ttttcaagaa aattatagtt tttcagaaag
    11641 atgttatagg agtttttcaa agtgataaaa agacttagac ctacaaacaa aacagaataa
    11701 ggaaaataat aaaaatctca cccactaaac ttctgttaat actacatagc tagaaattgg
    11761 tttgattgtc ctgattgttt tatcctattt ctatttcatt tcactatata attgctattg
    11821 ttttcttttt catgatttta atcttactgt acagatttga tacagtaaac tcctttctag
    11881 ctttatactt tatcatttct aacttaatta tagtcttatt tttaataaag ttcaattatt
    11941 tatatgtaaa attcctcatc agtaaaaaat aaccgatctc atttctgaga atcggttttc
    12001 taaataaatc aagccgaata aatcaagccg atcatttaca taacataaat tatgtaaatg
    12061 atcgtactac aacaacaaat ctttgacttt tccaatttca ctttttggaa taaccaggtg
    12121 aatcatatca cccagataca ttctggttga gccgttaact gtttggctct tgccattatg
    12181 gacttgagtt gtgatgagga cgttgtgtgg taagttgagt tcatgaactt gtttcccagc
    12241 aattttatca gaaactggta tttcgataag tgtaacttct ccttcgctag atacttcttc
    12301 tggaagcatt ttttccagca tggcttcata gactggcgta cctttgagca aatccatgat
    12361 aatataagaa acaagagtga caagaccaag tggcatgagg ttgcgaatat ctcctaccat
    12421 ctcagttacg aggatcatag cagttaaggg agcttttgat atggctccaa aatagccact
    12481 cattcctaga atgacaaata tagggaattg ctcttgactg acaagtccaa gattgacaca
    12541 gataacacca actaaggcac caagcaaaga accaagagct aaaatgggga ggaaaattcc
    12601 tcctggcagt ccacttccat agctaatcat actccaaata aagcggatta aaaagtaagc
    12661 taataaaact tggaaactaa aattttgttc agttaaagaa aggacaagct gatttccgcc
    12721 accaatgatt tgaggtaaga agattccgac tggtatgata aggataaaag ccaagatggg
    12781 ataataagcc ctatccaaat ggattttttg accaatcaag tcataaactc ttccaacgtt
    12841 taatacagct ttctcataga gaaaacctga aaatccaagg aaaattccca tgacgagata
    12901 tatccaatac tgatctaggg tcatgggagg aatgttatct ggcatatcca atactggtgt
    12961 caaaccgaac atgagtagag acacaaagtt tgctacgatg ctggctgcta gagttgagac
    13021 ccagaaaaag cgcgaaaaat ggtgatagac ttcttctaca acaaagagaa gtgctgcaat
    13081 aggagcatta aaggctgcgg ctaaacctgc tgcagctcca ctggcaatca aggaacgttc
    13141 ctctactgga ctggatttga gccacttggc aattccttta ccaccaactg ctccaagttg
    13201 aatgctgggt ccctctcgac ccagcatgag tccactggca atagcaagaa tacctagcac
    13261 atattttttc caaagaatgc cccaccagtt gagggacatg aggcctttca gttcggcttc
    13321 gacttgagga attcctgagc ctttaatatc tttttctgac cgtgttagtt tggcactgag
    13381 ccaacagatg agtatataaa acaaaaccag tacaaaaaga ttgcgcacta agtacccttg
    13441 atcttgataa actccttgta tcaggtggaa gcccttttca attaagaaac gaaaggatcc
    13501 gacgataatt ccaacgatga ggccgacaat gattcctcga ccaacttggg atagtatagt
    13561 gctggatgca aaggcgaatt ctttcttaga acggactatt tccgactgtt cctccatggt
    13621 atttcctttc aattaatttt cttttttacc taaaaccagt gatttaacgg gttcaaagct
    13681 ggttcggtga attggggtaa ctcctagttt tgtgaggcct tccagatgtt tagctgtgcc
    13741 atatcctgca ttagtagcga aatcatagcc agggaactgc tgatcgtatt ccttcatcaa
    13801 ttcatcacgt gttaccttgg ctactataga tgctgctgcg atagagaggg agttggcatc
    13861 tcctttgata atggaggttt gtgaaatgga caagtccagt ttcatggcat caatcaaaag
    13921 gtgctctggt tgagggctga gctgggagat tgcttcttgc atggctagtt tggttgcttc
    13981 atagatgttg acttggtcga tgacctgatt atctatgata ccaattccaa tcgacaaggc
    14041 ttggtcttga acggcttgga aaatctccag atgtttcttt ttaggaattt tcttgctgtc
    14101 gttgagacct ttaatcttac aatttttagg taaaatgacg gccgcagcga ctacaggacc
    14161 agcaagagga ccacgaccaa cctcatcaat acctacaatt aaggtcaatc cttgcttata
    14221 aagttctttt tcataagaaa gcatggattc caagcgcaaa ttttcatcta attcagcttg
    14281 aatggctctt ttacgcttgc tgatttcctt ttgaactcct gagcgattat ccttttcaag
    14341 ctctaaaaaa atagggcttt ctaactcctt gactgtcaca aggagttctt tgatttcttt
    14401 aatcgttgcc atcgaggtct tccaatgtat ctaaggtata gttaccgagt ttgccatcac
    14461 ggacttcctt cacgaagaga ctgtaaaaac ggtcatagtc atcacggaaa ccgagggcgc
    14521 gggtcatatc cataataatc acaggcgctt cttcttcaat tttcatttgt ttgaagcgtt
    14581 cagccagctt ttctggataa tgttctttga aataattgat accaaaaatg gtaacctcat
    14641 ccataggaag caactgatcc ttgatagctc cagtcaatgc caacttaagt gcaacagttt
    14701 catcctcaaa cttaggccag agaatccccg gtgtatccaa gatttccaga tctttattgg
    14761 ttttaagcca ttgttgacct tttgtgaccc ctggcttgtt tccaacaaca gcaatctttt
    14821 taccagccaa acggttcatc agagtggatt taccagcgtt tggaatcccg ataatcatgg
    14881 tacgcaaggt ttcaatctga atcccacgtt ctttctggcg agcaatctta tcagccatga
    14941 gcttcttggc cgcatctgtt acaactttta cagtcacttg ctctttggag ttgatagcta
    15001 gcgtctggat ttcttgtgat tcaaaatact gacaccattc cttggtcatt gctggatcag
    15061 ccaagtcggc cttgtttaaa atcaagagtt ttggtttatc accaacaatc ttggtcaaca
    15121 taggattttg actagataga ggcaagcgtg catctactaa aatcgtcaca aaatcaacaa
    15181 attttaaatt ttcctgcacc tgtcgacgcg ctttagacat gtgaccagga aaccattgaa
    15241 tagtagccat tgagtttttt cctttcgtag ctctgaagct gttaatctag aactaagaga
    15301 tctcaatcta aaaatgaatg atgtccaaac agttcttgtt ttatgatata aaaatctact
    15361 ttatattata tcatgccttc tttattttgt ccgatgatag ccttttaccc tatcttttac
    15421 cctatataga aaaaagccat caaatgatga cttttcagag ggagcaaaaa actgtcctct
    15481 ttatatttta aacatttaaa tgtcttcttt aaacagttta ttaaagaaac cgtctgtgtt
    15541 tttaagaagg gctttgaata ctttggattt caagtctact gtatttttga aatgatcttt
    15601 aattttcgga tctgacatac catcaatatc tttttgaaca gcttcagcaa ataaagtttt
    15661 caactgagca taatttgtaa tttgacgacc atcaatttca atagcagtaa atcctttttc
    15721 tgcttttgac ttaacatctt tgaagtattg tttcttccac tcttcaagat tattgaattt
    15781 atccttagat actttcttga taatgaaatc atcacccaat aattttttat tggttttgtc
    15841 agcttcgcct tgatatttgc tagatgcata actaatgaat ccattttcat aaccaaaata
    15901 gccccacata cggaaagtat tatgcttgaa tgatgcagct ccaggtgctc cttggctagt
    15961 attaccacca tagataccgg tcattatatt aatatttacg taagcactat caaaatcttc
    16021 tggattatat gttctgtcac taggagcgcc atgttttgtc atcaaattat tgttgactaa
    16081 atcatcaatg ttgttgataa caattttctt cttctcatct tcagttaatt cacgaacttt
    16141 atcaaattga tgtagctctc catttttgcg atattgtcta tccattttct tgaaccatcg
    16201 actaatatta ccatgtaatt tagggataac agcatcagcc tcaagatggt ctaacatcat
    16261 aagagcatca ttataatttc tcatataacg gtcgatatct tcacgagttt tcaatttatc
    16321 tggatcataa ttataccatt ggtcaccgtc attttcacga tgataagcca tgttaagacc
    16381 aagagcacca tattcaccgt taccagattt atcaggtgtc tgcaacatac cttgcgcata
    16441 ggcttcaacg tctgtacctt gacggtgtct atgcccaccg aagtaaagca ttctatcgtt
    16501 tacgtgtgtt gtttcgtgag taaaggctga aataccaaac ggactaatca tatttgttcc
    16561 catgaaataa acttggtcat tattattggg atcttggaaa atagatgcca tagctcccat
    16621 gtaccaattt gtagtatgat aacgccaagt aggtccatat aattcacgaa taggtgcaat
    16681 tggtttatta ttcttatcat aacccatacg atttacacct tcgacgttat gatagttttg
    16741 gttatcccaa acaggtgttg gaaccctatt ttgactcttg agtaattggt cacgtacgct
    16801 tggcaatgct aaacgcgacc agaagtcaag ataagtttgt tgtgcgtgag caacttcttt
    16861 aattttatct ttaaatgctt ctcgttcagc ttctgtatac ttaccatatt tttcaaaaga
    16921 gctataagcc attgtattgt aagtcgaaat caagaacata tgtgcattct taagagttaa
    16981 tagaggtagg atcatacgat tatgaacacc attattcaaa ccatcaaatg cacgatgtcg
    17041 tttattaaca aaatctgggt tcgttgtttt aggctccaca atgtatacgt tcttagccgc
    17101 atggataaac caatcattta aatcagtatc gttagtgaag agacgcatgt tgtaatctaa
    17161 gaagccatgt aattcagact taccaatagt tccaccaatc atatcacgat aagcatccaa
    17221 agttctgtca cccttgatat ttcgctcact tgatccaatt cgaatcaaga agtcaagaag
    17281 gtcaactgac ttaccataga aatcaggttt aaacatcatc aagtttttga tagtcatatc
    17341 cccatacttt atatcatagt aacgattaag gtaagtaaga gccatcacga ttttagcttt
    17401 attttcatcc accttcttaa caagtgcttt catagctgct tcgtcactat ttaattgatg
    17461 gtcagcattt tcaatcaaag atttgaccaa tttatcaaga ttagctttcg tttcagaaaa
    17521 actttcttcg aaataaaggt ctcggatata accattctta cgctcatccg aattagcatt
    17581 aggatctcta gatgtatctc gtttatccat caaagcacgg acttcgggag aaattaattc
    17641 aacagttgct aacctatctt taatgtcttt aatcaattga tcacgatttt tatcaaccat
    17701 gtttggtgta taaacaatgt catctaatcc atcgatacta tactcacgaa cttgcgctac
    17761 tttagactct ttttgatgaa cagctttgat ttctttagtc ttatctgcat agtgaatcat
    17821 cacatgatca atatctgata aatcggtcac gaattgacca tccttcatac ccgtaacaga
    17881 aaggacttct ttcttagcta agtttgaatc ttctgcaagt ttgttacctt gattgacaat
    17941 ccattctttg ttataaaatg gttgcagttt ctcaatatta cgataagcca gatctcgatc
    18001 tactttatag tcttgggttg acttatattc atcttctctt ctggttaaac gatttaagcg
    18061 attgaccaca ggttcattga tttcgtattt atctgcggta attcctgtag cttcaatttt
    18121 agattttgcc tcttcctcag aaataggtct gatacgattt ttatcttttg aacgctggta
    18181 gctagaatgc ccatcactaa cacctattac aacataattt cgtcttacat tatctcctgt
    18241 ccagtagcca tcatcataat caatatcact agaaccatag aaaatttcac cattaggtac
    18301 cttcatcatg gaaactgaat cttcgacaga accgtggtgc ttcatgcttc ctacaacacc
    18361 accactttca atcgcctcag ttacttgaat tgttccctta gcaatagatt ttttgattgc
    18421 tccttcctga cgaacagtat tgttatttcc ttcattttgt gtccaataag caatgcccgc
    18481 agccttggct ttcttgccaa taagatttgc gttaacatac gcgcgttcga cgagtccttt
    18541 ccagttctca ccaacgatac cagtcaagaa ttgtccacca tcgccgacag aagttacgtt
    18601 accgataaag gccacatttc tgagtgtacc ttggttatca atcttatcaa taaatccaga
    18661 tacccaatct ttacctacta tattaccttt aaccttaaca ttttcaatgg tagttccacc
    18721 tttaataata ttcgctacag ctgcaacttg gttcgcccat ggcatattta tgtcaacatt
    18781 accaagatta atattcttaa tcgttccacc aataacattg ccaaataacg gacgtgacaa
    18841 gttatgaatg gtatagtgat tatcaccatc actcaagagc ttacctttga aatctttcgt
    18901 aacatatgat ttaccaaatg ctgatacatt tgtggcatta aggtcagcac ccaatttaaa
    18961 ctcgtcattt ggatgttctt gcatatctct cacaagttca ttgaaattgt aatatacatt
    19021 attgactttt ggaactggtt tttcaatgta atgaatgtat tcatttctag tcttagatgg
    19081 atcgacatgt tgaattaaat cttgagcgct tgctgtaatt ttataaagtt ctttttcttt
    19141 ttcagttact aactcaatct tatcaactgc taaacgagtt actttattat cacgactagt
    19201 gatttttaag tacattttct tcacatcttc atcagaaggt ttttcgctca tgaaatcact
    19261 aggtatttca gtaccatcat catttacctt cactaaatta gtagatgaaa tatttttaat
    19321 ttcgaccttt ttcaactcca aacgcaaagt tttttcatcc agtttagacg tttcagaacc
    19381 ttgaccacga tcataaatca ttgttgttgc aatcttataa tctttaaaca aatccaaatt
    19441 ttgtacagcg tcagttaatt tttctttaga taaatcaacc tttttaacta ctgtatcacc
    19501 atctttaatt tcagctataa tacttgatat ttcagcatta tctttattat caagctcata
    19561 atttaagttg gcagaacgat tcatagcatc ttctgttact ttggtcaagg tcaaaacggg
    19621 aactgttttt tcttttggat tttcttttgt accttttaca agaattttag gtttcatttc
    19681 tttcaaaatt gttaccgttt caactggttc actaattttt ttgccatgta actcttcata
    19741 gctagtaaca atttgacgtt cgccatcctc accaacttct ttaacagaat catcgcctat
    19801 aaatttgcta ggatcagatt cttctatagt ggttttagga atagtctctg tacgaatatc
    19861 ggtatgtaaa gaaggcaact cttctctttc tgatgcaact tctgaaactg tagatattgg
    19921 ttcagtatac tctggaatgt cgttaacagg tggttcaatc aagtttccat tttcatccac
    19981 tcctgttgta cctactggtt cagtgtatgc tagtttctca tgaacttcag gctcaacaag
    20041 gtttgcacct attggttgcg tatagtcagg cttctcatga acttctggtt cgcctttgtc
    20101 agtcacaaca gcttctggta atgtcggttg tacttccggt tcgcctttgt cagtcacaac
    20161 agcttcgggt aaggctggtt gaacctccgg ttcccctttc tctgttacaa ctttgggttg
    20221 ctcaactggc gaaacagttg atgctggaga aaccgacgaa acagttttat catcaagctc
    20281 caagtaacca acatatctgt aaccagaaat ttgcaacaca ccatcacgtc cagactcatg
    20341 gatgttagca ttcaaattaa gtgctgaagc agttgatagt gtaactaaac ctgtcgcccc
    20401 tacaatcaaa aatgtagcta tttttttatt tctattatct tttgtgataa tcacaataag
    20461 actcccgata gctaacaaac ccaatgcagt cataatagat tgagaactgc ctgtgtttgg
    20521 tagtgcgtct ttttcataat ccaaagcata tgactctttg gattcatcag gtctaccttg
    20581 tttgagttga tcacgttcag tttgtgtcaa actactataa tctaagtaat gataagtcga
    20641 tgcaccaata actgacggtg caaataaaag actccccaag aataccgaac caacaatacc
    20701 ctttattttc cgaatggaaa atttatcttt ttttaataat gacaattcta atcctccaca
    20761 ttcacttttt atttcctaat agtaaacact attttttatt ctcaaaaatt gaacttctaa
    20821 aatcatttgt ttggtcaaga taagctttat atattgcttt tttcagttta agaactctac
    20881 tatttgtttc tgggtaaaat tttgctacgt catcttgcgc atcatctctc actgcttcga
    20941 caatcattct ctctagtaca cctatatccg taaccgatac atttcgttga cgactcaatg
    21001 gattattagg attaataaag ttaactctat ttagtttact gaattgtttt tctctttcct
    21061 tatacatatc cttcttgaat tgtgtccaag ttttatattg accattaaat actttttcaa
    21121 gtactaattc atctgtaact aaacctactt ctttaccata agaattaatc ttacttcccg
    21181 ccgcttttgc atctttttca tattgatttg agatataagg taccatgccc tctttatatc
    21241 cttttgcagc taataattcg aatgctatac ggcgtcccat taaatcacca ggagtccctt
    21301 tctctccact aagagctgaa taaatcggtg aaaataaatc aattgtataa taaccatttc
    21361 tcttatattc ttggtctttg taccctctgc tagtaataat atcattttca attaaactat
    21421 caaaagaatt taatttatta acttcatcca tcgttaatct gcgaacaaca tttgtcgcgt
    21481 atacattatt accgtcttga tcaagatcaa atttattttc aatttttctt agtaactcat
    21541 atttttgatt tgtttctaaa ttagctacag cttttccttc taaatattct aacatataaa
    21601 ttacatcaaa catattatgc atataattat gtaggtcttc tgcactatta aatcgttgag
    21661 ttggatcagc tacttgaagt cttgttgaat tttctgaatc ctcatatttc aagacagagt
    21721 taattgttat tgttggatca tatggatgat ccggagcttg taataatcct tttgcataaa
    21781 actcaggtcc taatccgctt cttcttccat atcctccaag ataaatctct ctatctgagt
    21841 tatgtgtcat ttcatgagta tatgttacag ctccatcttt atccaacata cgatatgcca
    21901 tataatagaa tgcatctccg gtagcatatg ctccgtgtcc attatgaaca acattatttc
    21961 ccgcaggtcc aaagaagtat tttatagctg gatgatcagt ttcaaaagta gcttgatgag
    22021 ttactttgtc tttatctttg tcagtaccaa atttgaaagc atcatatact agaatacttc
    22081 tatataattt ttctttatta tcgttatcta atatcttata ccaataatca taatgatctc
    22141 taaatcgttt agccgcttct ttggcgttat cttctacaaa tttgtttaac ttttctccct
    22201 taggatattc tgaacttcta tatctgtcat aggctccaaa tccaatagta gaaatattcg
    22261 ctatcataaa cactgttttt tcttcaggta aagttaatag tggtaagacc atactttgat
    22321 atttccaaga tggattagtt aatctatcat ataccccaat agaatattta gttccctctt
    22381 ttccttgttt ttctcttccc tcttcaattg tagatttttc ttctacaata tatgcttttg
    22441 tttgtttttt aaaccactca ttgttagaaa ttgttggtaa gaatactttt ctatatcctt
    22501 ctaatgcttt aaataaactt tcagttccat aatttttcgc taataataca ttataagtaa
    22561 ttacattatt ttttgctaat aaattgttaa atccagattt acctaactca ataacattat
    22621 ctaatgcaga actatttgat ttaccaaaga aatccaagtg gtacattatt aaatctttag
    22681 cattggtttc tccataatta aaattatacc agcgttctaa
//
LOCUS       DAVLHM010000036        21351 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLHM010000036 DAVLHM010000000
VERSION     DAVLHM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.036"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(428..2155)
                     /gene="ezrA"
                     /locus_tag="VXE45_001535"
     CDS             complement(428..2155)
                     /gene="ezrA"
                     /locus_tag="VXE45_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0789551.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2237..4183)
                     /gene="gyrB"
                     /locus_tag="VXE45_001536"
     CDS             complement(2237..4183)
                     /gene="gyrB"
                     /locus_tag="VXE45_001536"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0789552.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVYVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4198..4761)
                     /locus_tag="VXE45_001537"
     CDS             complement(4198..4761)
                     /locus_tag="VXE45_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0789553.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4846..5400)
                     /locus_tag="VXE45_001538"
     CDS             complement(4846..5400)
                     /locus_tag="VXE45_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0789554.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5411..6634)
                     /locus_tag="VXE45_001539"
     CDS             complement(5411..6634)
                     /locus_tag="VXE45_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0789555.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6671..9121)
                     /locus_tag="VXE45_001540"
     CDS             complement(6671..9121)
                     /locus_tag="VXE45_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0789556.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVVLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9321..10250)
                     /locus_tag="VXE45_001541"
     CDS             complement(9321..10250)
                     /locus_tag="VXE45_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0789557.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10390..10677
                     /locus_tag="VXE45_001542"
     CDS             10390..10677
                     /locus_tag="VXE45_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0789558.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10711..12045)
                     /gene="ciaH"
                     /locus_tag="VXE45_001543"
     CDS             complement(10711..12045)
                     /gene="ciaH"
                     /locus_tag="VXE45_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0789559.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12035..12709)
                     /gene="ciaR"
                     /locus_tag="VXE45_001544"
     CDS             complement(12035..12709)
                     /gene="ciaR"
                     /locus_tag="VXE45_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0789560.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12818..15364)
                     /locus_tag="VXE45_001545"
     CDS             complement(12818..15364)
                     /locus_tag="VXE45_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0789561.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15487..15927)
                     /locus_tag="VXE45_001546"
     CDS             complement(15487..15927)
                     /locus_tag="VXE45_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0789562.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15902..16771)
                     /locus_tag="VXE45_001547"
     CDS             complement(15902..16771)
                     /locus_tag="VXE45_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0789563.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16813..17541)
                     /locus_tag="VXE45_001548"
     CDS             complement(16813..17541)
                     /locus_tag="VXE45_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789564.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17549..18028)
                     /locus_tag="VXE45_001549"
     CDS             complement(17549..18028)
                     /locus_tag="VXE45_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0789565.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18039..18737)
                     /locus_tag="VXE45_001550"
     CDS             complement(18039..18737)
                     /locus_tag="VXE45_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0789566.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18730..18996)
                     /locus_tag="VXE45_001551"
     CDS             complement(18730..18996)
                     /locus_tag="VXE45_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0789567.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19062..19988)
                     /locus_tag="VXE45_001552"
     CDS             complement(19062..19988)
                     /locus_tag="VXE45_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0789568.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20063..20878)
                     /locus_tag="VXE45_001553"
                     /pseudo
     CDS             complement(20063..20878)
                     /locus_tag="VXE45_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20882..21202)
                     /locus_tag="VXE45_001554"
     CDS             complement(20882..21202)
                     /locus_tag="VXE45_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0789569.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6461 a         4680 c         3741 g         6469 t
ORIGIN      
        1 tgttttagag gcctatttac cgtggactaa agttgtacaa gaaaaatgca aataagaaat
       61 ctccagatta ggaactatcc gtgagttctc tagtctggag atttttcaat agacttcgtt
      121 attggacggt taccaagtta ctcaaagtac agatttgaag ctgcagataa gactgacgaa
      181 atcactttaa tactaaatga aaatcaaaaa gcaaactaag aagctagcct caggctgtac
      241 ttgagtacgg taaggcgacg ctgacgtgat ttgaagagat tttcgaagag tataaaacac
      301 tgttttgagg tggtggataa atcggctggg taaaaactca atctcaggag aaaatgaagt
      361 aaatctcccc acaactatag aaaaagattt gattctgctc ctcacacaat aaaatctttt
      421 tcttttatta aaaacgaatc gtttcacgtg ttttctcata tgaggtaaca aagcgattgg
      481 ttacaccagg ctctgccact tccaatgctt gagaaatctt atcaaatgaa gcgtgataat
      541 caaattcttt ttcaaaaata tctaaagctt cgttaaatgc ttcttgaatg cgttcatcaa
      601 atgagcgata gcggttagaa tattgcaaga gttgctctgt caaagttgca tattgtacaa
      661 tattataagt ttccgtttct aaagcttcca tatcattcgt tgcaatttca agaactcggg
      721 taacagattc aatgttaatc attttttgtt ctaactcaac cattaaatcc tcggtattat
      781 tgcttgccgt aaagaataac ttcaagaaag tttgtggaat acctggcaga ttgcgttttt
      841 ccatgtatcg cttgatagta tggagacgat tgacataaac attggccttt tgacgtgcat
      901 taatatcatc tttctcaatt tgtgtcaggc gctcactaac tgaaatttgc tcatcttcaa
      961 tatcttttag ttgagtttgt aaatcctcaa gattttcttc aagaactgaa taagcttggg
     1021 gtggttcttc ttgatttgaa gttacctcaa caatagctgc ctcaaaactc tctaattctg
     1081 tctgaatacg acgaacatgg cttgcagctg tctcaggaag taaataggtc ttgttcaaac
     1141 gtgcaatatc ttctcccaat aaagtattat tctctttcat atgttgaaga taagttggaa
     1201 gagttgcaag tagattttcc actactttct gagcagcaat ttctcgagta aaaatatcat
     1261 acaaggcatt gatttcctct tgtgcctgtc cattctcata ttcggcatta tccaattcca
     1321 actgacgaat attctcttgg tttttcttga atgcttcata aagcaagtgg aaacgcgctt
     1381 caatatccgt ttcaacaaaa tgataattag catcaattag tttacgataa ccggcttcca
     1441 aatcctgtaa ttgatctggc aattctgtag aaagcgtcgt aaccaaggct ggaacacgat
     1501 ccacaatatg acttaaggcc aaaatgtgat tttctgtatt atccaaaatc actgcggctt
     1561 ccacagggtc acccgatgaa ttcaaggtta caaattgtga aaattcagat tggatatttt
     1621 ctaattgttt ttcaatttca tccaaggctt gaccatactg ttctgaattt tcagcaactc
     1681 tatgctgaag ttcctcaaat aaatccaaag catgaagaac acgaccacta tttttagatt
     1741 cttgcttctc taagtctgcc aaagcattgc gaattgccgc aatatcttct tcaatcaaag
     1801 taatttgact ctcaatttgg tcaatttgat gactggcctt gagaaaacga aatgaatggt
     1861 tataaccttc tgcttcaaag agattatttt caatatcggc aaaagagttg agagataaat
     1921 cgacccattt ttgattccat tcacggaaag ccacttgact ttgtccaatc aagtgcatat
     1981 tttttacagc ttctacttca tcatttactg gaagattgta tagttcttct tttctttctt
     2041 ctagtgcctc taatctcccc tcgtttcgct tacgtagaaa gattgccact acataagcca
     2101 gaactaaaat gactgcaatt gcaaccatta aataaattag ttgtccatta gacatatcaa
     2161 actccttttt tacttgaaac aatcgtaacg attatatcat attttttaga ccaagggaac
     2221 tacttctccc tattttttag acatcaagtg tactatagac agcattttct tcgataaact
     2281 cacgacgagg ctctactcga tcccccatca acatatcaaa gattttatct gcttctgcag
     2341 catcatctac agaaactcta gccatcaagc gatgttcggg atccatggtt gtttcccaca
     2401 gctgatgatc gtccatttca cctagcccct tataacgctg aatagtcggt ttggtacgac
     2461 cttcactata acgggctaaa gcttcttgga gtttgatttc ttgatctgca cccggctgga
     2521 tatattcttt aatctcgctt ccaaccttga caccatagat tggtggttgg gcaatataaa
     2581 cataaccagc ttctaggatt ggtttcatat aacgataaat caaggttaaa agaagggtac
     2641 gaatatgggc tccatcgaca tcggcatcgg tcatcaaaac gagtttttgg taacgggctt
     2701 tcgaaacatc aaattctgcg ccaaatcctg ttcccatggc tgtgaaaaga ctacgaattt
     2761 cttcgttagc tagaatctta tccatacttg ctttttcaac gttcaaaatc ttaccgcgaa
     2821 ttggaaggat agcctgaaac tcacggttac gaccagattt ggctgatcca ccagctgagt
     2881 ctccttcgac gatgaagagt tctgtttcag cagggttatt agaagaacag tctgctagtt
     2941 tccctggaag gttggaaatt tccaaaccag attttttacg tgtgacttca cgcgcacgct
     3001 tggcagccac acgagccttg gcagctaaaa tccctttttc cacgatacgt ttggcaatct
     3061 gtggattttc catgaggaaa tcggagaagg cttcactgaa gaggcgattg gtaatcttga
     3121 ccacttcgct atttcccaat ttggtcttgg tttgtccttc aaactgtgga tttgggtgtt
     3181 taactgagat aactgcagtt aatccttcgc gaacatcttc ccctgttaaa ttatcttcat
     3241 tgtctttcag taacttattc ttacgagcat aatcattgat aacacgagtc agtgccgtac
     3301 ggaaaccttg ttcatgcgtt ccaccttcat gggtatgaat attattggcg aaactcatga
     3361 cattttcatg gtaacctgtt gtgtactgca tggctacttc aactgtaata tcatccatct
     3421 caccgtctgt atagattggt gtatcaaaga ttacatcctt gttctcgttg atatattcaa
     3481 cgtaactagc aatcccacct tcataatgat aatgcttggt ttgttccaaa ccttggcgct
     3541 tatcagtgat ggaaatttga agaccgcgat ttagaaaggc caactcttga atccgtttat
     3601 ttaatttatc aaaatcaaag attgttgttt cagtgaaaat ttctgggtcc ggtgtgaagt
     3661 gaaccgttgt tccagttcta tctgtatccc caaccacctc aaggtctgca acaacatgac
     3721 cacgacggta ttcttggtaa tgaatcttac cgtttttatg gacataaacg tctaattgag
     3781 tggaaagggc attaactact gacgacccca ccccgtgaag accacctgaa accttgtatc
     3841 caccaccgcc gaactttcct ccagcatgaa ggactgtaaa gacggtctca acagcaggac
     3901 ggcctgtttt ttcctgaata tcgactggga taccacgccc atcatccaca acagtaatcg
     3961 aatcatctgg ctcaataaaa acttgaatat ggctggcaaa tcctgccaag gcctcgtcaa
     4021 ttgagttatc aacaatttcc cagactagat ggtgaagacc ttcttttgag gttgatccaa
     4081 tgtacatccc tggacgcata cgaacagcct ctaagccctc taaaacttga atttgactgg
     4141 catcataatc ctgtgcctgc agatttttga tttcttctgt catcttattc ctttttctta
     4201 tatgtctaat acttgtctta aattcacgat actggtaaac aagtgggtat caagtcctgc
     4261 agcttgacct gcttcgatat caatcggccg atcaccaatg acaagaccag agctaatctg
     4321 atacttttct cttaaataaa gcatggattc gggatttggc tttctcttaa agcctgagct
     4381 agaagtcacc acttctgtaa aataagctgc tatagaggtt ttttctaaaa tttccaaaac
     4441 ctgatcattt cgatgagaga ccaaaaaatg acggccacct tgatttgaaa tgacttccaa
     4501 taggtcagaa actccttcaa ataaaatcgg gtgttcaagc tctctggctt cattttcctt
     4561 gtacttttct aaaaaattct ctaaattggg agcgaatgtc tcaatcgcaa aaggagtaga
     4621 aacctttaaa gcttgataga cactgtcatg gtcttgtgtg ataccataca gtgccaatgt
     4681 ttcaacaaat gcagctgttg aagtttcata attatccagt aaagttccac ctaaatccca
     4741 gatgtaatcg tgatatttca tgccctttat tatagcattt ttttatgaaa aaagcgatga
     4801 tttccctgag ttttccacat aaaaaacgag agaataactc ccgttttact gatttttacc
     4861 aaagacatct tgatagagca ttcctgttcg taaactctct gcgtcccctc ctagttgctc
     4921 caccaactcg taggcaaagg caagggctgt tgaaggaccc cgactggttg tcaactgacc
     4981 atctaccact actgtttcct tgacgtagtg accatcaagg atttgctctt gaacgccgtc
     5041 ataacaagtg tatcgcttat ttttcaatat ctctgcttga ttgagggcaa ttggtgccgc
     5101 acaaatggct gctagtttct tcccttcttg ctcgaagctt tgcaattctt gaatcaaggt
     5161 ctgattatca cgtaaatgtg cagaaccagg catacctcca ggaagaacaa tcatatcata
     5221 gtctgataaa tctccatcaa agacatgatc tgctcttact tggattgcat gcgaacccgt
     5281 tacttgctct tcaaaaccaa ccatatcaca tgtgatattg gctcgacgca agacatctac
     5341 aactgtcaag gcttcaattt cttcaaagcc ctgagctaac ataactgcta cttttaccat
     5401 gattttctcc ttatttaatt tgttttaata caaccttttt ccgtttgaat gggacttttc
     5461 cgctcttttc ttcagctaaa ttagtctggt aactcatcga taaaagcaaa ccaacaccaa
     5521 tcaaattact gataatagct gatccccctt gcgaaatgaa aggcaaggga atccccgtca
     5581 aaggaagtag tccagtcaca gcaccgatat tctcaaagat gtggaagagc aacatcataa
     5641 tcaaacctgt ggaaatataa gtgtagaact ggttatttga tttaagagta atcttcaaca
     5701 tacggtaaat caacatgaga tagagggcaa taaccaggac agagccaata aagccaaaat
     5761 cttctgcaat aaccgtaaaa atcatatctg actctcgaac tgggataagc agattcgaag
     5821 cattaaatcc ctgaccaaat aagccaccac tcccaatggc aatctgccct tgagcctgct
     5881 ggtaagtcgt tgtttgggca aactcaaagg gattgagcca agccaaaatc cgattaattt
     5941 ggtaggtcgg cattccaatc tggtgaagaa aagctcgtcc gtccttgcta ataaagatag
     6001 ctaagaaacc agcaactcct gttacagcag tcacaaatac tgggataata attttccaag
     6061 aaacccctga taataaaacg attcctgaga aaatggctac aaaaaccaaa gccgtcccca
     6121 agtcactttg aagtgctaaa agaactagga ctggaatggt aaagagaatc atccagaaaa
     6181 ttaacaaaaa gtccagcgga accgtgcgtc tccattcctt atgtttcttt gtaaattgga
     6241 caatgacacg agccaacatg aggatatagg atatcttcat aaattctgac ggttggaata
     6301 gggtaattcc atttattgat acccagtttt tggcacccgt tgatgcaact aagcttggat
     6361 tataaaatac aatcggcaag atcataagtc ccaagcctaa aatatataga aagggggtca
     6421 ccttccaaag aaattctgta ttaaagagca tgaccacaaa accaatcaca agccccaagg
     6481 caatccaggc gacctgctgc cctaaaatgg gcagaatatt attgggataa tcatgactaa
     6541 cggctatata gatagccacc acaccgatga ccagtagaaa aaatactggc aagagcaaac
     6601 tgtaatcgac tcttgagtcg agagaacgtt tcatatatac taaccttata ctttcataca
     6661 atactattta tcaaagttca ttaaaaaatc tatcaatagc ctcgtcaact tcggatcgag
     6721 agatggtttt aacagtcgct tcttctgcta gagatgctac tatttgtttg ccgtatcgtt
     6781 ttccgacgat tctcctatcc aaaataagag ttaaggaacg ttggtattca cgtctcatac
     6841 ttcttcccaa agcctgtttt aaacgaataa tggccattgg caattgataa tcataaaagg
     6901 catttttccc ttcttgattc agttcttgat taatcttttt cgtcaagggt tcttgaggat
     6961 tttggaaagg aagcctcggt acaacttgaa tcacaaaagg atggcttgaa aaatcaactc
     7021 cctcccagaa acttgctgca ccaagcaaga tttgttgttc acctttttca aagcgtttct
     7081 ttagctgatg aacatcccca tttttatact gggccaagtg gctaactgta agtaaatccg
     7141 atactgctag aagcatgtct ttagcggtaa agagaaccaa aatcggttgc tggaaagctt
     7201 gaatttccac tagtaaagca gctacctctc tggcatagac ttctaaggag gtttctgtta
     7261 ccagagggaa atctttgacc ataaccactt cttgttcctg ttttccccga gattcaatct
     7321 tgacaaattt ggcttcagga tagcctaaaa ggtctgccaa agaaaccctc tgactaatct
     7381 caagagtagc cgatactccc aagacttggc aactctcagg aagtaaagag gacagaagag
     7441 tacggcctga ttttgtagaa gaaatctgaa ttttcttttg actcgtttca gttacttcaa
     7501 gccagtaatc accttcagct gtaaaatagc gaaccagctc atcaaagcct tctacttcta
     7561 attctgaaaa atactgatgg agattgtcca gagaatctaa gatatttttc ctagatttac
     7621 cagactgaaa ttgttctatc aagtagagac actcaaagcg aatactttct agtatccgtt
     7681 gttgaaccct gttttcttct cctactaaag ccttatcaat taaatcgata atagattgta
     7741 tatcgtaggt ctcttgaagc agattttcta gagctaacaa aatcttttgg acttcatcaa
     7801 taatcagtaa acggtcactg acaaattcag gattatcttc aagtctggtc acgagatagg
     7861 catgattagt cactaaaagc ttgcaagtct ctgccctttc ttgactacgt ttccaaaaat
     7921 cttccgtcac aaataagctc tgggatgata aattcccatc atgacgaagg tctgctagaa
     7981 aatgttggta acggtagagt tgcccgattt catccaaatc tcctgtctct gtctcagtaa
     8041 gccagaccaa gacttgcatt ttaaagcgtc taaataagcg attttcatca ttttcctgca
     8101 aggaatgata aaaggcatcc aacttcagat aattttgtgg tccctttaag ctatgaatat
     8161 ctgtatggaa cacttccttg agacgtttac cttcttcttc catgatttga ttttgaagaa
     8221 tctttgtcgg aacactaaga acaatttgtc gctctttgga ttgagataaa gcgggtaaga
     8281 gatagccata ggttttccca atccctgtcg gcgcttgaat cagagagaca ggttcatctt
     8341 tcaatagcaa gacaacctct ttagcaaaac tttcttgttc ctccctcact tcaaggttca
     8401 acagagaaat atttttagaa aagtcttgag atagttttcg tagctccaga gaagctgccg
     8461 ttttcttaaa atacagacct tgaacttgga ccaagtctgg agaactcagg atagattggt
     8521 tgcgataagt ttcctcaata accaggtagg actcatatag gagagcgtca gccatttcca
     8581 gcaagcgttc caagagacct ttaggaagct gggtcatctt ttcccgtaaa aaaagaagta
     8641 attctgctgt agcttgggca tctgaaaggg ctgtgtgtgc gtgtttaaga ggaattccta
     8701 attctcgaca caaaatcggc aagctatatt tttccagttc agggaaaaag acctgggcca
     8761 attcgaccgt atcaacacga gggtttctta gctcatagcc ttcaaaaaat aaattttccg
     8821 ccaagagatt agcatcaaac tgaacattat gggctacaaa aatcccatcc tccaccaagt
     8881 caaatatttt tctggcaact tgcgaaaaat caggtgcttg cgccagacgt tggtctgtca
     8941 atcctgtcag ttctttgata tgagcatcca agggttcatg tggattgaca tccgtcgtat
     9001 agtgatcgac gatttctccg tcctcaatca cgacaattcc cacttggata attttagcct
     9061 tactacctgt gctagttgcc tctaaatcca ccacaacata gcgattacca atcgttttca
     9121 ttataaaaaa ttataccaaa aaaagggcta tttggcacct gcaaacatag gataattttc
     9181 aaactcaaga acactacttt tcttaaaaat cccatcgaat agagcattct agcctgctga
     9241 tttttgtaaa atagtgaaga aatacgaaaa attgagagaa gaaatgtttt catcttcctt
     9301 ctctcaacga atcatgtatt ttatttaacc atgtcaggat cgtagtcata aaatcctgta
     9361 tcaaggaaac ggtttttagg gtgaagttta cgaacttctt catccagcaa gaaggcttga
     9421 tcatggctaa agttgccctc ttgaatcaag ttacgcgctt ggataaagag ttttgcaatc
     9481 tcaacaaagt tctgaccagg agtgtagagc ccttctagtt tccagcgagt aaagccatgc
     9541 tccaccaatt ctgttaattt gatcatcaaa tcaaggtcat tgttggcaaa gatatgggtc
     9601 ccatgattat cttcaaaaat ggaatagtgg ctctctggat cacttggctc agccaagaag
     9661 aggtcacgtt tatgcgtctt ttcatcatcg atatgtgtaa agttatagta gttttgcaag
     9721 agtggacgtt tagaatgatg gatgacgcta gcaccgtaaa ccaaaacttc agcaggaatt
     9781 tccaaaatct ctggcatttt gaaaagttca gctgatggaa tttcacgcgc caaaacagcc
     9841 tcagatgcac cagccttttg tccccagaag ttaatctgac gactgctagt taccatggtt
     9901 gaagcatcgt agatggtctt aaatgaataa ccatcgcggt taactacgta aaagacgcct
     9961 gcatccccaa tcgtaatata gtctgtcttg atttcttcca agaagtctaa gaaaggcttg
    10021 atacggtcca tcatatcttg gtgcatgaga gcattgaccg caacgagcaa ttccttacca
    10081 gcatcatgaa ccaacttagc gatttcacgt aattggtcat aactaaaggt cgttggcaga
    10141 cgaaggccaa aatctttctc accgacatag atacggtcta cgccagcttc gagtagttgt
    10201 tcaacttgtt caatactttc agcagttgct gtaatgacaa tcttttccat aagaaaaatt
    10261 ataccacatt tctccaaaat cagccatgct ttgaaaatga aaagggactt tattcttttt
    10321 gtaacctttc tgtaataatt ctctgccgaa aaaatgataa aataggtatg tactgttaag
    10381 gagagaatca tgcccgtaag aaaattacaa tcctatgagg tagactatca agaagaatta
    10441 aaccagcagc ttcctcatta ccaagcttat acacctgaag cgcaatctga tgccaatctc
    10501 aaggaaatcc tattttttat taatatcgct gttttttgta tctgtattgc tatctttagt
    10561 tttatctttt tagcattaaa attatcaact gctcttgcct ttgccgcagc aatcggattc
    10621 agcttacttg ttttaaaagt tcaacggtct attatcaaac gaaaacgtag aagataaatc
    10681 caaaatatcg ccccaattgg agcgatattt ttattttttc tttttagatg gtgtctgaat
    10741 ggcaatcttc acttcaaaga ttgttccctt gggtttatta tctttgacag taacagttcc
    10801 ttttagagca tctacaattt gcttggctag ggataatcct aaaccaaaac cacctttttg
    10861 ccgggttcta gccttgtcta ctcgataaaa acggtcaaaa attttctttt tatcttctgt
    10921 cgaaataccg attccattat cagaaacaag taaataaaga ttgcgatcgg tcgccgagat
    10981 aagaaaatca atttcaccat cctcctcagt atacttgacg gcattatcga aaagaatggt
    11041 catcagttgt ttcagaagaa gctgatctgt gacaattgtt cgatggatac gattttcaaa
    11101 acggaagaca cgattatttt ccgaagcaat catctcatag tttgtgaaag ttgtattaaa
    11161 aaagctagtt ggaacttctg caagctccgg cttaatccca tcatctctcc gagctaagtt
    11221 cagcaagctt gtcgttaaaa aacgcatatt tcggacttct tccaaactcg atgcaatgct
    11281 ttcgctcaca tccataatgg tagcttctgg cttacgaaaa agggtctcta agcgattttg
    11341 caaaactgcg agtggagttc gtaactcatg actggcattt tccacaaaag actgttgctt
    11401 ctgcatactc tcaagcaagg gcctaacact gaccctagct agatagagac tggcaagtaa
    11461 agacaaaatc cagaaactag ccatcacgac cacaatcaat tgctcatgct tttgactagc
    11521 ctgctccaac tgactggtat taatcaagac agcagcatac ttgatattgg ttgaaaccga
    11581 actaatattg gtctccatca aaatcacacg atagatttct tcctgcccat agctattaaa
    11641 aacctgaatc tggtagatat gtcctagttc tttcttttct aacttaatct tatccaagcc
    11701 caaaaatcga tttccagaaa gaagttgagt aaagtcttta tcaaagagaa tgacttccgt
    11761 attggaactg acattaggtt ttatttctac tttactagcg tccgccctag cattttctaa
    11821 atctttaatc tcttctgttg ccctatttat agccagctga ataactgctt gaggattttc
    11881 actcagtcca tgaagcttat cgtccaccga agtataaaga ctcgaatgca tgacttgtaa
    11941 aataatcaga gtcattgtag aaaaaatcag ggtgaagaca ccgaagttgc ggataaaata
    12001 actaaagtca tccgcatacc atgttttttt aagtttactg aacatctttt aaaagatacc
    12061 caacactacg caaggtttgc aaattctctg caaaagtggt tccctttaat ttcttacgga
    12121 cttttgaaac atagacttcg acaaccgaaa tcgttgtatc actatcaaat ccccatagac
    12181 ggtcaaaaat ctgcgtctta ggcaaaatca cattttgatt ttgaaggaaa taaactagta
    12241 aatcgaactc tttccccagc aattcgacag gagtatcttc aactttaacg gtattggttg
    12301 ataaattaac cacgatattc ccataagtca aggtgttttc attaaacttc cctgaacgtt
    12361 tgagaagggc ctgaatccgc attttaagtt cttctaggta gaaaggtttg gtcagataat
    12421 catccgctcc cagttcaaat ccatgtccct tgtcatccaa actttccttg gcagtcataa
    12481 tcagaactgg tgtcgtaatt cccttttcac gcaattcttt taagacttgg aaaccatttt
    12541 tttctggcaa catcaaatcc agcaaaatca agtcatagac accactctca gcttcgtaga
    12601 gaccttcttc tccatcaaat acctgcataa catccgcaaa atcgtctaaa aagtcaaata
    12661 ctgaatttga cagacctagg tcatcctcaa ccaataagat ttttatcatg agaaactcct
    12721 ccttattaaa actattatac caaatttgcc ttaaaaaaaa ctcaactctc tgcattttac
    12781 atgagatagc tgagttttct ttttatttta ggcttattta tgcatttccg tattgaagaa
    12841 caactgcttc gactgcagct ttttcacggc taatcaagtc aacacgtgct gcaatttcct
    12901 tgattcccat accgatgtta cggctaagag caaggtcaga aagttgcggc tcaaagaact
    12961 ccttgtattc cgccaagcgt tgctgagtct taaatacatg agcaggaagg ataacaaagc
    13021 tatcaaagct catatctcct ccaagggctg ccttaatcca agcccagttt tcacgcgccc
    13081 aagaccaagc tgttttctga gttgcttgat gagctaggaa ttggtaatac caagcagaca
    13141 agtcctgtgg tttgaccaca aatttgtcct tccaagaagt aatcaagttt tggatattat
    13201 ccgcatctgt actgtatgca agagctgctg ccaactggcg tttaaagaca gcatctgttg
    13261 cgtgagtata agtatcaaga taaagtgcta acaagtcttt agtctcatga tgtttcatct
    13321 cattaatcag aacttgtgaa cgaatagctg ctgggagtcc tgcaagattc tccttgtgtg
    13381 ttgcgaagat ttggctagcg acttgactag cttctgcatc atttgagcga atcatcatcg
    13441 aaacagccag ctgacgaacc aattcatcct catctgattc tccgtcttta gcttcaaaac
    13501 caagacggtc atagttatga cgagccaatt tagcaaccag tcctttgaag gctgtttcag
    13561 catccgttcc ttcatcaata aagcgctcaa gggctgaaat cacttgagaa acagctgaaa
    13621 ccaccagata agactcttcc ttagcaagtt tatcaagaac tggaagcaag tctgcataag
    13681 aaatgtgccc tgcctcagcc aacaaacgac gttcttgaac aatttgcagt ttgcttgtgt
    13741 tatcaagtgt ctctagctca gcaagaacag cttctaacaa gtctccttga tagtcggtaa
    13801 tatagtgggc agtattttca gtgttgagac gaagagctcc ttcattttca gcaagaagag
    13861 ctgcgtagcc agggatttcg atactttcag tttcgagtgt atcaggcaag cctttccagt
    13921 tgctattgag gggcaccacc cagagacggt tcttgtcttc gttctcaccg atgaagaatt
    13981 gtttttgtga aatcttcaag acatcatttt caactttaac agtaagaact gggtaaccag
    14041 gctgttccaa ccaagaatcc atgaaggctg cgacatcacg tcctgacgct tgaccaaggg
    14101 catcccaaag gtcactacca atggtgttgc tgtattggtg tttttcaaag taggcgtgca
    14161 aacctttagc aaaatcagca tctcctagcc aacggcgaag catgtgcatg agacggcttc
    14221 ctttggcata gacgatagcg ccgtcaaaga gtgtattgat ttcatctgga tgtttaactt
    14281 cgacgtggac agactgaacg ccatcagtag cgtcacgttc aagagcaaga ggtactccac
    14341 ctgtttggaa atcttcaaag atattccagc ttggttcgat ggtatccaca cagacgtatt
    14401 ccatcatatt agcaaaactt tcattgagcc aaaggtcatc ccaccatttc atagtcacga
    14461 ggttcccaaa ccattggtga gccaattcat gggccacaac aagggcaact tgttgacggc
    14521 tagcaaatgt agagttctca tcgacaacca agtaaacttc acggtaggtc acaagacccc
    14581 agttttccat agcaccagct gagaagtcag gaagggcgat gtggagagat tgaggaattg
    14641 ggtacttaac tccatagtaa tcttcgtaaa actcgataga gcgaacagcg atatccagtg
    14701 agaaatcaag atttgaaagt ggatgtgctt tggttgagta gacacctacc agggtaccat
    14761 ttttagtttt agcggtcacc ccttgcaaat caccagcaac aaaggccaac aagtaagaag
    14821 acatgcgagg tgttgtctca aacttccaga tacctgtttc cttacggttt tcaacatcga
    14881 tttctggcat gtttgacaag gccaattcac cttctgcttg gtcaaagcga agagagagat
    14941 caaaagttgc tttggcttca ggctcatcca cacatgggaa agcttcgcgc gcaaaatggc
    15001 tctcgaactg agtagacaag acctccttct tgactccatc aactgtataa taagaagggt
    15061 aaatccctgt catgttgtct gtaattttac cagaaaaggc aagaaccaat tcaacttgac
    15121 cagcctcagc caattcgata tgaagggctt cattgtcatg gtcaactgta aatggacgag
    15181 cttgacctgc aacttctaca gaggtgattt ccaagtcttt ttggtggagg gagatgcggt
    15241 cactctgtgc ttgaccagtg atggtcactt tcccagaaaa agtcttggtc tcacgactca
    15301 aatctaaaaa taaatcataa tgttcaggaa caaattgctt aataaaatgt tcaactgctt
    15361 gcatagtttt ctcctattct aagtttaaga gctgctgctc ttcttcaaac aaacttatta
    15421 tatcatattt tgcttgagaa aaaaggattg gacagcgatt tccaaaactt tcttccttct
    15481 aatagtctac agtgggtaga ccttgcgaaa ttcttctaaa acaaccttgc tttcaggtgt
    15541 aaaagtcagc cctacttcac ccaaacagtc tgtgaaaaag tcctcatgag cctggcgcca
    15601 ataggcaagt gatttgtctc cctcaccttc cttaaaggca tgttgcgcag agacttgatt
    15661 gaagagttca acagaaacct ttgtaatttc gacaatgcag acagactgat tttgactatc
    15721 taaaatgaca tcgaaggtcc ctacttgggg aagtggttcg tcttctagta catagaggtc
    15781 ataggctgat gctgttgctg tcttttctcc tttaaacacc aaatccgcta aaaggtctgg
    15841 ttcaactcca aaagcccaag catcgatttc atctccgatc aaaggattga tttgcttgta
    15901 tttattccac atttcttgcg gtatcatggg tactcctttg taatttttta ctttcttctt
    15961 ttatgtgttt aagatgatct ggatggtcaa tctctaaatc aaaaatctct ggaatagaac
    16021 tgtagtggat aatgcacttg atacccaact gattcatttt ttgtatgaaa gaagtattca
    16081 gatagcctgc tacagcaaaa ttaatcttgt tctttcttgc tttatcctgc atatctctta
    16141 gcatatctaa cattattgga ctttccatat catgccattg actgtttctc atagtcgcaa
    16201 aaacaaagga agtcaaatca ttcattccaa ctacaatctt tgaaatgccc gtttccagta
    16261 tactagataa gtcaaaatac gctgacggta attcaatcat cgttccgact ttcccagtaa
    16321 agccatactg acgcaatact gtaatagctt gttttaattg gtcggcatca ttgacagaag
    16381 gaaagataag agatagattg gggttggttt gataaacttc tgtaacgaca tgtgcttcag
    16441 cctgaaattc atccaaacac gccagtaaac gtctggttcc tctatagcca aacaagggat
    16501 gcccttcgtc aaaaaactct ctagtcccca ctaaacaatt ggcttctgta ttcgttaatt
    16561 cagaaaaacg ataccaaact tcttcatctg agtacaggga gcagatagtc tctagataat
    16621 cttttacaaa ttgctgacaa cttgctaata tgatgttttg attaagctct ctcaacaaat
    16681 attccccacg aatcatgccg acgtggtgaa atagttgagg ataaattttt tcaagaattt
    16741 tttcgccact aagggcaagt tgatttctca tagccattca cctcgtctta aaagatacaa
    16801 tatcatatat aattatatca aaatttcctc tagttcaaaa gcttcataag gttcagataa
    16861 ctcatatcct aaaaattctg ctactttttt ggaagcctca ttatgagcat cccaaagtgg
    16921 aaacatatct ctatttaaac tctctagaat cattgcagca ccaagctttt tagcaaatcc
    16981 atttccttgt tcgtttggtc tagttgcaac ttccacttca actgctttac ggtaaactaa
    17041 ccctgaggaa atcccagcaa tcagttcatt atttttaaga atcacaaagc caaatccacc
    17101 ttttaaaaca aaatcctgat aggactcaaa atccccctgt aaatcctgtg accattcttc
    17161 cgtagaaaag cagttataaa tatgattatc aataggcaca atattgtaac cttcctctaa
    17221 atgagtaact agattattta aaaattcaac ttgaaaattt gccttatctt taaaagaata
    17281 gcgagtaaaa gaatttagcc ccacttttcg atgcagaaaa tcttgccaat tagtattttc
    17341 tgaaataata atcttataat ctaaaccata ttttctaaca aaatcttccc aaaatctgga
    17401 atccaactcc cctgctaggt atagaaaatt cccaacatca taaaagcttg ttgtcctatc
    17461 attgtttcgg tagacagttc caatttgaga tttaagacca tagagaacca tatttttctt
    17521 ccatgtttta aatagttcca ttatccctct acttcacctt ccaattcatg taagaagtct
    17581 tgtccagttc tggcaatcct aataattcag acttaacctt caagactaat ggcgatgcat
    17641 tttcttctgt aatctcttga atatccatcc aaatatatcc aagtgaatca ttcgcaccat
    17701 cagacacagc ttccgaaatc gtaacttgag gtgcactctc attcatttca acatcataca
    17761 aggctatgac atggtgaacc ataaaatttt ttaactcttc cctgacgaaa acatcgtaga
    17821 ttcgaggatt agagtagctt ctaacagtaa atcccgtctc ttccataact tctctagtca
    17881 gcgtttccgt cagtccttca ccaagttgct gactgcctcc aggtagatca taccgatgtt
    17941 gataagggcc tctcgttttt tcaatgcaaa gtaactttcc attttcaaag caaacacagt
    18001 agaccccaaa gtgatttttg atttccatcc aactcctcct acttcaaaga ccagccacca
    18061 tctattgtca gaatttgtcc ctgcatggca gatgcctttc cactggccaa aaagagactg
    18121 acttctgcca cttcctctgg ttcaatccag cgcttgattg gtgtttcact agccacccag
    18181 tcagctaagc cacctgtctc aaaatccgca gcggtcatag ctgtcttgac tgctcctgga
    18241 gcgataccaa agacctgaat cccagcttca gcatagtcta gagccaactg cttggtgaag
    18301 ccagccaagg catgcttgga tgaagtatag gcgtgaccac ctccacctgc taggctagaa
    18361 gcaatggaac acatattgat gatgattccc tttttatttt ccagcatttg tgtcaaataa
    18421 taccgagtca actctactgg aataatgtag ttgatttcaa aaatctcttg aatgtcctgc
    18481 gccgtttgtt ccaacagtgg tttgtaatca tccaaaactc cggcagtatt acacaaaaca
    18541 tccacctgag ggcaccagtc aaaaataggt tccaagtcca aggtcaaatc tctctgtaaa
    18601 aagtgaaaat caccctctaa gagtggcttt tcaccttggt caactccata aacttgatag
    18661 cccttctcta aaaagaggcg agcttgagcc aatccgatcc ctgaactcac tcctgtaatg
    18721 agtacacgtt tagtcatgca cttctaccca atccgttgcc aaaacatcac aaactgtcgg
    18781 gctccacatg gaaaaacctt ctccttctcc agaaacgttg attaggaaat aaggtgtcat
    18841 ttcaagtgca agcccatttt gctcgatggt atcaaagagt tggacatagt tttccgcacc
    18901 tccccaacca gttcgtacat attttctctt agcctttaac ccaggcagga tctcttcaaa
    18961 tgtcatgttt ttctccttta attctacatt cttcatttaa ttatagcaaa aaaccacttt
    19021 atacggcttt ttgactgtga gttattcaaa cctgctacta cttacggcaa attattccct
    19081 gcagcaagat aaatttcata ccattctttt cttgttaagc taaagtttgc cgctcggcta
    19141 acttctctca agtgcttagg atttgttgta cctacgactg cctgcatttt tgctggataa
    19201 cgcaatatcc aagaaatggc aatagttgaa gaggttactc catatttaat agctaaacga
    19261 tcaagtactt gatttaaagc ttgaaatttc tcatttccaa caaagttccc tttaaaatac
    19321 ccgaattgca agacagacca tgcttgaatg accacatcgt gtaatttgca atattcaaaa
    19381 atgctgccat ctcgcatagc tgcttgacta tcttccatat taacatgaaa agctgattca
    19441 aatcctggag taaaagccgc actcaattgt agctgattaa cagctaacgg ctgcttgaca
    19501 tcttttttaa gcaactccat catcatagga ttttgattag aaactccaaa atctcgaact
    19561 ttaccttgtt tataaaggag atcaaaggct tctgctactt ggtcagattc catcaaagca
    19621 tctggtcgat gaaggagcaa gctatctaga tgatcaatct tcaatctttg caaaataccg
    19681 tctactgatt ttataatata gtccttagaa aaatcaaaat aggtaaattc ttcaatgcga
    19741 atgccacatt tggactgaat ccacatcttt tctcttaaat ctggacgatt ttttaggaca
    19801 agacctaaca gttcttcaca acgaccacga ccataaatat cagccaagtc gaaggcattg
    19861 attccaacag aaagtgctgt ttctacaagc tcttcaactt cttttacaga cttatctttt
    19921 attctcatca ttccgagaac aatttctgat aattctttgt catcttgacc aagagttatg
    19981 tatctcatca aatttttctc ctttaatttc taacattctt cccttcatta taacaaaaaa
    20041 ccgctttgca acggcttttt gactatactt cactccattt tatcttctta aacccacgga
    20101 acaagacaaa gattccaata aagaggacag ctaaaggaat aacttttgta aggaaaacat
    20161 ttgaaattcc catctactca taataacgga gcagagaacc caccacaaga tgggcaataa
    20221 tcatactgac aaatggacga aagaccgctt ctttccaatt ccaaataccg ataactagcg
    20281 aaatcgtaaa gacagacaaa ctatcccagg gagccggaat ataaaaggct ccttcttgta
    20341 tgaagcttgc cattcctaca tatcctaaaa caactagaag aactatagtc ccaacaacaa
    20401 tgtaagtgcc aattttcatt ttaggagaat cttggactaa acttcttcgt aaaattgtgg
    20461 ccacaagtcc aaatccaatc agaaaaataa gaagttgccc taaaaatgtg agcaaattga
    20521 ctgttaagag aggaccttta gaaaaatcac ttagtagttg ataataacgt aataccgcca
    20581 ggacaagaat tggcgtcaaa agggactctt tgatagaact gcgaggtgct cccttgagaa
    20641 tctctttcat tattttttta ggattcttac ctagataatc ctctgcactc atgccatctc
    20701 gttctgcttc tgagaaatct agcatcatca aatagatctg ctctctgaga tagtcttcat
    20761 catagagaaa tccagcaaga ttaaaacttt cccacaactc ctcaaaatac ttttgattct
    20821 cctcagaaaa ctcatgtagc aaagcgcttg tttcttcgta atacttcatt ttcttcatgg
    20881 tttaaccccc attcttaatc ccttctactt tttgactcaa atcgtcccat tgttgccaaa
    20941 agactgagac acgctcttct ccttctttca ttaatgaaaa atacttccga tctggaccat
    21001 ctggcgacgg gcgcatgtcg cctcttatcc attgattttt ttctaacttt tgcaacaaag
    21061 gataaatagt tcctggaacg atagtatcaa atccagcctc tcgcaaagtc tgaaccaact
    21121 cataaccata ccgctctttt tgaccaatca tatccaagac acaaccttca agaacacctt
    21181 ttaatagctg agtttctttc atcacttctc ccttctaatc tattttgtaa tacctactag
    21241 taacttcacc tatagtatat cacttctaca ctagtttgta aagcataata gttaatactc
    21301 ttcgaaaatc tcttcaaacc acgtcagcgt cgccctaccg tatgtatggt t
//
LOCUS       DAVLHM010000037        20586 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLHM010000037 DAVLHM010000000
VERSION     DAVLHM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.037"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            87..1862
                     /locus_tag="VXE45_001555"
     CDS             87..1862
                     /locus_tag="VXE45_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEV0789570.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDDKTLKFYFYGQEKEEIFNYQEEHDLFIYYLDPITGIEIP
                     LENTIKIVETEEETDLIIKIGDYVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFK
                     FNYTRPDLLSKAIKCTQVFQELGKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLL
                     KISNFMKKMGIQKDVDLSCFDKQSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANI
                     HIITLYSFLSDKNGTMIDIFTETPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKI
                     DSVIASYQRLVDNKLKYEGADRTILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYS
                     KNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYELCFGSSVLLKSKPQADLF
                     WNKLDNETKERYKDFPIYTLYMKLS"
     gene            complement(2073..2879)
                     /gene="yidA"
                     /locus_tag="VXE45_001556"
     CDS             complement(2073..2879)
                     /gene="yidA"
                     /locus_tag="VXE45_001556"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0789571.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMADKEIVKCMFIDEPE
                     ILDATIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(2892..4196)
                     /locus_tag="VXE45_001557"
     CDS             complement(2892..4196)
                     /locus_tag="VXE45_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0789572.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            4268..4645
                     /locus_tag="VXE45_001558"
     CDS             4268..4645
                     /locus_tag="VXE45_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0789573.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            4735..5067
                     /locus_tag="VXE45_001559"
     CDS             4735..5067
                     /locus_tag="VXE45_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0789574.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            5079..6650
                     /gene="ffh"
                     /locus_tag="VXE45_001560"
     CDS             5079..6650
                     /gene="ffh"
                     /locus_tag="VXE45_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0789575.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(6845..8128)
                     /locus_tag="VXE45_001561"
     CDS             complement(6845..8128)
                     /locus_tag="VXE45_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0789576.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTSGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(8382..9095)
                     /gene="rsmG"
                     /locus_tag="VXE45_001562"
     CDS             complement(8382..9095)
                     /gene="rsmG"
                     /locus_tag="VXE45_001562"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0789577.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            9189..9749
                     /locus_tag="VXE45_001563"
     CDS             9189..9749
                     /locus_tag="VXE45_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0789578.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            9751..10650
                     /gene="htpX"
                     /locus_tag="VXE45_001564"
     CDS             9751..10650
                     /gene="htpX"
                     /locus_tag="VXE45_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0789579.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10799..12358)
                     /locus_tag="VXE45_001565"
     CDS             complement(10799..12358)
                     /locus_tag="VXE45_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0789580.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(12597..12914)
                     /locus_tag="VXE45_001566"
     CDS             complement(12597..12914)
                     /locus_tag="VXE45_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0789581.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            13084..13626
                     /locus_tag="VXE45_001567"
     CDS             13084..13626
                     /locus_tag="VXE45_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0789582.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            13626..14255
                     /gene="nth"
                     /locus_tag="VXE45_001568"
     CDS             13626..14255
                     /gene="nth"
                     /locus_tag="VXE45_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0789583.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            14466..14987
                     /gene="pyrR"
                     /locus_tag="VXE45_001569"
     CDS             14466..14987
                     /gene="pyrR"
                     /locus_tag="VXE45_001569"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0789584.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            15006..15929
                     /locus_tag="VXE45_001570"
     CDS             15006..15929
                     /locus_tag="VXE45_001570"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0789585.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            15979..17058
                     /gene="carA"
                     /locus_tag="VXE45_001571"
     CDS             15979..17058
                     /gene="carA"
                     /locus_tag="VXE45_001571"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0789586.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            17371..20547
                     /gene="carB"
                     /locus_tag="VXE45_001572"
     CDS             17371..20547
                     /gene="carB"
                     /locus_tag="VXE45_001572"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0789587.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         6162 a         3840 c         4515 g         6069 t
ORIGIN      
        1 tttaattgta gtttattgaa tgctatgtat ttttatttct taatgctata atataaagta
       61 tatagagtta ttttagaggt gcagatttgg ccaataatag gaaaactgag acattaggtg
      121 tttcatatct ttcaacattt atagataagc atgagttact tcaatcttat tttgaaagta
      181 atgataaaac tccagtatgg gatggagaaa ttcatgttct taaatcaccg agtgagaaga
      241 aagacgaaat attaggtaaa gtacctgttc agattaaaac tactagacag aaaaaagatg
      301 tgttaaaatc cttctcatta gatactagag atttagaact atataaacca aatggtggag
      361 tagttttatt tgtagtttgg ttgaatgagg ataatggttt aagagatatt tactataagt
      421 cattacctcc tctttctata aagaatttgc tcaaaaagag taaactaaaa aataaatcta
      481 caaataggaa gaaactttcc atagagattt ttaaactgga tgagaaaaaa atgtatccaa
      541 tgttagtgga tttcataaac aatagtcaga agcagtatag tttcataaat gtcgaaggta
      601 tttcagttga ggacattcct gatgataaaa ctctaaagtt ctacttctat ggtcaggaaa
      661 aagaagaaat ttttaactat caggaagaac atgatctctt tatttattat ttagatccta
      721 taactggcat agaaatacct cttgaaaaca caataaagat tgtagaaact gaagaagaaa
      781 cggatttaat tataaaaata ggcgattatg tttttcaaga cgtaaaaaga catcgttttc
      841 ctgatgggag tgtacagctt cattttggtg aaagctttac aatgtctttt gacataaaga
      901 agaaacaatt caaatttaac tatactaggc cggatttgct gtcaaaagct ataaagtgta
      961 ctcaggtatt tcaagagcta ggaaaaatcg gatattttac ccttaatggt aataaaatag
     1021 agttagatga acggtcaata aaggatattt cttcacttga tttagaggct gatataaagg
     1081 gattgttaaa aatttctaac tttatgaaaa aaatgggtat acaaaaagat gttgatttat
     1141 cttgctttga taaacaatct caaagaaatc taaatattct ttattcaggt cttgtcttaa
     1201 aaaagaaagt tgctttaaat tataatgaat cgaaattact tcacctaaat attgctaaca
     1261 tccacattat aactttatat agttttttgt cagataaaaa tggaactatg atagacattt
     1321 ttactgaaac tccttggtgc cgggaaggag aaactgaaga tgaagattat ttagacattt
     1381 caatttttga agtatttgaa ccaaacgatt ggctaaaaat tgataattgt aaaattgatt
     1441 cagttattgc ctcgtatcaa agattggtag ataataagct gaaatatgaa ggcgctgacc
     1501 gtactatttt aaaaatagtt atcgctgcag acatggcaga agataagact aaaagagagt
     1561 tgttacttaa ttgggcgcaa tgtctttctg actggaactt aaaatactca aaaaattgtg
     1621 agatggctat aataaatgac cttcaaataa aatctagagt tcgtaaatta aacagcaaag
     1681 aaacagagac actaactaat attttagtaa atagtaatga taactatgaa ctttgtttcg
     1741 gttcatcagt gctattaaaa tcgaaaccac aagctgattt gttttggaat aaactggata
     1801 atgagacaaa agaaagatat aaggactttc ctatttatac tttgtatatg aaattatcgt
     1861 aaaattaaaa gagattataa agagataaca tatagaaata gagagtgatt tattacaatt
     1921 cagtaccaca aattaagaaa gcaatgccta ttttttgtac tctcaagatt taagtaactg
     1981 tacaactgca attaaattta ttaatttact ctcattgtga tatattcata caaaaaccgc
     2041 tcagctgagc ggttttagtc tattctttcc ttttacagta cccatgttcg gatggcgtgg
     2101 gcaacgccgg attcgtcatt tgttttagtg atgtatttgg cgattttttt gatttctgga
     2161 tttccatttt ccatgacaac ggggtttcca acgacttcca gcatggcacg gtcattttct
     2221 tcgtcaccga ttgccatggt ttcatctttg gtcaatccga gtttttcagc caagtgagta
     2281 atggctgaac ccttgtctac attctttgta aggagttcga ggtagaaagg agcagatttg
     2341 ttgatggagt agcgctcgta aaattctgct ggaatttttt caatcgtagc atcgaggatt
     2401 tctggttcat cgatgaacat acatttgaca atttccttgt cagccatttc ttcaggtgta
     2461 cggtagaaga taggcatgct gacgagggtt gattcgtgca cagtgtattt tccgatattg
     2521 cgattggcag tatagatacc gtccttggta atggcgtgca tgtggacacc gagcttgcgg
     2581 ctgagaaatt ccatatctag ataatcctca taagtcaagg attcgctgat aatctcatgt
     2641 cctgtagcag tttcttggac aagggcaccg ttgaaggtta ccacatagtc cccctcgtct
     2701 ctcaactgca agtcgtctag aagtttggca acgcctgcga tagggcggcc agttgcaatc
     2761 acgactttga caccagcttc tttggcatct tggatggcag aaaagacttc aggagtgatt
     2821 tccttttggc tgttgactag ggttccgtca atatcgacgg cgattagttt aatactcata
     2881 aatttcctct tttagttttt atttggggta aaatgatcgt tctcaatcaa gtgtaaaaat
     2941 tgctgggtga tgcttgcgaa gatgctgttt tggtctaaca tttctttcgg gaaataaaag
     3001 cgattatctc cgtggcgact tccagcaagg gattggacga taggggacag gctagagagt
     3061 tctgccagtt ctccattttt ttgtaaaatc tcaatctgtg tccttggatt ttcagattcg
     3121 ggacggtaaa tatcataagg gaggtcaaag ttcttatgaa tggcagtata gtagtcggga
     3181 tcaaagccga tgtcctcaac caattttctc atgctagcga gttggtcttg gtcttcttgt
     3241 gaaaaggtaa tggatttaaa gaccttgcgg ttgacaaagc gatgcgataa atctgcaaga
     3301 atcttgtcag gactggtcat ccagagttgg aagtaggtat tcatcacacc atcatccaga
     3361 gccagatagt cagtcaaggt cacatttttt tcgaagaaag gcaggaggtg tggagaagtt
     3421 cgggcaaaga aatccttgtc ctcaggatag agttccttgg cgcgtttgag aagattctgt
     3481 aggagaactt ccatggcgcg tgttgcgggg tggaaataaa cctgcatgta catctggtag
     3541 cgactgagga cgtagtcttc gatggcgtgc atgccattgc gctgaaaggc gataccattt
     3601 tcgataggac gaatgactcg gaggattcga gtcaggtcaa attccccata ggatgctcct
     3661 gtaaaatagg agtcgcgcaa gagatagtcc atgcgatctg cgtcaatctg actagaaatg
     3721 agctgcacga cctgcttgtt aggataggta tggtctatga cactggcaac tttctctgga
     3781 aaatcgggcg ctacttgtag caggacttgg tgaatctctg tctcaggatt ttgaataatc
     3841 tcctgagtaa tggcttcatg gtctgtatca aagagatttt caaaagtatg ggagtaggca
     3901 ccatgcccaa ggtcgtgtag gagagcagcg gtcatggtca agagagactc ggcaggattc
     3961 cattcctcag gatatttttc ttcgaaaatc tctgtgatgc gtcgtgcaat ttcatagact
     4021 cctagacagt gagagaagcg actgtgttct ccaccgtgga aggtataact ggaagttccc
     4081 agttgtttga tccggcgcaa acgctgaaat tcttttgtat taatcaagtc atagatgatt
     4141 tgattattga catggatgta gttgtgaaca gggtcacgga atactttttc gttcatatga
     4201 ccattatagc aaaatcctgc tctttttggt aaaatagtag gacaagagac aagaaagagg
     4261 gcctgatgtg aagattcgga tgcgaaatac aattcagttt gatgagcagt tggaagtgat
     4321 tgaccagctt tatgatgtgg aagtgcatga aaaaggagat tatagctacc tgcttttcta
     4381 taatgaggaa aaggaaaaag tagtgattaa atttcatggt caagaactta tgatgagccg
     4441 attttccaat cccaagacca ttatgcgctt tttaaaggat agtgatagtt tggcctatat
     4501 tcctacccct atgggcatgc aggaatttat cattcaaacg agccgttatc aagtagatgg
     4561 gcaaaagatt gagctagctt atcaactaca aaatcaagag gggcatccct ttgccagcta
     4621 tcaattggaa attacttggg gctaggatct cgtttttctc aaatctactt tctatcttca
     4681 aggattggct ccctagtgtg gtagattagg ctattttttg gtataataaa agttatggaa
     4741 atcgaaaaaa ccaatcgtat gaatgcgctc tttgaatttt atgcggcgct tttgacagat
     4801 aagcaaatga attatatcga gctttactac gctgatgatt acagtcttgc tgagatagct
     4861 gaggagtttg gtgttagtcg tcaggctgtc tatgacaata tcaagcgaac agaaaagatt
     4921 ctggaagatt atgagatgaa attgcacatg tactcggact acattgtccg tagtcagatt
     4981 tttgaccaaa tcttggagcg ctatcccaag gatgattttc tgcaggagca gatagaaatt
     5041 ttaacaagca ttgataatag agaataagag gaagaaaaat ggcatttgaa agtttaacag
     5101 aacgtttgca gaacgtcttt aaaaatctac gtaaaaaagg aaaaatctct gaatctgatg
     5161 tccaagaggc aaccaaagaa attcgcttgg ccttgctcga ggccgacgtt gccttgcctg
     5221 ttgtaaagga ctttatcaag aaagttcgtg agcgtgcagt cgggcatgag gtcattgata
     5281 cacttaatcc tgcgcaacag attattaaaa tcgttgatga ggaactgaca gccgttttag
     5341 gttctgatac ggcagaaatt atcaagtcac ctaagattcc aaccatcatc atgatggttg
     5401 gtttacaagg ggctggtaaa acaacctttg ctggtaaatt ggccaacaaa ctcaagaaag
     5461 aagaaaatgc tcgtcctttg atgattgcgg cggatattta tcgtccagct gccattgacc
     5521 agcttaagac cttgggacaa cagattgatg tgcctgtctt tgcacttgga acagaagtac
     5581 cagctgttga gattgtacgt caaggtttgg agcaagccca aactaatcat aacgactatg
     5641 tcttgattga tactgcgggt cgtttgcaga ttgatgagct cctcatgaat gagcttcgtg
     5701 atgtgaaagc attggctcaa ccaaatgaaa tcttgcttgt cgttgatgct atgattggtc
     5761 aggaagcagc caatgttgcg cgtgagttta atgctcagtt ggaagtgact ggggtcatcc
     5821 ttaccaagat tgatggcgat actcgtggtg gtgctgctct gtctgttcgt cacattactg
     5881 gaaaaccaat caagttcact ggtacaggtg aaaagattac ggacattgaa accttccacc
     5941 cagaccgcat gtctagccgt atccttggta tgggggatat gctcactttg attgagaaag
     6001 cttctcagga atacgatgaa caaaaagccc ttgaaatggc tgagaagatg cgcgaaaaca
     6061 cctttgattt taatgatttc atcgatcaat tagatcaggt gcaaaatatg gggccgatgg
     6121 aagacttgct caagatgatt ccaggtatgg ccaacaatcc agcccttcaa aacatgaagg
     6181 tggatgaacg ccagattgct cgtaaacgtg ccattgtgtc ttcgatgaca cctgaagagc
     6241 gtgaaaaccc agatttgtta aatccaagcc gtcgccgtcg tattgctgct ggttctggaa
     6301 atacattcgt cgaagtcaat aaattcatca aggactttaa ccaggctaaa cagctcatgc
     6361 agggtgttat gtctggggat atgaataaaa tgatgaagca aatggggatt aatccaaata
     6421 accttcctaa aaatatgcca aatatgggag gaatggatat gtctgccctt gaaggaatga
     6481 tgggacaagg cggtatgcct gacttatcag ctctcggagg agcaggaatg ccagatatga
     6541 gccagatgtt tggtggcggt ttgaaaggta aaattggtga atttgccatg aaacagtcca
     6601 tgaaacgtat ggctaacaaa atgaagaaag cgaagaagaa acgcaagtaa gacaagagat
     6661 tgatgcaaat ctcatttgat gagaaaataa agtaaaaatt tctatgataa aacgtacagt
     6721 atcaaggttt tagaatatct gatattatac gttttttgat tttaataatt ttgttaagac
     6781 acttttatta tagtatacga aaaatccact cagctgtctg agtggattag gtgtatttag
     6841 actcttagtc tttattttcg tatggcaaga tcaagttcaa gatgattcct gtcatggctg
     6901 aaagggcagt acctgaaagt gtaactggac caagtttaag gatagctcct ccaagtccaa
     6961 gaaccaacat agcacttgcg atgatgaggt ttcgcatttg agcgaaatca acacgttctt
     7021 taatcaagac tttcaaacca ttgctggcga taaccccata gagaaggatt gacataccac
     7081 caagtacagc gtttggaata gttgaaatca aggcagtgaa tttaccaagg aagctgaggg
     7141 caatcgcgat gaaggcagcg ttacggataa ctgagacaga agcgatacga gtcataccga
     7201 taacccctgt attttctccg taagttgtat tggctggtcc accaaggaag gcagaaacag
     7261 aagttgcgat accgtcacca ataagagtac ggtgaagacc tggttctttt aagaattgac
     7321 ggccacagat ttgacccaaa acagtatggt ctccgatatg ttcagaaatt gttacgatag
     7381 cgattggcaa gatagcgatg gcttctggac caaagtaaag attgtactct ttaaaggcac
     7441 cacttgtgct aaatggcaag tagaaaccag gaatttcaaa ccagttagct tctaggacag
     7501 gcgtaaagtc aaccaaacca agagttagtg cgaagaggta accaccgata atggcaaaga
     7561 ggaatggaat gattcgtagg aagccttttc cttttgtatt gataaaggca gcaattagga
     7621 aagtaacaac ggctaccaga gcatttttcc aatttccgtc tgctacaaga cctgcattgg
     7681 taacagctga acctgcaagt ccaagaccga taacgatgat cataggaccg ataatgattg
     7741 gtggcaagag tttatcaatc cattttgttc ctacaaatcg gatgctggta gcaacaagga
     7801 catagaccaa accagtcaag ataacccctg tttgagcagc agatacatcc ccccccattt
     7861 ctttcatagc cagtgacata gctgtgataa aggcgaatga agaacctaga taaactggaa
     7921 ctttaaaacc agtagcaagc atgtagatga gtgttccaac acctgaagca aaaagggcaa
     7981 cagatacagg cattcccaaa atcaatggta ccaagatggt cgcaccaaac atggcgaaaa
     8041 cgtgttggaa actaaggaga attccttttc cagccgaagg acgttggtca acgtctagta
     8101 acaaatcaac agttgattct tgtttcatat aaacctcact tttgggcatc aaaaaagagc
     8161 ccattatttt acagcaatag gccctcagag taagacttct ttaaaattta gattttaaag
     8221 agttttaaat atttctgcgt cttcgtcacc tcacgggatg acattaaaaa cctttgctta
     8281 ggatagtata gcagaaaaaa atgattttgt aaatcatttt ttcccgagcc tagaaataaa
     8341 agagcgaggc tgattttgta aacatttgtt tactaaaaaa tttaaagtgg gcgtttattt
     8401 ggcataccag ccttacgtgg atatttattt ggtgtttctt ttttcttttc taccactgtg
     8461 atatagcgcg gatctctatt cggtagggcg tagctgagat tgtcttcgac cttactaaaa
     8521 aggagattga gggcattctt agcttctaat aattcctcag gcgcattgct ggccttgagt
     8581 gccaatagtt ttccaccaac cttaaggtag ggaatggtca attcagatag gacctgcata
     8641 cgggcaaccg cacgagctgt tacaaaatca tattgagcac ggaagttctt gtcttgggca
     8701 aaatcttcgg cacgtccgtg gtagaaatga actccgttca aatccagttc ttgagccaag
     8761 agttgtagga agttgatgcg cttattgagt gaatcaataa tggtcacatc taactccgga
     8821 tagagaattt tcattggtag actaggaaat cctgccccag ccccgatatc aagaagtttg
     8881 atagtttcat tgggaatcaa accttgaaga atgggtgcaa tcgaatcgta aaaatgtttg
     8941 agataaactt cttccttgtc cgtaatcgcc gtcaaattaa tcttctcatt ccactcgacc
     9001 aagagctcaa aataacgttc aaattgttct ttttgctggt ccgaaagtgg aagattctgc
     9061 tcggcaagca agttgtaaaa tgtttttggt ttcatagtta tttccttctt tagtatcatc
     9121 ttattttacc acaatcatag aaaatttgat atactggtac taatctaaaa gcagaaagga
     9181 cttatattat gacttggatt attcttggag ttatcgctct tattgttatt tttgtgattg
     9241 ttagctataa cggtttggtt aaaaatcgta tgcaaaccaa ggaggcttgg agtcagattg
     9301 atgttcagtt gaaacgtcga aatgacctct tgccgaactt gattgagact gtaaaaggtt
     9361 atgccaaata tgaaggttct acccttgaaa aggtggcaga actacgtaac caagtggcgg
     9421 cagcgacttc accagcagaa gctatgaaag ccagtgatgc cctcactcgt caggtttcag
     9481 gtatttttgc agttgcagaa agctatccag atttgaaagc tagtgctaac tttgttaaat
     9541 tgcaagagga gttgacaaac acagaaaata aaatttctta ctctcgtcaa ctctataaca
     9601 gtgttgtcag caactacaat gtaaaattag aaactttccc gagcaatatt atcgctggaa
     9661 tgtttggatt taaagcggca gatttccttc aaacacctga agaggaaaag tcggttccta
     9721 aagttgattt tagcggttta ggtgactaag atgttgtttg atcaaattgc aagcaataaa
     9781 cgaaaaacct ggattttgtt gctggtattt ttcctactct tagctcttgt tggttatgcg
     9841 gttggttatc tctttataag atctggactt ggtggtttgg ttatcgcact gattatcggc
     9901 tttatctacg ctttgtctat gatttttcaa tcgacagaga ttgtcatgtc catgaatgga
     9961 gcgcgtgagg tggatgagca aacggcacca gacctctacc atgtagtgga agatatggct
    10021 ctggtcgccc agattcctat gccccgtgtt ttcatcattg atgatccagc cttaaatgcc
    10081 tttgcgacag gttctaatcc tcaaaatgcg gctgttgctg cgacttcagg tctactagct
    10141 atcatgaatc gtgaagaact agaagctgtt atgggacatg aagtcagtca tattcgtaat
    10201 tatgatatcc gtatttcgac tattgcagtt gcccttgcta gtgctatcac catgctttct
    10261 agtatggcag gtcgtatgat gtggtggggt ggagcaggtc gcagacgaag tgatgatgac
    10321 cgagatggaa atggtcttga aatcattatg ctagtggttt ccctactagc tattgtactg
    10381 gcacctctcg ctgcaacctt ggttcagctc gctatttctc gtcagaggga atttctggca
    10441 gatgcatcta gtgtcgagct gactcgcaat ccccagggaa tgattaatgc cctagataag
    10501 ttggacaata gcaaacctat gagtcgccac gtcgatgatg ctagcagtgc tctttatatc
    10561 aatgatccca agaaaggtgg ggggttccaa aaactctttt atacccaccc acctatctca
    10621 gaacggattg aacgtttaaa acagatgtaa aatgaaggct ggaaaaaagt ctttaaaatc
    10681 tgaaaaacgc ataatatcag gtgtgaaaac ttgatattat gcgttttact atgggaagat
    10741 ttacttcttt ttctcctaaa attgtgtttt tgccccacct atctgctatg ttgcaaattt
    10801 ataaatcttc taaattaact agcttcaaac cgtgttctgt catgcgatag atgatcgagc
    10861 agatttcttt taagaaacga cggtcatgcg aaacagtgat gagaccgcct ggataggttg
    10921 caaagagttt tctgatttgg ggttgagaag tgggagaaaa gtttcgtgtg ggttcatcca
    10981 gcaggagaaa gtttggtttg cgcaggacta aatccaaaag caggagtttt ccctgttgtc
    11041 cgccagataa ggagcgaatt tgatgctgca tttctggata actgaaattg agactggcta
    11101 ggtgagattg gattttctga agttcctctt tttccccagt tttgctgata taagctattg
    11161 gtgataaatc caattgcagt tttttgtggt aatcttgtgg cataaaacca agggaaatct
    11221 ctcttttatc attcagaagt tgctttaatt tggctaacag agttgatttc ccaacaccat
    11281 ttggcccgat aataccgatt ttttcttgcc cacggacagt tagttgtagt ttttgaacca
    11341 aaactcggtc gtcaatggac aaattttctt tttccagttg gactaagact ttagaagctg
    11401 gtaatggttg gatgtctgaa aagaaaagtt ggatttgttc ctcttcaagt ggcttttgag
    11461 tcatggactg agctgtcttt tcgtagcgtt tttcttgtga gaggacagtt ttcatctttt
    11521 tagccaatag gcgaccggca gtactatctt tggtagctcg aagcgcagtt tctacatttt
    11581 gcttaactct ccgatgtttt tccatggttt tatcgtaggc tctttggttg ttagcagctt
    11641 gctgactttg tttggcaaaa ttagcctttc tctgctcact atagctatca tagtctaaat
    11701 gctctactag cgtttccgct tctttacggt gtttgaccag tcgcaagtga acaatagtgt
    11761 ctgctgtttc agaaagaaag tcttcatcat gggaaatgaa aataacggtt tgcctggtct
    11821 tttgaatctg gccttttagc caatcaactg tctcaaggtc taggtcattt gaaggttcat
    11881 ctaaaaatag aatctcaaag ggtttggcta actcatggat aagctgaatt ttcaaagctt
    11941 ctccccctga tagattgcca atcttttggt cacttgcgaa acgattgcta tcaaaatgca
    12001 attcctccgc caaacgatag aggatactgt agtctaaatc aatagaatct aaaaagaagt
    12061 agtcgtgtaa agttttcttt ttcagctcct cgggaagttt ttgaggaatg taggccagtg
    12121 actgatagtc agattggatg tttcccttga tagtgaaatc agacaaagct tcccccatta
    12181 aaattttaag taaggttgat ttgccatttc cttcttcacc aataatagca accttttccc
    12241 cgtcttggat ggtcatgctt aggtcagata caagatctcg taaatctttg ttttgtgtga
    12301 tggttagatg attgattttt atcatatgat ttccctttct agaatgttca tagtgcataa
    12361 caaaaagctc tactttacct agtagagccc aaagtctatg tcaaaaaaac tctattaaca
    12421 tgccagaaaa agagcataaa agagcacaca aaaagagaca aaaacaagat ctactaaata
    12481 aaggttcttt atttgataga cttagttgtt catgtctccc ttacctccga gtattagtat
    12541 ctttatatta tacctttaag gaaattttgt caacagaaaa ctggaaattc tatgctctaa
    12601 aatccaaaaa caggtccata gagacttagt acgtgtttga catgctcgta atggaattta
    12661 tcatagtttc gccaagcagt gcgtgcttga tcgtttagtt ttaggctacc cagtccaatc
    12721 agaagactgg tgggttggta aaatttctca agatcaatta agatactgtt gttcaacttt
    12781 tccgtttttt tgagctcttg catagtagtg tttagcagct cttgtagtcg aatatcatct
    12841 gccgtaccct gtttacagtt ttggtagctt ttatttaact tggataggag ttgaatgagt
    12901 ttcttgtctt ccatgtgagc atcctccttg atctgatgta ctctttccct atagtatagc
    12961 actaaaaaac aaaactgtca tagtaaatat gttaaaattc tgaattttaa ttacaaagtt
    13021 tggtgtgctg atttgtagcc ttttcatggt ataatcaaga gagtaaatct ttatggagga
    13081 agtatgaaat taaatattca agaaattcgt aagcagtctg aaggtttgaa ctttgaacaa
    13141 acgttagatt tagttgatga cctgcgtgca cgtaatcaag aaattttaga tgtaaaagat
    13201 atccttgcag ttgggaaagt acaatatgaa gaccgtatgt atttcttaga ttatcaacta
    13261 tcttatacca ttgttcttgc ttcgagtcgc agtatggagc cagttgagtt agttgaatct
    13321 tatccagtca cggaagtttt catggaaggc gcaactaacc atctaaatca agaaatttta
    13381 gatgatgact tggtcttgcc catcgaaaat gaggcgcttg accttgctga gagtgtatca
    13441 gacaatatct tgctaaacat tcctatcaag gtcttgacgg ctgaagaaga agctggtcaa
    13501 ggatttgtct caggaaatga ctggcaaatc atgacagagg aagaatacca agctcaacaa
    13561 gcagtaaaga aagaagaaaa cagtcctttt gctggcttac aaggactatt tgacggagat
    13621 gaataatggt cttgtcaaaa aaacgagcac gaaaggtgct agaagaaatc attgccctct
    13681 tcccagatgc caagcctagt cttgatttta ccaatcattt tgaactcctg gttgcggtca
    13741 tgttatcagc ccagacgaca gatgcagcgg taaataaggc cacaccaggt ctctttgttg
    13801 cctttccaac accccaagct atgtctgtag cgacagagag tgagattgct tcacatattt
    13861 ctcgcttggg attgtatcgg aataaagcta aattccttaa aaaatgtgcc caacagttac
    13921 tagacgattt tgatggtcaa gtccctcaga cacgtgaaga attggagagt ttggcaggtg
    13981 ttggtcgcaa gacagccaat gttgtcatga gtgtaggatt tgggattcca gcctttgcag
    14041 ttgatactca tgtggagcgt atttgcaaac accacgatat tgtcaaaaaa tcagcgacgc
    14101 cacttgaggt ggaaaagcgg gtcatggata tcttgccgcc tgagcagtgg ttagctgccc
    14161 atcaggccat gatttatttt ggaagagcca tttgccatcc aaaaaatcca gagtgtgacc
    14221 agtacccaca attatatgat tttagcaatt tgtaagatgc tacattgaaa ctttttgctt
    14281 gattttaagc atgctttgtg ctatagtaaa tgataactaa atattccttt aaacctgtcc
    14341 cgtgaggcag gcaaggagcg cgataaagta gaagggtgaa gtctatactg tgtgcagtag
    14401 ggctcgcttg gctataaatt tcaagtctcc ttgtttaagg agacttttct ttttggaggt
    14461 ttgtcatgaa aacaaaagaa gttgtagacg aattgaccgt caaacgagcg attacgcgta
    14521 ttacttatga gattatcgaa cgcaacaaag atttgaataa gatcgtcttg gctggtatta
    14581 aaactcgtgg tgtctttatt gcccaccgaa tccaagaacg tttgaagcag ttagaaaatc
    14641 tttcagttcc tgttgtggaa ttggatacta aacctttccg tgatgatgtt aaaagtggag
    14701 aagatacttc tttggtttct gtcgatgtga cagaccgcga agttatcttg gtggatgatg
    14761 tgctctatac aggtcgtacc atccgtgctg ctattgataa tattgtcggt catggtcgtc
    14821 ctgcgcgtgt gagtttagca gttctagtcg atcgtggaca tagagaattg ccaatccgtc
    14881 cagattacgt tggaaaaaat atcccaacca gtcgttctga agaaatcatc gtagagatga
    14941 cagaacttga tgaccaagac agagttctga ttactgaaga agcttagaaa gttaaaggag
    15001 tagccatgtc agaaaatcaa caagcattga accatgtggt gtccatggaa gacctcactg
    15061 tcgatcaagt aatgaaattg atcaagcgag gaattgagtt taaaaatgga gcccagcttc
    15121 cctatgaaga ccatccgatt gtttccaatc tcttctttga ggattctaca cggacacata
    15181 agtcctttga agtcgcagag attaaacttg gattggaacg acttgacttt gatgtgaaga
    15241 ctagttcggt taataagggt gagacacttt atgacaccat tttgactctg tctgctttag
    15301 gagtggatgt ctgtgtgatt cgccatccag aggtcgacta ctatagagaa ttgattgcta
    15361 gtccaacgat tacgacttcc atcatcaatg gtggagatgg ttcgggccaa caccctagcc
    15421 agagcttgct tgatttgatg accatttatg aggaatttgg ccactttgag ggtcttaaag
    15481 ttgctattgc aggtgacttg gaccactcac gcgttgccaa atccaatatg cagattttga
    15541 aacgcttggg atctgaactc tttttcgctg gacctgagga atggagaagt caagagtttg
    15601 cagactatgg acagtttgta accattgatg aaatcattga tcaggttgat gtcatgatgt
    15661 ttctccgtgt gcaacacgaa cgccatgata gtggagctgt attttcaaaa gaagactacc
    15721 atgcccaaca tggcttgact caagaacgtt acgatcgttt gaaagaaaca gcaatcctca
    15781 tgcacccagc tccaatcaat cgtgatgtag aaatagcaga ccacttggtt gaagcaccaa
    15841 aatcacggat tgtccaacaa atgaccaatg gtgtctttgt tcgaatggca atcttagaat
    15901 ccgtactagc gagtagaaac gccaactaaa acacaagacg ttaaaagacg ccagtgagcg
    15961 tccacgagag gtgaaaatat gacaaaaaga attctagtat tagaagatgg cacagttttt
    16021 gaaggcaagg ccttcggagc agatattgat gtaacaggcg aaatcgtctt taatacaggg
    16081 atgaccggct accaagaatc cattacagac cagtcttata atggacaaat cttgaccttt
    16141 acttatcctt tggtaggaaa ttatggtatt aatcgtgatg attatgaatc cattattcca
    16201 acttgtaagg gagtcgttgt ttttgaagaa gcgcgtagag ctagcaactg gcgcaaccaa
    16261 atgaccttgg atgaattttt gaaagccaag aaaattccag ggatttcagg aattgatacg
    16321 cgtgctctta ccaagattat ccgtaagcat ggtactatgc gtgcaacctt gacccatgtt
    16381 ggggacagta tggaccatgt gacggaccag ctccaagcaa cagttttacc gacagacaat
    16441 atcaaacagg tttctactaa aacgtcttat ccagctccag gagttggttt gagcgtggtg
    16501 ctagtggact ttggtctcaa gcactcaatc ctacgtgaac tttctaaacg caactgtaac
    16561 gtgacagttg ttccttattc gacaacggct gaagaaattc tccatctcaa tcctgacgga
    16621 gttatgttgt caaatggtcc aggtaaccca gaagacgttc cacaagcact cgacatgatt
    16681 cgcggtgtac aaggaaaaat tccaatcttt ggtatttgta tgggacacca actctttgca
    16741 atggcaaacg gggctaagac ctataagatg aagtttggcc accgtggatt caaccatgcg
    16801 gtacgtgaaa tcgcaacagg acgagtagac ttcaccagcc agaaccatgg ttatgcagtc
    16861 agccgcgagg atttgccaga gcacttgatt attacccacg aagaaatcaa tgacaagtca
    16921 gtggaaggtg tgcgccacag ataccaacct gctttctctg ttcaatacca cccagatgca
    16981 gctcctgggc cacacgacgc tagctaccta tttgacgagt ttatcgagat gatggaagtt
    17041 tttaaacaat caaactaaga acgagtaaaa gctcgtcgga gaatttatgt aactgaacac
    17101 ggacggaaag ctcagaatgt agagaaacca acttggattg tcaatccttc cttgatttcc
    17161 taaaattcaa tcgctttcta ttcgtccttt gtatcttatt taatgtcgcc ctgagaggcg
    17221 acgaatagaa aggagaaggg agctccgtat ttgctgaact gaatacgggc tacggacggt
    17281 gctaaaaaga tagttattcc tagaactgac agttcttcgt cataactcct attttagctt
    17341 tgtccgcttg acacccttaa tatcttatat atgcctaaac gtactgatat tcaaaaaatt
    17401 atggtgattg gttctggtcc gattattatt ggtcaggctg ctgagtttga ctacgctggg
    17461 actcaggctt gcttgtcgtt gaaagaggaa ggttatgagg ttgttttggt taactcaaat
    17521 cctgcaacca tcatgacgga caaggaaatt gctgacaagg tttacattga accgattaca
    17581 cttgagtttg tgacacgtat tcttcgtaag gaaggtccag atgccttgct accaacactc
    17641 ggtggtcaga caggtctcaa catggccatg gaattatcta aaaatggtat cctagacgag
    17701 cttggcgttg aacttctggg taccaaatta tctgccattg accaagcgga ggaccgtgat
    17761 ctctttaaac aattgatgga agagcttgaa caacccattc cagaatctga aattgttaac
    17821 acagtagaag aagcagttgc ctttgcagcg acaattggct acccagtcat cgttcgtcca
    17881 gcctttaccc ttggtggtac tggtggtggt atgtgtgcca acgagaaaga attgcgtgaa
    17941 atcactgaaa atggtttgaa attgtcacct gttacccaat gtttgattga gcgttcgatt
    18001 gccggtttca aggaaattga atacgaagtg atgcgtgact cagctgacaa tgccttggtt
    18061 gtttgtaaca tggaaaactt tgacccagtt gggattcaca caggggattc cattgtattt
    18121 gcccctgcgc aaaccatgtc agactatgaa aaccaaatgc ttcgtgatgc gagcttgagc
    18181 attattcgtg ccctcaagat tgaaggtgga tgtaatgttc agctagctct tgatcctaac
    18241 agcttcaagt attatgttat cgaagtaaac cctcgtgtat cacgttcgtc agcccttgct
    18301 tctaaagcga caggatatcc gattgctaag ttggctgcca agattgcagt aggtttgacc
    18361 ttggatgagg ttataaaccc agttacaggt tcaacctatg ccatgtttga accagccctt
    18421 gactacgtag ttgctaagat tccacgtttc ccatttgaca agtttgaaaa gggtgaacgc
    18481 cgtctcggta cacaaatgaa ggcgactgga gaagtcatgg caatcggtcg taacatcgag
    18541 gaatctcttc tcaaggcctg ccgctccctt gaaattgggg tgcaccacaa tgaaatacct
    18601 gaacttgcag cagtttctga tgataccttg attgaaaagg ttgtcaaagc ccaagatgac
    18661 cgtctcttct acgtatcaga agccattcgt cgtggctaca cacctgaaga aattgcagag
    18721 cttacaaaaa ttgatatctt ctatcttgat aaactcttgc atatctttga aattgagcaa
    18781 gaattgggtg ctcatccaca agatctagaa gttttgaaaa cagccaaact taatggtttt
    18841 tcagaccgta agattgctga actctgggga acgactgatg ataaagttcg ccaacttcgc
    18901 ttggaaaaca agattgttcc agtttataag atggtagaca cttgtgcggc agagttcgat
    18961 tccgaaacgc catatttcta ttcaacctat ggttgggaaa atgaatctat caaatctgat
    19021 aaagaatctg tacttgtcct aggttcaggt ccaatccgta tcggtcaagg ggttgagttt
    19081 gactacgcaa ccgttcactc tgttaaggct atccaggcag ctggttatga agctatcatc
    19141 atgaactcaa acccagagac cgtttcaaca gacttctctg tatcagataa gctttacttt
    19201 gagccattga cattcgaaga tgttatgaac gtcattgact tggaacaacc aaagggagtt
    19261 atcgttcagt tcggtggtca aacagccatc aaccttgcag agccattggc aaaagcaggt
    19321 gtgaccatcc ttggtacaca ggttgctgac ctagaccgtg ccgaagaccg tgacctcttc
    19381 gagcaagctc tcaaagaatt ggatattcca cagccaccag gacaaacggc taccaatgaa
    19441 gaagaagcag ctcttgcagc tcgtaagatt ggcttcccag ttcttgtccg cccatcttat
    19501 gtacttggtg gacgtgccat ggaaatcgtt gaaaacgaag aagaccttcg ttcttacatg
    19561 cgaactgctg ttaaggctag tccagaccat ccagttcttg tcgactctta tatcgttggg
    19621 caagagtgcg aagttgatgc catttcagat ggtaaaaatg tactcattcc tggtatcatg
    19681 gagcatatcg aacgtgctgg tgtccactca ggtgactcaa tggctgttta cccaccacaa
    19741 accttgtcgc aaaaggttca ggagaccatc gcagactaca ccaaacgctt agcaatcggt
    19801 cttcactgcc ttggaatgat gaacatccag tttgttatca aggatgaaaa agtctacgtt
    19861 attgaggtca atccacgtgc cagccgtacc gttccattcc tatctaaggt aaccaatatt
    19921 cctatggctc aagtagcgac caagctcatt cttggtcaaa gtttatcaga acttggctac
    19981 caaaatggac tttaccctga aagcacccgt gttcatatca aggcacctgt cttctccttt
    20041 accaaactag ctaaggtaga cagcttgctc ggtcctgaaa tgaagtcaac aggtgaagtt
    20101 atgggttctg atgctacttt ggaaaaagct ctctataaag cctttgaagc ttcttatcta
    20161 cacttgccaa cttttggtaa tgtcgtcttt accatcgctg atgatgccaa agaagaagcc
    20221 ttgaacttgg ctcgtcgttt ccaaaacatt ggttatggaa tccttgcgac agaagggaca
    20281 gcagccttct ttgctagtca tggcttgcaa gcccaacctg ttggtaagat tggtgatgac
    20341 gataaggata tcccaagttt tgtacgcaaa ggaagaattc aagctatcat taacacagta
    20401 ggaacaaaac gaactgctga cgaagatggt gagcaaattc gtcgttcagc cattgaacac
    20461 ggggtgcccc tcttcacagc gctagataca gctaatgcca tgcttaaggt acttgaaagt
    20521 cgtagctttg ttacagaagc gatttaaata gaaaaataag atatagcaga ctgaatttag
    20581 aacagt
//
LOCUS       DAVLHM010000038        19741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLHM010000038 DAVLHM010000000
VERSION     DAVLHM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.038"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..747
                     /locus_tag="VXE45_001573"
                     /pseudo
     CDS             1..747
                     /locus_tag="VXE45_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(811..1893)
                     /locus_tag="VXE45_001574"
     CDS             complement(811..1893)
                     /locus_tag="VXE45_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0789588.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1890..2867)
                     /locus_tag="VXE45_001575"
     CDS             complement(1890..2867)
                     /locus_tag="VXE45_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0789589.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            3082..3459
                     /locus_tag="VXE45_001576"
     CDS             3082..3459
                     /locus_tag="VXE45_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0789590.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            3694..5085
                     /locus_tag="VXE45_001577"
     CDS             3694..5085
                     /locus_tag="VXE45_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0789591.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5199..6041
                     /locus_tag="VXE45_001578"
     CDS             5199..6041
                     /locus_tag="VXE45_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0789592.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            6314..7075
                     /locus_tag="VXE45_001579"
     CDS             6314..7075
                     /locus_tag="VXE45_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0789593.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            7268..8185
                     /gene="glyQ"
                     /locus_tag="VXE45_001580"
     CDS             7268..8185
                     /gene="glyQ"
                     /locus_tag="VXE45_001580"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0789594.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            8397..10433
                     /locus_tag="VXE45_001581"
     CDS             8397..10433
                     /locus_tag="VXE45_001581"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0789595.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            10475..10732
                     /locus_tag="VXE45_001582"
     CDS             10475..10732
                     /locus_tag="VXE45_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0789596.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10955..12199)
                     /locus_tag="VXE45_001583"
     CDS             complement(10955..12199)
                     /locus_tag="VXE45_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0789597.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12218..12823)
                     /locus_tag="VXE45_001584"
     CDS             complement(12218..12823)
                     /locus_tag="VXE45_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0789598.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(12883..13806)
                     /locus_tag="VXE45_001585"
     CDS             complement(12883..13806)
                     /locus_tag="VXE45_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0789599.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14100..15479
                     /locus_tag="VXE45_001586"
     CDS             14100..15479
                     /locus_tag="VXE45_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0789600.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            15631..16506
                     /gene="pdxS"
                     /locus_tag="VXE45_001587"
     CDS             15631..16506
                     /gene="pdxS"
                     /locus_tag="VXE45_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0789601.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            16507..17091
                     /gene="pdxT"
                     /locus_tag="VXE45_001588"
     CDS             16507..17091
                     /gene="pdxT"
                     /locus_tag="VXE45_001588"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0789602.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
     gene            17648..18379
                     /locus_tag="VXE45_001589"
     CDS             17648..18379
                     /locus_tag="VXE45_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789603.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            18397..19713
                     /locus_tag="VXE45_001590"
     CDS             18397..19713
                     /locus_tag="VXE45_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0789604.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVGTSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLSIFIVPTI
                     VGIGAYFYSSRILKISSILKPKKKKRKVTVTGFVNISVRLFLWLLCIGSIVSAGFIRN
                     KEIIEKQSSIILFLLIIHILIIQSLSPSIQMFLIKFLMRIFPTENYVINTGFWNLLSN
                     PSYLKSIQTSMSMGVTLISGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIIT
                     SSISLTILSSNKDIEDIKQLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILI
                     LVSIIGQFLGRSLVDISGFWQPSLIVISLLVIFYSITKGFYLFQDR"
BASE COUNT         6094 a         3511 c         4198 g         5938 t
ORIGIN      
        1 ggctacagag gcaggagaat ttgttacaat accttatttc aggcttatat cgttcctaca
       61 cacgtgatgc cttctatcaa ctgttgaagc accatggttg gcgaaatatt atgccacgtc
      121 cagaacatcc taggaaagca gacgctcaaa ccattgtcgc gtctaaaaat aaaatctcaa
      181 ttcaagaaga caagaaagcg ctttaaaacc agtagacctt ttcataaggt tcgcttgatg
      241 taccaagatg aggctggttt cggtagaatc agtaaactgg gatcttgttg gtctccaata
      301 ggagtaggtc cacatgtcca tagtcactat atacgagaat ttcgctattg ttatggagct
      361 gttgatgccc catacaggcg aatcattttt cttaatagct ggtggatgta atactgagtg
      421 gatgaacgtc tttttagaag agctttcaca agcttatcca gatgattatt ttttactcgt
      481 tatggacaat gctatatggc ataaatcaag taccttaaag attccgacta atattgattt
      541 tacctttatt cctccataca caccagagat gaacccattg aacaagtgtg gaaagagatt
      601 cgtaaacgtg gatttaagaa taaagccttt cgaactttgg aagatgtcat gaatcaactc
      661 caagatgtca tacaaggact ggagaaggag gtgataaagt ccatcgttaa tcggagatgg
      721 aatagaatgc tttttgaaag cagatgagta taaaattgaa ttgcttataa aaaagctcca
      781 tacactggat gtgtatagag caatggggct ttatttgata tagagttctt ggttttttag
      841 gacaatttct cggatacttg caaacttttt aagttttttg atttcttctg gatgagtgac
      901 gagagtaata acatatcctt ccttgcccat acggccagta cggccagcac ggtgtgtgta
      961 ggtttcgcta tctctaggaa tatcaaagtt tacgacacat tctaggctat cgatatcaat
     1021 tccacgagcc aaaaggtcag ttgcaagaag cagggttagt tggttatctt taaacttttc
     1081 taagatgatt tttctaaatt taacattaac atcactagcg agggaaacag ccaatatatc
     1141 acgatactgt agtttttcct cggcattccc aaggtctgac aggctattga agaagactag
     1201 accacggaaa tcctctacat gagccagttt tcgcagcata tccactcgat gacgttggtc
     1261 tacctgcatg tagaaatgct ggatattgtc caatttttga tcagagagat caatagtgcg
     1321 tgtattcggc acaatctttt cttggtcaaa cttggtcgtg gcactcatgt agaccagttg
     1381 gtggtcacga ggtgcgtagt gagtgatttt ttctacaaag tgaatctgag aatcatctag
     1441 taattggtca aattcatcca ggatgatggt ttccacattc atcatcttga tttttttaag
     1501 tttaatgagt tcaaagatac ggccaggagt tccaatcaga atttctggcc cctttttaag
     1561 acgttcaatt tgtcgtttct gacttgaacc tgaaaggaag agttgagcag tcaatccgat
     1621 agcttctgcc cacgttttac atacatcaaa aatctgtcca gcaagttccg tatttggtgc
     1681 tagaatcaag agttgttggg cttttttctt ttgtagtctg agaagacttg gtaggagata
     1741 cgctagggtc ttaccagttc cggtttggct cactcctagg aggttttctc cagcaagaag
     1801 gggctcaaat agttgagttt gaatgggggt gaattcttgg aaaccgagtt ggtcactcag
     1861 ttcttgccat tcagtcggta gtttggtttt catttttctg cctcaaatct aatgccagca
     1921 gtctggcgca tggtatatag tagctcatga acagagcctg catcatacag ccaagtttgg
     1981 tagagattca gatctggttg ctggatcatg tgtgcaaatg cagcgacttc ctcagtcatc
     2041 gtatgaggag cctgttggat aggaagctgg acttgatttc cttggtggtc ggtaaaaata
     2101 gctgagcgaa tatgctcaat cgtgttgaga gtcaaggttc catctgttgt ataaatctcg
     2161 caaggaagat tggaagtgat gttttttcca gccttgatgt gaacttgata gtctgggtag
     2221 aagaggatac catctccatt taggtcaatg ctattgtcaa gctgttgagc atggtaagtc
     2281 gcgtcattag ctttttcaaa aagacgaaca gcagcataga ggggataaat ccccaaatcc
     2341 atgagggctc caccagcaaa acggtctgaa aagacatttg gtgtttgtcc agccaacaag
     2401 tcaggcatct tggaagagta tttggcatag ttgaaatctg ctcctaacac ttgcttatct
     2461 gctaaaaagt ttttgatagt agtaaaggct ttctcgtggt aattacgagc tgcttcaaag
     2521 ataaaacagt tatttttttc agctgtttga atcaaatcaa accattcttg tggttgagtg
     2581 acagctggct tttcgagaat aacatgttta ccagcagaca aggcagcttt tgcctgagca
     2641 aaatgtaagg agtttggact ggcgatatag actaaatcaa aagaagattt gaagaagact
     2701 tctaattgat cgaatagttg gatattctga tagcgagaag caaaggttgc tgcagtttct
     2761 agttttctag aatagattgc gaccagttgg tattctccac tggtatgggc tgcttctatg
     2821 aaatgatggc tgatagcgcc agttccgatg acacctaatt ttagcataaa tactcctttt
     2881 ccgattttaa atccttcttt cattataaca tagatagacg ggactatcca acagagagga
     2941 gaaaatttca aataagctat tagctttctt ttccgaataa atagatagaa gcatagaatc
     3001 tagcaaacct agatttaaaa atgtgctata atagaaggag gaaaaggagg attctcagac
     3061 atccaggtat cagcccaact aatgatttgt caatttatcc gcgatatgct ggacttgcca
     3121 gcaaaaaatg tgacgatttt ggagggaagt aacattcacg tcttgccttc catgccctac
     3181 tcagcgcaag atttctatac tagtatagac gtcttggcgg agttagataa tggaatccaa
     3241 gttatcatcg aaattcaggt tcatcatcag aattttttca tcaatcgcct atgggcttat
     3301 ctgtgcagtc aggttaatca aaacctagaa aaaattcgcc aacgtgaagg tgatacccac
     3361 cagagctaca aacaaatcgc accagtatac gctatcgcaa ttgtcgatag taattacttc
     3421 tcagatgacc tagcttttca tagttttata gtaaaatgaa atgagaacag gacaaatcga
     3481 tcaggacaat caaatcgatt tctaacaatg ttttagaagt ataggtctac tattctagct
     3541 tcaatctact agaaattcca tagatataaa actacataat ctctacagat acggatgttg
     3601 gagttgatgt aagatgcttt ggcttgctag aggaattgtg gattgccaaa ttgtatcatt
     3661 gaaattattg ctcaaatttg ttatgatata aatatgaata aaagtagact aggacgtggc
     3721 agacacggga aaacgagaca tgtattattg gctttgattg gtattttagc aatttctatt
     3781 tgcctattag gcggatttat tgcttttaag atctaccagc aaaaaagttt tgagcaaaag
     3841 attgaatcgc tcaaaaaaga gaaagatgat caattgagtg agggaaatca gaaggagcat
     3901 tttcgtcagg ggcaagccga agtgattgcc tattatcctc tccaagggga gaaagtgatt
     3961 tcctctgtta gggagttgat aaatcaagat gttaaggaca agctagaaag taaggacaat
     4021 cttgttttct actatacaga gcaagaagag tcaggtttaa agggagtcgt taatcgtaat
     4081 gtgaccaaac aaatctatga tttagttgct tttaaggttg aagagactga aaagaccagt
     4141 ctaggaaagg ttcacttaac agaagatggc caacctttta cacttgacca actgttttca
     4201 gatgctagta aggctaagga acagctgata aaagagttga cctccttcat agaggataaa
     4261 aaaatagagc aagaccagag tgagcagatt gtaaaaaact tctctgacca agacttgtct
     4321 gcatggaatt ttgattacaa ggatagtcag attatccttt atccaagtcc tgtggttgaa
     4381 aatttagaag agatagcctt gccagtatct gctttctttg atgttatcca atcttcgtac
     4441 ttactcgaaa aagatgcggc cttgtaccaa tcttactttg ataagaaata tcaaaaagtt
     4501 gtcgctctaa cctttgatga tggtccaaat ccagcaacga ccccgcaggt attagagacc
     4561 ctagctaaat atgatattaa agcgactttc tttgtgcttg ggaaaaatgt ttctgggaat
     4621 gaggacttgg tgaagaggat aaaatctgaa ggtcatgttg ttggaaacca tagttggagc
     4681 catccgattc tctcgcaact ctctcttgat gaagctaaaa agcagattac tgatactgag
     4741 gatgtgctaa ctaaagtgct gggttctagt tctaaactca tgcgtccacc ttatggtgct
     4801 attacagatg atattcgcaa tagcttggat ttgagcttta tcatgtggga tgtggatagt
     4861 ctggactgga agagtaaaaa tgaagcatct attttgacag aaattcagca tcaagtagct
     4921 aacggctcta tcgttttgat gcatgatatt cacagtccga cagtcaatgc cttgccaagg
     4981 gtcattgagt atttgaaaaa tcaaggttat acctttgtga ccataccaga gatgctcaat
     5041 actcgcctaa aagctcatga gctgtactat agtcgtgatg aataagcaag aaaaaatagg
     5101 tctgttagat atttgacaga cttatttttt acagaagata gtactactta aaaaatgttt
     5161 tatgctataa ttgatgaata aaatagaagg agaagcatat gaatacctat caattaaata
     5221 atggagtaga aattccagta ttgggatttg gaacttttaa ggctaaggat ggagaagaag
     5281 cctatcgtgc agtgttagaa gccttgaagg ctggttatcg tcatattgat acggcggcga
     5341 tttatcagaa tgaagaaagt gttggtcaag caatcaaaga tagcggagtt ccacgtgaag
     5401 aaatgttcgt aactaccaag ctttggaata gtcagcaaac ctatgagcaa actcgtcaag
     5461 ctttggaaaa atctatagaa aaactgggct tggattattt ggatttgtat ttgattcatt
     5521 ggccgaaccc aaaaccgctc agagaaaatg acgcatggaa aactcgcaat gcggaagttt
     5581 ggagagcgat ggaagacctc tatcaagaag ggaaaatccg tgctatcggc gttagcaatt
     5641 ttcttcccca tcatttggat gccttgcttg aaactgcaac tatcgttcct gcggtcaatc
     5701 aagttcgctt ggcgccaggt gtgtatcaag atcaagtcgt agcttactgt cgtgaaaagg
     5761 gaattttatt ggaagcttgg gggccttttg gtcagggaga actatttgat agcaagcaag
     5821 tgcaagaaat cgcagcaaat cacggaaaat cgattgctca gatagccttg gcctggagct
     5881 tggcagaagg atttttacca cttccaaaat ctgtcacaac ctctcgtatt caagctaatc
     5941 ttgattgctt tggaattgaa ctgagtcatg aggagagaga aaacttaaaa acgattgctg
     6001 ttcaatcggg tgctccacga gttgatgatg tggatttcta gaaaatcata aaaagaattg
     6061 tacattattc taatttttga tataatagtc agcaggaaag aaagtcttat ggcgttcttc
     6121 aagcgagctt gggatagtgg gagccaagta gggcaaaata atgagctggc gctttctgta
     6181 gtattttcaa aaacaatgaa gtaataaatt agggtggaac cgcgtttctg acgcccctag
     6241 gttaaatcaa cctaggattg tcggacgcgg ttcttttgct tattcagtct attgtgtgaa
     6301 agaaaggaga gccgtggaca acctttatct tgtaaaagac gatagtcaac tagctacatt
     6361 tcgtgatttt gtagtaagaa atactgaaaa gttgaaagat tatcaatctt ttttaaagaa
     6421 tgaacttgca gtctgtgatt taccgcaagc cgttatttgg tcagatttta atgctgctac
     6481 acagattatt agggaaagcg ctgttccagc ctatacaaat aatagacgaa tggttatggc
     6541 gcctgattta gctgtttgga aagagttgta tttgtatcaa ttgatggact acgagtgttc
     6601 tcagcaaact caagcaatag aaagtcacta tcattcttta tctgaaaatt tcctcttaca
     6661 gattgtagga catgagttag ctcattggtc ggagcatttt ttagatgatt ttgatggtta
     6721 tgactcttat atctggttcg aagaggggat ggttgaatat attagtcgca agtatttctt
     6781 gacagaagag gaatttcaag cggaaaaaat ttgtaatcaa tctctcgtag aactttttca
     6841 gaagaagtat ggttggcatt cattgaatga ttttggttct tcgacttatg ataagaacta
     6901 tgcaagtatt ttttatgaat actggcgcag ctttttgaca gtagataagt tggtagaaaa
     6961 tttaggtagt gtacaagcgg tcttagattc ttatcattta tgggcaaata cagaaaaaac
     7021 ttttcccttg ttagattggt ttgttcagca gaaattaatt gaaaaagaaa tataaaaact
     7081 aaaggagtaa acaatgtcta agaaattgac atttcactgc gtcagtggca gaaacctcct
     7141 tacagtcgga ctgccccacg ctcagcacta gagtgcctga gctagacgca gtactaactc
     7201 gtcttgcctc gtatgatcga cgaggcagac tcatgtcgca agtaatttat ataaaaagga
     7261 gtaaacaatg tctaagaaat tgactttcca ggaaatcatc cttactttgc aacaattttg
     7321 gaatgaccaa ggttgtatgc ttatgcaggc ttatgataat gaaaaaggtg cgggaacaat
     7381 gagtccttac actttccttc gtgctatcgg acctgagcca tggaatgcag cttatgtaga
     7441 gccatcacgt cgtcctgctg acggtcgtta tggggaaaac cctaaccgtc tctaccaaca
     7501 ccaccaattc caggtggtca tgaagccttc tccatcaaat atccaagaac tttaccttga
     7561 atctttggaa aaattgggaa tcaatccttt ggagcacgat attcgttttg ttgaggacaa
     7621 ctgggaaaac ccatcaactg gttcagctgg tcttggttgg gaagtttggc ttgacggaat
     7681 ggaaatcact cagttcactt atttccaaca agtcggtgga ttggcaactg gccctgtgac
     7741 tgcggaagtt acctatggtt tggagcgctt ggcttcttac attcaagaag tagactctgt
     7801 ctatgatatc gagtgggctg atggtgtaaa atacggagaa atctttatcc agcctgagta
     7861 tgagcactca aaatattcat ttgaaatttc ggaccaagaa atgttgcttg aaaactttga
     7921 taagtttgaa aaagaagctg gtcgtgcatt agaagaaggc ttggtacacc ctgcctatga
     7981 ctatgttctc aaatgttcac atacctttaa tctgcttgac gcgcgtggtg ccgtatctgt
     8041 aacagagcgt gcaggctata tcgctcgtat ccgtaacttg gcccgtgtcg tagccaaaac
     8101 ctttgtcgca gaacgcaaac gcctaggcta cccacttttg gatgaagaaa caagagctaa
     8161 actcctagca gaagacgcag aataaagaga gtgacaaatt acgaaaatgg gcgaacagag
     8221 tgagccctga gccagttgcc gcagtgatga aggtatcctt agtgaaacta aggatactag
     8281 gcaaaattgg agacttttgg ctccaatttt agcaatgaaa caacgaagtt ggttgcttgc
     8341 gtgccaatca cataaggcaa actggaaaat aaaaagatac ttttcggaga aaaaacatga
     8401 caaaaaactt attagtagaa ctcggtcttg aagaattacc agcctatgtt gtcacaccaa
     8461 gtgaaaaaca actaggcgaa aaaatggcag ccttcctcaa ggaaaaccgc ctgtcttttg
     8521 aagccattca aaccttctca acaccacgtc gtttggctgt tcgtgtgact ggtttatcag
     8581 acaaacagtc tgatttgaca gaagatttca agggaccagc aaagaaaatt gccttggata
     8641 gtgatggaaa cttcaccaaa gcagctcaag gatttgtccg tgggaaaggt ttgactgttg
     8701 aagatatcga attccgtgaa attaagggtg aagaatatgt ctatgtcact aaggaagaag
     8761 ttggccaatc agttgaagcc attgttcctg gtgttgtaga tgtcttgaag tcattgactt
     8821 tccctgtcag catgcactgg gctggaaata gctttgaata catccgccct gttcacactt
     8881 taactgttct cttggatgag caagagtttg acttggattt ccttgatatc aagggaagtc
     8941 gtgtgagccg tggccatcgt ttcttgggga aagaaaccaa aattcagtca gcattgagct
     9001 atgaagaaga ccttcgtaag cagtttgtaa tcgcagatcc atgtgaacgt gagcaaatga
     9061 ttgttgacca aatcaaggaa attgaggcaa aacatggtgt acgtatcgaa attgatgcgg
     9121 atttgctgaa tgaagtcttg aatttggttg aatacccaac tgccttcatg ggaagttttg
     9181 atgctaaata ccttgaagtt ccagaagaag tcttggtgac ttctatgaag gaacaccagc
     9241 gttactttgt tgttcgtgat caagatggaa aactcttgcc aaacttcatt tctgttcgta
     9301 acggaaacgc agagcgtttg aaaaatgtca tcaaaggaaa tgaaaaagtc ttagtagccc
     9361 gcttggaaga cggagaattc ttctggcgtg aagaccaaaa attggtgatt tcagatcttg
     9421 ttgaaaaatt aaacaatgtc accttccatg agaagattgg ttcccttcgt gaacacatga
     9481 ttcgtacggg tcaaatcact gtacttttgg cagaaaaagc tggtttgtca gtggatgaaa
     9541 cagttgacct tgctcgtgca gcagccattt acaagtttga cttgttgaca ggtatggttg
     9601 gtgaatttga cgaactccaa ggaattatgg gtgaaaaata cacccttctt gctggtgaaa
     9661 ctccagcggt ggcagctgct attcgtgaac actacatgcc tacatcagct gaaggagaac
     9721 ttccagagag caaggtcggc gcagttctag ccattgcaga caaattggat acgattttga
     9781 gtttcttctc agtaggattg attccatcag gttctaatga cccttatgcc cttcgtcgtg
     9841 caactcaagg tgtggttcgt atcttggatg cctttggttg gcacattgct atggatgagc
     9901 tgattgatag cctttatgca ttgaaatttg acagtttgac ttatgaaaat aaagcagagg
     9961 ttatggactt tatcaaggct cgtgttgata agatgatggg ctctactcca aaagatatca
    10021 aggaagcagt tcttgcaggt tcaaactttg ttgtggcaga tatgttggaa gcagcaagtg
    10081 ctctcgtaga agtaagcaag gaagaagatt ttaaaccatc tgttgaatca ctttctcgtg
    10141 cctttaacct ggctgagaag gcagaagggg ttgctacagt tgattcagca ctatttgaga
    10201 atgaccaaga aaaagctttg gcagaagcag tagaaacact cgttttatca ggacctgcaa
    10261 gtcagcaatt gaaacaactc tttgcgctta gcccagtcat tgatgctttc tttgaaaata
    10321 ctatggtaat ggctgaagat caggctgtcc gtcaaaatcg tttggcaatc ttgtcacaac
    10381 taaccaagaa agcagctaag tttgcttgtt ttaaccaaat taacactaaa taaaatttga
    10441 taaacggact ttatcttatt acaaaggaga agaaatggat ccgaaaaaaa ttgctcgtat
    10501 caatgagctt gctaaaaaga aaaaaacaga aggcttaaca ccagaagaaa aagtggaaca
    10561 agccaaacta cgtgaggagt acatcgaagg ttatcgccgc gctgttcgtc accacattga
    10621 aggaatcaaa attgtggacg aagaaggaaa cgatgttaca ccagaaaaac tacgccaagt
    10681 acaacgtgaa aaaggattac atggccgtag tcttgatgat ccaaattcat aataatactc
    10741 ttcgaaaatc aaattcaaac cacgtcagct tcaccttgcc gtacttaagt acagcctgcg
    10801 gctagcttcc tagtttgctc tttgattttc attgagtata tgtattcttt cttttaacaa
    10861 agatagatga aacgataaca aagagactag cagtttgtgt ttgctagtct tttttcgcta
    10921 aaaaaggaac cataatggtt cctaaaaact atcattagta acttgcaccg gctgtagcgt
    10981 ctgcgtcacc accgtggcct ccagcatccc ctgaatcaga agcgccagaa gtagcatcgg
    11041 cgtctccatg acctccggca gcaggagcaa atggtccgct accacccacc aaacgttgac
    11101 cagtctcttt taggtaccag tcaagccatg gttggaagtt aaagacgatt tcattgatac
    11161 cagcgtatga tccatcagga tagtacattg cttggtagtt gtgagtgttg ataacacctg
    11221 caggagaacc tggaacgatc gtacggacgt attcttggtt tccgttgcga agtgttccga
    11281 taacccactc tacgttcttc atacgtgctg gtggaagaga accatgaaca gtcgacatac
    11341 ggctacctga ttgaggtggt acacgtttag cgaacatagt gtctggatct tggtgagcgt
    11401 tgttgtagta gaggaattgg ttgttgtcgt cagcgtatgt caattcaaat ggcatagctt
    11461 tcaagaacat atcaatttgg ttaactgtta ggataccgtg gtccaatttg acataggtat
    11521 caccagaaac agcaccagtg aatgctgcaa ctttttctac ccattctgga tcgtcagggt
    11581 caacttctgt gatggttgta gcgattggtt ttccacaatc caagtcttct gattcgattg
    11641 gttttggttt tttcaatttc gaaacgactc ctacgtattt aacaaagtta tctaagcaag
    11701 tttcaaggaa tttaacagtg ccttcgttgg tgatatttcc gttgttatca aaagcttcct
    11761 tagctttacc aagaaggaat tcgttacctg gaagcgtgta ggcattaaca cctggagcat
    11821 caaggatttt acgaaggtga acttgagcac gtgatgttcc ttggtcatag tatgatgcac
    11881 ccacaatcat aacaggcttg ttttcaaatg gatgaacttc gtatgaaagc cattcaagta
    11941 cagatttgag tgaagctgag atagtgtggt tatgctcagg agtagcaatg ataacaccat
    12001 ctgcacgagt aattttgtta tataaataac gtaattggaa actttcatcc catttttcat
    12061 cttggttaaa cattggaact tcgtcaattt caagaacttc taattcaaat ttgagtttga
    12121 agtagcgacg gataaattcc aagagcttac ggttatatga ttgatcgtag tttgatccaa
    12181 caagtccaac aaatttcatt ctttttggtc tcctatctta caaattttcc cagtcaaagt
    12241 cttcagcatc tttgcgaagt aattcttgtg cattacgtaa tttttctgtg atttttacaa
    12301 agatacggaa gtcatcaaag atggcatcca atttcttgat aacatcaagg tcaaccaagt
    12361 cgccacttgg gttaaatgct tgaagagagt gtgagagcaa gaattcatct ggaagaacat
    12421 ttgccttgat ttcaggagca ttcaagattt gacgaagttg caattgggca cgagatgaac
    12481 caagcgtacc gtaagaagca cctgtaatca tgattggttt gttcaaaagt gggtaaatac
    12541 cataagataa ccaagcaaga gcgctcatca aaacagctgg aatagagtga tcatactcag
    12601 gagtaccgat aataacgcca tctgcctctt cgattttagc agcaatttcc aatatttcag
    12661 caggtacttg cttgtcagct ggtttgttga agacaggaat ggccttgatt tcaacaagtt
    12721 caatttcagc tttgtcagta aagtgttttt gcatgtattg aagcaattga cggtttgtag
    12781 aacgttttga atttgttcca acaatagcaa taagttttaa catgagattt cctttctctt
    12841 tttacataat acaattttaa aattccattg aaacagttgt ctctatagag taggaattcc
    12901 tgaagaacag cttaggtggc cttctttatc gatgaggatg acttcgatgc cctccaaact
    12961 ttcgacttgc cagaggatag aagcaggtct ttctccaaag agtcgagtcg tccagatttc
    13021 gccatcgact gatttatcag agatgattgt tagactcgct agttccgttt caacaggata
    13081 tcctgtttga ctgtcaaaaa tgtgatggta atcttgtcca tcgacggtca ggtgacgttc
    13141 ataaatgcct gaagtcacga cagatttatt gacaacaggg atggtcatta aatgatttcc
    13201 cctaggattg gctgggtctt gaatcccgat ttgccatggg ttatcccctc ttgcctgatt
    13261 ttttccaatg gtcaggatat tccctcccag attgatcaag gcagaagtca ccccctcttt
    13321 cctaagaaat tgggcaacct tatccgcact gtatcctttg gctaaacaac ctagatcgat
    13381 cttcattcct ttctgtttta aaaacacagt agaagtagaa gaatctaact cgataccatg
    13441 aggattgatt agaggcagca ccgattcaat ttcttgaggc tgggcgacct tggcatctga
    13501 aaaaccgata cgccaggttt gaattaaggg accaatgctg atattgaggt ggctagagag
    13561 cgctaggcta tgctctaacc caagtgaaat cagctcaaac aggtctggat gaaccgtgac
    13621 gggggctatt cctgcttgat aattgatttc catcaactca gattcttgac tattggcgtt
    13681 gaagcggtat tcaagttctt tgagcaagtc aaaggatttt tggagaaaga tatcggcttg
    13741 ctcatccact aatgaaatag tgatagtagt ccccattagc cgttcagaat gtgaacgaag
    13801 agtcaagcta ccaactcctt tctcttatag aaaataagtt gtaatatcaa ataatcatct
    13861 aaattgaagc ccttacattt cattttcatg ttattataat accataaagt tagaattttc
    13921 acaaacaaaa tttggaaaaa gtcaagaaat atgctcataa aattcatcag gcttgaaaac
    13981 aggataaatg gggaattatt tttgataaaa aatgctgaaa taatagtacc ccccttgtaa
    14041 acgctaacgg taaatggtat actagtaagg taaatttaga atgaaggcag gaaattttta
    14101 tgagtaaaat cgttgtagtc ggtgctaacc acgctggtac agcatgtatc aataccatgt
    14161 tggataattt tggaaatgag aacgaaattg ttgtatttga ccaaaactct aacatctctt
    14221 tcctaggatg tggaatggct ctttggattg gtgaacaaat tgacggtgct gaaggcttgt
    14281 tctattctga taaagaaaaa ttggaagcta aaggtgctaa agtttacatg aactcacctg
    14341 ttctttcaat cgactatgat aacaaagtag ttacagcgga agttgaagga aaagagcaca
    14401 aagaatcata cgaaaaattg attttcgcta caggttctac accaatcttg ccaccaatcg
    14461 aaggtgttga aattgttaaa ggaaaccgcg aatttaaagc aactcttgaa aacgtacaat
    14521 tcgtgaaatt gtaccaaaat gctgaagaag ttatcaataa actttctgac aagagccaac
    14581 acctcgaccg tatcgccgtt gttggtggtg gttacatcgg tgttgaactt gctgaagcct
    14641 ttgaacgtct tggaaaagaa gttgtccttg ttgatatcgt tgatactgtc ttgaacggtt
    14701 actatgacaa agacttcaca caaatgatgg cgaagaactt ggaagatcac aacatccgct
    14761 tggctctagg tcaaactgtt aaagcaatcg aaggtgacgg taaagttgaa cgcttgatta
    14821 ctgacaaaga aagctttgac gtggatatgg ttatccttgc agttggtttc cgtccaaaca
    14881 cagcccttgc aggtggtaag atcgaactct tccgcaacgg tgccttcctt gtagacaaga
    14941 aacaagaaac atctatccca gacgtttacg ctgttggtga ctgtgcgact gtttatgaca
    15001 atgctcgtaa agatacaagc tatatcgctc ttgcttcaaa tgctgttcgc actggtatcg
    15061 ttggtgccta caatgcttgt ggacatgaat tggaaggaat cggtgttcaa ggttcaaatg
    15121 gtatctcaat ctacggtctt cacatggttt caactggttt gactcttgaa aaagcgaaag
    15181 ctgctggtta caacgcaact gaaacaggct ttaacgatct tcaaaaacca gaattcatga
    15241 aacatgacaa ccatgaagta gcaattaaga ttgtctttga caaagatagc cgtgaaattc
    15301 ttggtgccca aatggtttcc catgatattg caattagcat gggaatccac atgttctcac
    15361 ttgctatcca agagcatgtg acaattgata aattggcatt gacagacctc ttcttcttgc
    15421 cacacttcaa caaaccatac aactacatca caatggctgc ccttacggct gaaaaataaa
    15481 aatgaatgag ctatctggcc ttaagttaag gtcagatagt ttttagctaa tctgtcccca
    15541 tacaattata gtttttttat cttgtgcttc attctgttct gacttaaaat gaaaaggtag
    15601 ctaccaatac aaatgatgag gataaaacaa atgactgaaa atcgttatga actaaataaa
    15661 aacttggcac agatgctcaa gggtggtgtt attatggatg tgcagaatcc tgaacaggct
    15721 cgtatcgcag aagctgctgg tgcggcagct gtgatggcct tggaacgaat tccggctgat
    15781 attcgtgcag ctggaggagt ttcccgcatg agcgacccaa agatgattaa ggaaatccaa
    15841 gaagcggtta gtattccagt aatggctaag gtcagaatcg ggcattttgt tgaagctcag
    15901 attttagagg ctattgaaat tgattatatc gacgagagtg aagttctatc tccagctgat
    15961 gaccgtttcc atgtggacaa gaaagaattc caagttcctt ttgtctgtgg tgctaaggat
    16021 ttgggtgaag ccttgcgtcg tatcgctgaa ggtgcttcca tgattcgtac caaaggagaa
    16081 ccagggacag gggatatcgt ccaagctgtt cgtcatatgc gtatgatgaa tcaggaaatt
    16141 cgccgcattc aaaacttacg tgaggacgag ctttatgttg ctgccaagga tttgcaagtc
    16201 cctgtagaat tggtccaata tgttcatgaa catggaaaat tgccagttgt aaatttcgct
    16261 gctggaggtg ttgcaacgcc agcagatgct gcgttaatga tgcaactagg ggcagagggg
    16321 gtctttgtcg gttcaggtat tttcaagtca ggagatcctg ttaaacgagc gagtgccatt
    16381 gttaaggctg tgactaactt ccgtaatcct caaatcctag ctcaaatctc tgaagattta
    16441 ggagaagcca tggttggtat taatgaaaat gaaatccaaa ttctcatggc tgaacgagga
    16501 aaatagatga aaatcggaat attggccttg caaggggcct ttgcagaaca tgcaaaagtg
    16561 ctagatcaat taggtgtcga gagtgtagaa ctcagaaatc tagatgattt tcagcaagat
    16621 cagagtgact tgtcgggttt gattttgcct ggtggtgagt ctacaaccat gggcaagctc
    16681 ttacgtgacc agaacatgct acttcccatc cgagaagcca ttctatctgg cttaccagtg
    16741 tttgggacct gtgcgggctt aattttgctg gctaaggaaa tcacttctca gaaagagagt
    16801 catctaggaa ctatggatat ggtggtcgag cgtaatgctt atgggcgcca attaggaagt
    16861 ttctacacgg aagcagaatg taagggagtt ggcaagattc caatgacctt tatccgtggt
    16921 ccaattatca gcagtgttgg agaagatgta gaaattctag caacagttga taatcaaatc
    16981 gttgcagccc aagaaaaaaa tatgttggta acttcttttc atccagaatt gacagatgat
    17041 gctcacttac accagtactt tatcgaaatg tgtaaagaaa aaagacagta aaaaagctca
    17101 aaaaatcact tcctgtgcta tactgtaatt gaaatttttt tagtttttgc gttagaactg
    17161 tttcctcagt cctagcgcct tttctttttg ataagtctgc ttggtggaga gtagtttgta
    17221 aacgattctg agaatcttat gagcacaagc aatgacggct ttcatcttgc ttcctctttg
    17281 ggaaattcga ttgtaaaact ctaagcaggc agagcctgct tagagtttta catatgctac
    17341 tatctttgtt atagctaact taaattctca tttattaagt atacctaagt tttatgttta
    17401 aattttgtat agaatagttg tatcacttaa caaagctatg tttacgcttt caatcaagtc
    17461 tcatttatga tactattatg gtaatagaaa aaattcttag ttcgctaaag acctttattc
    17521 gagatccaga ggaaatagaa attttatcca ttaaaaatac gtttcataag ttacttactt
    17581 gatattaata gaattccaat attgtataat taaatcaaag atgacactgg aatcaggagg
    17641 atttattatg gttaataatg tagctgttaa agtctcaaac ctttcaaaag aatttttgtt
    17701 agggcaagac aaaactgtct ctattttgaa agatatttcc ttatctgtca attatgggga
    17761 atttgtatca atacttggtg tcagtggttc tggaaagtct actttgctaa gttgcttatc
    17821 aagtttatct gaaccaacaa gtggcgaagt tgttatcaat ggtgtaaatc catatacctt
    17881 aaaagaaggg aagcttgcta aatttagaag acaagatatt gcaataattt ttcaaaacta
    17941 taatctggta cctgctctac ctgtactaga aaatgttaca cttcctctga gactatcagg
    18001 aaagagtgtt gatagcaata aagtaaaaaa aatgttggat agtttgaatt ttaaagcaga
    18061 actatcatca ttagttgcta ccttatcagg tggagaacag caaaaagtgg ctattactcg
    18121 tgcaataata gctgatagta aaattatttt tgctgatgag ccaacaggag ctctggacag
    18181 cgtctcaaga aaacttatat ttgaaacact tcgtaattta gcgagtcaag gaaaatgtgt
    18241 tcttatggtc actcatgata ttgagttggc ttcaaaaact gacagagcac tcattttaaa
    18301 agacggaaaa atatctcgac aaattattaa accttcagct gatgagctct accaagcact
    18361 tgaaagtagt aaagattaat ttgaggagga tttattatgc taaaattaat catttaccaa
    18421 tttcagtact caaaaagaca atggttagga acaataccat tactatttgt atctagcctg
    18481 attgttggaa catctttatt tggtattgct agttcaatca agactgctaa tattaacgct
    18541 tcacaacttt ttcaaatgct aataattttt ggcgggacta ctctattttt ccttatttca
    18601 aataatataa gactgctaat agatatcttt aaaaaggatt accaattatg gactatctta
    18661 ggcgcaagca gaactcagct atctttatta gtatctggac agttttattt aatggcagtg
    18721 attgttagta gtattggtac aatactttca tttatcatgg cagatagtta ttacaaattt
    18781 ttacaaaatt tattaggaag agatgagtta cctgatttag ttattacagc caacattcaa
    18841 tcaattttat tgagtatttt tatagtccca acaattgtcg ggataggggc ttacttttat
    18901 tcaagtcgaa tacttaaaat atcatcaata ttaaaaccaa aaaagaaaaa aagaaaagtt
    18961 acagtaactg gatttgttaa catctctgtt cgtttattcc tatggctact atgtataggt
    19021 tctattgttt cagcaggttt tatcagaaac aaagaaataa ttgaaaaaca gtcaagcata
    19081 atattatttt tattaattat tcacatcctt attattcaat cactatctcc atcaattcaa
    19141 atgtttctaa taaaattttt aatgaggata tttccaactg aaaattatgt aattaataca
    19201 ggcttttgga atctactatc caatcctagc tatttgaaaa gtatacaaac ttcaatgagc
    19261 atgggagtaa ctctcatttc tgggtttatt ctttacaccc aaaatatgta ttcattcatg
    19321 aatacagcaa acggagtaaa cgaagcaaga gcttccttta ttgcttatat gtctgcacca
    19381 attattctga ttattactag ttctatttct cttacaattt tatcttctaa taaagatatt
    19441 gaggacatta aacagttaaa gacactggga gtgtcaagat tacaactttt taaaatacgt
    19501 ataggcgagg caataataca ttcggtgtta attttattag tgtcagtaat tttcaattta
    19561 attattttaa ttttagttag cattattggc caatttttag gtcgtagttt agtagatata
    19621 tcaggtttct ggcaaccgag tcttatagtt atttctttgt tagttatttt ttatagtatt
    19681 acaaagggat tttatttatt tcaagataga taaattggaa tagttactga accaaaaaga
    19741 a
//
LOCUS       DAVLHM010000039        18752 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLHM010000039 DAVLHM010000000
VERSION     DAVLHM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.039"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..170)
                     /locus_tag="VXE45_001591"
                     /pseudo
     CDS             complement(1..170)
                     /locus_tag="VXE45_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(216..449)
                     /locus_tag="VXE45_001592"
     CDS             complement(216..449)
                     /locus_tag="VXE45_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0789605.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(455..1447)
                     /gene="plsX"
                     /locus_tag="VXE45_001593"
     CDS             complement(455..1447)
                     /gene="plsX"
                     /locus_tag="VXE45_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0789606.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1444..2214)
                     /gene="recO"
                     /locus_tag="VXE45_001594"
     CDS             complement(1444..2214)
                     /gene="recO"
                     /locus_tag="VXE45_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0789607.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2211..3380)
                     /locus_tag="VXE45_001595"
     CDS             complement(2211..3380)
                     /locus_tag="VXE45_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0789608.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3529..4539
                     /locus_tag="VXE45_001596"
     CDS             3529..4539
                     /locus_tag="VXE45_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0789609.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(4775..5212)
                     /locus_tag="VXE45_001597"
     CDS             complement(4775..5212)
                     /locus_tag="VXE45_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0789610.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5297..7930)
                     /gene="polA"
                     /locus_tag="VXE45_001598"
     CDS             complement(5297..7930)
                     /gene="polA"
                     /locus_tag="VXE45_001598"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0789611.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVGTEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(8539..8789)
                     /locus_tag="VXE45_001599"
                     /pseudo
     CDS             complement(8539..8789)
                     /locus_tag="VXE45_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8782..8898)
                     /locus_tag="VXE45_001600"
     CDS             complement(8782..8898)
                     /locus_tag="VXE45_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0789612.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(9113..9466)
                     /locus_tag="VXE45_001601"
     CDS             complement(9113..9466)
                     /locus_tag="VXE45_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0789613.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAQNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            complement(9584..10552)
                     /locus_tag="VXE45_001602"
     CDS             complement(9584..10552)
                     /locus_tag="VXE45_001602"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0789614.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(10697..11257)
                     /locus_tag="VXE45_001603"
     CDS             complement(10697..11257)
                     /locus_tag="VXE45_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV0789615.1"
                     /translation="MSNFLGSVHLLGVLFPDSTFLNAFESAIVAPLVEESLKLLPLVF
                     VLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIHTDLPEGFDFTISRILERIISGIAS
                     HWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAI
                     PVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(11263..12614)
                     /locus_tag="VXE45_001604"
     CDS             complement(join(11263..12173,12173..12614))
                     /locus_tag="VXE45_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0789616.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(12611..12955)
                     /locus_tag="VXE45_001605"
     CDS             complement(12611..12955)
                     /locus_tag="VXE45_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789617.1"
                     /translation="MYEEKQYFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDFMNCTPKV
                     RQKKSNFWGVLL"
     gene            complement(12976..13473)
                     /locus_tag="VXE45_001606"
     CDS             complement(12976..13473)
                     /locus_tag="VXE45_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0789618.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(13546..14907)
                     /gene="radA"
                     /locus_tag="VXE45_001607"
     CDS             complement(13546..14907)
                     /gene="radA"
                     /locus_tag="VXE45_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0789619.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYISGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(14921..15436)
                     /locus_tag="VXE45_001608"
     CDS             complement(14921..15436)
                     /locus_tag="VXE45_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0789620.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(15438..15881)
                     /locus_tag="VXE45_001609"
     CDS             complement(15438..15881)
                     /locus_tag="VXE45_001609"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0789621.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(15941..16034)
                     /gene="ffs"
                     /locus_tag="VXE45_001610"
     ncRNA           complement(15941..16034)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXE45_001610"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(16067..16534)
                     /locus_tag="VXE45_001611"
     CDS             complement(16067..16534)
                     /locus_tag="VXE45_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0789622.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(16735..18021)
                     /locus_tag="VXE45_001612"
     CDS             complement(16735..18021)
                     /locus_tag="VXE45_001612"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0789623.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(18252..18488)
                     /locus_tag="VXE45_001613"
     CDS             complement(18252..18488)
                     /locus_tag="VXE45_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0789624.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         5523 a         4574 c         3227 g         5428 t
ORIGIN      
        1 ttctcaacct tgcttctctc cttagatagc gcatgattac aggctttatc ttcaactgtt
       61 agcggcttga gtttgctgga tttacgtgga gtttgtgctt gaggatatat cttcatgagc
      121 ccttgataac cactgtcagc caagatttta ccagcttgtc cgatatttct catttctaaa
      181 aaccatctac ttccgttgac ttggaactcc gattgctatt ttccttgaat gattttaacc
      241 acatctccta cgttttggag ttggtcaatt tcttcatcgc tgatttcgat actaaattca
      301 tcttccaggg tcaagataaa ctccatcaag tcaacagaat ccgcatccaa atcgtctttc
      361 agactcaagg attctgtcac gacaaagtcc tctccctgtc gctcttggat aatggtcaca
      421 atacggtcaa aaatttcttt ttctgtcatc tcttttattc tcctgaaaat tcacgcgcag
      481 tctgggcaac tacgtctgtt tctagcatgg tacgaatctg gcgaatcgta ctataaacag
      541 ccttggcatc gcttgagcca tgagtcttga caacaggtgc cttaacacca aacaagaccg
      601 ctccaccaac atctgaataa ttgagctgtt ttttcaaacc tctgaggctg tccttgagaa
      661 ggagggcacc tagtttcgct cgaagaccac cacctgtaat agctgtcttg agcaagccca
      721 tgattcccat agctgtccct tcgatggatt tgagcacagc gtttcccgtg aaaccatctg
      781 ccacaacaac atctgcaacg ccattcatca aatcacgcgc ttccacgttt ccgataaagt
      841 tcaaactttc atcagccgcc agtaattcat aagtttcctt acgaagcggg tcgcccttgc
      901 tactctctgt tccgttgttg agcaaaccaa cgcgtggttg cgcaatgcca cggacatttt
      961 tagcatagaa ggaacctaga accgcatatt gatggaggtg ctgggctgta ttttctgcat
     1021 tggcaccaag gtctagcatg tcaaaacctt ttccatcaac ggtaggcaag gtagacatga
     1081 gtccaggacg gtcgatattc ttgatacgac ccacgatgaa gaatcctgct gccaacaagg
     1141 cacctgtatt cccagccgaa aggacagcgt ctgcttcacc atctttgaca gccttggctg
     1201 ccaataccat actggcattt ttcttattcc taatagctct cgtaggttca tcatccgaat
     1261 caatcttctc atccgtatgg ataatgctga cgcgctctgt cgctgtcaga tattgcttga
     1321 ttttagcttc atctccgtaa agttgaacct cgatatctga aaagtcagat agggcttgat
     1381 tgacaccctc aacaatggcc tgaggtgcgt aatcgccccc catggcatct actgcgattt
     1441 ttttcatttc ttttcctctt ttagtaattg tccccagtct gctagggaat caataaattt
     1501 ctttgatttt aggtgaatcc caacgtactc ttcatataat tgatccataa attggcgtag
     1561 ctcttgcttg attccaggct tgagcgaaat ggtctccaaa gtctcaaaat caatagcttg
     1621 aaattgattg agcagatagg ggatattggg attgagatga caacgtctct tatcctcatg
     1681 ataatgctct ggacagaggc aggctccata tttgaaagaa aagtcaaaag cctgaccaac
     1741 ccgatggcag aagacacact cattaaaatt gaggctgatt ccaaatcgag tcaaaatttg
     1801 aatttcaaaa atattggtca aaacctgata atccaagcct gcttccatca actccaaagt
     1861 cttttgcaaa aaagcaaaca agggagcatc ctgctgattg tcctgcaaac tagcatctgc
     1921 aagagctgcc acataggtcg cataggccat gacaaagagg tcactattaa tcttgggaaa
     1981 agtcatgacc tcatgatagt cttcgatgta actgagtccg tcatcattga ttcgcaagag
     2041 aaatcgtgcc agcaccaagg gctgaataac aggcgccagc ttagactgac cagcgtgttt
     2101 gacaaaaaac atgcatttgc caacctgctc tgtaaaaatt ttgacgagct tgtcatcctc
     2161 acgaaaattg cgattgtaaa gcaccaagcc ttgactcgtg atagactgaa tcatgcttct
     2221 ctcatgtact cctcaagtcg tttcatggct tctttgatag tctccatgct ggctgcataa
     2281 gataggcgga cgtagccttc cccgtaacgt ccaaaggctg caccagggat aaaggcaacg
     2341 gccttcttct gagcaaaatc cttcagaaaa gcaaaggagt cttgattgta gcccgctgga
     2401 attttagcaa aaatatagaa ggcaccgtct ggtttgataa tctcaaaacc aagagcagtc
     2461 attttttcga tgatatagtc ccgacgctgg atatattcct tcttcatggg ctccgcatca
     2521 tttttaccag ccgtcaaggc ttctaccgca gcatgttgcg ccatggtatt tgcggcagtg
     2581 accaagtact ggtgactctt gattaactgg gctgtgaagg tcgccggagc gaaaatcagc
     2641 cccaaacgcc aacctgtcat ggcatgcgat ttagacaaac cattgataat aatagcctgg
     2701 tctctcaaca tcgttcctag agacacatgg gcttcgcctg tgtaggtcaa ttctgagtaa
     2761 acctcatcac agacaacaaa aacttcgtac ttgcgtaaaa cagctgccaa ggcctctaac
     2821 tgctctcgac tgtaggtaat tcctgtcgga ttggctggat agttgagaat aaccgctttg
     2881 agcttatcac cctgctccaa aatggccttc tccaacatct caggagtcaa gacaaaacca
     2941 ttttcagtcg tatcaatctc aacaatttct gccccaacta agttaacaat cggttcatag
     3001 cctggataag caggagctgg caaaagtacc ttgtctccct cttccaaaat agccgtcaaa
     3061 gtcgcagata aagcctctgt cgccccaatt gtaaccaaga tttcattttc aggagcatag
     3121 tccagttggt acttttcctt aacaaagtca ctggctgcct gacgtagagt cagcagacca
     3181 ctcatccctg tatagtagga ttggttctga tcaatcgctc gcttggccgc ctccttgaca
     3241 tggtctggcg ttgtaaaatc aggttccccc aaggtcaaac gcaagacccc aggaatctcc
     3301 gaaatagcct ggtcaaactg acgaatcaac gaaacttgaa ttttatctaa ctgtttatta
     3361 aagcgcttag ttaagtccat agatacctcc tactttcaaa acgtatctct attatactac
     3421 aaaagccccc cgaccgcaaa aatacattag agaatagctt tccactttct attttacttt
     3481 tcctgtttat aggtctataa tggtaataga ttttatttgg aggtttttat gtcatttcta
     3541 tcaaaaaatg gagcaggtat cttggcctgc cttctcattt ccatcctatc ttggtactta
     3601 ggaggattct tccctgtgat tggcgcgccc gtttttgcca ttttcatagg catgctccta
     3661 catccctttc tctcgtccta taaacaactg gatgctggtt tgacctttag ttccaagaag
     3721 ttgctccaat atgccgttgt cttgcttggt tttggtctca atatctcgca ggtcttcgca
     3781 gttggccaat cttcactccc tgtcatcctg tccactatct caatagctct gattattgcc
     3841 tacctcttcc agcgtttctt tgcactggat acaaaactgg ctaccttggt tggagtaggt
     3901 tcttctatct gtgggggttc tgccattgca gcgacagcgc ccgttattga tgctaaggaa
     3961 aaggaagtag cccaagccat ttccgttatc tttttcttca atgtcttggc tgcgctcatc
     4021 tttccaaccc tcggcacctg gcttcatcta tccaatgaag gcttcgccct ctttgcaggg
     4081 actgcggtca acgacacttc ctctgtaacg gctgccgcca gcgcttggga cagtctttac
     4141 caaagcaata ccctcgagtc tgcaaccatt gttaaactca cacgtacttt ggccattatc
     4201 cctatcacgc tctttctatc ctactggcaa agtcgccaac aagaaaacaa gcaaagccta
     4261 caactgaaaa aagtcttccc actttttatc ctttacttta tccttgcatc gctcctaacc
     4321 acccttctga cctctctcgg tgtgtctagt agtttcttta cccctctcaa acaactctct
     4381 aaattcctca ttgtcatggc catgagtgct atcggtctca aaaccaatct ggtcgctatg
     4441 gtcaaatcca gtggaaaatc cattgttctc ggagccatct gctggattgc catcatcctc
     4501 accactcttg gtatgcagac ccttatcggc attttctaat actcttcgaa aatctcttca
     4561 aaccacgtca acgtcgcctt gccgtatata tgttactgac ttcgtcagtt ctatctgcaa
     4621 cctcaaaacg gtgttttgag ctgacttcgt cagttctatc tacaacctca aaacagtgtt
     4681 ttgagcagcc cgcggctagt ttcctagttt gctagtttgc tctttgattt tcattgagta
     4741 taacacaaaa ggtagcccat cagctacctt tttcttatgc ttcctcaatc aagcgagtat
     4801 gttctctctt gatacagcga ttcatcacga tatcatcaca tccaccatca cgcaaaatct
     4861 ctttcgcttc taaactttca agtcctagct gtgcccaaaa aatcttggca tcagctttga
     4921 gaaaatcacg cgccacatcg ggcagaaatt cactgcgacg ataaacattg acaatatcta
     4981 caggaaaagg aatttcagcg aggctagcat aagccttttc acccaagatt tcgccacctg
     5041 ccgccttggg attgactggg atgattttat agccccgagc ctgcatttcc tttgttactc
     5101 gattgctagt tgtttcttca cggtcagaca aacccaccac agcaagggtt ttactcgttg
     5161 cgagatactg acgaatcacg ccatcacttg gattgataaa ttcttgactc atagaaatcc
     5221 tcctttttca tcagtatagc acattttgaa aaggtttgca gaattctact acaaaaaagg
     5281 aggactagcc ccctttttat ttagcctcgt accaggttgc cccttcattc tcatctgcga
     5341 taagaggaac actgagttga atggcttctt ccatggtttg tttcaccaat tttttcatct
     5401 ctaccaattc agatttaggc acttcaagga cgatttcatc gtgcacttgt aacagcatct
     5461 tagtctgata accacctgca accaaggctt tatccagctg aatcatggca atcttgagaa
     5521 tatctgctgc cgaaccctgg ataggtgagt tgatagcagt tcgctccgca aaaccacgaa
     5581 tattgaagtt gcgcgaattg atatctggca actcacggcg acgcttaaag agggtctcta
     5641 catagccctt atcacgcgcc tcccgcacca cttcatccat gtagttttta atacctggaa
     5701 aacgttcaaa gtaggtatca atgtaggctt tggcttcctt acgactaatt cccaaattat
     5761 tagacaagcc aaagtctgaa atcccataaa ccactccaaa gttaactgcc ttggcattgc
     5821 gacggtcatt tgcagtcaca ttatcaggac gctcaatgcc aaagacccgc atggctgtcg
     5881 aagtatggat atctgccccc tcttggaagg ccttaatcaa gtgctcatcc ttagaaatat
     5941 gcgccaaaac gcgcaattca atctgtgaat agtcagagct gagtagcaca ctatcctccc
     6001 actctggcac aaaagccttc cgaatcaagc gcccttgttc caatcgagca ggaatatttt
     6061 gcaagtttgg atccacacta gacaaacgcc cggtctgggt caaatcctgc atatagcgag
     6121 tatgaatctt tccatcagcc aaaatccagt cctgcaagcc aattacataa gtagattgaa
     6181 tcttagcaat ttgacggtaa tccaggattt tcttaacaat cggagcaata ggagcgagac
     6241 gctccaacac atccactgct gtcgaataac ctgtcttggt tttcttagtg tattctagag
     6301 gaagtcccaa tttctcaaag agaagcacgc ccaactgctt aggcgagttg acattaaact
     6361 cctcaccagc cagctcgtaa atctcttgag tcagtttttc aatgacaagc tcattttcag
     6421 cctgcatctc aagcaaggtc tctttcttga ccacaatccc agcaatttcc atcttggcaa
     6481 gaacaaaagc cagaggttgc tccatatcat aaagaagctc taattgccca ttttcgctga
     6541 gtttttcaag taaaataggc tctgttccta ccaaaacagc aagtttacaa gctaagtgtt
     6601 ccaagaattt ctcacgttca ggaatggcct ttttaacacc cttaccgtag aaagtttcat
     6661 catcaaccaa gtaagtctga ccataaagac tagcgatggt cgcaatttca ttgtcctcca
     6721 cagtcgaaag gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc aaatccacac
     6781 caaaacgttg caaaagaact ttaaccttct taaagtcata aactctcaga gatgtttttt
     6841 ctaagaaatc cttgaaaatc gggtcttgca acagctcaag cttgtctgtg gcatagagct
     6901 tatccccaca agaccaggca aatccaacca aattatccgt atggtaattc tcaccaaaaa
     6961 gctcaaagtg gaagatagac tcttcactca gcatatcttg actgatttgg tcaacaatag
     7021 taaaatccaa accctcagcc acatcagctg acgacacatt taaagcctgc ttgagctgtt
     7081 tgaagcccat ctcatcgtaa aatttcccaa gattttcaac atctggacca ctatagacca
     7141 agtcctctaa accaatcgca atcggtgcct tggtatcaat ggtcgctagt gttttagaca
     7201 aaaaggcctg ttccttgtca ttgatgagat tttccttcat cttagaagtc ttcattccat
     7261 caatattttc ataaatcccc tcaagcgaac catgctccag caagagctta atacccgtct
     7321 tttcaccgac tttggtcacc ccagggatat tatccgactt atcacccatg agcgccttga
     7381 gatcgataaa ctgagctggt gtgaggccca tttcttccat gaggtaatct ggcgtaaagg
     7441 cctcaaactc agccacacct ttcttggaaa tttcaaccac cgtatgctca tccgtcagct
     7501 gaatcaaatc cttgtcccca ctgacaatgg taatatcaaa accatcctgc tctgctagct
     7561 tatccagcgt cccaatgatg tcatccgcct catactgagc cagctcatag tgacgaatcc
     7621 ccatatgatc cagcaactca cgaatgaaag gaaattgctc acgaaactca tcaggagtct
     7681 tggcccgacc acccttatag tccgcataca tctctgtccg gaaggtcgtc tttcccgcat
     7741 caaaagccac caaaatatga ctcggctcaa cccgctccaa caaatgactc aacatcaact
     7801 gaaaaccata aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg tccaactgct
     7861 gatacagcgc aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat aataattttt
     7921 tcttatccat acacccatta taaaggaaag aatcaaaaaa taccattggg aagagctaga
     7981 gcaagtattt ttcaaacttt ttccgaataa atagatagag ccagagaatt tagtaaacct
     8041 agatttaaaa atgtgatata atatagtata ttgaatctat aatagtacac cttgactgct
     8101 aaaatatttc tataaattaa tttgactttc ctgatagagt tgtttcacat cttatttcaa
     8161 ctcactatag aaggaggaaa aggagggctg ggtggctaac ttcattatag aactttcaaa
     8221 aagatgaaaa aatagcgtca aagaggcttt tttctcttta aaacaggaaa tttcaaagac
     8281 aatcttgcga ctatccaaac tgtacgaata gcgagacata acttacttcg ctaatactat
     8341 agtagattga aactagaata gtacacctcg atttctaaaa cattgttaga aatcgatttg
     8401 actgtcctga acgatttgtc ctgttattat ttcattttac tatatcttat aaaaagatag
     8461 aaatgtcaag caaaaatgac aagtattttg ataataaact tgccatccca tcaactttct
     8521 actatataaa gtatgaactc atagcaagga ctcaaactca gccacggtca tgcctaattg
     8581 ctcactcgca acctcaggtg ttagaagacc ttgacgtact agatttacta aacctacttt
     8641 taatccctct tcaaggcctt cttctcgtcc ttgttcacaa ccctctgcac gaccacgttc
     8701 aataccacgc tctagtcctt gttcaatacc ttcgcatagt cctgtgctaa caagacttgt
     8761 tcttctcgca tatgtagttg actaaacatt ttcctgtcct cctcggacca gctcttgtag
     8821 tccagcagtt gatttgcttg ggtaatggct cgttgcggtt gctgggtaaa gggcttgttg
     8881 ccgaaaaact ccaaccatgg cttgcgaacc ttgtctttgc tggtttctct gtatttttta
     8941 attccaagaa tgccatctta accagatggt tttcctgtcc attgttggta atcgccaata
     9001 cctcacctgt tgtgtcttcg cgcatactaa cgctatgaaa agccaggcca tctgagaaat
     9061 aattgctatc cacgatagca atgacgtaaa caggagcgat gtgtttgtag atctagtgag
     9121 tatcaccttc tcgctgacga attttttcaa gattttgatt aacctgactg cacaggtaag
     9181 cccacaagtg attgatgaaa aaattctgat gatggacttg aatctcaata attacttgag
     9241 taccgttatc caactccgcc aagacgtcta tactggtata aaaatcctgc accgagtaag
     9301 gcatggagag taatacgtga atattgctac cctccaaaat ggtcacattt tgggctggca
     9361 aatccagcat atcgcgaata aattgacaag taatttctgg attgctaaag attttcttag
     9421 ctaccaagtc attggttggg ctaatgcccg gatgacgtac agtcatattt cttctctttt
     9481 tattatatca cagttttaaa tctagcttta ctagattcac cgctactatc tatttattcg
     9541 gaaaaaagac gaaaaaacct gagaatcatc tcaggcttgg tcattaaatt tttttctcaa
     9601 tatcgaaaag tggagaaagt ggtcgttttt catgaatacg tacgatagca tcccctagga
     9661 gatgagcgat tgaaatctgc tcaatcttat caatcaaacg ctcttctggc agatagatgg
     9721 tatccaaaac aaccaatttc ttaatagctg atttttggat attgtccgta gcaggaccag
     9781 aaagaactgg gtgcgtacag cttgcataga cttcaacagc accagcttcc gcaagagcat
     9841 ctgccgcatg acaaatcgtt ccagcggtat caatcatatc atcaatcaag atacaagtct
     9901 tgccttcaac cttaccgatg atgttcataa cttcactagt attcatctta tcaacgctac
     9961 gacgtttatc aataatagcg atagaagttt tcaaaaattc tgccaactta cgagcacgag
    10021 tcacccctcc atggtccggg ctgacaacca catagtcaga accaaccata ccacgacgct
    10081 caaaataatc tgcaatcaga ggagcaccca tcaaatgatc cacaggaata tcaaagaatc
    10141 cttgaatttg cgcagcatgc aagtcgatgg tcaataaacg atccactcca gctacttcaa
    10201 gcatatttgc gacaagtttt gaagtgattg gctcacgcgc tctcgccttt ctatcctgac
    10261 gtgcataccc atagtaaggc atgacaacat tgacagattc tgcactcgca cgcttcaaag
    10321 catctaccat aatcaaaatt tcaagcagat tgtcatttac aggcgaacta gttgattgta
    10381 ggataaagac gtgtttccca cggattgatt cttcaatgtt gacctgaatc tctccatctg
    10441 aaaattggcg aacacttgat ttccccaact ctatcccaat ctcctgcgcc acacgttctg
    10501 ccaattcttt attagaagaa agggcaaata gctttaaatc agaaaaagac atgatttcct
    10561 ccggtatata tgtataactt gtgcttttca caagattttc catctaccat tgtagcgctt
    10621 tttgcactat ttttcaatca aaaataaaag aagggcacca tatttgtacc cttgcatcat
    10681 tcttttgaaa aatattctag gtcatcaact cattgtgttt ctcaacaaag caataagcat
    10741 gataaaaacc atagagagca atagccgtaa ccactggaat cgctaaaggc aactctgttt
    10801 ccaactccac aaaaggagag ttaaacaaga agtgagttcc caaggctaaa cctagaaaaa
    10861 taaggccctg tttcttgcca accttctgtc ctttataggc tctgtaaagc aagtaaacac
    10921 ctactacagc tagacctgaa aaagtccagt gagaggcaat tcctgagatg atacgctcta
    10981 aaattcgcga aatagtaaag tcaaagccct ctggcaaatc cgtatgaata taaccaatat
    11041 cctcaatcat ttggaatccc aaaccggaag caattccaag taaaaacaaa gattttaatt
    11101 ttcgcacagg aatcaaagcc aaaacaaaaa caagtggcaa taatttcaag gattcttcta
    11161 ccaaaggagc cacaatagca ctttcaaagg catttaaaaa tgtactatct gggaaaagaa
    11221 cccccagtaa atgtactgac cccaaaaagt tagacaaata atttatccaa aggatttagt
    11281 tctgtactgc acagaactaa gtccttttag ttttacctta attcgtttgt tgttgtagta
    11341 atcaatgtag tccacaatag cttgttcaag gttttctaaa gatctaaagt tcttctcata
    11401 gccataaaac atttcggatt ttaaaatgcc aaagaaagat tccatcatgc tgttgtctgg
    11461 gctgttgccc ttgcgtgaca tggatgcttg aattccctta ctctctagga accgatgata
    11521 agaatcgtgt tggtattgcc agccttggtc actatggaga atcgtattct catagtattt
    11581 ctctgtaaag gcctgttcta acatactctt cacttgttct aagtttggcg aagtagaaag
    11641 atgataagca atgatttcac tgttaaaacc atctaaaact ggtgataaat agagtttctg
    11701 tgtgctattt ggaatggcaa actctgtcac atctgtatag cacttttcca ttggcctcga
    11761 tgcttcgaac tggcgttgaa tgagattctc tgctttcttg ccaatctctc cttggtagga
    11821 agaatacttc cgtttacggc gaattcgagc cgttaaacca agaattctca tcaaccgttg
    11881 aactttctta tgattgacca caaaaccacg attccttagt tctaaatgga ttcgacgata
    11941 gccatagttg cctttatgtt cattatcaat gccctgaatt tcggttttaa tctctttatc
    12001 tttatcaacc ccatccagtt gtttcaactg ataatagtaa gtcgagcgag ctaaacgtgc
    12061 tgtttcaaga agaaaatcta gtcgaaatcc tcctgaaacc atttctctaa ctgtctctgc
    12121 ctttctcgct ctagggcttc gtccctttcc tctaactctt ttaacttttt taggtaggcc
    12181 acctcagtcc gtaagcgttc attctcctcc tggagtcgtt ctagttctgt catttcttcc
    12241 caagtcttct tccgtttacg tcccatttta gctggtctcc ctcttgtttt ctcaacaata
    12301 gtatacccgt ttttcttgta ttgtgccggc caaaatgaaa gcattccttg gtttgggagg
    12361 gcataatcaa gactaatact tctttgtgaa caaccttcca gtaaggcttt atccatcatt
    12421 tcttgtttca atttagaaga atagtgacga ttcttccctt ttttaacgat ttctatgcca
    12481 taacggtcaa ttaatttcac catgtacttt agaccagaaa catccacacc aaatcttttt
    12541 gaaagctgtt tgaagctttg tccttgcttt cttagttcat agatctgaac tttatcttca
    12601 taactcaatt tcataataaa acaccccaaa agttagattt tttctgtcta acttttgggg
    12661 tgcagttcat aaaatcatgg atataagtat tagcaaaact agacaaccag cctgaaagga
    12721 acatccctcc caataaagac agaatcaaaa ccttctttgg caattcccat tttttcccaa
    12781 tacggaagag aaaataaaga gccggaatca tgtaaaagag agctagaaag atagaaactc
    12841 ccattagtcc atattccgca cctgacctcg aaccgtccgt atagtagatg gtttcatact
    12901 gtaaaccaat acatagcaat aaaataaaaa taaaatactg cttttcttca tacactttct
    12961 ttctaaatga agtatttata attctacgac tgtcatactt cctgtatcaa cattgtaaat
    13021 agcaccagag ataatgacat cgtctggtat taggggagac tcgataagca gttgcatatc
    13081 ctcgcgtaca ctctcttcta tatcttggaa gggcaagaag tcctggtctg acacatctac
    13141 acctaattcc tcttttaaat actcctgaaa aggttcattt tcaaaggtct gagcaccaca
    13201 gtctgtatgg tgcaatacca caatctctct tgtccccatt tgttgctggg aaataactag
    13261 cgaacgaatc atgtcttcag tcactcgacc acctgcattc cgcaagatat gagcatcccc
    13321 aagtgccaaa cctagagctt gcgcaacgtg caaacgtgag tccatacagg tcacaatagc
    13381 tactcttgtt ttgggtttaa gtggcagatt taactgccca tgtagggcaa cataagcctg
    13441 attagcttgc ataaactgtt caaaatacga cacgattccc tccttgaaaa tttgatagtc
    13501 aaatatttct cctatcttat catttttaag agaatttgtc acggattatg caaagacctt
    13561 tttcaaaact tcctgaatcg ttgtcacgcc aatgacctga atttccttag gcagagtgat
    13621 tcctgtcaag gaattcttag gtacataaat cttagtaaag cccagtttag cagcttcgtt
    13681 gatgcgttgc tcaatacgat tcacgcgccg aatctctcct gtcaagccca gttctccgac
    13741 aaaacattcc tgaggattag ttggcttgtc tttgtagctc gaagcaatag caactgcaac
    13801 agccaagtca atggcaggtt catccaattt aacaccacca gcagatttga gataggcatc
    13861 ctgattttgc aagagaagcc ctgcccgttt ttccaaaaca gccataatca agctagcacg
    13921 gttaaaatca agtcctgtcg tagtacgctt ggcatttcca aacatggtcg gtgttaccaa
    13981 agcctgaacc tccgccaaaa tcggacgcgt cccttccatg gttacaacga tggaggaacc
    14041 agttgcccca tccaaacgct cttctaggaa aacttgactc ggattgagta cctcaaccaa
    14101 gccgcccgac tgcatctcaa aaatcccaat ctcattagtg gaaccaaaac gatttttgac
    14161 cgctctcaaa atacgaaagg tgtggtgacg ctccccttca aagtaaagca ccgtatccac
    14221 catatgctcc aacatacgag gcccagccaa ggttccttct ttggtcacat gacctacgat
    14281 aaagatggca atgttattgg tcttggccaa ctgcatgagt tcagcggtca cttcacgtac
    14341 ctgagaaaca gacccctgca cccctgaaat ctcaggagac atgatggtct ggatggaatc
    14401 aataataaga aagtctggct ggatacgctc cacttctgca cgaacactct gcatattggt
    14461 ctctgcatag agataaaact cactatcaat atcacctaag cgctctgcac gtagtttaat
    14521 ctgctgggca gactcctccc cactgatata gagaactgtc cccacttggg acaactgggt
    14581 tgagacttgt aggagaagag ttgatttccc aatcccagga tccccaccga tgaggacgag
    14641 acttcctggt accactccgc ctccaagcac acggttgaat tcctccatct ccgtcttggt
    14701 tcgattgaca ttgatggaag tcacctcagc tagtttcatg ggcttggttt tctcacctgt
    14761 caaggacaca cgcgcattct tgacctcggc aacctcaacc tcttccacaa aagaagacca
    14821 agacccacag ttggggcaac gtcccagata tttaggggaa ttatacccac aattttgaca
    14881 tacaaatgtc gcttttttct ttgcgatgac aaacctcttt ctatatctct aactcacact
    14941 caatcacttg gcaaaaatca atcttctcat ttggcacaaa ctggcgcatg agcattcgat
    15001 gagcaacaac taccacagtc tgatgttctc gatacttaga catacattct agaaaccgag
    15061 acttcatttc cgtagctgtc tcatattgaa taggactatt aggaagcaac tcccccttgt
    15121 tttctaaaaa cagtcttcta gctgtttcaa agttttctat tcctgtttta tagacctgcc
    15181 attcatgtaa taaaggctct actcttaaag gaagacccgt agcacagacc acatacgaag
    15241 ccgtttctaa agctcttgtg actgcagaag atacgattat ttcagctgac gagagtaaag
    15301 gagttttgct caatttctgg acttgctgcc gtcccatctc agacaagggt gccaaatcta
    15361 tcccaaatcc tatataagaa cgctcctcta actcacggta atctggctcc ccatgacgta
    15421 caaagataat cttcattcta gtgccctgtc gatccaaatc caccagttcg aacgccatca
    15481 gctgcatctc catctgcaat taagaaagta gcaaaaacag cctggacaat acgttcccca
    15541 acttcaagaa caacctcttg gtctgtgata ttcttcatct gcgcaaaaat atgcccttca
    15601 tttccaggat ttccataata atccccatca atgaccccaa ctgagttaat taaaaccaag
    15661 cccttcttac gaggatttga agaacgatca tagaggtaga gaacctcagt cggctgcata
    15721 taagccttaa cccctgtcgg aaccaagaca atctctcctg gcgcaacaac tgtacgcaca
    15781 gcaaccttta agtcgtaacc agccgcatgc gctgtctcac gcttgggcaa taaattttca
    15841 tctgtaaaac tcgaaaccaa ttcaaaacca cgaattttca taattttctc ttttctatta
    15901 tcatttattc tagattattc tatcttattt attcggaaaa agcacgaaaa aagagcacac
    15961 aattcaaatc gcttagggct gctggattcc tcccctgacc cgcttcacgc agaactgttg
    16021 ctccactatt tattatatca cattcctatt cattttaaaa gcaaaattat tttttccgtc
    16081 tatttctaaa aaaatcctgc atgatagctg cgcattcatc ttccaaaatt cctatttcaa
    16141 cctccacacg atgattgaga cgctcatctg tcaagatatt gtacaaactc ccagcagcgc
    16201 caaatttctg gtttttagcc ccatagacca catttggaat gcgggcaagc ccaatcgctc
    16261 cactacacat gacacaaggt tcaatggtca caaaaagtgt gcaatccagc aagcgccagc
    16321 tctcctcact caagttcgca tcctctatag ccataatttc cgcatgcata accgctcgct
    16381 gtaattcctc acgcgcatta tgcccacgac caatgatttc cccatctttg acaatcacac
    16441 aaccaattgg aatttcatcg tgttcaagag caatctcagc ctctctcaaa gcctccctca
    16501 taaagacttc tttttcttca agcgtataat acatctcttt tctcttttcc tacttatcga
    16561 ttttattatt atatcatgaa tcccaacaca aaagaagcca ccgaatgcgg tgactctata
    16621 gggagattat tatgaaaaag aaaagtttag gatatttgtt acaacaagtt aggaggtctt
    16681 cttgtaaccg tctatagtat acccgaccta tcttaaacaa atcttaaaaa tctcttagga
    16741 ccaaacactt tctaaaatat ttgtttgttc acgaccagga cctactgaga aagtagaaat
    16801 acgaacgcca accaattcac tcacacgacg aacatagtta cgcgcattct caggaagatc
    16861 ttccaaattg cgaactccgg taatatcttc tgaccaacct ggcaactctt catagatagg
    16921 cttgcaacgt ttcaattgct caagactagc tggatagtag tcaatacgtt gaccgtcaag
    16981 atcataggcc acacagattt tcacagtatc caaaccgctc aaaacatcaa tagagttcaa
    17041 agaaaggtta gtaataccag aaacacgacg gctatgacgc atcacaactg agtcaaacca
    17101 acctacacga cgtggacgac cagttgttgt accatattca tgacccactt cacggatacg
    17161 ttctcccact tcatcaaaca actcagttgg gaaaggacca tctcctacac gactcgtata
    17221 agctttacat acacctacaa ccttgtcaat cttgcttgga ccgacaccag aaccaattgt
    17281 cacaccacca gctacagggt ttgatgacgt aacaaatgga taagtacctt ggtcgatatc
    17341 tagcataaca ccttgtgcac cttcaaaaag cacacgtttg ccattatcaa gcgcatcatt
    17401 caagataaca gatgtatcta tcacgtattt cttgatttgt tgaccatatt cgtaatattc
    17461 ttcaaaaata tcatcgaaaa caatcgcttt actgtcatac aatttttcaa aaagacgatt
    17521 cttttcagca aggttacgtt ctaaacgctc acggaaaata tctttatcta aaagatctgc
    17581 aatacgaatt ccaacacgag cagccttgtc catataagct ggaccaattc ccttaattgt
    17641 cgtaccaatc ttattgtcgc ccttagcttc ttcttgcaag cgatccaact cgatatgata
    17701 aggcaaaata acatgcgcac gatcagaaat acgcaagtta tcagttgtta caccttcctc
    17761 atgaagatag ctcaactctt ttacaagaga tttaggattt acaaccatac cattcccaat
    17821 gacagatatt ttttcaggga agaaaatccc agatggaatc aagtgcaact taaatttctt
    17881 accgtcaatc acaatcgtgt gaccagcatt atcaccacct tggtaacgtg caattacttc
    17941 tgcattcgct gaaaggaagt ctgtaatctt ccctttacct tcatcacccc attgggtacc
    18001 tacaacaaca actgaagtca taattttgtc tgagccctca ggctcttcct ttctcacata
    18061 catggcagga ctctcacctg caattatatc ttacaattta ttataataaa aaatcgcctt
    18121 tttatcaaga agaaacaata gaaagatttg ctatttccaa ctattaaaaa atgatttaga
    18181 aaaattacta gctatttact attatctttc cataaaagag taaattagtt cggaaattta
    18241 ctaaaattac ctcaacaaga aataaacccc cgattcatta ccaatttttc aagatacaaa
    18301 cgataagcaa cacgataatg gtaaacgata aaatccctac gacaaccaat gccatatctc
    18361 actaaataat aaattaaaaa tttaaaatga acatgttccc agtcaaaatt atcaccaaat
    18421 gtaggaccat actcttcttc aatactatca tagaaattag ccatctgctc ataaattttt
    18481 tgtaacataa tcaaatactc cttttctttt ttataaactt attctaacaa aaaattttac
    18541 acattcacta tcaattcctg aattgttaaa ataccagcct caacaagata aaaataggaa
    18601 aagttgacaa aatagaaaca aatttgctac ctaaatttca aacaattaaa gttctaaaaa
    18661 gaccgcctta aaacttttgg gtaaatccta ttaaaactat aatattttta tataggtatt
    18721 atggttctga ttttctagta taaaaaaatt ca
//
LOCUS       DAVLHM010000040        18606 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLHM010000040 DAVLHM010000000
VERSION     DAVLHM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.040"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..674
                     /locus_tag="VXE45_001614"
     CDS             <1..674
                     /locus_tag="VXE45_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0789625.1"
                     /translation="KRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFIK
                     ELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRYR
                     QNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYK
                     NLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYD
                     VGESL"
     gene            1358..1519
                     /locus_tag="VXE45_001615"
     CDS             1358..1519
                     /locus_tag="VXE45_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789626.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1611..3290
                     /locus_tag="VXE45_001616"
     CDS             1611..3290
                     /locus_tag="VXE45_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0789627.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3558..4124
                     /locus_tag="VXE45_001617"
     CDS             3558..4124
                     /locus_tag="VXE45_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789628.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4446..4634
                     /locus_tag="VXE45_001618"
     CDS             4446..4634
                     /locus_tag="VXE45_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0789629.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4696..5454
                     /locus_tag="VXE45_001619"
     CDS             4696..5454
                     /locus_tag="VXE45_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0789630.1"
                     /translation="MVVYIRQSKLPSEVSINKYHAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5512..6366
                     /locus_tag="VXE45_001620"
     CDS             5512..6366
                     /locus_tag="VXE45_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0789631.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6478..7362
                     /locus_tag="VXE45_001621"
     CDS             6478..7362
                     /locus_tag="VXE45_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0789632.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7501..7602
                     /locus_tag="VXE45_001622"
     CDS             7501..7602
                     /locus_tag="VXE45_001622"
                     /inference="COORDINATES: protein motif:HMM:NF014902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0789633.1"
                     /translation="MNTLGDKLMELSAIYHRPESEYAYLYKDKKLHI"
     gene            7666..9264
                     /locus_tag="VXE45_001623"
     CDS             7666..9264
                     /locus_tag="VXE45_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0789634.1"
                     /translation="MEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTE
                     GQNILYGDKGCVENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFAN
                     GNALLNPEGTLDWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSN
                     HKYNTTDYFEIDRYFGDKETFRELVDQAHHRGMKVMMDAVFNHIGSQSLQWKNVVKNG
                     EQSAYKDWFHIQQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATY
                     WIEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHA
                     VMNYPLSDSIKDYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWT
                     ANEDVQLVKSALAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNF
                     MKRLIKIRKYASVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEA
                     VALASNCQELENQLVISPDGFVIF"
     gene            9539..9994
                     /locus_tag="VXE45_001624"
     CDS             9539..9994
                     /locus_tag="VXE45_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789635.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            10439..10915
                     /locus_tag="VXE45_001625"
     CDS             10439..10915
                     /locus_tag="VXE45_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789636.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            10915..11676
                     /locus_tag="VXE45_001626"
     CDS             10915..11676
                     /locus_tag="VXE45_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV0789637.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSGENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            11704..12480
                     /locus_tag="VXE45_001627"
                     /pseudo
     CDS             11704..12480
                     /locus_tag="VXE45_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12408..12860
                     /locus_tag="VXE45_001628"
     CDS             12408..12860
                     /locus_tag="VXE45_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789638.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            13679..14038
                     /locus_tag="VXE45_001629"
     CDS             13679..14038
                     /locus_tag="VXE45_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789639.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            14048..14413
                     /locus_tag="VXE45_001630"
     CDS             14048..14413
                     /locus_tag="VXE45_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0789640.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            14400..16250
                     /locus_tag="VXE45_001631"
     CDS             14400..16250
                     /locus_tag="VXE45_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV0789641.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQKYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFTKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEENQKKYKVYIRETTSYFVYNK
                     EHSDKNQYIKGRTLIRQLTNDSRVIPYRRPTVERLQEKISEISLLIELTETDKKYQDI
                     KDNLVSEIAELDIKLTQTNEKIATLNKMAEVLINSKSEGSGSQKLARHEFSKLNMTES
                     TTLEQVNEELLKLQQEFGNVLDEYEKTIRKLGQLFKVFDECINKEIMNEI"
     gene            16506..17938
                     /locus_tag="VXE45_001632"
                     /pseudo
     CDS             16506..17938
                     /locus_tag="VXE45_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(18176..18310)
                     /locus_tag="VXE45_001633"
                     /pseudo
     CDS             complement(18176..18310)
                     /locus_tag="VXE45_001633"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         6645 a         2693 c         3767 g         5501 t
ORIGIN      
        1 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
       61 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
      121 gtgattttat aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
      181 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
      241 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
      301 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
      361 agatagagat agagaaagat atagagatag ataaagagag agagggagag atagataaaa
      421 agtccacccc cattttttat ggagaattca aaaatgtaag gttaagcaaa gaagaatata
      481 aaaatctaaa agaaaaatta aactcacaca cagatataat gataaataaa ctatccagat
      541 acatggaaag cagtggtaag acctatcaaa accactatgt gacaatctta aaatggtatg
      601 aagaagataa agacaaacta agacagaaag gtttaaataa aaaaatgaat tatgatgtag
      661 gagaatcttt atagataaaa agaggtggaa aggcactatt aaagacttta agtttaaaaa
      721 ggtatcaaag tatgccagag ataaaaaaat ataaatatga cactttaaag gcgattagaa
      781 aattaaagaa atgctagaag acttttagat gacagttacc aagagggtct aattttcact
      841 gctacttatg cagtaggaat tggacctttt tatataagca aattctattt caaaattggt
      901 taccaagaaa gacttctttt cactgttaag tataagaggg taatttatag aattttgtta
      961 catcaagata aatattttct gatggtcaaa ttttaaaaag attaataact ctcgataaat
     1021 tttgaacctt aacaattgaa tagaccaaga caagacgtta attatttttg gagcgtaata
     1081 acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg ctaagcaaaa
     1141 agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc cgctatgaag
     1201 aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata gaggcggagg
     1261 tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt aattaaacaa
     1321 ataattatta gatataaaac tttagaggag gtatatattg gacaatgact ggaatggatt
     1381 ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt tagataatct
     1441 acccgatcca acgccagcaa aaaatcaaga gatgaaaaat agttttgaca tggcaaaaac
     1501 acaaattgag acggactaat aaaagtgtta taatatactt gaaatgatag tccaaactta
     1561 aattaaaaaa attatatatg atatagaaaa attatattga ggttaatact atgtcaaaag
     1621 aaaaaataaa agtatacctc tatacacgag tatctacgtc aatacagata gaggggtatt
     1681 cgttagaggc acaaaaatca cgaatgaaag cttttgctat ttacaacgat tatgaaattg
     1741 ttggagagta tgaagatgcc gggaagtctg gcaagtctat tgaaggtaga atacagttca
     1801 atcgaatgat ggaagatata aaatctggaa aagatggagt atcttttgtt cttgtgttta
     1861 agttatcaag atttgcaaga aatgccgctg atgttctttc tacacttcag ataatgcagg
     1921 attatggagt taatcttatc tgcgttgaag atggcattga ttcatctaaa gatgctggga
     1981 aactaatgat ttctgtttta tcagctgtgg ctgaaataga aagagaaaac atccgtattc
     2041 aaacaatgga aggttgcatt caaaaagcaa gggaaggaaa atggaatggt ggctttgctc
     2101 cgtatggata taaacttgaa gacggcaagc tgtttataaa tgaggaagag gcagttgcaa
     2161 taagaacgat tttcgaccag tatgtaaata ctacgatagg agccaatggg atatctaaat
     2221 acttagagaa tcatggaatt agaaaaatcc caagacagaa tggtaagaat cctttgtttg
     2281 atgcaggtct tataagaaag atattaaaga atcctgtata taatgggaaa atagcatttg
     2341 gaagaagaac tttagaaaaa gttcatggta caagaaatga atataagcag gttgaacaag
     2401 atgaatatct aatatctgaa gggatacatg aagctatagt ttccgatgaa gtttggcaag
     2461 ctgctcaggt taagctaaaa tctcaagcaa agaaatatga gcatgtgaat aaaggaaaag
     2521 atacacgcac acacttgctt tctggaattg taaaatgccc gatatgtgga gtgggaatgt
     2581 ttgggaacaa gtgtatcaag aaaaagaaag atggcacaaa gtataaagat ttttattact
     2641 atggttgtaa acataggcag atgataagag gtcataagtg tacattcagt aagcaaatta
     2701 gagaagaatt gttagatgat gctgttgcag aggtgattgt caagatagta agtaatccga
     2761 aatttgcttc tatgatgcaa gaaaaaatca acatgaaggt ggatacctct gaaatagaaa
     2821 aagaaataga taattaccaa aaggaattga gaaagagtca ttctacaaag tttaagctaa
     2881 ttgaggaaat agataattta gatgttgaag ataagcacta taagagaagg aaacaggatt
     2941 tagatgatag actatatcgt atgtatgaca aaatagatga attagaatca tcactaattg
     3001 atgcgaaagc aaagaaacag actattgaag ctgaaaaact tacaggagat aacatatata
     3061 aggttctgat ctattttgat aagctctata aagtcatgaa tgatgtagag cgtaggcagt
     3121 taatttcagc tttgatttct gaaattcaag tttatgaaga aaaacaatct aacggacaat
     3181 ggctaaaatc cattactttt aagctaccaa ttatagaaga aaatctcaac atagatttgg
     3241 acaatgatga acaagttgaa tgtgtaagtt tattagagaa acgtagttaa tcctcaaaag
     3301 gttccccaaa ctttttgagt cccactgacg catcacgctg aggcggtatc actgcttgta
     3361 cgagttgaag catcagcgaa gtaaaagtag atgttcagcc aatgcgacga ggtgagaccg
     3421 aaggtcgata aggtgtgttc tgggtatagg actcgtaaag taagtaggaa atatgatgag
     3481 atgatacaga gagcctgaat tggtcaggtg acgtgcttat ttacattagc ctgataatga
     3541 aaatggagag attatcgatg gttatattgg aattgtacca aaatgattat tctaaagatt
     3601 tagtagcatt tgattccata gaagatggga aagcctttgt ggctcaaatc ccgggataca
     3661 ctctggaaac agaagatggt tttgaagtgg agtattttaa tcctaaaaac ataccggatt
     3721 atatggaaat tatttttaac ggaaatattg ttcctttatc taaatttatg ttcgatcctg
     3781 aggaaaatgt aaacattatt tggaaagaga tttcaaattt atccctcaaa aatgatagag
     3841 tgatcgaagg atattcaaaa attgatgcat atgtcgttaa caaccatgaa gttaaagcct
     3901 atgtcgaaac aagagaaacg aactatcgta aagcaaaaga cttcttagaa agccgcggat
     3961 atgaaatcga cagaagcttt ttcggaagtg aagacggtga agcgattctt tacagaaaaa
     4021 aagggatcga agtttggcat ttcttgtgtc acttagaccc aatgtttgta gagattgaag
     4081 atgtagaagg atatgttaaa gaagaagttg gagagattca atagtcaacc aaagttcctt
     4141 gtgagtatat acctttgcta gtaaaagagt caaaacgtta taacgaaggg ggggaagaaa
     4201 acccttgagt gtaagtcttt ttcttgttta gagggaaagt attagagtag ccgctcataa
     4261 tttatactag atttgataac tgatttgaga cagattttat ttctataaat attgtgaaaa
     4321 ttttttaata ccaaagattt aaagttactg tgttaaaaat cctctccact tttaaactaa
     4381 tgtattataa aagccagttg acacaagtgt tacacctgtg atagaattaa cttgaggtga
     4441 tgaaaatggc aaccgataaa aatagaataa tgattagctt ggatgataaa aatctagaga
     4501 aacttgaaaa tttagtagaa gatgctagag atagaagggg aatgcgacta acaaagtccc
     4561 aggttattga attactccta aataccgttg attatttcga tgatattatg ggggctattt
     4621 actcaaaaaa ataagagcaa aattgctatt attttttaca aattggtgta acactagtga
     4681 tataggagtg atgaaatggt tgtttatatt agacaaagta aattaccaag tgaggtttca
     4741 attaataaat accatgctca agtaggtgcc tacttacaag gagaagaagc tgttttatat
     4801 caatcttttt ctgaaataaa agagttaaca agtgaagata tagttgtaga ttatataatg
     4861 gagactagag cattactaaa aatgatgggc ttaaacgttc cggttcatga ctatcctatt
     4921 gagcttaaag agttttatgg tcgaaagatt tatgctggta ttttaggaga gattgtgaat
     4981 atacctgata attggggaaa atttattaag cctaaagctg gttcaaaagt ctttactgga
     5041 agagttgtta atggaaccca tgatttaata ggtattggtc tacctttcga ctatcctata
     5101 tggattagtg aggttgtaga attcatagct gaatggcgtt gttttgtgtt agatggtcgc
     5161 gtattagatg ttcgacccta tacaggtgat tatcatgcac aatttgatgc aagtgtaatt
     5221 gatgaagcga tatcatgttg gaaagatgcg ccaatagctt atggactaga tatcggtgtt
     5281 actcgcgatg gcagaacact tgttgttgaa gtaaatgatg gttatgcatt gggaaattat
     5341 ggcctatctc ctttaaaatc aatcaatttt catagagcta ggtggaaaga aatggtaaaa
     5401 ccctattttg aaaaaaatga aatttttaaa atccaacagg atgttgtttt ctaaaataaa
     5461 tatggtatat aaccaatata aaaagcatca aaatgaacaa ggaggaatct gatgcttgga
     5521 gcaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa aacaaaggac
     5581 tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac ctgtgctgtt
     5641 gcagaagcaa ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat gaagaaatat
     5701 ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct aaacagcgat
     5761 aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc tccatgtgct
     5821 tggatcatgg actgtggttt ttatgcgaaa actggtatgt ggccatcatc tagaggactt
     5881 acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg cgctatggct
     5941 acagctgatg ctatctttct atgtcgtttt tactttggtg gttattgtag agagtacgag
     6001 caatcaatta acgacaatcc tacagagtgt aaaagacgaa ttaaggatta tatagaaaaa
     6061 gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta tcgttttaac
     6121 gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag tagagacttc
     6181 gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct cgcagcaatc
     6241 acttgtaaca tagcagaggc agcttacggt attcctgatt ggatcaagga taaggcctat
     6301 tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag aataaaagcg
     6361 tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata ataggattac
     6421 atttacttgc atacgacgaa atgtaaacat ttctgtttaa aattaaggat aaaatcaatg
     6481 aaaaaagtaa tggtaattat caaccctact tctggtggcg agaaggcttt ggattacaaa
     6541 gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa aattaccgaa
     6601 aaagcgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta tgatgcagtg
     6661 gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga tgagagagac
     6721 tacattccta agttagggat tatcccaggc ggtacgggta acctcattac aaaacttttg
     6781 gaaatcaatc aagacatcga tggcgcaatt gacgaactgg attttgattt aaccaataag
     6841 attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat cggttctctg
     6901 cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat tttaacctat
     6961 gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa ggttgagaca
     7021 gaaaatggaa attatgttgg tgaagctagc catgttttgg tccttttgac aaattacttc
     7081 gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt gattctgaaa
     7141 gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg ggatgttgtc
     7201 gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc agatagtgaa
     7261 ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat caaagtccta
     7321 gctcagcgag tagaagtatt ttcaaaaccg aaagaggatt agtatataga gaaagccttt
     7381 tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat tccttgcaaa
     7441 tagtttacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg taaaatttga
     7501 atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatag gcctgagtcg
     7561 gagtatgcct atctttataa ggataagaaa ctccatattt gaattcgaac taagaaaggg
     7621 gacattgaaa gcatcaactt gcactatggg gaccctttta tctttatgga ggagttttat
     7681 caggatacaa aagaaatggt caagataact tctggtacct tatttgacca ttggcaggtt
     7741 gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga tacagaaggt
     7801 caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa tcttcatgca
     7861 attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa ggttcctgac
     7921 tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa tggcaatgct
     7981 ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa gagcgatgat
     8041 ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca agacttgggt
     8101 attactggac tatatctttg tcccatcttt gaatctacaa gcaatcacaa gtacaatacg
     8161 acagattact ttgaaattga ccgttatttt ggagacaagg agacctttcg ggaactggtg
     8221 gatcaagcgc atcatcgtgg catgaaagtc atgatggatg cggtatttaa tcatattggt
     8281 tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggcg aacagtctgc ttataaggat
     8341 tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa gagagactta
     8401 ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc caatccagag
     8461 gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa tatcgatgct
     8521 tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt tcgtaaggca
     8581 gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac atctcagcct
     8641 tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctga tagtatcaag
     8701 gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat caatggagag
     8761 tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga ttcacatgat
     8821 acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc agccttagcc
     8881 tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagct agccttgact
     8941 ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc aagtgacaat
     9001 gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc agtaatcatt
     9061 tcgcatggca agtatagcct tcaagaaatc aaatctgatc tagtagctct ggaatggaaa
     9121 tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta tcttttagag
     9181 aaagaagcag tagcactagc aagcaattgc caagaattgg agaatcagct tgtcatctct
     9241 ccagatggat ttgtgatttt ctaaaaacta gttgatgaag attatggtac atttcatatc
     9301 ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa tgaattgtag
     9361 aggacatgaa acaagacaaa gaattgttag agattttgaa gtttagccta aagcacatat
     9421 taagctgtta gcaaatcaac aaaaacatag tgatgcagga gcaactattg aagatgaata
     9481 ttatgtattt atcgctgaga gtaaaattga tggcaagaag gaagttattc agtgttgcat
     9541 gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc tttttaatcc
     9601 gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag ggagtggaaa
     9661 tttacaacct gaaaagtgga atgaaactgc aaagcagctt tataatgcta taatgtggtt
     9721 gattatttta tggaatgcta agccggatac acctttattt aattttaaag acgaagtaat
     9781 taagtataaa acatatgagc cttttgaaag cagtataaaa agagtaaata ctactataaa
     9841 gaatggtagt aaagggaaaa ctctgactga gatgattaat ggctacagag cggataacga
     9901 tattagagat gaaatttgta actttaatat tctgaaaaat aaaattcgtg atatgaaaga
     9961 ccaacaagga aatacaatgg aatcttactt ttagttattg ttgaattttg ggtattctat
    10021 aaaatatcct aattgagatt taaatagtag actatacaat atagttaaaa tatcagtaaa
    10081 aacaacactt tattgaggta ttggatacgc tttgctaata gcctaataat cacatgtgga
    10141 gtgttgctac aacgaaaaag gtgataatcc ttaatttcaa gctattttat aagcattttg
    10201 tctttgtaga taaaggcaat tttgacaata aaaatcctaa aaggtgaatc gttatagatg
    10261 tatttgtaga tattgtttgc gcatcgaaaa aattaataca agaataaata tttatagctc
    10321 tttaggtgac ttttatagaa gtaaagttta ggatagaaaa acaagaaata acgcaccatt
    10381 tttggtgcgt tatgcttttt tatgctataa tggatttata aaaataaagg agtttgctat
    10441 gattggaaag aacataaaat ccttacgtaa aacacatgac ttaacacaac ccgaatttgc
    10501 acgaattata ggaatttctc gaaatagtct gagtcgttat gaaaatggaa cgagttcagt
    10561 ctctaccgaa ttaatagaca tcatttgtca gaagtttaat gtatcttatg tcgatatcgt
    10621 aggagaagat aaaatgctca atcctgttga agattatgaa ttgactttga aaattgaaat
    10681 tgtgaaagaa agaggtgcta atctattatc tcgactctat cgttatcaag atagtcaggg
    10741 aattagcatt gatgatgaat ctaatccttg gattttaatg agtgatgatc tatctgactt
    10801 gattcagaca aatatctatt tagtagaaaa ttttgatgaa atagagagat atagcggcta
    10861 tttggatgga attgaacgta tgttagagat atctgaaaag cggatggtag cttaatggaa
    10921 atccaagatt atactgatag tgaattcaaa catgctttag caaggaatct tcgttcactg
    10981 acaagaggaa aaaagtccag taaacaacct atagcgattt tgcttggagg tcaaagtggt
    11041 gccggtaaga ctacaattca tcgtattaaa cagaaagaat ttcaaggaaa tattgttatc
    11101 atagatggtg atagttttcg ttctcagcat ccacactatt tagaactgca gcaagaatat
    11161 ggcaaagaca gtgtagaata taccaaagat tttgcaggaa aaatggtaga gtctttagta
    11221 acaaaattga gtagtttgag atacaatctt ttgatcgagg gaactttacg aacagttgat
    11281 gttccaaaga aaacagcaca actcttgaaa aataagggat atgaagtaca attggcctta
    11341 attgcgacaa agcctgaatt gtcgtatcta agtactctta tccgttatga agaactgtac
    11401 attatcaatc caaatcaagc acgcgcaact ccaaaagaac atcatgattt cattgtaaat
    11461 catctagttg ataatacacg acaattggaa gaactggcta tctttgaaag aattcaaatt
    11521 tatcaacgag atagaagttc tgtatatgat tcaggagaaa atacaacttc agcagcagat
    11581 gttcttcaag agttactgtt tggggagtgg agtcaggtag agaaggagat gttgcaggtg
    11641 ggggaaaaga gacttaatga attacttgaa aaataaacaa ttgatatttt taggagagta
    11701 gaaatgagag ggtttaataa caagataaag tctgtttatc aagaactaac aaattccaaa
    11761 gagaaattcg gtagctttca caagacttta attcatttgc atacacctgt ttcttatgat
    11821 tacaagctat tttctaattg gactgcaacg aaatatagaa aaattactga agatgaacta
    11881 tatgatatat tttttgaaaa taagaaaata aaagttgata agacaatttt tttagtaatt
    11941 ttgataaggt tgttttttct agttcaaaag aatatattag ttttcttatg ttagcagagg
    12001 caatcataaa aaatggaata gaaatagttg tagtaactga tcataatact accaaaggta
    12061 ttaaaaagtt acaaatggca gtctcaatca taatgaaaaa ttatccgatt tatgatatac
    12121 atcctcatat tttacatgga gtagaaatta gtgcagcaga taaattgcat attgtatgta
    12181 tatatgatta tgaacaagaa tcatgggtta atcaatggtt aagtgaaaat attataagtg
    12241 agaaagatgg aagttatcaa cattcactga ctataatgaa ggatttcaat aatcaaaaaa
    12301 tagttaacta tattgctcat ttcaatagtt atgacatttt gaaaaaaggt tctcacttat
    12361 caggtgcata taaacgaaaa attttttcta aagaaaatac acgatttttg gagtttaata
    12421 ttaactcgaa agaatcttcg caacaacttg atattctcta taaagaagtt ggtgtattaa
    12481 gtttgggaca aaaagttgta gccatgcttg attttttatt agcatatagt gactattcta
    12541 aagacttcag accattgatt attgatcagc ctgaagacaa tctagacaat cgttatattt
    12601 acaggcattt agttcagcag tttagagatg tgaaagctca acgtcaaatt attttagcaa
    12661 cacataatgc tacaattgta acaaattcta tgacagatca agttgttatt atggagtcag
    12721 atggagttaa cggatggatt gaatcacagg gatatgttag tgaaaaatat ataaaaaatc
    12781 atatcatcaa tcaattagag ggaggaaaag attccttcaa gcataaaatg tctatatatg
    12841 agacggcttt atcagagtag agtcagaaaa agtaggttag aaatttagcc tacttttttc
    12901 tttgttcgac aggcatagtg tacatctgag gtccaagtcc tctgtggata tttgctgcag
    12961 atgaaaccaa tagcgactcc taagcctgaa tatcgtgagg taggggggat aggaaggaat
    13021 tagcgaaatc aaggttctac aaacagaatc gtgacttgaa gccatatata gcggatgagg
    13081 aactctaaaa tccaaatagg tgtcgtaacc tatatacgta aattacgaga gtaaactagg
    13141 aaagatgtac ggcttattcc gtgagcgttt aggacgtagt acaacgaatc atgggagtca
    13201 gctgaacaca tagtattgaa gaaatttctg taatggaaat ggagcgaaga agtgaacaat
    13261 taaatgaata cctctctaat taaatttgtc aattctaatt cctggtatga aaagacagtg
    13321 acctaaaaat gtaaacgatg ggagctgatc ataaatatag gacggtacat gcagtggtgt
    13381 tagagattag tccctacttg atttgtgata acttccccaa ctttcttctg ctatactttt
    13441 ctcaactttt aaaaatccaa ctaagaattt tacctgggag tttgggggcg tagccaccaa
    13501 gttatcttat ggttagctgt caaaactgga aggttttggt tagctggcga tatgattttt
    13561 tgggtattgt gaccacaatg cctgagctcg caaagaccga acaaggactt taagaaattt
    13621 cccgtatgac acacggggtc ggggtttacc cgagaaagga tgaaagtgag gaaaagagat
    13681 gtctgaacag taccgtgaca ttcgaaaaga ggtaaatcta accgcagatg agctaaaaca
    13741 gattgaaaaa atgatggagg ttgataatta tcgtcacttt tcaccattcg tcagggataa
    13801 aattttgatg actgatgaca aacagttagc tgccaaagaa tggttttccc tttggcagtc
    13861 tcaaaagttt gaacagatca gtcgagatgt gcatttggtt ttgattatcg caagagagaa
    13921 tcaccaagtg actcaagaac acgtgtcaat cttattgacc tgcgttcaag aattgattgc
    13981 ggaagtcaat caagtacagt cactcagtcg tgggtttcgt gaaaaataca tgagatagga
    14041 ggctactatg gtttatcgtt atcgtaccaa tctcaaaaaa gtatttctaa cagattcaga
    14101 attacaccaa ttgaatgaac ggattgctaa gagcaattgt caaaattttt cagtctatgc
    14161 cagaaaagtt ttgcttaatc ccaatatgtc atttgtcacg attaacacgg atacttatga
    14221 ccagttagtt tttgaattga gacggatcgg aaataacatt aatcaaattg cgcgtgctat
    14281 caatcaaagc cgtctgattt ctcaggaaca gttacaagaa ttgagtaaag gagtcggaga
    14341 gttgatcaag gaagtggaca aagaatttca agtggaagtg aaaagattga aggagtttca
    14401 tggtagtcac taagcatttt gcgacacacg gaaaaaaata tcgtaggcgt ttaattaagt
    14461 atatcctcaa tcctgataaa acggacaatt tgaaattagt atctgatttt ggtatgagca
    14521 attacttaga ctttcctagc tatgaagaaa tggtagaaat gtacaatgtc aactttacca
    14581 ataatgacaa gttgtacgaa tacagaaatg accgacaaga aaaacaccaa caaaatattc
    14641 atgcccatca cctcattcaa tcattttctc ctgaagataa tctgacacct gaagaaatta
    14701 accgcattgg ttatgagacc attatggaat taacaggagg ccgttttcgt ttcatcgtag
    14761 cgactcatac agacaaagat catattcata atcacatctt aatcaacgcc attgactgta
    14821 attcagataa aaagttgata tggaattatg ccttggaacg aaaccttcgt atgatttcag
    14881 accgcatttc taaaatggct ggggcgaaaa ttattgaaaa gcgtttctct taccgtgact
    14941 atcaaaaata tagagcgact agccataagt ttgaactaaa gcaacgtctt tattttttga
    15001 tgcagcagtc aaaatccttt gatgattttt tagaaaaagc agagcaatta catgttcata
    15061 ttgattttag tcagaagcat agtcgattca tgatgacgga tcgggcaatg acaaaaccaa
    15121 ttcgaggacg tcaactcagt aaacgagatt tatatgatga agattttttt agaatgcatt
    15181 ttaccaagca agagattgca agtcgtttag aatttttgtt gaactgtgtc aattctttag
    15241 aagggttact aacaaaatca aaagaattga atctaaccat tgacttaaaa caaaaaaatg
    15301 taatctttat acttgaagaa aatggaaagc aattcagtct gagtcataaa aaaataagtg
    15361 atgagaaatt atatgatgtc aatttttttc aagattattt taaaaataag gaagtaggtg
    15421 tttcagaagg aatagaaaat ctacaggcac agtaccgtgc ttttcaagaa gaacgagata
    15481 aggagaaggt atctactgaa gaaattgagg aagcctttga gacatttaag gaaaaacgag
    15541 atgccgttca tgaatttgaa gtaaaactta cagaacacca aattgagaag ttagttgatg
    15601 aggggattta tatcaaagtg tcctttggta taaatcagag tggtcttatt ttcattccta
    15661 actatcaact ggatattatg gaagaagaaa atcagaaaaa atataaagtc tacattcgtg
    15721 agacaacctc atattttgtc tataacaaag aacattcgga taagaatcag tatatcaaag
    15781 ggagaacctt gattaggcag ctaaccaacg atagtcgagt aataccatac agaagaccga
    15841 ctgttgaaag acttcaagaa aagatttctg agattagcct cttgattgag ttaactgaga
    15901 cagataagaa ataccaagac attaaagaca acttggtttc cgaaatagca gagctagata
    15961 taaaactgac tcaaacaaat gaaaaaattg ccaccttaaa taagatggcg gaagtactta
    16021 tcaattctaa gagtgaaggt tcgggtagcc aaaaactagc taggcatgaa ttttctaaat
    16081 tgaacatgac agaatcaaca actttagaac aagtcaatga agaacttttg aagttacaac
    16141 aggaatttgg taatgttctt gatgagtatg agaaaacaat aagaaagctt ggacaattat
    16201 ttaaggtttt tgatgagtgt atcaataaag aaattatgaa tgaaatataa atcagactga
    16261 agacaaactc aaattttttt ggatatcttt tctgtttatg gttgccaata tcggtttaac
    16321 ttctaaaaca aacattaata aaaatgcatt caaagacgat tttacctatt ttacgattac
    16381 gcttcgaccc caaatcatta aagttgtcta tgctctatca ttgcatcact ggacttgtca
    16441 agagttaaga taattcggag tccactgaaa aagtcatcgt atgatggtat actaaagatg
    16501 aggtgatggt atgcttgata atcgatgtta gtccctattc tactctgtgt gatattgttg
    16561 ttcccaaaac tcatttttta cgacagctaa tggaactctg tgattttagt tttatttatg
    16621 acgagctgga aaagaattat caacctgact tcggatgtcg ttcctactct ctccttatca
    16681 tgatgttcaa gtatctctta ttaaaagaca tctataagtt gtccgatgtg gatgtggtgg
    16741 agcgctcctt ttctggtatg accttcaaat acttccttgg tctagctcct gttattgaac
    16801 cgtcctcatt gactaaattc cgaaaacttc ggaacaaaga tgaacgatta cttgatttgc
    16861 tcatcgctaa atctgttcag attgcgatag agctcggtct gattaaaagt aacattctca
    16921 ttgtggatgc gactcatacc aaagttcatt acaatcacaa gaaacctcaa gaagtcctcc
    16981 gagaacgctc aaaagccttg cgtaaaacga tttatcagta ttcggaatat atcaaggcag
    17041 aatttcctag taagcctcag gaagatactc tagtagctga attaagatat acacaagaag
    17101 taatatcagt ccttgagaag catgacgaat tgactggaat accagctatc tcacaaaatt
    17161 caattacctt aaagaagctg tagaggatga cttagagcac ttggaatcct ctgtcaaaga
    17221 agaagcaaga attggacata agtcagccga tagttccttt tacgggtaca aagagcattt
    17281 tgccatgacc gatgaacgga ttattactgc ctgtgtggtg acatcgggtg aaaaaagtga
    17341 tggtcctgtt ttagaagaac tctatcacaa atctaaggat aatggcgtga cgattgaagc
    17401 tattgttgga gatagggcct actctgggaa ggataatatg caatttacca agaaagaacg
    17461 tgtgcattga gtcgctaggc catatccaac tatttcaaaa ggctttcgta ggaaggaaga
    17521 tgagtttttc tataacaagg acgcaggtct ctttgtttgt ccagaagggc atatggcact
    17581 aaagaaggaa aagacaggaa gaaggacggc tcaggaaacc cactattttg acatcaagca
    17641 ctgtcaaata tgcccttcaa aagtgggctg ttataaagaa ggggctaagt ctaagactta
    17701 tttgataccc cttaagagcg atgaacatat tttccagaag aggtttcagg aagcgcccta
    17761 ttttaaagaa aaggccaaac atcgctacaa gatagaagcc aaaaatgcgg aacttgaaaa
    17821 cagacatggt cttaatgtag ctagagcacc aggtctttta aacatggagt tacaagccgc
    17881 cacaaccata tttgtggtta atatgaagag gattataact ctaataaacc aaaaataagg
    17941 aaaagcaaag aggaatctat ccaagcagga gatagatccc tcttttttca ttttagttga
    18001 actgtagagc ttactttttc agtggactcg atgattagtg actatttttt tcaaactcta
    18061 ttagttattg gtaccctaat gccgaatgga gatatttagg attgtaatag atttcaatat
    18121 atttaaagat ttcgttcaat agttgcgaaa ttggcatcat tgacaagttc tctttttatg
    18181 ttttgtaaaa ggattccatg ggtgcattat catatggatt gccttttcga ctcaggctag
    18241 acttgcatct tttctgttta aggagttctt gaaatctagc tccagtatat tgagatcctt
    18301 gatcggtatg gccgactagt tcttatttga gattttctct atgataagct tgattgaaaa
    18361 cattcgttac caacttatct tgcattcgat ttcccattgc ctaaccaaca atttttctgc
    18421 tataaacata tatataatga taaataaaga gtacctgctt ttgtcggaat ataagttaaa
    18481 tcccccagcc agatttcatt tttacctttt gtttgaaaac actgattaat caaattgggt
    18541 cgtgttaatg aggaatgccg acggctatag tacttgtatt tatagcggat tcctttagca
    18601 tagaga
//
LOCUS       DAVLHM010000041        18506 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLHM010000041 DAVLHM010000000
VERSION     DAVLHM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.041"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..942
                     /locus_tag="VXE45_001634"
                     /pseudo
     CDS             1..942
                     /locus_tag="VXE45_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1070..1273)
                     /locus_tag="VXE45_001635"
     CDS             complement(1070..1273)
                     /locus_tag="VXE45_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789642.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1266..2348)
                     /locus_tag="VXE45_001636"
     CDS             complement(1266..2348)
                     /locus_tag="VXE45_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0789643.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2474..3256)
                     /locus_tag="VXE45_001637"
     CDS             complement(2474..3256)
                     /locus_tag="VXE45_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0789644.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3256..4599)
                     /locus_tag="VXE45_001638"
     CDS             complement(3256..4599)
                     /locus_tag="VXE45_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0789645.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4711..6027)
                     /locus_tag="VXE45_001639"
     CDS             complement(4711..6027)
                     /locus_tag="VXE45_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0789646.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6221..7447
                     /locus_tag="VXE45_001640"
     CDS             6221..7447
                     /locus_tag="VXE45_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0789647.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7646..9220
                     /locus_tag="VXE45_001641"
     CDS             7646..9220
                     /locus_tag="VXE45_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0789648.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9484..10272
                     /gene="codY"
                     /locus_tag="VXE45_001642"
     CDS             9484..10272
                     /gene="codY"
                     /locus_tag="VXE45_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0789649.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10272..10847
                     /locus_tag="VXE45_001643"
     CDS             10272..10847
                     /locus_tag="VXE45_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0789650.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFSPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10929..11014
                     /locus_tag="VXE45_001644"
     tRNA            10929..11014
                     /locus_tag="VXE45_001644"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10963..10965,aa:Leu,seq:aag)
     gene            11297..12427
                     /gene="ugpC"
                     /locus_tag="VXE45_001645"
     CDS             11297..12427
                     /gene="ugpC"
                     /locus_tag="VXE45_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0789651.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12574..12720)
                     /locus_tag="VXE45_001646"
     CDS             complement(12574..12720)
                     /locus_tag="VXE45_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789652.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12928..13686
                     /locus_tag="VXE45_001647"
     CDS             12928..13686
                     /locus_tag="VXE45_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0789653.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13773..14285
                     /locus_tag="VXE45_001648"
     CDS             13773..14285
                     /locus_tag="VXE45_001648"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0789654.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14467..15411
                     /locus_tag="VXE45_001649"
     CDS             14467..15411
                     /locus_tag="VXE45_001649"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0789655.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            15420..16097
                     /locus_tag="VXE45_001650"
     CDS             15420..16097
                     /locus_tag="VXE45_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0789656.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLIKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            16195..16953
                     /locus_tag="VXE45_001651"
     CDS             16195..16953
                     /locus_tag="VXE45_001651"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0789657.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16991..18496
                     /gene="lytC"
                     /locus_tag="VXE45_001652"
     CDS             16991..18496
                     /gene="lytC"
                     /locus_tag="VXE45_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0789658.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT         5626 a         3333 c         4093 g         5454 t
ORIGIN      
        1 cgtcttcaag cagaaaatga gtacctgaga gcggagaatg ccatcctaaa aaagttaaga
       61 gaactccgat tgaaggagga aaaagagaaa gaagaaagac agaaattgtt caagaattaa
      121 tgactgagtt ttcgttagct cttcttctaa aatccattaa actagcttgt tcgacctact
      181 actatcactt gaaacagcta gacaaaacag ataaggacca agagcttaaa gctgaaattc
      241 aatccatttt tatcgaacac aagggaaatt atgcttatcg ctgtattcat ttagaactaa
      301 gaaatcgtgc ttatttggta aatcataaaa gagttcaagg cttgatgaaa gtactcaatt
      361 tacaagctaa aatgcgacag aaacgaaaat aaaggagacg ttggtaagaa ggcagagaat
      421 ctcattcaag gccaatttga aggctctaaa acaatggaac agtgctacac agatgtgaca
      481 gaatttgcca ttccagcaag tactcaaaag ctttacttat caccagtttt agatggcttt
      541 aacagcgaaa ttatcgccta taatctttct tgttcgccta atttagaaca agtacaaaca
      601 atgttggaac aggcattcaa agagaagcac tacgagaata cgattctcca tagtgaccaa
      661 ggctggcaat atcaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
      721 tctatgtcac gcaagggaaa cagccaagac aacggtatga tggagtcctt ctttgggatt
      781 ctgaaatccg aaatgtttta tggctatgag aaaacattta aatcacttaa ccaattggaa
      841 caagccatta tagactatat tgattactac aacaacaaac gaattaaggt aaaactaaaa
      901 ggacttatcc ctgtgcaata cagaactaaa tccttcggat aaattaattg tctaactttt
      961 tggggggcag ttcattctac acccactatt atgcgtttta ttgtgggaag attttcctca
     1021 ttttctagtg aaattgaact ttttctaaca tcttttgata gatgacttct taatcaatta
     1081 tcatttccat tgttgtttct tggggtttca tcccttgtct ttgataaaag cggagagcac
     1141 cctcgttatc attccagaca cttagggtta gattattgca gccaatttct ttagcataat
     1201 agcagaaaaa tgacaataaa atagccccta gatattttga aaggaaagca taggggctat
     1261 atagtttaat caaaataaag caaatctttg ctggtgcttg taaagaggtc gaagccatcc
     1321 ttggtaacaa caccgcagtc ttcaatacga acaccgactt taccagggat atagatacct
     1381 ggttcaacag agaagcacat gccttcttcg atgaccatgt cgtttccttc catgatagat
     1441 gggaattcat ggacatccat accgatacca tgcccgagac ggtggttgaa gtactcacca
     1501 taaccagctt tttcgatgat ctcacgggca gcgcggtcca cttcatgagc agtcacacct
     1561 ggcttgataa agtcaagagc agcttgttgg gcttcaagag tcaagttgta aatatctttc
     1621 ttgaattggt ctggtttgcc gacagcgact gtacgagtca tatctgacgc atagccattg
     1681 accagaaccc ccaggtcaaa gaggagaaga gcatcatttt caaccttatt agctgctgga
     1741 atgccgtgtg gattcgcagc attatcacca gtcaagacca tggtatcaaa gctcatttcg
     1801 taaccttcac gtttcatggc aaagtcaatt tgtgcgatga tatctgtctc agtcttatca
     1861 agagaaatat tgtcaaaacc aacatgaaca gccttgtcag cataaagacc tgcaaccatc
     1921 attttttgta cttcatcagc tgatttgatg aggcgcatgc gttggatacg aggagtgagg
     1981 ttttcaaact cagcagtttc aaaaattgtt ttcaaaccat ggtatttggt caagatgaga
     2041 ttgtcaaact caacagcgac acgtttgaag tcaagttgtg gaagagcatg tttgattttt
     2101 tgccatggat tttcagaatc gacatagccc actactggga aggaaacggt gctacttgca
     2161 cgttctactt caagagctgg gacaaagagg agaggttcct gatccgctag gacaaagagg
     2221 aacatttggc gttcatgggg atcactgtaa aaaccagtga ggtaattgat tgtgacgggg
     2281 tcagatacga cagcgacgtc tagtttttct gattcaagat atgttaggat ttgttgtaat
     2341 ttagacatat gctaccttct ttctacccct ctattttggc aaaaaatgag agaaaatgca
     2401 agggagaagg gtaaaagaaa agacaaaaaa ctccgacaag ataacggagt tctttgatat
     2461 cattttcctt tgtttaagaa aagtcagcct tgcttttgac gtcactgtac tcttcagcga
     2521 tttcttggct gaggatatcc tcataggcag ggagttggat atcctgacca tatttcttct
     2581 tgagggcagt agtaactagg cgataagcca gattggcatt acgagagagg ataggcccgt
     2641 ggaagtagga accaaagaca ttcttataat gaaccccttc accgaccttt tcttcgttgt
     2701 ttccatttcc atagacaacc tgtcccagcg gtttttggtc atcagagagg aaggtacgac
     2761 cttggtgatt ttcaaatcca tagtaggttt catcgaaatc ttcattgtga atcttgatgt
     2821 caccgataaa acggttattg gtctggttga gcgtgtagtg tcccatgacc cctagccctt
     2881 cgatacgttt tcctgaagct tcaacataat attgacccaa tagttggaaa ccaccgcaga
     2941 tagccagaac tacaccgtcg ttttggatgt agttgtcaat gctctctttt ttagcaggta
     3001 ggtcgtctgc aatgatactt tgttcaaagt cttgaccacc accgaaaaag gcgatgtcgt
     3061 agtgattttc atcaaagtca tcatggagag aaacgatgtc aacggtcaca tgggctccca
     3121 gtttttcagc cacatacttg agcatgagga tgtttccatt gtccccgtag gtattcatga
     3181 gatttccgta gaggtgggca atgttgagct gataggggta attgccatct tttgaggaaa
     3241 gtgaagtata aaccattagt tcatctcctt tctaacaatc tgacgactag ccagcagttc
     3301 acgaaattcc agcatggcag tataagttgc cagaatatag gcatgcttgc agtcttgatt
     3361 ctcaatggtc ttgagaactt gctccagatt actcgtttca gtgattttct cagctggata
     3421 gccagtcact cggaggcgac gagcgatttc agaatgacga acaccgccag cgttgatttc
     3481 aggaatgtcc atgtcagtga tttgttcaaa gtctgcatcc cagatccagc tagtgtcaat
     3541 tccatctgca tagttggcat taaggaggac agataggcta aatggataag gtgctagttt
     3601 gatcatttcg atagcttggg ttgcaccgac tggattttta atcaagacaa gggtacattc
     3661 cttgtcaccg atatgaaagg tttcttggcg tccaaagaca gcacggctct tgtcaaatcc
     3721 ctgtttgatg agttgcgaat cggcacctag gaaacgggcg atggccacag cagctagggc
     3781 gttatagata ttatagagcc cgccgatttg gataccgtat tcttggccgt ctatgacaaa
     3841 gcgagagcga ttgttggtca actcaaccag ttttgtcaaa cgatagtcga gatcaggacg
     3901 tttacatcca caaccttcac agatataggc acccaagttt gcataggtat tatgctcata
     3961 tttgaggatg ccttggcagt caggacagag aatcccttcg gtattgtagt gagccagttg
     4021 ggctggtccc ttttccaagt caaaaccaaa atactctata gggtttggaa tagttggctt
     4081 gtagaaaagt ggactgtctc cgttaaggag aacagtagca gttggaactt tccgaatggc
     4141 atccaatatc atgttatagg tagtatagat ttcaccgaaa cggtccatct ggtcacggaa
     4201 gatattagta atgacaaaaa gactaggctg gatatagtca cagatacgag atagactggc
     4261 ttcgtcaatt tcgaggacgg caatattttt cccagtttta gaagatttgg ctgttaggaa
     4321 ggttgttgca atccctgtaa tcatgttggc accgcttggg ttggttagaa cttgaccata
     4381 aacctctttt aaaatgccga cagtgagggc agttgtcagg gtttttccat ttgttccagt
     4441 gacaacgaca atctcgtagt tcttagctag gttttgtaaa atatctttat caaattgaag
     4501 ggcgactttc cctgggagcg tacttccacg tccaagacgg cttaaaacga agtgggaaga
     4561 acgcccagca agaaggccca aagtagtttt taagttcatg tttctattat atcacaaaag
     4621 tatatcacaa aagagggaaa agacagattt ggtgtttcgt agaagtaaaa acagcccaaa
     4681 gagggctgtc agttaagatg agatttcaac ttaaatcgca aacaagtcat tcaagttctc
     4741 agccaaggtt gggtgagtga agatttgttt tgtgaagtaa gtgtaaggaa tcttgttgtc
     4801 catagcaaca gtaataatgt tgatgatttc ttgagaacct tctgagaaga tgcttgcacc
     4861 aagaatttct tttgtttcag tattaacaac agctttgaaa gctccgcgaa ggtctccatt
     4921 tacgtgacca cgaggcatgg ctgcaacagg gatttctttc actgcgtatg gaagtttcaa
     4981 atcagctgct tggctttcag tcaaaccaac ttgtgaaagt gcaggtgtga tgaacatagt
     5041 atttggcaca ttgagacggt cctcaagtgt gtagctgcca tctccagcaa ggtagctgta
     5101 aacaacacgg aagtcatcaa gtgaaatgta agtaaattga agaccaccgt tgacatctcc
     5161 aactgcaaag acaccaggaa cgtttgtttg acagtgttta tctactttaa tagcgccacg
     5221 ttcagttagt tcaatatctg tattttcaag ttgaagtggt tctacatttg gtttgcgtcc
     5281 agttgcgtag agaagggcgt cgaaacggta agtttcgtct tcagttacga caagcacttg
     5341 gtcaccgtcg tttttaattt cagtagtatg gatattttga agcaattcaa taccgtcttc
     5401 ttccatgtat tgtttagcaa gagctgcgat ggaaggttct gcacgaggta ggaatgtatc
     5461 caaggcatct aggactgtaa ccttgcttcc tagtttattg taaaggccag caaattcaag
     5521 accgatattt ccgccaccaa ggactccaag tttttcaggc aatttatcca agctttggat
     5581 acctgttgag tcaaagacgt ttttgcttgt agcaagtcca gggattggca agacgtttga
     5641 aacagcacca gtgttgatga cgatagtttc agcagtcaat tcttgttttt catcaccagc
     5701 ttggatttcg atgactttat ttgaaaggaa gtgagcttca gcatcaaaga tatcgacgcc
     5761 agtaccagca acagtcgtat agtttttacc gttgaggcga ccagtgatcg tgtttttggt
     5821 agcaatgact tcttcaaaag acaagtcttt ctcagcagca accagcaaag ttttagttgg
     5881 gatacaaccg atgttgatac aagttccacc gtacatagct ttgctacgtt caacgagggc
     5941 aacttttttg ccagctgaag ccaatttacc agctagtgtt ttaccagctt taccaaatcc
     6001 gataacgatt aaatcataag ttaacattta gaattcctcc tattcgaatt acattctagc
     6061 acaagaaaaa aacttttgca caattctgct acgaaaaaga cagaaaaata tgaaaacgct
     6121 tttcaggcaa aaaactagta attttttgac aagcttgata aactaaaatc ctatctattt
     6181 ttatataaga tagaataaat gttcgaaaat aggaggtttt atgaaatcga atcgttatat
     6241 tattgccttt gctggggtca ttttacactt aatgctgggt tcgacttatg cctggagtgt
     6301 ttatcgtaac cctattattg aaaaaacggg atgggatcag gcttctgttg ccttcgcctt
     6361 tagtctagca atcttttgtt tgggcttatc ggctgcattt atggggcgtt tggtagaaaa
     6421 atttggtccg agagtcatgg ggagtctatc tgcttttcta tacgcaggtg gaaatatctt
     6481 aacaggattt gcaatagacc gtcaggaact gtggttgttg tatctagctt atggcatttt
     6541 aggtgggctt ggtttgggag caggctatat tacccctgtg tcaacgatta taaaatggtt
     6601 tcctgataaa cgtggtctcg caacaggttt agcgattatg gggtttggtt ttgcttcttt
     6661 attgactagt cccatagcgc aacatctcat cgcaggggta gggcttgtag aaacttttta
     6721 tattttaggt gcaagttact ttattatcat gctcctagct tcacaattca ttaagcgtcc
     6781 aaatgagcaa gagcttgcaa ttttatctgc ttcagggaaa gaaaaaacag actctctgac
     6841 gcaagggatg actgcaaatc aggctctaaa aagcaatcgg ttttatatgc tttggattat
     6901 tttctttatc aacatagctt gtggtttagg cttaatttca gcggcatcgc caatggcaca
     6961 ggagatggct ggcttgtcta caagtcatgc agcagtaatg gtgggtattt tggggatttt
     7021 caatggattt ggtcgcttgc tctgggcgag tttgtctgac tatatcggtc gccctctaac
     7081 ctttagtata ttactgcttg tcaatctttt cttttctctc tcactttggc tctttacaga
     7141 ttccgtttta tttgtagttg ctatgtctat tttgatgact tgctatggag ctggtttttc
     7201 tttgattcca gcttatctca gtgatatttt tggaaccaag gaattggccg ctctgcatgg
     7261 ttatatttta acagcttggg caatggctgg tttagcggga cctattttat tagcagagac
     7321 ttataaaatg gctcattcgt acacacaaac cttgttcgtt tttctcattt tatacagtat
     7381 cgccttggct ttgtcttatt atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct
     7441 tacatgattt tctgtagaaa tggggctatc ttttgctctg gtcttgtgtt atactagata
     7501 ggttgcaaag aaaacagtac ttttcttttg tggaaaagaa gcaacacgat tttatatcta
     7561 gttatatgaa aatacgtcat aaaaagaaaa gtataaacta agccctatag ggtggcttcg
     7621 caccaccttt agaaagaaga ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt
     7681 gctagcagaa attgaaaaag ctggttttgt agaagctagt cctatccaag aacaaactat
     7741 tcctttggcc cttgaaggca aggatgttat cggtcaagct cagactggta caggaaaaac
     7801 tgcagccttt ggcttgccta cccttgaaaa aatccgtaca gaagaagcga ctatccaagc
     7861 tttggtcatc gctccaactc gtgaactagc tgtccaaagt caagaagaac tcttccgctt
     7921 tggtcgtagt aagggagtca aagtccgttc agtatatggc ggatcaagca ttgaaaaaca
     7981 aattaaggct cttaaatctg gtgcccatat cgtggtggga actccaggtc gcctcttgga
     8041 cttgattaaa cgcaaggcct tgaaattaca agacattgaa acccttatcc ttgacgaagc
     8101 ggatgaaatg cttaacatgg gcttccttga agacatcgaa gccattattt cccgtgtacc
     8161 tgagaaccgt caaactttgc ttttctcagc aactatgcca gatgccatca aacgtatcgg
     8221 tgttcagttt atgaaagccc ctgaacatgt caagattgcg gctaaggaat tgacaacaga
     8281 attggttgac cagtactata tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg
     8341 tctcatggat gtggcacaac cagaactcgc tattgtattt ggtcgtacca aacgccgtgt
     8401 ggatgaattg actcgtggtt tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga
     8461 cctagaccaa aacaaacgtc ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt
     8521 tttggttgcg acagacgttg cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta
     8581 caactacgat attccacaag atcctgagag ttatgttcac cgtatcggtc gtacaggtcg
     8641 tgctggtaag tcaggtcaat ctattacttt tgttgctcca aacgaaatgg gttaccttca
     8701 aatcattgaa aacttgacta agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga
     8761 atccttccaa tcaaaaaaac aggtagctct caagaaaatc gaacgtgatt ttgcagatga
     8821 aaccattcgt gccaactttg agaaatttgg taaggatgct cgcaaattgg ctgctgagtt
     8881 tactccagaa gaattggcaa tgtatatctt gagtctgaca gtccaagacc cagatagcct
     8941 tccagaagtg gagattgcac gtgaaaaacc actaccgttt aaaccatcag gtaatggttt
     9001 cggtggtaaa gctaagggag gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga
     9061 tcgccgtggc aatggtcgcc gtgatgagtt caaaaaagga agtcgtggca acgatcgttt
     9121 tgataaggaa aaacgttacc gtaaggataa taaaaaacca cgcaatactt taagcgaaaa
     9181 gcaaacaggc tttgttattc gtaacaaggg cgataaataa gaaaaagcgg ttcaaaatga
     9241 atcgcttttt tatataagga gaccgaatgt gaaaagacaa ataaaattat tatattatct
     9301 tttataatgt tatgatacac aaaaataggc aacttgtcaa tagaaaagga acaatttaat
     9361 taaaaatatt ctggttttta attaaattgt aagtcaatgc aagtcaataa ggaattttca
     9421 gataattatt gaaaaagaga cgtttttatg ttataatgat agcgattaaa ttcgaggtga
     9481 aaaatggcac atttattaga aaaaactaga aaaattacat caattttgaa acgctcagag
     9541 gagcagttgc aggatgagct tccttacaac gctattacgc gtcagttagc ggatattatt
     9601 cattgcaatg cctgcattat caatagtaag ggacgtctgc ttggctattt tatgcgttat
     9661 aaaacaaata cagatcgcgt agagcaattc ttccaaacta agattttccc agatgactac
     9721 gttcaagggg ctaatatgat ttacgaaaca gaagcaaact tgcctgttga gcatgatatg
     9781 agtattttcc ctgttgagag tagagatgat tttccagatg gcttgacgac tattgcaccg
     9841 attcatgtat cggggattcg ccttggttct ttgattattt ggcgtaatga taaaaaattc
     9901 gaagatgagg acttggttct tgttgagatt gccagtaccg ttgttgggat tcagcttctt
     9961 aacttccaac gtgaagaaga tgagaaaaat attcgtcgtc gtactgctgt caccatggcg
    10021 gtcaataccc tttcttactc cgaactccgt gctgtttcag caattttagg ggaattaaat
    10081 ggaaatgaag ggaagttgac tgcgtcagtg attgcagatc gtatcggaat cactcgctct
    10141 gtgattgtca atgctcttcg taaacttgag tctgcgggga ttattgaaag tcgctcactt
    10201 ggaatgaagg gaacctatct taaggtcttg atttcagata tttttgaaga agtgaagaaa
    10261 agagattact aatgacaaag gctttaattt cgattgatta tacagaagat tttgttgctg
    10321 atagtgggaa actaacagca ggtgctccag ctcaggcgat ttcggatgcc atcagcaagg
    10381 taactcgatt agcttttgaa cgaggagatt atatcttctt tactattgat gctcatgaag
    10441 aaaacgattg tttccatccg gaaagtaagt tattttctcc tcataatctg attgggacga
    10501 gtggacggaa tttatatgga gatttgggga tcttttatca agagcatggt tcagacagtc
    10561 gtgtcttttg gatggataaa cgccattact cagctttttc agggactgac ctagatattc
    10621 gtttgagaga gcgtagagtg tctaccgtta tcttaacagg tgtcttgacg gatatctgtg
    10681 tcctacatac agctatagat gcctataatc taggatatga catcgagatt gttaaaccag
    10741 ctgttgcttc catctggcct gaaaatcatc aatttgccct aggtcatttc aaaaatacac
    10801 tcggagctaa gttagtagat gaaaatctaa atgaactttc tgagtaacct ggttggtgaa
    10861 aatgaaaaaa tttgaaaaaa agtgttgaca agcatcccaa aagttgatat actagtaaag
    10921 taatcgatgc ggggatggcg gaattggcag acgcgcagga ctaaggatcc tgtgaccgct
    10981 ttaggtcgtg agggttcaag tccctctctc cgcataggaa aagagttagc taaagctagc
    11041 tcttttgtat ttctctaaaa aattagaatc cagtcaaatg tagtggagaa tcagcgaaaa
    11101 tatgggaaaa ctgatccttg tttctgcttt tgtcatagaa gaataataaa gattatcttc
    11161 ttcaaattct ccgatattct ctaaagtttt gtgcaagttg cacagaactt ttttattttt
    11221 ttggtcatct tgccatagaa atataaagcg ttttcatcta taatataatt atcaaaagac
    11281 aaaaggagtt cacctcatgg tagaattgaa tcttaaaaat atttacaaaa aatatccaaa
    11341 cagcgaacac tattcagttg aagatttcaa cttgaacatc aaagataaag aatttatcgt
    11401 tttcgtagga ccttcaggat gtggtaaatc aactacactc cgtatgattg ctggtcttga
    11461 agacattaca gaaggtactg catctatcga tggcgtggtt gtcaacgacg tagctccaaa
    11521 agaccgtgat atcgccatgg tattccaaaa ctacgctctt tacccacaca tgactgttta
    11581 tgacaacatg gctttcggtt tgaaattgcg taaatacagc aaagaagaca ttaacaaacg
    11641 tgttcaagaa gcagctgaaa tacttggatt gaaagaattc ttggaacgta aaccagctga
    11701 cctttcaggt ggtcaacgtc aacgtgttgc catggggcgt gcgattgtcc gtgatgcgaa
    11761 agtattcttg atggacgaac ctttgtcaaa cttggatgcc aaacttcgtg tatcaatgcg
    11821 tgctgaaatc gctaaaattc accgtcgtat cggagctaca actatctatg taactcacga
    11881 ccaaacagaa gcgatgacac ttgcagaccg tatcgttatt atgtcagcta ctaagaaccc
    11941 tgctggtaca ggtactatcg gacgtgtaga acaaatcggt actcctcaag aagtttacaa
    12001 aaatccagtt aacaaattcg ttgcaggatt catcggaagc ccagctatga acttcatcac
    12061 cgtgaaattg gttggtagcg aaattgtttc tgacggtttc cgtttgaaag tgccagaagg
    12121 agcattgaaa gttcttcgtg aaaaaggcta cgaaggaaaa gaattgatct ttggtatccg
    12181 tccagaagac gtgaatgcag aacctgcttt ccttgaaaca ttcccagact gtgttgtaaa
    12241 agcgactatc tctgtatcag aactgcttgg ttcagaatct cacctttact gccaagttgg
    12301 taaagacgag tttgttgcaa aagttgatgc tcgtgactac ttgcaaacag gtgcaacagt
    12361 tgagcttgga tttgacttga acaaagcaca cttcttcgat gtagaaactg aaaaaacaat
    12421 ctactaaaat aaataaaatt caaagcacta caagaaaaga tatctcttta tcaattgtag
    12481 tggagagata tcagttaatc tagggagaga aacaaaatgc ttctctcctt tttgctaggg
    12541 aagtcatatt atgcatctat attgtgatgc tctttaatac tcttcgaaaa tctcttcaaa
    12601 ccacgtcaac gtcgccttgc cgtacgtatg attactgatt tcgtcagttt tatctgcaac
    12661 ctcaaagatg tactttgagc agcttacggc tagtttccta gtttgctctt tgatttccat
    12721 tgagtattat ttgtgggtac catctacaag tgaagctata tgcgtaaact acgtgagcaa
    12781 ttgaattcga actagagagg taataataaa tttatgctat agttatggtg acttgtatgc
    12841 ttttgattct agtttatcaa ataatagatt agaattgtca gataatatca ttttgtgtta
    12901 taatgaagaa aaaacagagg tgttcaaatg tcagaagcag gtcataagtt tttagcaaaa
    12961 ttggggaaaa aacgcttacg tccaggtgga aagcgtgcca cagattggtt aattgcagaa
    13021 ggaggatttt caaaagaaaa gagaatacta gaggttgcgt gtaatagggg aactacagca
    13081 attgagttgg cacagcgttt tggttgcaag ataactgctg ttgatatgga tgctcaagct
    13141 ttagaagtgg ctaaaaaatc tgctggaacg gcaggtgttg ctcatttaat cagttttgaa
    13201 agagcaaatg caatgaaact tccttatcaa gatgctagtt ttgatattgt tataaatgaa
    13261 gctatgctga ctatgcaagc cgatcaagct aagaaaaaat gtgtaatgga atatctaagg
    13321 gtattaaaac ctggaggtct tctcttgaca catgatgtgc ttcttaagga agctaaagag
    13381 tctatcagac aggaattatc acaagcaatt catgtaaatg taggtccttt aactcaagat
    13441 ggttgggaac aggtgatgat agaatcaggt tattgtgatg tgaaagcatt gactggtgaa
    13501 atgacattaa tgaaattatc gggtatgatt tatgacgaag gtttgctagg aactttgaaa
    13561 atttgtgtaa atgcttgtaa aaaggagaat agaaagcagt ttttaactat gtataaaatg
    13621 tttgctaaga ataaacagaa attgggcttt attgcgatgg ctagttataa atcgtcaaaa
    13681 cgttagataa ttattgaagt taacttttcc ttttttcttt cttaaaaaat atgctataat
    13741 agagagtaaa aaactttgaa agaaagaaaa agatgaattt aaaagattac attgcaacaa
    13801 ttgaaaatta tccaaaggaa ggcattacct tccgtgatat tagtcctttg atggctgatg
    13861 gaaatgctta tagctacgct gttcgtgaaa tcgttcagta tgctactgac aagaaagtcg
    13921 acatgatcgt gggacctgaa gctcgtggat ttatcgtggg ttgtccagtt gcctttgagt
    13981 tgggaattgg ttttgcgcct gttcgtaagc caggtaaatt gccacgcgaa gttatttctg
    14041 ctgactatga aaaagagtac ggtgtcgata ccttgactat gcacgcggat gccattaagc
    14101 caggtcaacg tgttcttatt gtagatgacc ttttggcgac aggtggaact gttaaggcaa
    14161 ctatcgagat gattgaaaaa cttggtggtg ttatggcagg ttgtgccttc cttgttgaat
    14221 tggatgaatt gaacggccgt gaaaaaattg gtgactacga ctacaaagtt cttatgcatt
    14281 attaatgaaa acagtcccta gggctgtttt ctctacacta ggatataaaa atagactata
    14341 actagttaga gaaaaactat aattgaaaac tatatcttct tgcagtataa taaaaggact
    14401 aagtgtttga gatttgtctt caaacatatg caattattcc tgaaagagta cagttaggag
    14461 agggttatgc cgattcgaat tgataaaaaa ttgccagctg ttgagatttt acggacagag
    14521 aatatctttg tcatggatga tcaacgtgct gcccaccaag atatccgtcc tttgaagatt
    14581 ttaattttaa atctcatgcc acagaaaatg gtcacagaga cccagttgtt gcgccacttg
    14641 gctaatacac ccctacaact ggatattgat tttctctata tggagagcca ccgttctaaa
    14701 acaactcgtt cagagcacat ggagaccttc tataaaactt ttcctgaagt caaggatgag
    14761 tattttgatg ggatgatcat cacgggtgct ccagttgagc atttaccatt tgaggaagtg
    14821 gactattggg aggaatttag acagatgctt gagtggtcta agactcatgt ctattcgacc
    14881 cttcatatct gttggggggc tcaggctggg ctttatctgc gctatggtgt agaaaaatac
    14941 cagatggaca gtaagctatc aggtatttat cctcaggaca ccctaaaaga gggtcacctt
    15001 ctatttagag gctttgatga tagctatgta tcccctcatt cacggcacac ggagatttct
    15061 aaggaagagg tcttaaacaa gaccaatctc gagattttat cagaaggacc tcaggttggg
    15121 gtttctattt tggccagtcg tgatttacga gaaatttata gttttggtca tttggagtat
    15181 gaccgtgata ccttggcaaa agagtatttt cgagatcgtg atgcaggttt cgacccacat
    15241 attccagaaa attactttaa agatgatgat gttaatcagg taccttgtct ttgttggtct
    15301 tcatctgcag ccctcttttt cagtaattgg gtaaaccatg cggtctatca ggagacgcct
    15361 tttgattgga gaaagataga agatgatgca tctgcatatg ggtatttata agaggaatta
    15421 tgacatattt agacgctttt aaatcaggta ccttggtttt accgagtgcc ctgctcttgc
    15481 attttaagga actctttcct tctagcgacg attttctggt ttggcaattt ttctatttgc
    15541 aaaatacgac aggcttagaa gaaatgtcgc caagccagat tgctgaaagg attggcaagg
    15601 aaatttcgga tgtcaaccag tccatttcta atctgacgga aaggggactg ctccagtatc
    15661 gtactatcga attaaatggc gaaattgaat tgctctttga tgctagtttg gccttggaac
    15721 gtttggatga cctgtttgga gcagttcgtt caagttcaga ccagctaaca cctcaaaacc
    15781 agctcaagga tttggtggaa accttccagc aggagttggg acgattgttg acgccttttg
    15841 agattgagga tttgatcaag acactaaagg aagatggaac cagtgctgac ttgattaagg
    15901 aggctcttcg tgaagctgtt ttgaatggaa aaccaaactg gaagtacatt caggcgattt
    15961 tgagaaactg gcgccatgaa ggaatcaaga gtgtggctca aattgaggcc aagagagcag
    16021 aaagagaagc aagcaatcct cagttgacac aggtatctgc agatttcaga aatgccatgg
    16081 atctctggaa ggattaatcc atgcaagtag gcttgaaatc cgagtaagat ttgcaagctg
    16141 tgtataattg tgatagaata aatagaaaat aaattgaaaa aagaggtatg tgaaatgtca
    16201 cgtaaaccat ttatcgctgg taactggaaa atgaacaaaa atccagaaga agctaaagca
    16261 ttcgttgaag cagttgcatc aaaacttcct tcatcagatc ttgttgaagc aggtatcgct
    16321 gctccagctc ttgatttgac aactgttctt gctgttgcaa aaggctcaaa ccttaaagtt
    16381 gctgctcaaa actgctactt tgaaaatgca ggtgctttca ctggtgaaac tagcccacaa
    16441 gttttgaaag aaatcggtac tgactacgtt gttatcggtc actcagaacg ccgtgactac
    16501 ttccatgaaa ctgatgaaga tatcaacaaa aaagcaaaag caatctttgc gaacggtatg
    16561 cttccaatca tctgttgtgg tgaatcactt gaaacttacg aagctggtaa agctgctgaa
    16621 ttcgtaggtg ctcaagtatc tgctgcattg gctggattga ctgctgaaca agttgctgcc
    16681 tcagttatcg cttatgagcc aatctgggct atcggtactg gtaaatcagc ttcacaagat
    16741 gatgcacaaa aaatgtgtaa agttgttcgt gacgttgtag ctgctgactt tggtcaagaa
    16801 gtcgcagaca aagttcgtgt tcaatacggt ggttctgtta aacctgaaaa tgttgcttca
    16861 tacatggctt gcccagacgt tgacggtgcc cttgtaggtg gtgcgtcact tgaagctgaa
    16921 agcttcttgg ctttgcttga ctttgtaaaa taatcagtaa gtagcaaaag ctaggtggaa
    16981 cagcattcag atgtctgtta cattttttat aggagaggaa agattgaaaa taaaaattgg
    17041 attagcaagt atctgtttac taggcttggc aactagtcat gtcgctgcaa atgaaactga
    17101 agtagcaaaa acttcgcagg atacaacgac agcttcaagt agttcagagc aaaatcagtc
    17161 ttctaataaa acgcaaacga gcgcagaagt acagactaat gctgctgccc actgggatgg
    17221 ggattattat gtaaaggatg atggttctaa agctcaaagt gaatggattt ttgacaacta
    17281 ctataaggct tggttttata ttaattcaga tggtcgttac tcgcagaatg aatggcatgg
    17341 aaattactac ctgaaatcag gtggatatat ggcccaaaac gagtggatct atgacagtaa
    17401 ttacaagagt tggttttatc tcaagtcaga tggggcttat gctcatcaag aatggcaatt
    17461 gattggaaat aagtggtact acttcaagaa gtggggttac atggctaaaa gccaatggca
    17521 aggaagttat ttcttgaatg gtcaaggagc tatgatacaa aatgaatggc tctatgatcc
    17581 agcctattct gcttattttt atctaaaatc cgatggaact tatgctaacc aagagtggca
    17641 aaaagtgggc ggcaaatggt actatttcaa gaagtggggc tatatggctc ggaatgagtg
    17701 gcaaggcaac tactatttga ctggaagtgg tgccatggcg actgacgaag tgattatgga
    17761 tggtgctcgc tatatctttg cggcctctgg tgagctcaaa gaaaagaaag atttgaatgt
    17821 cggctgggtt cacagagatg gtaaacgcta tttctttaat aatagagaag aacaagtggg
    17881 aaccgaacat gctaagaaaa tcattgatat tagtgagcac aatggtcgta tcaatgattg
    17941 gaaaaaggtt attgatgaga acgaggtgga tggtgtcatt gttcgtctag gttatagcgg
    18001 taaagaagac aaggaattgg cgcataacat taaggagtta aaccgtctgg gaattcctta
    18061 tggtgtctat ctctatacct atgctgaaaa tgagaccgat gctgagaatg acgctaaaca
    18121 gaccattgaa cttataaaga aatacaatat gaacctgtct taccctatct attatgatgt
    18181 tgagaactgg gaatatgtaa ataagagcaa gagagctcca agtgatacag acacttgggt
    18241 taaaatcatc aacaagtaca tggacacgat gaagcaggcg ggttatcaaa atgtatatgt
    18301 ctatagctat cgtagtttat tacagacgcg tttaaaacac ccagatattt taaaacatgt
    18361 aaactgggta gcggcctata cgaatgcttt agaatgggaa aacccttatt attcaggaga
    18421 aaaaggttgg caatatacct cttctgaata catgaaagga atccaagggc gcgtagatgt
    18481 cagcgtttgg tattaagcga tgattt
//
LOCUS       DAVLHM010000042        18253 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLHM010000042 DAVLHM010000000
VERSION     DAVLHM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18253
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.042"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(141..1076)
                     /locus_tag="VXE45_001653"
     CDS             complement(141..1076)
                     /locus_tag="VXE45_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0789659.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1073..1933)
                     /locus_tag="VXE45_001654"
     CDS             complement(1073..1933)
                     /locus_tag="VXE45_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0789660.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2041..4203
                     /locus_tag="VXE45_001655"
     CDS             2041..4203
                     /locus_tag="VXE45_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0789661.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4295..5554
                     /locus_tag="VXE45_001656"
     CDS             4295..5554
                     /locus_tag="VXE45_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0789662.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5568..6434
                     /locus_tag="VXE45_001657"
     CDS             5568..6434
                     /locus_tag="VXE45_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0789663.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTRWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6448..7281
                     /locus_tag="VXE45_001658"
     CDS             6448..7281
                     /locus_tag="VXE45_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0789664.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKLTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7282..7362
                     /locus_tag="VXE45_001659"
                     /pseudo
     CDS             7282..7362
                     /locus_tag="VXE45_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7639..9081
                     /gene="gtfA"
                     /locus_tag="VXE45_001660"
     CDS             7639..9081
                     /gene="gtfA"
                     /locus_tag="VXE45_001660"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0789665.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTIEIETPTVHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9219..10412
                     /locus_tag="VXE45_001661"
     CDS             9219..10412
                     /locus_tag="VXE45_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0789666.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11099..13078
                     /locus_tag="VXE45_001662"
     CDS             11099..13078
                     /locus_tag="VXE45_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0789667.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSGVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13145..14641
                     /locus_tag="VXE45_001663"
     CDS             13145..14641
                     /locus_tag="VXE45_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789668.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14641..15567
                     /locus_tag="VXE45_001664"
     CDS             14641..15567
                     /locus_tag="VXE45_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789669.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15576..16643
                     /locus_tag="VXE45_001665"
     CDS             15576..16643
                     /locus_tag="VXE45_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789670.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16654..17580
                     /locus_tag="VXE45_001666"
     CDS             16654..17580
                     /locus_tag="VXE45_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789671.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17655..>18253)
                     /locus_tag="VXE45_001667"
     CDS             complement(17655..>18253)
                     /locus_tag="VXE45_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0789672.1"
                     /translation="TVSLPNAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEHKA
                     IKHYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFH
                     FQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLI
                     KLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5377 a         3236 c         3838 g         5802 t
ORIGIN      
        1 aaaaataggc tccataatat ctatagggga tttacccact acaaatatta tagagacaat
       61 aaaacttcag atccgtaaaa cttaattgaa ttactaatct gaagttattt ttatatcgtt
      121 tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc actatttagc
      181 cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga gatgtcttta
      241 gcaagtccct tgtagtcttt ttgctctagt gtgaaagtga cttcttttcc tagaatgaat
      301 gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa agcacgccag
      361 atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa gctggcagct
      421 ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac tccaataatg
      481 atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat tcctccaatt
      541 ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat taaagttagg
      601 ttcttaatgg ctttgtagac agctccagct acaagtagtg tgtaggatgg taatttgtca
      661 taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg tgagtagaag
      721 gaacgttgaa aacggcctcg gcctgctgtt tgataggaag ctagatagag ggtatttgct
      781 tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt ttcgggttta
      841 aagctgactt taattggaag attttcttct agaatctctg gaagaataag gtcaccattc
      901 atcagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg ttctagtcgc
      961 ttgatggctt tccaaattgc tgttcggctt agggatagtt tttctgcgat tttttctccg
     1021 ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga tttcataatg
     1081 ttgcctttct tactagttgg tattgagagt attcttttct tgtatgactt ggagtctgat
     1141 taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct accgagtatg
     1201 caattacctt gatggactct tgggtatttt cgagaagttg tctagctcgg tgcattcgaa
     1261 cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg cttgataagt
     1321 agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat tgaggatagt
     1381 ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa atattctttt
     1441 ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt tgtcccatga
     1501 tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca atgtctgaga
     1561 tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag gattgatcag
     1621 aaatttggga aagagcaaaa taatcagggg ctttccctcc agtgattcct aaccagtagt
     1681 aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt tttaatagaa
     1741 agaaatctcc ttcttttaaa tcaacaattt tacccttgta atgaaatttt ccttgtcctt
     1801 tagtaatgta atgtaggacg tatgtatcac gaatggctgg accaaaagag taattaggtg
     1861 tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc tggtattctg
     1921 aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga gacatttttc
     1981 tattttggaa agcgatttca ggtgataaaa tagagtcaat aaagtgatga ggtgaagtaa
     2041 atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct aagtttgatt
     2101 attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat taagaactat
     2161 aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc aacagctact
     2221 aatcgaacct ttagtttaga tactcaacgt caaatttttg gacaacatgg cttaggagat
     2281 tttaggaaac caaccataca ggttcagcat aatgtaactg aagtaacaga ctttcgattt
     2341 gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc tccacatagc
     2401 atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca acttagtctg
     2461 actttgtatt atactacttt taataatgat gcgactattg ctagctacag taaattagat
     2521 aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc tgattttcca
     2581 gctgcagatt acgaaatagt aactctgcag ggtgcttatg ctcgtgaaaa gactgttaga
     2641 cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc ttctggtcat
     2701 gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc tgggaatgtg
     2761 tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa aaatcaattg
     2821 aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa gttagcccct
     2881 gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg attaactggt
     2941 attagtcatg aaagtcagaa ttttgtactg aagcacatta tgctaagtga attttctaaa
     3001 aaagaacgtc caattctaat caataactgg gaagctactt actttgactt tcagagagaa
     3061 aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt tgtattagat
     3121 gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg ggttgttaat
     3181 gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga aagaggtttg
     3241 cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt gtatcgtcaa
     3301 catcctgact gggctattca ggttcctggc tatgagcata cttattctcg gaatcaatta
     3361 gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt agatcaactc
     3421 ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat cactaagcta
     3481 gggaatggat taacttatct agagacacag atgcaatctc atcagtacat gctggggctt
     3541 tatgaactcg tttcttatct gacagagaag cacagccata ttctctttga gtcctgctct
     3601 ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt ctgggctagt
     3661 gataatactg atgccattgc acgtttacca attcaatacg gttcatccta tttctatcca
     3721 accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg acgaatgaca
     3781 ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga gcttgatttg
     3841 acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt gtataaagaa
     3901 ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga tactgcatcc
     3961 aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta cgttcgcgtt
     4021 ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga tgaagaggga
     4081 ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat gtatgcgggc
     4141 ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt tagaaaacta
     4201 tgatatgtac tgaccccaaa agttagattt attctgtcta acttttgggg tgcagttcaa
     4261 taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa aaatcggact
     4321 tcttgcaact acaggtttag ctttgtttgg gctcggcgct tgctccaact atggtaaatc
     4381 tgcggatggc acagtgacca tcgagtattt caaccagaaa aaagaaatga ccaaaacctt
     4441 ggaagaaatc actcgtgatt ttgagaagga aaaccctaag atcaaggtca aagtcgtcaa
     4501 tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg tgcctgatgt
     4561 ggtcaatatt tacccacagt ccattgaact gcaagaatgg gcaaaagcag gtgtttttga
     4621 agatttgagc aacaaagact acctgaaacg cgtgaaaaat ggctacgctg aaaaatatgc
     4681 tgtaaacgaa aaagtttaca acgttccttt tacagctaat gcttatggaa tttactacaa
     4741 caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg aatttgaaca
     4801 gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag gtgcagatgc
     4861 ttggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg gaggaaaaga
     4921 agcaaatcaa taccttcgtt attctcaacc aaatgccatt aaattgtcgg atccgattat
     4981 gaaagatgat atcaaggtca tggacatcct tcgcatcaat ggctctaagc aaaagaactg
     5041 ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg tcctcatgac
     5101 accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact ttaagattgg
     5161 gaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg cgggagactt
     5221 ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct ttgtggaata
     5281 tatgacccgt ccagaagtca tgcaaaaata ctacgatgtg gacggatctc caacagcgat
     5341 cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg aatatgcctt
     5401 tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag acttccatac
     5461 cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg atttgaatgc
     5521 cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg aaaaaagtat
     5581 tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa gcaattttct
     5641 tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca ggattgactt
     5701 acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat ccaaaattca
     5761 tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt gagattgcac
     5821 tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc ttcttccgtg
     5881 cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc ttcaagcaag
     5941 tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt ctccaaacca
     6001 gtcttttagg gactaggtgg ggagcaatct ttgcggctgt ctttgtcctt ctttggcaag
     6061 gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca actgagatta
     6121 cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac attgaattgc
     6181 cttacttgct accaagtgtc tctatagtct ttatcctagc cctaaaaggt gggctgactg
     6241 cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca acctcacttg
     6301 ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc aatgccattg
     6361 ccgtaatctt gttcttctta attgtagtga tttcgatcat ccaattgaga gtatctaaga
     6421 aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc cctgattggc
     6481 aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct tgctaccctc
     6541 tttagttcct tcaaactcac taaggatatt gtagataatt tctttggctt tccaaccaac
     6601 ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta ttattggaac
     6661 tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc tatggcagcc
     6721 tactccatcg ctcgcaatat gagtaaaaga aaagccttta ccatcatgta taccctctta
     6781 atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt tatgatgagt
     6841 aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta tgcgattcca
     6901 cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag tctggatgaa
     6961 gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat cttcccaatg
     7021 atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg gaatgacttc
     7081 atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc tttgttccaa
     7141 tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc ttacgtggtc
     7201 ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat ttcaggaatg
     7261 agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag gaagctagcc
     7321 gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt cagtaaccat
     7381 acctacggta aggtgaagct gacgtggttt gaagagattt tcgaatagta taagaagagc
     7441 tcatggaatc tatagtcttt gacacagagg aagagttcag cttgttgata attctatgta
     7501 gaaaacaaga aagtagtact ttgtttatca cagtctatat tagtacgagt ttgatgataa
     7561 atagagattt aaaatgaatt ttatttatga agccagatca tatgagactt ggcttcaatt
     7621 agaaaaagga gagtaatgat gccaattcaa aataaaacca tgttgattac ctattctgat
     7681 agccttggaa ataatcttaa agacttatat gataatttgg aagagcattt tggagatgct
     7741 attggaggag ttcacctttt accatttttc ccatcaacag gtgatcgtgg atttgcgcca
     7801 gttgactacg acgaagtgga ctcagctttt ggtgattggg aggatgttaa gcgtttaggt
     7861 gagagatatt atcttatgtt tgattttatg attaatcata tttctcgtca atccaagtat
     7921 tataaggact atcaagaaaa acatgaagcc agtgaattta aagatctctt tttaaactgg
     7981 gataagtttt ggccagaaaa ccgtccgaca cagtctgatg tagatttaat ttacaagcgt
     8041 aaggatcgtg caccaaagca agagattgtg tttgaagatg gttcagtgga acatttgtgg
     8101 aatacctttg gtgaggagca gattgatctt gatgtgacca aagaagtaac tatggaattt
     8161 atccgtaaga ccattcagca cttggcaagt aatgggtgtg atttgattcg tctagatgcc
     8221 tttgcttatg cagtgaagaa attggatact aatgatttct ttgtggaacc agatatttgg
     8281 gatttattgg acaaagttcg agatatcgct gctgagtatg ggacagagct tttacctgag
     8341 attcatgaac actattcgat tcagtttaaa atagcagacc atgattacta tgtttatgat
     8401 tttgctcttc caatggtgac actttatact ctttacagtt ccagaacaga gcgtttggct
     8461 aagtggttaa agatgagccc gatgaagcaa tttacgacgc tagataccca tgatgggatt
     8521 ggagtagtag atgtcaagga tatcctgacc gatgaggaga ttgactatgc ttcaaatgaa
     8581 ctctataagg ttggagccaa tgtcaaacgt aagtactcta gtgccgagta taacaactta
     8641 gatatctacc aaatcaattc aacctactat tcagcgcttg gagatgatga tgtcaagtat
     8701 tttctcgctc gtctaattca agcttttgcc ccaggtattc ctcaggttta ctatgtgggt
     8761 ctattagcag gcaagaatga cttgaaatta ttagaagaaa ctaaagaagg tcgaaatatt
     8821 aatcgtcatt actatagcaa cgaggaaata gcaaaagaag tgcaacgatc tgttgtgaag
     8881 gcccttctca atctattttc tttccgtaac cgttcagaag cctttgatct agaagggact
     8941 attgagatag agacaccaac agttcacagc attgtaatca aacgtcaaaa taaagataag
     9001 tccgtaacag cagtagcaga aattgatttg caaaatcaga cttatcgggt aattgagaat
     9061 ggagttgaag taacattttg aagccttgat atggtggata aaatagggtt tttattttgg
     9121 aaaacgtttc ctttgttttc aaattgctaa aaaagtggta caatatagga tagcttacta
     9181 ttatctgaat cagctgattt ggagagaaag gattcatttt gaaatcaata ggctttattg
     9241 aaaagctgaa ggggttgtct agtaaagagc tgattttatt gggaattatc ctaagtatct
     9301 ttttaccctt ttatcttttt gtagttgtac tctgtttata tattatcagt ttgattttta
     9361 caggagacat gaaaagtatt cttcagaaaa tgggggagca tccgatgctg cttctttttc
     9421 ttagctatag tactgttata tccattcttg cacaaaattg gatgggtctt gtggcttcag
     9481 taggaatgtt tctatttact attttctttt tgcactatca gtcgatttta tcccataaat
     9541 tctttcgatt gattttgcag ttcgtcttgt ttggtagtgt cttgtcagct gcttttgcca
     9601 gtttagaaca tttccaaatt gtgaagaaat ttaactatgc ttttctttca cccaatatgc
     9661 aggtgtggca tcagaaccgg gcagaagtga ctttctttaa tcctaattat tatggaatta
     9721 tttgttgttt ctgtattatg attgctttct atctgtttac aacgaccaag ttgaattggt
     9781 tgaaagtatt ctgtgtgatt gcaggctttg ttaatctctt tggtttgaac tttactcaaa
     9841 atcgaactgc ctttcctgct attatcgctg gagcaattat ctatctcttt acgactatta
     9901 aaaactggaa ggccttttgg cttagtattg gggtcttcgc gattggtttg agtttcctct
     9961 tttctagtga tttgggagtt cgaatgggta ctttagactc ttctatggaa gaacgcattt
    10021 ctatctggga tgctgggatg gccttgttta agcaaaatcc tttttggggt gaagggccat
    10081 tgacctatat gcactcttat cctcggatac atgctcctta tcatgaacat gcccacagtc
    10141 tttatattga tacgattctg agttacggaa ttgtgggtac cattttatta gttttgtctt
    10201 ctgttgctcc tgttcgcttg atgatggata tgagtcagga gtcggggaaa cgtccgatta
    10261 tcggccttta tctatctttc cttacagtgg ttgctgtgca cggaattttt gacttggctc
    10321 tcttctggat tcagtcaggc tttattttct tgctagttat gtgcagtatt ccattggagc
    10381 atcgaatgtt ggtatcggac atgacggatt aagttttata agtttgaaat cttctacctt
    10441 gggtaggaga tttttttata cgatgggcat gtcgtgcatc tgaggtgtaa gtcctctgta
    10501 gggatccact accggtgaat acaatagcgc tccccaagcc tgactatcgt gaggtagcgg
    10561 attaaaatgg tctggggata gatcgtttta agtctgacgc aggaaataag aattgtcaga
    10621 gaaagcaata gtgaaatcgt aggctatgaa tagaaacgtg atagcgagga gcatatagtg
    10681 gataaggtag cgagaaattt taaagtataa aagatagtct taatctatat atgtaaatca
    10741 caaaagtaat tgaattcgga ataaggttgg tgtgaaaaga catagtaaac tgaatcttga
    10801 atactagaat gatacttcta caatattgtt ataatttaat ttgaattcca aaatcacatt
    10861 gttccgtccg tatttcattt tactgtatgt cttcctaaac tccaaagttt ctgcgtcaaa
    10921 tttcctattt tcactgtagt ctttgacact tcgaacgaca atttgaatca tatattcaaa
    10981 aaaaaatgaa aaatttgtgc caacaagcct aaatattctg aaaatttgtt tgatttttaa
    11041 tggataatgt gatataatgg ttgtcaatct ataattcaca taaacagagg agtagaaaat
    11101 gaaaaaaaat cgtgtatttg ctacagcagg tcttgtttta ttagcagcag gtgtacttgc
    11161 agcatgcagt tcttcaaaat catctgattc atcagcccct aaagcttatg gctatgttta
    11221 tacagcagac ccagaaacct tggactacct gatttcaagt aaaaatagta caacagtagt
    11281 gacttcaaat gggattgatg gtttattcac taacgataat tacggtaatc ttgctcctgc
    11341 agttgcagag gattgggaag tctctaagga tggtttgacc tacacttata agattcgtaa
    11401 aggggttaaa tggtttacct ctgatggaga agaatatgca gaggtgacgg ctaaagattt
    11461 cgtgaacggt ttaaaacacg cagcagataa aaaatcagaa gctatgtatt tagctgaaaa
    11521 ttcggttaaa ggcttggcag attatctatc aggaacttca acagattttt caacagttgg
    11581 tgtcaaggcg gttgatgatt atacgttaca atacactttg aaccagcctg aaccgttctg
    11641 gaactctaag ttgacctatt ctattttctg gcctctgaat gaagaattcg aaacatcaaa
    11701 aggaagcgat tttgctaaac caacagatcc gacatccttg ctttataatg gtccattctt
    11761 gttgaaaggg ttgactgcaa aatcttctgt agagtttgta aaaaatgagc aatattggga
    11821 taaagaaaat gtccacctag atactatcaa tctagcttac tatgatggat cagatcagga
    11881 gtcgctagag cgtaacttca ctagtggagc ttatagttat gcccgtcttt accctaccag
    11941 ctccaactat tctaaggttg cagaagaata caaggacaat atctattaca cacaatcagg
    12001 ctctgggatt gctggtctgg gtgtgaatat tgatcgccaa agttacaact atacttctaa
    12061 aactacagat tcagagaaag tagctactaa gaaggcattg cttaacaaag atttccgtca
    12121 agccttgaat tttgctcttg atcgctcagc ttactcagct caaatcaatg gtaaagatgg
    12181 agcagcttta gcagttcgta atttatttgt aaaaccagac tttgtttcag ctggtgagaa
    12241 gacctttggt gatttagtcg ctgctcaact tcctgcttat ggtgatgagt ggaaaggtgt
    12301 gaatttagct gatgggcagg atggtttatt caatgctgac aaggccaagg cagagtttgc
    12361 gaaagctaag aaagctttag aagcagacgg cgttcagttt cctattcatc tggacgttcc
    12421 agtagaccaa gcatcaaaaa actacatatc tcgtattcag tcctttaaac aatctgtaga
    12481 aacagttctt ggtgttgaaa atgtcgttgt tgatattcaa caaatgacaa gtgatgaatt
    12541 ccttaatatt acttactatg ctgccaatgc ttcatctgag gattgggatg tatcaggagg
    12601 agtttcatgg gggccagact atcaagaccc atctacttac ctggatattt taaaaacaac
    12661 tagcagtgaa actacaaaaa catatttagg atttgataat ccaaatagcc cttcagtagt
    12721 tcaagttggt ttgaaagaat acgataaatt agttgatgaa gctgccaaag agacaagcga
    12781 cttgaatgtc cgttatgaaa aatatgcagc ggctcaagca tggttgacag atagttcact
    12841 ctttattcct gctatggctt cttctggtgc agcaccagtg ctttcacgaa ttgttccatt
    12901 tactggagct tctgcgcaaa caggctctaa ggggtcaggt gtttacttca aatatttgaa
    12961 attacaagat aaagtggtga ctaaggaaga gtatgaaaaa gctcgtgaaa aatggttgaa
    13021 agaaaaagct gaatcaaatg agaaagctca aaaagaattg gcaagtcatg tgaagtaaat
    13081 aatttctaat agaactttct ctccatgagg agaaggttct tttgggattt ttaaaggaaa
    13141 taatatgaaa aaatatattt ttatgcgtgt tttgcggtca ttggtttcga ttttcttagt
    13201 aacgactttg acctacacga ttatctatac cttggttcct cgaaaattga ttttcaagca
    13261 ggatcctaac tataataaaa ttgcgacaac ggctgataaa cgtgataact atgaaaatac
    13321 tgtgtttgag cgtatgggct acattgagta ttacgatact aaagagttgc aagaaaaggc
    13381 aagtagcatg gattcttctg taacagtaga agcaaatgcg accaataaag ctatttatga
    13441 aaagtacatc aatcaattag gtcatggttg gactttggga gaatttactg aaagtggtca
    13501 attctatgct actcgtgaaa ttccaatttt tgaacgtgtt tttcacttct atgctaactt
    13561 gattgacatt gaccatacaa ataaaatcca agaccctgaa aatccagact tgaaacgcta
    13621 ccttcgtttt gaaaatgatc cagctatcgg atggtcattg gtcggttcag gaactaaaca
    13681 taaatatctc ttgtacttta acagtcagtt cccatttgtt catcaaaact ttgtgaactt
    13741 gaatttaggt gactcttacc caacctatgc taatacacca gttcttcagg ttattactca
    13801 aggtcaagga caaaccaaaa ctgcccaagt tcagttccca acaggtaaga aaacgtcttc
    13861 tgtaaatatt tactcaagaa cctacaagtc acctagtcag gctgactctc gtgaagtagc
    13921 tagctatggg aaagatgatc cttatacagc gactgaaagt aattaccaat atccatctat
    13981 gattgtcagc tctgctatta ctggtttgat tggtttggtt cttgcctatg ctcttgccgt
    14041 gccacttggt tcagccatgg ctcgtttcaa gaacacttgg attgatagcc tctcaacagg
    14101 gactttgacc ttcttgcttg ctcttccaac gattgccttg gtttacatcg ttcgattgat
    14161 tggatcatct attgcccttc cagattcatt ccctatcttg ggagctggag attggcgttc
    14221 ttacgtttta ccagcagtca tccttggttt attgggtgct cctgttacag ccatttggat
    14281 tcgtcgttac atgattgact tgcaatctca agactttgtt cgtttcgctc gtgcaaaagg
    14341 tttgtctgaa aaagaaattt caaacaaaca catctttaaa aatgccatgg ttccgctggt
    14401 ttcaggaatt cctggtgcca ttattggggt tatcggtggt gcaaccctta ctgaaacagt
    14461 cttcgccttc ccaggtatgg gtaaaatgtt gattgactct gtaaaagcat ctaataactc
    14521 tatggtcgtt ggtcttgtct tcatctttac atgtatttct atcttctcac gtcttttggg
    14581 agatatttgg atgactatta ttgacccacg tattaaattg actgagaaag gaggcaaata
    14641 atgtctacaa tcgataaaga aaaatttcag tttgtaaaac gtgacgattt tgcctctgaa
    14701 actattgatg cgccagcata ttcttactgg aaatcagtgt ttaaacaatt tatgaagaaa
    14761 aaatcaactg tagtcatgtt gggaatcttg gtagccatca ttttgataag tttcatctac
    14821 ccaatgtttt ctaagtttga tttcaatgat gtcagcaagg taaacgactt tagtgttcgt
    14881 tatatcaagc caaatgcgga gcattggttc ggtactgaca gtaacggtaa atcgctcttt
    14941 gacggtgtct ggttcggagc tcgtaactcc atcctcattt ctgtgattgc gacagtgatt
    15001 aacttggtta tcggtgtttt tgtcggtggt atttggggta tttcaaaatc agttgaccgt
    15061 gtcatgatgg aagtttacaa cgtcatctca aacatcccac ctcttttgat tgttattgtc
    15121 ttgacttact caatcggagc tggattctgg aatctgattt ttgccatgag cgtaacaaca
    15181 tggattggta ttgccttcat gattcgtgtg caaatcttgc gctatcgtga cttggaatac
    15241 aacttggcgt cacgtacttt gggaacacca accttgaaga ttgttgccaa aaatatcatg
    15301 cctcaattgg tatctgttat tgtgacaacc atgactcaaa tgcttccaag ctttatctca
    15361 tacgaagcct tcttgtcttt cttcggtctt ggattaccga ttacagtgcc aagtttgggt
    15421 cgtttgattt cggattattc acaaaacgta acaaccaatg cttacttgtt ctggattcca
    15481 ttgacaaccc ttgtcttggt atccttgtcc cttttcgtag ttggtcaaaa cttagcggat
    15541 gctagtgatc cacgtacaca tagataggag tagaaatgac aaaagaaaaa aatgtaattt
    15601 tgactgctcg cgatattgtc gtggaatttg acgttcgtga caaagtattg acagccattc
    15661 gcggcgtttc ccttgaacta gtcgaaggag aagtattagc cttggtaggt gagtcaggat
    15721 caggtaaatc tgttttgaca aagaccttca caggtatgct cgaagaaaat ggtcgtattg
    15781 cccaaggtag tattgactac cgtggtcagg acttgacagc tttatcttct cacaaggatt
    15841 gggaacaaat tcgtggtgct aagattgcga ctatcttcca ggacccaatg actagtttgg
    15901 accccattaa aacaattggt agtcagatta cagaagttat tgtaaaacac caaggaaaaa
    15961 cagctaaaga agcgaaagaa ttggccattg actacatgaa taaggttggc attccagacg
    16021 cagatagacg ttttaatgaa tacccattcc aatattctgg aggaatgcgt caacgtatcg
    16081 ttattgcgat tgcccttgcc tgccgacctg atgtcttgat ctgtgatgag ccaacaactg
    16141 ccttggatgt aactattcaa gctcagatta ttgatttgct aaaatcttta caaaacgagt
    16201 atcatttcac aacaatcttt attacccacg accttggtgt ggtggcaagt attgcggata
    16261 aggtagcggt tatgtatgca ggagaaatcg ttgagtatgg aacggttgag gaagtcttct
    16321 atgaccctcg ccatccatat acatggagtc tcttgtctag cttgcctcag cttgctgatg
    16381 ataaagggga tctttactca atcccaggaa cacctccgtc actttatact gacctgaaag
    16441 gggatgcttt tgccttgcgt tctgactacg caatgcagat tgacttcgaa caaaaagctc
    16501 ctcaattctc agtatcagag acacattggg ctaaaacttg gcttcttcat gaggatgctc
    16561 caaaagtaga aaaaccagct gtgattgcaa atctccatga taagattcgt gaaaaaatgg
    16621 gatttgccca tctggctgac taggaggaag gaaatgtctg aaaaattagt agaaatcaaa
    16681 gatttagaaa tttccttcgg tgaaggaagt aagaagtttg tcgcggttaa aaatgctaac
    16741 ttctttatca acaagggaga aactttctcg cttgtaggtg agtccggtag tgggaaaaca
    16801 actattggtc gtgctatcat cggtctaaat gatacaagta atggagatat catttttgat
    16861 ggtcaaaaga ttaatggtaa gaaatcgcgt gaacaagctg cggaattgat tcgtcgaatc
    16921 cagatgattt tccaagaccc tgccgcaagt ttgaatgaac gtgcgactgt tgattatatt
    16981 atttctgaag gtctttacaa tcaccgttta tttaaggatg aagaagaacg taaagagaaa
    17041 gttcaaaata ttatccgtga agtaggtctt cttgctgagc acttgactcg ttaccctcat
    17101 gaattctcag gcggtcaacg tcaacgtatc ggtattgccc gtgccttggt catgcaacca
    17161 gactttgtta ttgcagatga gccaatttca gccttggacg tttctgtacg tgcccaagtc
    17221 ttgaacttgc tcaaaaaatt ccaaaaagag ctcggcctga cctatctctt catcgcccat
    17281 gacttgtcgg ttgttcgctt tatttcagat cgtatcgcag ttatttacaa gggtgttatt
    17341 gtagaggttg cagaaacaga agaattgttt aacaatccaa ttcacccata tactcaagcc
    17401 ttgctttcag cggtaccaat cccagatcca atcttggaac gtaagaaggt cttgaaggtt
    17461 tacgacccaa gtcaacacga ctatgagact gataagccgt ctatggtaga aatccgtcca
    17521 ggtcactatg tttgggcgaa ccaaaccgaa ttggcacgtt atcaaaaagg actaaactag
    17581 taatggtttt ataatttcca tgtcaatttt tatggaaatt aggctctttg tcaactgtag
    17641 tgggttgaag tcagctaagc tcgagaaagg acaaatttcg tcctttcttt tttgatgttc
    17701 aaagcgataa aaatccgttt tttgaagttt tcaaagtttc gaaaaccaaa agcattgcgc
    17761 ttgataagtt tgatgagatt attggtcgct tccagtttgg cattagaata gtgtagttga
    17821 agggcgttga taatcttttc tttatctttg aggaaggttt taaagacagt ctgaaaaata
    17881 ggatgaacct gcttaagatt gtcctcgata agttcgaaaa atttctctgg ttccttattc
    17941 tggaagtgaa aaagcaagag ctgatagagc tgatagtggt gtttcaagtc ttccgaataa
    18001 ctcaaaagct tgtttaaaat ctctttattg gttaagtgca tacgaaaagt aggacgataa
    18061 aattgcttat cactcagttt acggctatcc tgttgtatga gcttccagta gtgcttgata
    18121 gccttgtgtt catgggattt tcgatgaaac tgattcatga tttggacacg cacacgactc
    18181 atagcacggc taagatgttg tacaatgtga aagcgatcaa gaacgatttt agcattcggg
    18241 agtgaaacag tct
//
LOCUS       DAVLHM010000043        16864 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLHM010000043 DAVLHM010000000
VERSION     DAVLHM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.043"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            285..380
                     /locus_tag="VXE45_001668"
                     /pseudo
     CDS             285..380
                     /locus_tag="VXE45_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(633..1253)
                     /locus_tag="VXE45_001669"
     CDS             complement(633..1253)
                     /locus_tag="VXE45_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0789673.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1253..1735)
                     /locus_tag="VXE45_001670"
     CDS             complement(1253..1735)
                     /locus_tag="VXE45_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0789674.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1735..2577)
                     /locus_tag="VXE45_001671"
     CDS             complement(1735..2577)
                     /locus_tag="VXE45_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0789675.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2672..3472)
                     /locus_tag="VXE45_001672"
     CDS             complement(2672..3472)
                     /locus_tag="VXE45_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0789676.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3616..4995
                     /gene="glmU"
                     /locus_tag="VXE45_001673"
     CDS             3616..4995
                     /gene="glmU"
                     /locus_tag="VXE45_001673"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0789677.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            5005..5550
                     /locus_tag="VXE45_001674"
     CDS             5005..5550
                     /locus_tag="VXE45_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0789678.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5562..5876
                     /locus_tag="VXE45_001675"
     CDS             5562..5876
                     /locus_tag="VXE45_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0789679.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAAIFLLILLVLAMK
                     LL"
     gene            5893..6585
                     /locus_tag="VXE45_001676"
     CDS             5893..6585
                     /locus_tag="VXE45_001676"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0789680.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6662..7153
                     /gene="rocS"
                     /locus_tag="VXE45_001677"
     CDS             6662..7153
                     /gene="rocS"
                     /locus_tag="VXE45_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0789681.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7251..7841
                     /locus_tag="VXE45_001678"
     CDS             7251..7841
                     /locus_tag="VXE45_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0789682.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAD
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7850..9613
                     /locus_tag="VXE45_001679"
     CDS             7850..9613
                     /locus_tag="VXE45_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0789683.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9827..10472
                     /locus_tag="VXE45_001680"
                     /pseudo
     CDS             9827..10472
                     /locus_tag="VXE45_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            10639..10839
                     /locus_tag="VXE45_001681"
     CDS             10639..10839
                     /locus_tag="VXE45_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789684.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            10864..11280
                     /locus_tag="VXE45_001682"
     CDS             10864..11280
                     /locus_tag="VXE45_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789685.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLDVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            11511..12218
                     /gene="ccdA2"
                     /locus_tag="VXE45_001683"
     CDS             11511..12218
                     /gene="ccdA2"
                     /locus_tag="VXE45_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0789686.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            12229..12786
                     /gene="sdbB"
                     /locus_tag="VXE45_001684"
     CDS             12229..12786
                     /gene="sdbB"
                     /locus_tag="VXE45_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0789687.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            12907..14298
                     /locus_tag="VXE45_001685"
     CDS             12907..14298
                     /locus_tag="VXE45_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0789688.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            14441..15358
                     /gene="adcAII"
                     /locus_tag="VXE45_001686"
     CDS             14441..15358
                     /gene="adcAII"
                     /locus_tag="VXE45_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0789689.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            15366..>16864
                     /locus_tag="VXE45_001687"
     CDS             15366..>16864
                     /locus_tag="VXE45_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0789690.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         5236 a         2983 c         3554 g         5091 t
ORIGIN      
        1 tttcataata aaaacacccc aaaagttaga ttttttctgt ctaacttttg gggtgtagtt
       61 catgtacacc tgatatgatg cgttttataa ttttaaagac tttttgacca gcctcatttt
      121 tttaacttga tactcagtga aaagcaaaga ttaaactagg aagctagctg taggctgctc
      181 aaagaacagc tttgaggttg cagataaaac ttgtgaggtc accaacatat ataatgtgaa
      241 gctgacgtgg cttgaataga ttttagaagg gtatgagtct ggaagtttta atggataatg
      301 caagattcca tagaatgggt aagctagagt tcttatgtga agagtttggg cataaacttt
      361 taccttttcc tccctactca tcttagtata gaaaagtgaa tctaaaatag tacataactg
      421 cttctaaaac attcttataa attgatttaa attctcaaat catattattc agttcttatt
      481 tcattttgct ctacaatcct gttgagaaga cacgtgttca tatcaaaaag gtattggcaa
      541 gttgcaatac ctttttacaa ggttcttttg tcttattttt gtttcaactg actatatctc
      601 ctatggttct agttcagaag gctaggctat aattatgatt gataagaagt atcattccaa
      661 gtattgagag tgaatgtttc aaaatcatgg gtttctataa tggtcaggct ggcatttgct
      721 agaccgccat ctttacgaag aagtggttct ttatagccta ggagagtacg aagactggca
      781 gtaagattgg cgccgtgtcc gacaattaga atacgctcag ctggactatc ttttaatgat
      841 ttgataaatt ggatggtccg ttgagttgta ctatagaggg attcggctcc gaacattcga
      901 gtgtcaaatt gagcaagatt tgaacgaaaa gcctggattt gttgcgggta aatagcttcc
      961 aaggttgcaa ttttcaaacc ttctaacttc ccaagttgcc attcacggag attaggaacg
     1021 atttctaaag aacagggggt atagagttga ctttggataa tctcagcaga tttgaccgct
     1081 cgaggtaaat cacttgaata aatctgatca aaaggaattt ccttgagata ctggccaagt
     1141 cgttttaggg tttcaatgga ttcaggaaga agaggagaat caccgctagc accttgaaaa
     1201 cgaccttctt ggttccagag ggtacgaccg tggcggacaa agtagagttt cattacttga
     1261 tgtcctccaa aatatctaca aagtctgcct ttacaaagct agccaagtct tgtggcgcga
     1321 cgataatgct gtgtccgact tcgcctgcag agacaatcat tcgatccaaa tctagagcaa
     1381 ttttatcgat aaaaatggga taattgtgtt tctgacgaat tccgacagga ttattggctc
     1441 catgaatgta accagttgtt ttttctaagt ccttttgtgg aatcatgctc acttttttat
     1501 tgccagaaat tttagctagt ttcttttcag acaagtgctg agtgataggg acaattccga
     1561 taatcggtcc ggtcttgtct cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat
     1621 aaccttgagg aagctctcct tctagggcat tgatttgaat cccctgatga gggatagctg
     1681 ctttagatag gatttgttcc accaatgttt ttttgatttt aacttttttt gccattattt
     1741 atatttatcc tccaattgac tcatccaaat accaagccag attcccagcg caaagaagaa
     1801 ggcgatgatg acataaccga caagtgaaag tcctgtgtat tggatacttt cagcgtttcc
     1861 tgcatttgga attaagatca aaagggtact tgataggacg ataccgatga tgaaatgata
     1921 gacgcgtgag tggtagttgt ttaaggcata atccatcaat tttgaaaaaa cgatgagagt
     1981 tgcacctgca ccaattccaa tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc
     2041 agtcaacata ggagcataga gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg
     2101 aaccaagacg ccaagggcca atagtgcgcc tgctaggacg aagttaagaa agctggcgct
     2161 taaggttcca acgacaaaat ttaaggcata gagtcctaat ccagaaatga taaaggttgt
     2221 ccataaccaa gctaaatcaa tcttgtctcg gtcagattct cgagttgatt ctttgaggag
     2281 gctaggaact gtaccgataa tagctcccgc aaagctccat aatacaaaga cctgataatt
     2341 ttcaagcagg tattcaatcg ggtaggaaaa taagccgatt cccagaagca taccgatggc
     2401 aactggaata aagtacaaaa cattttcttt aaggtcttta aagggatggg ccagaaagcc
     2461 aatcattcgt tcatagattc ctaagattgc tgctagaacc cctccggaaa ttcccggtag
     2521 gataaatcca agagcaatta caatcccttt aataacgcgt gctaaccatg agagcatata
     2581 tttcctccaa ctatttctat ttcaaaaaat ccttactata ttgtatcaca atcagacaca
     2641 aaaagaaaaa gcaaatgata aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg
     2701 tttcttcttt attttttaag ggagagataa cgttgatatc taaatcgtgg tcaaagccgg
     2761 caatttttcc tttagatgtg tattggtgaa tatcataatc taaatcagtt ttaggactgc
     2821 tctccaaaaa tcctgagtct gagccgtagg acggaatcca aacagaggta aacttgcctg
     2881 tatcaatact gtgttcttcc atgaagtaga caccaacgta gatgccgatg tttttagcac
     2941 ctagtgatgc tagttttgct cgaaagtttt cgacaccttc gttcatatta gacatggttt
     3001 tgtcttccac gtcaagccaa tagtaactag ggctgtaagg agaggcagca ttgtagaaaa
     3061 cttcggcagc cttttccatt tcttggacac tttttccagc tacataagcg tagacagcaa
     3121 ctgggacatt ccgcttttga agttcagtga tatgactctt ataggccttg tctattccat
     3181 tgataaatga agcatcattt tcttttgttg tttgagcacc actgtgaaca cgaacaatag
     3241 cacctgaaat attttgtgag agggcatcgt agttgatttc ctcaggacgc tgccagccag
     3301 agaggtcaat aatcggtttg tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat
     3361 tggattttgt tttaaacgat tggctgtcat taagtgggcg attgatgatt aaaatgaaca
     3421 tcataatccc aaaaaaacta aataaaataa gtggatgaat ttgttttctc atatcttata
     3481 agtctaccct aaaaatcaaa aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca
     3541 ttttttcatt caagagtgcg gaatgatttg aaatatggta taataaaagg gaatttctac
     3601 agaaaagaga agattatgtc aaattttgcc attattttag cagcgggtaa agggactcgc
     3661 atgaaatctg atttgccaaa agttttgcac aaggttgcgg gtatttctat gttggaacat
     3721 gttttccgta gtgtgggagc tatccaacct gaaaagacag taacagttgt aggacacaag
     3781 gcagaattgg ttgaggaggt cttggctgga cagacagaat ttgtgactca atctgaacag
     3841 ttgggaactg gtcatgcagt tatgatgaca gaacctatct tagaaggttt gtcaggacac
     3901 accttggtca ttgcaggaga tactccttta atcactggtg aaagcttgaa aaacttgatt
     3961 gatttccata tcaatcataa aaatgtggcc actatcttga ctgctgaaac ggataatcct
     4021 tttggctatg gacgaattgt tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag
     4081 aaggatgcta cagattttga aaagcaaatc aaggaaatca acactggaac atacgtcttt
     4141 gacaacgagc gtttgtttga ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa
     4201 tactatatta cagacgtcat tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat
     4261 actttgaaag attttgatga aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct
     4321 gagtcagtta tgcgtcgtcg catcaatcat aaacacatgg tcaacggtgt tagctttgtc
     4381 aatccagaag caacttatat cgatattgat gttgagattg ctccggaagt tcaaatcgaa
     4441 gccaatgtta ccttgaaagg gcaaacgaaa attggtgctg agactgtttt gacaaacggt
     4501 acttatgtag tggacagcac tatcggagca ggagcggtca ttaccaattc tatgattgag
     4561 gaaagtagtg ttgcagacgg tgtgacagtc ggtccttatg ctcacattcg tccaaattca
     4621 agtctgggtg cccaagttca tattggtaac tttgttgagg tgaaaggatc ttcaatcggt
     4681 gagaatacca aggctggtca tttgacttat atcggaaact gtgaagtggg aagcaacgtt
     4741 aatttcggtg ctggaactat tacagtcaac tatgacggca aaaacaaata caagacagtc
     4801 attggagaca atgtctttgt tggttcaaat tcaaccatta ttgcaccagt agaacttggt
     4861 gacaattccc tcgttggtgc tggttcaact attactaaag acgtgccagc agatgctatt
     4921 gctattggtc gcggtcgtca gatcaataaa gacgaatatg caacacgtct tcctcatcat
     4981 cctaagaacc agtaggagcc tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa
     5041 atctatcaag gaccaatatt taaactggtc caagatcagg ttgaattacc agaaggcaag
     5101 ggaactgccc gacgggattt gattttccac aatggggctg tctgtgtttt agcagtaacg
     5161 gatgaacaaa aacttatctt ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac
     5221 gaaattccag ccggaaaatt ggaagtagga gaaaacacag cccctgtggc agctgccctt
     5281 cgtgaattag aggaagaaac agcctataca gggaaattag aactcttgta cgatttttat
     5341 tcagctattg gcttttgtaa tgagaagtta aaactatatt tagcaagcga tttgacaaaa
     5401 gtggaaaatc cgcgtccgca ggatgaggat gaaaccttgg aagtccttga agtgagctta
     5461 gaagaagcga aagaattaat ccaatcaggt catatctgtg atgccaagac aattatggct
     5521 gttcagtatt gggagttgca gaaaaaatag aggaggtcag tatgggtaaa tctttattaa
     5581 cggatgaaat gattgaaaga gctaatagag gcgaaaaaat ttcaggtcct cctttgctag
     5641 atgataatga ggaaactaag attttaccaa cctcttcttc ccgttttggt tatgccaatc
     5701 ctaaggatca tggttttagc caggaaacct tgaagattca ggtcgaacca tctattcata
     5761 aaagccgtcg tattgaaaat accaagagaa atgtcttcaa ttctaagttg aataaaatct
     5821 tatttgcggc catctttctc ttgattttgc ttgttttagc aatgaaactt ttgtaataga
     5881 aaaggaattg aaatgaaaat aggaattatt gctgctatgc cagaagaact ggcttatctg
     5941 gtccagcatt tagataatac ccaggagcaa gttgttttgg ggaataccta tcatacagga
     6001 accattgctt ctcatgaagt cgttcttgta gaaagtggaa ttggtaaggt catgtctgct
     6061 atgagtgtgg cgattttggc tgatcatttc caggtggatg cccttattaa tacgggttca
     6121 gctggggcag tagcagaagg tatcgctgtt ggggatgtcg tgattgctga caaattagcc
     6181 tatcatgacg tggatgtcac agcttttggc tatgcttatg gacaaatggc gcaacaaccg
     6241 ctttatttcg aatcagacaa aacctttgtt gctcaaatcc aagagagttt atctcaattg
     6301 gaccaaaact ggcatcttgg tttgattgct acaggagata gttttgttgc aggaaatgac
     6361 aagatagaag cgattaagtc ccatttccca gaagttttag ccgtggagat ggagggggca
     6421 gctattgctc aagcagcgca tgccctcaat ctcccagtct tagtcatcag agctatgagt
     6481 gacaatgcca accatgaagc aaacatcttt tttgatgagt ttattatcga agctggacgt
     6541 cgctctgccc aagtcttgtt gacctttttg aaggctttag attaagcgga aatttgacag
     6601 tttttctagc ttatgataag atttaagtaa agaaaagcta gaaaacgttt cagaggatat
     6661 tatgagtatt gaaatgaccg tcagtgagat tgcagaggtc ttaggattat ctcgccaagc
     6721 aatcaataac cgtgtcaaag aattaccaga agaagacaca gataaaaatg acaaaggggt
     6781 aacagttgtt accagaagtg gcttgattaa gctagaagaa atctataaaa aaacgatttt
     6841 tgaagatgag cctgtcagtg aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga
     6901 tgagaagaat gcagaaattc ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt
     6961 atcagaaaaa gacgagcaga tgcgtatcaa agaccgtcag attgctgaga aagacaaaca
     7021 attagatcag caacaacaat tgacccttca agccatgaag gatcaagaaa atcttaagct
     7081 agagctggac caagcaaaag aagaagtcca atccactaag aaaggctttt ttgctcgttt
     7141 atttggagga taatcaagga gctgtttagg ttaaatgcta acctgatggc ttcttttgtt
     7201 tgtgaatagt atagttgatt agaacagaga cagtagagga gaggtacaga atggaacgat
     7261 tagaagatta cattgctttt gacttagaat ttaatcagca cgaaggacaa acacacttga
     7321 ttcaagtatc ggcagtgcgt tttagagatg gtcgggaaat cgatgcctat gattcctatg
     7381 ttcataccag cgtccctcta aaaagcttta tcaatggttt gaccgggatt acagctgaga
     7441 ccttaaaaga tgctcctcca gttgagaaag tcttagaaga attccaagag tttgtgggtt
     7501 ctttgctgat gataggctac aatgctgcta aaagtgattt acctatttta gcagatcatg
     7561 gtttagacta tagccaacag tacaaggtgg atttgtatga tgaagctttt gaacgtcgga
     7621 gttcagattt acatggtatt gccaatctca aattgcaaac tgttgcctca tttcttggat
     7681 ttcaaggtca gtctcataat agtttagagg atgctcggat gacggcgcgt gtttacgaat
     7741 ccttcttaga gtcggatcaa gctagggaat tgttagagac agaaagtagc ttatcaaaca
     7801 atccttttgg tgtcttggac ttgtctcaat tatttgacta ggagtgccta tgaaacctga
     7861 aaaacctaaa aaattgggtc ttaaacagat ttacctcaat cttgataaaa tcctctttct
     7921 atttttcttg atttttatga tagtggagta tttgtgggta ccattcaatt catggttggc
     7981 tagcttctta ttagatcaga caggttatct ttttatttcc tataacaatg tcttagccat
     8041 ccttactcat tctccattga ttagtctagc ttttttagcc ttgattgtaa ttaaccttct
     8101 ggttgcttat tttcaaatag gactcctctt tattggtgct cgtcatctcc tctataatga
     8161 aaagcgaagg ctaattgagt atatccgcaa ggttttccat gaaagttttg gatttatgaa
     8221 aaagctaact tgcgctaaag ccttgtttat ctttttctat atagctatgc tttttccttt
     8281 tatacggaaa atgctgaaga tttattatct taataaaatc gtcattccag agtttatcca
     8341 agcttattta gaagataaat attggatgtg gtggctgagc atcctacttc tatctcttat
     8401 ctttctctat gtctctgtca gattgatgtt tgcccttccg aagattgtat atgatcagct
     8461 gactgttcga gaagcagtga tgtttagctt ggagaaaacc aagaagagag ttacttttta
     8521 tgcttggaat ttattttaca tcttgctcaa agcacattta ttattttatc ttcctttgat
     8581 tcctttatta ttggctcaaa ctttggtaga tgatatcact cagagagagt ctctgattct
     8641 tggtattttg aattttgtcg tgattaaaaa tctctattat atggctctga cttatttttt
     8701 ggttaaattt gtttcatttt tgacaggaaa ggagctggat atgcttccta ggagagaaaa
     8761 agatcacatc gtgcgatggg gtgtcatgac ttgtgccagt cttttctttg ccttagaagg
     8821 ttatatttat ctggaggctc ccatggttca tctacctcaa cttatttctc accgaggggt
     8881 ttccaatgca aatgggattc aaaatacagt agagtccttg gaaactacag cacaactcaa
     8941 accagacttg gtggagacgg acgtgcagga aacaaaagat gggcagtttg tcatgatgca
     9001 tgatgctaac ttgaaaaatc tagcaggtat caataaaagt cctcaagact taaacttgga
     9061 ggagcttaaa gggattgata tttttgaaaa tggctaccag actaaaattt caagctttga
     9121 agattatctc agtcgagcca acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag
     9181 taaaaaagat agtccagaca tgatgaaccg ctttttagcc cgttatgctg caaagctcaa
     9241 gatttatgga catcaaatcc agtctttaga ctaccatgtt gtcgaaaaag taagacagta
     9301 tgatgccgaa ctgccagttt atttcatcat gccctacaat tctgtctttc ctaaaacaag
     9361 agcgacagga tatactatgg agtactcaac cttggatgaa tattttgtaa gcaaactatg
     9421 gacaacggat cagaaacttt atgtctggac tgtcaatgat tcagaagcta tcagcaaatc
     9481 tcttcactta ggagtagatg gagtgattac agatgatttg gaaaaagttc agcgggaaat
     9541 agaagtagcc caagaagatc cagaatatac ggatttgctc ttgaaaaaag cattggaatt
     9601 ctttgaattt tagtaataaa aaagaggaac ggttgttcct cccatgatag gtaagtattc
     9661 ttgtgaatgc ttgctttttt gtggttgcaa tccgtttacg agaattgttt gtattgttct
     9721 tgtttcaatt tactttatag tgctttgaag ttggaatgct acactataac ttctaaaata
     9781 tagtaaaatg aaccaaaaat agtacacaat gtggtataat cttcttatgg catattcaat
     9841 agattttcgt aaaaaagttc tctcttattg tgagcgaaca ggtagtataa cagaagcatc
     9901 atacgttttc caaatctcac gtaatactat ttatggctgg ttaaagctaa aagagaaaac
     9961 aggagagcta aaccaccaag taaaaggaac aaaaccaaga aaagttgata gagatagact
    10021 taaaaactat cttactgaca atccagacgc ttatttgact gaaatagctt ctgaatttgg
    10081 ctgtcatcca actaccatcc actatgcgct caaagctatg ggctacactc gaaaaaagaa
    10141 ccacacctac tatgaacaag acccagaaaa agtagcctta tttcttaaga attttaatag
    10201 tttaaagcac ctagcacctg tttagattga cgaaacagga ttcgatactt atttttatcg
    10261 agaatatggt cgctcattaa aaggtcagtt aagaagaggc aaagtatctg gaagaagata
    10321 tcagagaatt tctttggttg caggtctaac aaatgaatgg tgagttaatc gctccaatga
    10381 cttacgaaga gacgatgacg agcgactttt ttgaagtatg gtttcagaaa tttctcttac
    10441 caacattaac cacaccatcg gttattatag taaaatggaa taagaacagg acaaatcgat
    10501 caggacagta aaatcgaatt ctaacaatgt tttagaagtc tatatgtact attctagttt
    10561 caatatacca taactgctcc tagtcaacct gcaagtcctg tcccagctcc aagctcagct
    10621 ccgactcaag atcctagagt ggtagcaagc gcttcggcta gctcaacgag cacacaagct
    10681 caagagcaag ttgacaagtc tgaacttcgt gccttgagtc aagagttaga ccaacgcttg
    10741 aaagctttgg caacagtatc tgatccaaaa atcgatgcaa ccaaggctgt cctcctagat
    10801 gctcaaaaag ctccggaaga tagtgccttg acagagtaag gtctgcatac tgcagtagag
    10861 tctgtgaagg ctgccttgga ctctctcaaa gatgtgaaag caaatgctag cgacagcaag
    10921 cctgcacagg acaagaagga tgcaaaacaa ggaacggaag atagtaagga ttcagataag
    10981 atgactgaaa caaactcagt tccggcagga gtgattgtgg tcagtctact tgccctccta
    11041 gacgtgattg ccttctggct gattcgccgt aagaaagagt cagaaatcca gcaattaagc
    11101 acggaattga tcaaggttct aggacagcta gatgcagaaa aagcggataa aaaagtcctt
    11161 gccaaagccc aaaaccttct ccaagaaacc cttgatttcg tgaaagaaga aaatggctca
    11221 gcagagacag aaactaaact agtagaggag cttaaagcaa tccttgacaa actcaagtaa
    11281 aacatgattt atgaaatgtc agacctaaaa gacattttcg ttcacaaaag cagtgacgag
    11341 taatccttgt cgttgctttt tggctatttt gggggataag atccgccttg actagcaaaa
    11401 gaaaagattg gtccaatagt gcccgatacg attttgcgta gcagaaagct tacaaataaa
    11461 attgaatata gtaaaatagg attagaatta ttaagaaagt tggttcttta ttggaaacga
    11521 tagtattttt aatctctgtt tttctagcag gtgttttatc ctttttttct ccttgtattt
    11581 ttcctcttct gccagtctat gctgggattt tattggatga tcaagaaagt gcaaaaagct
    11641 tttctttgtt tgggagaaag gttctctggt caggcttgat tcgaacactt tgctttatcg
    11701 ctggtatctc tctcattttc tttattctag gctttggtgc tggttacttt ggtcatattc
    11761 tctatgcaaa ttggtttcga tatgtcatgg gagctattat tatcattttg ggtcttcacc
    11821 agatggaaat ttttcatttg aagaaattag aagttcaaaa aagttttacc tttaaaaaat
    11881 cagattctaa tcgttattgg tcagcttttt tacttggtat tacctttagc tttggttgga
    11941 caccttgtat tggtccagtt ttaagttctg ttttagcact tgcggcttct ggaggcaatg
    12001 gtgcttggca aggagcgatt tatactctca tttacactct gggcatggcc cttcctttct
    12061 tggtcttggc actagcttca ggtctagtca tgccatattt tagtaaaatc aagcgtcata
    12121 tgatgctact aaagaaaatt ggtggtttcc tcattgtttt aatgggaatt ttgttactat
    12181 taggacaagt aaatgttcta gctggaattt ttgaataaag gaggacaaat gaaaaaagta
    12241 atgtttgctg gcttaagtct cttgtcatta gttgtattga tggcctgtgg tgaggaagaa
    12301 actaaaaaga ctcaagcagc acaacagcca aaacaacaaa cgactgtaca acaaattgct
    12361 gttggaaaag atgctccaga cttcacattg caatccatgg atggcaaaga agttaagtta
    12421 tctgatttta agggtaaaaa ggtttacttg aagttttggg cttcatggtg tggtccatgc
    12481 aagaaaagta tgccagagtt gatggaacta gcggcgaaac cagatcgtga tttcgaaatt
    12541 cttactgtca ttgcaccagg aattcaaggt gaaaaaactg ttgagcaatt cccacaatgg
    12601 ttccaggaac aaggatataa ggatatccca gttctttatg ataccaaagc aaccaccttc
    12661 caagcttatc aaattcgaag cattcctaca gaatatttaa ttgatagcca aggaaagatt
    12721 ggaaagattc aatttggtgc tatcagtaat gcggatgcag aagcagcatt taaagaaatg
    12781 aactagaatc gataaaatct gattacaaga tgtagtcaga tttttttaga aaaacatttt
    12841 ataaatattc acatatctcc tatatttatg gtaaaataga attatcagtt tattttggag
    12901 tcaaagatga atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg
    12961 catttgaagt tatgggattt gattttgctg ggtatcggag ccatggtagg gacaggcgtc
    13021 tttacaatca caggtactgc agctgcaaca cttgctggcc cagccctagt gatttcaatc
    13081 gttatttctg ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga
    13141 gtacccgcta caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc
    13201 tggttggctg gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg
    13261 ggttgggcag cttattttaa aggcttgctc tctcaatacg ggatagcctt tcctcaggct
    13321 ttaaatggta cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc
    13381 ttggtcttgg tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg
    13441 attctagtta ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat
    13501 attaagtttg ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct
    13561 agcactggta ttatggctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc
    13621 atctctatgg ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc
    13681 ttatcgcttt ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg
    13741 gttcactata gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg
    13801 attagttggg cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt
    13861 atttcgatga cctatgccct atcgcgtatg atttacagtt tagcacgtga cggcttagtg
    13921 cctgctgcct ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg
    13981 acaggtctag cttcagcagt agcagcagga atgttcccac tagccagtat tgcagccttt
    14041 ttaaatattt gtaccttagc ctacttgatc atgctggctt atggtctgat tcgcttacgg
    14101 aaagaaaaag gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca
    14161 attttatcga tcatcatttg tttatccttc atgttacagt ataatatgaa cacctggatt
    14221 gctttcctag ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat
    14281 tctaccatag aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat
    14341 atgtgaaaga aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt
    14401 agaatattta ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt
    14461 tttagtcctg ttaagtgtct ttcttttgtg tttgggggct tgtggtcaaa aggaaagtca
    14521 gacaggaaag gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga
    14581 agtatctggt gacttgaatg atgttcggat gattcagtca agtagtggga ttcactcctt
    14641 tgaaccttcg gcaaatgata tcgcagccat ctatgatgca gatgtctttg tttaccattc
    14701 tcatacactc gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa
    14761 ggtcttagag gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga
    14821 agcaggggat ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga
    14881 aaaagctgga gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca
    14941 taaagagact tatcaaaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa
    15001 gaaattccaa ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc
    15061 cttttcttat ctagcgaaga gatttgggct taatcaactt ggtattgcag gtatctctcc
    15121 tgaacaagaa ccaagtccac gacaactaac agaaattcag gaatttgtta agacctataa
    15181 ggttaaaacg atttttacag aaagtaacgc ttcttcaaaa gtagctgaaa ctcttgtcaa
    15241 atcaacaggt gtgggtctta aaactctgaa tcctttagag tcagacccac aaaatgacaa
    15301 gacctattta gaaaatcttg aagaaaatat gagtattcta gcagaagaat taaagtgagg
    15361 aaagaatgaa aatcaataaa aaatatctag caggttcagt ggcagtcctt gccctaagtg
    15421 tttgttccta tgaacttggt cgtcaccaag ctggtcaggt taagaaagag tctaatcgag
    15481 tttcttatat agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag
    15541 tcagtaagag agaggggatc aacgccgaac aaattgttat caagattacg gatcaaggtt
    15601 atgtgacctc tcatggagac cattatcatt actataatgg caaggttcct tatgatgcca
    15661 tcatcagtga agaacttctc atgaaagatc cgaattatca gttgaaggat tcagacattg
    15721 tcaatgaaat caagggtggc tatgtgatta aggtagacgg aaaatactat gtttacctta
    15781 aagatgcagc ccatgcggac aatattcgga caaaagaaga gattaaacgt cagaagcagg
    15841 aacgcagtca taatcacaac tcaagagcag ataatgctgt tgctgcagcc agagcccaag
    15901 gacgttatac aacggatgat gggtatatct tcaatgcatc tgatatcatt gaggacacgg
    15961 gtgatgctta tattgtccct cacggcaatc acttccacta tattcctaag agtgatttgt
    16021 ctgccagtga attagctgct gcccaagcct attggaatgg gaagcaggga tctcgtcctt
    16081 cttcaagttc tagtcataat gcaaatccag ctcaaccaag attgtcagag aaccacaatc
    16141 tgactgtcac tccaacttat catcaaaatc aaggggaaaa catttcaagc cttttacgtg
    16201 aattgtatgc taaaccctta tcagaacgcc atgtagaatc tgatggccta gtatttgatc
    16261 cggcacaaat aacatatcgt acagtcaatg gtgttgctgt accgcacgga gaccattatc
    16321 actttattcc ttattcacaa ctgtcacctt tggaagaaaa attggctcgt atgattgctg
    16381 ttaagggaca aaatggtgca gtcttgccag gaatgcatta tttgaaacca gcaccaaaac
    16441 cgcaagttca accatcaact gagaaaaaac aaactgattt tgcagtagaa caggttgtta
    16501 gaaaagttgg agaaggctat gttgtggaaa ttgctggtgt cagtcactat gtttttgcta
    16561 aagacttggc taaggataag attgatgcta ttgaaaatct cttgtctaag aaaactcaag
    16621 agacacatgc tctagttgct aaaaaagaaa atgtcgctcc tcgtgaccaa gaattttatg
    16681 ataaagctta caatctgtta acccaggctc ataaagtctt gtctgaaaat aaaggtcgta
    16741 cttctgattt ccaagcctta gacaaattag cagaacgctt gaataatgaa tcttctaata
    16801 aagtaaaatt ggtagatgat ttattggcat tcctagcacc aattacccac ccagaacgcc
    16861 ttgg
//
LOCUS       DAVLHM010000044        16803 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLHM010000044 DAVLHM010000000
VERSION     DAVLHM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.044"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..1133
                     /locus_tag="VXE45_001688"
                     /pseudo
     CDS             1..1133
                     /locus_tag="VXE45_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VXE45_001689"
     CDS             complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VXE45_001689"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0789691.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3025..3723
                     /locus_tag="VXE45_001690"
     CDS             3025..3723
                     /locus_tag="VXE45_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0789692.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3766..4662)
                     /locus_tag="VXE45_001691"
     CDS             complement(3766..4662)
                     /locus_tag="VXE45_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0789693.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQTDIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4671..5606)
                     /locus_tag="VXE45_001692"
     CDS             complement(4671..5606)
                     /locus_tag="VXE45_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0789694.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5603..6328)
                     /locus_tag="VXE45_001693"
     CDS             complement(5603..6328)
                     /locus_tag="VXE45_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0789695.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(6412..7047)
                     /locus_tag="VXE45_001694"
     CDS             complement(6412..7047)
                     /locus_tag="VXE45_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0789696.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7049..7876)
                     /locus_tag="VXE45_001695"
     CDS             complement(7049..7876)
                     /locus_tag="VXE45_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0789697.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDIIQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7898..8233)
                     /locus_tag="VXE45_001696"
     CDS             complement(7898..8233)
                     /locus_tag="VXE45_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV0789698.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(8234..8950)
                     /locus_tag="VXE45_001697"
     CDS             complement(8234..8950)
                     /locus_tag="VXE45_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV0789699.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHL
                     YVVEPSETIEKDGDKKLIVY"
     gene            complement(9093..9284)
                     /locus_tag="VXE45_001698"
     CDS             complement(9093..9284)
                     /locus_tag="VXE45_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789700.1"
                     /translation="MKEILICDIIKRKGLHKKVGRMKMQRRQNRNQGGLAFRFMKGLV
                     NFLGVIASGAIRDLWRYSC"
     gene            9473..10084
                     /locus_tag="VXE45_001699"
     CDS             9473..10084
                     /locus_tag="VXE45_001699"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0789701.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10129..10857
                     /gene="rlmB"
                     /locus_tag="VXE45_001700"
     CDS             10129..10857
                     /gene="rlmB"
                     /locus_tag="VXE45_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0789702.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VXE45_001701"
     CDS             complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VXE45_001701"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0789703.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11873..12097)
                     /locus_tag="VXE45_001702"
     CDS             complement(11873..12097)
                     /locus_tag="VXE45_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0789704.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12175..12918)
                     /locus_tag="VXE45_001703"
     CDS             complement(12175..12918)
                     /locus_tag="VXE45_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0789705.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12918..13718)
                     /locus_tag="VXE45_001704"
     CDS             complement(12918..13718)
                     /locus_tag="VXE45_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0789706.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13876..14232)
                     /locus_tag="VXE45_001705"
     CDS             complement(13876..14232)
                     /locus_tag="VXE45_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0789707.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14226..14756)
                     /locus_tag="VXE45_001706"
     CDS             complement(14226..14756)
                     /locus_tag="VXE45_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0789708.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(14756..15250)
                     /locus_tag="VXE45_001707"
     CDS             complement(14756..15250)
                     /locus_tag="VXE45_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789709.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15385..15831
                     /locus_tag="VXE45_001708"
     CDS             15385..15831
                     /locus_tag="VXE45_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0789710.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15828..16475
                     /locus_tag="VXE45_001709"
     CDS             15828..16475
                     /locus_tag="VXE45_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0789711.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILTASVLQYIAIVYYM"
BASE COUNT         5058 a         3790 c         2972 g         4983 t
ORIGIN      
        1 tctaaaattc cttatcttga aacgactggt atgccttcta gaattctcct tagaaaacgc
       61 cgtttcaagt gctatcactg ttcaaaaatg atggttgctg agactcccct ggtaaagaag
      121 aatcaccaaa tccctcgtat catcaaccaa aaaattgctc aaaagttaat tgaaaagatt
      181 tctatgactg atattgccca tcagctttcc atctcaactt caactgttat tcgtaagctc
      241 aatgattttc actttaaaca tgatttttcg cgtcttcctg agattatgtc ttgggatgag
      301 tatgctttta caaagggaaa gatgagcttc attgcgcaag attttgaaaa gctcgatatc
      361 atcactgttc ttgagggtag aacacaagct atcattcgaa atcactttct tcgctacgat
      421 agagttgtcc gatgtcgcgt caaaattatt actatggata tgtttagccc ttactatgac
      481 ttagctagac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc tcccagactg
      541 tttcactccc gaatgctaaa atcgttcttg atcgctttca cattgtgcaa catcttagcc
      601 gtgctatgag tcgtgtgcat gttcaaatca tgaatcagtt tcatcgaaaa tcccatgaat
      661 acaaggctat caagcgctac tggaagctca tacaacagga tagccgtaaa ctgagtgata
      721 agcgttttta tcgtcctact tttcgtatgc atttaaccaa taaagagatt ttagacaagc
      781 ttttgagcta ttcggaagac ttgaaacacc actatcagct ctatcagctc ttgctttttc
      841 acttccagaa taaggaacca gagaaatttt tcggacttat tgaggacaat ctgaagcagg
      901 ttcatcctat ttttcagact gtctttaaaa ccttcctcaa agataaagaa aagattatca
      961 acgcccttca actaccctat tcaaacgcca aattggaagc gaccaataat ctcatcaaac
     1021 ttatcaagca caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttta
     1081 tcgctctgaa tatcaaaaaa gaaaggacga aatttgtcct ttctcgatct tagcttttct
     1141 tcaacccact acagttgaca aagagcctga aaactacggt ctaatttttt gtccaaatgt
     1201 aaaccacttg gaactattat tcaatttatt ctttttagca aatgttcccg ttttaatccc
     1261 agttacagtt tttaatcctt tgtaaccgtt gattttacaa agcttttaat ttttttgcga
     1321 ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga tacggttaac
     1381 atgatccact tcatttacga tacgtactga gattttttga agtacttccc atggaatttt
     1441 ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa tcgtgtagtc
     1501 atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa cagtgaagta
     1561 ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa tagcgtctga
     1621 ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga tagcaagtcc
     1681 tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct ctgtaccaag
     1741 agcacgaact tcatccttgt aaagagtatt gagtggttca atcaattcaa actgcatatc
     1801 ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat ccgtaccaga
     1861 ctcgataaca tctgtatata aagtaccttg agcaaggaat ttcacatctt tgagcttgct
     1921 tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt tttgttcagg
     1981 gtcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt tgacgatatt
     2041 caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt tacgaagaag
     2101 accgtggtcc acgaagatac agatcaattg atcgccaatc gctttttgga gaagaacccc
     2161 aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat caccgacggt
     2221 ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt cacctttagc
     2281 cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag aatgacgaac
     2341 ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg ctgcgtatgg
     2401 gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa ccgcatcacc
     2461 atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg atggtgtgtg
     2521 agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa caacttttcc
     2581 tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg gaattccgag
     2641 ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat ttggaccacc
     2701 tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa ttttatggct
     2761 ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct ggttgtactg
     2821 gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg aaatgttgct
     2881 catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca aataagggcg
     2941 aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt acaatagaga
     3001 aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca tgatcagata
     3061 aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag tgaaagagat
     3121 ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc tctattagtc
     3181 gaagaaggcg tcttagagcg ccatgtagga agcggcacct ttgtttccag tactcgagta
     3241 caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca aggtaaagtt
     3301 ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga agttgccaag
     3361 ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta tgccgaccaa
     3421 gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga ctttaaaaaa
     3481 gaagaaatca ccagtcattt cttccaaacc ttgcaaaaac atggctatcg tatcggcaaa
     3541 tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta tttggaagtt
     3601 gaaaaaggac atgctattct tggattgacc caggtttcct acctagaaga tggtactgct
     3661 tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct tgaaaataat
     3721 tagattacca cgcaaaaact ctctgtcacg gacaaagagt cttttttatt tttctaagaa
     3781 taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac caagaaaatc
     3841 aatgggataa aattgttcat tcattattaa gaaggcaaag aaaatcgccg atattggctc
     3901 aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt taaggaaagc
     3961 tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga gaaaatcaag
     4021 actagtcggg atatcggtct gtagaacccc tgtaaaagga agggcgacca aacctgctat
     4081 gaccattccc acaccaatga ccaagctgct cccccacttt ttaatcaagg ctatgggtaa
     4141 aatgatatac agagcataag tcaaggcaga aaagagaccc cagaacagac cagcaggtgt
     4201 catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc cgatggcgaa
     4261 tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac agctataaat
     4321 taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat tggtctcctg
     4381 aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa aaataagaag
     4441 agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg cagtagcata
     4501 agccaagagc atgagaattc caccagcgat taaaagacgc aagttggtca agaccagagc
     4561 cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc aagcaatacc
     4621 agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc ttactcttct
     4681 ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct ctcgtccttt
     4741 tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt ccacatgata
     4801 aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca tgctaaagaa
     4861 cgttccttgt catccaaagg agaaaaattt tgacttaagt ctcttgcaaa atcatctgct
     4921 aaatagtgtt ctaaaaagat ttgtaaatcc tttatagtcg aaaataaacc agcgctccca
     4981 gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc tacacctcta
     5041 actgttggaa cagcaagctc aactggccca aacttggttt ccgtcattcc ccaaggtttc
     5101 cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc caaaataaag
     5161 cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg tctgttgaga
     5221 tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg aataaaagga
     5281 tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata atcactctca
     5341 ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca caagaaggta
     5401 caaactgtgc caaccccaac aaccttgctg acactagcta ggtcataaac tagtcctgcc
     5461 tcagtctgca agccatgctc tgggtcactc tggcctaaat agaactctgt ccattgattg
     5521 tccttaaaat acgcaaaaga ggctccggga taaattcctg cctcgatttg ttcttctatt
     5581 tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca ttatttctat
     5641 ctttacaaag gaagaatttt tcagacttag gaataaaata ttcagtagac tcaaacttct
     5701 ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat aagtcccagg
     5761 taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca agggatgccc
     5821 caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat tccatagaaa
     5881 tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc ttttctccta
     5941 cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca tcttctggtg
     6001 agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc gaatctgttt
     6061 tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat ctagctagtt
     6121 tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa accagctttt
     6181 caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag gccttcattc
     6241 caagggtttc aatataaaat gtttcattta attttctatt attagctttt aaagtaggaa
     6301 taatccgtac aatctgattt acattcataa attcctccgt cactttttat tttaaaggat
     6361 tttagaattt tttacaagat attatgctca aatttaacat tatttagcta tttagtaaag
     6421 atagtctttc aaggattttg acaaagcctg ataaccagca atactgaggt gcagtccatc
     6481 agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa atactggcac
     6541 aaattccacc tgcatatagg cagatgcaag ctcttgatag gcttgattcc agttctgaat
     6601 tttttcattc gagcggatat agactgcctg ctggtactcc tctccctcat tgacaggcaa
     6661 aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt gaatgatagc
     6721 ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat ttgtcccaat
     6781 cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaagat tctctagtaa
     6841 cagtcctgtc tgatagccac gaattcctcg attgacaatc gtctttgaag tcccaaatag
     6901 ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt ttggttctac
     6961 aacagaaatg tgatttaggt gacgatactt agtttgaatt ttttcttgtt cctttaggag
     7021 ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag ttttccaaga
     7081 cttgataaac tcctccttgg ctgttggctg gtgctagagc agtcgccaca gctttggctt
     7141 tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt tcaacatcat
     7201 tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc ttgagtaatt
     7261 cctccaagcc ccatgcttta tgaatcccag cttggatgat atcaatgcaa ccatagccac
     7321 tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa accgaactca
     7381 aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg tcagatgtta
     7441 attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga gtcataaaac
     7501 tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc cccgttacaa
     7561 caaactggtc ctgacacgct cgaaccttga aatgagtcaa agccttgttg acaatggcgt
     7621 catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg ccattagcaa
     7681 caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg tgaatttcat
     7741 tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa atcttttcca
     7801 atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata tctgtcgcaa
     7861 ttaccttaat catcatttac tttcctctgg attcaagcta ataccacttc aatcccacat
     7921 gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca tctaactggt
     7981 cacgatgact gccatcctct ataaaatctt ccaaaatata agtttggtaa tgatacaagg
     8041 gatatccttc tggtgaaaag gttccctttg gtgttcgatt gacccaagta ggatgagctt
     8101 tagctgttcc gatagttgtt tttccatcct tcttcttgat ggtgacatcc atgagaacac
     8161 cacgttcagt ccacttagca ttctcttcat ctcccataga ttcaattcgt tgattggaaa
     8221 tgaagttccc catttaatag acaatgagct tcttatctcc atctttttca atcgtttcag
     8281 atggttcaac aacgtaaaga tgccctccaa agataatatc cgctccccaa tcgatcatct
     8341 tgtgataaag agctttttgt tcttcagttg gttccaatcg atactcaaca cccatctgag
     8401 gcatgataat ggtgatatct gcttccttct ctgcccgttc aatttcagcc ttcatcttat
     8461 cttcgtttaa atctgaaaga taacgattat agtcttcctg agaaatatac tgctcaattc
     8521 cattgaaacc ataggaatag gctaacaatg caaccttgat accattcact tccttaatga
     8581 ccagcggagc ctgatcacgt ggttcgtgcg tataaactcc gattggagtg attccagctt
     8641 tctcaataat atcggccgtt gaaataactc cctcaatttg cgaatccaaa atatgattat
     8701 gagctaaatc cagcacatga taacctgcct ccttaatagc atccataact tcagcaggag
     8761 cattaaagag aggataaccc gctaaataat gatccttatt aatggtttct tcaaaatcac
     8821 caatagctaa atctgcttgc ttgaaccaag gagtcacata ctcaaaattt tcatgaaagt
     8881 cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc
     8941 cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt tgcttagttc
     9001 cctcttgaga aatagtatct cgtttttgac tagtcaagag attccttgga agctttcaaa
     9061 caataagacc aagcccattg ataaaccaac tgctagcaag agtatcgcca caaatccctt
     9121 attgctccac ttgcgataac tcctaaaaag tttaccaagc ccttcataaa acgaaaagct
     9181 aaaccaccct gatttcgatt ttgtcttctt tgcatcttca ttctccctac tttcttatgc
     9241 aagccttttc tttttattat atcacagata agtatttctt tcacaattga attgaacttc
     9301 ccatctattt tctataaatc ctaaatgcca taatgctttc aattcttgtc attttgtgat
     9361 atcatgtaga ggtaatgaaa ggaaatgaac taatccacag tggcttattc caagtatacc
     9421 acttgggctt tggcagtagt taactgcact aaacataata taaggagaga aaatgtctgc
     9481 aatagaacgt attacaaaag ctgctcactt aattgatatg aacgatatta tccgtgaagg
     9541 gaatcctact ctacgcgcga ttgctgagga agtcactttc cccctatctg accaggaaat
     9601 catcctaggc gaaaagatga tgcaattcct taaacattcc caagatcctg tcatggctga
     9661 aaaaatggga ctccgcggtg gtgttggact ggctgctccc cagttagata tctcaaaacg
     9721 cattatcgct gttttggtac ctaatattgt tgaagaaggc gaaactccac aggaagccta
     9781 cgatttggaa ggcattatgt acaatccaaa aatcgtctct cactctgttc aagatgctgc
     9841 tcttggcgaa ggagaaggtt gcctgtctgt tgaccgtaac gtgcctggct atgttgttcg
     9901 ccatgcccgc gttactgttg actactttga caaagatgga gaaaaacacc gtatcaaact
     9961 caaaggctac aactccattg ttgttcagca tgaaattgac cacattaacg gtatcatgtt
    10021 ttacgatcgc atcaatgaaa aagacccatt tgcagttaaa gatggtttac tgattcttga
    10081 ataaagaaaa tcccgttgca agacggggtt ttgtgttata atagaggcat gaaaacaaat
    10141 gatattgtct atggtgtcca cgccgttacc gaagccctcc ttgcaaatac aggaaacaaa
    10201 ctctacctcc aagaagatct ccgaggtaag aatgttgaga aagtcaagga actagctaca
    10261 gaaaagaagg tgtccatttc ttggacatca aaaaaaaatc tctctgagat gactgaaggt
    10321 gctgttcatc aaggttttgt tctacgagtg tctgaatttg cctatagcga gctagattac
    10381 atccttgcaa aaacacgcca agaagaaaat tcacttctat tgattctaga tggtctaacc
    10441 gatccccata atctgggttc tatcttgcga acagccgatg cgaccaatgt ttcaggtgtc
    10501 atcattccca agcaccgtgc tgtcggagta actcctgtcg ttgccaaaac agccacaggt
    10561 gctattgaac acgttccaat tgcccgagta accaacctca gtcaaacctt agataaactc
    10621 aaggatgaag gtttctggac ctttggaacg gatatgaacg gtactccttg ccacaagtgg
    10681 aatacaaaag ggaaaatcgc cctcatcatt ggaaatgaag gaaaaggtat ctctagcaac
    10741 ataaaaaaac aggtcgatga aatgattacc attccgatga atggacatgt tcaaagcctt
    10801 aatgccagtg ttgctgcggc cattctcatg tacgaagttt tccgaaatag actataaaaa
    10861 agtttccagt catctgattg gaaacttttt tatgattaac tatgttctgt aatgaattta
    10921 taggcttctt gaccagcgat agctccatct ccaactgctg ttgttacttg gcgaaggtct
    10981 ttcaagcgaa catctccaac tgcaaagata ccgtcgactg cagtcttcat gtggctatct
    11041 gtcacaatcc agcctgcctg atcttggata ttcaattctt taacaaaatc gctaagaggg
    11101 tccaaaccaa catagataaa gacaccaccg aaggcttgct ctgtcacttg acctgttttc
    11161 acattttcaa aaacgacaga ttctactctg ttttcaccct tgattttcct tactacagaa
    11221 tcccatataa agctgatttt ctcattggca aaggcgcgat cttgtaaaac cttttgggca
    11281 cgaagttggt cacgacggtg aacaatggta acagtcttag caaaacgagt caagaagagg
    11341 gcttcttcaa cagctgaatc tccaccacca actaccaata aatcttggtc acggaagaaa
    11401 gcaccatcac acacagcaca gtaagaaaca ccacgactgt tcagttcttc ttctccaggc
    11461 actcccaaag gacggtgttt agaaccagtt gctacgataa ctgtacgtgt ttcatatgtt
    11521 tggtcatcag tcatcacttt cttaaaatca ccatggtctt cgacattttc aacataacca
    11581 taaatgtgct caacaccaag attttcaagt ggttcaaaca tcttttcagc caattcaggt
    11641 ccactaatat tagcgtatcc tgggtaattt tcgatatcag atgtattatt catctgacca
    11701 cctggcagac caccttcaat caaagctact tttagattgc ttcgagcagc atacaaggcc
    11761 gcagtcatcc ctgcaggtcc agcaccgata ataatagtat cgtacatata gattccttct
    11821 ttcttgttgt aactatcttt attctaactc tttcttgtca atcacgcaag gattatgcct
    11881 tgaaaacaag aattaaactc ataaccgcaa aggataatac tgggacaacc aagactccaa
    11941 tcataatcat atcatagaga tgggcttggc gagccttggc tgtcttatca actcccgaca
    12001 tggctctcag accaatccaa atccctaaaa aaatcagaac aaggatggtg gtcaagatca
    12061 aactctcgaa atataaagaa aatagttgca gtagcatgat ttctctcatt tctatctttt
    12121 ttaaagagta aactcagcta gtccaactaa ctgagttttc ctttatctat tatatcaaat
    12181 ataagtccgt ttgtaactag cgaagaattc ttttgtccgc tcttctttag gggtgtggat
    12241 aatctcatcc ggagttccag actcgatgat tttcccctta tctaagaaga gaatcttatc
    12301 cgcaacttgg gctacaaagg acatgtcatg actgaccaaa atcatggtct gacctgactt
    12361 agcagcatct gcaatagact tttctacttc accgaccaat tctgggtcaa gggctgaagt
    12421 tggttcgtct aagagcaaaa catctggttt catagcaagc gcacgcgcta gggcaacccg
    12481 ttgcttctgt ccacctgata aatggcgagg ataatggttt tcacggtccg aaagcccaac
    12541 cttagccaac tcttccttgg caatcttagt cgcttcttgg tcagataatt tcttgacaac
    12601 aaccaagcct tctttcacat tatcaagtgc tgttcggcgt tcaaacaaat taaactgttg
    12661 gaaaaccata gacaacttac ggcgtagggc aaggatttct tcttgagtga ttttagaaaa
    12721 atcaactgaa aaaccatcaa tctgaataga gccactgtca ggtgtttcaa gataattgag
    12781 actgcgaaga aaggttgatt ttccagctcc tgaagaacca atcaaggcta caacttcccc
    12841 tttttgaata tccaagtcca gatgatccaa gacagtctgt cctgaaaagg atttgcttaa
    12901 attcgaaatc ttaatcatta acgaaggtct cctttcacat ctgtttgcac tgtatcaggt
    12961 gcagaaatag ccatttttct ctcgatgaaa cgaccgagac tttcaattcc gatattgact
    13021 acccaataaa caagggcaac ggagatgaag cgttcaaaat agcgataatc agctccacct
    13081 agaatctgag cttgggcaaa gacttccaca acacccgcac taaaagctag agatgttccc
    13141 ttggtcaaac cgatgaggga attaatcaag gttggagtag ctaccaccgc tgcattagga
    13201 ataatcactc gtcgataaac ttgcgctcgg gtcataccca gactgcgtgc cgcctcaatc
    13261 tcaccaggat taactgagag aatggctgca cgaatggttt cactagcata agctgcctca
    13321 ttaaaggcaa aggcgacaat cgcaaaagct gcagctggaa tcgcattgat attgagacca
    13381 gttccccatt gctgattgag ggctttcaaa gccaaaggga ttccgtagta ggtcaacatg
    13441 agttgcacca aaatcggtgt cccttttaag aaactaacaa agaaggcctg caagggatat
    13501 aaaatcttga cacgattgat cttcacaatg gcaaaaagaa gcgccaaaac caagccaaaa
    13561 agggcaccac caattgtcaa cataattgtt gttggaagtt gttggacaat tctagggatt
    13621 ccatcaaaga ccgaacgtag gctaaacagc ttgccattcg gaatcaattg catcaagttt
    13681 tggtaccaat ctgatgctaa aatcgttgta acattcataa aaacatcctc ttctgataat
    13741 gattcattct accatgcttc tgccgtcaat gaaattattt gctacggtca gatacagact
    13801 ttgtctacct actagtttat catactttga aacagggaag ttatatattt tatctatcaa
    13861 agagatagat aaaaactatt tcagtcccag ttcttcataa gattttcgat aaccgatttg
    13921 cttaacggtt ccattttcta ctaaaatggg ccgttttaac aacataccgt cacttgctag
    13981 caactcagcc gcttcttggt ttgacaaact tcctacctta tcttttagcc ctaattcacg
    14041 gtatttgata ccactggtgt tgaaaaattg cttcaattca aatcctgagg tttctagcca
    14101 attcaaaatg acttcttggc taggtgtttc ttccacgata tggacggctt tatagtccac
    14161 acctaattga tttaattctt gttttgcttt tttacaagtt gaacatttgg ggtattcgat
    14221 aaattctaac atgtgcttct ccttctattg cttctatctt taaaatctac tccttcatgc
    14281 tccaagagcc aagctttctt ttccactcct gcagcataac ctgtcagacg cttgcctgct
    14341 cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca
    14401 attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga
    14461 ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc
    14521 gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca
    14581 ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc
    14641 ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca
    14701 agtgatagaa taccaattgg tgaggagtag agtattttta catacttctt ttgcattatt
    14761 tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa
    14821 aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa
    14881 aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc
    14941 cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt
    15001 gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat
    15061 aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga
    15121 taataacatc tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac
    15181 attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac
    15241 gaatttccat cttttttcct catttctgac tagtttctcc catcatagca taatttaagt
    15301 atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca
    15361 aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa
    15421 attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc
    15481 cctatctctc ctaataaaga caagggccta acagcatcta tggtcaacaa ttatgtgaaa
    15541 aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg
    15601 attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat
    15661 actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac
    15721 caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat
    15781 catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc
    15841 ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg
    15901 tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac
    15961 acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc
    16021 tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa
    16081 tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga
    16141 ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct
    16201 ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt
    16261 acctgattat gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac
    16321 ccgttttctg gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt
    16381 atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta actgcgtccg
    16441 tacttcaata catcgctatt gtttattaca tgtaaaactc tcagtaggca gagcctgctt
    16501 agagttttac aaacgaattt cccaaagagg aagcaatatg aaagcagtca ttgcttgtgt
    16561 tcataaaatt ctcagaatca tttacaaact actctccacc aagtagactt atcaaaaaga
    16621 aaaggcgcta ggactgaaga aacagttcta acgcccaaat taaaaaaatt tcaactacag
    16681 tatagcacag gaaatgattt tttgcgcttt tttactgttt tttcaaataa aaaaagacaa
    16741 agttttatcc ttgtctttta gttttagtat tgctttggtt tcaatgtcaa taagtgtgtt
    16801 ctt
//
LOCUS       DAVLHM010000045        16544 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLHM010000045 DAVLHM010000000
VERSION     DAVLHM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.045"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1059
                     /gene="lytB"
                     /locus_tag="VXE45_001710"
     CDS             <1..1059
                     /gene="lytB"
                     /locus_tag="VXE45_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0789712.1"
                     /translation="YYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAW
                     YYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSY
                     ISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYH
                     YVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDK
                     VFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGI
                     TAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWG
                     EKIASVMMKINEKLGGKD"
     gene            complement(1120..2775)
                     /gene="pavA"
                     /locus_tag="VXE45_001711"
     CDS             complement(1120..2775)
                     /gene="pavA"
                     /locus_tag="VXE45_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0789713.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2880..3377
                     /gene="ybeY"
                     /locus_tag="VXE45_001712"
     CDS             2880..3377
                     /gene="ybeY"
                     /locus_tag="VXE45_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0789714.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3358..3753
                     /locus_tag="VXE45_001713"
     CDS             3358..3753
                     /locus_tag="VXE45_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0789715.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3770..4669
                     /gene="era"
                     /locus_tag="VXE45_001714"
     CDS             3770..4669
                     /gene="era"
                     /locus_tag="VXE45_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0789716.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4718..5542
                     /gene="mutM"
                     /locus_tag="VXE45_001715"
     CDS             4718..5542
                     /gene="mutM"
                     /locus_tag="VXE45_001715"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0789717.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5542..6147
                     /locus_tag="VXE45_001716"
     CDS             5542..6147
                     /locus_tag="VXE45_001716"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0789718.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6134..7333
                     /locus_tag="VXE45_001717"
     CDS             6134..7333
                     /locus_tag="VXE45_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0789719.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7333..7482
                     /gene="rpmG"
                     /locus_tag="VXE45_001718"
     CDS             7333..7482
                     /gene="rpmG"
                     /locus_tag="VXE45_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0789720.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7522..7755
                     /gene="secG"
                     /locus_tag="VXE45_001719"
     CDS             7522..7755
                     /gene="secG"
                     /locus_tag="VXE45_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0789721.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KVRGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7857..10211
                     /gene="rnr"
                     /locus_tag="VXE45_001720"
     CDS             7857..10211
                     /gene="rnr"
                     /locus_tag="VXE45_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0789722.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAANYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10174..10641
                     /gene="smpB"
                     /locus_tag="VXE45_001721"
     CDS             10174..10641
                     /gene="smpB"
                     /locus_tag="VXE45_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0789723.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10657..11517
                     /gene="tehB"
                     /locus_tag="VXE45_001722"
     CDS             10657..11517
                     /gene="tehB"
                     /locus_tag="VXE45_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0789724.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11590..12543
                     /gene="coiA"
                     /locus_tag="VXE45_001723"
     CDS             11590..12543
                     /gene="coiA"
                     /locus_tag="VXE45_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0789725.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12562..14364
                     /gene="pepF"
                     /locus_tag="VXE45_001724"
     CDS             12562..14364
                     /gene="pepF"
                     /locus_tag="VXE45_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0789726.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14366..15079
                     /locus_tag="VXE45_001725"
     CDS             14366..15079
                     /locus_tag="VXE45_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0789727.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15146..16087
                     /gene="prsA"
                     /locus_tag="VXE45_001726"
     CDS             15146..16087
                     /gene="prsA"
                     /locus_tag="VXE45_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0789728.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFKKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16204..>16544)
                     /locus_tag="VXE45_001727"
     CDS             complement(16204..>16544)
                     /locus_tag="VXE45_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0789729.1"
                     /translation="LEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLS
                     PVQYRTKSFR"
BASE COUNT         4972 a         3082 c         3712 g         4778 t
ORIGIN      
        1 tactacttca aatccggtgg ttacatgaca gccaatgaat ggatttggga taaggaatct
       61 tggttttacc tcaagtctga tggcaaaatg gctgaaaaag aatgggtcta cgattctcat
      121 agtcaagcct ggtactactt caaatctggt ggttacatgg cgaaaaatga gacagtagat
      181 ggttatcagc ttggaagcga tggtaaatgg cttggaggaa aagctacaaa tgaaaatgct
      241 gcttactatc aagtagtgcc tgttacagcc aatgtttatg attcagatgg tgaaaagctt
      301 tcctatatat cgcaaggtag tgtcgtatgg ctagataagg atagaaaaag tgatgacaag
      361 cgcttggcta ttactatttc tggtttgtca ggctatatga aaacagaaga tttacaagcg
      421 ctagatgcta gtaaggactt tatcccttat tatgagagtg atggccaccg tttttatcac
      481 tatgtggctc agaatgctag tatcccagta gcttctcatc tttctgatat ggaagtaggc
      541 aagaaatatt attcggcaga tggcctgcat tttgatggtt ttaagcttga gaatcccttc
      601 cttttcaaag atttaacaga ggctacaaac tacagtgctg aagaattgga taaggtattt
      661 agtttgctaa acattaacaa tagccttttg gagaacaagg gcgctacttt taaggaagcc
      721 gaagaacatt accatatcaa tgctctttat ctccttgccc atagtgccct agaaagtaac
      781 tggggaagaa gtaaaattgc caaagataag aataatttct ttggcattac agcctatgat
      841 acgacccctt acctttctgc taagacattt gatgatgtgg ataagggaat tttaggtgca
      901 accaagtgga ttaaggaaaa ttatatcgat aggggaagaa ctttccttgg aaacaaggct
      961 tctggtatga atgtggaata tgcttcagac ccttattggg gcgaaaaaat tgctagtgtg
     1021 atgatgaaaa tcaatgagaa gctaggtggc aaagattagt actataagtg aatatgattt
     1081 gagtgaatag taagttaaaa atcctgattt caagtaaaat caggattttt tcatggatgc
     1141 aatttttttg gagtctggtg tgacgcggag ggtcttttgt cctgtgtaag tgacaaagcc
     1201 gggttttcca ccagttggtt tattgagttt tttgacttca atcatatcta cctgcaccag
     1261 attcgacagg cgcccttgag agaagtaggc agctaactct gctgcgtctg tcttgactgc
     1321 atcagatggg tcaagatttc ctgagatgac aacatggctt ccaggaatgt ccttagcatg
     1381 gaaccaaagt tcctccttgc gggccatttt aaaggtcaat tcctcatttt gaagattgtt
     1441 tcgtccgaca tagatgatgg ttttgccatc gcttgctaga tattgttcta gttttttgcg
     1501 tttctggatt ttctcccgtt gtcttctgcg gataaaacct gtttgaatca attcttcacg
     1561 gatttcagcg atttcttcca gtccagcttg gttgaggacg gtttctacac tttccagata
     1621 gagaatagtg gctttggttt cttcaatcaa atcagtcaag tatttgacag cttctttgag
     1681 tttctgatac cgtttaaaat agcgttgggc attctggttg ggagtcagag ccttatcaag
     1741 cgcaatcatg ataggttggt tggtatagta gttgtctagg ataacctggt cttggtcgtt
     1801 aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt tgacgaaatt cttcagcgtt
     1861 gtctgtcgcc agtaactctt tttcctgttt tttgagtttg tgtcggtttt tctgaagttc
     1921 attttcaaca cgacgaatca gttcactggc ctgctgtttg acgcggtcgc gctcagcctt
     1981 atccttatag taggtgtcca acaaatcaga aagatttgca agaggctctc ccacctgatt
     2041 tgcaaaagga actggactga aggaagtctc agtcaagcat ggcttggttt cttgattgaa
     2101 aaaatttcgg aaagcggaaa gtttttcact aaccagtatc ctttccaatt catttgccgt
     2161 atcgcgtccc agaccttgaa agaggctttg aagatttttt gctgttagtt cttgggtttg
     2221 caggatttca aagagctttt catccttgat agtaaaagga ttgagagatt ttgtacttgg
     2281 cggagcgata taggtcgatc ctggaagtaa ggtgcggtag ctattttgtg aaaagccgac
     2341 gtgtttgata acttcgagga ttttatgact gcttttatcg accagtagaa tattactgtg
     2401 tttccccata atttcgataa tcaaggtagc ctggatatgg tctccaatct cgtttttatt
     2461 ggaaactgta atttccacaa tacggtcatt ttccacttgc tcaatcgact caatcagggc
     2521 cccctgcaaa tactttctca aaaccatgat aaaggtagaa ggttgggctg gattttcaaa
     2581 agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg gcagaaagga gcaggcgatg
     2641 gctttggcga ttgctgcgga tttgcaagac caactcttgt tcaaaaggct gattgatttt
     2701 ctggatgcga ccattcacta attcgcttcg caattcctca actatgtggt gtaaaaaaaa
     2761 tccgtcaaat gacatcgttc tctccttgtg attgtattcc atagtattat atcaaaaagg
     2821 tagaataaaa tcatggaaat gtggtataat aaagccaagt aaagagaaac gagaagcaca
     2881 tgtatattga aatggtagat gaaactggtc aagtttcaaa agaaatgttg caacaaaccc
     2941 aagaaatttt ggaatttgca gcccaaaaat taggaaaaga agacaaggag atggcagtca
     3001 cttttgtgac caatgagcgt agtcatgaac ttaatctggg gtaccgtgac accgaccgtc
     3061 cgacagatgt catcagcctt gagtataaac cagaattgga aattgccttt gacgaagagg
     3121 atttgcttga aaatccagaa ttggcagaga tgatgtctga gtttgatgcc tatattgggg
     3181 aattgttcat ctctatcgat aaggctcatg agcaggccga agaatatggt cacagctttg
     3241 agcgtgagat gggcttcttg gcagtacacg gctttttaca tattaacggc tatgatcact
     3301 atactccgga agaagaagcg gagatgttcg gtttacaaga agaaattttg acagcctatg
     3361 gactcacaag acaataaacg aaaatggaaa aatcgtgacc tgatatccag tttagaattt
     3421 gccatcacag ggatttttac tgctatcaag gaagaacgca atatgcgaaa acatgcagtg
     3481 acggctctag tggtcatcct tgcaggtttt ggttttcagg tgtcacgaat cgaatggctc
     3541 tttctcctat tgagcatttt cttggtggta gcctttgaaa ttatcaattc tgctatcgaa
     3601 aatgtggtgg atttggccag tcactatcac ttttccatgc tggctaaaaa tgccaaggat
     3661 atggcggctg gcgcggtatt agtggtttct ctttttgcag ccttaacagg cgcattgatt
     3721 tttctcccac gaatctggga tttattattt taaacagtaa gaggaaatta tgacttttaa
     3781 atcaggcttt gtagccattt taggacgtcc caatgttggg aagtcaacct ttttaaatca
     3841 cgttatgggg caaaagattg ccatcatgag tgacaaggcg cagacaacgc gcaataaaat
     3901 catgggaatt tacacgactg ataaggagca aattgtcttt atcgacacac cagggattca
     3961 caaacctaaa acagctctcg gagatttcat ggttgagtct gcctacagta cccttcgcga
     4021 agtggacact gttcttttca tggtgcctgc tgatgaagcg cgtggtaagg gggacgatat
     4081 gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt ttggtggtga ataaaatcga
     4141 taaggtccat ccagaccagc tcttgtctca gattgatgac ttccgtaatc aaatggactt
     4201 taaggaaatt gttccaatct cagcccttca gggaaataac gtgtctcgtc tagtggatat
     4261 tttgagtgaa aatctggatg aaggttttca atatttcccg tctgatcaaa tcacagacca
     4321 tccagaacgt ttcttagttt cagaaatggt tcgcgagaaa gtcttgcacc taactcgtga
     4381 agagattccg cattctgtag cagtagttgt tgactctatg aaacgggacg aagagacaga
     4441 caaggttcac atccgtgcaa ccatcatggt cgagcgcgat agccaaaaag ggattatcat
     4501 cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg gcccgtcgtg atatcgaact
     4561 catgctagga gacaaggtct tcctagaaac ctgggtcaag gtcaagaaaa actggcgcga
     4621 taaaaagcta gatttggctg actttggcta taatgaaaga gaatactaag tagaggtggg
     4681 ctcatgcctg cttcttgttt ttacagaagg aggacttatg cctgaattac ctgaggttga
     4741 aaccgtttgt cgttgcttag aaaaattgat tataggaaag aagatttcga gtatagaaat
     4801 tcgctacccc aagatgatta agacggattt ggaagagttt caaagggaat tgcctagtca
     4861 gattatcgag tcaatgggac gtcgtggaaa atatttgctt ttttatctga cagacaaggt
     4921 tttgatttcc catttgcgga tggagggcaa gtatttttac tatccagacc aaggacctga
     4981 acgcaagcat gcccatgttt tctttcattt tgaagatggt ggcacgcttg tttatgagga
     5041 tgttcgcaag tttggaacca tggaactctt ggtgcctgac cttttagacg cctactttat
     5101 ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt gatttacagg tctttcaatc
     5161 tgcccttgcc aagtccaaaa agcctatcaa atcccatctc ctagaccaga ccttggtagc
     5221 tggacttggc aatatctatg tggatgaggt tctctggcga gctcaggttc atccagctag
     5281 atcttcccag actttgacag cagaagaagc gacagctatt catgaccaaa ccattgctgt
     5341 tttgagccag gctgttgaaa aaggcggttc caccattcgg acctatacca atgcctttgg
     5401 ggaagatgga agcatgcagg attttcatca ggtctatgat aagactggtc aaggatgtgt
     5461 acgctgtggt accatcattg agaaaattca actaggtgga cgtggaaccc acttttgtcc
     5521 aaactgtcaa aggagggact gatgggaaaa atcatcggaa tcactggggg aattgcctct
     5581 ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct ttcaagtagt ggatgccgac
     5641 gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt ttgaggctct agtacagcac
     5701 ttttggcaag aaatcattct tgaaaacgga gaactcaatc gccctctcct agctagtctc
     5761 atcttttcaa atcctgatga acgagaatgg tctaagcaaa ttcaagggga gattatccgt
     5821 gaggaactgg ctactttgag agaacagttg gctcagacag aagagatttt cttcatggat
     5881 attcccctac tttttgagca ggactacagc gattggtttg ctgagacttg gttggtctat
     5941 gtggaccgag atgcccaagt agaacgctta atgaaaaggg accagttgtc caaagatgaa
     6001 gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa agaaagattt ggccagccag
     6061 gttcttgata ataatggcaa tcagaaccag cttcttaatc aagtgcatat ccttcttgag
     6121 ggaggtaggc aagatgacag agattaactg gaaggataat ctgcgcattg cctggtttgg
     6181 taattttctg acaggagcca gtatttcttt ggttgtacct tttatgccca tcttcgtgga
     6241 aaatctaggt gtagggagtg agcaagtcgc tttttatgca ggcttagcaa tttctgtctc
     6301 tgctatttcc gcggcgctct tttctcctat ttggggtatt cttgctgaca aatacggccg
     6361 aaaacccatg atgattcggg caggtcttgc tatgactatc actatgggag gcttggcctt
     6421 tgtcccaaat atctattggt taatctttct tcgtttacta aacggtgtat ttgcaggttt
     6481 tgttcctaat gcaacggcac tgatagccag tcaggttcca aaggagaaat caggctctgc
     6541 cttaggtact ttgtctacag gcgtagttgc aggtactcta actggtccct ttattggtgg
     6601 ctttatcgca gaattatttg gcattcgtac agttttctta ctggttggta gttttctatt
     6661 tttagctgct attttgacta tttgctttat caaggaagat tttcaaccag tagccaagga
     6721 aaaggctatt ccaacaaagg aattatttac ctcggttaaa tatccctatc ttttgctcaa
     6781 tctcttttta accagttttg tcatccaatt ttcagctcaa tcgattggcc ctattttggc
     6841 tctttatgta cgcgatttag ggcagacaga gaatcttctt tttgtctctg gtttgattgt
     6901 gtccagtatg ggcttttcca gcatgatgag tgcaggagtc atgggcaagc taggtgacaa
     6961 ggtgggcaat catcgtctct tggttgtcgc ccagttttat tcagtcatca tctatctcct
     7021 ctgtgccaat gcctctagcc cccttcaact aggactctat cgtttcctct ttggattggg
     7081 aaccggtgcc ttgattcccg gggttaatgc cctactcagc aaaatgactc ccaaagccgg
     7141 catttcgagg gtctttgcct tcaatcaggt attcttttat ctgggaggtg ttgttggtcc
     7201 catggcaggt tctgcagtag caggtcaatt tggctaccat gctgtctttt atgcgacgag
     7261 cctttgtgtt gcctttagtt gtctctttaa cctgattcaa tttcgaacat tattaaaagt
     7321 aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct cctcttgtgg cagtatcaat
     7381 tacctaacca gtaaaaattc aaaaacccat ccagacaaga ttgaggtttt aaagtattgt
     7441 cccaaggaaa gaaaagtaac cctacatctt gaatctaagt agattttatg gtaaaataat
     7501 agggatttta aggagtttga tatgtataac ctattattaa ccattttatt agtattatct
     7561 gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa accaatccag caatgtattt
     7621 gatgccagtt caggtgattt gtttgaacgt agtaaagttc gcggttttga agctgtaatg
     7681 cagcgtttga cagggatttt agtctttttc tggctagcca ttgccttagc attgacggta
     7741 ttatcaagta gataagaaaa taatgggcag gactaggtct ttgcctcttt ttatttttaa
     7801 aggatgtttg agaaggtttt acagtaaaag aaaattaaaa aatctagaaa gaaaatatga
     7861 aagatagaat aaaagaatat ttacaagaca agggaaaggt gactgttaat gatttggctc
     7921 aggctttggg aaaagacagt tccaaggatt ttcgtgagtt gattaaaacc ttgtccttaa
     7981 tggaaagaaa gcaccaaatt cgttttgaag aagatggtag tctgacatta gaaattaaga
     8041 aaaaacatga gattaccctc aaggggattt ttcatgccca taaaaatggc tttggctttg
     8101 ttagtctgga aggcgaggag gacgaccttt ttgtagggaa aaatgatgtc aactatgcta
     8161 ttgatggtga taccgtcgag gtagtgatta agaaagtcgc tgaccgcaat aagggaacag
     8221 cagcagaagc caaaattatt gatatcctag aacacagttt gacaacagtt gtcgggcaaa
     8281 tcgttctgga tcaggaaaaa cctaagtatg ctggctatat tcgttcaaaa aatcagaaaa
     8341 tcagtcaacc gatttatgtt aagaaaccag ccctaaaatt agaaggaaca gaagttctca
     8401 aagtctttat cgataaatac ccaagcaaga aacatgattt ctttgtcgcg agtgttctcg
     8461 atgtagtggg acactcaacg gatgtcggaa ttgatgttct tgaggtcttg gaatcaatgg
     8521 acattgtatc cgagtttcca gaagctgttg ttaaggaagc agaaagtgtg cctgatgctc
     8581 cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga tgaaattacc tttaccattg
     8641 acggtgcgga tgccaaggac ttggacgatg cagtgcatat caaggctctg aaaaatggca
     8701 atctggagct tggggttcac atcgcagatg tttcttatta tgtgaccgag gggtctgccc
     8761 ttgacaagga agcccttaac cgtgcgactt ctgtttacgt gacagaccga gtggtgccaa
     8821 tgcttccaga acgactatca aatggcatct gctctctcaa tccccaagtt gaccgcctga
     8881 cccagtctgc tattatggag attgataaac atggtcgtgt ggtcaactat accattacac
     8941 aaacagttat caagaccagt tttcgtatga cctatagcga tgtcaatgat atcctagctg
     9001 gcgatgaaga aaagagaaaa gaatatcata aaattgtatc aagtatcgaa ctcatggcca
     9061 agcttcatga aactttagaa aacatgcgtg tgaaacgtgg agctctcaat tttgatacca
     9121 atgaagcgaa gattttagtg gataaacaag gtaagcctgt tgatatcgtt cttcggcagc
     9181 gtggtattgc cgagcggatg attgagtctt ttatgttgat ggctaatgaa acagttgccg
     9241 aacatttcag caagttggat ttgcctttta tctatcgaat tcacgaggag cctaaggctg
     9301 aaaaggttca gaagtttatt gattatgctt cgagttttgg cttgcgcatt tatggaactg
     9361 ccagtgagat tagtcaggag gcacttcaag acatcatgcg tgctgttgag ggagaacctt
     9421 atgcagatgt attgtccatg atgcttcttc gctctatgca gcaggctcgt tattcggagc
     9481 acaatcacgg ccactatgga ctagctgcta actattatac tcactttacc agtccaattc
     9541 gtcgttatcc agaccttctt gttcaccgta tgattcggga ttacggccgt tctaaggaaa
     9601 tagcagagca ttttgaacaa gtgattccag agattgcgac ccagtcttcc aaccgtgaac
     9661 gtcgtgccat agaagctgag cgtgaagtcg aagccatgaa aaaggctgag tatatggaag
     9721 aatacgtggg tgaagagtat gatgcagttg tatcaagtat tgtcaaattc ggtctctttg
     9781 tcgaattgcc aaacacagtt gaaggcttga ttcacatcac taatctacct gaattttatc
     9841 atttcaatga gcgtgatttg actcttcgtg gagaaaaatc aggtatcact ttccgagtgg
     9901 gtcagcagat ccgtatccgt gttgaaagag cggataaaat gactggagag attgattttt
     9961 cattcgtacc tagtgagttt gatgtgattg aaaaaggctt gaaacagtct agtcatagtg
    10021 gcagagggcg tggttcaaat cgtcgttcgg ataagaagga agacaagaga aaatcaggac
    10081 gctcaaatga taagcgtaag cattcacaaa aagacaagaa gaaaaaagga aagaaacctt
    10141 tttacaagga agtagctaag aaaggagcca agcatggcaa agggcgaggg aaaggtcgtc
    10201 gcacaaaata aaaaggcacg ccacgactat acaatcgtag atacgctaga ggcagggatg
    10261 gtcctgactg gaactgaaat caagagtgta cgagctgctc gaattaatct caaggatggc
    10321 tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg ttcatatcgc gccttacgaa
    10381 gagggcaata tctggaacca ggaaccagaa cgtcgtcgta aactcctgct ccataaaaag
    10441 caaattcaaa aattggaaca agagaccaaa gggacaggaa tgaccttagt tccccttaag
    10501 gtctatataa aagatggcta cgctaagctt cttttaggac ttgccaaagg gaagcatgac
    10561 tatgacaaac gggagtctat caaacgtcgt gagcaaaatc gagatatcgc gcgtgtgatg
    10621 aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg aaaaattagt tgcctataaa
    10681 cgcatgcctt tgtggaataa acaaacaatg cctgaagctg ttcagcaaaa gcacaataca
    10741 aaagttggga cttgggggaa aattactgtc ttgaagggag ctctcaagtt tattgaattg
    10801 acagaagaag gggaagttct agctgaacac ctctttgaag caggggcaga caatccaatg
    10861 gcccaacctc aagcctggca ccgagtggaa gctgccacag atgatgtgga atggtacttg
    10921 gaattttatt gtaaacctga ggattatttt gctaaaaaat acaataccaa tcctgttcat
    10981 tcagaggtcc tagaggccat gcagacagtg aaacaaggga aagctttgga tttgggttgt
    11041 ggtcaggggc gtaattctct ttttctagcc cagcaagatt ttgatgtgac ggctgtagat
    11101 caaaatggac tagctcttga aatcttgcaa agcattgtgg agcaggaaga tttggacatg
    11161 cctgttggcc tttacgatat caattcagct agcattgaac aagaatatga ttttatcgtt
    11221 tcaacagttg ttctcatgtt tctacaagcg gaccgcattc cagctattat tcaaaatatg
    11281 caggagaaaa ccagtgttgg tggttacaac cttatcgttt gtgccatgga cacggaggat
    11341 tatccttgct cggttaattt cccattcacc tttaaagaag gagaactggc agactattac
    11401 aaggattggg aattggttaa gtacaatgaa aatccaggcc atttgcaccg tcgcgatgag
    11461 aatggcaatc gtattcaact acgctttgcg accttactag ctaagaaaat caagtaaaca
    11521 cacatgaaga ttaggaattt tcctgatctt ttttcttttt tacgaatgat atagaaaagg
    11581 agggaattca tgtttgttgc gagagatgct aggggagaat tggtaaatgt gttagaggat
    11641 aaacttgaga agcaagcata cacctgccca gcttgtggag gccagctcca tttgcgtcaa
    11701 ggaccaagtg tacggacgca ttttgcccat aaatccttaa aagactgtga ttttttcttt
    11761 gaaaatgaaa gtccagaaca cctggccaat aaggaatccc tctatcactg gttgaaaaaa
    11821 gagacaaagg ttcaattaga gtacccgctt tcagaactta aacagattgc ggatgtattt
    11881 gtaaatggca atctagctct agaagttcag tgtagtccct tgcctcagaa agtccttaaa
    11941 gagcgaagtg agggatatcg tagtcagggt taccaagtac tgtggttgct gggtcaaaaa
    12001 ctgtggctca aggagcgttt gactcgtcta cagcaaggtt ttctttattt cagtcaaaac
    12061 atgggctttt atgtttggga attagacaag gaaaaacaag ttttaagact caaatacctg
    12121 atttaccagg atctccgcgg taaactccat tatcaaatca aggaattttc ctatggtcaa
    12181 ggtagtttat tggaaatatt gcgtcttccc tataagaaac aaaaaatatc tcattttaca
    12241 gtttctgagg acaaggacat ctgtcgctat atccggcaac aactttatta tcaaaatctc
    12301 ttttggatga aagaacaagc agaagcctat caaaagggag aaaatatcct gacttatgga
    12361 ctgaaagaat ggtatccaca aattcgacca atagtgggca aatttttcca gattgaacaa
    12421 gacttgacta gctattatca gcacttttat acctattacc aaaaaaatcc tcaaaatgat
    12481 tggcaaaagc tttatccacc agccttttat cagcaatatt tcttgaaaaa tatggtagaa
    12541 tagaaaggat ggaggaatct aatggtatta caaagaaatg aaataaatga aaaagataca
    12601 tgggatctat caacgatcta cccaactgac caggcttggg aagaagtctt aaaagattta
    12661 acagaacaat tggagacagt agcccagtat gaaggccatc tcttggatag tgcggataac
    12721 ctactagaaa tcactgaatt ttctcttgaa atggaacgcc agatggagaa gctttacgtt
    12781 tatgctcata tgaagaatga ccaggataca cgtgaagcta agtatcaaga gtactatgcc
    12841 aaggccatga cattctacag ccagttagac caagcctttt cattctatga gcctgaattt
    12901 atggagatta gcgaaaagca gtatgctgac tttttagaag ctcaaccaaa gctgcaggtt
    12961 tatcaacact attttgacaa gctcttgcaa ggcaaggatc acgttctctc acaacgtgaa
    13021 gaagaattat tggctggagc tggagaaatc tttggttcag caagtgaaac cttcgctatc
    13081 ttggacaatg cggatattgt gttcccttat gtcctagacg atgatggtaa agaagttcag
    13141 ctatctcatg ggatttacac acgtttgatg gagtctaaaa aacgtgaggt tcgccgtggt
    13201 gcctatcaag ctctttatgc gacttacgaa caattccaac acacctatgc caaaaccttg
    13261 caaaccaatg ttaaggtgca aaattaccgt gctaaagttc gtaactacaa gagtgctcgt
    13321 catgcagccc tcgcagcgaa ttttgttcca gaaagtgttt atgacaattt ggtagcagca
    13381 gttcgcaagc atttgccact cttacatcgc tatcttgagc ttcgttcaaa aatcttgggg
    13441 atttcagatc tcaagatgta cgatgtctac acaccgcttt catctgttga atacagtttt
    13501 acctaccaag aagccttgaa aaaagcagaa gatgctttgg cagtcttggg tgaggattac
    13561 ttgagccgtg ttaaacgtgc cttcagcgag cgttggattg atgtttacga aaatcaaggc
    13621 aagcgttcag gtgcctactc tggtggttct tacgatacca atgcctttat gcttctcaac
    13681 tggcaggaca atctggacaa tctctttact cttgttcatg aaacaggtca tagtatgcat
    13741 tcaagctata ctcgtgaaac tcagccttat gtttacggag attactctat ctttttggct
    13801 gagattgcct caactaccaa tgaaaatatc ttgacggaga aattattgga agaagtggaa
    13861 gacgacgcaa cacgctttgc tattctcaat aacttcctag atggtttccg tggaacagtt
    13921 ttccgccaaa ctcaatttgc tgagtttgaa cacgccattc accaagcaga tcaaaatggg
    13981 gaggtcttga caagcgattt cctaaataaa ctctacgcag acttgaacca agagtattat
    14041 ggtttgagta aggaagacaa tcctgaaatc caatacgagt gggctcgcat tccacacttc
    14101 tactataact actatgtata tcaatattca actggctttg cggccgcctc agccttggct
    14161 gaaaaaattg tccatggtag tcaagaagac cgtgaccgct atatcgacta cctcaaggca
    14221 ggtaagtcgg actatccact taatgtcatg agaaaagctg gtgttgatat ggagaaggaa
    14281 gactacctca acgatgcctt tgcagtcttt gaacgccgtt taaatgagtt tgaagccctt
    14341 gttgaaaaat taggattggc ataaaatggt tgaatcgtat agtaagaatg ctaaccataa
    14401 catgcgtcgt cctgtcgtca aagaagaaat tgtagacttg atgcgtcagc gtcaaaagca
    14461 ggtcacaggt ttcttgaaag aattggaaaa ctttgcccgc aaggaaaata ttcctattat
    14521 tccccatgaa acggttgctt atttccgttt tcttatggaa accatgcagc ctaaaaatat
    14581 tctggaaatt gggacggcta tcggtttttc agctctcttg atggctgaac atgcgccaaa
    14641 tgctaagatt acaactattg atcgtaatcc agaaatgatt ggttttgcca aggaaaattt
    14701 tgcccagttt gacagtcgca agcaaatcac tctcctagag ggagatgcgg tggatgtctt
    14761 atctacactg acagagtctt atgatttcgt ctttatggat tctgccaagt ctaaatacat
    14821 cgtctttctg ccagaaatcc tcaaacattt ggaagttggt ggtgtggttg tcttggatga
    14881 tatttttcaa ggtggtgatg ttgccaagga tattatggaa gtccgtcgtg gtcagcgaac
    14941 catttatcga ggccttcaaa aattatttga tgcaacctta gacaatccag aactcaccgc
    15001 aacattagtg cctttaggag atggtattct catgcttcgt aaaaatgtag cagatgttca
    15061 actgtctgaa agcgaatgat tttcagaaaa atttaagaaa aaatagtaaa atagatagag
    15121 taacacttat ctcaaaggag tagacatgaa gaaaaaatta ttggcaggtg ccatcacact
    15181 attatcagta gcaactttag cagcttgttc gaaagggtca gaaggggcag accttatcag
    15241 catgaaaggg gatgtcatca cagaacatca attttatgag caagtgaaaa acaacccttc
    15301 agcccaacaa gtcttgttaa atatgaccat ccaaaaagtt tttaaaaaac aatatggctc
    15361 agagcttgat gataaagagg ttgatgatac tattgccgaa gaaaaaaaac aatatggcga
    15421 aaactaccaa cgtgtcttgt cacaagcagg tatgactctt gaaacacgta aagctcaaat
    15481 tcgtacaagt aaattagttg agttggcagt taagaaggta gcagaagctg aattgacaga
    15541 tgaagcctat aagaaagcct ttgatgagta cactccagat gtaacggctc aaatcatccg
    15601 tcttaataat gaagataagg ccaaagaagt tctcgaaaaa gccaaggcag aaggtgctga
    15661 ttttgctcaa ttagccaaag ataattcaac tgatgaaaaa acaaaagaaa atggtggaga
    15721 aattaccttt gattctgctt caacagaagt acctgagcaa gtcaaaaaag ccgctttcgc
    15781 tttagatgtg gatggtgttt ctgatgtgat tacagcaact ggcacacaag cctacagtag
    15841 ccaatattac attgtaaaac tcactaagaa aacagaaaaa tcatctaata ttgatgacta
    15901 caaagaaaaa ttaaaaactg ttatcttgac tcaaaaacaa aatgattcaa catttgttca
    15961 aagcattatc ggaaaagaat tgcaagcagc caatatcaag gttaaggacc aagccttcca
    16021 aaatatcttt acccaatata tcggtggtgg agattcaagc tcaagcagta gtacatcaaa
    16081 cgaatagtcc aaatcaatga gtcagggaaa aaaactcgac ttcaggaaaa aatgaagcaa
    16141 acattcccac aataaaacgc atagtacaag gtttgtactg accccaaaag ttagacaatt
    16201 aatttatctg aaggatttag ttctgtattg cacagggcta agtcctttta gttttacctt
    16261 aattctctta ttgttgtaat aatcaatata gtctataatg gcttgttcca attgattaag
    16321 tgatttaaat gttttctcat agccataaaa catttcggat tttaaaatgc caaagaaaga
    16381 ttccatccta ccgttgtctt ggctgtttcc tttgcgtgac atagatgctt gaattccctt
    16441 actctctagg aagcgatgat aagaatcgtg ttggtattgc cagccttggt cactatggag
    16501 aatcgtattc tcgtagtgct tctctttgaa tgcctgttcc aaca
//
LOCUS       DAVLHM010000046        14623 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLHM010000046 DAVLHM010000000
VERSION     DAVLHM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.046"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(549..857)
                     /locus_tag="VXE45_001728"
     CDS             complement(549..857)
                     /locus_tag="VXE45_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0789730.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VXE45_001729"
     CDS             complement(854..1162)
                     /locus_tag="VXE45_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0789731.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VXE45_001730"
     CDS             complement(1167..2462)
                     /locus_tag="VXE45_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0789732.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VXE45_001731"
     CDS             complement(2480..3889)
                     /locus_tag="VXE45_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0789733.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VXE45_001732"
     CDS             4047..4775
                     /locus_tag="VXE45_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0789734.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VXE45_001733"
     CDS             5234..5428
                     /locus_tag="VXE45_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0789735.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5794..7104)
                     /locus_tag="VXE45_001734"
     CDS             complement(5794..7104)
                     /locus_tag="VXE45_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0789736.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALKLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7341..8213
                     /locus_tag="VXE45_001735"
     CDS             7341..8213
                     /locus_tag="VXE45_001735"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0789737.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            8344..9175
                     /locus_tag="VXE45_001736"
                     /pseudo
     CDS             8344..9175
                     /locus_tag="VXE45_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            9286..10212
                     /locus_tag="VXE45_001737"
     CDS             9286..10212
                     /locus_tag="VXE45_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0789738.1"
                     /translation="MDLSQTMPSYAQVVSLYDDTSISVSNNETDKVLAGSLYTDTNEQ
                     GLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQFQTKIVRVINDE
                     DDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQKNKKYTVLS
                     QQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIGVMKAVGYQ
                     NRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFELNLLSVLG
                     TLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            10389..11396
                     /gene="gap"
                     /locus_tag="VXE45_001738"
     CDS             10389..11396
                     /gene="gap"
                     /locus_tag="VXE45_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0789739.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(11463..12299)
                     /locus_tag="VXE45_001739"
     CDS             complement(11463..12299)
                     /locus_tag="VXE45_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0789740.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            12425..14620
                     /locus_tag="VXE45_001740"
     CDS             12425..14620
                     /locus_tag="VXE45_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0789741.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
BASE COUNT         4541 a         2589 c         2928 g         4565 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcca
      361 tttccagcaa ttttttagaa actacagtgg actattctag attcaacata ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tccgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcacttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ctgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacagggata tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttcgcc tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagagacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataggtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatctt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattggt ctataaattt tgagtttttc
     2461 atatgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatgggata ttaccatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc agccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcttcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt catctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagttctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaat agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt actgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaatatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgatgtta gaatagtaga ctgtgacttc
     5101 taacaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga acggtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactaca tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 tcttcatatt tttcatattc ttgaatccat cgataaagac tattgggatg aatttttaaa
     5641 gttgaactaa ttatttttac aggatgaggt ttacagcaga gagtttgaag gctttatcaa
     5701 aggtttttct tggcataatg acttttcctc gtttccactt aattttgtgt ctactttatt
     5761 ataccaagtc cacccttaag ttagataatg aatctaactt aaggaagcta gaaggatgag
     5821 aatccaggtg gtcaagagtc ccaaacttaa gctgataggg acacccagaa taatttgctt
     5881 tttgaaggca agaccgcgtt cctctatatt gggaagtgag agttgaatga gagaaccagc
     5941 tgatgaaaag ggtgagatat tagtagatag agcgccaata acggtggctg ttgtgagtaa
     6001 gtgaatatca atctgaggat tttgagcact gatgatagca atgatgggaa agagggctgg
     6061 agctacaacg gatagggtgg aactaaagag tgacatcact ccggctatca cacaaaagaa
     6121 cagaggtaac cagaaatgag gaatggttgt tgtcatgagg tgccctatca gtgtgactaa
     6181 acctgacttg accgctagag acattagtaa gctcatgccg cagagcatga taattgtagc
     6241 ccagggaacc ttagctaaaa tggcttcttg cttccctaat ttgagcttta aggcgaggca
     6301 gaccatgagt attgagacaa agccaatatc aaatgttttt tgataagtag ctatccaggc
     6361 gatgtttggg aaaatgagat gcaacaaggg aaaaagccaa accaaaacca tgctgctgat
     6421 catgagcaag gtggtttgtc tttgaacctt gctgaggagt ggtggttggt caatagtcaa
     6481 ggatgagttt gttcttccct tactatagtg actgtaacag gataataaaa gcaagacgat
     6541 gagtgggtag ataatgctga cgataaagat atgattgcca agtgaaaaag cttgctcttc
     6601 ccatcccatt tgcttaaaca ggccttgaaa gacaatgcct gagctactgg ttatcaaatt
     6661 agcccctcct gaagctcccc aattgacggc ttgagctcca atcaaagggt gtttgtccgc
     6721 tttttgacag agggtaatcg ctagaggaca gcaaacggcc atagtagtga aaaatccagc
     6781 acctaaagca gacaaaaggg ttgccatcag gtataaaatc atgtagaggg cgttagggtg
     6841 ggtgcgtgtg cggtagagaa tgtgttgagc caaaacatca agagtaccgt tagttgttgc
     6901 aacgttataa aagagagaga cgctaaaaat ggtaaaaaag agtgaggttg gccaaaaatg
     6961 aagaagttct ttggggctta atcccatgag agtggttgcg atgaggtaag aaaaagcaat
     7021 agccagcagg ccaatattga ttttggtgcg gtaaccaatt ccaatggcta gagcaatggc
     7081 gctaatcatt attaaatgaa tcattgaatt gtcctttcag ttagaatatg gaaataggtt
     7141 ggcaattttg gcgctcaaaa gaccacctgt ttcctattgg tacttgacta ttatacacaa
     7201 aaaaaataca attgtcttga caattgtatt gacacttgtt agaattaaaa atgaggtatt
     7261 caggcttgtg atttcctatg gaagttaata gtaattgcct ctagtgctta caagtgatat
     7321 taaaaataga ggacttagtg atgtcaatca tttcaactga tttaacccct tttcaaatag
     7381 atgatacatt gaaagcagcc ttgcgagaag atgttcattc cgaagattac agtaccaatg
     7441 ccatttttga tcatcatggc caagctaagg tgtcgctttt tgccaaggaa gctggtgttt
     7501 tagcggggct aaccgttttt caaagggttt ttaccctatt tgatgccgag gtgaccttcc
     7561 agaatcctca tcaatttaag gatggggatc gtttgactag tggcgatttg gttttagaaa
     7621 tcataggctc ggtgagaagt ctcttaacat gtgaacgcgt tgccttgaat tttttacaac
     7681 atttatcagg gattgcttcg atgacagctg cttatgtaga agccttaggc gatgattgca
     7741 ttaaggtatt tgatactcga aaaactactc ctaatttacg tctttttgag aaatatgccg
     7801 tgagagttgg cggtggctat aatcatcgct ttaatttatc agatgctatc atgctaaaag
     7861 acaatcacat tgcggcagta ggtagtgttc aaaaggcaat tgctcaagcg cgtgcctatg
     7921 ccccttttgt gaaaatggtc gaggtggaag tggaaagcct tgctgctgcc gaagaagctg
     7981 cggcggcggg tgctgatatt atcatgttgg ataatatgtc attggaacag attgaacagg
     8041 ccattaccct aattgcagga cgttctcgga ttgaatgttc tggaaatatt gatatgacca
     8101 ctattagccg ttttcgtggt ttagcgattg attacgtctc cagtggtagt ttaacccata
     8161 gtgctaagag tcttgatttt tccatgaagg ggttaaccta ccttgatgtc taagttgtaa
     8221 aataaactaa ctttttaaag gatgtctttc ctctagaacg agttttatgt cagatagttt
     8281 aaacgcctct tcaaatatag taaaatgaac caaaaatagt acacaatgtg gtataatctt
     8341 tttatggcat attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaacaggt
     8401 agtataacag aagcatcaca cgttttccaa atctcacgta ataccattta tggctggtta
     8461 aagctaaaag agaaaacagg agagctaaac caccaagtaa aaggaacaaa accaagaaag
     8521 gttgatagag atagacttaa aaactatctt actgacaatc cagacgctta tttgactgaa
     8581 atagcttctg aatttggctg tcatccaact accatccact atgcactcaa agctatgggc
     8641 tacactcgaa aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagccttatt
     8701 tcttaagaat tttaatagtt taaagcacct atcacctgtt tagattgatg aaacaggatt
     8761 tgatacttat ttttatcgag aatatggtcg ctctttaaaa ggtcagttaa gaagaagata
     8821 tcagaggatt tctttggttg caggtctaac aaatgaatgg tgagttaatc gctccaatga
     8881 cttacgaaga gacgatgacg agcgactttt ttgaagcatg gtttcagaag tttctcttac
     8941 caacattaac cacaccatcg gttattatta tggataatgc aagattccat agaatgggta
     9001 agttagaact cttgtgtgaa gagtttgggc ataaactttt acctcttcct ccctactcac
     9061 ctgagtacaa tctattgaga aaacatgggc tcatatcaaa aagcacctca aaaaggtatt
     9121 accaagttgc aatacctttt acgaggcttt tttatcctgc tcttgtttca attgactata
     9181 gttcacggat acagttggga aagaagctat taaatatttg gagagtcctt ttgggatgaa
     9241 catgtcaaat attactatag atgggcaaga aaagatgggc aagaaatgga tctgagtcaa
     9301 acgatgcctt cttatgctca agtagtgagt ctttatgatg atacaagtat ctctgttagt
     9361 aataatgaga cggacaaagt gttggctggc tccctctata ctgatacaaa tgaacaggga
     9421 ttaacgattc caagcagttt actaaaaaat tggaatgaac agacaggaaa aaatttgaca
     9481 gctaatgatc ttattggcaa atcagtctca gccagcattg tagaaagtgc tgccgaaact
     9541 agtaagattg ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga agatgacatg
     9601 gaggacagca acagtttcat gctgtctcat caaatggaaa cgattttgaa agaggctgga
     9661 tttacgaaag ctgtatctta ttttatcttg gaactcaaag atccatcaca gacaaaagta
     9721 gtaacagaag aattacagaa aaataagaag tatactgtgc tttctcaaca gagagttctt
     9781 gatattgtga ttacctttat tcgtgttatt cagggattat tgattgtgct ttcatcacaa
     9841 gctattgtgg tagcagcggt tatgattggt atcattattt acatcaatat catgcaacgt
     9901 tccaaggaaa taggtgtcat gaaagcagtt ggttatcaga atcgtggtgt caaaggaatt
     9961 tttatttacg aggctatctg gattgtaggc atcgccttgc tgctggcatt tttggttgca
    10021 caaggggtgg gaagtttggc gaatgcgatt gtaagtcact tttacccatc catcactaag
    10081 gtttttgaat taaatctttt atctgtttta ggaactctag ttttcgctct attacttggt
    10141 tatgtctcag cctacttccc ggcgcgtaag attagtaaaa tggatcctgt agaatcgtta
    10201 cgctatgaat aataagggat tccttgattt acagtcttaa aaagaaactc acatagaaaa
    10261 acaatggcca tacttgcaat tcaactcaaa tagttgtata ataggtttgt tgaaaggtga
    10321 tttgtagtga ttcaagttac tcttttcaca ataaaaattt catgattttc ataaggagga
    10381 aatcactaat ggtagttaaa gttggtatta acggtttcgg acgtatcggt cgtcttgctt
    10441 tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg catcaacgac cttacagatc
    10501 cagttatgct tgcacacttg ttgaaatacg acacaactca aggtcgtttc gacggtactg
    10561 ttgaagttaa agaaggtgga ttcgaagtta acggtaaatt cgttaaagtt tctgctgaac
    10621 gtgatccaga gcaaatcgac tgggctactg acggtgtaga aatcgttctt gaagctactg
    10681 gtttctttgc taagaaagaa gcagctgaaa aacaccttaa aggtggagct aaaaaagttg
    10741 ttatcactgc tcctggtgga aacgacgtta aaacagttgt attcaacact aaccacgacg
    10801 ttcttgacgg tactgaaaca gttatctcag gtgcttcatg tactacaaac tgcttggctc
    10861 caatggctaa agctcttcaa gataactttg gtgttgttga aggattgatg actactatcc
    10921 acgcttacac tggtgaccaa atgatccttg acggaccaca ccgtggtggt gaccttcgcc
    10981 gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac tggtgctgct aaagctatcg
    11041 gtcttgtaat cccagaattg aacggtaaac ttgacggatc tgcacaacgc gttccaactc
    11101 caactggatc agttactgaa ttggtagcag ttcttgaaaa gaacgttact gttgatgaag
    11161 tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg ttacacagaa gatccaatcg
    11221 tatcttcaga tatcgtaggt atgtcttacg gttcattgtt tgacgcaact caaactaaag
    11281 ttcttgacgt tgacggtaaa caattggtta aagttgtatc atggtacgac aacgaaatgt
    11341 catacactgc acaacttgtt cgtactcttg aatacttcgc aaaaattgct aaataattct
    11401 tgagttgata gaaagcaagg ctttgtggtc ttgcttttta tatggaaaaa tggatgacac
    11461 gatcatccat tcttttttaa ttctttttca aatgtatttg aaagggtagt gaaagttagc
    11521 ttctctaaag taagtgggtg ggtaaaggaa agtcggaagg catgaagcat aagccggctt
    11581 gtctttgatt tactattata gagagggtct cccaggatag gaagattatg atgcgaaagg
    11641 tgcacacgaa tctgatgggt tcgccctgtc tttagcttgc aatgagccaa ggaagtcttg
    11701 tttgagaatt gctttaatct gcttacatgc gtttcagcat attgcccatt ttttgcatca
    11761 actattcttt ttctacgatc atggcgatca cgtccaattt tgtctctgaa aacaagttct
    11821 tttctgttga tatttccatc aactagagcc caatattctc tagaaatctc ttttttctcc
    11881 aataagcgat tgagaatggg caggataaaa ggatttttgg caaagagaac taagccactg
    11941 gtttccatgt ccagacgatg aacgacatag caggtttggc caacataggt actgacatgg
    12001 ttaagaaggg caatttcgtt tggttgatta ccatgcgttt tcatcccctc tggtttgttt
    12061 acaataatca agtgttgatc ttgataaact tcctgcacta agtctgggtt gccccaaggg
    12121 atcgtctttt gggaataatc ttcctcgtca aaagtcaact ggcaaacatc tccaggattt
    12181 acgatttcct tccagtggac ttcttcttga tttatcaaaa tatgtttctt gattctcaaa
    12241 aaatgacgga tttttctagg gatgaggagt tgttcctcaa gtaattgctt tactgtcatt
    12301 tgaggtagag aggcgggtaa tgtaaatgtg aattgcatac agatattgta acaaaaaaag
    12361 ccctatttgg ataggaaata gctaaattct tgtcttccta tgatgaagat gataaaataa
    12421 acgcatgaaa ttagataaat tatttgagaa atttctttct ctttttaaaa aagaaacaag
    12481 tgaactagag gactctgatt ctactatctt acgtcgctct cgtagtgatc gaaaaaaatt
    12541 agcccaagta ggtccgattc gaaaattctg gcgtcgttat catctaacaa agattatcct
    12601 tatactaggt ttgagtgcag gcttgctagt tggaatctat ttgtttgctg tagccaagtc
    12661 gaccaatgtc aatgatttgc aaaatgcctt gaaaactcgg actcttattt ttgaccgtga
    12721 agaaaaagag gctggtgcct tgtctggtca aaagggaacc tatgttgagc tgactgacat
    12781 cagtaaaaac ttgcagaatg ctgttattgc gacagaagac cgttctttct ataaaaatga
    12841 cgggattaac tatggccgtt ttttcttggc tattgtcact gctggacgtt caggtggtgg
    12901 ctctaccatt acccaacagc tggctaaaaa cgcctattta tcgcaggatc aaactgttga
    12961 gagaaaagcg aaagaatttt tccttgcctt agaattaagc aaaaaatata gtaaggagca
    13021 aattctaacc atgtacctta acaacgctta ttttggaaat ggtgtgtggg gtgtagaaga
    13081 tgcgagtaag aaatactttg gagtttctgc atcagaagtg agtctggatc aagctgcgac
    13141 tctggcaggg atgctcaagg ggccggaact gtataatccc ttgaattccg tagaagattc
    13201 tactaatcgg cgcgatactg tcttgcagaa tatggttgca gcaggatata ttgataaaaa
    13261 ccaagaaacc gaagctgctg aagttgatat gacttcgcaa ttgcacgata agtatgaagg
    13321 aaaaatctca gattaccgtt acccctctta ttttgatgcg gtggttaatg aagctgtttc
    13381 caagtataat ctaacagagg aagagattgt caataatggc taccgcattt acacagagct
    13441 ggaccaaaac taccaagcaa atatgcagat tgtttatgaa aacacatcgc tatttccgag
    13501 ggcagaggat ggaacgtttg ctcaatcagg aagtgtagct ctcgaaccga aaacaggggg
    13561 agttcgtgga gttgtcggtc aagttgctga caatgataaa actggattcc ggaatttcaa
    13621 ctatgcaacc caatcaaagc gtagtcctgg ttctacaatt aagcctttag ttgtttatac
    13681 gccagcagtt gaagcaggct gggctttgaa taagcagttg gataaccata ccatgcagta
    13741 tgacagctat aaggttgata actatgcagg gatcaaaacg agtcgagaag ttcctatgta
    13801 tcaagccttg gcagaatcgc ttaatctacc tgctgttgcc actgttaatg atttgggtgt
    13861 cgataaggct tttgaggcag gcgaaaaatt cggactcaac atggaaaagg tcgaccgtgt
    13921 tcttggtgtc gccttgggaa gcggtgttga aaccaaccct cttcaaatgg ctcaagcata
    13981 cgctgccttt gcaaatgaag gtttaatgcc tgaagctcat tttattagta gaattgaaaa
    14041 tgctagtgga caagttattg cgagtcataa aaattcacaa aaacgggtga ttgataagtc
    14101 tgtagctgac aagatgacca gtatgatgtt ggggactttc accaacggta ccggtattag
    14161 ttcatcgcct gcagactata ttatggcagg gaaaactgga acaactgaag cagttttcaa
    14221 tccggagtac acaagtgacc agtgggtaat tggttatact ccggatgtag tgattagcca
    14281 ctggcttggc tttccgacca ctgatgaaaa tcactatcta gctggctcta cttcaaacgg
    14341 tgcagctcat gtctttagaa acattgccaa taccatttta ccttatacgc caggaagtac
    14401 ctttacggtt gaaaatgctt ataagcaaaa tggaattgca ccagccaata caaaaagaca
    14461 agtacaaacc aatgataata gccagacaga tgataatttg tctgatattc gagggcgtgc
    14521 gcaaagtcta gtagatgagg ctagccgggc tatctcagat gcgaagatta aggaaaaggc
    14581 tcaaacaata tgggattcga tagtcaatct atttcgctaa gat
//
LOCUS       DAVLHM010000047        14237 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLHM010000047 DAVLHM010000000
VERSION     DAVLHM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.047"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            83..880
                     /locus_tag="VXE45_001741"
     CDS             83..880
                     /locus_tag="VXE45_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0789742.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VXE45_001742"
     CDS             1028..1150
                     /locus_tag="VXE45_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEV0789743.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            1172..2287
                     /locus_tag="VXE45_001743"
     CDS             1172..2287
                     /locus_tag="VXE45_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0789744.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGSSCHNLSYIRDVGAATFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPNQIRLSIGLENVEDLIEDLRLALEKI"
     gene            2383..3657
                     /locus_tag="VXE45_001744"
     CDS             2383..3657
                     /locus_tag="VXE45_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0789745.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VXE45_001745"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VXE45_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0789746.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VXE45_001746"
     CDS             4786..5088
                     /locus_tag="VXE45_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0789747.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VXE45_001747"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VXE45_001747"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0789748.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VXE45_001748"
     CDS             5962..7302
                     /locus_tag="VXE45_001748"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0789749.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VXE45_001749"
     CDS             7280..7492
                     /locus_tag="VXE45_001749"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0789750.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VXE45_001750"
     CDS             7489..8364
                     /locus_tag="VXE45_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0789751.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VXE45_001751"
     CDS             8357..9172
                     /locus_tag="VXE45_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0789752.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VXE45_001752"
     CDS             9165..9596
                     /locus_tag="VXE45_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0789753.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VXE45_001753"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VXE45_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0789754.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VXE45_001754"
     CDS             11272..12000
                     /locus_tag="VXE45_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0789755.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VXE45_001755"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VXE45_001755"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0789756.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13983..>14237)
                     /locus_tag="VXE45_001756"
     CDS             complement(13983..>14237)
                     /locus_tag="VXE45_001756"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789757.1"
                     /translation="AGYSKHSFEVVDETDEVSSKHGFEVVDETDEVSSKHGFEVVDET
                     DEVSSKHGFEIVDETDEVSNHTYGKATLTWFEEIFEEYKN"
BASE COUNT         4205 a         2607 c         3376 g         4049 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatgatttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 attcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggat ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 gactccagct actgagtctc gtgcagtgcc gatttatcaa acaacatctt ttgtttttga
     1141 tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatattga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatattc gtgatgtggg tgcagcaacc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa actctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaacc aaattcgtct
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgacc
     3541 acatctgaaa accaactccg tttagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat taacttaaaa aaggaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgaagact
     3901 gaggatgcta gtggggaagt ggtcgcagaa acccctgttt tgtctctctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac gtacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctgat gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggaacctcaa gatgtcttta
     5521 tcgttgaggg tattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggtgt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttagagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgctttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttgggac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgtta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgtac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ccatgaatga catggaaagt gtcgaagagt
    10381 atgaccctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg cacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cattttagta
    10801 agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcgtcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatatttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagag cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga tctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaatcgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagtt ttgactacga attgtcagaa tatcgcccat ctaagctagt gaaaatggat
    13561 atccttctca acggagacaa ggtggatgcc ctcagcttta tcgttcataa ggactttgct
    13621 tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaggttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaatctcaa aaccatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc agtttcatct
    14161 acaacctcaa aaccatgttt tgagctgact tcgtcagttt catctacaac ctcaaaactg
    14221 tgttttgagt aacctgc
//
LOCUS       DAVLHM010000048        13899 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLHM010000048 DAVLHM010000000
VERSION     DAVLHM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.048"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..512
                     /locus_tag="VXE45_001757"
     CDS             <1..512
                     /locus_tag="VXE45_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0789758.1"
                     /translation="IGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSDHEWML
                     TDIKNFLTKHKAWVIDGNYSWCCYQERMQEADQIIFLNFSPLTCLFRTFKRYLKYRGK
                     VRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRELDQFL
                     DKKRKSYNS"
     gene            complement(535..1245)
                     /gene="deoD"
                     /locus_tag="VXE45_001758"
     CDS             complement(535..1245)
                     /gene="deoD"
                     /locus_tag="VXE45_001758"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0789759.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1903..2415)
                     /locus_tag="VXE45_001759"
     CDS             complement(1903..2415)
                     /locus_tag="VXE45_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0789760.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(2440..3420)
                     /locus_tag="VXE45_001760"
                     /pseudo
     CDS             complement(2440..3420)
                     /locus_tag="VXE45_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(3896..4705)
                     /locus_tag="VXE45_001761"
     CDS             complement(3896..4705)
                     /locus_tag="VXE45_001761"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0789761.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(4705..5262)
                     /locus_tag="VXE45_001762"
                     /pseudo
     CDS             complement(4705..5262)
                     /locus_tag="VXE45_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(5264..6475)
                     /locus_tag="VXE45_001763"
     CDS             complement(5264..6475)
                     /locus_tag="VXE45_001763"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0789762.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(6489..7172)
                     /gene="rpiA"
                     /locus_tag="VXE45_001764"
     CDS             complement(6489..7172)
                     /gene="rpiA"
                     /locus_tag="VXE45_001764"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0789763.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(7454..8326)
                     /locus_tag="VXE45_001765"
     CDS             complement(7454..8326)
                     /locus_tag="VXE45_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0789764.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(8468..9325)
                     /locus_tag="VXE45_001766"
     CDS             complement(8468..9325)
                     /locus_tag="VXE45_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0789765.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(9479..10213)
                     /locus_tag="VXE45_001767"
     CDS             complement(9479..10213)
                     /locus_tag="VXE45_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0789766.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESRKVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(10213..10896)
                     /locus_tag="VXE45_001768"
     CDS             complement(10213..10896)
                     /locus_tag="VXE45_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0789767.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            11086..11316
                     /locus_tag="VXE45_001769"
     CDS             11086..11316
                     /locus_tag="VXE45_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0789768.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            11545..13803
                     /locus_tag="VXE45_001770"
     CDS             11545..13803
                     /locus_tag="VXE45_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0789769.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
BASE COUNT         4122 a         3137 c         2541 g         4099 t
ORIGIN      
        1 ttatcggata ttctggttct ggtaagtcaa ctctagcaga aaagttatct aactactact
       61 ccattccaaa actgcacatg gacacactcc aatttcaacc tggttggcaa gacagtgacc
      121 acgaatggat gttaaccgat ataaaaaact ttctcaccaa gcataaagct tgggtcatcg
      181 atggtaatta ttcttggtgc tgctaccaag aacgaatgca agaagctgac caaatcatct
      241 ttctcaattt ttcgccattg acctgtctct ttagaacctt taagcgttat cttaaatacc
      301 gtggaaaagt cagagaaagt atggcggcag attgccctga acgctttgac tgggagttta
      361 tcagatggat tctttgggat gggcgtagca aaactcaaaa agaaaattac caaaaacttt
      421 gccaagaata ttcacataaa gtcactattc ttcgaaatca gagagagcta gatcaatttc
      481 tggataagaa aaggaagtcc tacaattcat aaagggcttc ctttttggct ataattattc
      541 tgcaatcaag gtttccaaac caaccttcat catatcagtg aaggtatttt gacgttcttc
      601 tgcagttgtg tcttcgtctg gattgaccaa gctatcagag atggtcatga tagctagcgc
      661 atcaacatgg tattgggcag caagatagta aagagctgct gcttccattt ccacagcctt
      721 gactccccat ttaccaagct cgatattctt ttcaaagtaa tttgagtaaa agacatcaga
      781 tgacaaaacg ttcccaacgt gagtagtcat accaagtttt ttggcgatat ggtaggcttt
      841 atcaagcaaa tcaaagctag caatttgtgg aaaatcgtac tgtggccagt cattacgaac
      901 gatgtttgag ttggttgcag ccgcctgcgc caaaactaat tcacgaacat gaacctcttc
      961 attcaaagaa cctgcagttc ccacacgaat caatttcttc acaccgtagt ctacgattaa
     1021 ctcacgcgca taaatcgaaa tagatggcat tcccatccca gttcccatga cagatacaca
     1081 gtgacccttg taagtaccag tgtaaccaaa catgttacgc acttcgttaa aacaaacagc
     1141 atcatcaagg aaattctccg caataaactt agcacgaaga ggatccccag gaagaagaat
     1201 tttatcagca atttcaccct gctgagcagc aatatggata gacataattt atgatacaaa
     1261 gagcgagaag aaaacgactg aaaattagga acctgacgag aaatcctgat ttttcagtca
     1321 gattatctat tttccgagtt ttccgctcgt gttcaaatca aaacacacgc tctacctttc
     1381 tttattttat attttatatt gagaaagata ccaaacccat caaaaagcga agggaaaata
     1441 ggagttgggc gcagtgagcg atgctcgcta gaccaactat ctttttccca ctgcttttag
     1501 ggtggggtca attcctttct ttcttaattt tgatttagag gagagtcgcc cgtattcagt
     1561 tcagcgaata cagtttaccc atcctttcgt ttttattttt agaaaagttt tctactcgtg
     1621 ttcaaattag aacacgcgct ctacctttct gtttatactc ttcgaaaatc tcttcaaacc
     1681 acgtcaacgt cgccttggat tatatatgtg actgacttcg tcagtcttat ctacaacctc
     1741 aaagcagtgc tttgagcaac ctgcggctag tttcttagtt tgctctttga ttttcattga
     1801 gtattaattt tgttctttca cagagagcta cctgagttct attcaagctc aggtagtact
     1861 ttcttataaa ctagacaaac taactgtcat tgtaccatca gattacaaga catcatcgtc
     1921 actcaccttg gaattcaatg tcgtacccca atgggtaatt ttacggtggg gttgagctaa
     1981 aattggtctg ttttcataga ttgtttgcca tctattccat agtaggcccg tctttttctc
     2041 aatcttaact cgcagatttc tcatattttc tttgattggg aggttgagga caaaacctgc
     2101 agtctggttg cgaccgtttc cttcccaaga atgactacga acaacttggt ttccatcttt
     2161 atctactgta acttcttccc aagttatgga gtagcgggca atgtaagctc cactgtgttg
     2221 aattgtcaat gttttatctt tcacaggagt ctgactgatt ggttgaactg gcttagaaac
     2281 ttgtgtcgcc gtttcagcat tcgtagctat aaagcggaaa acttcaactt ctgcaagact
     2341 gagggcatta tagccttcta gcccaatccg aacatagcgc gcttttttat ggttaatcgt
     2401 aatttgtgct gacacatctt taggagatat tatacgtttt cactcaattt ctttaccaga
     2461 actgtctaaa agaatgacat caaagtttgc caatctatcc tgggcagtgt ctgttcggtt
     2521 gtaaatattg atttggcgaa tggtttcttc tttagccaaa tctacttgcc accaaggctt
     2581 agattggaag tttgtatgag tgacagaatt gtgaccatag ttaccatcga ctttgccatc
     2641 cacagctctt ctagcatctc ctccgaaagc tgtcgaactt tgagtaacct gttttcctaa
     2701 ggcaatattt tccattggtt cagcgcttgg ttgactagaa gattgaggta gagcctgttt
     2761 cttaaagaat cgcactttat ccaatttcgg atcacgataa ccatgtttat ccaaggtagc
     2821 ttgtttacca atattaaagt taggaatatc attcattgga ctttcaaaat agccacgaga
     2881 acggtgttta aagcgtgaat tacctgtaaa tgtaacaata tcacgattat tatgaatcaa
     2941 gggagtcaca acattgtcat tatcaaccac ataatgctta atttttccac taacagctaa
     3001 tttacgactt tccaaaccaa catctcagaa accattctta gcatcccaaa cagttctgga
     3061 agtaatcact ttaggagcac tgaaagttgt cactttcctc aatacatggt tataaaaatc
     3121 aggatatttt tggtaagctt caaccgctgc aatctgagct aggtaacatc caagagaatg
     3181 acctgtcata tacaacttag taatacttat atccttggct aattccccaa caaccttgcg
     3241 gatatcatcc gcttgagctg gctctattat ctctactttt gactcttccc ttttgttttc
     3301 aagaacttca cttgcttccg gaagcgtttg aggagctagt cttggctcct ctctaagagg
     3361 agtttctagt tttggagcat cattttctga ctctttcaat tcctccttag aatctagcac
     3421 acctattacc acttcagatg ttacatcttg ctttacttca ttggctgaaa ttccagctgg
     3481 agctagaaat caaagccgac tacaacagat acaactccga tacttaattt tttatgccaa
     3541 agcgcataat tcgttgacca attttcatta tttcttatct ttcttttcgt ttatttacaa
     3601 gcagactcaa gcgaaatctc attgtgctat atatgataag actgagaaat tcagaaagtc
     3661 aattcattct catctctcct tatcatacta gtctacttgg ctaggaagct aatgctagta
     3721 tcctagaatc ttgtctttca caatgctggc tatcagatca gacacaccta ttcttccgct
     3781 tctttcagtt ataagagcag gaagaagctc atagtattcc tctgtttctt ctttaatccg
     3841 gataggcagt caatcctgaa aaaacagagg cactccccct tttaaatctt ttttcttaca
     3901 attcagcaag aatcgcttta agcaagcctt tgaaatcacc tttaacacgt tcagtcactt
     3961 ctacaacttc ttcgtgattg agttcttctt ggaaaccggc cgcaaagtta gtgatacatg
     4021 aaattcccag aactttcaag ccagagtggg ccgccacgat aacttcagga accgtagaca
     4081 taccaactgc atctgctccc agtgtcttat aggaacgaat ttctgctggt gtttcataag
     4141 tcggaccagt aactccgata tagacacctt catcaagctt gatattaagt tttttagcca
     4201 cttcatgggc agtggcacgg tattctggtg tgtaggccct agacatatct gggaaacgtg
     4261 ggccaaagtc atccaagttt tcacccatca atggattttg ccccgtcatg ttgatatggt
     4321 ctgagatagc catcaaggta ccaggaccaa atccgatacc gccagctgca ttggttacaa
     4381 taacaccttc acatccaaga actttcatca cacgaactgg gaaagtcacc acttccagag
     4441 gattcccttc atagaaatgg aaacgccctt gaagagccaa gaccttgcga cctgccagtt
     4501 caccatatac caatttacca gcatgaccga ctactgttga acggccccag tttggaatct
     4561 cagcatagtc tactacaact ggattttcga tttcttctgc caattctcca agtcctgacc
     4621 caaggattag accgaactca ggggctgcaa ttcccttttc tttcaggaaa gtagcagttt
     4681 catggatttt gtttaaaaat gtcattatgt gtctccttta ttatttttta gcatttgacc
     4741 aattttgtca aaggttttag cattacgaat agtaatgtgg cggtagaaag gcaccttcag
     4801 caagtactta tgataggcag tcttagaata ggattcttca gaaaatttcc cccagaaaat
     4861 cccaagtttt ctaaaataaa gcacttcatc tttcagctct aaactttcaa ctgtcgcgat
     4921 gacttggtcc acatccaaac cctcagtgta aaagagaaaa tcttttcgtg ccaagtctct
     4981 gctccaccaa gctggtagat tttcaagttc cgcctcaaag tcctctagac tcagtaaaga
     5041 aaagctctga ataaatggat aatggactgc aaagaaagtc tctagctttt aaaccaattg
     5101 ggctttggaa tctatcgaag taaagaaaat attgccactg ttgatgtagc tctcaacctt
     5161 ttccagtccc aagtttgtca attcttgacg aagctccgcc ataacgacct tattcttact
     5221 accaacattg atacctctca ccagcaaagc atagcgcgtc atcttatacc aatttatcta
     5281 agaaactttc cccaatcata gcagtttcca caccaaagtt atcggcaaca gtcgctgaaa
     5341 tatctgcaaa atgtcctact ggaatgagac catttccttt aaaggcaggg ctatatgcca
     5401 acaatggaat atattcccga gtgtgatccg tccctgcata cgttgggtca tttccatggt
     5461 ccgcagtaat caagagaagg tcattctctc tcatagctgc gataatttca ggtaagcgtt
     5521 catcaaactc atgcaaacaa tcacggtaac cgtgagcatt acgacgatgg ccgtaaaggg
     5581 catcaaagtc aactaggttt gtgaatgaga atcctttttc aaactcagca agtcccatag
     5641 tcttcaatag tgtatcaatt ccatgactat ttgacttgtt gtgacccatg tcatggttga
     5701 taccagcacc gttaaagata tcgttgattt tacccacagc ataagtatcg ataccagcct
     5761 cattcaattt atccaaaaca gttggggaaa atggagatac agccaagtca cgacggtttg
     5821 ccgtacgagt gaagttacct ggttcaccta cataagggcg agcaatgatg cgaccaagaa
     5881 gggcaggacg ctcaagggta atcgaacgag cgtattcaca gatacggtac aattcatcca
     5941 aaggaataat gtcttcgtgg gcagcaatct gcaaaacagg gtcagctgaa gtatagataa
     6001 tcaactctcc agtttccatc tgacgtggtc caaaatcatc gataacagcc gttcctgaat
     6061 aaggtttgtt ggcttcacga ataaccttgc gtcctgagaa ttcttcgatt tttgtcagga
     6121 tttcttctgg gaatccgttc cagaaagtat cgaaaggctc agtaatgttg agtcccatga
     6181 tttcccagtg tccagtcata gtatccttac caagagatac ttcctctaat tttgttgcat
     6241 atccagttgg attgatttca gctgctacag tcttaagagg agtttcacga ggaatatttc
     6301 caagacctat tttagccatg tttgggacat tcaaaccaac tgtttttgaa atgtgtccca
     6361 gtgtgtcaga agctccatct ggaacccctg cattgacaaa gttattagca tctggtgctg
     6421 caccgattcc tacagaatcc agtaccacca aatgaatacg attaaattta gacatcttat
     6481 gcccccttct attttccttt ttttgaagtt gaaatctgaa ctccatctcg tccagcaacg
     6541 attaccttat ccaccatttg gttgaataaa ccatgctcca caacaccaac gacatggtcc
     6601 aattcttgtc caaaagcaat tggattttca atgacatcca aggcgaggtc aatgataaaa
     6661 ttctgcatat ccgtcacaaa acgttggccg tctttttcac ggaaacttgg tttgtagcca
     6721 gctcgttcaa aatgacgaaa gacctgctct gcaccatact gaaccacttc tactggcaat
     6781 ttaaaagcac ctagtttttc gaccagcttg ctttcatcca ccacccaaat gtattctttt
     6841 gatggtgttg cgaccacctt ttccatgaga agggcaccac caccgccttt gattccatta
     6901 aactgactat ccacttcatc cgcgccatca accgtcacat cgacaaagtc tacttggtca
     6961 atagacttga gcgggatatt aaggccttct gcctgtttag tggtcacact agaagttgtt
     7021 acagctgtaa tctgcaatcc ttcttccttg atacgacgac cgatttcttc gacaaaataa
     7081 taggcagtcg agcctgttcc aagtccaacg accattccat cgctcacgaa ctcagcagcc
     7141 ttgatacctg ccattttctt cagattttcc accgatttac ctccatcatt ctcagttctt
     7201 attttactat gaaaccgctt tttattcaag taaaaacatc aaatctacat ttttcatcaa
     7261 tctttcttta aaaatatgca ttttattttt accaaacgaa taaaaatgag tttatctttt
     7321 atgtatttga tttgttcatc tctttccagt tacaaaaaca aactcttaac tttgatacgt
     7381 ctagtttagc cttaaagcag gcgcatttca agaatcataa attaagagaa ggaagtagat
     7441 ttatctgtct attttaaaca agtttatctt tgcttaccct ctcttgttga caaataattt
     7501 tcattatttt gggaagatac ctgctgattt ccgtcggtaa gaccacataa ttttcctgag
     7561 atagttcttg ggctatggct gaatgaagat gggtcgctac tgccacacgc tcgtagagac
     7621 tggcctgtcg gaattggcct acaaatcctg cgatcatccc agccagagta tctcccattc
     7681 ccccagtcgc ctgataagga ccaccaacct gtaactggta ataatcagat tggccaactt
     7741 cccaaatacg agtagctggg cctttctcca ccaaaattgt tccttgaggg aaggaagtca
     7801 gaacactagc cgttgcatct tccttttgct tttcaatcgt aattccagat aatttttccc
     7861 attctttttg gtgaggagtt aggataagct ggcttgaggg aaatgacaaa cttgtcctag
     7921 caagaatggt caaggcacct ccgtctacaa tcaaaatctg attttggctt aaattaacaa
     7981 agacctgttt tactagattt tctccagaag catcgtctcg taaaccaggc cccaacaaga
     8041 caacttctgc cttctccaat tgctctttta acaattgctg gtcttgaaga gaaaaggcca
     8101 taggctcagg taaatggctg tgcagagccg ggatattttc cctgtccgtt ccaacggtca
     8161 ccaatcctgc accgcttttt acagctgcta aagcagccat gatgatggca cctccataag
     8221 gataagtacc accaagcagc agcagacgac cataatctcc tttatgactt gaacgagaac
     8281 gttcaataat aactttttct aataaggttt gattaatcac tttcatcctt ttttcctctc
     8341 acttttatta tacaataaaa aggagacgca gacctccttt tgtaatctta tatctaaaat
     8401 ttaatattca tttctgccat tttagatata gctatagaaa atacactcta ttaatcgaat
     8461 gtttctctta ttttctatcc aatgtccgaa gtgctgcttg ataagtttgc tccatcagca
     8521 tggtaatggt cataggaccg acacctccag ggactggcgt gatatagcta gcaagtggtg
     8581 caactgcctc ataatcaaca tctccacaga gcttcccatt ttcatctcgg ttcatcccaa
     8641 cgtcaatgac aaccgcacct ggtttgacaa agtcagcagt cacaaacttg gcgcggccga
     8701 ttgcgactac aagaatatct gctttagcag ccaccttggc aagattatga gttcgtgagt
     8761 gggtcaaggt tactgtcgca tttttagcca aaagaagctg agccataggt tttccaacga
     8821 tatttgaacg accgatgacg accgcatttt taccttccaa gtcaatccca tattcatgaa
     8881 acatttccat aattcctgca ggtgtcgagg gaatcatgac tggatgtcca gaccaaagac
     8941 gtcccatgtt taagggatgg aaaccatcca catccttttc tgggtcaatg gctaataaaa
     9001 ccgcctcttc atcgatatgt tttggtaatg gcaactggac caaaatccca tgccaagctg
     9061 gatcctgatt atatttagca atcaggtcta acaattcctc ttgagtaatg gtctctggaa
     9121 ctcgcactac ttcgctacgg gaaccagccg caagagctga cctctccttg ttgcgaacgt
     9181 agacttggct ggctggatta tccccaacca aaatcactac caaaccaggc actagagctg
     9241 tttcttcctt taattttgca gtcttttcag ccaactgccc ctgcaatttg gccgctaaag
     9301 ctttcccatc aataatctgt gtcatatcac ttctcttttc tttcaaatat cttccattat
     9361 accaaaaact gctagtgccc tctaacactt ctttcctagg ttatcctata gtttcaaact
     9421 ataagaaaaa gctctggttg aacttttcac taatcttgtc ttgaaatttt aaaatagatt
     9481 ataaaacctt actcaagaaa tctttagtcc gttgttcttg ggtttgttca aaaatctgct
     9541 caggtgtccc atcttcaaca accacaccgt ctgccataaa gataacacga tctgccacct
     9601 cacgggcaaa tcccatctca tgtgttacga taaccatagt catccctgac ttggcaaggt
     9661 cttgcataac agccaatacc tcacctacca tttcaggatc caaggctgaa gttggttcgt
     9721 caaagagcaa aacatctggt tccatagcca acccacgcgc gatggcaatc cgttgttgtt
     9781 gcccacccga cagactctgt ggataagcgt ctgccttatc tggcaaacca actttttcca
     9841 aaagctcttg ggctctcttc tcagcaactt tcctgctttc acctttagtc ttgataggtg
     9901 acaaggtaat attttccatc acagtcatat taggaaagag gttaaattgt tggaaaacca
     9961 tgcccatctt ctcacgcatg gcaaacaggt cattcttctt gtccgtaata tcgactccct
    10021 caaagataac cttccccttg gttgcttcct ccaacaaatt catagagcga agcaaggtag
    10081 atttcccact ccctgaagga ccgatgataa cgacaacttc tcctctttta atctcgaggt
    10141 tgatgccctt caatacttca ttctttccaa aagatttatg taaattttca atttttatca
    10201 aggtttctgt cattatttct tatctccttg tcccatatgt ttttcaaaag ctttcaaggc
    10261 tactgtcaga atagaggtca taatcaagta gtaaaatgct gcaaataaaa gtggtgttaa
    10321 aggtagatag gttgttgtag aaactgttgt agccccattc cacaactcca tgaccccaat
    10381 agctgataag agggagctgt ccttgataat ggtgataaat tcgttcccca atgctggcaa
    10441 gatatttttg actgcttgtg gcaaaatcac ataacgcatc gcatttttag gacgaatccc
    10501 tagcgaataa gccgcctcta gctgaccttt tggaaccgca ttgattccgg cacgaacagt
    10561 ctccgaaaca taagcaccac tattcataga gataatcaaa atccctggaa tcagacgcga
    10621 aaaatcaaca cctaaaattc caatctgaat agtcggagca ttgatatgca taagagcaaa
    10681 ggcaatcata atttgaacca tcatcggtgt cccacggaaa atccaaacgt acaagttggc
    10741 caaccaaaca agcggtttaa actttgaacg ttgcccaaaa gccaagacaa cacccaaaat
    10801 agttcccaaa aagataacac agatagaaat aagaatcgtc acaacagccc catagttaaa
    10861 ataaggtaaa tacttaggta aaaaagaaaa attcatagtc acactgcttt ctaaaataga
    10921 atactgtatg attataacat gttttgaatt aaaatttaaa ttttttatcc aatttattta
    10981 aaaatcttta aactagcaga attaacgaga aatcttagtt ttttctagtc aagttggcct
    11041 cctttatggt aaaatagtaa cgataagaaa tgaaggagaa tcaaaatgga atcacatttg
    11101 gttagaatca tcaaccgcct tgaagcaatg gcaaacgatg gcggaaattt aaaacgtaat
    11161 tttgaacgcg aaggagttgt tgttgcagaa gttgcgtaca gccacgacga agaaaacggc
    11221 ccaatcttta cccttcgtga cgtagaagat cgcgaaacgt atacgtttga tagcattgac
    11281 ttaatcgcaa tggaaattta cgaacttctc tactaatcta aaacaagctg ggattgtccc
    11341 tgcatgtcta agtaaaatcc tttttgtctc acaaatagga tttttttata gtccaaattc
    11401 acaaaaattt tcattgtaac aacttctcaa agcttcaatc tttttacttg ctttacaccc
    11461 caatcctgtt ataatgagag tatagaattt gactattttt gacctttaaa caagtcaggc
    11521 taaagaaaga aatgaggtag atgtatgctt tgtcaaaact gtaaaattaa cgactcaaca
    11581 attcatcttt acaccaatct caatggaaaa caaaaacaaa ttgacctctg tcaaaactgc
    11641 tataagatta tcaaaacaga tcctaacaat agcctcttca aaggtatgac ggatctgaac
    11701 aatcgtgact tcgatccctt tggtgatttc ttcaatgatc taaacaattt cagaccttct
    11761 agcaatactc ctcctattcc cccaacccaa tcaggtggag gttacggtgg aaacggcggt
    11821 tatggttccc aaaatcgtgg atctgctcaa actccgccac ctagccaaga aaaaggcctg
    11881 ctggaagaat ttggtattaa tgtaactgaa attgcccgtc gtggagacat tgaccccgtt
    11941 attgggcgcg acgatgagat tatccgtgtc atcgagattc tcaatcgtag aaccaagaat
    12001 aatcctgtcc ttatcggtga acctggtgtc ggaaaaacgg ccgttgtcga aggtctagct
    12061 cagaaaattg tcgatggcga tgtgccacat aaactccaag gtaaacaagt catccgtctg
    12121 gatgtggtta gcttagttca aggaacgggg attcgaggac aatttgaaga acgcatgcaa
    12181 aaactcatgg aagaaattcg caaacgtgaa gacatcatcc tctttatcga tgaaatccat
    12241 gaaattgttg gtgctggttc tgcgagtgat ggtaatatgg acgcaggaaa tatcctcaag
    12301 ccagcccttg ctcgtggaga actgcaacta gtcggtgcta ctaccctcaa tgaataccgt
    12361 atcattgaaa aggatgctgc cctcgagcgt cgtatgcagc ctgttaaagt cgatgaacca
    12421 acggtggatg aaacaatcac tattctcaaa gggattcaaa agaaatacga agattaccac
    12481 cacgttcaat ataccgatgc tgcgattgaa gcagctgcaa ctctttccaa tcgctacatc
    12541 caagatcgct tcttgcctga caaggccatt gacctcctag atgaagctgg ttctaagatg
    12601 aacttgacct tgaattttgt ggatcctaaa gtaattgatc agcgcttgat tgaggctgaa
    12661 aatctcaagt ctcaagctac acgagaagaa gattttgaga aggcggccta cttccgcgac
    12721 cagattgcca agtataagga aatgcaaaag aaaaagatca cagaccagga tactcctatc
    12781 atcagcgaga aaactattga gcacattatc gagcagaaaa ccaatatccc tgttggtgat
    12841 ttgaaagaga aagaacaatc tcaactcatc catctagccg aagatctcaa gtctcatgtt
    12901 attggccaag atgatgcagt cgataagatt gccaaggcta ttcgccgtaa tcgtgtcgga
    12961 cttggtaccc ctaaccgccc aatcggaagc ttcctcttcg ttgggccaac tggtgtcggc
    13021 aagacagaac tttccaaaca actggctatc gaactttttg gttctgctga tagtatgatt
    13081 cgctttgata tgagtgaata catggaaaaa catagtgtgg ctaagttggt cggcgctcct
    13141 ccaggttatg ttggctatga tgaggctggt caattaactg aaaaagttcg ccacaatcca
    13201 tattctctca tccttctcga tgaagtggaa aaagctcacc cagatgttat gcacatgttt
    13261 cttcaagtct tggacgatgg tcgtttgaca gacgggcaag gacgcaccgt tagcttcaag
    13321 gatgctatca ttatcatgac ctcaaatgca ggtacaggaa agaccgaagc tagcgttgga
    13381 tttggtgctg ctagagaagg acgtaccaat tctgtcctcg gtgaactcgg taacttcttt
    13441 agcccagagt ttatgaaccg ttttgatggc attatcgaat ttaaggctct cagcaaggat
    13501 aacctccttc agattgtcga gctcatgcta gcagatgtta acaagcgcct ctctagcaac
    13561 aacattcgtt tggatgtaac tgataaggtc aaggaaaagt tggttgacct aggttatgat
    13621 ccaaaaatgg gagcacgccc acttcgtcgg actattcaag actatattga ggacacaatc
    13681 actgactact accttgaaaa tccaagcgaa aaagatctca aagcagttat gactagcaag
    13741 ggaaacattc agattaaatc tgccaaaaaa actgaagtta aaagttctga aaaagaaaaa
    13801 taaatcctat aaaaaaagag tagaaaatga aatttttctg cttctttttt tactaaaata
    13861 actgtaattt cttgacagct tgccctttgt ccattatga
//
LOCUS       DAVLHM010000049        13423 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLHM010000049 DAVLHM010000000
VERSION     DAVLHM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.049"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(177..1808)
                     /locus_tag="VXE45_001771"
     CDS             complement(177..1808)
                     /locus_tag="VXE45_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0789770.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2101..7080
                     /locus_tag="VXE45_001772"
     CDS             2101..7080
                     /locus_tag="VXE45_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0789771.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7170..8366
                     /locus_tag="VXE45_001773"
     CDS             7170..8366
                     /locus_tag="VXE45_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0789772.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8502..9029
                     /locus_tag="VXE45_001774"
     CDS             8502..9029
                     /locus_tag="VXE45_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0789773.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRVRLFLEKKEK"
     gene            9106..9462
                     /gene="glnR"
                     /locus_tag="VXE45_001775"
     CDS             9106..9462
                     /gene="glnR"
                     /locus_tag="VXE45_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0789774.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9499..10845
                     /gene="glnA"
                     /locus_tag="VXE45_001776"
     CDS             9499..10845
                     /gene="glnA"
                     /locus_tag="VXE45_001776"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0789775.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10941..11060)
                     /locus_tag="VXE45_001777"
     CDS             complement(10941..11060)
                     /locus_tag="VXE45_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0789776.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11605..12924
                     /locus_tag="VXE45_001778"
     CDS             11605..12924
                     /locus_tag="VXE45_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0789777.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYGNKDETTSYPIYEIPEAWRYIKF
                     ASLVNFRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDIS
                     PKGTLLMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGD
                     SKDAIKGKTLNSTSISELLIPISNHEEMKRIIFKVDLLFQKVSQLFE"
     gene            complement(12878..>13423)
                     /locus_tag="VXE45_001779"
     CDS             complement(12878..>13423)
                     /locus_tag="VXE45_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0789778.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKALTKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQL"
BASE COUNT         4388 a         2407 c         2804 g         3824 t
ORIGIN      
        1 aaaatgaaat aataacagga caaatcgatt tctaacaatg ttttagaaat agaggtgtac
       61 tattctagtt tcaatatact atatatctgc agaatactct ttcagtttca ttcagcctag
      121 tcttgcttag gaaaaagtaa gaagccatcc aattatgatg gatagcttct tggttattag
      181 atttgttctg caaaaacctt ttcagcaagg ttcatagcgt ggtctgatac acgagtgtag
      241 tgtgagatga tgtcgataaa gttgacccca gcttgtgttg aacattcgcc tttgttgagg
      301 cgtttgatgt gggtttttct gagaacacgt tctatcttat tgattgcttc atgacgttct
      361 acaagactgc gtgctttttc aatatcattg ttttccacac tatccagagc atctttgata
      421 aagtcactag tttggcggta aacttcctct aattctttca aggcggcatc agaaaattca
      481 acatttttcc gttgaagata gtcagtcaga ttgagtagag cctccgtgtg gtctccaatc
      541 cgttccaaat cacgggagga atcaaggata ttggtaagca cttcactttc tttttggctg
      601 agagcttcgc ttgaaagggc aatgagataa cgtgttaatt gctcatcgat ggtgttaatt
      661 gcttcttcgg ttttatgccc tttttcagca actttttcat ccaagtcaat gatgtactta
      721 taggaaaggt caaaggcttt agcagcgtag tttcctaagt gcaagagctc tttcttagca
      781 tttcctagag cgatagatgg ggcctgtttg atgaaatgtt catcaagata taagggttcg
      841 tatttgacaa cctcgtcctc tccaggaata atcttggtta caaagtaagc cagagctccg
      901 ataaatggaa attggacaat ggtgttggta atattaaagg ttccgtgagc aaaggcgatg
      961 gtcatttccg gtgctagatt tagcgtagct tcaaaccaat gaatcaggac agtaaaagga
     1021 actagaaaaa taacgcagac gactgttccg ataatgttga aggcaacatg agctcctgct
     1081 acccgtttag ctgcaatatt agcccctaaa gaggcaatga tggctgtaat ggttgtcccg
     1141 atattgtcac caaatagaac tggcaaagct ccctgtaggt caattagatt gccggcgtag
     1201 aggttttgta aaatcccaat ggtagccgaa gaagcttgaa ttagcaaggt caagccagta
     1261 ccgacaaaga cacccaaaac aggattctta cttagctcaa tcatatagtc cttaaagacc
     1321 tgtaaatcct tgagtggagc cattgcgccg ctcatgagat tgagggcaaa aaagatacca
     1381 ccgataccaa agaggatgcg tccgatatta ttgactgtcc gatttttcgt aaaaaagaga
     1441 cagacggcac cgataaagag cataggtagg gcatagttac ctaatttaaa accgatgaga
     1501 aaggatgtga cagttgtccc aatattagca cccatgacaa tcccgatagc ctgacgtaag
     1561 gttaagagac cggcactgac caggccgact gtaataactg ttacaccaga actagactga
     1621 attagagcag tcatcccaat accaaccaga actccaaaga aaggattact agtatatttg
     1681 tcaatgtaaa aacgaaggcg atctccagca gcttgttgca aaccgtctcc catggtcttg
     1741 atgctatata agaatagccc cagaccacct aaaaagtgaa ataaaatttc ctgccaatta
     1801 atggacattt ctttttcctc cgaaaaataa tcgcggaata tctcctattc tattttaaag
     1861 gataaaagta aatctaacaa gtgttaacgt caagtttgta aaagaaaatt ataattgata
     1921 agtgtattat ttttaagagt ttttaacctt attttagatt tatgaaagca gctattgttt
     1981 tttgtctaaa aatgttttag gataaaaatg tgattatcat ggttctagag tttgataaaa
     2041 aactacagaa tataaagcgc tttcttgaaa acaacaaaat caatctttta ggaggagaaa
     2101 atgaagaatc cattttttga aagacgttgt cgttacagta ttcgtaagtt atcagtagga
     2161 gcctgctcgc tgatgattgg tgctgtttta tttgctggtc cagccttggc tgaagaaact
     2221 gcagttcctg aaaatagcgg agctaataca gagcttgttt caggagagag tgagcattcg
     2281 accaatgaag ctgataagca gaatgaaggg gaacatgcta gagaaaacaa gctagaaaag
     2341 gcagaaggag tagcgatagc atctgaaact gcttcgccag caagcaatga agctgcaact
     2401 actgaaactg cagaagcagc tagcgcagct aaaccagagg aaaaagcaag tgaggtggtt
     2461 gcagaaacac catctgcaga agcaaaacct aagtctgaca aggaaacaga agcaaagccc
     2521 gaagcaacta accaagggga tgagtctaaa ccagcagcag aagctaataa gactgaaaaa
     2581 gaagtccagc cagatgtccc taaaaataca gaaaaaacat taaaaccaaa ggaaatcaaa
     2641 tttaattctt gggaagaatt gttaaaatgg gaaccaggtg ctcgtgaaga cgatgctatt
     2701 aaccgcggat ctgttgtcct cgcttcacgt cggacaggtc atttagtcaa tgaaaaagct
     2761 agcaaggaag caaaagttca agccttatca aacaccaatt ctaaagcaaa agaccatgct
     2821 tctgttggtg gagaagagtt caaggcctat gcttttgact attggcaata tctagattca
     2881 atggtcttct gggaaggtct cgtaccaact cctgacgtta ttgatgcagg tcaccgtaac
     2941 ggggttcctg tatacggtac actcttcttc aactggtcta atagtattgc agatcaagaa
     3001 agatttgctg aagctttgaa gcaagacgca gatggtagct tcccaattgc ccgtaaattg
     3061 gtagacatgg caaagtatta tggctatgat ggctatttca tcaaccaaga aacaactgga
     3121 gatttggtta aacctcttgg agaaaagatg cgccagttta tgctctatag caaggaatat
     3181 gctgctaagg taaaccatcc aatcaagtat tcttggtatg atgccatgac ctataactat
     3241 ggacgttacc atcaagatgg tttgggagaa tacaactacc aattcatgca accagaagga
     3301 gataaggttc cggcagataa cttctttgct aactttaact gggataaggc taaaaatgat
     3361 tacactattg caactgccaa ctggattggt cgtaatcctt atgatgtatt tgcaggtttg
     3421 gaattgcaac agggtggttc ctacaagaca aaggttaagt ggaatgacat tttagacgaa
     3481 aatgggaaat tgcgcctttc tcttggttta tttgccccag ataccattac aagtttagga
     3541 aaaactggtg aagattatca taaaaatgaa gatatcttct ttacaggtta tcaaggagac
     3601 cccactggcc aaaaaccagg tgacaaagat tggtatggta ttgctaacct agttgcggac
     3661 cgtacgccag cggtaggtaa tacttttact acttctttta atacaggtca tggtaaaaaa
     3721 tggttcgtag atggtaaggt ttctaaggat tctgagtgga attatcgttc agtatcaggt
     3781 gttcttccaa catggcgctg gtggcagact tcaacagggg aaaaacttcg tgcagaatat
     3841 gattttacag atgcctataa tggcggaaat tcccttaaat tctctggtga tgtagctggt
     3901 aagacagatc aggatgtgag actttattct actaagttag aagtaactga gaagaccaaa
     3961 cttcgtgttg cccacaaggg aggaaaaggt tctaaagttt atatggcatt ctctacaact
     4021 ccagactaca aattcgatga tgcagatgca tggaaagagc taaccctttc tgacaactgg
     4081 acaaatgaag aatttgatct tagctcacta gcgggtaaaa ccatctatgc agtcaaacta
     4141 tttttcgagc atgaaggtgc tgtaaaagat tatcagttta acctaggaca attaactatc
     4201 tcggacaatc accaagagcc acaatcgccg acaagctttt ctgtagtgaa acaatctctt
     4261 aaaaatgccc aagaagcgga agcagttgtg caatttaaag gcaacaagga tgcagatttc
     4321 tatgaagttt atgaaaaaga tggagacagc tggaaattac taactggctc atcttctaca
     4381 actatttatc taccaaaagt tagccgctca gcaagtgctc agggtacaac tcaagaactg
     4441 aaggttgtag cagtcggtaa aaatggagtt cgttcagaag ctgcaaccac aacctttgat
     4501 tggggtatga ctgtaaaaga taccagccta ccaaaaccac tagctgaaaa tatcgttcca
     4561 ggtgcaacag ttattgatag tactttccct aagactgaag gtggagaagg tattgaaggt
     4621 atgttgaacg gtaccattac tagcttgtca gataaatggt cttcagctca gttgagtggt
     4681 agtgtggata ttcgtttgac caagccacgt accgttgtta gatgggtcat ggatcatgca
     4741 ggagctggtg gtgagtctgt taacgatggc ttgatgaaca ctaaagactt tgacctttat
     4801 tataaagatg cagatggtga gtggaagcta gctaaggaag tccgtggtaa caaagcacac
     4861 gtgacagata tcactcttga taaaccaatc actgctcaag actggcgctt gaatgttgtc
     4921 acttctgaca atggaactcc atggaaggct attcgtatct ataactggaa aatgtatgaa
     4981 aagcttgata ctgagagtgt caatattccg atggccaagg ctgcagcccg ttctctaggc
     5041 aataacaagg tacaagttgg ctttgcagat gtaccggctg gagcaactat taccgtttat
     5101 gataatccaa attctcaaac tccgctcgca accttgaaga gcgaagttgg aggagaccta
     5161 gcaagtgcac cattggattt gacaaatcaa tctggtcttc tttattatcg tacccagttg
     5221 ccaggcaagg aaattagtaa tgtcctagca gtttccgttc caaaagatga cagaagaatc
     5281 aagtcagtca gcctagaaac aggacctaag aaaacaagct acgccgaagg ggaggatttg
     5341 gaccttagag gtggtgttct tcgagttcag tatgaaggag gaactgagga cgaactcatt
     5401 cgcctaactc acgcaggtgt atcagtatca ggttttgata cgcatcataa gggagaacag
     5461 aatcttactc tccaatattt gggacaaccg gtaaatgcta atttgtcagt gactgtcact
     5521 ggccaagacg aagcaagtcc gaaaactatt ttgggaattg aagtaagtca ggaaccgaaa
     5581 aaagattacc tagttggtga tagcttagac ttgtctgaag gacgctttgc agtggcttat
     5641 agcaatgaca ccatggaaga acattccttt actgatgagg gagttgaaat ttctggttac
     5701 gatgctcaaa agactggtcg tcaaaccttg acgcttcatt accaaggcca tgaagttagc
     5761 tttgatgttt tggtatctcc aaaagcagca ttgaacgatg agtacctcaa acaaaaatta
     5821 gcagaagttg aagctgctaa gaacaaggtg gtctataact ttgcttcatc agaagtaaaa
     5881 gaagccttct tgaaagcaat tgaagcggcc gaacaagtgt tgaaagacca tgaaactagc
     5941 acccaagatc aagtcaatga ccgacttaat aaattgacag aagctcataa agctctgaat
     6001 ggtcaagaga aatttacgga agaaaagaca gagcttgatc gcttaacagg tgaggttcaa
     6061 gaactcttgg ctgccaaacc aaaccatcct tcaggttctg ccctagctcc gcttcttgag
     6121 aaaaacaagg ccttggttga aaaagtagat ttgagtccag aagagcttac aacagcgaaa
     6181 cagagtctaa aagatctggt tgctttattg aaagaagaca agccagcagt cttttctgat
     6241 agtaaaacag gtgttgaagt acacttctca aataaagaga agactgtcat caagggtttg
     6301 aaagtagagc gtgttcaagc aagtgctgaa gagaagaaat actttgctgg agaagatgct
     6361 catgtctttg aaatagaagg tttggatgaa aaaggtcaag atgttgatct ctcttacgct
     6421 tctattgtga aaatcccaat tgaaaaagat aagaaagtta agaaagtatt tttcttacct
     6481 gaaggcaaag aggcagtaga attgactttt gaacaaacgg atagtcatgt tatctttaca
     6541 gcaccacact ttactcatta tgcctttgtt tatgaatctg ctgaaaaacc acaacctgct
     6601 aaaccagcac cacaaaacaa agtccttcca aaacctactt atcaaccgac ttctgatcaa
     6661 caaaaggctc ctaaattgga agttcaagag gaaaaggttg cctttcatcg tcaagagcat
     6721 gaaaatgctg agatgctagt tggggaacaa cgagtcatca tacagggacg agatggactg
     6781 ttaagacatg tctttgaagt tgatgaaaac ggtcagcgtc gtcttcgttc aacagaagtc
     6841 atccaagaag cgattccaga aattgttgaa attggaacaa aagtaaaaac agtaccagca
     6901 gtagtagcta cacaggaaaa accagctcaa aatacagcag ttaaatcaga agaagcaagc
     6961 aaacaattgc caaatacagg aacagctgat gctaatgaag ccctaatagc aggcttagcc
     7021 agcctcggtc ttgctagttt agccttgacc ttgagacgga aaagagaaga taaagattaa
     7081 atatcgaaaa atcttgtgaa atctttcctt atatttccaa agtgtgatat aatagtttcg
     7141 aataaaataa ataaaggagt ttttgtaaca tggcaaaact tactgttaaa gacgttgact
     7201 tgaaaggtaa aaaagtcctc gttcgtgttg acttcaacgt accattgaaa gatggcgtaa
     7261 tcactaacga taaccgtatc acagcagctc ttccaactat taagtacatc atcgaacaag
     7321 gtggacgtgc aattcttttc tctcaccttg gacgtgtgaa agaagaagct gataaagctg
     7381 gtaaatcact tgctcctgta gcagctgact tggcagcaaa acttggtcaa gatgttgttt
     7441 tcccaggtgt cactcgtggt gctgaattgg aagcggcaat caacgctctt gaagatggac
     7501 aagttctctt ggttgaaaac actcgttacg aagatgttga cggcaagaaa gaatctaaaa
     7561 acgatcctga acttggtaaa tactgggcat cacttggaga tggtatcttc gtaaacgatg
     7621 cattcggtac agctcaccgt gcacacgcat ctaacgttgg tatctcagca aacgttgaaa
     7681 aagcagttgc tggtttcctt cttgaaaacg aaattgccta catccaagaa gcagttgaaa
     7741 ctccagaacg tccattcgtg gctatccttg gtggttcaaa agtttcagac aagatcggtg
     7801 ttatcgaaaa cttgcttgaa aaagctgata aagtccttat cggtggtggg atgacttaca
     7861 cattctacaa agcacaaggt atcgaaatcg gtaactcact tgtagaagaa gacaaattgg
     7921 atgttgcgaa agctcttctt gaaaaagcaa atggtaaatt gatcttgcca gttgactcaa
     7981 aagaagctaa cgcatttgct ggttacactg aagtgcgtga cactgaaggt gaagcagttt
     8041 ctgaaggctt ccttggtctt gacatcggtc caaaatctat cgccaaattt gacgaagctt
     8101 tgactggtgc caaaacagtt gtatggaacg gacctatggg tgtatttgaa aacccagatt
     8161 tccaagctgg tacaatcggt gtgatggacg ctatcgtgaa acaaccagga gttaaatcaa
     8221 tcatcggtgg tggtgactca gctgccgcag cgattaacct tggccgtgca gacaagttct
     8281 catggattag tacgggtggt ggagcatcaa tggaacttct tgaaggtaag gttcttccag
     8341 gacttgcagc cctgacagaa aaataagatt ttataaacaa atcaaagaag agagggatga
     8401 aagttcctct tttcttttgc ttaaaataaa aacgcttcct ctcaactatt actcataaaa
     8461 atcaccgatt tatgataaaa tggaaataga aagttgagat tatgagttat tttaaaaaat
     8521 ataaattcga taaatcccag ttcaaacttg gtatgcgaac ctttaaaaca ggtattgctg
     8581 tttttctagt tctcttgatt tttggctttt ttggctggaa aggtcttcaa attggtgctt
     8641 tgacagccgt ttttagcctg agggagagtt ttgatgagag tgttcatttt gggacttcgc
     8701 gtattctagg aaatagtatc ggtggactct atgccttggt cttcttctta ttaaatacct
     8761 ttttccacga agccttttgg gtgaccttgg tagttgttcc aatctgcacc atgttaacca
     8821 ttatgacaaa tgtagccatg aataacaaag caggggttat tggtggtgta gcagctatgt
     8881 taatcattac cctatcaatt ccaagtggtg agacaatttc gtacgtgttt gtgcgtgtat
     8941 cagaaacgtt tatgggagtt tttgtcgcaa ttatcgtaaa ttacgatatt gatcgtgttc
     9001 gtctcttttt agagaaaaaa gaaaaataat gttacatttt ataacattat caattgacgt
     9061 ttgtcttttt ttagactata atagacagaa agaaggaaat tgtaaatgaa ggaaaaagaa
     9121 tttcgccgaa atatggctgt ttttcctatc ggcagtgtta tgaagttgac cgatctatcg
     9181 gcgcgtcaga ttcgttatta tgaagatcaa gagttgatca agcccgatcg aaacgaagga
     9241 aatcgtcgca tgtattcctt gaatgacatg gatcgtctgc ttgaaatcaa agattatatc
     9301 tctgaaggtt ataatatcgc tgccattaag aaaaaatatg ctgaacgtga agcgaaatcc
     9361 aagaaagcgg ttagtcagac tgaagtacgt cgtgcacttc acaatgaact cctccaacag
     9421 gggcgttttg cttcagtaca gtcacctttt ggtcgcggtt aggcaaccgc aagtagtcat
     9481 agattaagga gaaaacttat gccaatcaca gctgcagata ttcgtcgtga agtcaaggaa
     9541 aaaaatgtta cctttattcg tcttatgttc tcagatattt tgggaaccat gaaaaacgtc
     9601 gaaattcctg ctacagatga acagttagat aaggttttgt cgaacaaggt tatgtttgat
     9661 ggatcttcta ttgaaggttt tgtacgtatc aatgagtcgg atatgtactt gtacccggac
     9721 ttggatacat ggacagtctt cccttgggga gatgaaaatg gaagtgttgc aggtctgatc
     9781 tgtgatgtct atacaacaga aggtgaacca tttgcgggtg accctcgtgg taatttgaaa
     9841 cgagctcttc gtcacatgga agaagttgga ttcaaatcct tcaaccttgg tccagagcca
     9901 gaattcttcc tatttaagtt ggatgaaaat ggggacccaa cacttgaagt gaatgacaag
     9961 ggtggctact ttgatttggc acctactgac cttgcggaca acacacgtcg tgagattgtg
    10021 aatgtcttga ccaaaatggg atttgaagta gaagcgagtc accacgaggt tgcggttgga
    10081 cagcatgaga ttgactttaa gtacgatgaa gttctccgtg cttgtgataa gattcaaatc
    10141 tttaaacttg ttgttaaaac cattgctcgc aaacacggac tttacgcaac atttatggcg
    10201 aagccaaaat ttggtattgc tggctcaggt atgcactgta atatgtcctt gtttgatgca
    10261 gaaggaaata acgccttctt tgatccaaat gatccaaaag gaatgcagtt gtcagaaaca
    10321 gcttaccatt tcctaggcgg tttgatcaag catgcttaca actatactgc catcatgaac
    10381 ccaacagtta actcatacaa acgtttggtt ccaggttatg aagcgcctgt ttacattgct
    10441 tgggctggtc gtaaccgttc gccacttgtg cgcgtacctg cttcacgtgg tatgggaact
    10501 cgtcttgagt tgcgttcagt ggatccaatg gcgaaccctt acattgctat ggctgttctt
    10561 ttggaagttg gtttgtatgg tattgaaaat aaaatcgaag caccagctcc tatcgaagaa
    10621 aatatctaca tcatgacagc agaagagcgc aaggaagctg gtattacaga ccttccatca
    10681 actcttcaca acgctttgaa agctttgaca gaagatgaag tggttaaagc tgctctcgga
    10741 gatcacatct acactagctt ccttgaagcc aaacgaatcg aatgggcaag ttatgcaacc
    10801 ttcgtttcac aatgggaaat tgataattat ttagaccttt actaatacta atatagaaga
    10861 aagattgcct gtgggtaaac agtcacacag cagtctaagc catcaaatac ctataaccct
    10921 taaaatagcg atttcggtcg ctatttattt ttcgaaaaat cctcttgact cttttgcgaa
    10981 ttagatttat catcagacgt gtagaagaaa attaaggagt cactatggaa aaattcaatt
    11041 tcaaaaacaa tatcgggcaa gaaaacaagt tacttcaaat cgaaatctac aagtttacta
    11101 acttttgcaa gcttcaaaat tacacatctg taaatatttt ttcgaaagat atatttgaag
    11161 ccatagtaaa ttgagactag aatggtacac tacatctgct aaaaatttct agaaactaat
    11221 ttaactttcc taatcgattt gtttacatct tatttcaatc tactatatta tctcaataaa
    11281 tgatgatggc gactgttttg tttgtgcttg tcgatttttg aatcctgatc gagcggaaga
    11341 atatttctgc cgaggttgcc aaggggaaaa tcctgaagat attgaatttt atgatgaaca
    11401 attacaggca gaaaaggtgg aggttttgaa tattcgattg gaagtaaaaa attgaattat
    11461 ctacaatctc atcaacaata aacctatttc aaccccatta tctataggcg tatttttacg
    11521 cctttttata tacttgaagc acataagaaa cattatggga agtttgctga tggaagtact
    11581 caagaaattg atgttcctta tgatattcct gatacttggg agtgggtgag gttttctaca
    11641 ttggttgaaa ttgtcagagg tggctctcca cgaccaatca aagattatct tacttctgaa
    11701 gtagatggaa taaattggat aaaaataggt gatactgaaa agggtgaaaa gtatataaat
    11761 aatgttaaag aaaaaatcaa aaaatcaggg cttaacaaaa ctagatttgt aaaaaaaggt
    11821 acatttttgt taactaattc tatgagtttt ggtagacctt atattttgaa tgttgatggt
    11881 gcaatacacg atggatggtt ggctatttcg aactatgaaa actcattaaa taaagattac
    11941 ctattctata ttctttcatc aaatgtagtt tattctcaat ttctatctct aattagtgga
    12001 gctgttgtga aaaacttgaa tagtgataaa gttgcttcta ttcttatccc tctcccccca
    12061 ctatccgaac aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa
    12121 tatgctgaaa gttataatag actagaacag ctagataaag aatttccaga taaactaaaa
    12181 aaatctattc ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa
    12241 tcagtcgaag ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc
    12301 aagattaaaa agaaagattt ggacatttct attgtttccc aaggagatga taactcttat
    12361 tatgggaaca aagacgaaac aacctcttat cctatatatg aaatcccaga agcatggaga
    12421 tatattaaat ttgctagcct agttaacttc agaataggaa aaactcctcc acgcagtgaa
    12481 gctacttttt ggggaactga aataccttgg gtatctatat cagatatgcc tatatctggt
    12541 tatgtaacta atacgagaga atctatttct aaattagcat taaaatcaaa gaaaatagac
    12601 atttcaccta aaggaacttt attaatgagt tttaaattat ctattggaaa agttgccata
    12661 ttggatattc ctgccactca taatgaagcc attatatcga tattccccta tgctaataaa
    12721 gaaaatatta tcagagatta cttaatgata tttttgccac ttatctctac tttaggtgat
    12781 tcaaaagatg ctatcaaagg gaaaacatta aatagtacca gtatctccga attattaatc
    12841 cctatttcta atcatgaaga gatgaaaaga atcattttca aagttgattt actttttcaa
    12901 aaagtttctc aactttttga gtaataagtt cctgttcctc aaaaggagct aacggaatta
    12961 atagctcgct cagtgtagtt ttaggaatat tatataaagc ttgacctgat agtttagtta
    13021 atgctttcaa ttgtttataa aataacggag aggacaagtt aaataataga aattttgaaa
    13081 taatctctga actttcgaat ggtgttaatt ggaaaataaa tccaccagcc acaacaccat
    13141 catagtcttt atcgattctt gcaaactttc caatatgttc taaagaggtt gatacaggtg
    13201 ttattagctg attatgtttt aaataaactt gctcagagga gatgaattgt gtatcaatgt
    13261 agtaatcgtt atccaacaga gaaaattcta aaggcttaat attaccacca cgtataattc
    13321 taacaccttt attattaatg cttaaatcgc ccttcttgta agaaagacct gtattcattg
    13381 aaaaaatatc ttttattttt ataacaaccc aattcatagg tat
//
LOCUS       DAVLHM010000050        12922 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLHM010000050 DAVLHM010000000
VERSION     DAVLHM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.050"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..152
                     /locus_tag="VXE45_001780"
     CDS             <1..152
                     /locus_tag="VXE45_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0789779.1"
                     /translation="NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKF
                     VLSRA"
     gene            complement(238..1440)
                     /gene="rpsA"
                     /locus_tag="VXE45_001781"
     CDS             complement(238..1440)
                     /gene="rpsA"
                     /locus_tag="VXE45_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0789780.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1602..1673)
                     /locus_tag="VXE45_001782"
     tRNA            complement(1602..1673)
                     /locus_tag="VXE45_001782"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1639..1641),aa:Gln,seq:ttg)
     gene            complement(1683..1763)
                     /locus_tag="VXE45_001783"
     tRNA            complement(1683..1763)
                     /locus_tag="VXE45_001783"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1727..1729),aa:Tyr,seq:gta)
     gene            complement(1813..2043)
                     /locus_tag="VXE45_001784"
     CDS             complement(1813..2043)
                     /locus_tag="VXE45_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0789781.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2211..2855)
                     /gene="pcp"
                     /locus_tag="VXE45_001785"
     CDS             complement(2211..2855)
                     /gene="pcp"
                     /locus_tag="VXE45_001785"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0789782.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2870..3793)
                     /locus_tag="VXE45_001786"
     CDS             complement(2870..3793)
                     /locus_tag="VXE45_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0789783.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3790..4479)
                     /locus_tag="VXE45_001787"
     CDS             complement(3790..4479)
                     /locus_tag="VXE45_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0789784.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4544..5248)
                     /locus_tag="VXE45_001788"
     CDS             complement(4544..5248)
                     /locus_tag="VXE45_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0789785.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5304..6326)
                     /locus_tag="VXE45_001789"
     CDS             complement(5304..6326)
                     /locus_tag="VXE45_001789"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0789786.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6456..8927)
                     /gene="parC"
                     /locus_tag="VXE45_001790"
     CDS             complement(6456..8927)
                     /gene="parC"
                     /locus_tag="VXE45_001790"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0789787.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9347..11290)
                     /gene="parE"
                     /locus_tag="VXE45_001791"
     CDS             complement(9347..11290)
                     /gene="parE"
                     /locus_tag="VXE45_001791"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0789788.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11426..12067
                     /gene="plsY"
                     /locus_tag="VXE45_001792"
     CDS             11426..12067
                     /gene="plsY"
                     /locus_tag="VXE45_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0789789.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12110..12922)
                     /locus_tag="VXE45_001793"
                     /pseudo
     CDS             complement(12110..12922)
                     /locus_tag="VXE45_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3708 a         2892 c         2284 g         4038 t
ORIGIN      
        1 ctaatgccaa actggaagcg accaataatc tcatcaaact tatcaagcgc aatgcctttg
       61 gttttcggaa ctttgaaaac ttcaaaaaac ggattttcat cgctctgaat atcaaaaaag
      121 aaaggacgaa atttgtcctt tctcgagctt agcttttttt caacccacta cagttgacaa
      181 agagccagaa aaatcctttg tttagtaaac aaaggatttt gtgaattttc aatttgatta
      241 aagttcgata tcaccaaaca aatcagccat tgaaaatcct gtttgtgttt ctggaagttc
      301 gaaatcacgc ttttcttgac gtcttggacg acgtggacga gcaacacgtt tttcttcttt
      361 ttgtccttct tcttgggctg gacgttcttc aagagcttta atagaaagtg acacgcgttc
      421 tgcatctgcg ttaacttcaa gaactttaac ttgaacttct tgaccaactt taagagcttc
      481 ttttggattt tcaatccgtt tgtgtgaaat ttgtgatacg tgaacaagtc catcgatacc
      541 tggcaatact tcaacaaatg caccgaagtc agtcaaacgt ttaactgttc cttctactac
      601 atcaccttta gccaattttt gctcaacgcc atcccatggt cctggtactg ttgctttaag
      661 tgaaagtgat acacgtcctt cttcttcgtt aagatcaagg attttcactt caatttcttc
      721 accaacagtt acaactgatt ttggtgatac attacgttca tgtgacaatt cagtcaagtg
      781 aaccaatccg tcaacaccac caagatcgac gaaagcgccg aagcttgtga tacgagcaac
      841 tttaccagtt acaacatcac caacagccaa tttaccgaat acttcagcgc gagctgctgc
      901 agtagctgct tcaacaactt cacgacgtga aaggatgaag cggttttctt tagcgttaac
      961 ttctttgatt ttagtatcaa attcttgacc tacaaaacgc tcagcgttac gtacgaaacg
     1021 agtatccaac attgaagctg ggataaatcc acgaacacct tcaaattcta ctgaaagtcc
     1081 acctttaacg gcacgcgttc ctttaacagt aacaacttct tcttcgcgac caacaagttt
     1141 gtcccatgct ttgcgagctt caaggcgttt tttagataca aggtatgtaa ctgtatcagt
     1201 atctttacca actacttgac gaagtacaag aacatccaat acttctccta ctttaacaaa
     1261 gtcattgata tctgcatcac gatcgtttgt caattcgcga agagtcaaga caccttcaac
     1321 accagttcca gagattgcaa cgttagcttg agtcgcatca actgtcaata cttcagcact
     1381 aacaacatca ccagtctcaa cttgactaac gctatttagc aaatcttcaa attcattcat
     1441 ctaaaaaatc ctccaacaat caagtttttc ttaaacttga catacttata atttttttcc
     1501 taagcacccg caaggacatg ttcatatcat tcacgtcttt caattataaa aataaaatac
     1561 cctaagatat tttgcttttt atcttgatta ttacctaaga actggggtag ctggattcga
     1621 accaacgcat gagggagtca aagtcccttg ccttaccgct tggctatacc ccattaatga
     1681 aatggagaga gagggattcg aacccccgaa cccgaaggag cggatttaca gtccgccgcg
     1741 tttagcctct tcgctatctc tcctacaatc aacatggact attatatcat gaaaatttca
     1801 aaaaaacaag acttattttg ctaaattata attttcaatc aaaatttcca cagctttttc
     1861 caatttttta taaaaactat cgacattccc attctttata atggcaaatt gtccgtctaa
     1921 ttcggcaatt tctccgataa cttttttacc gatagtcaat gtataacctt caaaactgtc
     1981 tttaccaaca ttaactttgg catccgctac ttgaatttcg atttttttat ctttcttgct
     2041 catttcatac ctctcttcac tttttctatt ttacaagaaa atcctaaaac tagcaagaaa
     2101 aaactctata tcaggcttct ctgatataga gttttatgta aacaacctca atcgatttag
     2161 catagttaat agttagtaaa caagcataat tgactatcct ttttaggtta tcagtgagtc
     2221 tcaccgccta ctaactgcaa atccttatct ttgtagtcta caatagcttc aatagctacc
     2281 tctatgcctc ttacaatatc acatagactc attcctgcag tattcggctt atttactact
     2341 tgttccatca tatatggaat atgcatgaaa cctgctctca tattagggaa ttttttatcc
     2401 actaaataaa gagcttggta catcaaatga ttgcaaacaa aggttcctgc actattggat
     2461 acaactgccg gaagtccctg ttttttgata gcttgtacca tcgctttgat aggtaaacta
     2521 ctaaaatagg ccgatgctcc atcaatacga atcggtgtat caattggttg attgccttcg
     2581 ttatcaggta tgcgagcatc atcttgatta atagccactc gttcaggtgt taagccggtc
     2641 ctgccgcctg cttgtccaat acaaagtaca gcatctggtt gatatcgtaa tatttctgcc
     2701 tctaaaactt ctgacgactt ataaaaaacc gttggaattt ctacccagcg aacttcagcc
     2761 ccattaatct cagatggtaa taattttaca gcctccaaag ctggattaat cttttcacct
     2821 ccaaaaggat taaaacctgt aaccaatatt ttcattttat tttcctttac taaaatgcga
     2881 gaaagtacat taagaatatg tgaataacaa tcattactag agcaacacct gcttgagcct
     2941 ttataacgcc attctgatct ttcatatcca tcaatgctgc tggtagagcg ttaaaattag
     3001 cagccattgg ggtcaataag gtcccacaat aacctgctgt catggcaaga gcaccagcca
     3061 caattggatt agctcccaga gcaaatacga agggaactcc aacacctgct gtaataacgg
     3121 tgaatgctgc aaaagcattt cccataatca ttgtgaatag aaccattcca agaacatagg
     3181 ccaaaactcc tataaagcga ctatctgaag gaacaatacc gctaatcaga tgagagataa
     3241 catcaccaac acctgctaca gtaaaaatag cccccaaagc ccctaataat tgaggaacaa
     3301 tcccacttgt tgaaacttgc tgagtcattc gattattttc tgataacaga ctcttagggt
     3361 gactattggt aatcacaaga acagaaattg tagcaaacaa ggcggcaagg ctaatcgaaa
     3421 tcttgctaaa ttctggaatc atttgcgcta agaccaacgc aagtattgcc atcagcataa
     3481 ctggaataaa aattttattt ttcaacctgt tagattcaat attggctttc atttcatcta
     3541 aggatggcaa ggttccgata cggacttgct taaacaatgt taacagcgat aataggatta
     3601 caataatacc aatactcata tttggcatat aggaaccacc tataaacgta atagacaata
     3661 gagtccaaaa tgcagatgtc ccaagtcgaa ctgggtttgt tttatcttta taactacaat
     3721 aggctgtatg gagaaattga caaccaatca caatataggt caactctaat agttgctttg
     3781 ccaactctgt catttttgtt ctcctcccct agtctttttt gatatcaatt ttttatcaaa
     3841 taaataattg taaatcccca ctacaataag tgttataaca gcaacaataa tagatgtaga
     3901 agcaatccct gcataattgc tttcatagcc taactgatct aatgttcccc ctatcaagag
     3961 gactccccca gcacctacaa acgtattttg agcaaagaaa tttccaaaat tttcattcgc
     4021 agccgcacgc gcttttattg tctcatcttc aacctctgtt aactttctac ctaattgaga
     4081 ctctgcagct gcttctccca taggttgaac caaaggtctg acaaactgag ggtgtcctcc
     4141 tagacgaatt gaaaagaaac cagctaactc tcgaataaag aaataaactg tatagaagtt
     4201 tccaactgtc agacctttaa tctttcgaat caaatcgatt gatcgttgct tgagtccaaa
     4261 ggtttctgac agccccacaa gaggcaaggt aaccataaaa atcgtgagca ctcgctgatt
     4321 gctaaattct tttcccaaaa tctccaaaaa ttcaacgaga gaaacacctg aaactaaagc
     4381 tgtaaccaaa ccagctaaga ctactgttgc aattgtatca aattttaaaa taaaacccac
     4441 aacaatgatt gctattccta ttaatctaat ccactccata tcaaactcct ttatattcaa
     4501 aatgacagta ttttaaaaat tttatcaaga tcaataccat tccttattta atgtgttttt
     4561 ctagttcttt ttggtatttg ctattggatt ccaatttttc tttttgccat tttttaaaaa
     4621 cctcgttata ttcttttgtt gtaacaatat ctttttgcaa tttcattcct ttaaagatat
     4681 atggttcccc cttaatacca acttgtgagt atggttttga gaatggtact acgttactta
     4741 caattggaga accaccagat gaagctgttg gcatcaataa tgaactatct gtcgaccaag
     4801 cttgagcttt ggcatatttt tcatatctct tctctaggtc agtggtctca gaaacagcat
     4861 cttctaacaa tttcttatat ttatccaaac caggtttagc tacaacatcc ttatcttttc
     4921 ctttcgtaat accaaggtgt ttcatggcag aaccagattt tggatccata atattcaagt
     4981 aagacgctgg atcttgatag cttggagccc atcctgtact attcaaatca tagtcttttt
     5041 gagaaggagc aacattgccg tatttatcat tttccatcaa accatcaata acatttccaa
     5101 taacgtctgt cgtcgatgtt cgagtcgtta tactgtagcc caatgatgct ggatctactg
     5161 catagacata agaaaatgtt gtcggtgcat ctgcttcttt atcagttttt ccacaagcca
     5221 ctaaaatagc taacgtgctc aggaccactc ctgctgttaa gagccacttt ttctatttca
     5281 taaaaaatct cctttggttt attttaatct acttttacaa tccaaccttc tggcgcttca
     5341 atatcgccaa actgaatacc cgtcaattca ttatataatt tacgcgtcac aggacctact
     5401 tctgtttcac tatagaatac atggaaatca tcaccatgtt gaatacctcc aattggagaa
     5461 ataaccgctg ctgtaccaca ggcacctgcc tctacaaaac ggtcaagatt atcaattgga
     5521 acatcaccct caataggagt taatcccaag cgatgttctg ccaaataaag caaggaatac
     5581 ttggtaatag atggcaagat agatggactc aatggtgtta caaattcatt atcagctgta
     5641 attccaaaga aattagctga tccgacttct tcaatctttg tatgagttga tgggtccaga
     5701 tagataacat ctgagaaatg gcgtgacttg gccatttttc ctggtaagag acttgcagca
     5761 tagtttccac caaccttagc cgcacctgta ccatttggtg ctgcacggtc gtactcatcc
     5821 tgaatcaaga agttggttgg gaccaaacca cctttaaagt aatttccaac tggcatagca
     5881 aagatggtga aaatgtactc ttctgccggt tttaccccga taatatctcc gacaccaatc
     5941 aaaagagggc gaagatataa ggttccacct attccgtatg gtggtacgta ttcttcattc
     6001 gcacggacaa ctgctttaca agcttctaca aacatgtctg tcggaacttg tggcatcaag
     6061 agacggtcac atgtacgttg caggcgttta gcattttcat caggacggaa cagttgaaca
     6121 ctgccatcct tagtacgata agctttcaaa ccttcaaatg cttgttgtcc atagtgaaga
     6181 cttggagaag actctgaaat atgcaaagtt gcatcctctg taagctctcc ttgatcccat
     6241 tgtccatttt tgaaatgagc aagatagcga taaggtaatt tcatatagga aaaaccgagg
     6301 ttttcccaat caatcgttac tgtcatattc cactccttat tctaaaaacc tatttcttat
     6361 attctacact atttttctaa aatagcaagt atattttgta attttcagaa aattcctcca
     6421 ataaaaacca tcttagaact gattcttcat ttcacttatt tatcttcagt aactacttcc
     6481 tgaagataag cgtcaaaaac ttcttcatct gaaatcgtgt cagaaatgaa gcttccattg
     6541 ctagtgcgtt ctgacaagtt caagtcttgc aatcggcttt catagattgt tcctttattg
     6601 gattggacaa gcagagtttg gtcgttcaca tccacttccg tactgaagaa atcgccaaca
     6661 aatccttgct ctgcaactgc tcctgccaag aagacacgat gcggtttgtt tttcaactca
     6721 cgcaagactt gtaatcctcg tttggcacgg ctggttgcta gaatttcctc aatggaaaca
     6781 cgtttcaagc ttccacgctg ggtcaagagg tagaaggacg aagtattaca gataaagcca
     6841 gattggagga catcatcttc tttcaaattc atagccttga cacctgctgc cttagcaccg
     6901 acaaccggaa cctcttcgat attgaaacgc agggcataac cattttgact aaccaagaca
     6961 acatcatcta gtttaatcgg agccactgct acaatctgat ctgtatcgtc tttgagctta
     7021 gcatacttga cagacttaga tctataggtc cgccatggag tgaattcttt tcgctctacc
     7081 cgtttgattt gaccaaggcg agtcgctgca aagtaggttg tcgcatcgtc aaactgatcc
     7141 agtacttcca cataaaggat tgcttcattc gtttcaaagt ttgtgatggt ttggctcaga
     7201 tgctctccga tgtccttcca acgaatatct gccaactcat ggattggtct gtagatgaca
     7261 tttccaagac ttgtgaacat caagaggtgc tgggttgtct tggcagattg aacaaaaatc
     7321 aaacggtcat catcacgctt gccaatttct tccaaggtgg aagccgcaaa ggaacgtgga
     7381 ctggtacgct tgatgtaacc tgccttggtc acgctgacgt aggtatcttc ctcagcgata
     7441 agactagctg tatcaatctc aattgctttc gcagtgtctt ctaaagaact caaacgagga
     7501 gttgcaaagt tcttcttgac ctcacgaagt tctttcttca tgagattgta catagtcctt
     7561 tcatcaccga taatagccgc cagcatagca atcttctcac gaagctctgc ttcttcttcc
     7621 tgcaagacaa ccacatcggt attggtcaaa cggtacagtt gcaaagttac gatagcctca
     7681 gcctgttctt ccgtaaaatc atagctaact ttgaggtttt ccttggcgtc cgccttattc
     7741 tcagaagcac ggataagagc aatgacttca tccaaaatcg aaatcacacg aatcaaacct
     7801 tcgacgatac ggagacgttt ctcagccttt tctttgtcaa agcgtgaacg cgccaaaatc
     7861 acttctcgac ggtgagcgat gtagctagac aggattggaa caatcccaac ctgacgaggt
     7921 gtgaaattgt caatcgccac catattaaag ttgtagttga tttgtaggtc ggtgtactta
     7981 aataagtagt tgagaacaag ctcagtatta gcgtctttct taagttcaat agcgatacga
     8041 agaccatcac ggtcagactc atcacgaacc tcagcaatcc cagctacctt gttattaaca
     8101 cgaacatcat cgattttctt gactagattg gccttattga tttcataagg aatctcagta
     8161 ataacgattt gttccttacc accttttagc ttttcaattt cagtcttgga acgaacaacc
     8221 acgcgccctt tcccagtctc ataggctttc ttgatttcat cacgaccctg aataatagcc
     8281 cctgtaggga agtctggtcc aggtaagaat tccatgagtt tatcaatctt tgcagttggg
     8341 tggtcaatca tgtaaactgc agcatctatg acctcagcta aattatgggg aggaatgtct
     8401 gtggcataac cagccgaaat cccagtcgaa ccattgacca agaggtttgg aaaggctgct
     8461 ggcaagaccg ttggttcttt ctccgtatcg tcaaagttcc atgcaaaagg aactgtcttt
     8521 ttctcgatat cctgaagaag gtagcctgca atttcagaca aacgtgcctc agtataacgc
     8581 atagccgcag gaggatctcc gtccatagaa ccgttattac cgtgcatttc aactagaatc
     8641 tcacgatttt tccagttctg tgacatacga accatggcat catagataga agaatccccg
     8701 tgtgggtgga aattccccat gatgttcccg actgacttgg ccgacttacg gtagctcttg
     8761 tcaaaagtat tgctatcctt attcatagaa taaagaatac ggcgttgaac cggcttcaac
     8821 ccatcacgaa tatctggcaa agcccggtct tgaataatgt acttggagta gcgaccaaag
     8881 cgctctccca tgatgtcctc cagggacatg ttttgaatgt tagacataag atacaaagcc
     8941 cataaaatac caagtgaaaa tagaaaattc ttgaagtaag caaactcaca agagaattta
     9001 tctttttcac acagtatcta gggcgtgttc aactcctttc aaagaatgta gagtaggttt
     9061 ttatgcagta aaagatattt tacgggaatt cgtcccgtgt tcagttacga taagtaacca
     9121 aactatcctg tttgtatttt tcaatatgaa aatctggttt tccaaaatta gtcttagttt
     9181 gtgtcttaac cgctccctta agcgcctctt taagataagc actcatagca gattcttcat
     9241 taataatcct gcaatttttt caaaccaaga ttttcaaact gctttttcac atagtcattc
     9301 acatccgact ctaatttcca gtttactaac atattatttt ctttcattaa aacactgtcg
     9361 cttcttctag cgtaaacttg acattatctt caatccattt acggcgtggt tctaccttat
     9421 ctcccatgag aacattgacg cggcgttcgg cgcgcgctaa atcttcaatt gtgacacgga
     9481 tgagggtacg tgtttctggg ttcatggttg tttcccagag ctggtccgca ttcatctcac
     9541 caagtccttt gtatcgttgg agggtagcgc ctttaccgaa ctgtttacgg agttcttcta
     9601 gttctccgtc cgtccaagcg taggccactt cttctttctt gcctttacct ttggacatct
     9661 tgtaaagagg tgggagggca atatagacat gacctgcctc gactagcgga cgcatgtaac
     9721 ggtagaaaaa tgtcaagagc aaggtctgga tatgggcacc gtcggtatcc gcatcggtca
     9781 tgataatgat cttatcatag ttggcatctt caatagagaa gtctgctcca acacccgcac
     9841 caatggtata aatcatggta ttgatctctt catttttgag gatatccgcc atcttggcct
     9901 tggctgtatt gataacctta ccacgaagag gtagaatagc ctggaacttg cggtcacgac
     9961 cttgtttggc agaaccaccg gcagagtccc cctcaactag atagagttca ttcttagcag
    10021 gattcttaga ttgggctggg gtcaatttcc cagacaacaa gcccttatct ttcttgtttt
    10081 tcttcccatt tcggctctca tcacgcgcct tacgtgctgc ttcacgagca tcacgggcct
    10141 tgatagcctt gcggatgagg ttagaagcta attccccatt ttccataagg aaaaaggtca
    10201 acttatcagc cactattcca tccacaactg ggcgagctag ggggcttcct agtttatcct
    10261 tggtctgtcc ttcaaactgc aagtgttctt caggaactaa gatagaaaga acggccgcta
    10321 gtccctcacg atagtctgaa ccttcaaggt ttttatcttt ttccttgaga agacctgttt
    10381 tacgtgcata gtcattcatg accttggtaa tggcagactt gagtcctgtc tcgtgcgttc
    10441 caccgtcctt ggtgcgaacg ttattgacaa aggatagaat gttatctgag aatccgtcat
    10501 tgtactggag ggctacttcc acttgaaaac cattgtcttc cccttcaaag taaagaactg
    10561 gcgtcaagat ttccttatct tcgttgagat aagaaacaaa atcttgtact ccattctcat
    10621 agtggaactc aatcgcttca tctgttcgct tgtccgttaa agacaaggtc acatttttca
    10681 agagaaaggc tgattcatta aggcgctctg aaatggtatt gtacttgaaa tctgtcgtag
    10741 aaaagatagt cgcgtcaggc ataaaagtaa ctttggtgcc tgttttagac ttgagtgctg
    10801 taccgatttt cttcaaagtc gtgacaggtt ttccaccatt ttcaaaacgt tgcttgtaaa
    10861 ctgcgccatc acgggtaatt tcaacttcta accagctaga aagggcgtta acaacggaag
    10921 aacccactcc gtgaagtcca cctgatgtct tatagccacc ttgaccgaat ttccctccgg
    10981 catgaagaat ggtaaagata acctcaacag ttggaattcc catagcgtgc atacctgtcg
    11041 gcatcccacg tccatggtct tgaaccgtta gactaccgtc tttattgata gttacatcaa
    11101 tacgatcacc aaacccagac aaggcttcat cgactgcatt atcaacgatt tcccaaacta
    11161 ggtgatgaag accagcgcca tcggtcgatc caatatacat ccctggacgt tttcggaccg
    11221 catccaaccc ttctagcacc tgaatagcat catcattata attgttaata ttgatttcct
    11281 tttttgacac aaggaacctc ctattcgttc atctttacta ttctacaggt tttccaagga
    11341 ttttgcaaaa tttttctttc tccgatgtga caatttcagc agagattctc tgcttttctt
    11401 tcccaattca tgatataata ggagtatgat tacaatagtt ttattaatcc tagcctatct
    11461 gctgggttcg attccatctg gtctctggat tggacaagta ttctttcaaa tcaatctacg
    11521 cgagcatggt tctggtaaca ctggaacgac caacaccttc cgcattttag gtaagaaagc
    11581 tggtatggca acctttgtga ttgacttttt caaaggaacc ctagcaacgc tgcttccgat
    11641 tatttttcat ctacaaggcg tttctcctct catctttgga cttttggctg ttatcggcca
    11701 taccttccct atctttgcag gatttaaagg tggtaaggct gtcgcaacca gtgctggagt
    11761 gattttcgga tttgcgccta tcttctgtct ctaccttgcg attatcttct ttggagctct
    11821 ctatcttggc agtatgattt cactgtctag tgtcacagca tcgatcgcgg ctgttatcgg
    11881 ggttctgctc tttccacttt ttggttttat cctgagtaac tatgactctc tcttcatcgc
    11941 tattatctta gcacttgcta gtttgattat cattcgtcat aaggacaata tagctcgtat
    12001 caaaaataaa actgaaaatt tggtcccttg gggattgaac ctaacccatc aagatcctaa
    12061 aaaataaaac gccagttctg tactgccccc aaacagttag acaaataatt tatccaaagg
    12121 atttagttct gtattgcaca gggctaagtc cttttagttt taccttaatt cgtttgttgt
    12181 tgtagtaatc aatatagtct ataatggctt gttccaattg gttaagtgat ttaaatgttt
    12241 tctcatagcc ataaaacatt tcggatttca gaatcccaaa gaaggactcc atcataccgt
    12301 tgtcttggct gtttcccttg cgtgacatag atgcttgaat tcccttactc tctaggaacc
    12361 gatgataaga atcgtgttga tattgccagc cttggtcact atggagaatc gtattctcgt
    12421 agtgcttctc tttgaatgcc tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag
    12481 ttgaaagatt ataggcgata atttcgctat taaagccatc taaaactggt gataagtaaa
    12541 gcttttgagt acttactgga atggcaaatt cagtcacatc tgtgtagcac tgttccattg
    12601 ttttagagcc ttcaaattgg ccttgaatga gattctctgc tttcttgcca acgtctcctt
    12661 tatgagaaga atattttcgt ttctgtcgcg ttttagcttg taaattgagt acttcatcaa
    12721 gtgttgaact cttttatgat ttaccagata accacgattt cttagttcta aataaatccg
    12781 acgataagca taatttccct tgtgttcgat aaagatggat tgaatttcag ctttaagctc
    12841 ttggtcctta tctgttttgt ctagctgttt caagtgatag tagtaggtcg aacgagctag
    12901 tttaatggct tttagaagaa ga
//
LOCUS       DAVLHM010000051        12613 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLHM010000051 DAVLHM010000000
VERSION     DAVLHM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.051"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            10..1146
                     /gene="dnaN"
                     /locus_tag="VXE45_001794"
     CDS             10..1146
                     /gene="dnaN"
                     /locus_tag="VXE45_001794"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0789790.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTIKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            1211..1405
                     /locus_tag="VXE45_001795"
     CDS             1211..1405
                     /locus_tag="VXE45_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0789791.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1489..2604
                     /gene="ychF"
                     /locus_tag="VXE45_001796"
     CDS             1489..2604
                     /gene="ychF"
                     /locus_tag="VXE45_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0789792.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2675..3244
                     /locus_tag="VXE45_001797"
     CDS             2675..3244
                     /locus_tag="VXE45_001797"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0789793.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3245..6751
                     /gene="mfd"
                     /locus_tag="VXE45_001798"
     CDS             3245..6751
                     /gene="mfd"
                     /locus_tag="VXE45_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0789794.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDQDAFDDAFPYVETDDQLRSIEEIK
                     RDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFKE
                     RFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMIID
                     EEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGRM
                     SEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLGK
                     SQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQR
                     HKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRVE
                     RKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEIL
                     EGLLIFGESLLEIKESKEENSI"
     gene            6809..7075
                     /locus_tag="VXE45_001799"
     CDS             6809..7075
                     /locus_tag="VXE45_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0789795.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7068..7436
                     /locus_tag="VXE45_001800"
     CDS             7068..7436
                     /locus_tag="VXE45_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0789796.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGVVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7556..8824
                     /locus_tag="VXE45_001801"
     CDS             7556..8824
                     /locus_tag="VXE45_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0789797.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8821..10098
                     /gene="tilS"
                     /locus_tag="VXE45_001802"
     CDS             8821..10098
                     /gene="tilS"
                     /locus_tag="VXE45_001802"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0789798.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10102..10644
                     /gene="hpt"
                     /locus_tag="VXE45_001803"
     CDS             10102..10644
                     /gene="hpt"
                     /locus_tag="VXE45_001803"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0789799.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10660..>12613
                     /gene="ftsH"
                     /locus_tag="VXE45_001804"
     CDS             10660..>12613
                     /gene="ftsH"
                     /locus_tag="VXE45_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0789800.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         4343 a         1902 c         2562 g         3806 t
ORIGIN      
        1 ggagaatcca tgattcattt ttcaattaat aaaaatttat ttctacaagc attaaatact
       61 actaagagag ctattagttc taaaaatgcc attcctattt tatcaacaat aaaaattgac
      121 gtgaccaatg aaggtattac tttaattggt tcaaatggtc aaatttcaat tgaaaatttt
      181 atttctcaaa aaaatgaaga tgctggtttg ttaattactt ctttaggttc gatccttctt
      241 gaagcttctt tctttatcaa tgtagtatct agtttacctg atgtaactct tgattttaaa
      301 gaaattgaac aaaatcaaat tgttttaacc agtggcaaat cagaaattac cctaaaagga
      361 aaagatagcg aacaatatcc acgaatccaa gaaatttcag caagcactcc tttaatactt
      421 gaaacaaaat tactcaagaa aattattaat gaaacagcct ttgctgcaag tacacaagag
      481 agtcgtccga ttttaacagg tgtccacttc gtattgagtc aacacaaaga gttaaaaaca
      541 gttgcaacag actctcatcg cctaagccag aaaaaattga ctcttgaaaa aaatagtgat
      601 gattttgatg tcgtaattcc tagccgttct ctacgcgaat tttcagcggt atttacagat
      661 gatatcgaaa ctgtagagat tttctttgcc aataaccaaa tcctctttag aagcgaaaat
      721 attagcttct atactcgtct cctagaagga aactatcctg atacagatcg cttgattcca
      781 acagacttta acactactat tacttttaat gtggtaaact tacgccagtc aatggagcgt
      841 gcccgtcttt tatcaagtgc gactcaaaat ggtactgtga aacttgaaat taaggatggg
      901 gttgttagcg cccatgttca ctctccagaa gttggtaaag taaacgaaga aatcgatact
      961 gatcaggtta ctggtgaaga tttgaccatt agtttcaacc caacttactt gattgattct
     1021 cttaaagctt taaatagcga aaaggtgacc attagcttta tctcagctgt tcgtccattt
     1081 actcttgtgc cagcagatac tgacgaagac ttcatgcagc tcattacacc agttcgtaca
     1141 aattaagtga aagaggttga gcctggctcg cctcttttat gatataatcg aaaaagaaaa
     1201 ggagagtagt atgtatcaag ttggaaattt tgttgagatg aaaaaatcac acgcttgtac
     1261 aatcaagtcg actggtaaaa aggctaatcg ttgggaaatt acacgtgtag gagcagatat
     1321 caaaataaaa tgcagtaatt gtgagcatgt tgtcatgatg gggcgatatg attttgagcg
     1381 aaaaatgaat aaaattattg actgagaacc cttagttaga gggttagcac tttatccctt
     1441 tttgtgttat aatattaggg attgaaatga aaacggagaa tgagaaatat ggctttgaca
     1501 gcaggtatcg ttggtttgcc aaacgttggt aaatcaacac tatttaatgc aattacaaaa
     1561 gcaggagcag aggcagcaaa ctacccattt gcgactattg atccaaatgt tggaatggtg
     1621 gaagttccag atgaacgcct acaaaaacta actgaaatga taactcctaa aaagacagtt
     1681 cccacaacat ttgaatttac ggatattgca gggattgtaa aaggagcttc aaaaggagaa
     1741 gggctaggga ataaattctt ggccaatatt cgtgaagtag atgcgattgt tcacgtagtt
     1801 cgtgcttttg atgatgaaaa tgtgatgcgc gagcaaggac gtgaagacgc ctttgtggat
     1861 ccacttgcag atattgacac cattaaccta gaattgattc ttgcagactt agaatcagtc
     1921 aataaacgat atgcgcgtgt agaaaagatg gcacgtacgc aaaaagataa agaatcagta
     1981 gcagaattca atgttcttca aaagattaaa ccagtcctag aagacgggaa atcagctcgt
     2041 accattgaat ttacagatga ggaacaaaag gttgtcaaag gtcttttcct tttgacgact
     2101 aaaccagttc tttatgtagc taatgtggac gaggatgtgg tttcagaacc tgactctatc
     2161 gactatgtca aacaaattcg tgaatttgca gcgacagaaa atgctgaagt agtcgttatt
     2221 tctgcgcgtg ctgaggaaga aatttctgaa ttggatgatg aagataaaaa agagtttctt
     2281 gaagccattg gtttgataga atcaggtgta gataagttga cgcgtgcagc ttaccacttg
     2341 cttggattgg gaacttactt cacagctggt gaaaaagaag ttcgcgcttg gactttcaaa
     2401 cgtggtatga aggctcctca agcagctggt attatccact cagactttga aaaaggcttt
     2461 attcgtgcag taaccatgtc atatgaggat ctagtgaaat acgaatctga aaaggccgta
     2521 aaagaagctg gacgcttgcg tgaagaagga aaagaatata tcgttcaaga tggcgatatc
     2581 atggaattcc gctttaatgt ctaaaaatta ataaatggtg tcaattaggt tggaaaaaaa
     2641 ttccaaccct tttggctttt gaaaggaaaa ataaatgacc aaattacttg taggcttggg
     2701 aaatccaggg gataaatatt ttgaaacaaa acacaatgtt ggttttatgt tgattgatca
     2761 actagcgaag aaacagaatg tcacttttac acacgataag atatttaaag ctgacctagc
     2821 atcctttttc ctaaatggag aaaaaattta tctggttaaa ccaacgacct ttatgaatga
     2881 aagtggaaaa gcagttcatg ctttattaac ttactatggt ttggatattg acgatttact
     2941 tatcatttac gatgatcttg acatggaagt tgggaaaatt cgtttaagag caaaaggctc
     3001 agcaggtggt cataatggta tcaagtctat tattcaacat ataggaactc aggtctttaa
     3061 ccgtgttaag attggaattg gaagacctaa aaatggtatg tcagttgttc atcatgtttt
     3121 gagtaagttt gacagggatg attatatcgg tattttacag tctgttgaca aagttgacga
     3181 ttctgtaaac tactatttac aagagaaaaa ttttgagaaa acaatgcaga ggtataacgg
     3241 ataaatggtg accttattag atttattctc agaaaatgat cagattaaaa aatggcatca
     3301 aaatttaact gataagaaaa gacaactaat acttggttta tcaacatcta ctaaggctct
     3361 tgcaattgca agcagtttag aaaaagaaga taggattgtg ttattgacgt caacttatgg
     3421 agaagcagaa ggacttgtta gtgatcttat atctatcttg ggtgaggaac tcgtctatcc
     3481 atttttggta gatgatgctc ctatggtgga gtttttgatg tcttcacagg aaaaaattat
     3541 ttcacgggtt gaagccttgc gttttttgac tgattcatct aagaaaggga ttttagtttg
     3601 taatatcgca gcaagtcgat tgattttacc gtctcccaat gcattcaaag atagtattgt
     3661 aaaaatctca gttggtgaag aatatgatca acacgcgttt atccatcagt taaaggaaaa
     3721 tggctatcga aaagttactc aagtacaaac tcagggcgaa tttagtcttc gaggagatat
     3781 tttagatatt tttgaaatat cccagttaga accttgtcga attgagtttt ttggtgatga
     3841 aattgatggt atcaggtcat ttgaagtaga aacacaatta tcgaaagaaa ataagacaga
     3901 actcactatc tttccagcta gtgatatgct tttgagagaa aaggattatc aacgaggaca
     3961 gtcagcttta gaaaaacaaa tttcaaaaac tttatcacct attttgaaat catacctaga
     4021 agaaattctt tcaagttttc accaaaaaca aagtcatgca gactctcgga agtttttatc
     4081 tttgtgctat gataagacat ggactgtctt tgattatatt gaaaaagata ctccaatatt
     4141 ctttgatgat tatcaaaaat tgatgaatca gtatgaagtc tttgaaagag acttagcgca
     4201 gtactttaca gaagaattac agaatagtaa agcattttct gatatgcagt atttttctga
     4261 tattgaacaa atctataaaa aacaaagtcc agtgaccttt ttctctaatc ttcaaaaggg
     4321 tttaggaaat ctcaaatttg acaaaattta tcaattcaat caatatccta tgcaggaatt
     4381 tttcaatcag ttttcttttc taaaagaaga aattgaacga tataaaaaaa tggattacac
     4441 cattattctg cagtctagca attcaatggg aagtaaaaca ttggaggata tgttagagga
     4501 atatcagatt aaattggatt ctagagataa gacaaatatc tgtaaagaat ctgtaaactt
     4561 aatagagggt aatctcagac atggttttca ttttgtagat gaaaagattt tattgataac
     4621 tgaacatgag atttttcaaa agaaattaaa gcgtcgtttt cgaagacaac atgtttcaaa
     4681 tgcagagaga ttaaaagatt acaatgaact tgaaaaaggg gactatgttg tccatcatat
     4741 ccatgggatt ggtcaatatc taggaattga aaccattgaa atcaagggaa ttcatcgcga
     4801 ttatgtcagt gtccaatacc aaaatggtga tcaaatttct atccccgtgg aacagattca
     4861 tctactgtcc aaatatattt caagtgatgg taaagctcca aaactcaata aattaaatga
     4921 cggtcatttt aaaaaggcca agcaaaaggt taagaaccag gtagaggata tagctgatga
     4981 tttaatcaaa ctctactctg aacgtagtca gttgaagggt tttgctttct cagctgatga
     5041 tgatcaagat gcctttgatg atgctttccc ttatgttgaa acggatgatc aacttcgtag
     5101 tattgaggaa atcaaaaggg atatgcaggc ttctcagcca atggatcgac ttttagttgg
     5161 ggatgttggt tttggaaaga ctgaagttgc tatgcgtgca gcctttaaag cagtcaatga
     5221 tcacaaacag gttgtcattc tagttccgac gacggtttta gcgcaacagc actatacgaa
     5281 ttttaaggaa cgattccaaa attttgcagt taatgttgat gtgttgagtc gctttagaag
     5341 taaaaaagag cagactgcaa cacttgaaaa attgaaaaac ggtcaagtcg atattttgat
     5401 tggaacacat cgtgttttgt caaaagatgt tgtgtttgct gatttgggct tgatgattat
     5461 tgatgaggaa cagcgatttg gtgtcaagca taaggaaact ttgaaagaac tgaagaaaca
     5521 agtggatgtc ctaaccttga ccgctacgcc aatccctcgt accctccata tgtctatgct
     5581 gggaatcaga gatttgtctg ttattgaaac tccgccgact aatcgctatc ctgttcagac
     5641 ctatgttttg gaaaagaatg atagtgtcat tcgtgatgct gtcttgcgtg aaatggagcg
     5701 tggaggtcaa gtttactatc tttacaacaa agttgacaca attgttcaga aggtttcaga
     5761 attacaggag ttgattccgg aggcttcgat tggatatgtt catggtcgaa tgagtgaagt
     5821 ccagttggaa aatactctat tagactttat tgagggacaa tacgatatct tggtgacgac
     5881 tactattatt gagacagggg tggacattcc aaatgctaat actttattta ttgaaaatgc
     5941 ggaccatatg ggcttgtcaa ccttatatca gttaagagga agagtcggtc gtagtaatcg
     6001 tattgcttat gcttatctca tgtatcgtcc agaaaaatca atcagtgaag tctctgaaaa
     6061 gagattagaa gcgattaaag gatttacaga attgggctct ggctttaaga ttgcaatgcg
     6121 agatctttcg attcgtggag caggaaatct tttaggaaaa tcccagtctg gtttcattga
     6181 ttctgttggt tttgaattgt attcgcagtt attagaggaa gctattgcta aacgaaacgg
     6241 taatgctaac gctaacacaa gaaccaaagg gaatgctgag ttgattttgc aaattgatgc
     6301 ctatcttcct gatacttata tttctgatca acgacataag attgaaattt acaagaaaat
     6361 tcgtcaaatt gacaaccgtg tcaattatga agagttacaa gaggagttga tagaccgttt
     6421 tggagaatac ccagatgtag tagcctatct tttagagatt ggtttggtca aatcatactt
     6481 ggacaaggtc tttgttcaac gtgtggaaag aaaagataat aaaattacaa ttcaatttga
     6541 aaaagtcact caacgactgt ttttagctca agattatttt aaagctttat ccgtaacgaa
     6601 cttaaaagca ggcatcgctg agaataagga attaatggag cttgtatttg atgttcaaaa
     6661 taagaaagat tatgaaattt tagaaggtct gctgattttt ggagaaagtt tattagagat
     6721 aaaagagtct aaggaagaaa attccatttg atatttttct tctataaaat agataaaaat
     6781 ggtacaataa taaattgagg taataaggat gagattagat aaatatttaa aagtatcgcg
     6841 aattatcaag cgtcgtacag tcgcaaagga agtagcagat aaaggtagaa tcaaggttaa
     6901 tggaatcttg gccaaaagtt caacggactt gaaagttaat gaccaagttg aaattcgctt
     6961 tggcaataag ttgctgcttg taaaagtact agagatgaaa gatagtacaa aaaaagaaga
     7021 tgcagcagga atgtatgaaa ttatcagtga aacacgggta gaagaaaatg tctaaaaata
     7081 ttgtacaatt gaataattct tttattcaaa atgaatacca acgtcgtcgc tacctgatga
     7141 aagaacgaca aaaacggaat cgttttatgg gagtggtatt gattttgatt atgctattat
     7201 ttatcttgcc aacttttaat ttagcgcaga gttatcagca attactccaa agacgtcagc
     7261 aattagcaga cttgcaaact cagtatcaaa ctttgagtga tgaaaaggat aaggagacag
     7321 catttgctac caagttgaaa gatgaagatt atgctgctaa atatacacga gcgaagtact
     7381 attattctaa gtcgagggaa aaagtttata cgattcctga cttgcttcaa aggtgataaa
     7441 atggaaaatt tattagacgt aatagagcaa tttttgagtt tgtcagatga aaagctggaa
     7501 gaattggctg ataaaaatca attattgcgt ttacaagaag aaaaggaaag gaagaatgcg
     7561 taaattctta attattttgt tgctaccaag ttttttgacc atttcaaaag tcgttagcac
     7621 agaaaaagaa gtcgtctata cttcgaaaga aatttattac ctttcacaat ctgactttgg
     7681 tatttatttt agagaaaaat taagttctcc catggtttat ggagaggttc ctgtttatgc
     7741 gaatgaagat ttagtagtgg aatctgggaa attgactccc aaaataagtt ttcaaataac
     7801 cgagtggcgc ttaaataaac aaggaattcc agtatttaag ctatcaaatc atcaatttat
     7861 agctgcggac aaacgatttt tatatgatca atcagaggta actccaacaa taaaaaaagt
     7921 atggttagaa tctgacttta aactgtacaa tagtccttat gatttaaaag aagtgaaatc
     7981 atccttatca gcttattcgc aagtatcaat cgacaagacc atgtttgtag aaggaagaga
     8041 atttctacat attgatcagg ctggatgggt agctaaagaa tcaacttctg aagaagataa
     8101 tcggatgagt aaagttcaag aaatgttatc tgaaaaatat cagaaagatt ctttctctat
     8161 ttatgttaag caactgacta ctggaaaaga agctggtatc aatcaagatg aaaagatgta
     8221 tgcagccagc gttttgaaac tctcctatct ctattatacg caagaaaaaa taaatgaggg
     8281 tctttatcag ttagatacga ctgtaaaata cgtatctgca gtcaatgatt ttccaggttc
     8341 ttataaacca gagggaagtg gtagtcttcc taaaaaagaa gataataaag aatattcttt
     8401 aaaggattta attacgaaag tatcaaaaga atctgataat gtagctcata atctattggg
     8461 atattacatt tcaaaccaat ctgatgccac attcaaatcc aaaatgtctg ccattatggg
     8521 agatgattgg gatccaaaag aaaaattgat ttcttctaag atggccggga agtttatgga
     8581 agctatttat aatcaaaatg gatttgtgct agagtctttg actaaaacag attttgatag
     8641 tcagcgaatt gccaaaggtg tttctgttaa agtagctcat aaaattggag atgcggatga
     8701 atttaagcat gatacgggtg ttgtctatgc agattctcca tttattcttt ctattttcac
     8761 taagaattct gattatgata cgatttctaa gatagccaag gatgtttatg aggttctaaa
     8821 atgagggaac aagatttttt aaatcatttt ctcaagaagg gatatttcaa aaagcatgct
     8881 aaggcggttc tagctctttc tggtggatta gattctatgt ttctatttaa ggtattgtct
     8941 acttatcaaa aagagttaga gattgaattg attctggctc atgtgaatca taagcagaga
     9001 attgaatcag attgggaaga aaaggaatta aggaagttgg ctgctgaagc agaacttcct
     9061 atttatatca gcaatttttc aggagaattt tcagaagcgc gtgcacgaaa ttttcgttat
     9121 gatttttttc aagaggtcat gaaaaagaca ggtgcgacag ctttagtcac tgcccaccat
     9181 gctgatgatc aggtggaaac gattttgatg cgcttgattc gaggaactcg cttgcgctat
     9241 ctatcaggaa ttaaggagaa gcaagtagtc ggagagatag aaatcattcg tcccttcttg
     9301 cattttcaga aaaaagactt tccatcaatt tttcactttg aagatacatc aaatcaggag
     9361 aatcattatt ttcgaaatcg tattcgaaac tcttacttac cagaattgga aaaagaaaat
     9421 cctcgattta gggatgcaat cttaggcatc ggcaatgaaa ttttagatta tgatttggca
     9481 atagctgaat tatctaacaa tattgatgtg gaaaatttac agcagttatt ttcttactct
     9541 gagtctacac aaagagtttt acttcaaact tatctgaatc gttttccaga tttgaatctt
     9601 acaaaagctc agtttgctga agttcagcag attttaaaat ctaaaagcca gtatcgtcat
     9661 ccgattaaaa atggctatga attgataaaa gagtaccaac agtttcagat ttgtaaaatc
     9721 agtccgcagg ctgatgaaaa ggaagatgaa cttgtgttac actatcaaaa tcaggtagct
     9781 tatcaaggat atttattttc ttttggactt ccattagaag gtgaattaat tcaacaaata
     9841 cctgtttcac gtgaaacatc catacacatt cgtcatcgaa aaacaggaga tgttttgatt
     9901 caaaatgggc atagaaaaaa actcagacgt ttatttattg atttgaaaat ccctatggaa
     9961 aagagaaact ctgctcttat tattgagcaa tttggtgaaa ttgtctcaat tttgggaatt
    10021 gcgaccaata atttgagtaa aaaaacgaaa aatgatataa tgaacactgt actttatata
    10081 gaaaaaatag ataggtaaaa aatgttagaa aacgatatta aaaaagtcct cgtttcacac
    10141 gatgaaatta cagaagcagc taaaaaacta ggtgctcaat taactaaaga ctatgcagga
    10201 aaaaatccaa tcttagttgg gattttaaaa ggatctattc cttttatggc tgaattggtc
    10261 aaacatattg atacacatat tgaaatggac ttcatgatgg tttctagcta ccatggtgga
    10321 acagcaagta gtggtgttat caatattaaa caagatgtga ctcaagatat caaaggaaga
    10381 catgttctat ttgtagaaga tatcattgat acaggtcaaa ctttgaagaa tttgcgagat
    10441 atgtttaaag aaagagaagc agcttctgtt aaaattgcaa ccttgttgga taaaccagaa
    10501 ggacgtgttg tagaaattga ggcagactat acctgcttta ctatcccaaa tgagtttgta
    10561 gtaggttatg gtttagacta caaagaaaat tatcgtaatc ttccttatat tggagtattg
    10621 aaagaggaag tgtattcaaa ttagaaagaa taatctttaa tgaaaaaaca aaataatggt
    10681 ttaattaaaa atccttttct atggttatta tttatctttt tccttgtgac aggattccag
    10741 tatttctatt ctgggaataa ctcaggagga agtcagcaaa tcaactatac tgagttggta
    10801 caagaaatta ccgatggtaa tgtaaaagaa ttaacttacc aaccaaatgg tagtgttatc
    10861 gaagtttctg gtgtctataa aaatcctaaa acaagtaaag aaggaacagg tattcagttt
    10921 ttcacgccat ctgttactaa ggtagagaaa tttaccagca ctattcttcc tgcagatact
    10981 accgtatcag aattgcaaaa acttgctact gaccataaag cagaagtaac tgttaagcat
    11041 gaaagttcaa gtggtatatg gattaatcta ctcgtatcca ttgtgccatt tggaattcta
    11101 ttcttcttcc tattctctat gatgggaaat atgggaggag gcaatggccg taatccaatg
    11161 agttttggac gtagtaaggc taaagcagca aataaagaag atattaaagt aagattttca
    11221 gatgttgctg gagctgagga agaaaaacaa gaactagttg aagttgttga gttcttaaaa
    11281 gatccaaaac gattcacaaa acttggagcc cgtattccag caggtgttct tttggaggga
    11341 cctccgggga caggtaagac tttgcttgct aaggcagtcg ctggagaagc aggtgttcca
    11401 ttctttagta tctcaggttc tgactttgta gaaatgtttg tcggagttgg agctagtcgt
    11461 gttcgctctc tttttgagga tgccaaaaaa gcagcaccag ctatcatctt tatcgatgaa
    11521 attgatgctg ttggacgtca acgtggagtt ggtctcggcg gaggtaatga cgaacgtgaa
    11581 caaaccttga accaactttt gattgagatg gatggttttg agggaaatga agggattatc
    11641 gtcatcgctg cgacaaaccg ttcagatgta cttgatcctg cccttttgcg tccaggacgt
    11701 tttgatagaa aagtattggt tggccgtcct gatgttaaag gtcgtgaagc aatcttgaaa
    11761 gttcacgcta agaacaagcc tttagcagaa gatgttgatt tgaaattagt ggctcaacaa
    11821 actccaggct ttgttggtgc tgatttagag aatgtcttga atgaagcagc tttagttgct
    11881 gctcgtcgca ataaatcgat aattgatgct tcagatattg atgaagcaga agatagagtt
    11941 attgctggac cttctaagaa agataagaca gtttcacaaa aagaacgaga attggttgct
    12001 taccatgagg caggacatac cattgttggt ctagtcttgt cgaatgctcg cgttgtccat
    12061 aaggttacaa ttgtaccacg cggccgtgca ggcggataca tgattgcact tcctaaagag
    12121 gatcaaatgc ttctatctaa agaagatatg aaagagcaat tggctggctt aatgggtgga
    12181 cgtgtagctg aagaaattat ctttaatgtc caaactacag gagcttcaaa cgactttgaa
    12241 caagcgacac aaatggcacg tgcaatggtt acagagtacg gtatgagtga aaaacttggc
    12301 ccagtacaat atgaaggaaa ccatgctatg tttggtgcac agaatcctca aaaatcaatt
    12361 tcagaacaaa cagcttatga aattgatgaa gaggttcgtt cattattaaa tgaggcacga
    12421 aataaagctg ctgaaattat tcagtcaaat cgtgaaactc acaagttaat tgcagaagca
    12481 ttattgaaat acgaaacatt ggatagtaca caaattaaag ctctttacga aacaggaaag
    12541 atgcctgaag cagtagaaga ggaatctcat gcactatcct atgatgaagt aaagtcaaaa
    12601 atgaatgacg aaa
//
LOCUS       DAVLHM010000052        12441 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLHM010000052 DAVLHM010000000
VERSION     DAVLHM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12441
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.052"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..459
                     /locus_tag="VXE45_001805"
     CDS             <1..459
                     /locus_tag="VXE45_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0789801.1"
                     /translation="RYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLK
                     HHYQIYQLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHY
                     SNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(589..1404)
                     /locus_tag="VXE45_001806"
     CDS             complement(589..1404)
                     /locus_tag="VXE45_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0789802.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(1401..2306)
                     /locus_tag="VXE45_001807"
     CDS             complement(1401..2306)
                     /locus_tag="VXE45_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0789803.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            2696..4015
                     /locus_tag="VXE45_001808"
     CDS             2696..4015
                     /locus_tag="VXE45_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV0789804.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIIDENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPLGG
                     DNWLTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQFDINNLIWRLYI
                     HSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLENYDIERAKKQYI
                     QELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTIISNNCVGGLIYK
                     QLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWTHEVYPLGHLGD
                     IDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNKMDNLPYSNKLI
                     LVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL"
     gene            4117..6246
                     /locus_tag="VXE45_001809"
     CDS             4117..6246
                     /locus_tag="VXE45_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0789805.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            6233..6682
                     /locus_tag="VXE45_001810"
     CDS             6233..6682
                     /locus_tag="VXE45_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0789806.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            6740..7012
                     /locus_tag="VXE45_001811"
     CDS             6740..7012
                     /locus_tag="VXE45_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0789807.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(7366..7557)
                     /locus_tag="VXE45_001812"
     CDS             complement(7366..7557)
                     /locus_tag="VXE45_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789808.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7985..8743
                     /locus_tag="VXE45_001813"
     CDS             7985..8743
                     /locus_tag="VXE45_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789809.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8745..10733
                     /locus_tag="VXE45_001814"
     CDS             8745..10733
                     /locus_tag="VXE45_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789810.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10775..11419)
                     /locus_tag="VXE45_001815"
     CDS             complement(10775..11419)
                     /locus_tag="VXE45_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0789811.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(11445..12440)
                     /locus_tag="VXE45_001816"
     CDS             complement(11445..12440)
                     /locus_tag="VXE45_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0789812.1"
                     /translation="MQNHYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKSAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
BASE COUNT         3832 a         2303 c         2512 g         3794 t
ORIGIN      
        1 cgttactgga aactcatcca acaggatagt cgtaaattga gcgataaacg tttttatcgc
       61 cctacttttc gcatgcactt aacaaataaa gaaattcttg acaagatttt aagctattca
      121 gaagacttga aacaccacta tcagatctat caactcttac tttttcactt tcagaataag
      181 gaaccggaga aatttttcgg actcattgag gacaatctta agcaggttca tcctcttttt
      241 cagactgtct ttaaaacctt tctaaaggac aaagagaaaa tcgtcaacgc ccttcaacta
      301 cactattcta acgccaaatt ggaagcgacc aataatctca tcaaacttat caagcgcaat
      361 gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga tttttatcgc cctgaatatc
      421 aaaaaagaaa gaacgaaatt tgtcctttct cgagcttagc tttttttcaa cccactacag
      481 ttgacaaaga gccaatctac aagtcactaa ttttcatata acaaaaaaac gaacaggctc
      541 tttttctgtt attcagaaga gaacttgttc gtttttatct tgattttctt aaaaagctct
      601 atatacatag ggattttctg gtttatcgac tttggtaaag ctgtcgattt ccaaggttgg
      661 aaggttttgt ttgagttctt tatggtagtg attgaccagt tttcctttgg ctgtaatcca
      721 ggtgttgttt tcatactgcc gggtattgcc cttggtcagc aatccataga caccagaatc
      781 tgcgatacag tggataatgc cgaatcggaa cagaaattga ctattggcat gactggggtc
      841 gttatagaca aagcctgtaa actggattgt cttgccctca aattcatctg gatagtcgta
      901 gatagcctcc atgacttcca tatagttttc attagtgatc tgaatactat cttgggataa
      961 gtatttatcc gccgccgttc gcatttcctt ttcataggct gattttgaaa aataagaact
     1021 agtatctggt ttcaaatatt ggcttgtcgt cccttcactt gtctgaatag ctagatccgt
     1081 tccttccgat agggggaaat gataaccttt agcagaaacg gtctgagaat ccaagctaac
     1141 agttgggaaa gttaagccga tgacaagtgg aatagccaga agagaaatac tcgtcatctt
     1201 ggccaatcgg ctgttcagat gactgtgggt tttgacttgc ttcatccaga tatacaattg
     1261 aacaattgcc aagataaagg aaagcaccat ggagatatag gccagatagg aatagtgcat
     1321 gttgatgtac tggtttagtt tgcccgacag atggaggtaa atagtcagtt caaaatagcc
     1381 agctaaaact aaaaatcgaa tcataggatg actccaatca agagagaata ggctaaaacg
     1441 accagagtca caatcgtaat gaagtgacta ataaatcgtg ctttcaagta atttttcatc
     1501 atgagaatat ttttgatatc cagcattggg ccaatgacga gaaaggccag aactggtgcc
     1561 aaaccgaaac tcgagagtag agaagcacct ataaaggcat ccgcctcact acagagcgaa
     1621 agaagaaagg ctaaaagcat caagagcagg atagcaaaaa gaggagtcgc actgatagag
     1681 gtcagaatcc gagtcggaac gtagacctgt attatagaag caaagaggca gccaaatacc
     1741 aaataacgcc ccgtatcaaa aaattcatca atggcctgca caaagacttg aaaaactttt
     1801 tttgcagaac tcaagtaaga aaaatcatgc tcatgacaag ccagacgatt ttctttctga
     1861 atcggttctt gccagaaaaa tcctagaaaa attcctagta ttacagccac aagaatggaa
     1921 cccagagctc gtaatagggc gacatggaag gagttgccaa aggcagaata ggtcgcaaaa
     1981 agaacaatgg gattgataac aggtgctgtc acaagaaaag gaacggccgt gtaacttgga
     2041 accttttttt ccagaaaacg attgatgatg gggacgattc cacattcaca agaagggaaa
     2101 agtataccga caaaggtccc aaaaaagatt ctcccccaac gatttcgagg gagaaaatga
     2161 taaaccttgt caggtgtgat ataaacttca atcagccctg agacaatgct tcctatcaga
     2221 acgaagggaa gggcttcaat gataatggag agaaaaatgg ctccagtttg aagtacacta
     2281 gatgggagtt gttgaaaagc agtcatctag tttttctttt ctgctttgac ttttttctct
     2341 ttgtcatcag ggaaagtaac ttgtttcaaa tcagggagtt tagcaaactc ttcaaacatc
     2401 ttgtccaagt cgtctcgttt tgtaaatttg acagccatag gtgtacctcg attctaaatt
     2461 ctacctctat tatactatta ttttgcggaa aagggaaaag ttaaaatttc aaattgagta
     2521 gctaagagat aatatagctt gatattacct gatatatatc ataattgtgc tataattaaa
     2581 taaaaagaaa atcattatca gaaaattatg ggaggtagtc aaactgactt actcaattag
     2641 tgttgttttg ttacatcaag gagataaaaa tagtttatta gagtctttgt caatagtgga
     2701 gagacaaaca ttaaaagata tagaagttat tattgtaaat caatctacag aggagatagc
     2761 ttccattagc caacagatga atctatcatt taatattaag attatagatg agaattcttt
     2821 tgctgagttg tctgatatga ttacaggaga ttatattacg tttctatctt caaatgattc
     2881 attatttgat tggacatttg aaaagatgta tcatgcgata aaattatccg attctgatgt
     2941 tgttcttggt cattttgctg atttggttga tggagtattt tacttttatc ctttgggggg
     3001 ggataattgg ttgacagaaa atttaacgaa tgttcaagtt ttacaaaaga tggatgatac
     3061 agatcatcga attagaaaac aatatcgctc attatttgga aaattattca atagtaagct
     3121 tttacgaaaa ataaatcaat ttgatataaa caaccttatt tggagacttt atattcactc
     3181 taaaactgca acctatatta atttcccgac atatatctat aaacctgtta tagatgctaa
     3241 acctctaaaa gactcctaca aaatcatatt agaaaattat gaaaatagaa tcaaagattg
     3301 cgccgtctta gaaaactatg atatagaaag agcgaaaaaa caatatattc aagaattggc
     3361 aaattttagt gcttggttaa aaaatgacgg tgaatattta gattctgata ttgtttatca
     3421 taagttaata gctgcagaga aaggaatttt cccttttctt gagcttgata gattagattt
     3481 tacgattata agtaataatt gtgttggagg attaatttat aaacagcttg gttttcaata
     3541 tagaacacct tttgttggtt tatttattct tcctgatgat tattataaac ttacaaagca
     3601 ttttcgttat tatatggaac aagaacttgt tttcgaagag gaacttattt caccgagctg
     3661 gactcatgaa gtttatcctt tggggcactt aggagatata gatattcatt ttctacatta
     3721 ttctagtatt gaagaagcac gaactaagtg ggaaaaaaga aaaaaacgca taaattggaa
     3781 taatctttat tttaaatttg ataataaaga ttcagctagt gaagaaattt taaataagat
     3841 ggataatctt ccttattcta ataaattaat tttagtcaat cgtccatata aaaatttgaa
     3901 aagtcaatgt gttattccag gtcaggaaca tcttccagaa ctggctatta tgtctgatcc
     3961 attaaatact tttgatatca tggcttggtt aaaaaaaggt ggcaatgctc tttaagtgca
     4021 agttattgcg ctgtagcata taaatctatt tcctacatat tttttaaatg ttctacgagt
     4081 taatttgaaa cgtttagctt gtggtataat agatttatgg ataaaaaata tgaaaaaatc
     4141 tctcaggatt tgggagtgac gttaaagcaa attgataccg ttctaagttt gacagctgaa
     4201 ggggcgacta ttccctttat cgcgcgttat cgcaaggaca tgactggtag tctggatgag
     4261 gtggcgatta aggctattat tgatttggat aaaagtctga caaatctcaa tgaccgtaag
     4321 gaagctgtct tagctaagat tcaagaacaa ggtaagttga ccaaggaatt ggaagaagct
     4381 atcttagttg ccgaaaaatt agcagacgtt gaagaactct atcttcctta taaggaaaag
     4441 cgtcgtacca aggcaaccat tgcccgtgaa gctggactct ttcctcttgc tcgtttgatt
     4501 ttgcagaata tagttgactt agagaaagaa gctgaaaagt tcgtctgtga aggatttgcg
     4561 actggcaagg aagccttgac cggtgcagtt gatattttgg tcgaagcctt atcggaagat
     4621 gtgaccttgc gttctatgac ttatcaggaa gtgctgagac actctaaact cacttctcaa
     4681 gccaaggatg aaagtcttga tgaaaagcag gtttttcaga tttattatga tttttcagag
     4741 acagttggaa ctatgcaagg ctatcgtacc ttggctctca atcgtgggga gaaacttggt
     4801 gtcttgaaga tcggttttga acatgcgacg gaccgtattc ttgccttctt tgctactcgt
     4861 ttcaaggtga aaaatgctta tattgatgaa gttgttcagc aatccgttaa gaaaaaggtc
     4921 ttgcctgcta ttgagcgtcg tattcggaca gaattaactg agaaagctga agagggagct
     4981 atccaacttt tttctgacaa tctgcgcaat ctcctcttgg ttgctccact gaaagggcgc
     5041 gtggttcttg ggtttgaccc agcctttcgt acaggtgcca agctagctgt cgtggatgca
     5101 acaggaaaaa tgctgacaac tcaggttatt tatcctgtta aaccagcatc agctcgtcaa
     5161 atcgaagaag ccaagaaaga tttagcagat ttaattggtc aatacggtgt agagattatt
     5221 gccattggaa atggaacggc cagtcgtgaa agtgaagctt ttgtagcgga agttctgaaa
     5281 gatttccctg aagtcagcta tgttatcgtt aatgaaagtg gtgcttctgt ctattctgcc
     5341 agcgaacttg ctcgtcagga gtttccagac ttgaccgttg aaaaacgctc tgccatttct
     5401 atcgcccgtc gtttgcaaga tcctcttgcg gaattggtca aaatcgatcc taagtcaatt
     5461 ggtgtcggtc aataccaaca cgatgtcagt cagaagaaac tatctgagag tctggacttt
     5521 gttgtcgata cagtggttaa ccaagttggt gtcaatgtca atacagctag cccagctctt
     5581 ctttcacacg tagctggact caataaaacc atttctgaaa atatcgtcaa ataccgtgag
     5641 gaagagggaa aaatcacttc acgctcccaa atcaagaaag ttcctcgttt gggggccaag
     5701 gcttttgaac aggctgctgg tttcctccgt atccctgaaa gtagcaatat ccttgataat
     5761 acaggagttc acccagaaaa ttacgctgcc gttaaggaac tcttcaaatg cttggacatt
     5821 aaggatctga atgaagaggc ccaaagtaaa ctcaagtcgc tttcagtcaa ggaaatggcg
     5881 caagagttag accttggtcc agaaactctt aaagatatca ttgcagatct tctcaaacca
     5941 ggtcgagatt tccgtgattc ctttgatgct ccagttctcc gtcaagatgt cctagatatc
     6001 aaggacttag tggttggaca aaagctagaa ggagtggtgc gtaatgttgt tgatttcggt
     6061 gcttttgttg atatcggaat tcatgaggac ggtctcatcc atatttccca tatgagtcgc
     6121 aagtttatca aacaccctag tcaagtggtg gcagttggag atttggtgag cgtttgggtt
     6181 aagaaaattg atactgaacg tgaaaaagtt aatctgtctc tcctagctcc aaatgaaact
     6241 gactgattac gtcaagcagg tttcactaga agacttcggc agacctttta tccatcatgt
     6301 ccagtggaat aggcgtctac gttcgacagg tgggcgattt ttccccaaag atgggcattt
     6361 ggattttaat cccaaggttt atcaggaact ggggttggac gtttttagga aaattgtccg
     6421 acatgaactc tgtcattatc acctctattt tcaagggaaa ggctatcaac acaaggatcg
     6481 ggattttaag gaactgttga aagcagtgga tggattacgg tttgtaccat ccttgcccaa
     6541 tagtaactcc aagccaatca agctctatcg ttgccaatcc tgccagcaaa cttatcagcg
     6601 taagcgtagg attgataccc aacgctatcg ctgtggactt tgtcgaggaa agttgctatt
     6661 agtaaatcag cctgaggact gatgaaagcc gagcctatcc gtgatatact agtctaacct
     6721 agcagaaaga ggaaatatca tgaacagtaa gttttataaa atgagacgaa atcgcatgat
     6781 ttcaggagtt ttagcaggtc tgtcagacaa gtggaacttt gatgttaccc ttgtacgttt
     6841 tctgtttgcc atttttacag tcgcaaactt tggacttggg gtgattatct atatcatcct
     6901 agcttctatc atgccaacca aggaagaaat cgaagcagaa atgtacggaa caggcccacg
     6961 taaacgcaaa gaagctcaag ccattgacga taatgaaggc tggttttggt gaggttttac
     7021 aaaagatttg gaatacgcaa aaagctttaa atcaatagtc taaactgctt gatttaaagc
     7081 ttttttactt ttatactcaa taaaaatcaa agtgcaaact aggaagccag ccgcaggctg
     7141 taatttagtc ggcaatgtga agttgatata gtttgcactt tgatttttga atagtattaa
     7201 taatatttcg ccagcttcat ccacaaacta tagtggattg gaactagaat aggacaccta
     7261 tacttctaaa aaattgttag aaatcgattt gactgtcctg atcgatttgt cctgttctta
     7321 tttcatttta ctataaaagc agtaatttaa acgcagtttt ttaatctatt tttgctgttg
     7381 agacaataca tttttggaaa aatggtggat gctgataaca actgataacc agcaaataac
     7441 ataagcagtg ccggtaaatt ctgtaccgat aaagtgtgtg tgttcaacta agagctgacc
     7501 gatgaatgga gagagcagat agagaagtcc gatgagtata tgttctttgt gtttcattaa
     7561 agcgcacctt ctttccttat aggttgaacg acttgcaagt gttaaattga atggtatgtt
     7621 atctaggtaa ccttactaaa atgttagttc ccgcttcctc cttttcaaag taagcctttt
     7681 cacacttata ttttacaact ttaaaaatag gaaatcaaat cattttctaa gtaattttgc
     7741 ttatatttca cccaatctta caaaaatgta agattaaagt ctcttttgta aggttaggtt
     7801 atggcaagcg gtcttttttt gatgtaaact agactcataa agaacaaagg agtaacatca
     7861 tgaaacaaat cttacataag aaaactagaa aaccaagtca caaagaaatt gagcgcgttc
     7921 agctgggatg cactatgatg caagctacat ttcatttgat gggatattaa gaaaggagat
     7981 tctcatgaca cttttagatg taaaacacgt tcaaaaaatt tataaaacac gttttcaggg
     8041 caaccaagta gaagccctca aggatattca ctttaccgtc gaaaagggtg actacgttgc
     8101 catcatgggt gagtctggtt ctggtaaatc aactcttctc aatattctag ctatgctgga
     8161 taaaccaagt cgtggtcagg tttacttgaa tggaactgac accgcaacca ttaaaaattc
     8221 acaggcctct agcttccgtc gtgaaaagtt gggctttgtc ttccaagact ttaacttgct
     8281 agatactcta tctgtaaagg acaatatctt gcttccgctt gtcttgtcaa gaagacctat
     8341 tacagagatg atgaagaaat tggtggtgac agctgagaat ctgggaataa accaattaca
     8401 agagaagtac ccttacgaga tttctggtgg tcagaaacag cgtgtagcag tagcccgcgc
     8461 catcatcaca gaacctgaaa ttctccttgc ggacgaaccg acaggagctc ttgactccaa
     8521 gtcatctgca gccttacttg atgtctttga tgaaatcaat gagcgcggcc aaaccattct
     8581 catggtaacc cactcaacag cagcagctag cagagctaaa cgtgtactct ttatcaaaga
     8641 cggcattctt tacaatcaaa tctaccgtgg agagaagaca gaacgtcaga tgttccaaga
     8701 aatctctgat accttgactg tcatggcaag cgaggtgaat tagtatgttt cgattaacca
     8761 ataagttagc ggtatcgaac ttgattaaaa accgcaaact ctactatcct tttgcgctgg
     8821 ctgttctctt ggcagtcact gtcacctatc tcttttactc tctaaccttc aatcctaaga
     8881 ttgcggaaat ccgtggagga acaaccattc aggctacact tggatttggt atgtttgtcg
     8941 tcacccttgc gtcagccatt atcgttctct atgccaatag ttttgtcatg aagaaccgtt
     9001 ccaaggaact aggaatttat ggcatgttgg gcttggagaa gcgtcatctt atcagtatga
     9061 cctttaagga gttagtggta tttgggattc taactgttgg agcgggtatc ggtattggag
     9121 ccttgtttga caagttgatt ttcgctttcc tactcaaact gatgaaattg aaggtggaac
     9181 tggtcgctac cttccagatg aaagttgtca ttacagtact tcttgtcttc ggtttgattt
     9241 tcctaggcct catgttcctg aatgcccttc gaatcgcccg tatgaatgcc ctccagctct
     9301 cacgtgagaa agctagcgga gagaaaaaag gtcgcttcct tcctctccaa actattcttg
     9361 gttccataag tttagggatt ggatattatc ttgcccttac ggtaaaagat cctcttacag
     9421 ccttaacaac cttcttcata gctgttttac tggttatctt tggtacttat cttttgttca
     9481 atgcagggat taccgttttc cttcaaatct taaagaaaaa taagaaatac tattaccaac
     9541 ctaataatct catatctgtt tctaacttga ttttccgtat gaagaaaaat gcagttggac
     9601 tagcaactat cgctattttg tcaacaatgg ttttggtaac catgtcagca gcgacaagca
     9661 ttttcaattc cgcagaatcc tttaaaaaag ttctaaatcc tcatgatttt ggggtttcag
     9721 ggcaaaatgt tgaaaaagaa gatttggaca aactcttgag ccagtttgca agtgacaaag
     9781 gttataagat taaagagaaa gaagtgcttc gttacagtaa ctttggtatt gcaaatcaag
     9841 aaggaaccaa gttaactatt tttgaaaaag gacaaaaccg tgtccaacca aaaacagttt
     9901 tcatggtatt tgaccaaaaa gattatgaaa atatgactgg tcaaaaactg tctctatcag
     9961 gaaatgaggt cggtctcttt gccaaaaatg acggactgaa aggacagaaa gctctaactc
    10021 taaatgatca tcaattttct gtcaaagaag aatttaataa agatttcatt gtcaaccatg
    10081 ttccaaataa gtttaatatc ttgactactg attacaatta ccttgttgtt cctgatttac
    10141 aagccttttt ggatcaattc ccagattcgg ctatctataa tcagttttac ggtggtatga
    10201 atgtagatgc cagcgaagaa gaacaactca aggtcgctga ggagtatgaa aactacctca
    10261 atcaatttaa tgctcaatta gacacagaag gtagctatgt ttatggtagc actctagcag
    10321 atgctagtgc tcagatgagt gccctctttg gtggtgtctt ctttatcggt attttcctat
    10381 ccattatctt tatggtcgga actgttctgg tcatctacta caaacaaatt tctgaaggct
    10441 acgaagaccg tgaacgcttt attatcttgc agaaagtcgg tttggaccaa aagcaaatca
    10501 agcaaaccat caacaaacag gttttaactg ttttcttcct tcctttgctc tttgccttcc
    10561 tacatctagc ctttgcctac catatgctta gcctgatttt aaaagtgatt ggtgtactgg
    10621 atacgactat gatgttgatt gtgaccttgt ctatctgcgc tatcttcctc atcgcctatg
    10681 tgctgatttt tatgattact tcaagaagtt atcgcaagat tgtgcaaatg taaaaaagat
    10741 acctcgactt caaaatcgag gtatttcttg tattctaaat gctgaaaagt tgttcgagca
    10801 ggaaggtaac tcccatggtc aagagaccaa tagcaaggtt ccgaatcata gctgttttgg
    10861 ttggggcttt tccaagtcta gcacttgtgt aaccagtgag aagaagggcc acaccgacaa
    10921 taaggacggt agcagggatg cggtaatcac ttggaaaaat ggtcactgac agcattggag
    10981 gcaaacttct aaggaaaaag gcaacgaagc tagaaatggc agcgtgccaa ggattggtaa
    11041 attcttcata ctcaatccca tatttttcct ctaccagagc cttgagtgga tttttaagaa
    11101 agatcttatt agtcaagagt tgggcagaag ttttgaattc tccattttgg atataagaag
    11161 catagaggga ttttttggct agttccctat cttggtctag caagagtttt tctcgcgaaa
    11221 cggcagcttc ctcggtatct tttggagttg aaacggatac atattctcca ccagccattg
    11281 aaaaggcacc agctaagata gccgcaaaac ctgataaaaa gataatccag atattgctcg
    11341 tggcactggc aactccgata accacaccag caatggaaat aattccatcg ttagcatcaa
    11401 gaacacccgc acgcaggata tttaaacgac ctgcaaaatt tgaatcaatt tcgtgatttg
    11461 tttctgacgc taaatttcaa gttcaagtta gccatccaga agtcttctct gggtgacttg
    11521 tagtccaagc attttttagg atagttgtta atccactttt cgatgaatgc gacttctttg
    11581 ggagtcattt tcttgattcc cttaggtaac catctacgaa tgagcctgtt gtgattctca
    11641 ttagttcccc tttcccaaga ggcatagggg tgcgcataat agatgtgctc ctcagaaaat
    11701 acatcaaaca agcgattgaa ttccgttcca ttatctgccg tgatggaaag aatcttgtgt
    11761 tgttttaaga tgagttttag agcctgattg accacatcag cacttttatt tggaatcaat
    11821 cggatgatct gatgtctact ctttcgatcc gtcaagacaa gcaaacagta gtttttcgct
    11881 ctcgtaagta gaaccgtatc aatctcataa tgcccattct ccaagcgaag attgatagct
    11941 tcagaccgct gttcgatgga ttgaccagca gatttaaagt tggtgctagc ctgtttctta
    12001 agcgcttttc cttttctagg gtaaagcaga tcctgtttgc ttaaccccaa ttttccatga
    12061 tgaatccaat agtaaatggt tgaaattccc acgttaaccc ctttaaccat caccatcatt
    12121 tcaggcgaaa atttttggtt atgatagtgg agaatctttt cctttagttc cttggtcacg
    12181 cttgatttcc tgaccgagcg cttgcgattg ttttcataag actgttgagc atagtcggca
    12241 gaataaacct ctttgaagcg cccttttcca agacattgtc ggactgtccc acgcttgatt
    12301 tcagtgtgga tagtttgagg aacttttcca agcagagagg caatttctct atttgatttt
    12361 ccttcttttt tccatcgttc gattaagcga cggctatcga ttgtcaaatg tttacctttt
    12421 gtagtataat ggttttgcat c
//
LOCUS       DAVLHM010000053        12091 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLHM010000053 DAVLHM010000000
VERSION     DAVLHM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.053"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            143..298
                     /locus_tag="VXE45_001817"
                     /pseudo
     CDS             143..298
                     /locus_tag="VXE45_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            498..3773
                     /gene="rexB"
                     /locus_tag="VXE45_001818"
     CDS             498..3773
                     /gene="rexB"
                     /locus_tag="VXE45_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0789813.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3770..7420
                     /gene="addA"
                     /locus_tag="VXE45_001819"
     CDS             3770..7420
                     /gene="addA"
                     /locus_tag="VXE45_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0789814.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFCFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     HVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7635..8813
                     /locus_tag="VXE45_001820"
     CDS             7635..8813
                     /locus_tag="VXE45_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789815.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSIC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDYRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9022..12027
                     /locus_tag="VXE45_001821"
                     /pseudo
     CDS             9022..12027
                     /locus_tag="VXE45_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
BASE COUNT         3969 a         2328 c         2529 g         3265 t
ORIGIN      
        1 ttttggttca ttttactata gtagattgaa ataagatacg aacagcttga ttagggaaat
       61 caaattaatt tctagaaata ttttagcatc cacggtgtac tattatagtt tcaatttact
      121 atagttcaat cattctatca agaatattga atatataaag gcacgtaata ttaaaacttc
      181 ttctgatatc gaattagagt ccgatgttga tggcgataaa tcagacaatc tacccgtcga
      241 cattaagata ctgggacaac acattgaagt gtattccgta cctaagaaac aatcataaaa
      301 ctcaaagcct tgttaccgag gcttttttat tatgtgattt tcagtagcca gacttattct
      361 atctaataca agtaaagcta agtatttaag atttagcaga tgatgaagaa aagaaaggat
      421 ggcctaaata ttttaacaga tttacgaggc taatcatggt ataatatagg gtgatgaaaa
      481 attccaacga ggctgagatg aaattacttt atactgatat tcgaacttct ttgacagaaa
      541 ttctaacaag agaggcagaa gagctagttg cagctggcaa gcgggtcttc tacattgccc
      601 ccaactctct ttcttttgaa aaggaacgcg ccgtgctgga atgcttgtcc cagcaggctt
      661 ctttttcgat taccgtcacg cgctttgctc aaatggctcg ttatctggtc ttgaatgatt
      721 taccagctaa aactactctt gatgatatcg gtcttgggtt ggccttttac aaatgccttg
      781 ccgaactcga tcccaaggac ttgcgtgttt atggcgctat taagcaggat cctcaattga
      841 tccagcagtt aattgagctt taccatgaga tgaccaaatc tcagatgaat tttttggact
      901 tggagaattt aacagatgag gataagaggg cggatttact cttgattttt gagaaagtaa
      961 cagcctatct taatcaaggg cagttagccc agggaagtca gttgtcccat ttgattgagg
     1021 ctattgagaa tgacaaggta agtagtgatt ttaatcaaat cgccttggtc attgacggct
     1081 ttactcgttt ttctgctgag gaagagcggg ttgtggactt acttcacggc aaaggtgctg
     1141 agattgttat cggggcttat gctagtaaga aagcctatac cagtcctttt agcgagggca
     1201 atctctacca agccagcgta aaatttctcc atcatctggc ttctaaatac caaacgcccg
     1261 ctcaggactg ttctcaaact catgagaaga tggatagttt tgacaaggcc tctcgtttgt
     1321 tggagtcttc ttatgacttt tcagaactcg ctttggatgt cgatgagaaa gaccgtgaaa
     1381 atttacaaat ctggtcttgt ttgacgcaaa aggaggagtt ggagctagta gcccgtagca
     1441 ttcgtcagaa attacatgag aactcagacc tgagctacaa gcattttcgt attctcttgg
     1501 gggatgtagc ttcttaccag ttatctctca aaaccatttt tgaccagtat cagattcctt
     1561 tttatcttgg tagaagcgaa gccatggctc atcatccctt gactcagttt gtcgagtcta
     1621 ttttagcttt aaaacgttac cgttttcgtc aggaggattt gattaatctt cttagaactg
     1681 acttgtatat tgacctcagt cagtctgata ttgatgcttt tgaacaatat atccgctatc
     1741 ttggtattaa tggcttgcca gcctttcagc aaaccttcac caaatcccac catggaaaat
     1801 ttaatcttga gcgtttgaat gtcctccgcc tgagaatttt agcacctctt gaaaccctct
     1861 ttgccagccg aaaacaaaag gctgaaaacc tcctacaaaa atggagtgtc tttctaaaag
     1921 aaggagctgt gaccaagcag ttacaagatt tgacaaccac tttggaagct gtagaacagg
     1981 aaagacaagc cgaagtttgg aaggcttttt gccatgtttt agaacaattt gcgactgttt
     2041 ttgctggttc acaggttagt ctggaagact tcctagcctt gctccattct ggaatgagtt
     2101 tgtcccaata ccgtaccatt ccagcaacag tggacactgt tctggtgcag agttacgatt
     2161 tgattgcacc attgactgct gactttgtct atgctattgg actaactcag gacaatttac
     2221 caaaaatttc tcaaaacacc agtcttctga cagatgaaga aaggaaaaac ctaaaccaaa
     2281 cgaccgaaga aggcgttcaa ttactgattg ccagcagtga aaatctcaag aaaaatcgct
     2341 acactatgct ttccttggtc aattctgctc gtaagcagtt gttcttgtcg gctccaagcc
     2401 tttttaacga aagtgaaagt aaggaatctg cctatcttca agagttgatc cattttggat
     2461 ttaggcggag agagaagagg atgaatcaca aaggactgtc taaggaggat atggggtcct
     2521 atcacagtct tttgtctagt ctggttgcct atcaccagca gggtgagatg agcgatactg
     2581 agcaagattt gacttttgtc aaggttctgt cgcgtgtcat aggtaaaaaa ctagatcagc
     2641 aaggtctgga aaatccagct atcccaacca gtccaagcag caagacctta gccaaggaca
     2701 ccttgcaagc tctctatcct gccaaacagg agttttacct gtctacgtcg ggtttgacag
     2761 agttttatcg caatgaatac agttatttcc tacgctacgt tttaggcttg caggaggaat
     2821 tacgtttgca tcctgatgcc cgtagtcacg ggaatttctt gcatcgtatc tttgaacgcg
     2881 ccttacagtt gcctaatgaa gattcctttg accaacgtct agaacaagct attcaagaaa
     2941 ccagtcaaga acgcgaattt gaagctattt atcaagaaag tttggaagcc cagtttacca
     3001 aggaagtttt gcttgatgtt gcacggacga ctggacatat tctccgacac aatccagcca
     3061 tcgaaaccat caaagaagaa gcaaattttg gtggaaaaga ccaagccttt attcaattag
     3121 acaatggacg cagtgtcttt gtacgaggca aggtggaccg gattgaccgt ttgaaagcta
     3181 atggagcgat aggagtagta gactacaaat ccagtctgac tcagttccag tttcctcatt
     3241 tctttaatgg gctcaattct cagttaccaa cctatcttgc tgccctaaaa agagaagggg
     3301 agcagaactt tttcggcgcc atgtacttgg aaatggctga acctgtccaa tctctgatgg
     3361 cggtaaaaag tctggcagga gcagtggtag aagccagcaa atctatgaaa taccaagggc
     3421 tcttcttgga aaaagaaagc agttatttag gcgaatttta taacaaaaac aaggctaatc
     3481 aactgacaga tgaggaattt cagctcctac tggactacaa tgcctatctt tacaagaaag
     3541 ctgctgagaa gattttagca ggccggttcg ccatcaatcc ttatactgaa aatggcagaa
     3601 gcattgcccc atacgtccag caacatcagg ctattacagg ctttgaagcc aattaccatc
     3661 tgggccaagc ccgtttccta gaaaagttgg acctagctga tggcaagcgt ctggtcggag
     3721 aaaaactcaa gcaagcttgg tttgaaaaaa taagagagga gttaaatcga tgaagcttat
     3781 tcccttttta agtgaggagg agattcaaaa actgcaagaa gcagaagcaa attcgagcaa
     3841 ggaacagaag aaaactgccg aacaaatcga agctatctac acttctggtc agaatatcct
     3901 ggtctcagca tcggctggtt ctggaaagac ctttgtcatg gtagagcgca ttctggacca
     3961 attggcgcgt ggtgtcgaaa tttctcaact ctttatctca acctttaccg tcaaggctgc
     4021 aactgaactt aaagaacgtt tagagaaaaa aatcagcaag aaaatccaag aaacagatga
     4081 tgtcgatctc aaacaacact tgggttgcca gttggcagac ctacccaacg ctgccatcgg
     4141 aaccatggac tctttcacac aaaaattcct tggcaaacat ggttatctgc ttgatattgc
     4201 acctaatttc cgtattttac aaaaccaaag cgagcaactt cttctcgaaa acgaagtctt
     4261 tcatgaggtc tttgaagcgc attaccaagg taaacagaaa gagagcttta gtcatttgct
     4321 gaaaaacttt gctgggcgtg gcaaggacga acggggtctg cgccagcaag tctataaaat
     4381 ctatgacttc ctccaatcca ccagtaatcc tcaaaagtgg ctgagtgaat ctttcctcaa
     4441 aggctttgag aaagctgatt ttaccagtga aaaagaaaaa ctgactgagc aaatcaaaca
     4501 agccctctgg gatttggaaa gctttttccg ttaccatctg gataacgatg ccaaggagtt
     4561 tgcaaaggct gcctatttag aaaatgttca gttaattctg gatgaaattg gctccctaaa
     4621 tcaggagttc gatagtcagg cttatcaggc agtacttgcg cgtgttgtcg ccatctctaa
     4681 ggagaaaaac ggtcgtgctc tgactaatgc cagccgtaag gctgatttga agcccctggc
     4741 tgatgcctac aacgaagaga gaaagaccca gtttactaaa ctaggacaat tatcagacca
     4801 gatagcgatt ctcgactatc aagaacgtta tcatggagac acttggaaac tagctaaaac
     4861 cttccaatct ttcatgagcg attttgtaga ggcttatcgt cagagaaaac gacaggaaaa
     4921 tgcctttgaa ttcgctgata tcagccatta caccattgag attttagaaa atttcccaca
     4981 agttcgtgag tcttatcagg agcgcttcca tgaagtcatg gtcgatgagt atcaggatac
     5041 caaccatatt caagaacgga tgctggaatt gttgtctaat ggccacaatc gctttatggt
     5101 gggagatatc aagcaatcca tctatcgttt ccgtcaggca gacccgcaga ttttcaatga
     5161 gaaattccaa cgctatgcgc aaaatcctca agaaggcaag ctcattctcc tcaaggaaaa
     5221 tttccgtagt agttcagaag tgctgtcagc aaccaatgat gtctttgaac gtctcatgga
     5281 ccaagaggtc ggcgaaatca actatgataa catgcaccag cttgtttttg ccaataccaa
     5341 actgactccc aatccagaca acaaggctga atttctcctc tacgacaagg acgatacagg
     5401 tgaggaagaa gagagtcaaa cagaaacgaa actaacaggc gaaatgcgct tagttatcaa
     5461 ggagattctg aaacttcatc aagaaaaagg tgttgccttt aaggaaattg cccttctgac
     5521 ctccagccgc agtcgtaatg accagattct cctcgccctg tctgagtacg ggattcctgt
     5581 caaaactgac ggagagcaaa acaattatct ccaatcccta gaagtgcaag tcatgctaga
     5641 cactcttcgt gtcattcaca atcccctgca agactacgcc ttggttgccc ttatgaagtc
     5701 tccaatgttt tgttttgatg aggatgagct agcacgtttg tcccttcaga aagcagagga
     5761 taaagtccac gaaaatctct atgagaaact ggtcaatgca caaaaaatgg caagtagtca
     5821 aaaaggcttg attcacacag ctctagctga aaaactaaag caattcatgg atatcctagc
     5881 ttcttggcgc ttgtatgcca aaccccactc tctctatgac ttgatttgga agatttacaa
     5941 cgaccgtttt tattatgact atgttggggc tttgccgaat ggtcctgcta ggcaggccaa
     6001 tctctatgcc ctagcactgc gtgctgatca atttgaaaag agcaatttca aaggtttgtc
     6061 gcgttttatt cgtatgattg accaagtctt agaagcccag cacgatttgg caagcgtggc
     6121 cgtcgcaccg ccaaaagatg cagtagagct catgaccatc cacaagagta aagggctgga
     6181 gtttccttac gtctttatcc tcaatatgga tcaagatttc aacaagcaag actctatgtc
     6241 agaagtcatt ctcagtcgtc agaatggtct tggtgtcaaa tatattgcca agatggagac
     6301 aggggcagta gaagaccact atcctaaaac catcaaactc tccattccta gtctgaccta
     6361 taggcagaac gaagaggaat tacagctagc aagctattct gagcagatgc gtttgctgta
     6421 tgttgctatg acgcgggctg agaaaaagct ctatcttgtc ggcaagggtt ctcgtgaaaa
     6481 gctggaatcc aaggaatacc cagcagccaa aaatgggaaa ctaaatagca atactagact
     6541 gcaagcacgg aatttccaag attggctttg ggctatcagt aaagtgttta ctaaggacaa
     6601 gctcaacttt agttatcgtt ttattggcga agatcagttg accagagaag ctatcggaga
     6661 gttggaaacc aagagtcctc tccaagatag ctcccaagca gacaatcgtc agtcagatac
     6721 catcaaagaa gctctggaaa tgctgaagga ggtggaagtt tataatactc ttcaccgcgc
     6781 agctattgaa cttcctagtg ttcaaacccc aagtcaaatc aagaaattct acgaaccagt
     6841 tatggatatg gaaggtgtcg agattgctgg tcaaggtcag tcagtaggca agaaaatcag
     6901 cttcgatttg ccagattttt caaccaaaga aaaggtaact ggagctgaga ttggtagtgc
     6961 tactcacgaa ctcatgcaga gaattgacct cagccagcaa ctaacccttg ctagcctaac
     7021 agaaacactc aaacacgttc aaactagcca agctgtcaga gacaagatca atcttgataa
     7081 aattcttgct ttctttgaca cagtactcgg tcaggaaatt cttgctaata ccgaccatct
     7141 ctatcgcgag caacctttct ccatgctcaa acgagaccaa aagagtcagg aagactttgt
     7201 tgtccgtggt atccttgatg gctatctgct ttacgaaaac aaaattgttc tgttcgacta
     7261 caagacagac cgctatgatg aaccaagtca actcgtagac cgctatcgtg gtcagttagc
     7321 tctatacgaa gaggctttat cacgagccta ttcgattgaa aatattgaaa aatacttgat
     7381 tttactcggt aaagacgagg ttcaagttgt aaaagtataa cttatactct ttgaaaatct
     7441 cttcaaacca cgtcagcttc gccttgctgt atatatggtt actgacttcg tcagttctat
     7501 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tctatctaca acctcaaaac
     7561 agtgttttga gctgactgcg gctagctttc tagtttgctc tttgattttt attgagtatt
     7621 agaaaggaga cctcatgaca cttccagtta gaaaatccct gcacgatgca gttttacagg
     7681 cttcgaaagc ggatacttgg gaacaagcta ccaaggaatg gaatgaagtt tccttgattt
     7741 ttaacggtat cggccgtagc atttgtgtct gtggaaatgt catcaaatac gcttatgaac
     7801 tctttaacgg tgtcacaggc caacgcctct ttccaattgg tagcgactgt gttcgtcatt
     7861 ttcatcgatt gtcccttgac cagcaattgg aagaggaaga aaaactgctc agaaaggttg
     7921 aaaatctaac cagaaaagct cagaaaaagg aaaaaatcaa ggtcaataaa agtgactttg
     7981 acgagcgact tctaaaatgg ctctgggaaa aaggtgtttt caaacccaat cgtggcaatc
     8041 aatttgcgcc tgagagagac taccagcttt tcctagaagt ctttcaggga ggaagttgga
     8101 ccaaggcgga accaaagaaa aaggctcgga tggaagaagt ccttgaaaag tgtatcaaac
     8161 cctttttact tgggaaatcg gatgaccaac tctaccttgt caagctaggc aaggagaaaa
     8221 ttgactacga acaagaactc cgtatccagg cagagaaaga acgcaagaag agggataaaa
     8281 tcgccaagca atatgcagac aatctggttc tagccatggg acccgcagag cgtgcttatc
     8341 aagattactt tggctttaca gagaccctga ctcaagaaga acgcaagtgg gaaaaaattc
     8401 tttttggtaa aaatagagca gaacgggcta ttaaggccaa acaataccaa aaagagctgg
     8461 aaaaagacca acgaattgcc agtcaggatc caattgaaag aaaacagaaa cagacttggc
     8521 tcctcaattc ctattttcgt gagcttcctg aagaaaaagc tcgattttct aggctcttat
     8581 tagaatatcg aaaaaatggt gaagtaccct tttcaactga atacctgtca gatcatctca
     8641 tcgacttttt ctataaaatg aaagcctttg aatttgaaat cgcaccagaa caagtccgag
     8701 attttctaaa aaaaagcctg caggaagact atcgctcatc agcacaagga agctggatag
     8761 aaggaattct cctcaactgc ctcaaaccat ttttagaacg attagtgata tgagtaacac
     8821 ctaccgtgta aatttcatgg taggtgttat tgtaccccca aataatataa aacaaagtat
     8881 gaaagcgcat ctcaatttta agactttttt gtaaattaag agtataatta aggtatactg
     8941 ccttttctat agataataga taatacacta atataataaa ggtctttgta acatatataa
     9001 attttatttc aaggaggaat aatggaaaag tattttggtg aaaaacaaga gcgtttttca
     9061 tttagaaaat tatcagtagg acttgtatct gcaacgattt caagtttatt ttttatgtct
     9121 gtattagcta gttcatctgt ggatgctcaa gaaactgcgg gagttcacta taaatatgtg
     9181 gcagattcag agctatcatc agaagaaaag aagcagcttg tctatgatat tccgacatac
     9241 gtggagaatg atgatgaaac ttattatctt gtttataagt taaattctca aaatcaactg
     9301 gcggaattac caaatactgg aagcaagaat gagaggcaag ccctagttgc tggtgctagc
     9361 ttagctgctc tgggaatttt aatttttgct gtttccaaga aaaaggttaa gaataaaacg
     9421 gtattacatt tagtattggt tgcgggaata ggaaatggtg tcttagtttc agtccatgct
     9481 ttagaaaatc atcttttgct aaattacaat acggactatg aattgacctc tggagaaaaa
     9541 ttacctcttc ctaaagagat ttcaggttac acttatattg gatatatcaa agagggaaaa
     9601 acgacttctg attttgaagt aagtaatcaa gaaaaatcag cagccactcc tacaaaacaa
     9661 caaaaggtgg attataatgt tacaccaaat tttgtagacc atccatcaac agtacaagct
     9721 attcaggaac aaacacctgt ttcttcaact aagccgacag aagttcaagt agttgaaaaa
     9781 cctttctcta ctgaattaat caatccaaga aaagaagaga aacaatcttc agattctcaa
     9841 gaacaattag ccgaacataa gaatctagaa acgaagaaag aggagaagat ttctccaaaa
     9901 gaaaagactg gggtaaatac attaaatcca caggatgaag ttttatcagg tcaattgaac
     9961 aaacctgaac tcttatatcg tgaggaaact atagagataa aaatagattt tcaagaagaa
    10021 attcaagaaa atcctgattt agttgaagga attgtaagag taaaacaaga aggtaaatta
    10081 ggtaagaaag ttgaaatcgt cagaatattc tctgtaaaca aggaagaagt ttcgcgagaa
    10141 attgtttcaa cttcaacgac tgcgcctatt ccaagaatag tcgaaaaagg tactaaaaaa
    10201 actcaagtta taaaggaaca acctgagact ggtgtagaac ataaggacgt acagtctgga
    10261 gctattgttg aacccgcaat tcagcctgag ttgcccgaag ctgtagtaag tgacaaaggc
    10321 gtaccagaag ttcaaccagc gttgtccaaa gcagttataa ccgacaaagg tgagactgag
    10381 gttcaaccag agtcgccaga tactgtggta agtgataaag gtgaaccagc agtccaacca
    10441 gagctaccgg aagcggttgt gactgacaaa ggtgagactg aggttcaacc agagtcgcca
    10501 gatactgtgg taagtgataa aggtgaacct aaacaggtag caccgcttcc agaatataca
    10561 ggaccacaag ccagcgctat tgttgaacca gagcaggtag caccactacc agaatacaca
    10621 ggggtacaag ccggatcgat agtcgagcca gagaaagtag aagcaccgaa agaatatact
    10681 ggtaaaatcg aacagcctag tgcagaagat actaaacctg aaaatggggc aagctctaca
    10741 aatggggaat cggaacgtcc taaagataaa attaaagaag aaaaacaagt cgacaagaaa
    10801 ctagaactta gaaatgtttc aaacgtggaa ttatatacgg tagaaaataa taaatatcga
    10861 catattacgg ctgtagatgg tgctttagat agttcattga agtatttcat gaaggtaaaa
    10921 tcagaaaatt ttaaagatat aatgttgcct gttactaaaa ttgaaagtac aacaaaaaac
    10981 aataaagaag tatacaaaat tgtggctcat gcagaaaatc taattcaaca cgaaaacaat
    11041 gttatttcga atgactatac atattattta ccaaaaactc agcaaagtga aactggcgtc
    11101 tatacatcat ttaaaaattt agttgatgca atgaatagtg accctaatgg aacattccat
    11161 ttaggtgcaa ctatggatgc tcgtgaagtt gaacttccgg atgatcaaga aagttatgta
    11221 aaaaatgaat tttacggaaa attaataggt aaaaataatg gtaagtatta tgctatttat
    11281 aacttgaaaa aacctttatt taaaactcta aacaccgcta ctattcagaa tctttcaata
    11341 aaagaagcga atgtttcttc taaagaagat gctgctacaa tatcgaaaga agcaaaatac
    11401 aatactctta tagataatgt tcattctgat ggtattatag ctggtgaacg tggaattggt
    11461 ggattggttt caaaagtaga taactcgaga atttctaata gtagttttac aggcagaata
    11521 actaacacat atgatacaac tgcagggtat gaaattggtg gtttagtagg taaactttct
    11581 ggttcgcttg cttctataga gaaatcaata gcatcgattg acatagcctc taatgcaaaa
    11641 tcaggagatc aaattgttgg tggtatagcc ggagttgttg agaaaagtgc gacaattaag
    11701 tatagctatg ttgaaggaaa tgttaacaat gtgcgacact ttggtaaagt tgggggagtt
    11761 gcaggtaatc tttgggatag agattcacaa gatgtaagta aatcaggtaa actatcatat
    11821 gttttaagtg atgtcaatgt tacgaatggt aatgctatag ctggctataa tttcaatgga
    11881 ataaaaacga ttgaaacata tagcaataaa aataataagg tagtaaacgt agtacaagaa
    11941 gatgatgagg ttgtgactaa agattcagat gtacaaagag gtacggtatt agatgctgat
    12001 aaagtaaaag agaaaaagat agaattggtt tctaaacaca gcactaaagt agaagatttt
    12061 gattttactt caagatacaa tactaattac a
//
LOCUS       DAVLHM010000054        11290 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLHM010000054 DAVLHM010000000
VERSION     DAVLHM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.054"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            713..1705
                     /locus_tag="VXE45_001822"
     CDS             713..1705
                     /locus_tag="VXE45_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0789816.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VXE45_001823"
     CDS             1707..2525
                     /locus_tag="VXE45_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0789817.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VXE45_001824"
     CDS             2527..3312
                     /locus_tag="VXE45_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789818.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="VXE45_001825"
     CDS             3351..3629
                     /locus_tag="VXE45_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0789819.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3614..3811
                     /locus_tag="VXE45_001826"
     CDS             3614..3811
                     /locus_tag="VXE45_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789820.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4237..4329)
                     /locus_tag="VXE45_001827"
                     /pseudo
     CDS             complement(4237..4329)
                     /locus_tag="VXE45_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4543..10962
                     /locus_tag="VXE45_001828"
     CDS             4543..10962
                     /locus_tag="VXE45_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0789821.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
BASE COUNT         3959 a         1683 c         2259 g         3389 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattgatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcatttcgtt ttttattgga ctataatagg
      601 ttggtataaa gccttttgta gtaataaaat gtagaaggtg tagaaagcaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccaa actcgctctt tcataagcgc atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattatg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtca
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattttt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagtta atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtaga ttttgtggtt ggtgtcttgg gagtctttct gactcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa gaaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactag atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtctt ggctttaaaa agttagagat ttttcctcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctt agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggatt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttac tcttagcggt tatttatatt gtttaatagc gctaatattt tatcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc
     4141 ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta ctgacttcgt cagttctatc
     4201 cacaacctca aaacagtgtt ttgagctgac tacgtcagtt ccatctacaa cctcaaaaca
     4261 ctgttttgag caatctgcgg ctagtttcct agtttgctct ttgattttca ttgagtacta
     4321 atcttatttt ttaatgtgtg ctaaaaaata aattaactaa tgttaatttt tttgacttaa
     4381 atttttttaa atgatatact gtttttatag agagataaca attatatata aatgtactac
     4441 tctatttcct agataatact tagtaaaact ttttataaca aaggctagca aagttaaagt
     4501 ttattatcta ttggaagtta tataaatatg taaggaatta aaatgaaaaa aagtacagta
     4561 ttgtcattaa ccacagctgc agttatttta gcagcctatg cccctaatga ggtagtctta
     4621 gcagacacat ctagctctga agatgcttta agcatctctg ataaagaaaa agtagcagaa
     4681 aataaagaga aacataaaga tattcataat gctatagaaa cttcaaagga tactgaagaa
     4741 aagaaaacaa caattattga ggaaaaagaa gttgttagta aaaatcctgt gatagacact
     4801 aaaactagca atgaagaagc aaaaatcaaa gaagaaaatt ccaataaatc ccaaggagat
     4861 catacggact catttgtgaa taaaaacaca gaaaatccca aaaaagaaga taaagttgtc
     4921 tatattgctg aatttaaaga taaggaatct ggatcaaaag caatcaagga actatccagt
     4981 cttaagaata caaaagtttt atatacttat gatagaattt ttaacggtgg tgctattgaa
     5041 acaactcaag ataatctgaa taaaattaaa caaatagaag gtattacatc ggttgaaagg
     5101 gcacaaaaag tccaacccat gatgaatcat gccagaaagg aaattggagt tgaggaagct
     5161 attgattacc taaagtctat caatgctccg tttgggaaaa attttgatgg tagaggtatg
     5221 gtcatttcaa atatcgatac tggaacagat tataggcata aggctatgag aatcgatgat
     5281 gatgccaaag cctcaatgag atttaaaaaa gaagacttaa aaggaactga taaaaattat
     5341 tggttgagtg ataaaatccc tcatgcgttc aattattata atggtggcaa aatcactgta
     5401 gaaaaatatg atgatggaag ggattatttt gacccacatg ggatgcatat tgcagggatt
     5461 cttgctggaa atgatactga acaagatatc aaaaacttta acggcataga tggaattgca
     5521 cctaatgcac aaattttctc ttacaaaatg tattctgacg caggatctgg gtttgcgggt
     5581 gatgaaacaa tgtttcatgc tattgaagat tctatcaaac acaacgttga tgttgtttcg
     5641 gtatcatctg gttttacagg aacaggtctt gtaggtgaga aatattggca agctattagg
     5701 gcattaagaa aagcaggcat tccaatggtt gtcgctacgg gtaactatgc gacttctgct
     5761 tcaagttctt catgggattt agtagcaaat aatcatctga aaatgaccga cactggaaat
     5821 gtaacacgaa ctgcagcaca tgaagatgcg atagcggtcg cttctgctaa aaatcaaaca
     5881 gttgagtttg ataaagttaa cataggtgga gaaagtttta aatacagaaa tataggggcc
     5941 tttttcgata agaataaaat cacaacaaat gaagatggaa caaaagctcc tagtaaatta
     6001 aaatttgtat atataggcaa ggggcaagac caagatttga taggtttgga tcttaggggc
     6061 aaaattgcag taatggatag aatttataca aaggatttaa aaaatgcttt taaaaaagct
     6121 atggataagg gtgcacgcgc cattatggtt gtaaatactg taaattacta caatagagat
     6181 aattggacag agcttccagc tatgggatat gaagcggatg aaggtactaa aagtcaagtg
     6241 ttttcaattt caggagatga tggtgtaaag ctatggaaca tgattaatcc taataaaaaa
     6301 actgaagtca aaagaaataa taaagaagat tttaaagata aattggagca atactatcca
     6361 attgatatgg aaagttttaa ttccaacaaa ccgaatgtag gtgacgaaaa agagattgac
     6421 tttaagtttg cacctgacac agacaaagaa ctttataaag aagatatcat cgttccagca
     6481 ggatctacat cttgggggcc aagaatagat ttacttttaa aacccgatgt ttcagcacct
     6541 ggtaaaaata ttaaatccac gcttaatgtt attaatggca aatcaactta tggctatatg
     6601 tcaggaacta gtatggcgac tccaatcgtg gcagcttcta ctgttttgat tagacctaaa
     6661 ttaaaggaaa tgcttgaaag acctgtattg aaaaatctta agggagatga caaaatagat
     6721 cttacaagtc ttacaaaaat tgccctacaa aatactgcgc gacctatgat ggatgcaact
     6781 tcttggaaag aaaaaagtca atactttgca tcacctagac aacagggagc aggcctaatt
     6841 aatgtggcca atgctttgag aaatgaagtt gtagcaactt tcaaaaacac tgattctaaa
     6901 ggtttggtaa actcatatgg ttccatttct cttaaagaaa taaaaggtga taaaaaatac
     6961 tttacaatca agcttcacaa tacatcaaac agacctttga cttttaaagt ttcagcatca
     7021 gcgataacta cagattctct aactgacaga ttaaaacttg atgaaacata taaagatgaa
     7081 aaatctccag atggtaagca aattgttcca gaaattcacc cagaaaaagt caaaggagca
     7141 aatatcacat ttgagcatga tactttcact ataggcgcaa attctagctt tgatttgaat
     7201 gcggttataa atgttggaga ggccaaaaac aaaaataaat ttgtagaatc atttattcat
     7261 tttgagtcag tggaagaaat ggaagctcta aactccaacg ggaagaaaat aaacttccaa
     7321 ccttctttgt cgatgcctct aatgggattt gctgggaatt ggaaccacga accaatcctt
     7381 gataaatggg cttgggaaga agggtcaaga tcaaaaacac tgggaggtta tgatgatgat
     7441 ggtaaaccga aaattccagg aaccttaaat aagggaattg gtggagaaca tggtatagat
     7501 aaatttaatc cagcaggagt tatacaaaat agaaaagata aaaatacaac atccctggat
     7561 caaaatccag aattatttgc tttcaataac caagggatca acgctccatc atcaagtggt
     7621 tctaagattg ctaacattta tcctttagat tcaaatggaa atcctcaaga tgctcaactt
     7681 gaaagaggat taacaccttc tccacttgta ttaagaagtg cagaagaagg attgatttca
     7741 atagtaaata caaataaaga gggagaaaat caaagagact taaaagtcat ttcgagagaa
     7801 cactttatta gaggaatttt aaattctaaa agcaatgatg caaagggaat caaatcatct
     7861 aaactaaaag tttggggtga cttgaagtgg gatggactca tctataatcc tagaggtaga
     7921 gaagaaaatg caccagaaag taaggataat caagatcctg ctactaagat aagaggtcaa
     7981 tttgaaccga ttgcagaagg tcaatatttc tataaattta aatatagatt aactaaagat
     8041 tacccatggc aggtttccta tattcctgta aaaattgata acaccgcccc taagattgtt
     8101 tcggttgatt tttcaaatcc tgaaaaaatt aagttgatta caaaggatac ttatcataag
     8161 gtaaaagatc agtataagaa tgaaacgcta tttgcgagag atcaaaaaga acatcctgaa
     8221 aaatttgacg agattgcgaa cgaagtttgg tatgctggcg ccgctcttgt taatgaagat
     8281 ggagaggttg aaaaaaatct tgaagtaact tacgcaggtg agggtcaagg aagaaataga
     8341 aaacttgaca aagacggaaa taccatttat gaaattaaag gtgcgggaga tttaagggga
     8401 aaaatcattg aagtcattgc attagatggt tctagcaatt tcacaaagat tcatagaatt
     8461 aaatttgcta atcaggctga tgaaaagggg atgatttcct attatctagt agatcctgat
     8521 caagattcat ctaaatatca aaagcttggc gagattgcag aatctaaatt taaaaattta
     8581 ggaaatggaa aagagggtag tctaaaaaaa gatacaactg gggtagaaca tcatcatcaa
     8641 gaaaatgaag agtctattaa agaaaaatct agttttacta ttgatagaaa tatttcaaca
     8701 attagagact ttgaaaataa agacctaaag aaactcatta aaaagaaata taaggaagaa
     8761 gacgactttg taactggtgg aaaaagaaca gtagaacttg attataaata tgacgataaa
     8821 ggaaatataa ctgcctatga agatgaaagt gctctagaat atgaaactga aaaatttgac
     8881 gaaataaaat caaaaattta tggtgttcta agcccatcta aagatggaca ctttgaaatt
     8941 cttggaaaga taagcaatgt ttctaaaaat gccaaggtat attatggaaa taactataaa
     9001 tttatagaaa tcaaagcgac taagtatgac tcacattcaa aaacgatgac atttgattta
     9061 tacgctaata ttaatgatat tgtggatgga ttagcttttg ctggagatat gcggtttttt
     9121 gttaaagatg atgatcgaat aaaagctgaa actaaaatta gaatgcctga aaaaaataag
     9181 gaaactaaag cagaatatcc ctatgtatca agttatggga atgtaatcga attaggagaa
     9241 ggagatcttt caaagaacaa accagacaat ttaactaaaa tggaatctgg taaaatctat
     9301 tctgattcag aaaaacaaca atatctgtta aaggataaca tcattctaag aaaaggctat
     9361 gcactaaaag tgactaccta taatcctgga aaaacggata tgttagaagg gaatggagtc
     9421 tatagcaagg aagatatagc aaaaatacaa aaggccaatc ctaatctaag agtcctttca
     9481 gaaacaacaa tttatgctga tagtagaaat gttgaagatg gaagaagtac ccaagctgta
     9541 ttaatgtcgg ctttggacgg ctttaacatt ataaggtatc aagtgtttac atttaaaatg
     9601 aacgataaag gggaagctat cgataaagac ggaaatcttg tgacagattc ttctaaactt
     9661 gtattatttg gtaaggatga taaagaatac actggagagg ataagtccaa tgtagaagct
     9721 ataaaagaag atggctccat gttatttatt gataccaaac cagtaaacct ttcaatggat
     9781 aagaactact ttaatccatc taaatctaat aaaatttatg tacgaaatcc agaattttat
     9841 ttaagaggta agatttctga taagggtggt tttaactggg aattgagagt taatgaatcg
     9901 gttgtagata attatttaat ctacggagat ttacacattg ataacactag agattttaat
     9961 attaagttga atgttaaaga cggtgacatc atggactggg gaatgaaaga ctataaagca
    10021 aacggatttc cagataaggt aacagatatg gatggaaatg tttatcttca aactggctat
    10081 agcgatttga atgctaaagc agttggagtc cactatcagt ttttatatga taatgttaaa
    10141 cccgaagtaa acattgatcc taagggaaat actagtatcg aatatgctga tggaaaatct
    10201 gtagtcttta acatcaatga taaaagaaat aatggattcg atggtgagat tcaagaacaa
    10261 catatttatg taaatggaaa agaatataca tcatttgatg atattaaaca aataacagac
    10321 aagacactaa acattaagat tgttgtaaaa gattttgcaa gaaatacaac cgtaaaagaa
    10381 ttcattttaa ataaagatac gggagaggta agtgaattaa aacctcatag ggtaactgtg
    10441 accattcaaa atggaaaaga aatgagttca acgatagtgt cggaagaaga ttttatttta
    10501 cctgtttata agggtgaatt agaaaaagga taccaatttg atggttggga aatttctggt
    10561 ttcgaaggta aaaaagacgc tggctatgtt attaatctat caaaagatac ctttataaaa
    10621 cctgtattca agaaaataga ggagaaaaag gaggaagaaa ataaacctac ttttgatgta
    10681 tcgaaaaaga aagataaccc acaagtaaac catagtcaat taaatgaaag tcacagaaaa
    10741 gaggatttac aaagagaaga tcattcacaa aaatctgatt caactaagga tgttacagct
    10801 acagttcttg ataaaaacaa tatcagtagt aaatcaacta ctaacaatcc taataagttg
    10861 ccaaaaactg gaacagcaag cggagcccag acactattag ctgccggaat aatgtttata
    10921 gtaggaattt ttcttggatt gaagaaaaaa aatcaagatt aagataaaag ctatagaaaa
    10981 aaatggttta tgtactgaga ttagatagtg aggtgatgac atagttttgt gaaaacagcc
    11041 atttataact caattattta gtttacttca ctattgatac tatttggagt tattaatgga
    11101 cttagtttag ataactaatg aattgattga aagggttagt attgacaata ttggtcatat
    11161 tgattagaaa atagagtcta tcaaaattta aaggctaata gaggtgatga gacaatttcg
    11221 gctctttgtc aactgtagtg ggttgaagtc agctaagctc gagaaaggac aaattttgtc
    11281 ctttcttttt
//
LOCUS       DAVLHM010000055        11134 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLHM010000055 DAVLHM010000000
VERSION     DAVLHM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.055"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            56..418
                     /locus_tag="VXE45_001829"
     CDS             56..418
                     /locus_tag="VXE45_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789822.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            953..1645
                     /locus_tag="VXE45_001830"
     CDS             953..1645
                     /locus_tag="VXE45_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0789823.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1698..4108
                     /locus_tag="VXE45_001831"
                     /pseudo
     CDS             1698..4108
                     /locus_tag="VXE45_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
     gene            4358..5059
                     /locus_tag="VXE45_001832"
     CDS             4358..5059
                     /locus_tag="VXE45_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789824.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDVLNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5061..7769
                     /locus_tag="VXE45_001833"
     CDS             5061..7769
                     /locus_tag="VXE45_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0789825.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7865..8356)
                     /gene="tpx"
                     /locus_tag="VXE45_001834"
     CDS             complement(7865..8356)
                     /gene="tpx"
                     /locus_tag="VXE45_001834"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0789826.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8479..9408)
                     /gene="psaA"
                     /locus_tag="VXE45_001835"
     CDS             complement(8479..9408)
                     /gene="psaA"
                     /locus_tag="VXE45_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0789827.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9440..10288)
                     /locus_tag="VXE45_001836"
     CDS             complement(9440..10288)
                     /locus_tag="VXE45_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0789828.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10285..11007)
                     /locus_tag="VXE45_001837"
     CDS             complement(10285..11007)
                     /locus_tag="VXE45_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0789829.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3277 a         2074 c         2537 g         3246 t
ORIGIN      
        1 aaaagcaaat atgatacaat tttatttgaa aaaaaataaa aaaggagatt ttattatgaa
       61 atcaagtggt atcgtcggtc ttgtgggagg aattttactt cttatttgtc cttttgtctt
      121 gttgggaaca gcggtaaaca cagctgctac aactcttaat ggaggagcta ctgcaggggc
      181 tttttcaggt gttgccttac tcttgaatgc cttgaagatt gcaaatcttg ttcttggtat
      241 cattgctatt gtttactata aaggagataa gcgtgtaggt gcagctccgt ctgtactaat
      301 gattgtttct ggtgaagtta gtctcattcc attcttagga tgggttgggg ggattcttgc
      361 tattatcgga ggatctctat tccttgcaac attgaagaaa ttcaaatcag aagaataaaa
      421 ggtattttag catgaaaaga acaaaaaagt ttatcggtat aggagtagct ctattatctc
      481 tttctcttct agttgcatgt ggaacataaa gttcaaagaa tacttcaaca agtaatgatg
      541 agaagacagt agcaacatcc aatagttcaa aagaaacaat cactttcgat acaccggttg
      601 taacagacga tgcgattgaa tcaatacgca cttatgcaga ttatatagat ctttataaaa
      661 atatttttga tgattatttt actaaaactg aggaaggttt caaaggcaca gctatggaaa
      721 ataatgactc gtttactaaa ctaaaagagt caactcaaaa attattcgat gcgcagaaaa
      781 aaaggttaaa taatgaagat agaatagaaa caaccaaaaa caatgtgatt gccaaacatt
      841 gtcaaacagt cctttccttt ttggttttga ctagcttttt tgtgaaaaat tgtgtaaaat
      901 agaatagata aacgagggga aacctcggaa aatttaaagg agaatccatc taatggtaaa
      961 attggttttt gctcgccacg gtgagtctga atggaacaaa gctaaccttt tcactggttg
     1021 ggctgatgtt gatttgtctg aaaaaggtac acaacaagcg attgacgctg gtaaattgat
     1081 caaagaagct ggtatcaaat ttgaccaagc ttacacttca gtattgaaac gtgctatcaa
     1141 aacaactaac ttggctcttg aagcttctga ccaattgtgg gttccagttg aaaaatcatg
     1201 gcgcttgaac gaacgtcact acggtggttt gactggtaaa aataaagctg aagctgctga
     1261 acaatttggt gatgagcaag ttcacatctg gcgtcgttca tacgatgtat tgcctccaaa
     1321 catggaccgt gatgatgagc actcagctca cacagaccgt cgttacgctt cacttgacga
     1381 ctcagttatc ccagatgctg aaaacttgaa agtgactttg gaacgtgctc ttccattctg
     1441 ggaagataaa atcgctccag ctcttaaaga tggtaaaaac gtattcgtag gagctcacgg
     1501 taactcaatc cgtgcccttg taaaacacat caaaggtttg tcagatgacg agatcatgga
     1561 cgtggaaatc cctaacttcc caccattggt attcgaattc gacgaaaaat tgaacgtcgt
     1621 ttctgaatac taccttggaa aataaaaaat tgtaagtcta gaattgattt ctaggctttt
     1681 tatgttagta tggaagtatg ataaggaata aaaaacaaga ttatgtactg gcctacaagc
     1741 aaccagcttc aaccacttac atgggttggg aagaagaagc tttaccgata ggcaatggtt
     1801 ctttaggagc aaaagtattt ggccttatag gggctgaacg gattcaattt aatgaaaaaa
     1861 gtctctggtc tggaggtcca cttcctgata gttcagatta tcagggtgga aatcttcagg
     1921 atcagtatgt tttttagctg agattcggca ggctttggag aagagagatt acaatctggc
     1981 taaggaactg gctgagcagc acctaattgg gccaaaaacg agtcaatatg ggacctatct
     2041 gtcttttggg gatattcaca ttgagttcag ccagcaaggt acgactttgt ctcaggtgac
     2101 ggactatcag agacagctga atattagtaa ggcacttgcg acgacttctt atgtctataa
     2161 gggaacgcga tttgaacgtg aagcttttgc gagttttcca gatgatctct tggttcaatg
     2221 ttttactaag gaagggttgg aaactctaga ttttactata gaactatcct tgacctgtga
     2281 tttggcttct aatggaaagt atgaacagga aaagtctgat tacaaggagt gtaagttgga
     2341 tattactgat tctcatatct tgatgaaggg aagagttaag gataatgatc tgcggtttgc
     2401 tagttatcta gcttgggaaa cggatggaga tattagagtt tggtcatata gggttcagat
     2461 atcaggagcc agttatgcca atctcttctt ggccgctaag acggattttg cccaaaatcc
     2521 tgctagcaat tatcgcaaga aactagattt agagcaacag gtgagagact tggtggacac
     2581 agctaaagaa aagggctata cccaattgaa atcaaggcat atcgaggact accaagcctt
     2641 attccagcgt gttcaattgg atttggaagc tgatgttgac gcatccacta cagatgattt
     2701 gttaaaaaat tataagccac aagaagggca ggctttggag gagctgttct tccagtatgg
     2761 acggtattta ttgattagtt cgtccagaga ctgcccagat gctctaccag ctaacctaca
     2821 gggagtctgg aatgcggtcg acaatcctcc ttggaattcg gactatcact taaatgtcaa
     2881 tctgcagatg aattattggc cagcctatgt taccaatctc ctagaggcgg tctttccggt
     2941 catcaactat gtagatgatt tgcgtgtcta tggtcgtcta gcggctgtaa agtatgcagg
     3001 aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt catactcaag cgactccctt
     3061 tggttggacg gcacctggtt gggattacta ttggggttgg tcaccagctg ccaatgcgtg
     3121 gatgatgcaa accgtttatg aagcctattc attttatagg gaccaagact atctcagaga
     3181 gaaaatttat cccatgttga gggaaacggt tcgtttttgg aatgcctttt tacataagga
     3241 tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc ccagaacatg ggccgatttc
     3301 gattggcaat acttatgacc aatctctaat ttggcagtta tttcatgatt ttattcaggc
     3361 tgctcaggaa ttgggactgg atgaggactt gttgactgag gttaaggaga agtctgattt
     3421 actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg gagtggtatg aggaggaaga
     3481 gcagtatttt caaaatgaga aagtggaggc ccagcatcgg cacgcttccc atctagtggg
     3541 actctatcct ggcaatctct ttagctacaa gggacaagag tatattgaag cggcgcgtgc
     3601 tagcctcaat gatcgtggag atggcggcac aggctggtcc aaggctaata agatcaatct
     3661 ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta ttggcagagc agttaaagac
     3721 atccaccttg ccaaatcttt ggtgtagcca tcctcctttt cagatagatg gtaattttgg
     3781 tgctactagt ggcatggcag aaatgttact ccagtctcat gcagcttatc tggtacctct
     3841 agctgcccta cctgatgctt ggtcaacagg ttctgtttca ggcttaatgg cacgtggaca
     3901 ttttgaagtg agcatgagct gggaagataa aaaactctta cagttgacca ttttatcaag
     3961 gagtggagga gatttgcgag tttcttatcc agatattgag aagagtgtga ttaaaatgaa
     4021 tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt atttcggtgg caacagcaga
     4081 aggtgatctt gttcaatttt atttttaaga agatgttata aggcagtaat ttgaaactgc
     4141 cttttaataa ggatttaaga atataagcag ttttcaacta gttgaaaaag cgttataatg
     4201 ataataggaa gtaatactca atgaaaatca aagagcacaa acaaggaagc tagccgcagg
     4261 ttgctcaaaa cagtgttttg aggttgcaga tggaagctga cgtggtttga agagagattt
     4321 tcgaggagta taatttgttt gatagagggt gggtctgatg gcttatattg agatgaaaca
     4381 ctgttacaag cgttatcagg ttggggacac ggagattgtg gccaatcgtg atgtgaattt
     4441 tgagattgaa aagggggagc tggttattat ccttggtgct tcaggtgcag gcaagtcaac
     4501 agtgcttaac cttcttgggg gaatggatac caatgatgaa ggggaaatct ggattgatgg
     4561 tgttaatatt gcggattata gttcccacca gcgcaccaat taccgtagaa atgatgtggg
     4621 gtttgttttt cagttttata atctagtttc taatctgaca gctaaggaaa atgtggaact
     4681 ggcttctgaa attgtgacag atgtcttgaa tcctgatcag gtcttgacag atgtaggtct
     4741 ggctcatcgt ctaaataact ttccagccca gctttctgga ggggagcaac agcgagtctc
     4801 cattgcacgc gcggtagcca aaaatcctaa aattcttctt tgtgatgaac ctactggagc
     4861 cttggattat cagacgggca agcaggtttt gaaaattctc caagatatgt ctcgtcaaaa
     4921 gggagcgacg gtgatcatcg tgactcataa tggagctttg gcgcccattg ctgatcgcgt
     4981 gattcatatg cacgatgcca gtgtcaagga tgtggtgctc aaccagcatc ctcaggatat
     5041 tgacagtttg gagtactagt atgatcaagc gaaaaactta ttggaaggac ttaattcagt
     5101 ccttcacagg ctccaagggg cgttttttat ccatcttgat cctgatgatg ttgggatctc
     5161 tagccttagt aggcctcaaa gtaaccagtc ccaacatgga ggcgacagct aatgcttatt
     5221 taacaactgc tcaaaccttg gatttggcag tcatgtctaa ctatggcttg gatcaagcag
     5281 accaagaaga actaaaacag acggagggcg cagaggtcga gtttggctat ttgacagatg
     5341 tgactatgga taatgggcag gatgccattc ggctgtactc caaaccagag cgaatttcaa
     5401 cctttcagct aagaaaggga cgacttcctc agtcagacaa ggaaatcgct ttggccactc
     5461 atttgcaagg ccaatgcagc gtgggacagg agattagttt taaagaaaaa gaagagggtc
     5521 attcctcttt aaaagaccat acttatacca ttactggttt tgtggattcg gctgaaatcc
     5581 tctcccagcg agatatgggc tacgcaggaa gtggaagtgg gactctgaca gcctatgggg
     5641 tgattttacc tagtcagttt gatcagaaag tctacaatat agctcgtttg aaatatcaag
     5701 atttagcagg tttaaatgcc ttttcatcag cttatgaaga aaaatccaag caacatcagg
     5761 aagaccttga acaaacttta tcagataatg gcaaggtacg tctgcaactt ttgaaaaaag
     5821 aaggacaaga gtctctagac aaggggcaag agacccttga caaggctcag actaatttgc
     5881 aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat acaggctcaa gaaagtcaac
     5941 tagccttgtt tcctcaagtt cagagagagc aggctagtgc tcaacttacc caagccaagc
     6001 aggaattggg caaggaagaa gacaaactaa agcaagctga acaaaatcta gcccaagaaa
     6061 aggaaaaatt agaaaaacat cagcaagtct tggacgattt ggcggagcca aggtatcagg
     6121 tctataatcg tcagaccatg ccaggtggtc agggctatct tatgtatagc aatgcttcat
     6181 ccagtattcg agcagtgggc aatatctttc ctgtggtact ttatgccgta gcagccatgg
     6241 tgacctttac gaccatgact cgctttgtag acgaagagcg aactcatgca gggattttta
     6301 aggccttggg ttaccgtagt aaggatatta tcgccaagtt tctcctttat ggactagtag
     6361 ctgggactgt cggaacggct ctaggtagta tacttggtca ttatttgcta gccagtgtaa
     6421 tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac ccagattcag ttctattgga
     6481 cctatagctt actagctctt gtcttgagct ggttggcgag tgtgttacca gcctatctgg
     6541 tggcttggag ggaacttcat gccgaagcag cccagcttct acttcctaaa cctcctgtca
     6601 aaggagctaa aatcttattg gagcgtatcg gttttatctg gcgtcgtctc agttttactc
     6661 ataaggtaac agcccgcaac atctttcgtt ataagcagag aatgttgatg acaatctttg
     6721 gtgtggcagg ttctgtagct ctgctctttg caggtttggg aatccaatct tctgtagcag
     6781 gagttccgtc taaacagttt caacaaatcc aacagtatca gatgcttgtc tctgaaaatc
     6841 ctagtgcgac cgatcaggac aaggtagagc tagcagaagt gttgaaaggg caggagatac
     6901 tagcctacca gaaaatctat tctaaaacgc tagacaagga tttcaaaggc aaggctggtc
     6961 ttcaaaacat tactcttatg atgatagaga aggaagattt gactcccttt atccatcttc
     7021 aacatcatca gcaggagctg acattaaaag atggcatcgt tattacagct aaactcgccc
     7081 agctggcagg tgtcaaggtt gggcagactt tagaaattga aggtaaggaa ctaaaggtcg
     7141 ctgctattac tgagaactac gttggtcact ttatttatat gagtcaggct agctatgagc
     7201 aactttacgg acagctaccc caagccaaca cttatctggt ctcattaagg gataccagtg
     7261 caactagtat cgaaagtcag gcgggcttgc ttatgagtca atctgcggtg tccagcgttg
     7321 tccaaaatgc ttcagccatt cgactcttcg actctgtcgc tagctcactc aatcagacca
     7381 tgaccatctt ggtcatcgta tcggttctat tagctattgt catcctttac aatctgacca
     7441 atatcaacgt agctgagaga atccgtgaac tctccactac caaggttctt ggttttcata
     7501 ataatgaagt caccctctac atttaccgtg agacgattgt gctatccctt gtgggaatcg
     7561 tacttggtct ggtagctggt ttctatttac accaattttt gattcaaatg atttcgcctg
     7621 cgactattct cttttatccg caggtaggct gggaagtcta tgtaatccca gtggcagcag
     7681 taagcatcat tttgaccttg cttggtttct tcgtcaatta ttatctgaga aaggttgata
     7741 tgttagaagc cctgaaatct gtagagtaag gtagttattt ttagctgatt gaacttctat
     7801 ttactaatat tcaaaaatcc tccgtttcaa agagcaggga actctttgtg acagaggatt
     7861 ttttctatag ggctttagca gctgcaattg cggcttcgaa gtttggctca gaattgatat
     7921 tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc gaggacaaag actgcgcgtg
     7981 ctaataggtg ccattcgttg atcaagaggg cataatcgcg cccgaaagaa tggtcaaagt
     8041 agtctgaaag cataatggca ttgtcaaggc cttcagcacc gcaccaacgt ttttgagcaa
     8101 aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc cagtccagcc aattcttcat
     8161 taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat agaaggaacg acactcaaga
     8221 cttttttctt gccatcaaaa tcagccagag attttttaga aagatctgtt gtagtaagag
     8281 aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc tgtaaagctc acaggatttc
     8341 cgagaaaagt taccatagga tactccaatc ttttttcttc cattgtatct gaaacagtca
     8401 gaattttcca atgatttgac cggaaatgtg ggcatagaaa aaacgccagc tcacatgaga
     8461 atgacgtttt tcagaggctt attttgccaa tccttcagca atcttgtcaa ggttgtattt
     8521 catcatgctg tagtagctgt cgccttcttt accttgttct gcgatagagt cagtaaagat
     8581 ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt ttcattggac ggtcatccac
     8641 acttgattct acaaagagtg atggaacttt tgtttggcga agtttttcaa ccaaggtctt
     8701 gatttgttca ggagttcctt cttcttcagt attgatttcc cagatgtagg cacttgggac
     8761 accataggct ttagagaagt atttgaatgc tccttcgctg gttacaatga gtttcttttc
     8821 agcagggatc ttattaaatt tatccttact ttctttatca agtttgtcta acttatcagt
     8881 atattctttg agattttttt catagaattc tttattgtta gggtctttgg cgctcaattg
     8941 tttggcgata tttttagcaa aaataatacc gttttcaagg ttaagccaag cgtgtgggtc
     9001 ttcttttcct ttttcatttt gaccttcaag gtagataaca tcaacgccgt cgctgactgc
     9061 gaagtagtct ttgttttcag ttttcttggc attttctacc aattttgtaa accaagcatt
     9121 gccacctgtt tcaaggttga taccgttata gaaaatcaaa tcagcctcag aagttttctt
     9181 aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc ccaatcggaa cgatactatg
     9241 aaggtcaatt ttgtcaccag caatattttt agtaatatca gcgatgattg agtttgtagc
     9301 aacaactttt agtttttgac cagaagttgt atcttttttt ccgctagcac atgctacaag
     9361 aatgattgca gaaagaaaga gaacgagtaa tgtacctaat tttttcatta gatcctccaa
     9421 tttattaggg ctttgcccct tattttaaca aatgtttatt tttcagtttc aaatatcgtt
     9481 gtttgggagc gataaagaag ctaatgagaa agaaactagc agctgtaagc acgatactag
     9541 aacctgccgc aacattaaaa ctatagccaa taaagagtcc caaaactgaa gcagtagctc
     9601 cgaaggttga ggaaaggaaa atcatgcttt tcagactatt agcatacaga taagcagttg
     9661 cagctggggt aatcagcatg gctacaatca ggatagttcc gacactttgc atggctgtca
     9721 cagacacgag agtcaggagt accatgagaa ggtagtgata gaaattgaca ggcattccca
     9781 tggctttagc caagagttca tcaaaggaag ttatcaagag ttgcttgaag aaaatccaga
     9841 ttaacaagag gatggctgcc cccacaccca tagtaataaa catatccgta tcttggacgg
     9901 ccaggatatt accaaaaagg atatggaaaa ggtcagttga acttttagcg acaccaatca
     9961 agatgatacc gagggctaag aaagaagaaa aggtaatgcc gatggcggta tcgcttttga
    10021 taatcgagtt tcctttgatg taggtaatga tgatggcagc tagcaatcca aagacaatgg
    10081 ctccgataaa gaagtcaagg cccaagatga aggagagggc tacacctggt aagacagcat
    10141 gtgaaatggc atctcccatg agtgacatcc cgcgtagaat aatgaaacat cccacggctc
    10201 cagctacaat cccgacgaca atagctgtta tcaaggcatt ttgtaggaaa tggaattttt
    10261 gcaatccatc gataaattct gcaatcatag gtcacctcca ttgaaaaaga gttgattacc
    10321 gtaagcttct tttagattgg tttcggtaaa agtttctttt gttggaccaa aggcaatcac
    10381 ttctcgattg acaagtaaga cttgatcgaa gtagtgggga atcttgctga ggtcgtggtg
    10441 aacgatgaga accgtcttcc cagctttttt caaatctctc agcgtattca tgatgatttc
    10501 ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag aggatatagt cggcttcctg
    10561 caccaaacat ctggcaatca agacccgctg gaattgacct ccagacagtt gactaatttg
    10621 acgttcagcg tagtcagcta ggccgacgat ttcaagggcc tcttgcactt tcttccaatg
    10681 tttagccttt aaacttcgaa agagaggaat agagggaaat agtcctaacg agacgcattc
    10741 cttgaccttg atgggaaagt tgtagtcgat attgattttt tgttcgacat aggcaattcg
    10801 gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc tgaccttgat gtgggataat
    10861 tcccaacata ccttttaata gtgttgattt cccagcgccg tttggaccaa tgatgccggt
    10921 aattgttggt ccatggagca ctagtgaaat atccttaagt gccaacgttt ctttgtagga
    10981 gacactgagg ttttcgatac gtatcataaa cttgtattcc tcctgtctct taatatacat
    11041 taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta aaataataac tgaaaaatag
    11101 attctaaaaa taactttcag gataaatttc taaa
//
LOCUS       DAVLHM010000056        10758 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLHM010000056 DAVLHM010000000
VERSION     DAVLHM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.056"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(117..1541)
                     /locus_tag="VXE45_001838"
     CDS             complement(117..1541)
                     /locus_tag="VXE45_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0789830.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="VXE45_001839"
     CDS             complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="VXE45_001839"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0789831.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPYGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="VXE45_001840"
     CDS             complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="VXE45_001840"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0789832.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERGNLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6528..7706)
                     /locus_tag="VXE45_001841"
     CDS             complement(6528..7706)
                     /locus_tag="VXE45_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0789833.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGFIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSIHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7786..8649)
                     /locus_tag="VXE45_001842"
     CDS             complement(7786..8649)
                     /locus_tag="VXE45_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0789834.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYFFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8652..10553)
                     /locus_tag="VXE45_001843"
     CDS             complement(8652..10553)
                     /locus_tag="VXE45_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0789835.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSKKTSGNVVLTVENTAI
                     GYDGEVLSQPINVDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3231 a         2368 c         1910 g         3249 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaattcct
      181 tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt ctctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg taaataagcc gcacgttcaa ctgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc aaaatttttg
     1621 agattatttt cacaaacttg atttttcaaa gtatactcaa taaaaataaa aaaaatccac
     1681 tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
     1741 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagccaaacc aatttctcac
     1801 aatgtttcag aaacaagggt gtgctactcc aatttcagcc tactataact gtcatagatt
     1861 gctgaaacaa agtctaggta aaagtcttca taataaaaag acctcctatc aagtgttcaa
     1921 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
     1981 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt actaatactc
     2041 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
     2101 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttaccaa
     2161 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
     2221 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
     2281 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaagg caccagtttt
     2341 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
     2401 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
     2461 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
     2521 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
     2581 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
     2641 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     2701 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     2761 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     2821 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     2881 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     2941 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     3001 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     3061 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     3121 ggtaccatat ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     3181 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     3241 ataagcttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     3301 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     3361 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     3421 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     3481 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     3541 tttagtcaaa tcacgaatat gcatttcaca gataactgcc ttacatggat tttccaagcg
     3601 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     3661 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     3721 tgtttggtga tgagggaatt ggacttgata ctgataagcc ttacctacca aatcttcctc
     3781 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     3841 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     3901 aacttgcact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     3961 acggcaaccc aattctcctt ggtaacccca atgatggtca aaactagcac tgttaatggc
     4021 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     4081 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     4141 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     4201 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     4261 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     4321 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     4381 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     4441 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     4501 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     4561 taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac ccagactttc
     4621 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     4681 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     4741 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     4801 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     4861 atacagattt tcaattgaat ggaaatattg aagtaaaagc tgactagcct tgcttccgac
     4921 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     4981 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     5041 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     5101 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     5161 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     5221 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     5281 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     5341 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     5401 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     5461 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     5521 agcagggaac ttgtaggcta ctgcccactt tggagcctta acggtaaaac caagttcttc
     5581 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gcagatttcc
     5641 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     5701 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     5761 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac gcttggcaac
     5821 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     5881 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     5941 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     6001 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     6061 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     6121 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     6181 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     6241 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     6301 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgaaaccga
     6361 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     6421 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     6481 gcggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     6541 tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac accacttcca
     6601 attatcagga aagaagagag atgtatactt ggcaagactg tcataaatcc ttttgcaata
     6661 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctcttccaag aaattcgctc
     6721 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     6781 caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     6841 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     6901 gctagaagag ccccaatgat gaaaccaata gcccccatag ttaaaatact tgcataggct
     6961 ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     7021 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     7081 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     7141 acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa aaaagtcagc
     7201 gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa ggaaagaaca
     7261 ggagagctaa cacctacaac ctgcaaaacc agctctaagc gagaattata gatcacaatc
     7321 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     7381 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     7441 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     7501 cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgagaat agatgtgacg
     7561 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaac
     7621 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     7681 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     7741 tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     7801 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     7861 atgtatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     7921 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     7981 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct ctaaacaatg
     8041 ctggtaacaa ttgagggcca aaatcaaaac taatctctta tggcgactaa tctcttggta
     8101 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     8161 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagaa
     8221 ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat ctctttgaca
     8281 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa aggggagtcg tcgaactctt
     8341 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     8401 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     8461 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     8521 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     8581 tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata cttttccaag
     8641 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     8701 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     8761 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     8821 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     8881 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     8941 ctcatttctg ctgttgctct cttctcaata tagtagtcgt aatctccaag gtagagagtt
     9001 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     9061 tgactgacaa aaagcaaggt accatcaaag tcaatcaagg cattttctag cacttcctta
     9121 ctatcaatat ccaagtggtt ggtcggctca tccagaatca aaaagttatt gttttccata
     9181 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     9241 ttaacatcat ctcctgagaa aaggaaggct ccaagacggt tgcggatttc aacttctggt
     9301 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     9361 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc tcccttgata
     9421 aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc atttggacca
     9481 acgatagcga cagcattcat cttacgaaga tctacgttaa tcggttgtga caggacttcc
     9541 ccgtcataac caatagcagt attttcaaca gtcaaaacaa cattgcccga cgttttttta
     9601 gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa acgctccatt
     9661 ttttctagtt gtttacggcg agattgagca cgtttagtcg ttgaagcacg aactagattg
     9721 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     9781 tcagtagcta gcttttgctc cttcaattcg acaaaacgag agtaattccc cacatagcga
     9841 tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     9901 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggcg
     9961 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
    10021 aggagcattt tagctagagc caaacgagta ttttgaccac ctgaaagttc agctattttc
    10081 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
    10141 taggtaaagc cgcctgcttg gcgaaaattc tcagataagt ggtcgtaatc tgacatcagt
    10201 ttatccaatt catcgccaga cttttcaccc atctccaact ccatctgacg aagttgttta
    10261 tctgtccgac gtaagtcatc aaagacatga agcatctcat catagatggt attttcagac
    10321 tcaaaacggc tatcttgagc taggtaagac agagaaatat cttttttctt attgatttct
    10381 ccactagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt acctgcacca
    10441 tttttcccaa caagggcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
    10501 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat catacaagta
    10561 gtatagcatg tttccctaag tcattcaaga taatcgtaag tcttttagta caacttttat
    10621 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
    10681 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagcctatta tttaattctt
    10741 ttcattattt acgtacgc
//
LOCUS       DAVLHM010000057        10602 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLHM010000057 DAVLHM010000000
VERSION     DAVLHM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.057"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            239..577
                     /locus_tag="VXE45_001844"
     CDS             239..577
                     /locus_tag="VXE45_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV0789836.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            767..2203
                     /locus_tag="VXE45_001845"
     CDS             767..2203
                     /locus_tag="VXE45_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0789837.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2255..2493
                     /locus_tag="VXE45_001846"
                     /pseudo
     CDS             2255..2493
                     /locus_tag="VXE45_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
     gene            2623..2937
                     /locus_tag="VXE45_001847"
     CDS             2623..2937
                     /locus_tag="VXE45_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV0789838.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3055..5034
                     /locus_tag="VXE45_001848"
     CDS             3055..5034
                     /locus_tag="VXE45_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0789839.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5044..5358
                     /locus_tag="VXE45_001849"
     CDS             5044..5358
                     /locus_tag="VXE45_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV0789840.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5389..5895
                     /locus_tag="VXE45_001850"
     CDS             5389..5895
                     /locus_tag="VXE45_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789841.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5975..7321
                     /gene="celB"
                     /locus_tag="VXE45_001851"
     CDS             5975..7321
                     /gene="celB"
                     /locus_tag="VXE45_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV0789842.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVIIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDVFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7701..7877
                     /locus_tag="VXE45_001852"
     CDS             7701..7877
                     /locus_tag="VXE45_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789843.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8278..10491
                     /locus_tag="VXE45_001853"
     CDS             8278..10491
                     /locus_tag="VXE45_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0789844.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSKTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAIPLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
BASE COUNT         3550 a         1429 c         2109 g         3514 t
ORIGIN      
        1 atatcaaaaa gcacctcaaa aaggtattac caagttgcca taccttttat gaggctcttt
       61 tgtcttgttc ttgtttcaat tgactataaa tcgctataag aaaaaatcat tttattggta
      121 taaagaagtg attgaaagta atggcaaaac gttagataat tagttcataa aaaacaagtt
      181 tagatcctca tctaaacttg tttttttaaa attgaaggat gattttggag gatataagat
      241 gacattgact attcatgtat attataaagg tgatggagat agtgcaataa agtttgcaag
      301 agaaatgctt gatagtggcc ttgttgaaga aattagaaat caaaaaggta acttgaaata
      361 cgaatatttt ttaccaattg aaaaagaggg aactattctc cttattgatc agtggataaa
      421 tcaagaaact ttagataaac attatcaatc aaagacaatg cagaaaatct tagatttaag
      481 aaaaaaatat cacttgcaga tgcaagttga acgttatata gaagatgatt ctgggatgcc
      541 agaaagcgat aagtcgttta tagacacagg gaattagaat tattgtgaga gtttttgtag
      601 tttgaaagta ttgaaaatcg taaagatatc attacgagaa tacaagaaga tattgttcta
      661 tttccattaa aaattacttc tttccttaac aataaggaaa aagaatacgt tttcattttt
      721 tggtttgagg tttataataa gagtatcaaa gtcaggagga aaaaagatga ctacttttaa
      781 agatagattt ttatggggtg gtgctgttgc tgctcatcaa cttgaaggcg gatggcaaga
      841 aggtggcaaa ggaattagtg ttgctgatgt tatgactgct ggtcgtcatg gagtagctcg
      901 tgaaattact tcgggagttt tagagggtaa atattatcca aatcatgagg cgatagattt
      961 ttatcatcgt tataaagaag acatagcact ttttgctgaa atgggattca agtgcttccg
     1021 tacctctatt gcatggacac gtatctttcc aaaaggtgat gagttagagc cgaatgaaga
     1081 aggattacag ttttatgata atctttttga tgaatgctta aagaatggta ttgaacctgt
     1141 catcactcta tctcattttg aaatgcctta tcacttagtg accgaatatg gtggttggaa
     1201 aaataggaaa ttgattgatt tctttgctcg ttttgcagaa gtcgtattta aacgttacaa
     1261 agataaggtt aaatattgga tgactttcaa tgaaatcaat aatcaagcga attatcagga
     1321 agattttgca ccatttacta actcaggtat tgtatatgag gaaggtgata atagagaagc
     1381 aattatgtat caagcagcac attacgaact agttgcttct gcacgagctg taaaaattgg
     1441 tcatgagatt aatccagatt ttcaaatagg ttgtatgatt gcgatgtgtc caatttatcc
     1501 agctacttgc aatcctaagg atatcttaat ggcaatgaaa gctatgcaga agcgttatta
     1561 ttttgctgat gtgcatgttt taggtaaata tcctgagcat attttcaagt attgggaacg
     1621 aaaaggtatt tcagttgatt ttactgacca ggataaagaa gatttacttg gtgggactgt
     1681 agattacatt ggtttcagtt actatatgtc ctttgctata gactctcatc gtgaaaataa
     1741 tccttatttt gattatcttg aaacagaaga tttagtgaaa aataattatg ttaaggcttc
     1801 tgaatgggag tggcaaattg atccagaagg tttacgttat gcgttaaatt ggtttacaga
     1861 ccactatcac ttaccactct ttattgttga aaatggtttt ggagctatag atcaagttgc
     1921 agcagatggt atggtacatg atgattatag aattgaatat ctaggtgccc atattcgtga
     1981 aatgaaaaag gctgtagttg aagatggtgt tgatttaatg ggttatactc catggggatg
     2041 tattgatttg gtttcagctg gtaccggtga aatgcggaaa cgttatggtt ttatttatgt
     2101 agataaagat gacaatggga agggaagtta taatcgttcc ccgaaaaaat cttttggctg
     2161 gtataaggaa gttatttcat ctaacggtga atcagtagaa tagtataaac aaactgagat
     2221 tattctcagt ttgtttagca tattgggatg acatatgatt ggaagtattg cagcaatttt
     2281 aacaacattt gctttttacc acaagttttt cgtatagtta agacaaagga cacaggatct
     2341 attgctctag gtatgtatgt tatgcaagtt attgatattg cattgtggct tgctcatggt
     2401 attcgtatag gagacttgcc tttgatttta gcaaatagtg tttcatttct actctcagga
     2461 ataattttat tttataaatt gaagtataaa taattttttt ccatatcatt taggaaaatg
     2521 agggaattgt cattggaaac gctttatttt ataataaaaa tagataacag ataagtcaac
     2581 ttagcacagc tttgattgga tttaagaaaa ggagaaaata ttatggcaaa agctttaatt
     2641 atttgtgcag caggaatgtc ttcatcactt atggcacaga aaacaacaga gtttctaaaa
     2701 ggaaaaggga aagatattgt agttgatgct attagtgcta ctgaaggagg gaaagctatc
     2761 gcagcagcag cttttgattt gtatcttgtc agccctcaaa caaaaatgta ctttaagcaa
     2821 tttgaagagg ctggttctaa agcaggaaaa ccagttgtac aaatacctcc tcaagcctat
     2881 attcctattc caatgggaat tgaaaaaatg gctaatttga ttcttgagaa tatttgatga
     2941 acacatgaaa tgtcaataaa tatttaagtt aagataaatt gttttgagtt tgatataaat
     3001 tgatttaagt gtataatatg cttcaatata tgaaaacata cgttttagga gggaatgaat
     3061 gtgttaaaca ttaaagagaa agatatcctt caatttttaa taaaaaataa ggaacgtttt
     3121 gttacaagca aagaactggc agaatattta tcctgttcag atagaactgt ccgtaatgta
     3181 ctgaaattaa ttgagaagac aatgattatt caaggagtcc ggttgatttc aaaacaaggt
     3241 caagggtatc aaatattttt tgagaatcaa ggcgcttacc aggagtttag acaaacttat
     3301 gaactggaag aagactatac gaaaactgcg gtttcaaaag gtgatgatcg tttagtattt
     3361 atcttaaata aattattatt tgagcaagtt ccagttcttt ttgatgattt agctgatgaa
     3421 ctttacgtta gccgttcaac attatctcat gatttcagaa agatacgagt gatgttatca
     3481 gagtataatt tgtccattga gagtagggcg aataaaggag tttatgtctc aggcgaggaa
     3541 cgtgataaac gacgttttat cataaattat ttcctagaga atcaattttt taaaacaata
     3601 cattgctatg taaaatttaa cttttttgat caaactgttc cattagaaga atttgctaga
     3661 attgttttgg atgaatgcca agaggccaac ctaaaactat ctgattttgt actacagaac
     3721 ttagtagttc acatagcatt gtctgtgatt cgtttaaaat ccggatttga aataaaaaat
     3781 atagactgtc agatgactga tgatgcaata gagagaaagg ttgcccaaag aattctttct
     3841 aaagtaagag aagtaacaaa tcaggaattt ccagttcagg aaatagacta cattactttg
     3901 catttgttag ctaagagtca acaatgtcaa aaaaatcaga agaatatttc tgaagaagtt
     3961 ttaaaaaaat ctttatttaa aacatttcag aatttaggat tagatgatat gtataacttt
     4021 tcttcagatt tccaactaat tgaaggattg ataactcatc taatgacact acaagtacgt
     4081 ttagaaagcc ggattacctt aaataaccct ttggtagatg aaattaaaca gaattatagt
     4141 gatatattct ttatgactag agaaattctt gcaaatatgg acaagttctt ggagtggaca
     4201 atatcagatg atgaagtagc atatgtaagt cttcactttt tagctgctat ggaacgtagc
     4261 aaagagagta ctaagtttaa tattcttgct atttgtgcaa caggatttgg tgcagcccaa
     4321 atgttaagaa atcgtttgga aacggagttt gggaagcgag tagaagttgt tgatgtaata
     4381 ggctattatg aattgaatca agaaaaactt aaaggaatag attttatagt gtcagctgtt
     4441 gatttatcaa atctatattt tcaaatccca gtttttaaag ttagtgtgtt tcttaagagt
     4501 gatgagatgg aaatgattag aaaagctatg gatcagatgc aagtttctag ttatgtacaa
     4561 tcatcaaaga ttaacaaatt tgaaaacaac ggctttagac agtattttag taaagaaaac
     4621 tttttaatat gtactgaatc agacaaggta aatttacttg aaaagatggt tgagagttta
     4681 tctgttggtg aatcaaatga gtttgaacaa tctttacttt atggaattaa acagcgcgaa
     4741 gaattaagtt cagttgtttt ttctgaaaaa attgcagttc cgcatcctat tcagcccttt
     4801 ggtacagagg gaaaggtttc ggttgcaatt tgtaaagatt cgttactctg ggataatcaa
     4861 agttcacatg tccagctagt atttcttcta tctccatcaa tatatgggaa cgaaggtttg
     4921 gcaactgtga ctaaaaagat agtctctctg acagagaatg atgaattgca aaatcagcta
     4981 atatcttgca ataactttga agattttatt aacatatttg agaagataaa ataggaggtt
     5041 catatgaatc aagaggaact gcaggttgca gcatttgaaa ttatcctgca ttcgggaaat
     5101 gcaaggtcag aaatacatga agcatttgca aaaatgagag aaggtagttt tgatgatgca
     5161 gaaagtaaat taaatcaatc aaatgagata attcttgaag cgcatcatgc acaaaccaaa
     5221 ctcttgcaag aatacgcaag tggagtggaa attaaaattg aaattatcat ggtacatgct
     5281 caagatcatt taatgaccac tatgacatta ttagaagtag caaaggaaat gttagctctt
     5341 tataagaaag ttaactaaat atgtgttgtt atataaggag gaaatgatat ggataaaaaa
     5401 gaacgacaaa agattgaaca acaacgtcga gagatggctc taactaatac tttttttaat
     5461 cgatatcttc ttctacgtta ttcaatagca ctcttctttt ttgggaatat ttattggctt
     5521 ttgaatcagt ttattaatcc ctcgcctatt attattttcc ccattatgct catagtattt
     5581 tctattttag caactgttga acaatttaaa ctctatggaa ataggaaaga aaagttggga
     5641 ataacactaa tgtttgttag aatacaaatg cttatttcaa taggattact tgttttaact
     5701 tggacaagtt ggtttaagaa tctttttccg atttttgaaa ataaccaagt agcacgttta
     5761 tttgtttttg tagttcttct attaggttta gttctgagtt tgttagacat tagaagaatt
     5821 aaaaaaattt ataaacgaac agataaggct tatcaacaat ttgtccaatt ggaaaagaac
     5881 tcacttagtt tataatcctg atctagtata atttgtattt gaaactagtc tttagaaagt
     5941 aaaaattatt atgttttatt aaggaggtct atttatggat caacaaaacg ggttgtttgg
     6001 ttttcttgaa aaccatgtta tgggaccaat gggcaaactt gctcagttta aagtagtgcg
     6061 tgctatcacg gctgcaggta tggctgctgt accatttact attgtaggat caatgttttt
     6121 ggtattcagt attttgccac aagctttctc attttggcca attgtggcag atattttctc
     6181 tgcttcattt gataaattca catcacttta catggttgca aactatgcga ctatgggttc
     6241 tctatctctt tatttcgttc tatcacttgc atatgaattg acaaaaattt atgcagagga
     6301 agaagaactc aatatgaatc ctcttaatgg tgccttgctt gccttgatgg cttttgtcat
     6361 gacagtaccg caaatcattt ttgatggtgg aatgatgaag actgtgacaa gtctaaaaga
     6421 aggtgcagta attgcagatg gatgggcaat gggaaatgga gtcgcacgtt ttgggacaac
     6481 agggattttt accgcaatca ttatggcaat tgtgactgtt attatttatc gtatgtgtgt
     6541 taaacataat tgggttatta aaatgcctga agctgttcca gaaggagttt ctcgtggatt
     6601 taccgctttg gttccgggat ttgttgttgc atttgttgtt atctttatca acggtcttct
     6661 tgtagcaatg ggaacagatg tttttaaagt cattgcaatt ccatttggtt ttgtatccaa
     6721 tctgactaat tcgtggattg gtttaatgat tatttattta ctgactcaac tactttggat
     6781 tgtaggtatc cacggtgcga acattgtttt tgcatttgtt agtccaattg ctcttgctaa
     6841 catggctgaa aatgctgctg gcgggcactt cgctgttgca ggtgaatttt ctaatatgtt
     6901 tgtaattgca ggtggttctg gtgcaacttt aggactatgt ttatatattg cttttgcctc
     6961 taaatctgaa cagcttaaag caataggacg agcatctgta gttccagcct tatttaatat
     7021 taatgaacca ttaatttttg gattacctat tatctataat ccagccttgg ctataccatt
     7081 tattttagca ccaatggtta ctgctactat ttattacgta gcgaattctc taaactttat
     7141 taagccaatt atcgcacagg ttccatggcc aactccagta gggattggag ctttcttagg
     7201 gacagcagat cttcgagctg tattagttgc tctagtatgt gcatttgcag cattcctagt
     7261 ctatcttcca ttcatccgtg tatatgatca aaaattggtg aaagaagagc aaggtatcta
     7321 ataagtaaaa aagtatactc gatgatagaa tccatatagt ttaaataatg agcgttaaca
     7381 ttagcagtga agaggtcttt ttaagatatt cttctctgct ttttcatatt ttttcgctat
     7441 gtagggtatg aagcaaaata gaaagtagtt cgaatagttg ataaacaggg aactgctgtt
     7501 attttaaaaa aacaataaag taaagtatgt tatcgtagaa tacgatacaa tagtaaaaaa
     7561 gcaaaaagaa tgcgttttat atttgggttt gaggcttata aaataggata agcatgctga
     7621 aaacttagat atgacaaaca aaataaaatt tttaaaagct acatagaaac atggtataat
     7681 gtatctaaag gaggtagcat atgtccttag atatagataa agaaaagatg acaatcatgg
     7741 gaatagcttt tgaaaaccga tccgttttta agagtgtttg gtatgcttta agtacaaata
     7801 tgattgaagg atggcgacct acggttagtg atgttgaaaa attacgagat gaagctcttg
     7861 ctctggggat gacttaatga agcgcaactg ttatgaatct tatgactatg ttgatccgga
     7921 taatttatat accgatccgg gttcttcagt tctaagaaat aagcaggaag gaaaaaagca
     7981 cgtgagcttg aatattgtat gattgctagt aagagtttga aattatttat caatcctatc
     8041 ttagttaata gtttaaaagt agtttgtttc acaactgcat aagcttagaa aagttgaaaa
     8101 gtgataactc tttaataaac tcttggtttg ttaaaagata ttttgtccac tacatttttt
     8161 caattgacta ttatttgtca tagatataac agatagaaca ttgcattcag aataatgaaa
     8221 aacgcatcaa aaatggtgcg ttctgttttt atgctaccat aaaaggaggg aaacaaattg
     8281 aaaattttta agggagagtt ttatcgcatc tctgtattaa cagacaagct agtaaggtta
     8341 gaatactcta aaactggcag ttttgaggat agaactacac aacttatcta taatagagat
     8401 tttggccaag tttcgttaga ttatatcgag acatcaaacg tactagatat tatgacggac
     8461 tattttcatc tgcactttaa taaaggagaa tttaacgccg aaaatttatt tatagaatta
     8521 aaaggaaatt ttgccgtata tggtagtcgc tggtattttg gtgaatcgat tgaaacgtta
     8581 aaaggaacag ctcggactct ggataaggca gatggagcaa tcccattaga agatggaatt
     8641 attagtcgaa atggtatagc cttattggat gattctcaag gatttatttg ggatgaacag
     8701 tctggttata ttgagagaga aaatcaaatt gacctctatt tctttgccta tgggcatgat
     8761 tatagaggag caatcagaga cttttaccat ttgactggtt caacaccctt gttaccaaga
     8821 tatgctttag ggaattggtg gagtagatat tggccttata cgtcggatga atacttggat
     8881 ttaatagaca gatttgaaac agagaaaatt ccattatcta tcggtgtgtt agatatggat
     8941 tggcatataa ctgacattcc agctcgtttt ggaagtggct ggacaggata tagttggaat
     9001 aaaaacttaa tacctaatcc agaacagtta ttgcaacaac ttcatgatag aaagttaaaa
     9061 ctctctttaa atgtccatcc tgctgatggt atacgggctt atgaagaagc ttatcctcaa
     9121 gtcgccaaac gattagggtt aaatgtagaa ctagaagaac ctgccatttt tgattttttt
     9181 aatccctctt ttagggaagc ctactttaaa gatgttcatt atgagctaga aaagcaggga
     9241 gtagattttt ggtggattga ctggcaacaa gggactcaag gcatattgga tccactatgg
     9301 cttttaaacc attatcatta tcaggatagt tgtaaaaatg cagaaggtgg tttgatttta
     9361 tcaagatatg caggtcctgg tagccaccgc taccctgttg gtttttcagg ggacactatt
     9421 attagttgga attccttaag atttcaacct tattttacag cgacagcatc taatatcggt
     9481 tatagttggt ggagccatga tatcggtggg cacatgctgg gagattatga cgaagagctg
     9541 caaactagat ggctacagtt tggtgttttt agtccgatca ctcgattaca tagttctaga
     9601 agtcctttta atagtaaaga accttggttt ttttcagaaa caacatctaa gattatgaag
     9661 aaataccttc gtttgaggca tcagatgatt ccatatctat acactatgaa tgtaaagaca
     9721 cacgaggaag gtgccccatt aatcagccca atgtattatt tctacccaga gaatgatgag
     9781 agctataatg ttccaaacca atactttttt ggaacagaac taatggtggc tcccattgta
     9841 gaaaagatgg acttggcatt ccaatctgca aaagtggatg tatggttccc tgaaggtgaa
     9901 tggtatgact tcttttcaga gaaaaaatat acaggtggtg tgaagttgag tgtttataga
     9961 gacatttcga ctatacctgt gtttgcaaaa agtggtgcga tcattccctt ggttggttct
    10021 gagatagata tgggtgttga tttacctgaa gttgtagatt ggtatgtatt cccaggcaaa
    10081 caacattctt ttgaaatgct tgaagatcaa aatggtcaaa gatataaaac aagattatca
    10141 atcgattggg aaatggggat ggtagagtta acattacaag gagattctag tatcgttcca
    10201 agcaatagaa ggcatagaat tcattttaaa ggaacgaatg tgtctataat tgaattacca
    10261 aataagaatg atacagctag atttgaatgt aaagataata aaacaatatc tttaaatgat
    10321 gaagttttta gactactaaa gacagcttct cttccatatg aattaaaaga tagattgtta
    10381 aatcaattca tcaatgcgaa aaactctcat gacttaatga atatcttgca tcatcaggat
    10441 aaggaattga gagggcgttt gttggaaatg atatttacta gccaaaacta attgatataa
    10501 ttagaaagtc atttgtttag tgtatatgaa gattctgtat ggtattcgtt atcactggtc
    10561 acattgaaaa tgtgaaataa gcacctacaa catagacttt ac
//
LOCUS       DAVLHM010000058        10308 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLHM010000058 DAVLHM010000000
VERSION     DAVLHM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.058"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            112..3213
                     /locus_tag="VXE45_001854"
     CDS             112..3213
                     /locus_tag="VXE45_001854"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0789845.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQKSEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            3295..4302
                     /gene="pfkA"
                     /locus_tag="VXE45_001855"
     CDS             3295..4302
                     /gene="pfkA"
                     /locus_tag="VXE45_001855"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0789846.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     L"
     gene            4361..5866
                     /gene="pyk"
                     /locus_tag="VXE45_001856"
     CDS             4361..5866
                     /gene="pyk"
                     /locus_tag="VXE45_001856"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0789847.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6600..6825)
                     /locus_tag="VXE45_001857"
                     /pseudo
     CDS             complement(6600..6825)
                     /locus_tag="VXE45_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7673..8545
                     /locus_tag="VXE45_001858"
     CDS             7673..8545
                     /locus_tag="VXE45_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0789848.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            8558..8722
                     /locus_tag="VXE45_001859"
     CDS             8558..8722
                     /locus_tag="VXE45_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789849.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(8691..9035)
                     /locus_tag="VXE45_001860"
                     /pseudo
     CDS             complement(8691..9035)
                     /locus_tag="VXE45_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9178..9489
                     /locus_tag="VXE45_001861"
     CDS             9178..9489
                     /locus_tag="VXE45_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789850.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9493..10209
                     /locus_tag="VXE45_001862"
     CDS             9493..10209
                     /locus_tag="VXE45_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0789851.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT         3191 a         1781 c         2189 g         3147 t
ORIGIN      
        1 atacaaatga atagaaaata aattagtaag ctgatgaaat ttttctcaag agaagccatt
       61 tataggtgaa aatggtataa tatagtgaga aggatagagg agaagtgtaa attgatcgca
      121 caactagata caaaaacagt ctatagtttt atggaaagcg tcatttcgat cgaaaagtat
      181 gtgagagcag ctaaagaata cggctacact catttggcta tgatggatat tgacaatctt
      241 tatggcgctt tcgactttct agagattaca aaaaaatacg gcattcatcc tttgctaggg
      301 cttgaaatga cagtgtttgt agatgatcag gaagtgaatt tgcgcttttt agctctatct
      361 agtgtgggct atcagcagtt gatgaagctt tcgacagcca agatgcaggg ggagaaaact
      421 tggtcagtcc tgtcccagta cctggaggat atcgcggtca ttgtgcctta ttttgataga
      481 gttgagtcgt tagaactagg ctgtgattac tatatagggg tttatccaga aacactagca
      541 agcgaatttc atcatcctat cttacctctt tatcgggtca acgcttttga aagcagggat
      601 agagaagttc ttcaagtttt aacagcgatt aaagaaaatc taccgctcag agaagttccc
      661 ttgcgttcga gacaagatgt ctttatatca gcaagttctt tagagaaact attccaagag
      721 tgttttccgc aagctttgga caatttagaa aagcttattt caggcatttc ttacgacttg
      781 gatactagtc tgaaactgcc tcgttttaat ccagctagac cagcagtaga ggagttgaga
      841 gagcgtgctg aactggggct tgttcagaag gggttgacta gtaaagaata tcaagataga
      901 ctagaccaag aattgtctgt tattcatgat atgggctttg atgattattt cttggttgtt
      961 tgggatttgt tgcgttttgg acgatcgaat ggctattata tgggaatggg aaggggttct
     1021 gcagtaggca gtttggtttc ttatgcctta gacatcacgg ggattgaccc agtagagaaa
     1081 aatctgattt ttgaacgctt tcttaatcgt gaacgctata ccatgcctga tattgatatt
     1141 gatatcccag atatttatcg tccagatttt atcagatatg ttggtaataa atatggtagt
     1201 aaacatgcgg cacaaatcgt tactttttca acctttggag ccaagcaagc tcttcgagat
     1261 gtcttgaaac gctttggtgt gccagagtat gaattatctg caattactaa gaaaatcagt
     1321 tttcgtgaca atcttaagtc ggcctatgag ggcaatctcc agtttcgtca gcaaatcaat
     1381 agtaagttag aataccaaaa agcttttgag attgcttgca agatagaggg ctatccaaga
     1441 caaacctctg tccatgcggc tggtgttgta attagtgacc aagatttaac caactatatt
     1501 cctctaaagt atggtgatga aattccactg actcagtatg atgctcatgg agttgaggct
     1561 agcggacttt tgaagatgga ctttctggga ctacgaaatt tgacctttgt ccagaagatg
     1621 caagagttgc ttgctgaaat agaaggtatt caccttaaaa ttgaagaaat agatttggaa
     1681 gacaaagaaa cgttagcttt atttgcctct ggaaatacaa aaggtatctt tcaatttgag
     1741 caaccaggtg ccattcgtct gcttaagcgt gtgcaaccag tctgttttga agatgtcgtc
     1801 gcgactactt ctctaaatcg accgggtgct agtgactata tcaataattt tgtggcaaga
     1861 aagcatgggc aggaagaagt gactgttctg gatccagtac tggaggatat tttggctcca
     1921 acctacggca taatgctcta tcaggagcag gttatgcagg ttgcccagcg atttgccgga
     1981 tttagtcttg ggaaagccga tattttgcgt cgggctatgg ggaaaaagga tgcctctgcc
     2041 atgcatgaga tgagggcttc ctttattcaa ggttcattag aagctggtca tactgtggaa
     2101 aaagcagagc aggtctttga tgttatggag aagtttgcag gttatggttt taacaggtca
     2161 cacgcctatg cctactcagc cttggccttc cagttggctt attttaaaac acattatcca
     2221 gccatttttt atcaggtcat gttaaattct tccaacagtg attacttaat agatgcactt
     2281 gaagcaggtt ttgaagtagc ctctctatcc atcaacacca ttccctatca cgataaaatt
     2341 gccaacaagg ccatctatct aggtttgaaa tccattaaag gagtcagtaa tgatttagct
     2401 ctctggatta ttgaaaatag accttattct aacattgaag attttatagc taaattacct
     2461 gagaattatc tgaaacttcc tctgctagaa cctttggtaa aagttggtct tttcgattca
     2521 tttgaaaaaa atcgtcaaaa agtatttaat aatttagcta atctatttga atttgtgaaa
     2581 gagttgggaa gtttgtttgg agatgctatt tatagttggc agaaatcgga agattggacg
     2641 gaacaagaaa aattttatat ggaacaagag cttttaggga taggtgtcag caaacatcca
     2701 ctacaagcta ttgcaagtaa ggctatttac ccgattaccc caatcggaaa tttgtcagaa
     2761 aatagctatg ctattatttt ggttgaagtt cagaaaataa aagtgattcg taccaaaaag
     2821 ggtgaaaata tggctttctt acaggtggat gacagtaaga aaaaattgga tgttacactc
     2881 ttctcagatt tatatcgaca ggttggtcag gaagtaagag aaggagcatt ctactatatc
     2941 aaagggaaag tccaatcacg tgacggtcgt ctgcaaatga ttgcacaaga aataagagaa
     3001 gcagttgctg aacgcttttg gattcaggtt aaaaatcatg actcggatca agagatgtca
     3061 cgtattttag accagtataa aggcccaatc ccagtcatca tccggtatga agaggaacag
     3121 aaaaccatcg tttctcccca tcattttgta gctaaatctg atgaattaga ggcgaaattg
     3181 aatggaatag ttatgaaaac gatttatcgc taaaattacg gaaaatagaa gaattttcaa
     3241 cgtaaatgtg gtataatcag taagaatgtt aaaagaaaaa ggagcataac caatatgaaa
     3301 cgtattgctg ttttgactag tggtggagac gcccctggta tgaacgctgc catccgtgca
     3361 gttgttcgtc aagcaatttc agaaggaatg gaagtgtttg gtatctatga cggatatgct
     3421 ggtatggttg ccggtgaaat tcatccccta gatgcagctt cagtagggga catcatttct
     3481 cgtggtggta ctttccttca ctcagctcgt tacccagagt tcgctcaact tgaagggcaa
     3541 cttaaaggga ttgagcaatt gaaaaaacac ggaattgaag gtgtagttgt tatcggtggt
     3601 gacggatctt accacggcgc tatgcgtttg actgaacatg gcttcccagc tattggtctt
     3661 ccaggtacaa tcgataacga tatcgttggt actgacttta caatcggttt tgacacagcg
     3721 gttactactg ccatggacgc tatcgataag attcgtgata catcatcaag tcaccgtcgt
     3781 acttttgtaa tcgaagttat gggacgtaac gctggtgata tcgctctttg ggctggtatt
     3841 gcaactggtg ctgatgaaat catcatccct gaagcaggct tcaagatgga agatatcgta
     3901 gcaagcatca aagctggtta tgaatgtggt aaaaaacaca atatcatcgt cttagctgaa
     3961 ggtgtgatgt cagcggctga atttggtcaa aaacttaaag aagctggaga tacaagcgac
     4021 cttcgtgtaa cagaacttgg acatattcaa cgtggtggtt ctccaactgc gcgtgaccgt
     4081 gttttggcgt cacgtatggg tgcacatgct gttaaacttc ttaaagaagg tatcggtggt
     4141 gttgcggttg gtattcgtaa cgaaaaaatg gttgaaaatc caattcttgg tactgcagaa
     4201 gaaggggcat tgtttagcct tactgcagaa ggtaagattg tggttaacaa cccacacaaa
     4261 gccgatattg agctatctag cttgaataag agcttgttat aatttacaat ttagttaata
     4321 agaccaaaaa ggtcatatat ataaaggagt cacaaaaatc atgaacaaac gtgtaaaaat
     4381 cgttgcaact ttgggtcctg cggtagaaat ccgtggtggt aaaaaattcg gtgaggacgg
     4441 atactggggt gaaaaacttg atgttgaagc ttcagctaaa aacattgcta aattgattga
     4501 agctggtgct aacacattcc gattcaactt ctcacacggc gaccaccaag aacaaggtga
     4561 gcgtatggca actgttaaac ttgcggaaaa aattgcaggt aaaaaagttg gtttccttct
     4621 tgatacaaaa ggacctgaaa tccgtacaga attgttcgaa ggtgaagcta aagaatattc
     4681 atacaaaact ggtgaaaaaa ttcgtgttgc aactaaacaa ggaatcaaat caactcgtga
     4741 agtgattgcg ttgaacgttg ctggtgctct tgatatctat gatgatgttg aagttggtcg
     4801 tcaagttttg gttgacgatg gtaaacttgg tcttcgtgtg gttgctaaag atgatgcaac
     4861 tcgtgaattt gaagttgaag ttgaaaacga tggtatcatc gctaaacaaa aaggtgtgaa
     4921 catccctaac actaaaattc ctttcccagc tcttgctgaa cgcgataacg acgatatccg
     4981 tttcggtctt gaacaaggta tcaacttcat cgcaatttca ttcgtacgta ctgcaaaaga
     5041 tgtgaacgaa gttcgtgcaa tctgtgaaga aactggaaac ggacatgttc aattgttcgc
     5101 taaaatcgaa aaccaacaag gtatcgataa cttagacgaa atcatcgaag cagctgatgg
     5161 tattatgatt gctcgtggtg atatgggtat cgaagtaccg ttcgaaatgg ttccagttta
     5221 tcaaaaaatg attatcaaga aagtcaatgc tgcaggtaaa gttgttatca ctgcaacaaa
     5281 catgcttgaa acaatgactg aaaaaccacg tgcaactcgt tcagaagtat cagacgtatt
     5341 caacgctgtt atcgacggaa ctgacgctac aatgctgtca ggcgagtctg caaacggtaa
     5401 atacccactc gagtcagtaa ctacaatggc tacaatcgac aagaacgctc aagctcttct
     5461 taatgaatac ggacgtcttg attcagattc atttgagcgt aactctaaga cagaagtaat
     5521 ggcttctgct gttaaagatg ctactagctc aatggatatc aaattggttg taactcttac
     5581 taagacaggt catactgcac gtttgatttc taaataccgt ccaaatgctg acatcttagc
     5641 attgacattt gacgaattga cagaacgtgg cttgatgttg aactggggtg ttatcccaat
     5701 gttgacagat gctccatctt caactgacga tatgttcgaa atcgctgaac gtaaagcggt
     5761 agaagcaggt ctcgttgagt caggcgatga tatcgttatc gttgctggtg tgccagtagg
     5821 agaagctgtt cgcacaaaca caatgcgtat ccgcacagta cgttaagaaa aatataaaaa
     5881 cctatcatat ccagctttct agcctgtatg atgggctctt tttttgtcca gggggcaaaa
     5941 agggggcaaa actttcataa tggattgata ctcttcgaaa atctcttcaa accacgtcag
     6001 cgtcgcctta ccgtatatat gttactgact tcgtcagttc tatctacaac ctcaaagcag
     6061 tgctttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtatgaa
     6121 ataagatatg cacaaattga ttaggaaatt caaatgaatt tctacaaatg ttttagcaat
     6181 cgcaatctac ttgtctagat tcgatctgat atattttcga tttaatgata tggtatttaa
     6241 aacctccaaa gtagcttgct ccattctttt acttacgtga gtgtagatgt tatttactgt
     6301 tttagcgttt ttgtgttcta ctctaaccat tatagcattc ttctcagcta gtgtactaag
     6361 gagtgtgtgc ctgaaaatat gggaactaag ggctggttta tcggtttctc tagtttagta
     6421 tttgcctttt gcaaagtgat cttaaatgcc tttctctaaa tttacatatc actattgttt
     6481 aacaaaatct aatctacttt aggtcactta ttcttttttt gaaatgtaga atgaactttt
     6541 tcaaagtttt tcgaatcttt taaaatctgt ttgttttata tcgccattct cccccttttt
     6601 taattctccc tatatagcct gacaactttc ccgatggtac gaatatggtt gctttcgtct
     6661 aggtggatgt cggagtattc gggattgagt ttttttgagg tagccttggc ggagtttctt
     6721 gacatagtta gtgccgtcta cttggaagat gccgatggta ttatagtcaa tctgtggggt
     6781 attcttgata aataggtagt cgctgtttct tatctttggc tccatggact tgctgacgac
     6841 ataagcgatt gggtcgtagt cgtctgggat aatggaaact ccataactaa atcgtcgtcc
     6901 tgcatcaagc ggctacctgc agagataaac tacctaacac gagagtaagt agtctgtctg
     6961 tagtcgtcca gtctgatgat ttttacgata cttcgttttt ctgatcatac agttgcctct
     7021 cggcataggt cagaacttta ccttgtctgg gtggtgcccg ttggtcgtag atagattgga
     7081 tatcgctagg agaatccttt tgaactggag gaaagagggc atcaatcaag ctactgaata
     7141 ctttaactaa gtcaaatata gtatttttct tagtagacct aacccttttt tcataatttc
     7201 taatggtgtt tttacttata cctatcttag tacccaattc ttattgagtc caaccattac
     7261 tagtctatat tgttttatag ttgattgagt ttggaatagt acgctgtagc tgctaaaaca
     7321 tttctaggaa ttaatttgcc tttcctaata gagttgttca tatcttattt caatctacta
     7381 tatttttcac ctctaacaat cgcaatctct tctttatcca tgaacgaaaa cgctttctat
     7441 ctttgtaagt aaagcatcac acgaaatcca cgaaaatgaa aacctttgtt gtgttttcgt
     7501 aaaaaatttg ttgacagagc acgaaacgcc tactataatt aaatcaagtt taaggaaata
     7561 acaaaaaaac aaatcggagg gaaagacgat gaacacatta aatgagaaag taatcaatat
     7621 ctgtaaagca gtagttaaag aaactttaat ccaagacatt taggagaaag aaatgaagaa
     7681 atcaagaaaa ttagccacat taggaatctg ttcagccttg tttttaggct tggctgcttg
     7741 tcaacaacaa catgctactt ctgaggggac gaatcaaagg caaagcagtt cagcgaaagt
     7801 tccatggaaa gcttcataca ccaacctaaa caaccaggta agtacagaag aggtcaaatc
     7861 tctcttatca gctcacttgg atccaaatag tgttgatgca ttttttaatc tcgttaatga
     7921 ctataatacc attgtcggct caactggctt atcaggagat ttcacttcct ttactcacac
     7981 cgaatacgat gttgagaaaa tcagtcatct ctggaatcaa aagaagggcg atttcgttgg
     8041 gaccaactgc cgtatcaata gttattgtct tttgaaaaat tcagtcacca ttccaaagct
     8101 tgaaaagaat gaccagttgc ttttcctaga taatgatgcg attgataaag gaaaggtctt
     8161 tgattcacaa gataaggaag agtttgatat tctattttcg agagttccaa ctgaggcaac
     8221 tacagatgtc aaggttcacg ctgaaaagat ggaaacattc ttctcacaat ttcaattcaa
     8281 tgaaaaagct cgaatgctgt ctgtagtctt gcacgacaat ctggatggcg agtatctgtt
     8341 tgtaggtcac gttggggtct tagtacctgc tgatgacggt ttcttatttg tagagaaatt
     8401 gactttcgaa gaaccctacc aagcgattaa atttgctagt aaggaagatt gctacaagta
     8461 tttgggcacc aagtatgcgg attatacagg cgagggactg gctaagcctt ttatcatgga
     8521 taatgataag tgggttaaac tttaatagtg ttatgatatg acagtaatct taggattttt
     8581 atttctattt ttgatgactt ggtgggttat ttcaatcgtt aatagccaga aaccactcaa
     8641 aaatgaaaca tttattggct atgtccaaag atacgatatt gatgggaatg gctatcaatc
     8701 attaccgtgt cctcagaact gagaggagtt cttgaaatcg taacaccact ttgaacaaga
     8761 gttacttcaa cccattggct ccgccggagt aagttgcttt cgtgaacacc aaaatcagcc
     8821 gcaatttctt cataagtgcg gtattctcac acatattgaa gagtggccat aagaaggtct
     8881 tctaggctta atttaggttt tcgtccacct tttgcgtgtt taagttgata agctgttttt
     8941 aatacagcta acatctcttc aaaagtggta cgctgaacac caacaagacg cttaaatcgt
     9001 gcatcagtta gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt
     9061 cgcaggaagt ctaatgctaa aatcttatca gtgagaagat ttcttaaagt ttattctttg
     9121 tagtttcatc tgtattagta cataatttaa cttagagaaa ataggaggac taatcgaatg
     9181 gaattaaaag attttacaga aaaagaacag gaaatgatta agaaaaggct tacaatgtct
     9241 aatattagtg acaaagaaac tactgagaag attctggcgc tagtaccaca agacttgatt
     9301 aagcgaatcc cgttttttgt cagaaaacat gctacaacac gtacgattaa acgcatttca
     9361 attgaatacc ctgaactcta cgctgtagct caaacaagtg gtgagattcc agaaaaagaa
     9421 cgcgaagaat tgcgtcagat tatcacaact atctttgaac aaaagatgaa taagcatagt
     9481 attaagtaga gaatgaaaaa atattttatt agcggtttgg gaagcaatgc ctatcatagc
     9541 aaggattttt ttcaagaact agattcgcag gtctattttc taaatccata tgaaaagcat
     9601 cttcgagatg aaacagaatt gaaatcatgg tttaaaaatg agattgtaga ggaagaatct
     9661 atctgtctga taggccattc tcttggagga gatttagctc gttatttcgc atcggaattt
     9721 gaagaagtaa agaaactgat tcttttggat ggtggctatc tagatttaga taagatttta
     9781 cctttggata cagagttaga ggaaactaaa aattatatca aatctcaaat tgtttcggac
     9841 ttagctcttc ttatttctaa agagaagtcc gaagcaaagc attggtcaga aaatatggag
     9901 aaagctgtaa gacagtccta tcactggaat gttgagtata atagatatga gttggctata
     9961 aattatgaaa atatagaagc gatactccgc ctacggagaa aaatacaagc ttttaagaga
    10021 gaagtgggag ataccttgtt tattagtcct cgctatccta atggagctac atggagagag
    10081 gaagccctaa aagaattgcc agactatttt aatactattt ttttagaaaa ctttggccat
    10141 gagctttata ctcaagcacc taaagaaatc gctagtctaa tgaatgagtg gctcgcttat
    10201 tttctatgag ctacttgtat tgctggaaat ggtataagat gaaaatctac aggctctata
    10261 atatttgtag tgggtaaatc cactatagat attatggagc ctattttt
//
LOCUS       DAVLHM010000059        10228 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLHM010000059 DAVLHM010000000
VERSION     DAVLHM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10228
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.059"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(71..307)
                     /locus_tag="VXE45_001863"
     CDS             complement(71..307)
                     /locus_tag="VXE45_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0789852.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(375..1295)
                     /locus_tag="VXE45_001864"
     CDS             complement(375..1295)
                     /locus_tag="VXE45_001864"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0789853.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1493..1897
                     /locus_tag="VXE45_001865"
     CDS             1493..1897
                     /locus_tag="VXE45_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789854.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            2113..2694
                     /locus_tag="VXE45_001866"
     CDS             2113..2694
                     /locus_tag="VXE45_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0789855.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQKKQ
                     GAPSAKSKMEGVFGNCEILKKDKGYYILRSVKE"
     gene            2691..3968
                     /locus_tag="VXE45_001867"
     CDS             2691..3968
                     /locus_tag="VXE45_001867"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0789856.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3986..4648
                     /gene="deoC"
                     /locus_tag="VXE45_001868"
     CDS             3986..4648
                     /gene="deoC"
                     /locus_tag="VXE45_001868"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0789857.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4635..5024
                     /locus_tag="VXE45_001869"
     CDS             4635..5024
                     /locus_tag="VXE45_001869"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0789858.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5114..6166
                     /locus_tag="VXE45_001870"
     CDS             5114..6166
                     /locus_tag="VXE45_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0789859.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6310..7845
                     /locus_tag="VXE45_001871"
     CDS             6310..7845
                     /locus_tag="VXE45_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789860.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7838..8896
                     /locus_tag="VXE45_001872"
     CDS             7838..8896
                     /locus_tag="VXE45_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789861.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8899..9855
                     /locus_tag="VXE45_001873"
     CDS             8899..9855
                     /locus_tag="VXE45_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789862.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9940..10228
                     /locus_tag="VXE45_001874"
                     /pseudo
     CDS             9940..10228
                     /locus_tag="VXE45_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2933 a         1797 c         2346 g         3152 t
ORIGIN      
        1 gataattgcg attttcattt tctacctttt cctatttgga gacaaaaaaa cagcctctat
       61 ggactgtttc ttatttagca agtttagctg aaagacgagc tttatcgcgg cttgctttgt
      121 ttttgtgaat caaaccttta gtttctgctt tatcgatagc tgagctagca gcacggaaaa
      181 gttcttcaga tgggtttgct tcgaaagctt ttatagcagt acgcatagct gatttttgag
      241 ctgagttctt ttcgttttgt ttaacgttca attcagcgcg tttgatagct gatttaatgt
      301 ttgccaatgt tcttacctcc atatttacta actataccat tatatatgaa aacttacgtt
      361 ttgacaaggg aaaattattt ttttaagtaa atttcatcga tttcatggtt cttgctttta
      421 tgaagaatca cttctgcacg atttctggtt ggttcaatat aattttgtag atttgtgaga
      481 ttgatactgg tccagacctg atgggcaaag gcttccactt ccccaatcgg catctgagta
      541 aaacgataat agtagctatc agggtcgttt tgggctagac tcagcatttt caagaaacgg
      601 tccagatacc aactttcaat atcatccact ccagcatcta catagatgga aaagtcaaag
      661 aagtcagtga tatagagacg atcgttttgt ggattttgaa agacattgat tccctcaaca
      721 attacaaaat cagcagcttt gacactttgt ttctcttcgg gtacgatgtc gtaaacttca
      781 tgagaataga caggaatatc tacatcttgt ccatttttga tgcggtccaa gaagttgaga
      841 agagcttcca tatcatagct ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc
      901 aaggtttgat tgggatagag aaaaccatca gttgtaacca actcaaccgt agcatctgta
      961 aacgtacggg acagtaggat ttgaagtagg cgactggttg tggattttcc aacggcaaca
     1021 ctcccagaaa ccccaataat aaaaggttga gatttacttt cacgttggag gaaaattcct
     1081 tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg agccaagggg
     1141 agatagatat ctgtaacgtc ttggagactg atttggtcat taaaactctt gatagattcc
     1201 aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca agtctggcgg
     1261 ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga tattttgtct
     1321 atcataccat aaaaatctaa aaaaataaag cggtttcttg aatgtggtaa gtcaatggta
     1381 tatagtataa gtgatcaatt tattgatgaa ataggagata gattctactg atttataagt
     1441 ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat
     1501 cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa
     1561 aggagccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt
     1621 gatggaacat gctattgtaa cagctgtctt tatctattcg tttttaattg ctttcttact
     1681 aaaaaaacga tgggcgaaat ggattgctgc tggtagttat tgctttttag tcctatggat
     1741 tgcgacagag ggttatttct tccgcatgtc actagaagat ttgatacgac tttggacaag
     1801 tttggaaatc ctgacacaaa cgtatcagtt gggcttttat ctaaacattt tgttgggaat
     1861 tttgttgata ataaagtatt ttaaggttaa gcaatagaaa taataatctg cctgattata
     1921 gatgataaac tttttgtttt tatctggact gtgatattta tagttctaaa tggtttatta
     1981 tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg actcgctttc ttcggtcttt
     2041 ttcgttttat tatcaatttg taaacgattt acaatttgag tcaaattatg gtaaaatagt
     2101 gtcatgagta aaatgtatta tgcagaaaat cctgacgctg ctcacgacat tcatgagttg
     2161 agagtagagt tgttgggaca aaaaatgacc tttttaacgg atgcgggtgt ttttagcaag
     2221 aaaatagttg actttggaag tcaactattg ctcaagtgtc ttgaggtcaa ccaaggagaa
     2281 actgtccttg atgtaggctg tggttacgga cctttgggtt tgtccttagc taaggcttat
     2341 ggagttcagg ctactatggt tgatatcaac actcgtgcct tagatttagc tcggagaaat
     2401 gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca acatctatga acaagttgaa
     2461 ggacattttg atcatgtcat ttccaatcct cctatccgtg cgggcaagca agtcgttcat
     2521 gaaatcattg agaaaagtaa agatttcttg gaaactagtg gggatttgac aatcgtcatc
     2581 cagaaaaaac aaggggctcc aagtgctaag tccaagatgg agggtgtgtt tggtaattgt
     2641 gaaatcctta aaaaagacaa gggatactat atccttagaa gtgtgaaaga atgagagcag
     2701 ttgatttaat acaaaaaaaa cgagacggtc aagaactgac ttcaagtgaa attgaatggc
     2761 tggtagaagg ctatgtgtca ggaactgttc ctgattatca gatgtctgcc tttgctatgg
     2821 ctgtttattt taaaggaatg acgactcgag aaatctctga tttaacgatg aatatggtta
     2881 agactgggca agagtttgac ctgtcagcca ttgatggtgt gaaagttgac aagcattcta
     2941 ctggtggtgt cggcgataag gtaaccttga ttttagttcc tcttgttgct agcttcggtg
     3001 tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac aggcggaaca attgataaat
     3061 tggagtccat taagggctat caagtagaac gtagtcaaga ggattttatt cgtcaggttc
     3121 aggatattgg agtatctgtc attgggcaat cagaccagct ggtcaaagca gataagcttc
     3181 tctatgccct tcgtgatgtg accgcaactg tcgacacgat tcctttgatt gcgagttcgg
     3241 tgatgagcaa gaaaattgcg gcaggggcgg atgctatttt gctagacgtg actgtcggtg
     3301 agggtgcctt catgaagacg gttgatgagg cgcgtgagtt ggctcaaact atggtagatc
     3361 ttggtaaggt tgttggacgg aagacagtag cagtgattac ggatatgagc cagcctttgg
     3421 gacgagcgat tggaaatcgt ctggaaatcc ttgaagcatt ggagattttg caaggtcaag
     3481 gacgtcagga tattacccac tttatttgtg aattggctca aattatgctt ggtttggcaa
     3541 atgttaacaa aactgttgaa gaagttcgcc aacatcttga gaatggtcaa gcactggcta
     3601 agtttgagga aatggtgcaa gcccaaggtg gagacttgga agacctctat cgtcctgtaa
     3661 atgtagctca tgtggtggaa atccctgctc aggaaacggg tgtcatttca gctcttccag
     3721 ctatggactt tggtctttat gccatgaggc tgggtgctgg tcgtgcagtt aagtctgatg
     3781 ccttggacta tgaaacagga attgtttttg aaaagaagat tggagactcc gttcaaaagg
     3841 gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc acctcaacta gttacagatt
     3901 tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat ccgtgaaatt gtagaaatca
     3961 tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa tatatagatc atacgctttt
     4021 aaaacaagat gcaaagaaaa aacaaattga tagtttgttg tctgaggcta gagagtatga
     4081 ctttgccagt gtttgcgtta atccgacctg ggttgaacat gctaaaaaag gacttgaagg
     4141 cacagatgtt aaggtttgca cagtagtagg tttccctttg ggagcaacaa cttcagccgt
     4201 gaaagcattt gagacaaaag aagctatcca aaatggtgca gatgagattg atatggtgat
     4261 caatgttgga gctctcaaat caggtaattt agccttggtt gagtcagata ttcgcgcagt
     4321 agtggaagca agtggtgata agttagtgaa agtcattatt gaagcttgcc ttctgacaga
     4381 ccaagaaaaa attgttgttt gccaattggc ccaaaaagct ggggctgact ttgttaaaac
     4441 atctactggt ttttcaactg gtggtgctac gatagcagat gttacattaa tgcgtgaaac
     4501 agttggatct gatatgggag tcaaggctgc tggtggagct cgttcttatg cagatgctct
     4561 tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca gctggggtag ctattttaaa
     4621 aggagaattg gcagatggcg actactgagt tgattgaact ggcaattgaa accagcaaac
     4681 atgcatatgt cccctattct cactttccta tcggagcagt tttagtagcc aaagacggaa
     4741 gtgtttacac gggagtgaat atcgaaaatg ctagctatcc tttgaccaat tgcggtgaga
     4801 gaacagctat ttttaaggct atatctgaag gccaaagaga attttcagaa ttgattgtct
     4861 atggtcaaac tgaaaaaccg atctcgccat gtggtgcttg tcgccaagtg atggctgaat
     4921 tttttgaaca agatctaaaa gtgaccttag tcgcaaaaga taaatcgacg gtcgagatga
     4981 cggtcgggga attacttcca tactctttta cagacttaaa ctagtctgag tcgctctctg
     5041 agtggcacgg tccttgtggc caaccaatcc atacttgcaa catcgttgca catcttattt
     5101 aggaggttca gtaatgaaca agaaacaatg gctaggtctt ggcctagttg cagtggcagc
     5161 agttggactt gctgcatgtg gtaaccgctc ttctcgtaac gcagcttcat cttctgatgt
     5221 gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt gatgacaaat cattcaacca
     5281 atcagcttgg gaaggtttgc aggcttgggg taaagaacac aatctttcaa aagataacgg
     5341 tttcacttac ttccaatcaa caagtgaagc tgactacgct aacaacttgc aacaagcggc
     5401 tggaagttac aacctaatct tcggtgttgg ttttgccctt cataatgcag ttaaagatgc
     5461 agcaaaagaa cacactgact tgaactatgt cttgattgat gatgtgatta aagaccaaaa
     5521 gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt taccttgcag gtgtggctgc
     5581 agcaaaaaca actaagacaa aacaagttgg ttttgtaggt ggtatcgaat ctgaagttat
     5641 ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca gtagacccat ctatcaaagt
     5701 ccaagttgac tacgctggtt catttggtga tgcggctaaa ggtaaaacaa ttgcagccgc
     5761 acaatacgca gccggtgcag atattgttta ccaagtagct ggtggtacag gtgcaggtgt
     5821 ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa aatgaaaaag tttgggttat
     5881 cggtgttgat cgtgaccaag aagcagaagg taaatacact tctaaagatg gcaaagaatc
     5941 aaactttgtt cttgtatcta ctttgaaaca agttggtaca actgtaaaag atatttctaa
     6001 caaggcagaa aaaggagaat tccctggcgg tcaagtgatc gtttactcat tgaaggataa
     6061 aggggttgac ttggcagtaa caaacctttc agaagaaggt aaaaaagctg tcgaagatgc
     6121 aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa aaataatgga tggaagtcat
     6181 ttcttaggaa gcggccaagg gccgcttttt taagagttga gacaaagtca ttttgtctca
     6241 gtaaagcttg ctactagaca aactagcaag ttttattgaa ataaaataag actctgaaag
     6301 gaagagcaca tggcacacga aaatgtcatt gagatgcgtg atattaccaa ggtgtttggt
     6361 ggatttgttg ccaacgacaa aatcaacttg cacctacgaa aaggtgaaat tcatgcactt
     6421 ttaggagaaa atggggctgg taagtccacg ctaatgaaca tgttagcagg ccttcttgaa
     6481 ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca atctcgactc cccatctaaa
     6541 gcagctagct tgggaatcgg gatggttcac cagcacttta tgttggttga agccttcaca
     6601 gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa atggtgtgct agatatcgct
     6661 ggagctagca aagaaatcaa ggctctttct gaacgttatg gcttagctgt tgacccttct
     6721 gccaaggtag cagatatctc agttggagcc caacaacgtg tagaaatttt aaaaacactt
     6781 tatcgggggg ctgatatcct tatctttgac gaaccaacgg ctgttttgac tccatcagaa
     6841 attgatgagt tgatggctat tatgaaaaat cttgtcaaag aaggaaaatc aattatcttg
     6901 attacccaca aattggatga aattcgcgca gtttctgacc gtgttacagt tatccgtcgt
     6961 gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca atgctgattt ggcggaaatg
     7021 atggtaggac gttctgtttc ctttaaaaca gagaagcaag cctctaaacc aaaagaagtg
     7081 gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg gtgttccagc tgttaaaaat
     7141 ctgtccttgg atgttcgtgc tggagagatt gttggtattg cggggattga tggaaatggt
     7201 cagtctgaac tgattcaagc cattacaggt cttcgtaagg ttgaatctgg tagcattgag
     7261 ctaaaagggg attcaattgt aggcttgcac ccacgtcaga ttacagaact aagtgttggg
     7321 cacgttccag aagaccgtca ccgtgatggc ttgattttgg aaatgatgat atctgaaaat
     7381 attgcccttc aaacctacta taaagaacca catagtaaaa atggaatttt gaattattca
     7441 aatattactt cttatgctaa aaagctgatg gaagagtttg atgttcgcgc tgccagtgaa
     7501 ttagttcctg cagctgcact ctcaggagga aatcaacaaa aagcaattat tgctcgtgaa
     7561 attgatcgag atcctgatct ccttatcgtt agccagccaa ctcgtgggtt ggatgtcggt
     7621 gccattgagt atatccacaa acgcttgatt gaagagcgtg ataatggcaa ggctgtcctt
     7681 gttgtcagct ttgaattgga tgagatttta aacgtctcag accgtattgc cgttatccac
     7741 gatggtaaga ttcaaggtat tgtatcacca gaaacaacca ataaacaaga acttggtgtc
     7801 ttgatggctg gtggaaactt gggaaaggag aagagtgatg tttaaaaaat tacaacaaat
     7861 ttcggttccc ttgatttctg tatttctagg aattttactc ggagccattg tcatgtggat
     7921 cttcggttat gatgctattt ggggctacga agaattgttc tatacagcct ttggcagtct
     7981 gcgtgggatt ggagaaatct tccgtgctat gggtcctctg gtcttgattg gtcttggttt
     8041 tgcggttgcc agtcgagctg gtttctttaa cgtcggactt cctggtcagg ctttggcagg
     8101 ttggattctc agtggttggt ttgccctgtc gcatccagat atgccccgtc ccttgatgat
     8161 tctagcaacc atcgtgattg ccttgattgc tggtgggatt gtcggagcga ttccaggtat
     8221 tcttagggcc tatctaggga cgtcagaggt tattgtaacc atcatgatga actacattgt
     8281 cttgtatgta gggaatgcct ttatccatgc tttccctaaa gacttcatgc aaagtacaga
     8341 ttcgaccatt cgtgttgggg ctaatgcaac ctatcagaca ccttggttgg ctgagttgac
     8401 tggtaactca cggatgaata ttggtatttt ctttgccatc attgccgttg cagttatttg
     8461 gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt gcagttggtc ttaatccaca
     8521 tgcttcagaa tatgctggta tttctgccaa gcggactatt atcctatcta tgattatttc
     8581 aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg ggaaccttcc agaacgtcta
     8641 tgttcaaggt tcgtcattag ctatcggatt taacggaatg gcggttagtt tgcttgcggc
     8701 caactcacca attggtatac tctttgcagc cttcctattt ggcgttctcc aagttggggc
     8761 tcctggtatg aatgctgcgc aggtaccatc tgagcttgtc agcattgtaa cagcgtctat
     8821 tatcttcttt gtcagtgttc attaccttat cgaacgcttt gttaaaccga aaaaacaagt
     8881 taaaggaggt aagtaaagat gtctattata accttgctcc ccctcttggt gtcttctatg
     8941 ctgatttact cagcacctct catctttaca agtatcggtg gtgttttctc tgaacgtggt
     9001 ggtgtggtaa acgttggcct tgaaggaatt atggttatgg gtgccttttc tggagttgtc
     9061 tttaaccttg aatttgcaga acaatttgga gcagcaactc catggctatc cttgcttgta
     9121 gcaggattgg ttggtagtgt tttctctatc atccacgcag cagcgacggt tcatttccgt
     9181 gcagaccatg ttgtcagcgg tacggtattg aacttgatgg cgcctgcctt ggctgttttc
     9241 ttagttaaag ttctttataa caaaggacaa accgacaacc taagtcaaac ttttggacgc
     9301 tttgatttcc cagtcttggc aaatatccca gtgattggtg atatcttctt caagtcaact
     9361 agtctacttg gttatctggc gattgccttc tcattccttg cttggtttat tctctttaag
     9421 actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc ctcaagcagc ggataccttg
     9481 ggaatcaacg tctacaagat gagatattta gggattatta tttcaggttt tctaggtgga
     9541 attggcggag cgatttatgc gcaatcaatc tcagttaact tctcagtgac aactattgtt
     9601 ggacctggat ttatcgccct tgctgcgatg atctttggga aatggaatcc aatcggtgct
     9661 atgctttcta gtctcttctt tggactttca caaagtttgg ctgttatcgg ttctcaattg
     9721 ccgttcctac aaggagtgcc agcggtttat cttcaaattg caccttatgt tttgacaatt
     9781 cttgtcttag cagccttctt tggaaaagca gtcgcaccaa aagcagatgg tatcaactac
     9841 atcaaatcaa aataagcata caaaaaaacg tcagttcaat gactgaactg ccccccaaaa
     9901 gttagacaga aaaaatctaa cttttggggt gtttttatta tgaaactaac ttatgatgat
     9961 aaagttcaga tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa
    10021 tttgggataa acaattctaa tattaggtac atgattaaat tgattgatcg ttacggaata
    10081 gagttcgtca aaaaaggaaa aaatcgttac tattctcctg atttaaaaca agaaatgatt
    10141 cataaagtct gacatgaagg ctggactaaa gatagagttt ctcttgaata cggtctccca
    10201 agtcgtacga tacttcttaa ctggctag
//
LOCUS       DAVLHM010000060        10166 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLHM010000060 DAVLHM010000000
VERSION     DAVLHM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10166
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.060"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            159..634
                     /locus_tag="VXE45_001875"
                     /pseudo
     CDS             159..634
                     /locus_tag="VXE45_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            672..974
                     /locus_tag="VXE45_001876"
     CDS             672..974
                     /locus_tag="VXE45_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0789863.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            982..1783
                     /locus_tag="VXE45_001877"
                     /pseudo
     CDS             982..1783
                     /locus_tag="VXE45_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1832..2296
                     /locus_tag="VXE45_001878"
     CDS             1832..2296
                     /locus_tag="VXE45_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0789864.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2453..2878
                     /gene="lacA"
                     /locus_tag="VXE45_001879"
     CDS             2453..2878
                     /gene="lacA"
                     /locus_tag="VXE45_001879"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0789865.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2909..3424
                     /gene="lacB"
                     /locus_tag="VXE45_001880"
     CDS             2909..3424
                     /gene="lacB"
                     /locus_tag="VXE45_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0789866.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3435..4364
                     /locus_tag="VXE45_001881"
     CDS             3435..4364
                     /locus_tag="VXE45_001881"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0789867.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4366..5346
                     /gene="lacD"
                     /locus_tag="VXE45_001882"
     CDS             4366..5346
                     /gene="lacD"
                     /locus_tag="VXE45_001882"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0789868.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5580..6416
                     /locus_tag="VXE45_001883"
     CDS             5580..6416
                     /locus_tag="VXE45_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0789869.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6452..6769
                     /locus_tag="VXE45_001884"
     CDS             6452..6769
                     /locus_tag="VXE45_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0789870.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6771..8465
                     /locus_tag="VXE45_001885"
     CDS             6771..8465
                     /locus_tag="VXE45_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0789871.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            8674..10080
                     /gene="lacG"
                     /locus_tag="VXE45_001886"
     CDS             8674..10080
                     /gene="lacG"
                     /locus_tag="VXE45_001886"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0789872.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
BASE COUNT         3302 a         1730 c         2090 g         3044 t
ORIGIN      
        1 gcttggagta tttgtttgtg tgtttatttt tatataacaa actataaaca caacaaaaat
       61 ataaaaaaag agacaaaaaa gaacagaaag taattaacaa cgatttcata tagtgttata
      121 cttatagcat aaagttaatg gaaagaaggg aaaaccttat ggtattagat tatttctttg
      181 acaaaaacct tgtgttttgc ttagaagcgg ataatcaaga ataactcttt gatcaggtag
      241 caagcttgtt ggaggaacga gaaattgtaa ctccaactta tcgtgaagct ttgatcacgc
      301 gtgaaaagtc atttccaact ggtttagata tggaatttct aggaaaggac ttgcaaatgt
      361 aatgattcct cacacagata ttgttcataa tctagctgag aaagtggtgg ttgttcgatt
      421 agagaaaccg gtgactttcc ataatatgat tgcgccaggt aaggaagtag aagtatcctt
      481 gctcttcttt atcatcaata attcaagttc aagtcaaacg aacattcttg ctcagttgat
      541 ggactttttc acaggaaatg gacatcttga agacctatca aaaatttccg aaccagaaaa
      601 actttatgct tatatagatg aagcaatcgc ttaatcttgt ctattaaaaa ataaaatcgg
      661 aggaagtcta tatgattaaa attcttgctg cctgcggtgc aggtgttaac tcaagtcacc
      721 aaattaaaag tgctctagaa gaagaacttt caaaccgtgg ttacgatgtt cactgtgatg
      781 cagttatggt gaaagatgta aacgaagacc ttatgaaagg ttacgatatc tttacaccaa
      841 tcgctgcaac agaccttggt tttgaaccag gtatcccagt tatcgaagct gggccaatct
      901 tattccgtat cccagcaatg agcgttccag tatttgacaa tattagactt cctgcgaaac
      961 aaaatatggt atagtagttc tatgaatgat gaagcaagta aacaactaac tgatgcacga
     1021 tttaagcgtc ttgttggtgt tcagcgtacc acttttgaag agatgttagc tgtattaaaa
     1081 acagcttatc aacttaaaca cgcaaaaggt ggacgaaaac ctaaattaag cctagaagac
     1141 cttcttatgg ccactcttca atagtgcgag aatatcgaac ttatgaacaa attgcggctg
     1201 attttggtat tcacgaaagc aactttatcc gtcggagcca atgggttgaa gtaactcttg
     1261 ttcaaagtgg tgttacggtt tcaagaactc ctctcagctc tgaggacacg gtaatgattg
     1321 atgcgacgga agtacaaatc aatcgcccta aaaaagaatt agcgaatgat tctggtaaaa
     1381 agaaatgcca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga ttgtttcttt
     1441 ggatatcact gtgaactatt gtcatgatat gaagttgttc aaaatgagtc gcagaaatat
     1501 cggacaagct ggtaaaatct tggctgacag tggttatcaa gggctcatga agatatatcc
     1561 tcaagtacaa actccacgta aatccagcaa actcaagccg ctaacagttg aagataaaac
     1621 ctataaccat gcgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
     1681 aacgtttaaa atgatttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat
     1741 gaatttgatt gctggcatta tcaatcatga actaggattc tagttttgca ggaagtctaa
     1801 taaagaaact agcaaggtca ggccttactt tattggtgga catccaggat ttaattgtcc
     1861 tctacttgat gatgaagtct atgaagatta ttatctagag tttgagaaag aagagacttg
     1921 ctctgttcca cgtcctttcc cagaaacagg tatgttggat ttccaagata gaagtccatg
     1981 gctagaggga caaaaagaaa tagatcttag ttatgatctt ttcagcaaag atgcagtgac
     2041 tttggatgaa ttgcaatctc gaacaattgc ccttcgttct cttaaacatg ataggggatt
     2101 gaaagtgcat tttgcagaat ttccaaacct catcatctgg tcaactttga acaagggacc
     2161 tttcattacc tttgaaccat ggtctggctt gtcaacattc cttgaagaag gagatcattt
     2221 agaagataag aagaatgttt gtctcttaga agccaatcag gttgaagaat tagggtttga
     2281 gatagaagtt ttataaaaaa gtaaaaaata aataacaaaa acaaacacaa actgttgact
     2341 tcttcaaaca atagtagtat attatgtttg tgaggactaa ttgactgttt tttaaagaca
     2401 gccaatacac tgctggaatc cagcatagaa aaaataaaaa ggagtataca atatgtctat
     2461 tgttatcggt gcagatgctg caggtttgag attgaaagaa gttgtgaaag acttcttaga
     2521 aaaagaaaac ttccaccttg tggatgttac agctgaaggt caagactttg ttgatgtgac
     2581 tctcgctgtt gctgcagaag taaacaaaga agaacaaaac cttggtatcg tgattgatgc
     2641 ttatggagct ggtccattta tggttgcaac taagatcaaa ggaatggttg ctgcagaagt
     2701 ttctgatgaa cgttcagctt atatgactcg tggccacaac aactcacgta tgatcactat
     2761 gggtgcacaa cttgttggtg atgaattggc taaaaacatc gctaaaggat ttgttaatgg
     2821 taaatacgac ggtggtcgtc accaaatccg ggttgacatg ttgaacaaaa tgggctaatt
     2881 agattatagt aagaaaggta agttaaaaat gagaattgca attggatgtg accacatcgt
     2941 aacagatgaa aaaatggcgg tttcagaatt tttgaaatca aaaggatatg aagtcattga
     3001 ctttggtaca tatgaccata cacgtactca ctacccaatc tttggtaaaa aagtagggga
     3061 agctgtaact agcggtcaag ctgatcttgg agtatgtatc tgtggtactg gtgttggtat
     3121 caacaacgct gtaaataaag ttccaggtgt tcgttctgcc ttggttcgtg atatgacaac
     3181 agccctttat gctaaagaac aattgaacgc taacgttatt ggttttggtg gtaaaattac
     3241 tggtgaattg cttatgtgtg atatcatcga agctttcatc catgctgaat acaaaccaac
     3301 tgaagaaaac aaaaaattga ttgcgaaaat tgaacatgtt gaaagtcaca atgctcaaca
     3361 aacagacgca aacttcttca ctgaattcct tgaaaaatgg gatcgcggag aataccacga
     3421 ctaagaggta acctatgatt ttaacagtta caatgaaccc atccattgat atttcctatc
     3481 ccttggatga gttgaagatt gatactgtca atcgtgtggt ggatgtaacc aaaacggctg
     3541 gtggtaaggg actcaatgtt acccgagtac tttcagaatt tggcgattct gttcttgcta
     3601 ctggtttagt gggtggcaaa cttggtgagt ttttggttga acatatcgat aatcaagtaa
     3661 agaaagattt cttctcaatt cagggagaaa ctcgtaactg tatcgctatt ctccacggag
     3721 acaaccaaac agaagttctt gaaaaaggtc ctgaagtatt ggaacaggaa ggtcaagact
     3781 ttttggaaca tttcaaaaaa ctcttggagt cagttgaagt agtggccatc tcaggtagtc
     3841 tgccagctgg ccttccagtt gattactatg cgagcttggt agaacttgct aatcaagctg
     3901 gcaagcctgt agtcttggac tgctcaggtg cagcacttca ggctgttctt gaatcacccc
     3961 ataaaccaac agtcatcaaa ccaaataatg aagaattgtc tcagcttctt ggaagagaag
     4021 tttctgagga tttggatgaa ttaaaagaag tacttcaaga acctttgttt gcagggattg
     4081 aatggattat cgtttcactt ggtgccaacg gtacttttgc caaacatggt gacactttct
     4141 acaaggtaga tattcctaga attcaggtgg taaatcctgt tggatctgga gactctactg
     4201 tggcaggaat ttcttcagga cttcttcaca aagaatcgga tgcagaatta ctcatcaagg
     4261 caaatgtcct tggtatgctc aatgctcaag aaaaaatgac tggtcatgtc aacatggcca
     4321 actatcaagt tctatatgat caattaatag taaaagaggt ataaaatggc tttaacagaa
     4381 caaaaacgtg tacgcttaga aaaactttct gatgaaaatg gtatcatctc agctcttgca
     4441 tttgaccaac gtggtgcttt gaaacgcctc atggctcaac accaaacaga agaaccaact
     4501 gtggcccaaa tggaagaact taaagtcttg gtagcagatg aattgactaa atacgcttca
     4561 tctatgcttc ttgaccctga gtatggactt ccagcaacta aagctcttga tgaaaaagct
     4621 ggtcttctcc ttgcttatga aaaaacaggt tatgacacaa caagcacaaa acgcttgcca
     4681 gactgcttgg atgtctggtc tgcaaaacgt attaaagaag aaggtgcaga tgcagttaaa
     4741 ttcttgcttt actatgatgt agatagctca gacgaactca atcaagaaaa acaagcctac
     4801 atcgaacgca tcggttctga gtgtgtggct gaagatatcc cattcttcct tgaaattctt
     4861 gcttacgatg aaaaaattgc ggatgcaggt tctgtagaat acgcgaaagt aaaaccacac
     4921 aaagttatcg gcgctatgaa agtcttttca gacccacgct ttaacattga tgtcttgaaa
     4981 gttgaagttc ctgttaacat taaatatgtt gaaggcttcg ctgaaggtga agtagtttat
     5041 acacgtgaag aagcagcagc cttcttcaaa gcgcaagatg aagcaacgaa cttgccatac
     5101 atctacttga gtgctggtgt atcagctaaa ctcttccaag atactcttgt atttgctcat
     5161 gaatcaggtg caaactttaa cggagttctt tgtggccgtg caacatgggc tggatcagtt
     5221 gaagcataca tcaaagatgg tgaaacagca gctcgcgaat ggcttcgcac aactggattt
     5281 gaaaacattg atgagctcaa caaagttctt caaacaacag caacttcatg gaaagaacgt
     5341 gtgtaagaaa gtcctcctag tttaggaaca tgaatctaaa aaaatttaaa aaaagttgta
     5401 tgtaaaggtt tacaaaataa cttacttgtg ctatacttaa atcacaagtt aatacaaggt
     5461 gagtgttact aagtaatatt aggcatgatc acaggtgaat tagaaatcag ctgattttct
     5521 agttcatttg tggtcatttt ttgtactcat atacctttaa gatataaaag gaggttgaca
     5581 tgtatcgaat tctaaatcca atgaatcaca atgtctcgct tgtcagaaat gataagggag
     5641 aagaggtgat tgtaattggt aaggggattg cattcggaaa gaagaagggg gatttgattg
     5701 ctgaaaatca tgttgagaaa atctttcgga tgaagaccga agagtccaga gaaaacttta
     5761 tggctcttct caaagatgtt ccgcttgatt ttatcacagt gacctatgaa atcattgata
     5821 agctatcaaa gaaatatcat tatccgattc aagagtatct ctatgtaacc ttgacagatc
     5881 atatttactg ttcttatcaa gctctaactc aaggaaggta caaggatagt aatctgccag
     5941 atatttctgc taagtatcct gtcgcttttc aaatcgcaaa tgaagctttt gaaatttact
     6001 gtcagaagct agcagatcat tttcctgagg acgaaattat tcggattgct tatcatttca
     6061 ttaatgctga aggtgaaaat gaagtggaac ttgtggagtc gattgataag aggaaagaaa
     6121 ttctcaggaa tgttgaagaa gttttaacgg actatgcaat tcaacgaact aaaaagaata
     6181 accatttcta tgatcgcttt atgatccatt tgaattattt cttggattat ttagacagat
     6241 ctagagatga taaccaatca cttctggata tggaagatca tattaaacaa tcctatccaa
     6301 aagccttcga gattggttcc aagatctatg atgtgattac gcaacatacg ggtcttgatt
     6361 tgtataaaag tgaacgagtt tatctagttc tacatatcca acgtttattg tcataaaaat
     6421 ttatttaaaa ctatataagg agaattctat catgaataga gaagaagtaa cattgttagg
     6481 ttttgaaatc gtagcctatg ctggcgatgc tcgttcaaaa ctattggaag ccttgaaggc
     6541 tgctgaagct ggtgattttg aaaaagcgga cgctctggta gaggaagctg gtagctgtat
     6601 tgcagaggct caccacgcgc aaacaagtct attgactaag gaagcttctg gtgaggactt
     6661 agcgtatagt gtgaccatga tgcatggtca agatcacttg atgacaacta tcttgttaaa
     6721 agacctaatg caccatttaa ttgaacttta caagagagga gttaaataaa atggataagt
     6781 taataatttt tattgagaaa ggaaagcctt tctttgagaa attatcgaga aatatatact
     6841 taagagcgat aaaagatggt tttatttcca gtatgccagc agtattattc tcaagtattt
     6901 ttatactaat agctgctgtg cccaatattt ttgggtttaa atggtctgat gaacagttag
     6961 cttttatttt gaaaccttac aactactcaa tggggatttt agctctctta gtagctggga
     7021 caactgcaaa atcgttaaca gattcagtta atacacgtag tatggagaaa accaaccaaa
     7081 tcaactacat gtcaactttt ttagcagctg ttgttggatt gttaatactg gcagctgatc
     7141 caattgaagg tggatttgct aatggtcttt taggtactag aggattactt actgcatttt
     7201 tggcagcttt tattacagta aatatctata aagtatgtat taaaaataat gtaaccatta
     7261 gacttcctga agaggttcca ccaaatattg cacaagtttt taaagatgtt attccgtttg
     7321 ccttatctgt tctttcaata tatggattgg atttaattgt tagaaatatt tttggtacaa
     7381 atgtagcaga atctgttggt aaaatattag cccctctatt ttcagctact gatggttata
     7441 tcggtttagc tattgtattt ggtgcttatg ctttcttttg gtttgttgga attcatgggc
     7501 catctgttgt agaaccttta attgtagcta tcagttatgc aaatatagaa gctaatgttc
     7561 agcttgtgca agctggtatg cacgcagata aaattttaaa tccagttact caaacttttg
     7621 ttgtaacaat gggtggtact ggtgcaacac tagtagttcc atttatgttt atgtggttat
     7681 gtaaatcaaa aagaaataga attgtcggac gtgcgtctgt agttcctact ttctttggcg
     7741 taaatgaacc aatcctattt ggtgctccaa ttgttttaaa tcctatcttc tttattccgt
     7801 ttgttactgc tcctattatc aatgtttgga ttatgaaatt ttttgtagat gttctacaaa
     7861 tgaatagttt cagtattatt ttaccttgga caacacctgc tccaattggt attgttatgg
     7921 gaacggcgct ggctccattg tcattcgtct tggctataac tttaatcatt atcgacactt
     7981 taatctatta tccatttgtt aaagtttatg accatcaaat tttagaagaa gaacggaaag
     8041 gaaactcttc atctgaattg aaagaaaaag ttgctgcaaa cttcaacact gcaaaagcgg
     8101 atgctattct tgaaaaagcg ggtgtagaag cagcacaaaa tacaatcact aaagaaacaa
     8161 atgtcctcgt tctctgtgca ggtggaggaa caagtggtct ccttgcaaat gctttgaata
     8221 aggcagcagc agaatacaat gtccctgtga aagcagcagc aggcggctat ggtgctcacc
     8281 gtgaaatgtt accagagttt gatcttgtta tccttgcccc tcaagttgct tcaaactttg
     8341 aagatatgaa agcagaaaca gataagctcg gtattaaact agcgaaaaca gaaggcgctc
     8401 aatacatcaa attaactcgt gatggaaaag gtgctcttgc attcgtacaa gcgcaattcg
     8461 attaaggcta gagactctga aatagtctcc tatcgttacg gaaatcgcta tggcgaattt
     8521 cctattatta attcgtcggt aaaaagatat cgtttttacc tcctcatgtc acaattcggt
     8581 gacttggtac aagaagtgag atggagaagg atggctcatt gactcctctc ctctcacttt
     8641 tactttattt aaatcaagaa ataggtgaaa aaaatgacaa aaacacttcc aaaagacttt
     8701 atttttggtg gcgcaacagc tgcctatcaa gcagaaggtg ctacacatac tgatggtaaa
     8761 ggaccagtag cgtgggataa atatcttgaa gataactact ggtacactgc agaaccagcc
     8821 agtgattttt acaatcgata tccagttgac ctcaagctag cagaagagta tggtgtcaat
     8881 ggtattcgaa tttctattgc ttggtcacgt attttcccga ctgattacgg ccaagtaaat
     8941 gctaaaggtg ttgagtttta tcataattta tttgcagagt gtcacaaacg tcatgttgag
     9001 ccttttgtaa ctcttcatca ctttgacacg ccagaagctc tccactcaaa tggagacttc
     9061 ttaaaccgtg aaaatatcga acattttgta gactacgctg ccttctgttt tgaagaattt
     9121 ccagaagtaa actattggac aacctttaat gaaattggac caatcggtga tggtcaatat
     9181 ttggttggga aattccctcc aggtatccag tacgaccttg ccaaagtctt tcaatcacac
     9241 cacaatatga tggtgtctca tgcacgcgcg gtaaaattgt acaaagagaa aggctataaa
     9301 ggggaaattg gtgttgttca cgccctgcca actaaatatc ctctagatcc tgaaaatcca
     9361 gcagatgttc gtgcagctga gttggaagat atcatccaca ataaattcat cttagacgca
     9421 acttatctag gtcgctattc agctgaaacc atggaaggtg tcaaccatat cttatcagtc
     9481 aatggtggta gcttggatct tcgtgaagaa gattttacag cattagaagc tgcaaaagac
     9541 ttgaatgatt tcctaggaat caactactat atgagtgact ggatggaagc ctttgatgga
     9601 gaaactgaaa ttatccataa tggtaaaggt gaaaaaggaa gctctaagta tcaaatcaaa
     9661 ggtgttggtc gtcgtgtagc tcctgactat gtaccacgca cggattggga ttggattatc
     9721 taccctcaag gtttgtatga ccaaatcatg cgtgtgaaga aagattatcc taactacaag
     9781 aagatttaca tcactgaaaa tggtctcggc tataaagatg agttcgttga taacactgtt
     9841 tacgatgatg gtcgtattga ttacgtgaaa caacacttgg agatcttgtc tgatgcgatt
     9901 gcagatggag ctaatgtaaa aggttacttc atttggtcat taatggatgt cttctcatgg
     9961 tcaaacggtt atgagaaacg ttatggtctc ttctacgtag attttgaaac tcaagaacgt
    10021 tatcctaaga aatcagctca ctggtacaag aaagtagcgg aaactcagat tatagactag
    10081 tagaattagt cattagatat agaattttag tgagtcaaaa agatgttcaa agattttatc
    10141 caatctattt atgaaaaaaa gtttat
//
LOCUS       DAVLHM010000061         9744 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLHM010000061 DAVLHM010000000
VERSION     DAVLHM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.061"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            342..950
                     /locus_tag="VXE45_001887"
     CDS             342..950
                     /locus_tag="VXE45_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789873.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(1037..1240)
                     /locus_tag="VXE45_001888"
     CDS             complement(1037..1240)
                     /locus_tag="VXE45_001888"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789874.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(1537..2241)
                     /locus_tag="VXE45_001889"
     CDS             complement(1537..2241)
                     /locus_tag="VXE45_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0789875.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(2311..4137)
                     /gene="glpO"
                     /locus_tag="VXE45_001890"
     CDS             complement(2311..4137)
                     /gene="glpO"
                     /locus_tag="VXE45_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0789876.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(4179..5687)
                     /gene="glpK"
                     /locus_tag="VXE45_001891"
     CDS             complement(4179..5687)
                     /gene="glpK"
                     /locus_tag="VXE45_001891"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0789877.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(5846..7273)
                     /locus_tag="VXE45_001892"
     CDS             complement(5846..7273)
                     /locus_tag="VXE45_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0789878.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            7438..8310
                     /gene="hslO"
                     /locus_tag="VXE45_001893"
     CDS             7438..8310
                     /gene="hslO"
                     /locus_tag="VXE45_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0789879.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            8297..9277
                     /gene="dusB"
                     /locus_tag="VXE45_001894"
     CDS             8297..9277
                     /gene="dusB"
                     /locus_tag="VXE45_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0789880.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(9507..>9744)
                     /locus_tag="VXE45_001895"
     CDS             complement(9507..>9744)
                     /locus_tag="VXE45_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV0789881.1"
                     /translation="GWLQNNGSWYYLNANGDMATGWVKDGDTWYYLEASGAMKASQWF
                     KVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT         2770 a         2229 c         1937 g         2808 t
ORIGIN      
        1 aaatacgtct atttattttt tattgttttt tattgtagag cagacccaag cgaatgaaca
       61 taggttgtaa aaagcaaatg aaaaaactgc gaggataata gcttctgtgt ctaaataacc
      121 catttcgaga cctcttttca acaacaacaa gcctgtagtt tcgataacga tcaaacataa
      181 aaatatataa aaaattttcg cattaagcat attgttaccg ctttcttttt atttggtttt
      241 attgtataat aaaagttgaa aaaaatcaaa aatacaaaag agtttccgtt atgtctaaga
      301 tgtttaaatg catgtgtttg ctagttatgt ctgttttctg tatgtctagc atttccccgt
      361 cgcttgttgt ttttgctgat gatagcttat cggcaaactc taaagttgta tctggtgagg
      421 ctcagtttga gaatggctca tcagtgcggt tcggagatac gcaagtaaat attttaagcg
      481 atgaagttct tgaggttgtc aatccagatg gaagtgtaga cactattgaa cgacgtgctg
      541 acggcgtcta tatcaatggg gcattttata tggcttatca aaagaatgaa atcgacctaa
      601 atatatcttt tagatcatac gatcctaatg tttggaatta cgtcaacaca atacatggga
      661 ataaacaagc taacacattc gctaacttca tgactggtgc tggaatcagt tatatgattg
      721 gtaggatagg tgctttattg gggggtccat ggggtgcaat aattggtgga gcatattttg
      781 gtatacaagc ttatcagtct tacttggatt cacaaagccc atatccatac tacataacaa
      841 gtacttatat ccatgttgct caaagaaaat ggaagtttat cactgaatac tatagaaact
      901 caaactatac tgggtatgta aaaaccgtaa caacctacgt gaatttctaa aatataaacc
      961 ctgcctttat atctaggcag agtttatatt ttagttaatt gctcaagtaa tttgtaagca
     1021 taatacttgc gaaactctat ttgttcaagc ggttcaaaag ctcttgtttt ttaccctcaa
     1081 gctcagctct cctttgctcg atttcttcac gtttttgggc gatttctgct tgcgcctcgg
     1141 gagtttccaa agtgccttgt gacttgtgaa attctactag catatcaacg atttttgggt
     1201 ctaattcgtt gacataatca ggatttgacc atttcggcac gttgcttgca ggtgcttgct
     1261 ttttgccgcc ttttttgggc gttttggctt gttgttcagc tttctgactg tagttgacct
     1321 cgtggaattt tcgtgcttga tatgatgcgt tttattatga gaagatttac ttcatttttt
     1381 gctgaaattg ggctcttgcc caagctctat caacataatt gttttctaat actcaatgaa
     1441 aatcaaagag caaactagga agctagccgc aagctgtact tgagtacggt aaggcgacgc
     1501 tgacgtggtt tgaatttgat tttcgaagag tataaactag aaaagtgaga atacaagcac
     1561 tgccaaggct gctccgataa cagggcctac aacaggaatc caagcgtaag accagtctcc
     1621 gtctcccttg tttggaattg gcaagatgct gtgcatgata cgaggtccaa ggtcacgagc
     1681 tgggttcaag gcataacctg ttgtcccacc tagtgataga ccgataccga caatcaaagt
     1741 tcccactgca aaggttccga tacctgcctg aaaatcgtaa agacccaaag caaagattgt
     1801 caacaccaaa acaaaggttc caaggatttc gctaatcaag tttgatacag tatccttgat
     1861 ggctggtcca gtactgaagg ttgccaggat attgcctgca ttttcttctg cctcatagtg
     1921 aggtttgaat tgcaaccaaa ccaaaatctg acccagcatg gcccctgcga actgggctaa
     1981 gatataaggc aaaacggaag cccaaggcaa gtcacctttt aaagctacac caactgtcac
     2041 agctggattt aaatgagctg gactgagctt gccagataca aagactgcaa ccgcaactgc
     2101 aatcccccaa cccatagtaa tcacaatcca acctgagcta ttgctcttgg ttttaggaag
     2161 aaccacacct gcaacaacac catttcctag aagaatcagg attaaagtcc ctagaaattc
     2221 tccaaataat tcattcatca tctttctgtc tccattaaaa agaagggacg ggcgacaagg
     2281 aatgctgccc tccacctctt ttattttttc ttaatttttt aattctgcta aatcgttgtt
     2341 agcgagagct gcttcgacat cagcacggta agttgctttt tcttcttctg tccagtcata
     2401 gaatcgtccc atttcatcca aaactggctc aacgatgcta tccaagctat cacgcataaa
     2461 gagcatatgg ttggtacgac gaagaaggaa gtcaactggg ctaagagcca actcgttgcg
     2521 cattgcatag tgaagggaca aggtatctgc caagctgagt cctggcgctt gttccaagct
     2581 gtgagcaagt gcaaagactt tcggtgcatt tgaaccgtaa agatttgcca gatagtgagc
     2641 ttccttgcta tccaaaccac gtgatactcc aagttgcgca aaggcttcga tttctgaatc
     2701 cacatttgct gggttcaatt ctccacctga aacagggtaa gttttagaat tgatcaattt
     2761 aaagctacgg tcaaattctg ctttgaggat gtcaaccacg cgctccatag ctccttcagc
     2821 catcttacgg tagtctgtga ttttaccgcc agcaagagtc aaaagaccat tgtcatcacg
     2881 gtccaagcta gacccacgag aaactgcaga tggatccaaa tatttctcag atgtgctact
     2941 ttcaagcttg ctgacagcag actcaacatc ttcacgtgtt ttttctttgg agagataaga
     3001 ttcaacagtc gcaatcaagt tgtcaaagct ttcatcactg atggtaccgt tatttccacc
     3061 attatagtca gaggcactgt tccctgcaat caatggacga agacctgccc agctgctttc
     3121 gatatcatca atggtgatgt tggattctgg aaagcggttg ttgacaatgc caagtagata
     3181 atctacatct tcttgagtta cttttggatg ctccaaatca cctgtgtagt ctgtatcagt
     3241 tgtaccaaag taagtcttgt tttcacgtgg gagaacaaag accatacgac cgtcacccaa
     3301 acctgtgtcg aagtaaactg gctgtgaaac cttgattttg cttgaatcca ctaccaagtg
     3361 aactccctta gttgggcgca tttgtgagaa ttgcgttccc ttattagaca aattacgtac
     3421 tttatcactc caaggacctg ttgtattaat aaccagacgg gccttgattt caaatacttg
     3481 gtctgtcaag agatcacgag ctacaacacc tgtaatcttg ccactttcgt caaagaggaa
     3541 gccttctgcc ttcacgtggt tggcaatgag ggcaccgtct tggttggcac gtttgatgtt
     3601 ttcaatcacg agacgcgcat cgttgttacg gaagtcaaga tacactccac ctcctaccaa
     3661 gccttccttc ttcaagtttg gctggcgttc caagacttct ttcttgctca aaaccttgtt
     3721 cgcagttggt gtgttgctaa cacctgccaa aaggtcgtac aagtccatgg ctactttgag
     3781 acggaagagg ctaaaggttg ctccatcttc atcgtaaact ggtaagagca ttgggtctgg
     3841 ttttggaatg tgtggagcga tttgttgaac cactgcacgt tcagaaaccg tatctgagac
     3901 cacttctacg tcaaattgtt tgaggtaacg aagtcctccg tgaaccaatt ttgttgaacg
     3961 actagatgtt ccttctgcaa agtcttgcat ttcaatcaaa ccagtctcaa gaccgctagc
     4021 tgccgcctgc aaggctacac cagctcctgt gattcctcca ccgataatca agaggtccag
     4081 ggtgcgttcc tgcatttttt taattgacaa ttcacgtgtt ttctttgaaa attccatatt
     4141 tacacacttt ctaaataaat cgctttattc tgccagtatt agtcgtctac ttccgcaaag
     4201 acttgagttg ctttcacagc cttcttccag cccttgtaga gttgttcctt gcgagattcg
     4261 ttcatagatg gctcaaagag ttctcctgtc tcgttcaaga gtttcaactc gtccaagtct
     4321 ttccaatacc ctactgataa acctgctagg aaggccgctc ctagagctgt tgtttccaag
     4381 tttttagcac gtgcaatatc aatgcctaaa atatccgcct ggaactgcat gaggaagttg
     4441 ttcatggctg caccaccatc caccttcagt acttgaatgg cggtctgagt atccacttgc
     4501 atggtgtcga tgatgtcacg cacttgataa gcaatagatt gcaaagtcgc cttgataaag
     4561 tcttctttgc ttgttccacg agtcaaacca aagacggaac cacgagcatt ttggttccag
     4621 tatggagcgc ctagacctgt aaaggctgga acgacataaa cttcatcgtt gttgtgagaa
     4681 tcacgagcgt atttttcaga ttctggtgaa ttttcaacca tgcgaagacc gtcacgaagc
     4741 cactgaatag cacttcctgc gatgaagata gaaccttcca aggcataata aaccttaccg
     4801 ttgattccgt aaccaatggt tgtcaagagg ttgttttcag acaactgcat ctcttcccca
     4861 gtattcatga tgatgaaaga gcctgttcca taagtattct taaccatacc tggctcaaaa
     4921 gccaactgtc caaagagggc tgcttgttgg tccccagcca tacctgagat tggcacctct
     4981 ccaccgtaga aatggaatgg agctgtcttg ccgtagattt cggagttaga acgaacttct
     5041 ggaagtatag ccttcggaat gttaaggatt tccaaaatct catcatccca tttgagttct
     5101 ttaatgttat aaagcatggt acgagctgca tttgagtagt cagtcacgtg agccgcaccg
     5161 tcagtcaatt tccaaaccaa ccaagtatcg atagtaccaa agagcaattc ccctttttct
     5221 gctcgctctt gagcaccttc tacatgatcc aaaatccaac gaaccttggt agcagagaag
     5281 taagcatcaa taatcaaacc agtcttttca tggaattttt ccacataacc ttggcttttt
     5341 agttgctcag ccaaaggtgc tgtctggcgt gactgccaaa cgatagcatt gtagatagga
     5401 agtcctgttt tcttatccca gacaaccgtt gtttcacgtt ggttggtaat cccgattgcc
     5461 tcgatttgat ttggcttgac accactttcg atgaaagcac ccgcaataac tgactgaaca
     5521 gagttccaaa tttcattggc attgtgctca acccaacctg cctgagggaa aatctgggta
     5581 aactcttttt gactcgagct aaccttttcc ccttttttgt tgaaaatgat ggcacgagaa
     5641 cttgtagttc cctggtcaat ggccatgatg tatttttctt gtgacatgta ctgtcctcct
     5701 gataaagatc ttgaggtgtt tcctctttac acttactagt atacaaaata aagcgctttc
     5761 ttgtttatca acttttttta atttttaaaa aaatgtgagg agattgtgtg aatttcacaa
     5821 aaaagacctg gattaaccaa gccttttaag tgaataataa ctgacgaatc cctgccaaat
     5881 cttccatatc caagtcgttt tttaaataat agactggtgt ctgttccttc ttatgaatcg
     5941 ggttattggt aaccagcaaa tcataatgcc gactagggtc ataagcttca atggtaataa
     6001 aacgattgta ttccaaatac cgtttcaaaa tggctgccat ccttgaaaag acaagaaaac
     6061 cagatgtcaa atccagacca atccgcatat gctggccacc gttttcagcc atatattcga
     6121 ttaactggag ccattcccag agaatcttct tatctaaatc tgtcccctgt tgaaaagcag
     6181 gtagagcatg aaaaatctcc tctgctgtct ctttaaaatc atgttccatc agtaaatatg
     6241 gatgacgatt ctctaactgg tacttgtagc gatcctgtaa aatatagccc ttatagagat
     6301 agacttgagc acaaagctga ctgagttcat aggtgacatg gtcctctgta taatccccca
     6361 atagttcctc cttcttcatt tcttgaatca attgcgtcag taaatctgcc aactgccctc
     6421 caaaaccaag aatatactcc atagtatgaa gaggaagaat gcgatgagat aggagaaaag
     6481 agaagaatat catcatctca ccatcctcaa ctcctagtgg aatatgttgc ccagcaaaaa
     6541 aggacggaac ctttctcagc aaacgaaggt agaaaatatt gtcaaaatac cctcgcattt
     6601 tctcttctat gacttgaaac tgacaagcat tgacccgaag acgttgttga ctgatgtgag
     6661 cccagagaac caagtccaat ttctgcccca cagacaaact tgcaccgcag atttcctcta
     6721 aattggcaat ctcctgtttt ctctctggtt tctgcatgtg accttcccat tcctgactcg
     6781 accagacctt tcggaaaaga cagaaataga aatagcgaat ctgatgctct ggacctcgcc
     6841 aacgtccatt ttggatggat aaatcaaatt ctgacaaaat ctgatttaaa ccagccaagt
     6901 gacgaccaag cgtagcctcg ctaatcacca attcttgagc cagctgatgg gctaaaaact
     6961 gttggtggta gagaagataa accaaaatct ggtatttaac agcactctcc aaaaacaagc
     7021 tccgaatatc tctccccttg gtagctgcac cgatagacag acgcagattt tcatcttctg
     7081 agtgaatagc cagctctaag ccactatcca aagccttgtc attgagcagg gtgacatatt
     7141 tggttagggt tgcttttgaa aatcctgttt cttccattac agccttgacg gtcgtctgag
     7201 actcttgtaa tagaaaggaa aggattgaaa attgaccaca ctcggctttc tccatcaaat
     7261 ctcctaaata catttgttac ccctttcatt ttctacctta agcatagcat aaatcttaca
     7321 aatgctgaaa taatctgttt ctctttttat tttcatgctg atttcctggt ccattatcct
     7381 gaaaatcagt aaacacacgg ctcccccttt gggcattttt atgctaaaat agtagctatg
     7441 gataaaatta ttaaaactat atcagaaagc ggagcctttc gtgcttttgt ccttgatagc
     7501 acggaaaccg tccgcactgc tcaagaaaaa catcaaaccc aagctagctc aactgtagcg
     7561 cttggtcgaa ctcttatcgc cagccagatt ctcgcagcca atgaaaaagg aaataccaaa
     7621 cttacagtta aggtgttggg ctctagctct ctaggtgcta ttatcaccgt cgctgatacc
     7681 aaggggaacg tcaaaggcta tgttcaaaat cctggtgttg acatcaaaaa gactgcgact
     7741 ggtgaagtcc tagtcggacc ttttgttgga aatggtcaat tcctcgttat cacagactac
     7801 ggtgctggaa atccttacaa ctctataact cccctcatct ctggagaaat cggtgaagac
     7861 cttgcctttt accttactga aagccaacaa acgccttcag cggtcggcct caatgtcctt
     7921 ttggacgagg aagacaaggt caaggttgca ggtggtttcc tagttcaagt cttgccagga
     7981 gccaagaaag aagagattgc tcgctttgaa aaacgcatcc aagaaatgcc agctatctct
     8041 actcttctcg aaagcgacga ccatatcgaa gccctcctca aggctatcta cggggacgaa
     8101 gcctacaagc gtctttctga agaagaaatc cgtttccaat gtgactgtag ccatgaacgc
     8161 tttatgaacg ctcttgccag ccttccaagc tcagacttac aggaaatgaa agaggaagac
     8221 cacggggcag aaatcacttg tcaattctgc caaactactt acaactttga tgaaaaggac
     8281 ctggaggaac tcattcgtga caaatcttaa tacacctttt atgattggca atattgagat
     8341 tcccaatcgt accgttttag cgcctatggc tggcgtgacc aactcagcct ttcgtaccat
     8401 cgcaaaagag ctcggagctg gactcgttgt aatggaaatg gtctctgaca agggaatcca
     8461 atacaacaac gaaaaaaccc tgcacatgct tcatatcgat gagggcgaaa accctgtctc
     8521 tatccaactt tttggtagcg atgaagacag cctagcacgc gcagcagaat tcatccaaga
     8581 aaacaccaag accgatatcg tcgatatcaa catgggctgc cctgtcaaca aaatcgtgaa
     8641 gaacgaagct ggagctatgt ggctcaagga tcctgacaag atctactcta tcatcaacaa
     8701 ggtccagtct gtccttgata tcccacttac tgtcaaaatg cgtaccggct gggcggaccc
     8761 atctctggca gtagaaaatg ccctcgctgc tgaggctgca ggtgtttctg ccctcgccat
     8821 gcatggccgt acccgtgaac aaatgtatac tggccacgca gaccttgaga ccctttacaa
     8881 ggttgcccaa gctctaacca agattccatt catcgccaac ggtgatatcc gtactgtcca
     8941 agaagccaag caacgcatcg aagaagttgg tgctgacgca gtcatgattg gccgagctgc
     9001 catgggaaat ccttacctct tcaaccaaat caaccattac tttgaaacag gagaaatcct
     9061 acctgatttg acctttgaag acaagatgaa gatcgcctac gaacacttga aacgattgat
     9121 taacctcaaa ggagaaaacg tcgcagttcg tgaattccgc ggcctcgctc ctcactacct
     9181 ccgtggaaca tctggcgctg ccaaactccg tggagccatt tcgcaagcta gcaccctggc
     9241 agagattgaa gccctcttgc aattggagaa ggcttaatag tttaaaaccc gtaactctct
     9301 taaagagcct cttgaatgcc gccattcttt cctcatcaaa aaaactccgt agtctctagc
     9361 gctataaatc cggctagaga ttacagagtt attttttaat ctaaacttcc tacaagggta
     9421 tattatctac tgaaaggata tggtatttgt agggaatact ttaaagagtt cttacaggaa
     9481 gtcagtatta actagttata ttaggtttag tttacccatt caccattggc attgactcca
     9541 tagccatcta cagttgtgtt gactgcaagg gcacctgagc cattgacata gtaccattta
     9601 tctgatactt tgaaccattg gcttgctttc atagcacctg atgcttcaag atagtaccag
     9661 gtatctccat ctttcaccca acctgtcgcc atatcaccat tagcgtttag gtagtaccat
     9721 gagccattgt tttggagcca tcct
//
LOCUS       DAVLHM010000062         9720 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLHM010000062 DAVLHM010000000
VERSION     DAVLHM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.062"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            85..2013
                     /gene="glgB"
                     /locus_tag="VXE45_001896"
     CDS             85..2013
                     /gene="glgB"
                     /locus_tag="VXE45_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0789882.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRKDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATNITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2003..3145
                     /locus_tag="VXE45_001897"
     CDS             2003..3145
                     /locus_tag="VXE45_001897"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0789883.1"
                     /translation="MKNEMLALILAGGQGTRLAKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGIDSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLELGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3135..4274
                     /gene="glgD"
                     /locus_tag="VXE45_001898"
     CDS             3135..4274
                     /gene="glgD"
                     /locus_tag="VXE45_001898"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0789884.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4271..5704
                     /gene="glgA"
                     /locus_tag="VXE45_001899"
     CDS             4271..5704
                     /gene="glgA"
                     /locus_tag="VXE45_001899"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0789885.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5763..6134
                     /locus_tag="VXE45_001900"
     CDS             5763..6134
                     /locus_tag="VXE45_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0789886.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVPGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6174..6407
                     /locus_tag="VXE45_001901"
     CDS             6174..6407
                     /locus_tag="VXE45_001901"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0789887.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCSKEMLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            6416..7532
                     /locus_tag="VXE45_001902"
                     /pseudo
     CDS             6416..7532
                     /locus_tag="VXE45_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(7529..7975)
                     /locus_tag="VXE45_001903"
     CDS             complement(7529..7975)
                     /locus_tag="VXE45_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0789888.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8139..9443
                     /gene="eno"
                     /locus_tag="VXE45_001904"
     CDS             8139..9443
                     /gene="eno"
                     /locus_tag="VXE45_001904"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0789889.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
BASE COUNT         2908 a         1743 c         2154 g         2915 t
ORIGIN      
        1 agaagtatag taatttactt gaatcttctc taaaaaggta gtataataaa aacatagaaa
       61 acgcttacag gagaaaggga gtatatggat aatagagaag cattaaaaac ctttatgacg
      121 ggtgaaaatt tttatctcca acattatcta ggagcacata gggaagaact aaatggagag
      181 tatggctata ccttccgtgt ttgggcacct aatgctcagg ctgttcactt ggttggtgat
      241 tttaccaatt ggattgaaaa tcagattcca atggtaagaa aggactttgg ggtctgggaa
      301 gtctttacca atatggctca agaagggcat atttacaaat atcatgtcac acgtcaaaat
      361 ggtcatcaac tgatgaagat tgaccctttt gctgtcaggt atgaggctcg tccaggaaca
      421 ggggcaatcg taacagagct tcctgataag aaatggaggg atggactttg gctggcacga
      481 agaaaacgtt ggggctttgc tgaacgtcct gtcaatattt acgaggttca tgctggctct
      541 tggaagagaa atcctgatgg cagtccttat agttttgccc aattgaaaga tgaactcatt
      601 ccttacctag ttgagatgaa ctatactcat attgagttta tgcccttgat gtcccaccca
      661 ctaggtttga gttgggggta ccagcttatg ggttacttcg ctttagagca tgcctatggt
      721 agaccagagg agtttcaaga ttttgtcgag gagtgtcata cccataatat tggggttatt
      781 gtggactggg taccaggtca ctttaccatc aatgatgatg ccttagccta ttatgatggg
      841 acaccgactt ttgaatacca agaccataat aaggctcata accatggttg gggtgccctt
      901 aattttgacc ttggaaaaaa tgaagtccag tccttcttaa tttcttgcat taagcattgg
      961 attgatgtct atcatttgga tggtattcgt gtggatgctg ttagcaacat gctctatttg
     1021 gactatgatg atgctccatg gacacctaat aaagatggcg gaaatctcaa ctatgaaggt
     1081 tattatttcc ttcagcgctt gaatgaggtt attaagttag aatatccaga tgtgatgatg
     1141 attgcagaag aaagttcgtc tgcgaccaat attacgggaa tgaaagagat tggtggtcta
     1201 ggatttgact acaaatggaa catgggctgg atgaatgata tcctccgttt ctacgaagaa
     1261 gatccgatct atcgtaagta tgactttaac ctggtgactt tcagctttat gtatgttttc
     1321 aaggagaatt atctcttgcc attctcgcac gatgaagtgg ttcatggcaa gaagagtatg
     1381 atgcataaga tgtggggaga tcgttacaat caattcgcag gcttgcgcaa tctctatacg
     1441 taccaaattt gtcaccctgg taagaaattg ctcttcatgg gtagcgaata cggtcaattc
     1501 ctagaatgga aatctgaaga acagttggaa tggtctaacc tagaagaccc aatgaatgct
     1561 aagatgaagt atttcacttc tcagctaaac cagttttaca aagatcatcg ctgtctgtgg
     1621 gaaattgata ccagctatga tggtattgaa atcattgatg cggataatcg agaccagagt
     1681 gttctttcct ttattcgtaa gggtaaaaag ggagaaatgt tagtctgtat ctttaatatg
     1741 gtacctgttg agcggaaaga ttttacaatc ggactacccg ttgcaggaat ttacgaagaa
     1801 gtatggaata ctgagttgga agagtgggga ggcgtttgga aagaacataa tcaaactgtt
     1861 caaacgcaag aaggactatg gaaagattat gagcagacct taacctttac cctaccggct
     1921 atgggagcaa gtgtatggaa aatcaaacgt cgcttgaaat ctactaaaac cgtcacaaat
     1981 aaaaaccaaa aaggagtaga aaatgaaaaa tgaaatgtta gctttgattc ttgctggtgg
     2041 gcaaggaact cgtctcgcta aactcactca aagcatcgca aaaccagctg tgcaatttgg
     2101 tgggcgctac cgtatcattg actttgccct atcaaactgt gccaactcag ggattcacaa
     2161 tgttggggtc gttacacagt atcaaccact tgctctcaac aaccatattg ggaatggttc
     2221 aagctgggga ctagacggta ttgattcagg tgtctctatt cttcaacctt attctgcaag
     2281 tgaaggaaat cgttggtttg aggggactag tcacgctatt taccaaaata tcgactatat
     2341 cgacagtgtc aatcctgagt atgtcttgat tttgtctggg gatcacatct acaaaatgga
     2401 ctatgatgat atgctccagt ctcataagga taataatgcc agcttgacag tagcagtttt
     2461 agacgtccct cttaaagaag caagccgttt tggtatcatg aacacagatg ctaacaatcg
     2521 tattgttgaa tttgaagaaa aaccagctca acctaaatct acaaaagctt ctatgggaat
     2581 ctacattttt gattggcaac gccttcgtaa tatgttagtc gctgctgaaa agagcaaggt
     2641 tggcatgtca gactttggta aaaatgtcat tccaaattac cttgagttag gtgaaagtgt
     2701 ttatgcttac gaatttagtg gttattggaa agatgttggt actattgagt cactttggga
     2761 agcgaacatg gagtatattt ctccagaaaa tgccttggat agtcgtaacc gtcaatggaa
     2821 gatttactca agaaacttga tttcaccacc aaacttcctc ggggcaaatg ctcatgtgga
     2881 agactcatta gttgtagacg gatgtttcgt tgatggaact gttaaacatt ctatcctttc
     2941 aacaggcgcg caagttcgcg aaggagcgga agtccttgat tcagttatca tgagtggagc
     3001 tatcattggt caaggagcta agattaaacg tgccattatt ggtgaaggtg cgattatttc
     3061 tgacggtgtc gaaattgatg gaacagatga agtacaagtt gtaggatata atgaagtagt
     3121 gggggtagca acagatgaag attgataaat attctgccat tttaggaaat acagttggtt
     3181 ttcacaatat gtcgacattg acggaccacc gtccagtagc aagtttgcca tttggtggga
     3241 aatatcgttt gattgatttc ccactttcaa gccttgctaa tgcaggtgtt cgtagtgtct
     3301 ttggtatttt ccagcaggat aatatcagct cagtatttga ccatattcgt tcaggacgcg
     3361 agtggggctt atcaaccctt cttagccatt actatctagg aatttacaat acccgtgtag
     3421 aaagtagtac agttggaaaa gaatactacc aacagcttct tacttatttg aaacgttctg
     3481 gctcaaacca aacggttgcc ctcaactgcg atgttcttat taacattgat ttgaaccaag
     3541 ttttccacct acatagtaca acaaaagagc ctatcactgt agtttataaa aaactagcta
     3601 agaaagatat ttcagaagta aatgcaatct tggatgtaga tgaaacagac catgttcttt
     3661 ctcataaact ctttgatagc aagtcaacag ctgaaacgtt caatatgtct acagatatct
     3721 ttgtcgttga tacaccttgg ttgattgaac acttggaaga agaagctaaa aaagaacatc
     3781 cagagaaatt gcgctatgtt ttacgggatt tggctgtaaa agagggagct ttcgcctacg
     3841 agtacacggg ctatctagcc aatattcact ctgttaaatc ttattatcaa gcgaatatcg
     3901 atatgcttga atcacaaaaa ttctattctc ttttctcacc aaaccaaaag atttatacaa
     3961 aggtcaaaaa cgaagagcca acttactatg ctaatacatc taaggtaagc acttctcagt
     4021 ttgcctctgg tagtattatt gaaggtcaag tagctaattc tgttctatca cgtaatattc
     4081 atgtccataa ggatagcttg gttaaagata gcctgctctt ccctcgtgtt gttattggag
     4141 aaggggctca ggtcgaatat gctatcttgg acaaaggggt tgaagttgag cctggtgttg
     4201 tgattcgagg aactgcagaa catccagttg tggttaagaa aggtgctaaa gtaacagagg
     4261 atattcattc atgaaaattt tatttgtagc agcagagggt gcaccctttt caaaaacagg
     4321 tggtttggga gacgtcattg gcgctcttcc aaaatcactg gtaaaagctg ggcacgaagt
     4381 tgcagtgatt ttaccctact atgatatggt agaggctaaa tttggaaatc agattgaaga
     4441 tgtgcttcat tttgaggtga gcgttggttg gcgcagacag tattgtggaa ttaagaaaac
     4501 agtattaaat ggtgtaacct tctactttat tgacaatcaa tattatttct tccgtggtca
     4561 tgtttacggt gattttgatg acggagaacg ctttgccttt ttccaactgg ctgccattga
     4621 ggctatggaa aggattgact ttattcctga tcttctccat gttcatgact accatacagc
     4681 tatgattcct ttcttgttga aggaaaaata ccgttggatt caagcctatg aggacattga
     4741 aacagtttta accattcata atttagaatt ccaaggacaa ttttcagaag gaatgttggg
     4801 tgatttgttt ggagttggct ttgaacgtta cgctgatggc acccttcgat ggaacaactg
     4861 tctgaactgg atgaaggcag gtattctcta tgcgaaccgt gtttcaaccg tttcacctag
     4921 ctatgctcat gaaattatga ctagtcagtt tggatgtaat ttggatcaga ttcttaaaat
     4981 ggagtctggt aaagtatctg gtatcgtgaa tgggattgat gctgatcttt ataatcctca
     5041 gacggatgct cttttagact atcatttcaa tcaggaagat ttgtctggga aagccaaaaa
     5101 taaggcaaaa ttgcaagaaa gagttggctt gcctgttaga gcagacgttc cactggtggg
     5161 aattgtttct cgtttgacac gtcaaaaagg ttttgatgtg gtggtcgaaa gtcttcacca
     5221 tatcttgcaa gaagatgttc agattgttct tttgggaact ggcgatccag cctttgaagg
     5281 agctttctca tggtttgctc agatttaccc agacaagcta tcaacaaata tcacttttga
     5341 tgtcaaactt gctcaggaaa tctacgctgc ttgtgacctc ttcctcatgc caagtcgttt
     5401 tgaaccgtgt ggcttgtctc aaatgatggc tatgcgttat ggaaccttgc cattggtcca
     5461 tgaagttgga ggcttgcgag atacagttcg cgctttcaat ccaatcgaag gaagcggtac
     5521 tggctttagc tttgacaatc tatctcctta ttggttaaat tggactttcc aaacagcatt
     5581 ggacttgtat agaaaccatc cagacatttg gagaaaccta caaaaacaag ctatggagag
     5641 tgacttctca tgggatacag cctgcaagtc ataccttgac ttgtaccata gtttagttaa
     5701 ttaatagata aaatcgtatg atgacttcat acgattttta ggctgtttag agaggagaac
     5761 tgatgtctca agtaaaaggc ttgtgtgttt tggatgtaga tggaacctta atcctagaag
     5821 aagtgattga tcttttaggg agagaggcag gtcatgaggc ggaaatttcg cagattacaa
     5881 gtcgagcaat gcgaggagag ttggtctttg aaagcagttt aagaaaaaga gtgtccttgt
     5941 tggaaggtct tcctattttg gtctttgata acgtcttcaa ctcaattcat ctatcgctaa
     6001 atgtcccaga gttcatctct attctccaaa agaatggcat cctagttggt ctggtgcctg
     6061 gtggatttac accaatagtt ggagagatta gcaaaatccc ttggtattgc ctatttcact
     6121 gccaaccagc ttgaagtcaa agaaggtttt taacaggaaa attagttgga caaattataa
     6181 gtccccaggt caaaaaagaa actctggaaa aatggagaaa gaaactaaaa ctttctaaag
     6241 aaagaacggt ggcaatcggt gatggggtca ataatctatt aatgttgaag tcggcggagt
     6301 taggaatcgc cttttgttcc aaagaaatgc tcaaaaaaga aataccacat catgttgaca
     6361 agagggattt tttagaagtt cttcctttga ttgactgttt agaatgaggg aaaatatgaa
     6421 gattgtaatt gcaccggatt cgtttaagga aagcttgaca gctcaacagg tagctgaagc
     6481 aataaaaaga ggcttccaac aatcgatagc agatgtagaa tatctcctct gccctgttgg
     6541 tgatggggga gaaggtactg tagatgctat ccgacattct cttgacctaa aagaaaaatg
     6601 gatccaagtg acagaccctt ttggacaaaa agaagccatg cgctattttc aaaaagggga
     6661 actggcacta tttgaagtag ctgacttggt tggtcttgga aaaattccgc tagagaaacg
     6721 aaatccactt caaatccaaa cttgtggtat tggagagttg attctccatc tcatttctaa
     6781 agggattaaa gatatttata tcggtgttgg tagcacggcc agtaatgatg gaggactggg
     6841 gattgctgct ggtttaggtt atcaatttta tgatagggat ggaaatgtct tgcctgcttc
     6901 cagtcaatcc ttattaaact tagcttctgt ttcaacagaa aattgctata aaattcctga
     6961 aggtgttcaa attcatattc tagcagatgt cgtgagtccc ttatgtggtc atcaaggtgc
     7021 gacttacact tttggcaatc aaaaaggtct acatccgact atgtttgcag tcgtagatca
     7081 ggcgatccaa gatttttatg aaaaattctc acctgcaaca ttagaaatta aaggagcagg
     7141 agcaggtgga ggccttgctg gtggtttgtg tgcctttgct caggcaagta tcgtgtctgg
     7201 aattgatacc ttgcttggac ttaatcaact ttgataagaa agtttcagat gctgacttgc
     7261 ttgttgttgg agaaggaaga cttgacagtc aaagctttgc tgggaaagcg cctataggtg
     7321 ttgcaaaaag aacccctgtt ggagttcctg ttattgctat ttgcggtagt cttgctgaag
     7381 atttacctcc cctaccattt gaaaatatcc aagctgtctt ttctattttg gagaaaagtg
     7441 aacctttaga agatagtttg aaaaatgcca gtctctatct ggagcgcacg gctgccaata
     7501 ttgggcactt attaaatatg tgcaagattt agctaaacca tttcttccat aaggatgttt
     7561 tggctggttc ttccttttta acttcccaaa gttttggaaa agcaagtcga aggtcttttt
     7621 cttctacttg aactggtgca ttgctatgaa taaccaggcc aaaaggagaa gtaatatgct
     7681 cttcagatac tatggtggct tgactatcag tttcttttgc ttcttttaag tagaaaactt
     7741 gcttatcaaa ttcgatagtt ggtgaaatct tcacaaatag tggctctgct ttttcctgaa
     7801 ggttttctaa aataaataaa aagccttttt ctaactgagg gctatttgct gtgtcaatat
     7861 ctacatatcc aagaactctt tcctcaaaag taccaagata gcgtctttgc tcatccggat
     7921 ttatttttaa cccaccatga gctttttcaa gtaattgttt tgataaatct gtcatgaaaa
     7981 cagtatatca taaaagttag aataaaacag acaaaagaaa gcgattactt tataaagtta
     8041 aggaaaagtt gcacaaagat aacgtttttt cttgaaaaag gaggggtttt aaggtattat
     8101 agaggtgtaa aaaatttaac tcataaggag agtaaaaaat gtcaattatt actgatgttt
     8161 acgctcgcga agtcctagac tcacgcggta acccaacact tgaagtagaa gtttacactg
     8221 aatcaggtgc tttcggacgt ggtatggttc catcaggagc ttctactggt gaacacgaag
     8281 cagttgaact tcgcgacggt gacaaatctc gttacggtgg tcttggtaca caaaaagctg
     8341 ttgacaacgt aaacaacatc attgctgaag ctatcattgg ctacgatgta cgtgatcaac
     8401 aagctattga ccgtgctatg atcgcacttg acggtactcc taacaaaggt aaattgggtg
     8461 cgaatgcaat cctcggtgtg tctatcgctg tagctcgtgc tgctgctgac taccttgaaa
     8521 tcccacttta cagctacctt ggtggattca acactaaagt tcttccaact ccaatgatga
     8581 acatcatcaa cggtggttct cactctgacg ctccaatcgc tttccaagag ttcatgatct
     8641 tgccagttgg tgcgccaaca tttaaagaag cccttcgtta cggtgctgaa atcttccacg
     8701 ctcttaagaa aatccttaaa tcacgtggtt tggaaactgc cgtaggtgac gaaggtggat
     8761 tcgctcctcg tttcgaagga actgaagatg gtgttgaaac tatccttgct gcgattgaag
     8821 ctgctggata tgtaccaggt aaagacgtat ttctcggatt tgactgtgct tcatcagaat
     8881 tctacgataa agaacgtaaa gtttacgact acactaaatt tgaaggcgaa ggtgctgctg
     8941 ttcgtacatc tgcagaacaa atcgactacc ttgaagaatt ggttaacaaa tacccaatca
     9001 tcactattga agatggtatg gatgaaaacg actgggatgg ttggaaagct cttactgaac
     9061 gtcttggtaa gaaagtacaa cttgttggtg acgacttctt cgtaacaaac actgactacc
     9121 ttgcacgtgg tatccaagaa ggtgctgcta actcaatcct tatcaaagtt aaccaaatcg
     9181 gtactcttac tgaaactttt gaagctatcg aaatggctaa agaagctggt tacactgctg
     9241 ttgtatcaca ccgttcaggt gaaactgaag attcaacaat cgctgatatc gcagttgcaa
     9301 ctaacgcagg acaaatcaag actggttcac tttcacgtac agaccgtatc gctaaataca
     9361 accaattgct tcgtatcgaa gaccaacttg gtgaagtagc tgaatatcgt ggattgaaat
     9421 cattctacaa ccttaaaaaa taaaatagtt cagtgaacta ttttatcccg aaccatgaaa
     9481 ttcaaaagtt cggccgttga tttaacaacg tttctagccc ctcggatttt atccgaaggg
     9541 ctatttttgt atttagaggg caaaaaaggg acaaaacttt ttggctcttt gtcaactgta
     9601 gtgggttgaa gtcagctaag ctcgagaaag gacaaaattc gtcctttctt ttttgatgtt
     9661 cagagcgata aaaatccgtt ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg
//
LOCUS       DAVLHM010000063         9293 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLHM010000063 DAVLHM010000000
VERSION     DAVLHM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.063"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..173
                     /locus_tag="VXE45_001905"
     CDS             <1..173
                     /locus_tag="VXE45_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0789890.1"
                     /translation="EELKSLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEWDTI
                     SFDSDFMPFQQS"
     gene            complement(452..1213)
                     /locus_tag="VXE45_001906"
     CDS             complement(452..1213)
                     /locus_tag="VXE45_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0789891.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(1501..2463)
                     /gene="nrdF"
                     /locus_tag="VXE45_001907"
     CDS             complement(1501..2463)
                     /gene="nrdF"
                     /locus_tag="VXE45_001907"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0789892.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(2651..4810)
                     /gene="nrdE"
                     /locus_tag="VXE45_001908"
     CDS             complement(2651..4810)
                     /gene="nrdE"
                     /locus_tag="VXE45_001908"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0789893.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4891..5109)
                     /gene="nrdH"
                     /locus_tag="VXE45_001909"
     CDS             complement(4891..5109)
                     /gene="nrdH"
                     /locus_tag="VXE45_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0789894.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            5460..5723
                     /locus_tag="VXE45_001910"
     CDS             5460..5723
                     /locus_tag="VXE45_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0789895.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5729..7462
                     /gene="ptsP"
                     /locus_tag="VXE45_001911"
     CDS             5729..7462
                     /gene="ptsP"
                     /locus_tag="VXE45_001911"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0789896.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            7717..>9293
                     /locus_tag="VXE45_001912"
     CDS             7717..>9293
                     /locus_tag="VXE45_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0789897.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         2893 a         1721 c         1919 g         2760 t
ORIGIN      
        1 gtgaagaatt gaaaagtctt ggaaaatggt atgtctcgac tggtaaagaa tggatttgtc
       61 attcagatga tgagctggaa gaatttaaaa atctattttt aaattttatc aatcctgaag
      121 aatgggatac tatctccttt gattcagatt ttatgccgtt tcaacaatcg taaccaattt
      181 ctcaaaaaag ttaaatctta tatttagtac tctgtaaaac tcttatctaa tcacgttgct
      241 tatactcaat gaaaatcaaa gagcaacttt aaactaggaa gcgagtcgca gatttctcaa
      301 tgcatagctt tgaggaattg ggcaaaaagt ctttgatata gaaaaaagca tagtatcagg
      361 tgttgaaaca cctgatacta tgctttttat tgtgggaaga tttacttttt ttcttctgaa
      421 attgagttgt tacccaggct ctttcagttt attaaggctt gatgacttta atgtgtttag
      481 atagcttaaa aaggattgaa tcacttagtt tagaatctga aacaatagta tcaagatttg
      541 atatattata aaaagtataa aaatcaaact tattgaactt actatgatct gcgagtaaat
      601 attttttatt agaattattt aaagcgatgc gttgagcctc tccctcttcc tcgctaaaag
      661 tagctagagc tccgttttga ataccattac agctaacgaa agctttagaa aattggagat
      721 tagagagatt ttgtagggtc aatgtgccaa caaaagcacc tgtaatatcg cgataatttc
      781 cacctatcaa aatcaaatct gttaattttc gttcgcttaa aatcagaaaa acaggtagac
      841 tgttggttac gacgcggata ttgtcaatag gcaactcacg cgcaaaaaac tctaatgttg
      901 ttcctggtcc aatgaaaata gtttctcttt cttctactag actgcctgca aaatgggcta
      961 tttcttgttt ttctgccgtt tggagggctt gtttttcaat atttgatcgc tcattagtca
     1021 aaagggagtt ggttcgaagt ttttcagctc caccatgcac acgaatcagc aaatctttat
     1081 cagctaattc ctgtaaatag cgccttgcag tcatatctga aacggctatt tcgtccataa
     1141 tctgtttaac tgttatggtt cctttactat ttactatctc taaaattttg gttaattttt
     1201 cttgtttgag catattatca cctcgtttcc tactactatc ttaccataaa caaactcatc
     1261 attcaaatac aaaaacaaca aaatgaaaca aaaacaaaaa tatcgaagtt tgttttcaaa
     1321 actttcgata tttttgttgg gttattattt tgttgtttct agtttacttt ttgatggtta
     1381 agagtggtgg agaattatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
     1441 gctgtacttg agtacggcaa ggcgaagctg acgtggtttg aatttgattt tcgaagagta
     1501 ttagtccaaa ccgtagttgt agtcatcatc ttgcatggct tcaacttcgc caagaaggta
     1561 accatttccg acttgagaga agaagtcatg gttggaagtt cctgttgaaa taccgttcat
     1621 aacgattggg ttgacatctt cagctgaatc tgggaaaagt ggatcttgtc ccatgttcat
     1681 gagagcttta ttggcattgt agcgaaggaa ggttttaacc tcttcagtcc aaccaacacc
     1741 gtcataaaga ctctctgtgt agccttcttc attttcataa agagtataga gtaggtcgta
     1801 catccattct ttgagttttt cttgctcttc ttcaggtaat tcattgaaac caagttggaa
     1861 tttgtaacca atgtaggttc cgtgaacaga ctcgtcacga ataatcaatt taatgatttc
     1921 tgcaacgttg gcaagtttgt tgttaccgag atagtagagg ggagtgaaga aaccagagta
     1981 gaagaggaag gtttcgagga agacgctggc aactttcttt tcaagtgggc tgccgtttag
     2041 gtagatttcg ttgacaatct cagccttctt ttgtaggtaa ggattggtat tggtccattc
     2101 gaaaatttct tcaatctcag ccttagtatt caaggtagaa aagattgatg agtaagattt
     2161 agcgtggaca gattccataa attggatgtt attgaaaaca gcttcctcat gtggtgtacg
     2221 gatgtctgcg cgaagggctt gaaccccagt ttcagattgc atagtgtcaa gaagggttaa
     2281 accaccaaaa acttttccga ccaagtcttt ctctttgtta gatagctttc tccagtcatc
     2341 caagtcgttt gataagggaa tacgtgtatc gagccaaaat tgctccgtca gtttttccca
     2401 agttgatttg tcgatgacat cttcgatggc attccagtta atggctttgt agtaagtttc
     2461 catttaaaat ctctttctgt gtttagtatt gcgaactcac aattatttct actttaccat
     2521 aattctatag gagtatcgca caaaaagtcg gaagcccgac ttttaaaatg ttacataaat
     2581 tatgttatga catagtagat ttgattttat cagtgctgct tagggaaaaa tagtgtttct
     2641 atgctagaaa ctaaatcaca cagctttcac attggttggc gccgacttct ccaccgtcat
     2701 ctgtaaaggt acggacgtag tagatagact tgattccctt gttaaaggca tagttacgaa
     2761 ggatggacaa gtcacgtgtc gtttgtttat tttccctctt ccattcgtaa aggccttttg
     2821 gaatgtcact acgcatgaag agggtgagtg aaagtccttg atccacgtgt tcagtcgcag
     2881 cagcgtaaac atcgatgact ttacgcatat ccatatcgta ggcagaagtg tagtaaggaa
     2941 tggtttctgt agacaagcca gcagcagggt agtagatttt accaattttc ttttcctgac
     3001 gttcttcaat acgttgcgta atcgggtgga tagaagcaga aacatcgttg atgtagctga
     3061 tagaaccatt tggcgctaca gcaaggcgat tttggtggta aagaccatcc tcttgaacct
     3121 tgtcgcgaag ttcagtccaa tcagcaacac cagggataaa aacatttttg aagagttctt
     3181 taacacggtc tgatgttgga acaaattcac cagttacata cttgtcaaag taacttccgt
     3241 tagcatagtc tgatttttca aagttgtgga aggtaatacc acgttcacgc gcaatattgt
     3301 ttgactctac caaggtccag tagttcataa gcataaagta gatgcttgta aattcaacag
     3361 actcaggtga accatattca atgagttgtt gggcaaggta gctgtgcagt cccatggcac
     3421 cgagaccaaa ggtgtgggct tggctatttc catggtcaat cgttggtaca gctacgatat
     3481 gtgaactatc tgtaacgaaa gtaagggcac gaaccatagc acggatagaa cgaccaaaat
     3541 caggtgaagt catcatgtta accacgttgg ttgaacccag gttacatgaa acatctgttc
     3601 ccatttgaag gaattcttga gcatcgttga tcaagcttgg ttcttgaact tgaagaatct
     3661 cagaacacaa gttactcatg ataatctttc catcgacagg atttgcacgg ttagccgtat
     3721 ctatgttgac tacataagga tagccagact cttgttgcaa tttagagatt tcagtttcca
     3781 aatcccgcgc cttgattttt gtcttgcgaa tatttggatt tgcgaccaat tcatcgtatt
     3841 tttcagtaat gtcgatgtaa ttgaatggca caccgtattc tttttctaca gagtaagggc
     3901 tgaagaggta catttcttca tttttacgag ccaattcgta gaatttatca ggtactacaa
     3961 caccaagtga tagagtcttg acacgtactt tttcatcagc gttttctttc ttagttgaaa
     4021 ggaaagcgat gatatctggg tgaaagacgt tgaggtagac aacaccggca ccttgacgtt
     4081 gccccaattg gttggagtaa gagaagctgt cttcaaaaag cttcataaca ggaacgacac
     4141 ctgaagcagc tccttcatag cctttgatag gtgcaccagc ttcacgaagg ttgctgaggg
     4201 taattcccac accaccacca atacgtgaaa gttgaagagc tgagttgata gaacgtccga
     4261 tagagttcat atcatccgtc acttggatta ggaaacaaga taccaactcc ccacgacgag
     4321 cacgtccagc attcaagaag gaaggagtag caggttggta gcgttggtgg atgatttcat
     4381 tggcaatatc gattgcaaca gcttcattcc catcagcgaa ataaagggcg ttgaagaaga
     4441 cacggtcttc catattttca agatagtatt caccgtcatt agtctttaag gcatattgat
     4501 tgtaaaattt ataagctgcc atgaatgact tgaattggaa gttttggtct ttgataaatt
     4561 gagccaattc ttccaagaac tctggacggt atttcttgat aaaggctgtt tcgatgtagt
     4621 tgtgttcaat gaggtaattg attttgtctt tgattgaatc aaaaaccata gtgtttggaa
     4681 ctacattttc tttaaagaaa gcatccaagg cttccttatc tttatgaagc atgatttgtc
     4741 cattaacagg acggttaatt tcgttattaa gacggaagta agtcacgtct tcaagatgtt
     4801 ttaatcccat aaaatttccc ttatctaatt acaaaagaaa ggcttctaag ttagccctaa
     4861 aagcagtttc ttctggatga tgtactaaga ttatgctaat tgtttcagtt tttctggttg
     4921 gaaacctgaa aagacttcag ttggtgtttg gataacagga gctgcgctaa aaccgagctc
     4981 tttaacttga tcgacgtact caggttgctc atcaagattg atttcacgat aagagacatt
     5041 attactgtcc aagaaacgct tggtcatttt acattggaca caattgtttt tagaataaac
     5101 ggttaccatt gtgtaactcc tcttcaaaat ttaatactat cttagtatat cagaaaataa
     5161 aattttgtca atgatttaaa ctaaatatag tggtgttctt ttgttgtttt tatatataaa
     5221 cacaatatat agtgtttgta ttgtgaaata gcaatgatta tcctataaat tgtttttgaa
     5281 gaaactatat cctgtgtttt gttatctagg atagaagatt ttcagcaagt tatctgaaag
     5341 gaaattgaag gaaaatccag aaaatgcttg aaaaaaatcc tagaagatgg tataatacta
     5401 aattgtaagg gttatcacat ataactcaaa aaaagaaaga acaaaaggag agtcaaacta
     5461 tggcttctaa agatttccac gtagtggcag aaacaggtat tcacgcacgt ccagcaacat
     5521 tgttggtaca aactgctagc aaatttgctt cagatatcac tcttgagtac aaaggtaaat
     5581 cagttaacct taaatcaatt atgggtgtta tgagtcttgg tgttggtcaa ggtgctgacg
     5641 taactatctc agctgaaggt gcagatgcag atgacgctat cgctgcaatc tcagaaacaa
     5701 tggaaaaaga aggattggca taagggaaat gacagaaatg cttaaaggaa tcgcagcatc
     5761 tgacggtgtt gcagttgcaa aagcatatct actcgttcag ccggatttgt catttgagac
     5821 tattacagtc gaagatacaa acgcagaaga agctcgcctt gatgccgctc tacaggcatc
     5881 acaagacgag ctttctgtta ttcgcgagaa agcagtaggt acgctcggtg aagaagcagc
     5941 tcaagttttt gatgctcact taatggttct tgctgaccca gaaatgatca gccaaatcaa
     6001 ggaaactatc cgtgcgaaga aagtgaatgc agaagcaggt ctgaaagaag ttacagatat
     6061 gtttatcact atctttgaag gcatggaaga caacccatac atgcaagaac gcgcagcgga
     6121 tatccgcgac gtgacaaaac gtgtattggc aaaccttctt ggtaaaaaat tgccaaaccc
     6181 agcttctatc aatgaagaag tgattgtgat tgcgcatgac ttgactcctt cagatacagc
     6241 tcaattggac aaaaactttg taaaagcttt tgtaaccaac attggtggac gtacaagcca
     6301 ctcagctatc atggcacgta cacttgaaat tgctgctgta ttaggtacaa acaacatcac
     6361 tgaaatcgtt aaagacggtg acatccttgc tgttaacggg atcactggag aagtgattat
     6421 caacccgaca gatgaacaag cggcagaatt taaagcagct ggtgaagcct atgcgaaaca
     6481 aaaagctgaa tgggcacttt tgaaagatgc tcaaacagtg actgctgacg gtaaacactt
     6541 cgagttggct gccaatattg gtactccaaa agacgttgaa ggtgttaaca acaacggtgc
     6601 agaagctgtt ggactttacc gtacagagtt cttgtacatg gattctcaag acttcccaac
     6661 tgaagatgag cagtatgaag catacaaggc tgttcttgaa ggaatgaacg gtaaacctgt
     6721 tgtcgttcgt acaatggata tcggtggaga taaggaactt ccttacttcg atatgcctca
     6781 cgaaatgaac ccattccttg gattccgtgc tcttcgtatc tctatctctg agactggaga
     6841 tgctatgttc cgcacacaaa tccgtgctct tcttcgtgcg tctgttcacg gtcaattgcg
     6901 tatcatgttc ccaatggttg cgctcttgaa agaattccgt gcagcgaaag cagtctttga
     6961 tgaagaaaaa gcaaaccttc ttgctgaagg tgttgcagtt gcggataaca tccaagttgg
     7021 tatcatgatc gagattcctg cagcggctat gcttgcagac caatttgcta aagaagttga
     7081 cttcttctca attggtacaa acgacttgat ccaatataca atggcagcag accgtatgaa
     7141 cgaacaagtt tcataccttt accaaccata caacccatca atcctacgct tgattaacaa
     7201 tgtgatcaaa gcagctcacg ctgaaggtaa atgggctggt atgtgtggtg agatggctgg
     7261 tgaccaacaa gctgttccac ttcttgtcgg aatgggcttg gatgagttct ctatgtcagc
     7321 aacatctgta cttcgtacac gcagcttgat gaagaaactc gacacagcta agatggaaga
     7381 gtacgcaaac cgtgccctta cagaatgctc aacaatggaa gaagttcttg aacttcaaaa
     7441 agaatacgtt aattttgatt aatcgaaaag tccctgcaac tcagttacag ggactttttt
     7501 tgatatttta aaaagaattt tcaagaaaat ctttcttata aaaagtccaa ccttgaaaaa
     7561 gtagtggtca gaacaaaaaa tacttaaatg gttcataaaa ttcttgacaa gttggagatt
     7621 taggagtaaa ctattaacca gttaagtaat agagaggagt ttctgcaatt tagaaatgaa
     7681 ttgcaactag aaatatcaaa tagaaagaga gtttcgatga aaattaataa gaaatacctt
     7741 gttggttctg cggcagcttt gattttaagt gtttgttctt acgagttggg actgtatcaa
     7801 gctagaacgg ttaaggaaaa taatcgtgtt tcctatatag atggaaaaca agcgacgcaa
     7861 aaaacggaga atttgactcc tgatgaggtt agcaagcgtg aaggaatcaa tgctgagcaa
     7921 atcgtcatca agataacaga ccaaggctat gtcacttcac atggcgacca ctatcattat
     7981 tacaatggta aggttcctta tgatgcgatt ttcagtgaag aattactcat gaaagatcca
     8041 aactataagc taaaagatga ggatattgtt aatgaggtca agggtggata tgttatcaag
     8101 gtagatggaa aatactatgt ttaccttaag gatgctgccc acgcggataa cgtccgtaca
     8161 aaagaggaaa tcaatcgaca aaaacaagaa catagtcaac atcgtgaagg tgggactcca
     8221 agaaacgatg gtgctgttgc cttggcacgt tcgcaaggac gctatactac agatgatggt
     8281 tatatcttta atgcttctga tatcatagag gatactggtg atgcttatat cgttcctcat
     8341 ggagatcatt accattacat tcctaagaat gagttatcag ctagcgagtt agctgctgca
     8401 gaagccttcc tatctggtcg gggaaatctg tcaaattcaa gaacctatcg ccgacaaaat
     8461 agcgataaca cttcaagaac aaactggcta ccttctgtaa gcaatccagg aactacaaat
     8521 actaacacaa gcaacaacag caacactaac agtcaagcaa gtcaaagtaa tgacattgat
     8581 agtctcttga aacagctcta caaactgcct ttgagtcaac gccatgtaga atctgatggc
     8641 cttgttttcg acccagcgca aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat
     8701 ggtaaccatt accactttat cccttatgaa caaatgtctg aattggaaaa acgaattgct
     8761 cgtattattc cccttcgtta tcgttcaaac cattgggtac cagattcaag accagaacaa
     8821 ccaagtccac aatcgactcc ggaacctagt ccaagtctgc aacctgcacc aaatcctcaa
     8881 ccagctccaa gcaatccaat tgatgagaaa ttggtcaaag aagctgttcg aaaagtaggc
     8941 gatggttatg tctttgagga gaatggagtt tctcgttata tcccagccaa ggatctttca
     9001 gcagaaacag cagcaggcat tgatagcaaa ctggccaagc aggaaagttt atcgcataag
     9061 ctaggagcta agaaaactga cctcccatct agtgatagag aattttacaa taagacttat
     9121 gacttactag caagaattca ccaagattta cttgataata aaggtcgaca agttgatttt
     9181 gaggctttgg ataacctgtt ggaacgactc aaggatgtct caagtgataa agtcaagtta
     9241 gtggatgata ttcttgcctt cttagctccg attcgtcatc cagaacgttt agg
//
LOCUS       DAVLHM010000064         8928 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLHM010000064 DAVLHM010000000
VERSION     DAVLHM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8928
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.064"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(298..1146)
                     /gene="dprA"
                     /locus_tag="VXE45_001913"
     CDS             complement(298..1146)
                     /gene="dprA"
                     /locus_tag="VXE45_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0789898.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            complement(1242..1931)
                     /locus_tag="VXE45_001914"
     CDS             complement(1242..1931)
                     /locus_tag="VXE45_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0789899.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1943..2821)
                     /locus_tag="VXE45_001915"
     CDS             complement(1943..2821)
                     /locus_tag="VXE45_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0789900.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2811..3680)
                     /gene="licA"
                     /locus_tag="VXE45_001916"
     CDS             complement(2811..3680)
                     /gene="licA"
                     /locus_tag="VXE45_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0789901.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3697..4719)
                     /locus_tag="VXE45_001917"
     CDS             complement(3697..4719)
                     /locus_tag="VXE45_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0789902.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4724..5431)
                     /locus_tag="VXE45_001918"
     CDS             complement(4724..5431)
                     /locus_tag="VXE45_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0789903.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGNRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5767..7254
                     /gene="tacF"
                     /locus_tag="VXE45_001919"
     CDS             5767..7254
                     /gene="tacF"
                     /locus_tag="VXE45_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0789904.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7264..8067
                     /locus_tag="VXE45_001920"
     CDS             7264..8067
                     /locus_tag="VXE45_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0789905.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8069..8878
                     /locus_tag="VXE45_001921"
     CDS             8069..8878
                     /locus_tag="VXE45_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0789906.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2799 a         1802 c         1515 g         2812 t
ORIGIN      
        1 aaagcgcaaa ctaggaagct agccacaggt tgctcaaagc actgctttga ggttgtagat
       61 aagactgacg aactcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtagt
      121 ttgaagagat tttcgaagag tattatatga gaaaaatcct ctactctact aatccactta
      181 gaaaaaacgc atattagcaa gtgttaaaaa cttgctaata tgcgttttat tatggaaatg
      241 ttgggttcat tttctcttaa aattgatttt ttcttagaat tctagcttag gtcattttta
      301 aaattcaaat tccgcaagaa catcttgccc actggtgagc aattttgctc cttcttgaat
      361 caaatgatgg caaccgtctg atagtccatc taaaatgcta ccaggaatag caaagacatc
      421 gcgtccttct tccattgctc gctcacacgt aatgagacta cctgaacgca tcttagcctc
      481 tgctacaatc acaccacgac aaagtccagc aatgatgcga ttacgggcag gaaaatgaaa
      541 tttcagaggt tgttcgccag gtccatattc acttagaacc agatggtcat tgccgatgta
      601 gtcttgcaag cgtttattgg ctttaggata aaacacatcc agtcctgttc caatcactgc
      661 aatggttttt ccgccattct gaagagctgc catatgagct gctgtgtcaa tgcccttggc
      721 cagaccactg acaataacca gttcattttc caagccttga atgacttttt caactgactt
      781 agctccctgt ttgctacaag cacgactgcc cacgaccgct accttcggga atttcaggag
      841 gtcaagattt cccttgtaaa ataaaagtac aggcgcatca tatatttcac tcaaatccca
      901 aggataacag tcatctaaaa tagagaaaga tggaaatttt tgaaactctt tcgacaaatg
      961 cgcatcgtct atctgaaaat aacgttccat aaaaacggct ggattacggc aacctgatat
     1021 atctgcaata tcacccaaca aaagctcctg atcaacattt tcaccgtatt ctagcacttt
     1081 caaaatctgt tgattggtca aacctgattt ttttaactta tagatttcat agtttgtgat
     1141 tttcataaat aactccattt ctttttctac tcatctatct attcgtaaaa gttcgtaaaa
     1201 aatcaaaaaa catccgacta ttttgtcaga tgttggaatc tttaattttc gtttttaaga
     1261 atttcttcta atttacgata gtcttggaca ctatcgatct cataaatgct attgccttct
     1321 aattcttcaa catagacatc tagctctttg atattatcct taaccatatt gtcccaatag
     1381 agatcaacaa attcaccact tgcataagcc ttgtcgataa agctgacaat cttttctgca
     1441 gttggagcat cccagaagga tacaccacta aggatgcgac ctgccttgct atcaacaata
     1501 atgtcttgaa ccttgtagtc atctccatag accaagaacc attcgttggt acaatcttca
     1561 cgataaacac taaaataagt cgaacgtgtc aaatcattgc ggaacatatt tttaaagaga
     1621 taattgtcag catcaataac atagctgttg gccaattctt cttttacaag atagagagag
     1681 taaaagttat tgtagtcagc gtatttatca ttgaaaacga ggcgaacacc gtatttttct
     1741 tttaagtaat cgaattgttc tttaagataa ccaacaatga tgatgatgtc attgattcct
     1801 ttttctttga gaaactcaat ttggtattca atcaaaggtt tttgattaac ctgaaccaag
     1861 gctttagggg tattttcagt cataggacgc aagcgagttc ccaatcccgc tgctaagata
     1921 atggctttca cacgaatctc ctttattctt taataataat ataaactcca gcaatgacga
     1981 caagtgacgt cataatggtc agcatatcta gcggtgcacc caaaaaaaca actgcaaaca
     2041 agaccgtcca tactacatag ctcacgttca agcctgtagc cttggctggt tgcaagcgat
     2101 tgatagcgat ataataagcc aagtaggaaa tcatatcaaa ggctgcaaaa acaatcatga
     2161 gacctagcaa ttgtccattg gctactgcag taaatgactg atgagagaag agcacaatca
     2221 caagatagga caagaacgaa gtcacttgac ggattaagag ggcttcgatt tcactcagtt
     2281 cactttccat agcaaaggag ctaagaacac tctcacttcc ccatgcaata gcacaaacca
     2341 aagcacagag aatcccaatg tagaaggaat taacctgttc aaccttatag gtctgggcaa
     2401 taatccctcc aataatcaag acaatcccaa atacagtatt tttcgaaatc ttgtgcttca
     2461 aaaagaagaa agccaataga actgaaatcg cagggtaaat agccgataca gatgaagcta
     2521 aagaacttcc gatatactta actgcataaa gattggcctg cataccgata gggcctgcta
     2581 gcaaggctcc gatgataaca ctgacattgc gaatatttaa gaaaattgag aggcgaactt
     2641 tcccttcttt taccaagaga aaagctagta agataaagat gctcaaaaaa tcatgagctg
     2701 cagccaccac aaagggtgac aaatctgtaa aaatcgaaaa gatataagca ctaaccgtta
     2761 gacccaagcc ccagaaaata cctgagagaa ggccaaaagg aactccgttt ttacttttca
     2821 tctgaacctc cataagaagc caaaccttta acagctcttt ggtaacgatt cacaccatag
     2881 tcaccaaaat cttcaccttg ctcttcctta tagacagtcc atagactcca aatagtatct
     2941 tgtaaaattt tataaatagc aatcttttca tgagaaaccg gtgtttggtc actctcatag
     3001 tgagataaga aagtttcttc ctcttgggaa gtgaattcag actctaaaaa gagggcagcc
     3061 aaatcccaca ttggatcatt cattgatgaa tattcccagt caatcaaata aagtcgtcct
     3121 tgaggtgatt cgataaagtt ttcaggcacc aaatcgatat gacaagattt tctgtcaaca
     3181 cctaagtcag ccagtctttt ctctaaggag aagactgcat ttctaacaga ttcatagttg
     3241 gcataaggaa tttgttcttc aatcaaggat tcgtattttt tgatttcttc aaaaggagca
     3301 aattctcctc ttaattcctt agcagacgta tgaatagttt gtaatattgg agcaattttg
     3361 tcgaacttgg tcttgattga cgttgaatca agcgtaatcg cagattcgat atactcattt
     3421 actttgatac cagcttcaat atcaaaaaga taatttttta catctaagcc taaatccttt
     3481 agtagttcaa gattgtactt ttcatcttgt cgattgataa gcttttctgt ccctttacca
     3541 aagaatttaa caatgtattg cttatttgtt gttttggcca aatagttttg attggtcatt
     3601 ccacccagtt gttcaacact gaggacttcc tcttcttgac taagtaagga agaaattttt
     3661 tctttaatga ttttctccac aattaacctc cagtacttat acttcccact taaacactgt
     3721 tttaaaggct gtgtttaaat cggttgcaaa gacacgatga atatctttaa tttctcttac
     3781 aggttcttct agataaagga tatttttaag acgattggca aatttcttga cttccatcat
     3841 ttggatagca tttttaaaat caatgcgacc agaacgagat gacccaacca aaatcaagcc
     3901 cttttctaag gcatcgcgag tattgagatt gactttatat tcgctaactc ccatcatgag
     3961 aatcgttccc tgaggacgaa tgtagcgaat caagtcatta atagctggtc cagtaccatc
     4021 accaccacaa cattcaaaag catggtcaaa ggccaactct tcaggaatat tatccgtaat
     4081 atagcattct ttggcaaatg agaagagttc caacttttcc caatgacgac caataaccac
     4141 aatctctgat tctggcaaag tatagttgat aatattggca accacaaaag ctaaacttcc
     4201 atctccaata acggcgatcc gctcccgctt gctatgagca agagtcaata gacgattcat
     4261 agcgtgcatg cccacactga caaactctgt aatggctgca accgtatctt caatagcatc
     4321 ataagccacc acacgatctt tagggagaga aacaaactct ctcataaagc catcaaatcc
     4381 actagacaag aaatgggtcc ctgtcatgta gttttcatag aattcttcat cactctgcat
     4441 aggagactga ttgggaatca tgacaacttt ttgaccaacc tcgtaggttc cggtcgggtc
     4501 agaaatgacg gttccacatg actcgtgaat cattgccatt ggaagctttt tattcaaaat
     4561 cttgggatca cgttttccct gatagtaacg ctgatccgca tgacagacag ccatgtagtt
     4621 gggacggata aggatatgat tctcttggtc aatagcctct tcctgatatt tgacattgat
     4681 aaacttaggc ttagttagtt gataaatttg attaatcatt ttactagtct ttctcaatca
     4741 tactttttgc aatcttcaaa tctgttacgg ttgtaatctt cagatttgag tattcacctt
     4801 tggccaaggc cacatctttt cctttgatca caaagatttt acatgcatct gtcaagattt
     4861 ccttctcttc atcagaaaga gatccataaa ggtccatgaa gtccttgcaa cggaatgttt
     4921 gaggtgtttg tccttgataa aggtgagcac gatttggaat atctgtaata aattgaccat
     4981 tggtactttc aacgatagta tcaaccgctt ctaccactgt gtccactgcg tcatgatttt
     5041 gggcaagttg gatattgtcc tgaatcatgc gaagtgtaat aaatggacga acagaatcgt
     5101 gggtaacaac gatatcctct ggagtaagcg gacgataagc atcaatggct tcaatgattt
     5161 tcttaatact tgtattgcgg tcagcaccac cctttgtaat gatgatacgt tccttataaa
     5221 gaggaagata tttatctaca agatcttctg catgagaaac ccagtctcca tgaacaccaa
     5281 ctacaatttt ttcaatactt ggctccaaga caaatttttc aattgtatga atcaaaatag
     5341 gtcgattacc tagctctaaa aattgttttg gcaagttact gatccccatg cgtgtgccag
     5401 ttccaccggc aagaattcct gcataaatca tctattttct cctttgtctt actaaaaaaa
     5461 cttattctct ctattatacc acaatctagt cctatcataa aagaaatact ggtcctcccc
     5521 ttctagaata ggagaattat gcagttctat tattcaaaga aactagtcca tttctagtaa
     5581 tgactaggaa ttctgtagca attactaata aatggctgcg aaattttaga gtccttcaga
     5641 ataatatact ttccttaaag aaaacttaaa acttaagatt tgaaacttca aagtgattac
     5701 ttgacttact gcccttcatt tcttattagc taactttatg atataatgaa aaacgaggta
     5761 aattgaatga aaagtataaa attaaatgct ctatcttaca tgggaattcg tgtcttgaat
     5821 attatttttc ccatcctaac tggaacctat gtcgcgcgtg tcttggaccg aactgactat
     5881 ggttacttca actcagtcga cactattttg tcatttttct tgccctttgc aacttatggt
     5941 gtctataact acggtttaag ggctatcagt aatgtcaagg ataacaaaaa agatcttaac
     6001 agaacctttt ctagtctttt ttatttgtgc atcgcttgta cgattttgac cactgctgtc
     6061 tatatcctag cctatcctct cttctttatt gataatccaa tcgtcaaaaa ggtctacctt
     6121 gttatgggga ttcaactcat tgcccagatt ttttcaatcg aatgggtcaa tgaagctctg
     6181 gaaaattaca gttttctctt ttacaaaact gccttcatcc gtatcctgat gctggtctct
     6241 attttcttat ttgttaaaaa tgaacacgat attgttgtct atacacttgt gatgagttta
     6301 tcgacgctga ttaactacct gattagttat ttttggatta aaagagacat caaacttgtt
     6361 aagattcacc taagtgattt taaaccactc tttctccctc tgacagccat gttagtcttt
     6421 gccaatgcca atatgctctt cactttttta gatcgcctct tcctcgttaa aacagggatt
     6481 gatgtcaacg ttagttacta taccatagct cagcgaattg tgaccgttat agctggggtt
     6541 gtaacaggtg caattggagt gagtgtgcct cgtctcagtt actatctggg gaaaggagac
     6601 aaagaagcct atgtttctct ggttaataga ggtagtcgaa tctttaactt ctttatcatt
     6661 ccactgagtt ttggactcat ggttttagga ccaaatgcca tcctacttta cggtagtgaa
     6721 aaatatatcg gaggcggcat cttgacctct ctcttcgctt ttcgtacgat tatcctggcc
     6781 ttagatacca ttcttggttc ccaaattctc tttaccaatg gctatgaaaa acgtatcaca
     6841 gtctatacag tctttgctgg gctactcaat ttgggcttga atagtctcct ctttttcaac
     6901 catatcgtgg ttcctgaata ctacttactg acaactatgt tatcagagac ttctctactt
     6961 gttttctata ttattttcat ccatagaaaa caactcatcc acttgggaca tatctttagc
     7021 tatactgttc gatactctct cttttcactt tcctttgtag caatttattt cctgattaat
     7081 ttcgtgtatc ctgtggatat ggtcattaat ttgccatttt taattaatac tggtttgatt
     7141 gtcttgctat cagctatctc ttatattagt ctacttgtct tcacaaaaga tagcattttc
     7201 tatgaatttt taaaccatgt cctagcctta aaaaataaat tcaaaaaatc ataggagttt
     7261 aaaatgaaac aactaaccat tgaagatgcc aaacaaattg aattagaaat tttggattat
     7321 attgatactc tctgtaaaaa gcacaatatc aactatatta ttaactacgg tactctgatt
     7381 ggggcggttc gacatgaggg ctttatccct tgggacgacg atattgattt atccatgcct
     7441 agagaagact accaacgatt tattaacatt tttcaaaagg aaaaaagcaa gtataagctc
     7501 ctatccttag aaactgataa gaactacttt aacaacttta tcaagataac cgacagtacg
     7561 actaaaatta ttgatactcg aaatacaaaa acctatgagt ctggtatctt tatcgatatt
     7621 ttccctatag atcgctttga tgatcctaag gtcattgata cttgttataa actggaaagc
     7681 ttcaaactgc tgtctttcag taaacataaa aatattgtct ataaggatag ccttttaaaa
     7741 gattggatac gaacagcctt ttggttgctc cttcgaccgg tttctcctcg ttattttgca
     7801 aataaaatcg agaaagaaat tcaaaaatat agtcgtgaaa atgggcagta tatggctttt
     7861 attccttcaa aatttaagga aaaggaagtc ttcccaagtg gtacctttga taaaacaatc
     7921 gatttaccct ttgagaattt aagccttcct gcacctgaaa aatttgatac tattttgaca
     7981 caattttatg gagattatat gaccctacca ccagaagaaa aacgcttcta cagtcatgaa
     8041 tttcacgctt ataaattgga ggattaggat gcaatattta gaaaaaaaag aaattaaaga
     8101 aattcaacta gccctgctgg actatattga tgagacttgt aagaaacatg atattcctta
     8161 ttttctcagt tatggaacca tgcttggagc catccgccac aaaggtatga ttccttggga
     8221 tgatgatatt gatatttccc tttatcgtga ggattatgag cgtttactga agattattga
     8281 agaagaaaat caccctcgct acaaggttct ttcctacgat acatcttctt ggtacttcca
     8341 taatttcgca tcgattttgg acacttctac tgttatagaa gaccatgtta agtacaagcg
     8401 tcatgatacc agccttttca tcgatgtctt cccaattgat cgatttacag acttgagcat
     8461 tgtcgacaag agctataagt atgtggccct tcgtcaacta gcttatatca aaaaatcacg
     8521 agcagttcac ggtgatagca aactaaaaga ttttcttaga ttatgtagct ggtacgctct
     8581 ccgatttgtc aatcctcgct acttttacaa gaaaattgat caactagtca aaaatgctgt
     8641 aaccaacact cctcaatatg aaggaggagt tgggatcggt aaggaaggga tgaaagaaat
     8701 cttcccagtt gataccttta aagaactgat tttaactgag tttgagggcc gtatgttgcc
     8761 tgttcccaaa aaatatgacc aatttttaac ccagatgtat ggcgattata tgacaccacc
     8821 atcaaaagaa atgcaagagt ggtatagtca tagcattaaa gcttatcgca aaaactgatt
     8881 gagggggatt atacaaacta ctaagataga ggttattcaa aaacataa
//
LOCUS       DAVLHM010000065         8286 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLHM010000065 DAVLHM010000000
VERSION     DAVLHM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.065"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            146..793
                     /locus_tag="VXE45_001922"
     CDS             146..793
                     /locus_tag="VXE45_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0789907.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            924..1337
                     /locus_tag="VXE45_001923"
     CDS             924..1337
                     /locus_tag="VXE45_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789908.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            1356..1541
                     /locus_tag="VXE45_001924"
     CDS             1356..1541
                     /locus_tag="VXE45_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789909.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(1808..2251)
                     /locus_tag="VXE45_001925"
     CDS             complement(1808..2251)
                     /locus_tag="VXE45_001925"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0789910.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(2281..4503)
                     /locus_tag="VXE45_001926"
     CDS             complement(2281..4503)
                     /locus_tag="VXE45_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0789911.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5519..6148
                     /locus_tag="VXE45_001927"
     CDS             5519..6148
                     /locus_tag="VXE45_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0789912.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VXE45_001928"
     CDS             complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VXE45_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0789913.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         2249 a         1903 c         1590 g         2544 t
ORIGIN      
        1 ttattttcag ggttttattt ctatcatttt attttacttt catttggtgg gagaatattt
       61 gaaaaaaaga aaggtagttt aacctatgaa aaaatcacta aaaatttttg ctacatctaa
      121 atagtttgac ctcttcgggg ttgctttggt cgttgggatt gcgattgcat ctggttacct
      181 caactcacac ctcgataaat ttgtagactg gggatcatgg acagctcttg taccctttgg
      241 attgatttcc gtaaccaacg ttgggatttc catgttgtcc actcgtttca cggggaaatt
      301 aagcaaatgg ggaaattact ttggtattgt taataccatt ttgtccggtg ctattgatta
      361 tatccttgga aataaggcgg ccatcattac ctatcccgtc accttcctca tttatacctt
      421 tgctataaag aagtgggaag cttcgcaaga aggcagaccc aaccaaatga gccaaaaaca
      481 ggtaaaattg gcggccatca tcatttccat catcgccttc ctctttgcct ttgtgaccaa
      541 ctatatcgga tatgggggca agatgaatct ccttgcctac gtaacaacta ttgcctttgc
      601 actgtccctc attgccaatg ctttgaatgc attaaaacta acaactcagt ggggcttttg
      661 gttgatttac aatttcgttc agctgacaaa agctggtatt caaggaaact tcgccaatat
      721 cggtaaatac atcttttata tcctcaatgc aatcggagct ttatttgtct ggaatgatga
      781 agaagttaga taatagaagg aaactcaaat aaagaatact agccaactta agagaatctc
      841 ccttctgcta tttttatcat tttagttgta actcccattc ttttggagta gaatgaagtt
      901 agataaaaga gggaggtctt gtcatgaaaa aactctatag aatccatttt atagcaattg
      961 cagttattga tttgctacta tttgcatttt ttatcactag actcgagaca tcttttgagt
     1021 ggctcttgct ctctggttta attttcttcc ttgctcaagg actcctgcta tttctcttgg
     1081 tcgtccgact caaacatcaa ttcgctgaga tttatcctca aatcaataaa aagattcgct
     1141 tctactattt aggggttctc accattgatt ttctattttt tgttctctta gccttcatta
     1201 gttctcagcg tttttcatct cttatgccaa tcatcactgc ttgccattct actttttatt
     1261 atatgacagc tgactaccta agagaaaact atccagactt ttacgacaaa cacatctctt
     1321 tatgggagtg tctctaagga aaaggaggtt ttagcatgaa aaaaatcatc ttcatcaaaa
     1381 ccattcaact ccttgtcatt gatggaatca tgctggcatt tttgacattt aaaagggggc
     1441 ttacttggga ctggattttg atttatagcg gttggctcat tttctttcat cctgtgctat
     1501 tgacctatct ttcaaaccaa ctttgtgacc actttagtta actctattcc cagattagac
     1561 cgagattctg gcgttttgct ttacaaattc tcctatggga tagcctgatg attctctcct
     1621 tggtgtcttt aagtgatatt ccacttttcc ttcagggaac tctcctcatc ctaggacatc
     1681 tcatcccttc ctatcgcatc tgccaaagcc tgaaaagaga cttcccccaa gcatatcaag
     1741 aaccgatttc tttttggagt attttatgat agatgagaaa gaccaagccg actgggcttg
     1801 gtctttctta tctcttttta gtatctagga taatggtaac aggtccatta ttaaccagct
     1861 caacctgcat atctgctcca aagatgcctg tctgaacggg cacttcttgc gctaattttt
     1921 gattgaaagc atcatagaag tctgatgcca tatcaggttt agctgcccct gtaaaggctg
     1981 gacgattgcc tctcttagta tccgcaaaga gggtaaactg agaaatagag aggatttctc
     2041 cttcaatatc tttgacagac aggttcatct tgccttctgc gtctgaaaaa atccgcatat
     2101 tgaccagttt tctcacagca tagtccaaat cttcctcttg gtcctctggt ccaacaccaa
     2161 ccagcaataa aagtccctga ttgatttttc cctgaatctg gccttctata ctcacttggg
     2221 cttttttaac ccgttggata atgattttca taatagcctt tctagtaaga gctaggacaa
     2281 ctagccgttg gtccgtttga cagagtaaac ttctggcaca ctcttaattt tatcgacaac
     2341 cgtggtcagt gtagagaggt tggcaatacc gaaggacaca tggatattag caaacttcat
     2401 atccttggtt ggttgggcat tgaccgttga aatattcttg gttgtatttg aaagaacttg
     2461 cagtacatcg ttcaacagtc ctgtacggtt gagaccgtag atatcgatat gggccatata
     2521 ctccttattt gagctagggt actggtcttc ccattccaca tcaaggagac gttgctcgta
     2581 gttttcttgg gcacgcaggt tcatacagtc cacacggtga atagccacac cacgaccctt
     2641 ggtaatgtag ccaacaatat cgtcaccagg cacggggtta caacacttag caatccgcac
     2701 taggagacca gaagcacctt caataaccac tcccccctca tgcttgacct tgagggtttc
     2761 tttattttca accttgacct cgccaccttt gacaagctcc tctgcctcag ctttggcctt
     2821 ggcacgctct tcctcacggc gttccttttc agtcagacgg ttaaagacgg taatcgcacc
     2881 gatttcccca aaaccaatgg ccgcaaagag ggagtcttct gtcttgtaac tggtcttttg
     2941 cagaacttga tccatgtggc gcttgtccat aaatttattt gccacatagc cattttcttg
     3001 gaactgagcc atcagcatct cacgaccctt gttgacagac aattccttat cttggttttt
     3061 aaagaactgg cgaatcttat tgcgcgcctt gctagtcttg accatattga gccagtcacg
     3121 gctaggtcca aaggagttcg ggttggcgat aatttcaacc tgatcccctg tctttaactt
     3181 ggttgtcagt ggaaccatgc ggccattgac cttggcacca gttgcttttt caccgacctt
     3241 ggtatggatt tcgtaggcaa aatcaatcgg tcctgaatct ttgggaaggg aacggacagc
     3301 tccatctggg gtaaaaacgt aaatctcctc agccaaatag ttttccttaa cagagtccac
     3361 aaattcctta gcatcatcag cctggtcttg gagctccatc atctccttga tccagttcat
     3421 tccaatagct gattccttgc tgttaacttg cccctttata cctttcttat aagcccagtg
     3481 agccgcaacc ccgtactcag ccacctcgtg catttccttg gttcgaatct ggaattcaat
     3541 cggccctttt ggtccataaa cagtcgtatg gatagactga taaccattgg ccttgcggtt
     3601 ggcgatatag tctttgaagc gacctggcat cggtttccaa aattcatgca cgtaaccaag
     3661 catggcataa acatcacttt gggtatctaa aatacaacga atagcaatca gatcatagat
     3721 ttcctcaaac cgttttctct tgtcctgcat tttgcggaaa attgagtaaa tatgcttggg
     3781 acgaccataa atcttccctt tcaagtgacg ttctgtcgta tactcctcta attttgtgac
     3841 tacctcatcc accaaggcct cacgctccct gcgcttttcc ttcatcatat gggtaatctt
     3901 gtaaaactcc gttggattga gataacggaa agacaagtct tctaattccc atttgacact
     3961 ggaaatcccc aaacgatggg caagcggggc atagatttcc atggtttctt tggaaatacg
     4021 ctcctgcttg tcttttcgaa gatgtttcag ggtccgcata ttgtgcaagc ggtcagacag
     4081 tttgaccaaa ataacgcgga tgtcctcaga catggccatg agcatcttgc gatgattttc
     4141 cgctaattgc tcctcgatcg atttgtactc gaccttgcca agcttggtaa ctccgtcaac
     4201 aatcacccgc acatcaggac caaactctct ttccaaatcg tccaaggtcg catctgtatc
     4261 ttccaccaca tcatgcaaga atccacaagc tactgttaca gcatccagct ttagcttagc
     4321 taaaatacct gccacttgga tagggtgaat gatataaggc tcgcctgatt tgcgatattg
     4381 accactgtgg cattcaacag catagaccaa ggccttatgg acaaaatgaa catcctcttc
     4441 cgttaaatat tctttggtta aagcgacaac ttcttcgcct gttaaattca cttctttcgg
     4501 catctctact ctccaattct tcctaccatt ttatcacttt tttaagaata tgaaaactag
     4561 attggaacag aataagaaaa aaataattca aaattgcttg ataattctga attattggcc
     4621 cataatatac tacgaagtta gattttaaac ttaggtgata gaaggagaga tagaagaacg
     4681 gaaaccatat tgtaacccaa agactttctg atttccccaa ttccattgaa gatacgaaag
     4741 ataaacggtg gaactcgtat cacatacact ggtaccttga ctggattttg gaattaatac
     4801 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa gcactgcttt
     4861 gaggttgtag ataagactga caaagtcagt cacatatata cggcaaggcg acgttgacgc
     4921 ggtttgaaga gattgttgac gcggtttgaa gagatttttg aagagtataa aaatcctcaa
     4981 gatactttct tctatccttt agtttataag gagaatacct atgaaaaaaa ctgctatttc
     5041 tatctttgct ctcctaatgt taggagtttg ctgcctgttc ctattcagcc agcaaagcta
     5101 taaaaaactc gttcaatact atgctaacga ccagaacctg cccagtagga taacttatag
     5161 tgaatatagc gacaaatgat aagccaacta cggtagcact ctaaacatca cgtctatcaa
     5221 acaagctaat gacggagttt atgcaaccta tgaagggcaa ttgacacctt tccaatattg
     5281 ataaattgat aaccagcctg tcttcatcta gtcatgctgg tttttaagtt cattttaaat
     5341 ccttacctat tctccctaac tgtgctatac ttaatttata ctcaatgaaa atcaaagagc
     5401 aaactagaaa gctagccgca ggctgttcaa agcactgctt tgaggttgca gataaagttg
     5461 acgcggtttg aagagatttt cgaagagtat tagtacattc tttgagattg gagctagtat
     5521 gaaaatccat aaaaccgtga atcctgttgc ctatgaaaat acctattatc tagaaggcga
     5581 aaagcacctc atcgtcgtcg atcctggtag tcattgggaa gccattcgtc agacaatcga
     5641 gaagatcaac aaaccgatct gtgctattct cttgacccac gcccattatg accatatcat
     5701 gagtctggac ttggttcgcg agacgtttgg caatcctcct gtctatatcg cagagagcga
     5761 agccagctgg ctctacactc ctgtcgataa tctctccggt ctccctcgcc acgatgatat
     5821 ggcagatgtg gtcacaaaac ctgcagaaca cacctttgtc tttcacgaag aataccaact
     5881 agaggaattt cgttttaagg ttctaccgac cccagggcac tctatcggtg gtgtttccct
     5941 agtctttcct gatgctcacc tagtcttgac gggagatgct ctattccgcg aaactatcgg
     6001 acggaccgac cttccgactg gtagcatgga gcaactcctt catagtatcc agacccaact
     6061 cttcacccta ccaaactacg atgtctatcc aggacatggt ccagctacta ctatcgctca
     6121 cgaaaaggcc ttcaatccct ttttctagca agatgatgac aatcgaaatt taagtaaact
     6181 atccagcaaa tctttctatt acaaaaggca tcctatcaag gttttcacac gtgattggat
     6241 gccttttttc tgatgactag attttttgta ttaccaaata atcacgcgct cctctggtga
     6301 acgccacatt ccgtctcctt ctttgacatc ataggttgta aagaaatcgt cgaagtttgg
     6361 tacttgcaca ttgacacgga gtttggctgg tgcgtgcaca tcgacgctag ccaaaagttt
     6421 cataaattct ggtcgacctt tcatgcgcca gatgcgaccg aagttgtaga agaactcttc
     6481 tgctgagaag tctgcttctc tcttagctgc ttcaagcgct gctgcgattc ctcccaagtc
     6541 agccacgttt tctgatacag tcaatttacc gttaatggtt gctccataag aatcctgtcc
     6601 atcaaattgg tcaatgactt tttgtgtttt ctccttgaag gcagcatagt cgctctctgt
     6661 ccaccaatcc ttgaggctac cattttcgtc aaaggaagcc ccgttagtat caaaggcgtg
     6721 ggaaatttca tgggcaatca ctgccccaat accaccgtag ttagcagaag atgactgatg
     6781 caagtcatag aaaggcgcct gtaaaatggc cgctggaaag acaatcaggt tcttctgagg
     6841 attgtagtag gcattgacca tatgagcagg catgccccat tccttatagt ctacaggctg
     6901 gttccactta ctccaactgt gcttgatttc cacacgcgca aaggctagag cattctcaaa
     6961 aagactggca gtttcattca ctaccttatc cttgtaacgt gcaggcaatt cttctggata
     7021 gccaatataa ggtttgatca cattgagctt cacgatagcc tgtttacagg tttctggagt
     7081 gagccagtca ttcttaagca gacgctcctt atagacatca atcatggttg ccactttttt
     7141 ctccacatcc gccttggctt ctggagagaa cttctcacgg gcgtaccaaa gacccagggc
     7201 ttgcttgaaa ggttcttgtg ctagatgata agctgctttg accttatctt ttgcctctgg
     7261 aactccagaa agggcacggc tgtaggcacc agacaaaaca cggatatcct ctgttaaata
     7321 gctggttgaa agattgacaa cactcaaaat caaggttgct ttaaggagag accaggcttc
     7381 ctcactgtag aattgctctg ctgcttgcca gaaacgttcc tcgtctacaa taaccttgtc
     7441 tggtaattgc ccaataactg ctttgaagaa gtcatccaaa ggtagggcag gcgcgaattt
     7501 cttaaaatct tcgtaagaat atggatgata gagtttagca tattctgaac tttcttcatt
     7561 agagagcacc actgccgcaa ctcggcggtc caattcaagt cttttttcta gcaagtcttc
     7621 aatttcttca tcagagaaat cataagcctt gaggagattt gcgctgcttt ctttccaaag
     7681 agtcaagagc tcttcgcgct gaggatgttc ttctgcatag taggtcgtat ctggcaagat
     7741 tgtgcttgga gcgctagccc atagaacatt gattctagca tccataaagt ctggcgatac
     7801 accaaaagga aggaagtttg gttttcctgc aagctcaaac tctgctagtt tagctgtaaa
     7861 atccgcaaaa gtttccaatt cttggaattc tttaaggagt ggtaagacag gtgtgatacc
     7921 gtcagcttct ctcttgtcaa aatcacgaac taggcggtgg tatttgacaa agttttccaa
     7981 gatagcatcc tcaggcactt cttcacctgc taaccacttg tctgttgtcg ccagcatcag
     8041 gtcttcaatt tcctggtcta aatcaacaaa acctccagtt tgagacttat ctgctgggat
     8101 ttcagctgtc tgttgccatt ctccattgat agcatcataa aaatcatctt gataacgtgt
     8161 catcttgttc tcgctttcat ttgtatttgc atttatctta acaaaaatca ctagggaatg
     8221 caattaataa ccatttaact attatttttt agctattata aaaaatcttt ccatgataaa
     8281 acgcat
//
LOCUS       DAVLHM010000066         7929 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLHM010000066 DAVLHM010000000
VERSION     DAVLHM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.066"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(616..1608)
                     /locus_tag="VXE45_001929"
     CDS             complement(616..1608)
                     /locus_tag="VXE45_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789914.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1768..3522
                     /locus_tag="VXE45_001930"
     CDS             1768..3522
                     /locus_tag="VXE45_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789915.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3506..5227
                     /locus_tag="VXE45_001931"
     CDS             3506..5227
                     /locus_tag="VXE45_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789916.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDVK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            5238..5822
                     /locus_tag="VXE45_001932"
     CDS             5238..5822
                     /locus_tag="VXE45_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0789917.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            5822..6517
                     /locus_tag="VXE45_001933"
     CDS             5822..6517
                     /locus_tag="VXE45_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0789918.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            6505..7869
                     /locus_tag="VXE45_001934"
     CDS             6505..7869
                     /locus_tag="VXE45_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789919.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINELAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         2847 a         1078 c         1375 g         2629 t
ORIGIN      
        1 catatgattc tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt
       61 ttttctacac aaaataggct ccataatatc tatagtggat ttacccacta caaatattat
      121 agaacccaaa aatgctctga aacactgatt tcaaggcatt ttttgttagt ttaaaattac
      181 tcccattctt cttttccaaa catacaatat atccaaaacc attcaaaata ctagattcta
      241 ttttttataa tatcactaaa tccacctaat tataggacgt tttcagattt ttagtcccgt
      301 cccagtccca gtaccggaga aatattgttt taatataata tctctttttg tcttctaagc
      361 tcttaaaagc aaaagaacaa gtaaagagtc aagacaagga taaaaagtcc atattagggc
      421 aaataaaaag ctttaagaca gatgacaaat ctaagtcaaa taagaaagac catagcaaag
      481 gtgcagagag ataaatattg gcggtcttcg gactgccttt atttttttat ccatttttca
      541 aatcaaattt attcagacta tatatgcaca tatacactta aattcatata aaaacatggc
      601 ttgtaaaaaa ttactttaat cacaataatc gcatttaaaa ttgtgatgtt tgcaagctaa
      661 attacggact tcacttggaa gttttccctt gtatctttta taatagatag aaaatttgct
      721 ggcagatgaa tatccaacag attctgctat ctcttttata ggtagttcag tgtttaaaag
      781 aagagtttca gctacattca ttctttttct ttgagtgtac tctgtaatgc tttgacaata
      841 tttttcctta aataaatttt ttaatttagt accactcatt ttagatattt tttcaagcgt
      901 gccttgattt acattcgttg caaaatgatc atctaagaat cttgctacat cttcaagtgc
      961 tttatcatca tcaatttcaa ttttatattt ttttctattt aagtatgtgt caattactat
     1021 acttatccat tcatttgcct ttgctttaaa gaaaaaatca gcggcaggag cgtccatctt
     1081 acaatttaat atttccattg ccactctttc taaggccttt gtaagtatta tttgattcgg
     1141 ttgaagcaag gttgaataaa aagattctgg attaatgtta atagatgcta aatgtttttc
     1201 tattagctct tttttaaaac caatggaaac agcaagataa caacaattct cgtgtaataa
     1261 aaaaacaaaa tcatctttta tattatcaaa atcaaaagta cataaagagt ttgcggtaat
     1321 agtttgatac ggattaaact tttctccgtt tgcactgaca atgtaacttg aataaattga
     1381 aacatagtct gacatactat aagtgctatt ttgaactact tcctctttga tataaaaatc
     1441 atgtatatcg ataatgaagc tgcctccttc ataaaaccaa tataggcctt ctgcataagt
     1501 tgaattctct tttttccaac aaaatgtatg acctgcactt gaatacttct cattgttttt
     1561 acattcatct actttcatat aatcttttac aaaatcataa tatgacataa cacactatcc
     1621 cttttagaca atattccaat tagccttatt aattcaaaac tattgtatta gtaattataa
     1681 cagatgtata atagaaaagc aatgatagat attatcaatt aagcgaattt atatctaaaa
     1741 gggatattaa agaaaggaga tatgcttatg aagatttaca aaaaactatt tgcttatgtc
     1801 caagataaga aatatcttgg ggttttggcc ataatttttt ctgctatatc tgctctactt
     1861 acagtatatg gatattattt aatctacaaa tttctagata agttaataat taattcaaat
     1921 ttatccggtg cagagagtat agcattaaaa tctgttatta cactaacaag tggagcgata
     1981 ttttattttg tctcaggaat gttttcacac atcttgggat ttaggcttga aacaaattta
     2041 agaaaaaggg gaattgatgg cttagagaaa gcaagtttta ggttctttga cttaaatcca
     2101 tctggtcaaa taagaaagat catagatgat aatgcagcac aaactcatca ggtggtagca
     2161 cacatgattc ccgatagttc tcaggcaata atcacacccg tacttgtact tgcacttggc
     2221 tttatagtaa gtataagagt tggcataatt ttgcttgctc ttactataat tggcggctta
     2281 attttagggg caatgatggg cgagcaagaa tttatgaaga tataccaaga atccctatct
     2341 aaactaagtg ctgaaactgt tgagtacgtg agaggaatgc aagttgtaaa aatatttaaa
     2401 gcaaatgtag agtcttttaa aagcttttat aaggcgataa aagattactc aaagtatgct
     2461 tatgattatt ccctatcttg taaaaggcct tatgttttgt atcaatggtt attttttgga
     2521 ctgattgcaa ttttaattat tcctatagtt tattttatga ctagcttagc tagcgcaaag
     2581 gtgattttac ttgagcttat catgatttta tttttatcag gagttctctt tgtttcattc
     2641 atgagaatga tgtggtactc catgtatatt tctcaaggaa attatgcagt agatacttta
     2701 gaggcgcttt acgaagatat gcaaaaagac aaattagtgc atggtaatat caataatttt
     2761 aaaaactata atatagaatt tgagaatgtt agctttgctt ataatgataa agctgtcatt
     2821 gaaaatttat cctttaattt agaagaagga aagtcctacg cacttgtcgg ttcatctgga
     2881 tcaggcaaat caacagtagc aaaacttata tcaggttttt ataatgttaa taaaggaagc
     2941 ataaagatag gcgggatagc aataagtgaa tattctgacg aagccttaat taaagccatt
     3001 tcctttgttt ttcaagattc aaaattattc aagaagagca tttatgataa tgtagcttta
     3061 gctaataaag atgcgacgaa agatgacgtt atgagagcct taaaattagc aggatgcgat
     3121 ttaatattag acaaattccc agaaagagaa aatacaatca taggctcaaa aggtgtttat
     3181 ttatccggtg gagaaaaaca aagaattgca attgctagag caattttaaa ggattccaaa
     3241 attattatta tggatgaagc atcagcatct attgacccag ataacgagtt tgaattgcaa
     3301 aaagctttta aaaatcttat gaaggataaa acagttatca tgattgcaca caggctatct
     3361 acaattaaag accttgatga aattattgtc atggatagtg gaaaaattat agaaagaggg
     3421 tctgacaaag aattaatgtc aaaagataca aggtataaga gcctgcaaga gatgtttaac
     3481 agtgcgaatg aatggagggt ttcaaatgaa agagttttat aaaaaaagat ttgctcttac
     3541 agatggagga gcaagaaatt taagtaaagc aacactggct tcatttttcg tttattgtat
     3601 aaacatgctt cctgccatat tacttatgat ttttgctcag gaagttttgg aaaatatggg
     3661 caaaagcaat ggcttttata tagtattctc agttttgact ttgatagcaa tgtatatttt
     3721 gctttctatc gaatacgata aattatataa cacaacctat caagaaagtg cagatttaag
     3781 aataaggaca gcggagaatt tatcaaaatt acctctatct tacttttcta aacatgacat
     3841 ttccgacatt tcacaaacaa tcatggctga tattgaaggc atagagcatg caatgagcca
     3901 ctcaatacca aaggtgggcg gcatggtact gtttttccca ttaatatctg taatgatgct
     3961 agcgggcaat gtcaagatgg gtttagctgt aattattcca tctattttaa gctttatatt
     4021 tataccttta tctaaaaaat atcaggttaa tggacagaat agatattatg atgtcttaag
     4081 aaaaaactca gaaagctttc aagaaaatat cgaaatgcaa atggagatta aagcatataa
     4141 tttatcgaag gatattaaag atgacttata taaaaaaatg gaagatagtg agagagtaca
     4201 cttaaaggcg gaagtaacta caattttaac tttgtctata tcttcaatat ttagctttat
     4261 atctcttgct gttgtgatat ttgtcggcgt aaatctaatt attaataaag agataaattc
     4321 tctctacctt ataggatatt tactagctgc tatgaagata aaagactctt tagatgcatc
     4381 taaagagggc ttgatggaaa tattttattt atcgcccaaa atagaaagat taaaagaaat
     4441 tcaaaatcaa gatttacaag aaggcgatga ctatagctta aaaaaatttg atattgatct
     4501 aaaagatgtt gagtttgcct acaataaaga cgcaaaagtt ttaaatggtg taagttttaa
     4561 agctaagcag ggagaggtca ctgctttggt aggtgcaagt ggctgcggta aaacaactat
     4621 cttgaaactt atatcaagac tttatgatta tgacaaggga caaatcttaa tcgatgtcaa
     4681 agatataaaa gaaatatcaa cagaatctct ttttgataag gtctctatag ttttccaaga
     4741 tgtggttctc tttaatcaaa gcgttatgga aaatattaga atcggaaagc aagatgcaag
     4801 tgacgaagag gttaaaagag cagcaaaact tgcaaattgc acagatttta tagaaaaaat
     4861 ggataaaggt ttcgatacag ttattggtga gaacggagct gagctatcag gaggagaaag
     4921 acaaagatta tcaatagcca gagccttctt aaaagatgcg ccgatattga tcttagatga
     4981 gataacagca agccttgatg ttaacaacga gaaaaagatt caagagtctt taaataattt
     5041 agttaaagat aaaactgttg taatcatttc acatagaatg aaatccatag aaaatgcaga
     5101 caagatagta gttcttcaaa acggaagagt agaaagcgaa ggtaagcatg aagagctttt
     5161 acaaaaatca aaaatttaca aaaatttaat agaaaagaca aaaatggcag aagaatttat
     5221 ttattaggag gactacaatg gataataaaa aattaaaagt aaaagattta gtaagtatcg
     5281 gtgtttttgg cgtaatttat tttgccttca tgtttggagt tggtatgatg ggcttgattc
     5341 caatattgtt cttaatatac ccgacagtat tagccatagt tgcaggaact gttgttatgt
     5401 tatttatggc taaggttcaa aagccatggg cactatttat atttggtatg atatcaccac
     5461 ttgtgatgtt tgcagctggt catacctacg tagttgtggt tttatcactt atagtaatga
     5521 taatagcaga attaattaga aagattggta attataattc atttaaatac aatatgcttt
     5581 cttatgcaat cttcagcaca tggatatgta gctctttaat gcaaatgctt ttagcaaaag
     5641 aaaaatatat ggagtggtct ttgatgacga tgggaaaaga ttatgttgat gtattagaaa
     5701 agttaataac ttatcctcac atggctttag tagccttagg tgctttctta ggaggaattc
     5761 ttggagcata tataggcaag gctctattga aaaaacactt tgaaaaagca ggcatcgtat
     5821 aatgcctact ttttcttcaa atgctccctt taatcccaat ccgatctcta agatattagt
     5881 cgtatttatc acaggcttaa ctgttatgca tagcataaac atccgttttg agctggcaat
     5941 tgtttgtctt attggtattt tgctttattt gaatggatac aaaaaaacac ttttcaaatg
     6001 gattatattg tgtgggatac tttactcctt gcctaatttt atggtgttat ctgaattaaa
     6061 ccctatagtt aagatgtttt tgagtatacc tattgttatt agaatgttta ttttaccatt
     6121 tatggcagca agctttatga taaagacctc ggatgtaggc gcaataattt catcgatgga
     6181 taagcttaag atttcaaaga atgtatccat acctattgcg gttatgttta gattcttccc
     6241 atcttttaag gaggagaaga aaaacatcaa aatagctatg agagtaagag ggataaattt
     6301 taaaaaccca gtcaaatatc ttgaatatgt ttctgtgcca ctactcatta tatcatctaa
     6361 tatatcagat gacattgcaa aagcggcaga aacaaaggca atagaaaatc caattgccaa
     6421 gaccagatac attcgcgtaa agatacagct aattgatttt gtttatgttt tagcggttgc
     6481 tggacttatt gtgggaggct taatatggtt gaaataaaaa atttaagtct tgattatggt
     6541 gaagagcata tattagatga tatatcacta tccatagccg agggagagtg cgtgctattt
     6601 acaggaaaaa gtggaagtgg taagtcatct ttaataaatt caatcaatga actagctgta
     6661 aggtatgata acgcaaagac aaagggcgaa ataattattg atggtaagaa tataaaaaat
     6721 ttggaacttt atcaaatctc aatgcttgtt tcaactgttt ttcaaaatcc taagacatat
     6781 ttttttaatg tcaatacgac attagaatta ttattttatt tggaaaatat cggtcttgca
     6841 agagaagaga tggacaggcg tttgaaggat atgcttgaga tattcccgat aaaaaatctt
     6901 ttgaacagaa atatatttaa tctatccggc ggtgaaaaac aaattctttg cattgcagct
     6961 tcttatatag caggtacaaa gattatagtt atggatgagt cttcatcgaa tttagatatt
     7021 aaaagcataa gtgttttggc aaagatgcta aagatattaa aagagaaagg cataagcata
     7081 attgttgcag agcatagaat ttattatttg atggacatag ttgaccgtgt atttttaata
     7141 gataaaggaa agcttaaaaa aacttatact agaagtgaat ttttaaagct agataaaaat
     7201 gaattaaatg ctttaagttt aagagataaa gaattaagta aattaaaagt tccttattta
     7261 aaagaaggtg gagagtatca gataaaaaat cttagctaca aatttactga tgatgagtgt
     7321 ttaagcttaa aagatatttc gttcaagctt gggaaaattt atggcataat aggatccaac
     7381 ggacgaggaa aatcaacgct tttaagatgt ttaataggtc ttgagaaaaa atcaaaagaa
     7441 gaaatttatt ttaagggaga gaagctatct aaaaaagaaa gactcaaaaa ctcttcactt
     7501 gttatgcaag atgtaaatca tcaattattc acagatgaag tattcaacga gcttagatta
     7561 ggagtaaaga attttgatga agaaaaggcg aaaatcattt taaaagattt aggcctggac
     7621 gaatttattg aaaggcatcc gatgagttta tcaggagggc aaaagcaaag gcttgcaata
     7681 gcatctgtta tgtgcaagaa ttctccattt gtcttttttg acgaaccttc aagtggtatg
     7741 gattattcca atatgataaa aatatctgaa ctgattaata agtataaaac catggataaa
     7801 ataattttta ttgtttccca tgatatagaa tttttaaatg aagtggcaga tgaaattttt
     7861 gaattgtaaa atagagtctg ttaaacatgt ctatagaact ggtaaattgt ctaaaaattt
     7921 aaaagatac
//
LOCUS       DAVLHM010000067         7915 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLHM010000067 DAVLHM010000000
VERSION     DAVLHM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.067"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(172..2169)
                     /gene="metG"
                     /locus_tag="VXE45_001935"
     CDS             complement(172..2169)
                     /gene="metG"
                     /locus_tag="VXE45_001935"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0789920.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2293..3552)
                     /locus_tag="VXE45_001936"
     CDS             complement(2293..3552)
                     /locus_tag="VXE45_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0789921.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3554..4255)
                     /locus_tag="VXE45_001937"
     CDS             complement(3554..4255)
                     /locus_tag="VXE45_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789922.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4239..5438)
                     /locus_tag="VXE45_001938"
     CDS             complement(4239..5438)
                     /locus_tag="VXE45_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0789923.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5724..7070
                     /gene="gor"
                     /locus_tag="VXE45_001939"
     CDS             5724..7070
                     /gene="gor"
                     /locus_tag="VXE45_001939"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0789924.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7267..7803
                     /locus_tag="VXE45_001940"
     CDS             7267..7803
                     /locus_tag="VXE45_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0789925.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT         2252 a         1761 c         1500 g         2402 t
ORIGIN      
        1 tcagtttcat ctacaacctc aaagcagtgc tttgagctga cttcgtcagt ttcatctaca
       61 acctcaaagc agtgctttga tcaacccgcg gctagcttcc tagtttgctc tttgattttc
      121 attgagtata aataaaaaaa cagaactagc ctgaactagt cctgtctact tttacccaat
      181 cacacttcca tttggtacag ctggatcaac tgtgagaagg gttaatttgc catcatgttc
      241 agctgagaga atcataccct ggctgacata ttttttcatc attttacgtg gtttgaggtt
      301 agcaacgatt tgaactttct tgccgaccaa ttcttgttca tttggatagt attttgcaat
      361 tcctgaaaga atctgacgat cttctccatc accagcatcc aagcggaatt gaagcaactt
      421 atctgaacct tctactttag acacttcttt gacttctgcg acacggattt caaccttgtc
      481 aaagtcttca aacttgattt catccttgtt tagtttgagc tcaacttcgt ccggattcca
      541 ttctttttcg actgctggtt tattgccttc catttgttcc ttgatatagg cgatttcttc
      601 ttccatattt agacgtggaa agataggtgt tcctttggca actacagtca catctgctgg
      661 gaagtcagcc aaactcaagt tttcaagact agaaacttct tccaaaccaa gttgagtcaa
      721 aactgcacga ctagtttcca tcataaatgg ttcaatcaag tgagcaacta cacgaatgct
      781 ggctgccaag tggctcatga cacttgccaa ttggtcacga agagcttcat ccttgtccaa
      841 gacccatggt gcagtctcat cgatgtattt attggtacga gagatcagag tccagactgc
      901 ttcaagcgca cgtggatagt caactgcttc catgtgtgta tggaagtctg cgattgattg
      961 ttctgcaacc tcagcaagaa catgatcaaa ttcagtcaca ccttctacat aggcagggat
     1021 ttgtccatca aagtacttat taatcatgga aaccgtacgg ttaaggaggt tcccaaggtc
     1081 attagccaat tcatagttga tacggccgac atagtcttca ggagtaaagg ttccgtctga
     1141 accaactgga aggttacgca tgaggtagta acgaagtgga tctagtccat aacgctctac
     1201 caacatttca gggtaaacga cattcccttt tgacttagac atttttccgt ctttcatgac
     1261 aaaccaacca tgggcaatca aacgatcagg taatttaaca tccaacatca taagaaggat
     1321 tggccagtag atagagtgga agcgaaggat atcttttcct accatatgga agactgttcc
     1381 attccagaac ttgtcaaagt taccatgttc gtcttgagcg tagccaagag ctgtcgcata
     1441 gttaagaagg gcatcaatcc aaacgtagac aacgtgtttt ggatttgatg ggacaggcac
     1501 tccccatgta aaggttgtac gagataccgc caaatcttcc aaacctggct cgatgaagtt
     1561 gcgtagcatt tcattaaggc gaccatctgg cgtgataaat tcaggatgag ctttgaaaaa
     1621 ttcgaccaaa cggtcttggt atttgctaag gcgaaggaag tatgattctt cagaaaccca
     1681 ttcaacctca tgacctgatg gagcaatacc accagtcaca tttccagctt catcacggaa
     1741 aacttctgcc agctggcttt ctgtaaagaa ttcttcgtct gatactgaat accaaccaga
     1801 gtattcaccc aagtagatat catcttgagc aagtaagcgt tcaaagacct gtgcaacaac
     1861 tttttcatgg tagtcatcag ttgtacggat aaatttatcg tatgagatat ctagtaattg
     1921 ccagagttct ttaactccaa ccgccattcc atcaacatag gcttgaggtg taataccagc
     1981 ttcttccgct ttctgctgga ttttctgacc atgttcatca agacctgtca gataaaatac
     2041 atcgtagccc atcaggcgtt tgtaacgtgc taggacatca catgcgatag ttgtgtaggc
     2101 agaaccgata tgaagtttcc cagatggata gtaaatcggc gttgtaatat aaaaattttt
     2161 ttcagacata atttttcctt tccaggcaaa tgaaacctgt ttttctaaca cttcattata
     2221 tcacattttt aatgaatttc gatagggaaa tccatacaaa aacaagatag acgagtgtcc
     2281 atcttgttga tctcattcat aacgaagggc ttcaattgga tcaagtttcg atgccttgtt
     2341 ggctggcaag actccaaaaa tcataccaac actagccgaa actgcaagac taaatagggc
     2401 aactgggatt gatactccaa cttctatacc ttctattaaa ccttgcagta acaaacctgc
     2461 taaggcagtt aaaccacttg caattgtcaa gccaattaag ccacctaaca aggtcaaaat
     2521 catggattca atcaaaaact gaattaaaat attggcacgt gttgcgccca aagccttacg
     2581 aagaccaatc tcacgagtgc gctctgtcac cgaaaccagc atgatgttca tgacaccagt
     2641 tcctccaaca aagagagaaa tccctgcgat ggaactaata atcgtcgtca taaaactaaa
     2701 cgattgttga atttctgcaa atacaacgga ctcatctgcc acctggtatt ctccctgttg
     2761 taagcctgca agctctgtca tttttcgtgc cagttctgga cccagagttg gggttaaact
     2821 ggtatcattc actcgaaaga caatattagc tatttcatct acattaaaat tcgcagcaag
     2881 ggagatattg gtagtaatag gcaagccacc aaacccatat atttttgatc ttttagcctc
     2941 cggactagta taaaccccaa tgacccggta actaaatcca ttgacttcta caaccttgtt
     3001 aatagcctct tgaggagatt caaataaact aatggacaat tcctcatcta gcaaaatgac
     3061 acttgcaaac tctttgaaat cttgctctct cagactacga cctgcaataa tttcattctt
     3121 aacagcgtcc atgtaagttc tgtttccacc tgtcaaatta gcattctcaa cctttttatc
     3181 ttgataggtc aagatggcat tcgttgaatt ggttacatag taactatcca ctcccttcag
     3241 tttagctgcc tcttggaccc aggattcttg cggttttggc ggttcaacag gaacttcctc
     3301 ttcctttcca gaaaccgtaa aagctgattg tttctgagta aaagacccgt ctttactttt
     3361 tttaggagaa aaaaagacgc taatattttt ctgagattta gtcatatctt tattgacttg
     3421 acgagatagg gaatcaccca aagccataat cacaacaact gatgaaacac cgataataat
     3481 cccaatcata gtaagcaaag aacgcatctt gtgagccatg atagatgaaa aggcaaattt
     3541 cagattctgc atcttagttt tcctcctttc ctaactgagc actgtcagac gaaatgaccc
     3601 catcccgaat gacaatctga cgtttggcat aggcagcaat ctcaggctca tgcgttacca
     3661 tgataatggt ttttccttct ttattcaaat caaccaataa ttgcataatt tggttacctg
     3721 ttttggtatc caaggctcct gtcggttcat ccgctaggat aatagaagga ttgtttacca
     3781 aggcacgcgc aatggctaca cgttgctttt gaccaccaga taattctgaa ggtaaatggt
     3841 gactacgttc tgtcaattca accttgtcta aatattcctc agccaacttg cgacgttttg
     3901 aagacgaaac tcctgcgtaa atcaagggca attctacatt ttgcagagca ttgagcttcg
     3961 atagaagaaa gaactgctga aagacaaaac cgatttgttg gttacggacc ttagctagtt
     4021 gtttttcacc cagcccagcc acttcttgac cttcaagata atattctcca ctggttggtg
     4081 tatccaacat gccaatcgta ttcatcagag tggacttacc agacccagat ggtcccatga
     4141 tggctacaaa ttcaccctca ttcacttcta gattgatatt tttgagaacc tgcagttctt
     4201 ggtcaccatt acggtaactt ctgaagatat tttttagact aattagttgc ttcatcagcc
     4261 ttcacctctt ttccttcttc caaggaagat gttggattac tgatgacctt agcaccgttc
     4321 gttaaaccag aagtgatttc ttgattttct gcgtcagcat ttcccaatga aacctcaact
     4381 tttttagcct tttgttgttc atccacaatc cagacataat ttttactatc atccattact
     4441 agactgctaa caggaacaag aatagcctta gttttgcttt taacctcaat gttgacagaa
     4501 aaaccttgtt tcaaatcacc aacctcgcct gtcacatcaa tagtataagg gtatttagaa
     4561 cctgtattat tcccggctgc tggactagct gcttcaccat tgtttttagg atagtcagaa
     4621 atatagctta atttcccagt ccatttttta tcaggataca ctttagaagt aaagcttact
     4681 tcttgaccta cagaaaggtt ggctagattg tactcagaca attctccctt gacttgtaaa
     4741 ttttcattgc tgacaatatg aaccataact tggctcgccc ctgttggaga tttagaaaca
     4801 ttgctattga cttcgactac agttccctct agggtactga gaacagttgt tgcatccaat
     4861 tgactttgag ccttgcttaa ttgcgccgca gcatctgcac gcgcatcacg ggcatcaccc
     4921 aattgagcat caatagaagc aacagaattt ccagccactg gagttgggct ttgcaccgtt
     4981 gcatcttctc ctcctactgg cgctggtaac tgtggagccg gagctgaagc ggcttcattt
     5041 cgtgcttgat tgagttcatt gatatgacga tctgccctag ctactgctcg actagctgaa
     5101 tcataggccg cctgcgcttc tgaactactg tacttgacta aagcctgccc ttcgctgacc
     5161 ttatcgccca cagaaacaag gatttcatct aaatcaccct tactagcatc aaaataaaca
     5221 tattgttcat tttttgctgt tactgtccct gacaataaaa cagaggatgc cacgcttcct
     5281 tccttggcaa caacaagatg agtaggctca tcttttagag cagtctgaga aggttgtcta
     5341 aaaagtaaaa tccccccggc acccaataca actacactcg cagcaccgat tgctgcatac
     5401 agttgccact ttttagcttt accattcttt ttcttcataa tgaaactcct tttctttttt
     5461 acaatacttt gctattatac caaatttccc tccagcaaac aatgcagttc agatggaaat
     5521 aatggcagtt caggattaaa caatcgttcg gaattttgct tttctattgt actagatata
     5581 taatacacta tcttgactta tttggcaagc ttttttgcaa ttttttgtgc gtagcagatt
     5641 tttgcaatca aatcaaaaaa agaataaaat ataactatca aaaaagacgc tctactattt
     5701 aaaagattac aaaggagttt tcaatgagag aatatgatat cattgctatc ggtggaggta
     5761 gcggaggaat cgctaccatg aaccgtgctg gtgaacatgg agccaaagca gccgttattg
     5821 aggaaaagaa attaggtgga acctgtgtca acgtcggttg tgttcctaaa aaaatcatgt
     5881 ggtacggggc gcaaatcgct gagactttcc atcaatttgg agaagactac ggctttaaga
     5941 ctactgatct taactttgac tttgcaaccc tacgtcgcaa tcgtgaagcc tacattgatc
     6001 gcgctcgttc ttcttatgat ggtagtttta aacgcaacgg tgtagacttg attgaaggtc
     6061 atgctgaatt tgtagattct catactgtaa gcgtaaatgg tgaactgatt cgtgctaaac
     6121 atatcgtgat tgctacaggt gcccatccaa gtattcctaa tattcctggt gctgagctag
     6181 gtggctcttc tgatgatgta tttgcctggg aagaacttcc agagtcagtt gccattctag
     6241 gcgctggtta tatcgccgtt gaattagctg gcgtactcca cacttttggt gtcaagacag
     6301 atctctttgt tcgccgcgat cgtcctttac gtggttttga ttcctacatc gttgaaggtt
     6361 tggtcaagga aatggaaaga acaaacttac cacttcacac tcacaaagtc cctgtcaagt
     6421 tagaaaaaac tactgacggc attaccattc atttcgaaga tggtactagt cacacagcta
     6481 gccaagttat ctgggctaca ggccgccgtc caaacgttaa gggcttgcaa cttgaaaaag
     6541 ctggagtgac tctgaacgaa cgtggcttta tccaagtgga tgaataccaa aatactgttg
     6601 ttgagggact ctatgctcta ggtgatgtaa cgggcgagaa agaactgact ccagttgcaa
     6661 tcaaggccgg acgtacccta tctgaacgtc tctttaacgg aaaaactact gcaaaaatgg
     6721 attactcaac tattccaact gttgtctttt cacaccctgc tatcggaact gttggtttga
     6781 cagaagagca agctattaaa gaatacggtc aagaccaaat caaggtttat aaatcaagct
     6841 ttgcatctat gtactctgct tgcactcgca accgtcaaga atcccgtttc aaactcataa
     6901 cagctggttc agaagaaaaa gttgtcggac ttcatggaat tggctacggc gttgatgaaa
     6961 tgattcaggg atttgccgtt gctatcaaaa tgggagcaac caaggctgac tttgatgcaa
     7021 ctgtggcaat tcacccaact gcatctgaag aatttgtaac catgcgttaa tcgaaacaaa
     7081 agaagctgat ataaatatgt ctgcttcttt tttaatgatt ttcgaatcaa caaaaaaatt
     7141 atccaacttg actagtcacg aaaatcggct gttacagttt ttgttacctt gtttttaaaa
     7201 aatggttgac atcgactcct atatgagtat aatagttact atacattaga aaagaggtta
     7261 actattttga aaaaagctca cgtttatgct atccctgcta ttggggctgc tctcattgct
     7321 gctttggcac aaatcagtct tccaattgga cctgttccct tcactctgca aaactttgca
     7381 atcggcttga ttgctactgt ctttagaccg agagaggctg tactttctgc tggactctat
     7441 cttcttctag gtgctatcgg tcttcctgtc tttgcaggag gtggagctgg ttttcaggct
     7501 ttagttggcc ctactgcagg ctatctttgg ttttatctcg tttactctgg acttacttcc
     7561 tctctaacca acagcaagag tggtgttgtt aagatttttc ttgcaaacct cttgggtgat
     7621 gcccttgtct ttgtcggcgg gattctcagc ttgcatttcc tagctggaat ggcatttgaa
     7681 aaagctcttg ttgtgggggt tcttcccttt atcattccag accttggcaa acttctggct
     7741 attagtttta ttagccgtcc cctacttcaa cgccttaaaa atcaggctta ctttactaac
     7801 taaaaaagga taccgagtta tcatgactca atatcctttt cttttatttt gaaaacttat
     7861 actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca aaaca
//
LOCUS       DAVLHM010000068         7741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLHM010000068 DAVLHM010000000
VERSION     DAVLHM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.068"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..459
                     /locus_tag="VXE45_001941"
     CDS             <1..459
                     /locus_tag="VXE45_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0789926.1"
                     /translation="RYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLK
                     HHYQIYQLLLFHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHY
                     SNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(494..916)
                     /gene="nusB"
                     /locus_tag="VXE45_001942"
     CDS             complement(494..916)
                     /gene="nusB"
                     /locus_tag="VXE45_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0789927.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(909..1298)
                     /locus_tag="VXE45_001943"
     CDS             complement(909..1298)
                     /locus_tag="VXE45_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0789928.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(1320..1880)
                     /gene="efp"
                     /locus_tag="VXE45_001944"
     CDS             complement(1320..1880)
                     /gene="efp"
                     /locus_tag="VXE45_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0789929.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(2009..3451)
                     /gene="gatB"
                     /locus_tag="VXE45_001945"
     CDS             complement(2009..3451)
                     /gene="gatB"
                     /locus_tag="VXE45_001945"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0789930.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(3451..4917)
                     /gene="gatA"
                     /locus_tag="VXE45_001946"
     CDS             complement(3451..4917)
                     /gene="gatA"
                     /locus_tag="VXE45_001946"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0789931.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDTDNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSASVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(4917..5219)
                     /gene="gatC"
                     /locus_tag="VXE45_001947"
     CDS             complement(4917..5219)
                     /gene="gatC"
                     /locus_tag="VXE45_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0789932.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5432..6976
                     /locus_tag="VXE45_001948"
     CDS             5432..6976
                     /locus_tag="VXE45_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0789933.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            7231..7428
                     /locus_tag="VXE45_001949"
     CDS             7231..7428
                     /locus_tag="VXE45_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0789934.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            7539..7715
                     /locus_tag="VXE45_001950"
     CDS             7539..7715
                     /locus_tag="VXE45_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0789935.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
BASE COUNT         2175 a         1531 c         1762 g         2273 t
ORIGIN      
        1 cgttactgga aactcatcca acaggatagt cgtaaattga gcgataaacg tttttatcgc
       61 cctacttttc gcatgcactt aacaaataaa gaaattcttg acaagatttt aagctattca
      121 gaagacttga aacaccacta tcagatctat caactcttac tttttcactt tcagaataag
      181 gaaccggaga aatttttcgg actcattgag gacaatctga agcaggttca tcctattttt
      241 cagactgtct ttaaaacctt cctcaaagat aaagaaaaga ttgtcaacgc ccttcaacta
      301 cactattcta atgccaaact ggaagcgacc aataatctca tcaaacttat caagcgcaat
      361 gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga tttttatcgc tttgaacatc
      421 aaaaaagaaa ggacgaaatt tgtcctttct cgagcttagc ttttcttcaa cccactacag
      481 ttgacaaaga gccttattgt tcttctgtta caaactggct gagcagtcca ttgataaaac
      541 gggcagattt ttgatcggag aagtcctttg caagctcgat agcttcatta acagcaacca
      601 gctgaggagt gtcaaatgaa gtgatttcaa agactcccaa gcgaaggagg tttctctcca
      661 cgagcgttaa gcgttcaatg gtccaacctg cttttaaatg ctgagtgatt tgcttatcta
      721 gttcttcctt tttagcttga acaccagaaa cgaggtctat caaaaaggct ggaagttgta
      781 catccgtata ttcacgatca tgagtatagg cgaaacgaca agcagtttcg acatccgtac
      841 cgaactcaag gctcatgaga gcttgaaaag cgcatttacg gagttggcgt ctagattcta
      901 atagtggact agtcattgag gaagtcctcg tcaaatagat ctttcaattc tggttttggt
      961 gttttatctg ggacgatacc tgcaacgtga atattgatag cagcgagttc tacatcagcc
     1021 atattacgga cggcatcttt gacagctttc tggatagcaa ccgctacctt aggaactttt
     1081 actccgtact caaggtagag atagatatct gctgtgagtt cttcgtccac gtttttaaga
     1141 taaatgccac ggccgagtga aagttttgaa agggtatcag acactgatct gtttgaaaaa
     1201 gagtgaacac cctctacctt tgcagtagcg atagcaatga ttttttcaag tacacgtggg
     1261 gcgataacga tttcgccaag ttgttcttca attcccatag aatgacctct ttctagagat
     1321 taggcacgag aaacgtaagt tccttctgca gtgttgataa cgagtttttg tcctgcttcg
     1381 atgaagtctg gaacgtttac gacaagtcca gtttccatcg ttgctggttt accagaacct
     1441 gtaacagtag cacctttgat agatggttga gtttcagcaa ctgtcaactc aacagtagta
     1501 ggaacggtga caccgatcac ttcagttccg tagaattgga ttttcacatc agagttttca
     1561 aggatgtaaa gcaattcgtt ttcaacattg actacaggga tttcgtattg gtcgtaagtt
     1621 tctgtattca tgaagtatgc tgtgtcatcc attttgtaca agtattgagc tgggacagtc
     1681 tcgataatag cttgttcaaa tttttcctct ggacggtagc ttgtgtcaaa tgtagaacca
     1741 gtacggacat cacgcaattt catacgcatg atcgtgtttc ctttacctgg tttgtggtga
     1801 ctagcttcca aaacgcgaat caatttgccg tcagctgttt caaaggtcat accagctttt
     1861 aatttacttg cttcaatcat gtttttacct ctttaataaa tattattact cttcatttta
     1921 ccataaaata ctctggaaat aaagccaaaa tagttattgg gagttggtag agaagaaaaa
     1981 accaacctta gggctggttt tgttctgtct agttttcttt caacttcgcc aattcctgtg
     2041 caagtagttt aagggcaact tgtgggttgg cttggccttt ggttgccttc ataaggaatc
     2101 ctgtaaaggc cttgtcggcg ttacgtttgc ctgacttgaa gtcggcaaca gcagcttcgt
     2161 tatcggcaaa gacttggtgg atgattggga tcaagatagc tggatctgaa atttgaacca
     2221 tacctgcttt ttccacgtat tcacgcgcgc caccgccatt tttagctaga tggacaaaga
     2281 ctttcttggc aatcttagat gaaatagtac cgtcttcgat gatggtaatc atttcaacca
     2341 agttttctgg tgtcaattcg atttgttcca gtgttttacc ttcagcattc aagaactgag
     2401 cgacttcccc ttggagccag ttagagactt gtttggcatc accacctagg gcaacagctt
     2461 tttcaaagaa gtcagaagtg actttattag cagtcaactg actagcatcg tagtctgata
     2521 aaccaaggtc agatacataa cgcgcacgac gttcttttgg aaactctggc aactcagtcc
     2581 gcatttcctc aatccactcg tcagaaattt caaagagggg taggtctggt tctgggaagt
     2641 agcggtagtc agcagcccct tccttgacac gcatgaggat ggttgttttg ttagcttcat
     2701 cgtaacggcg tgtttcttgg cggatttgac cacctgagcg aagaatttca gcctggcgtt
     2761 ggacttcgta ttcaagacct ttacgaacgt ttgagaagga gttgaggttc ttcaattcag
     2821 tcttggtacc gaatttttct tgaccataag gacgaaggga gatgttggca tccacacgca
     2881 tagaaccttc ttccatctta acgtcagaaa tgccagcgta ctggataact tccttgaggg
     2941 ctgtcagata agcataggct tcttcaggag aacgcatatc tgcctcagat acaatctcaa
     3001 tcaagggaac cccttggcgg ttgaggtcaa cataagagta gccatctgta ccatgggtgt
     3061 ttttaccagc gtcttcctct aagtgggcac gttcgatacc gattttcttg gtcgtaccgt
     3121 cttctagttt gacttcaatc cagccattat atccgattgg ttcatcaaat tgagaaattt
     3181 ggtaggcttt ggggttatca ggatagaagt agttcttgcg gtcaaagtgc atctttttgt
     3241 ggatgtccat gttgagggca agagcagcct tgataccggc atcaacaacc cctttattga
     3301 gaactggtag aactcctggg aaagaccagt caattacgtt agtgttggca ttttggtcat
     3361 ttccgaagtg ggcagaagta ggtgagaaga tttttgaatt ggtgttgagc tctacgtgga
     3421 cttcaagtcc gatgactgtt tcaaagttca ttagttgtca cctccaaaaa tcacgggttg
     3481 ttgtttgtgg tagtctgttg ttgcttcaaa agcagcagca gcttggtaaa tggtttcctc
     3541 agagtacttg ggaccaatca attggagtcc gacaggtaga ccttgagaga atccagcagg
     3601 aatcgaaatt ccaggcagtc ctgccaagtt tacaggtatg gtcaagaggt cggctaagta
     3661 catggcaact gggtcatggt tgagagaatc caagtcatag gcaacacttg gagcagttgg
     3721 acccaaaatc aaatcgtaat ccgcgaagac tttttcgaaa tcttgaatga taagtgtacg
     3781 gacctgtcca gccttcttgt agtaggcatc gtagtaacct gatgaaagac tgaaagtacc
     3841 cagcatgata cgacgtttta cctcttcacc aaaaccttgg cttcggctgt ttacatagat
     3901 ttcatcaagg ttggttgcat cttctgcgcg atagccgtaa cggataccgt caaagcgttg
     3961 caagtttgat gaagcttctg atgaagcgat gatgtagtat acggcaactc cgtatttaga
     4021 gtgaggaagg ctgacttctt cgacaatagc accaagtttt tcaaagtgtt tagcggcact
     4081 tagaatggtt tccttaacct ctgggttaat tccttcaccg aggtattcct taggcaaagc
     4141 gattttcata cccttgatgt cttggccgat ttttgaagta aagtcggcga tgcggacaga
     4201 agcagaagta gagtctttag catcttcgct ggcaatagcg ttgagcaaga gggcattttc
     4261 cttaacagta ggagcaaaag gtccaatctg gtctaatgag ctgccaaagg caatgagacc
     4321 gaaacgtgaa actgttccgt aggttggttt gagaccaacg attccgttga aggcagcagg
     4381 ttggcggatg gaaccaccag tatcagaacc aagtgacaag cgaacttgtc ctgaggctac
     4441 agctgcggca gaaccacttg atgacccacc aggaaccttg ctgtggtccc aagcgttttt
     4501 agttgctccg tagtgtgaag tttcacctga accacccata gcaaattcgt ccatgttggt
     4561 ctttccaacg acaatcatgc ccttggtttt tgcattggca acagctgtcg catcaaagat
     4621 tggctcatag ttgtagagca tttttgaggc agcagttgtg agaataccgt ctgtagagat
     4681 gttatcctta acagcaagtg gaattcctga aaggacattg tcagtatcaa ttccagcttc
     4741 atcaatggct ttagcttgaa caagagcttg ctcctcagcg atggtgacaa atgaattgag
     4801 ggcttcctca cgagacttga tattttcaag tgttgcttgg gtcaattctg ttgcagaaat
     4861 ttccttagag acaaggagat tgtgcaactc ttcaatagtt ttatcgttaa aagtcattag
     4921 gcatctcctc catcgtctag gatagctggc accttgatat agtagttgtc tttttcaggt
     4981 acgtttttaa acaagcgatc acggtctgtt ccttcttcgg ccacatcagg gcggagtaca
     5041 gtcttgcggt cagccatagt cgtagtaggt gcgacaccag ttgtgtcaac ttcgcccagc
     5101 aattcaacca tgtcaacaat cttagacaag gtggtcgcaa aggcagcagt ttcttcttca
     5161 gagaatctta attttgaaag attggcaacg tgtgttacct cttcttgcgt aattttcatc
     5221 ttgcatcctt tcgtgaaatg atgattttta gtctgttcta ttttaccata ttttcctata
     5281 aataagggag ggggaagtga aaagaaatag aaattgaaaa aaatgctaaa atccgatata
     5341 atggagtgtt gaaaggaatg gtaaaatcca atgtaaaaat cattctcagc tattgaaaca
     5401 agaaaaatag agaatcaaag aaagagaact tatgaatatt caagaagaaa ttaagaaacg
     5461 tcgtaccttt gccattatct cccacccgga cgcggggaaa acaaccatca ctgagcagtt
     5521 actctacttt gggggtgaga ttcgtgaggc tggtacggta aaagggaaga aaacagggac
     5581 ttttgctaaa tctgactgga tggatatcga gaagcaacgt gggatttctg ttacttcatc
     5641 tgttatgcaa tttgactacg acggcaagcg cgtgaatatc ttagacacgc cagggcacga
     5701 ggacttctca gaagatacct atcgtacctt gatggcggtg gatgctgcgg tcatggtcgt
     5761 ggactctgcc aaggggatcg aggctcaaac caagaaattg tttgaggttg tgaaacatcg
     5821 tggcattcca gtctttacct ttatgaacaa gctggaccgt gacggtcgtg agcctttgga
     5881 tctcttgcaa gaattggaag aaatcttggg cattgctagc taccctatga actggcctat
     5941 cgggatgggg aaagcctttg agggcttgta tgacctctat aaccaacgtt tagagcttta
     6001 taaaggggat gagcgttttg ccagtctaga agacggggac aaactctttg gtagcaatcc
     6061 tttctacgag caagtcaagg atgacattga gcttttaaat gaagctggga atgagttttc
     6121 agaggaagct attctggctg gagaattgac gcctgtcttt ttcggttcag ccctgacaaa
     6181 ctttggtgtg cagaccttcc ttgaaatctt cctcaagttt gctccagaac cacatggtca
     6241 caagaaaaca gacggtgaaa ttgtggatcc ttatgacaag gatttctcag gctttgtctt
     6301 taaaatccaa gccaacatgg atcctcgtca ccgtgaccgt attgcctttg tccgtatcgt
     6361 atcaggcgaa tttgagcgcg gcatgagtgt caatctccct cgtactggta agggggctaa
     6421 actatctaat gttacccagt ttatggcgga gagtcgtgag aatgtgacca atgccgtggc
     6481 aggtgatatt atcggggttt acgataccgg tacttatcag gttggggata ccttgacggt
     6541 tggaaaaaac aagtttgaat ttgaaccact gccaaccttt actcctgaaa ttttcatgaa
     6601 agtttctgct aagaatgtta tgaagcaaaa atccttccac aaggggattg agcaattggt
     6661 gcaagaagga gccgttcagc tttataagaa ttaccaaaca ggtgagtaca tgctgggagc
     6721 tgttggtcaa ctccagtttg aagtctttaa acaccgtatg gaaggcgaat acaatgcgga
     6781 agtggtcatg agcccaatgg gtaaaaagac cgttcgttgg atcaagcctg aggacttgga
     6841 tgaacggatg tcgtcaagtc gcaatatctt agccaaagac cgttttgacc aaccagtctt
     6901 tctctttgaa aatgactttg ccctccgctg gtttgcggac aagtatccag acgtagagtt
     6961 agaggagaag atgtgactca gtaccaacaa ttggaactaa agttccaaat tgttggacgc
     7021 tagtcgctat ttggcgaact agctaactgc ctcactaact acgtttggca aatgaaatcg
     7081 atttgtaaaa ctccgtgtcg taatgtaaaa attgtaaacc gtaatgggac ttcatctaaa
     7141 atctccactg gtatggtttt acgaacgaat aggcgaaaat aatggttacg tagaaacata
     7201 tgatgggaat aaaaagaaat gagataaaaa gtgaaagaag agaaaaaagc gattgtctta
     7261 ggtgcagata atgcttatat ggataaagtt gaaacaacaa taaaatctct ttgtgttcat
     7321 cattataatc ttaagtttta tgtttttaat gatgaccttc cgcgagaatg gttccaattg
     7381 atggaaaaaa gactagagac tttgaatagt gagattgtga atgtttagat tgacagtaat
     7441 attctgaaag gttatcgtct cccctttgag ggactttcat atgcggcttt tttaggtatt
     7501 ttattccaaa gtatgtaagc gagtctcgtg tactgtattt ggattcagat attgttgtaa
     7561 gaaaatcgat agatgagctg tgggatttgg acttgacggc tataccctta gctgcagtta
     7621 gagatgattt ttatacacat aattttaatt ctggtgttct gttaatcaac gatggcatgt
     7681 ggagagcaga aaatgtcacg caagacctga tttaagacac aaataaaaaa tcttccaatt
     7741 c
//
LOCUS       DAVLHM010000069         7713 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLHM010000069 DAVLHM010000000
VERSION     DAVLHM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.069"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(177..1592)
                     /locus_tag="VXE45_001951"
     CDS             complement(177..1592)
                     /locus_tag="VXE45_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0789936.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1605..3443)
                     /locus_tag="VXE45_001952"
     CDS             complement(1605..3443)
                     /locus_tag="VXE45_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0789937.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDESVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3461..4303)
                     /locus_tag="VXE45_001953"
     CDS             complement(3461..4303)
                     /locus_tag="VXE45_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0789938.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLT
                     KNLD"
     gene            complement(4603..7281)
                     /locus_tag="VXE45_001954"
     CDS             complement(4603..7281)
                     /locus_tag="VXE45_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0789939.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFDGDSEFFLCKRLKDKSQFVMERS
                     RFEEMFQLQSSHLTTQEKLQLFTSVFAGRYDVYAKNFINEQGKIQYFPSYDYGWKQLP
                     PEKRSFQTLTNSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKGLKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVVVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRAIEGEEKQFVYVDSRYEKVLIEDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYDAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            7530..>7713
                     /locus_tag="VXE45_001955"
     CDS             7530..>7713
                     /locus_tag="VXE45_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0789940.1"
                     /translation="MKLTYDDKVQIYELRKQGYILEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPD"
BASE COUNT         2543 a         1598 c         1070 g         2502 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 attaatcccc ctataaaata aagaggttta gaatttgatg tcttccaaac ctctttattt
      121 catattcaat gagatgttgc cttaaccgtg ataatatcta atcatcaata aacaaactat
      181 ttgaataagg attctccatt tgattcaatc actcctttat accaagtaaa ggacattttc
      241 ttatatcgat tgaatgtgcc atttccatca tcatttcgat caacataaat gagaccgtac
      301 ctcttagaaa gctgtgcagt ggacatagaa acgcagtcaa tacatcccca agacgtatag
      361 cccataattt ccacaccatc ttgtagagct tcagctactt gcaataaatg ttctttcata
      421 tactgaattc tataatcatc ttggactgtt aagttattaa attcatcttt tattagttga
      481 tctttagcac ctaatccgtt ttccactata aataatggaa tttgataacg gtcataatat
      541 ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc agaagactct
      601 aaataaggat ttactaagcc accaataata ttcccttctc ctgaattata ctgtgttgga
      661 agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac ggtataattt
      721 tttaataact ttgcatcttc agctgcaaac tctatgttaa tgtcattttc cttaaaatat
      781 ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga
      841 ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc
      901 atagctaata ccatacaccc caccttaaac tctgaattaa tctcacgagc aatttttgta
      961 accaaactcg aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga
     1021 ttctccttag gtatatctat tcctccacta gtaaacggta attccaaaac agagtttact
     1081 tcgttaaatg taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca
     1141 aatttttcat aaaaatgaat cattctccta tcaatccatc catgatattt tcttgctaaa
     1201 tataatggag tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt
     1261 tcatcaaaca attcatcata atatttcaac ccagcttcgt taggttcttc ctcatctcct
     1321 tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa
     1381 aacaaggata tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta
     1441 tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact
     1501 gataagccct taccatcttc attatatgct ccctctactt gattagctgc aacagctcca
     1561 ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt
     1621 aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca
     1681 ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc
     1741 aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta
     1801 ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca
     1861 ctctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca
     1921 tcaaatggtg cataaacctt accttcactt ggaataatcg ctactccgtc tccaattagt
     1981 ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga
     2041 gaaaatatca tttttttatt tgaaactcca gctttaactt ctaaattgct agaactctct
     2101 tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga aataaccgcc
     2161 acaattaaag catttacaat atttgatggt acatcagaat aaataaattg aggcaacgct
     2221 atcaaagatg ggacagcaaa tagatacgct ttaacactag taagacctgc aaataatccc
     2281 gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca
     2341 tataatgcag gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt
     2401 tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct
     2461 aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc
     2521 aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca
     2581 ccaagaatag ctaatgtaag ccatccagct acatcataca tttgcccaac tagatttgat
     2641 aatccttcac caacaattac tccaataggc ccgactacaa ctaaggcaat acagcttgat
     2701 actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa cagctggtgt taatttagca
     2761 atcatttttt caatatattt catcaaccaa accataataa gaattggaac gactgacgaa
     2821 ccataactag ctggtatcac aggtacacca aataaactaa gaggattccc tgattgcacc
     2881 atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt
     2941 acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca
     3001 tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt
     3061 ggtaaaataa ttaccaagac tttcagcata cctcccccta acattgctgg aatgattgga
     3121 gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga
     3181 acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca
     3241 tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat tacacctggt
     3301 atcttcttca catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt
     3361 gttacacaat gggtaactct attgacattt ttttcacctc caattacatc gaggattttt
     3421 tgtaccttat ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta
     3481 agcgacgaat atgagccatc aaataaacta attcactaga agtcagcaaa taattgtact
     3541 cagtttgtat aaacattgcc acctgttcac cacattcata ttctctagga tatttatttt
     3601 tcattaatgc taacaagtct tcatcatcat catcgtcaca ataagttgta ttttcaacca
     3661 agcgatgggc aaataatttt atatgagtta tgaatctata ataatcaata gaatcttggt
     3721 taaactcagt acaatagaaa tcttgaatga ttttctcaat tcccataatt atttcagtga
     3781 ttttatacga ctcttgaaaa ttattttcta aattagcatt aacaaaatgt agcgctatga
     3841 atgcagcttc gtcaattgga agttcaatac ctaactcttt ttttattatt tgtaaagccc
     3901 ttttcccaag ctcaaattct tctttataat atttcgagat ttcccagcgt aggggattcg
     3961 aaataataac tccttcttta taacgttcta tactcgaaga aatatgatcc gttagattta
     4021 tatagataat ctcatcaaaa ttattaccta atgttatttt acctagatta attatttttt
     4081 cggtgatgta caccaactcc aaaggaacgt taataaacat ctctgtaaaa cgggtcatat
     4141 tatctctatt tttgagaaaa aaacttttct caatatcaat tggatttact ttatctccaa
     4201 tttttcttcc aaaagctatt ccccttccaa aaagaagaat atcgatatct tttttacttt
     4261 gcgcaattac ggcattgtgg tttagtattc gttttatgat cataaaattt cccttttaaa
     4321 ataaaaggaa cctacttaaa aacatcaaga aacttcttct gatgtgatta aataggttcc
     4381 tgctcacttg tattagtgat aacatccttt tatttcaatt tttaatggtg acatgaagct
     4441 taaataatta ataactctgt aaccattttc attttaagat atttcaatct atttgtcaag
     4501 tacttgtaga aattttttta ttttgtgtga ttcgaatgtg ataatggcaa cagtctcact
     4561 aaagaaatga aaatcataca tagaaatttt taaaaatttt ctctatcgta aacctgccac
     4621 tagttcagaa actatactag ctgattccaa acgtaatatg gtcatctcat ctaccttccc
     4681 taataatggc attgcatcat accaaacaat agtcttattc accaaaagaa taggcgttac
     4741 tatttttgat tgagtaaaag acactttaat tttctggctc ttcaactggt ctagccatgc
     4801 tttatttgca accgtctctg gtatacatat ctcaatttga ctaatcctaa attcttttag
     4861 aaaattcatc agttttgtct ggtgcacata aggtaaaata agcagacatt cctgtctttc
     4921 ccctgctaag tcctctatca acaccttctc atatctacta tcaacataaa cgaattgttt
     4981 ctcctcaccc tcaatggcac gataatccat ctttcgataa gctacttgtc gtttctgaaa
     5041 catcttttct aaataaggaa catgaatatc cacataatcg aaaatacgca ccaaagactt
     5101 atccttgtag tttctatgaa tccgacctgc atactgaatt aaattatttt tccaagaaaa
     5161 gggtgctgcc aagataagcg tgtccaactg aggtaagtca aaaccttcgc caatgtattt
     5221 tccagtagac aacaaaacaa accctttatc taactgttct aacgtctcca gtaaactcgt
     5281 tctttctcgg actttggttt ttccgctaat aatgtaacag tcatcaacct ctttctcttt
     5341 caataacttt tcaaagacat ctatctgttg aattcgatta actaaaacca agatattccg
     5401 tccttctgcc acttgggcta gaatatcctt gagaatcaac tgattcctcg ctgagtctgt
     5461 agcaatccaa tcactgagct gtataaaatt acttgctttg gtcttttcaa tctccaaatg
     5521 accaaaagaa gtgaatctta attgcaattg ccgtttaaaa tccgtttccc tcttatcagc
     5581 agtatggagt atctcaccaa ttctctgaaa aacaataggc tcatgaccat tcttacgctc
     5641 aggcgtagcc gtcaaaccgt aaagatactt ccctctaaac tgagcaacaa ctttttcaaa
     5701 catcaaggca gagacatgat gacactcatc cacaatcatc atctcatact catccaaaag
     5761 actttgacta ttttccaact taaatagaga ttgaatcata acgacatcaa ccagtttact
     5821 cagccatttc ttagtcccac cgtactgtcc aacatagccg attacctttt cacgacctga
     5881 tgccgtataa cggatagcct cctcctcttc gaaagtcaaa aagcagttta agcgatctag
     5941 ccattggtct aagagttgct tattatggac tagaataatt gtttttgttt tccgttcaga
     6001 gataagagca gcacctaaaa cggtcttccc aaaaccagtc tccgcatgaa gtaaaccatt
     6061 ttctttagaa gtcatatctg acagggctaa ctcttgctca aaagtgagtt ctcccttaaa
     6121 ttccacgcta atagaccttt gtacctttct cctatcttcc acaactacct gcttaaattt
     6181 atcttgcaat ggatacagca aacctcttgg caaccataaa taatgatcgg attctccaaa
     6241 taaatacatt ctctcaggaa tttgataggt tggctgtcgc atagcctgct ttaaataaaa
     6301 ttcgggatta gaaaatgaag ccatattttt caagaaaaac agtgtcttgg gtgtcacaga
     6361 cgatttttca agttggatca tattggataa gacgatcttc aaccccttgt ccaattcttg
     6421 cttgcctaac tcttcttgga ttaacagtgc cactttagca gttgaaaccc tctgaatttc
     6481 ttgtagatac ctccattggt cttcataagg ctgaaactgt tcatccacaa agaccgttcg
     6541 cccttgatgg taagcttctc cttgaaaagg caaggcaatc aaatttccaa atcccccctt
     6601 aggaaggaca tcctgatttg gaaacatgcg atcaaaagaa tcaaaggaca gttgcatact
     6661 ttcctgcatt gccagttcta tcagtttctt tccaaacaag cgagcctctc gactcggaat
     6721 cgcttcctca aagaagaacc aaatatggag tccgtgaccc gaacgagaaa tctctaaatg
     6781 ggcttccatc tggcgttccc tggctattct tcgaatggtt aaaccagctt ctttccaatc
     6841 tccttcatca aaatccagta ccaaaaaatg acagctatca tctaagtgca taggaaagat
     6901 accgatagct gtctccccac gaaaatgaga tttcaaaacg gagttcgtca atgtctggaa
     6961 actccgtttt tcaggtggca actgcttcca accataatca taggaaggaa aatactgaat
     7021 tttcccttgt tcattgataa aattcttagc ataaacatca taacgtccag caaacacgga
     7081 ggtaaacaat tgtaattttt cttgcgtcgt caagtgacta ctttgaagtt ggaacatctc
     7141 ctcgaaccga gagcgttcca taacaaactg actcttgtct ttaagacgtt tacacaagaa
     7201 aaactcacta tccccatcaa aagaagaaaa gacatcaagc acttctacca caattccatc
     7261 caaagacaca aaaacagcca taagagtcac ctccttgatt cctataggct gattataaca
     7321 agaatagctg aaattgtaca cgaaaataaa atccgaatag cactcatttt gtatgcgact
     7381 aatagtccat ctcgctccgg aatgtacgag gtaaatagag tttaaacgag cagtctataa
     7441 aattcaaaaa acgcatatta ccaaggttgt tttgaactac accccaaaag ttagacagaa
     7501 aaaatctaac tttttggggt gtttttatta tgaaattaac ttatgatgat aaagttcaga
     7561 tctatgaact tagaaaacaa ggatatatct tagagaagct ttcaaataaa tttgggataa
     7621 ataattctaa tcttaggtac atgattaaat tgattgatcg ttacggaata gagttcgtca
     7681 aaaaaggaaa aaatcgttac tattctcctg att
//
LOCUS       DAVLHM010000070         7700 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLHM010000070 DAVLHM010000000
VERSION     DAVLHM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.070"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(762..1982)
                     /gene="divIB"
                     /locus_tag="VXE45_001956"
     CDS             complement(762..1982)
                     /gene="divIB"
                     /locus_tag="VXE45_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0789941.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            complement(1992..3050)
                     /locus_tag="VXE45_001957"
     CDS             complement(1992..3050)
                     /locus_tag="VXE45_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0789942.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(3054..4406)
                     /locus_tag="VXE45_001958"
     CDS             complement(3054..4406)
                     /locus_tag="VXE45_001958"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0789943.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(4510..5151)
                     /locus_tag="VXE45_001959"
     CDS             complement(4510..5151)
                     /locus_tag="VXE45_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789944.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(5153..7174)
                     /locus_tag="VXE45_001960"
     CDS             complement(5153..7174)
                     /locus_tag="VXE45_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0789945.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(7245..7544)
                     /locus_tag="VXE45_001961"
                     /pseudo
     CDS             complement(7245..7544)
                     /locus_tag="VXE45_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
BASE COUNT         2301 a         1684 c         1320 g         2395 t
ORIGIN      
        1 taaataatat ttcttcccta ctaacactaa taagtccgat atggtaaatt cttgacctat
       61 tagttgctct aaccattttt ttcctgtttc ccaactaata catgtttctt actggatggt
      121 atatatagat gatactgtcc ctcataagga gtaggtaata tcttaatctt atcaacaatt
      181 ctcataacaa acctaacctt taataaataa aagaggggct aagtaaaaca tactctagtc
      241 cctcagtccg caatcaataa aataatgact aattctatta atctcttgct gcaagactaa
      301 tacggaaaat tcaaatgact gtctaaattg aaaaagcttg atattagtaa gtgaacaaac
      361 ttcaacaacc agcaagagca aggattgcta aaccaaatcc gatacctgtt gcaagtccag
      421 ctgaaaaatc actaactggt actgaaattt cttcaatttc ctcaaataaa aagttatctt
      481 gcatgattat cactccctat ctttttaaca acaggctact ccaattaaga gaactacccc
      541 agttccaagt aaaactcccc cccaaaattc accatctgta ggggctacga tttcttcaat
      601 ttcttcaaat aagaatactt catctgacat atgtgttacc ttcttcataa aaaatttttt
      661 tgtaatcgat tacattgcaa atgtaacata aagaaaaaca gatgtcaaat attaaacgta
      721 aaaacatggc aactaaagag ctataggaga aaaggtaaaa cctagcgacg cgatgagcgc
      781 tgggtcgttt ggtttcgatt gctctcttcc tcttgttttt tctgttcttc ttctaaacgt
      841 ttacgttcct cttcctgcct tttctcagct tcttcggcct cttttttagc tttttcttct
      901 gcttccataa tcaatttatc cgctacagtg tagctgtaga ctccagcttc catgtcaatc
      961 acactcggtt ctgacaattg tggcttaatc ttactgtaat atggcagttt cttactcatt
     1021 tcagatagag gaaccaagac ttcgtccgaa tcattcatgg tcaatcgaat taaatcggat
     1081 gtcaccttgc ttggggctaa ttccaccttt tggatagccg ccttgagttc tgggctaatt
     1141 tgagcaagtt ctgagacaaa aaccttgatt tgttcactat cattaaagag aactgataaa
     1201 taagtttctg gtaaactgtt cagactcaca gaactagtct caagctgacc actggaaaga
     1261 ataggataat gattttcacc agaaatatag taggccacaa tatcatattc cttgacctta
     1321 atagtgaact tagttggaaa ttgatagaca agttgagctg attcaaccca atagttagac
     1381 ttaatctgct tttcatattt tgccttgtct agcagaaggt taatcgtata atccgaatcc
     1441 tgaatgcctg aagcctgtcg aatatcatca gctgtagttt gcaccgttcc ctcaacacga
     1501 atatctttca tggtcgcata aggactgagc aagtaggcag agacaatcaa taaaagcaga
     1561 cttggaaata aaatcgtgaa ggctcgcaag atatggatac caggaatctt tgctttggct
     1621 ggtttttcct ttgtagcctt tttagcaagc tttttatcct gttcctcctt ctctttagac
     1681 tctggttctt ctttctcttc tttctctttg tcagcctctg aggatgctac tttttcttca
     1741 gactcttcct tagctgattc tgaatctttc tggtctgttt cactctcctg gtcctgttta
     1801 tcctctgact tctcagattc ttctcccatt cgagcttgtc tttccttttc cttctcctca
     1861 gctagagccg cctcttcttc agccttcttt tttagatatt cttggtttcg tttctgccat
     1921 tctgataact ctttcaattc ttcgagggtt tctttgtcct catttttctt atcttttgac
     1981 atttactttc cttatgataa atcttttttc aacaattgat aaaaatctgc tagagatttc
     2041 aattccttag aagctttcat cttagcttgg taatcttcct tgtgacttag taagtgagaa
     2101 agcttctctt ccaaactatc caaggtcaaa tcgctttctt gaaggtcttc tgcatagcct
     2161 ttcttaacaa agtaagctgc attttcaatc tggtcaccac gactagcttc acgaccaagc
     2221 ggcacaatga catgcaattt tgctatcgcc aagagctcaa aaatcgtatt ggcaccacca
     2281 cgtgtcacaa caatatcagc caattccatc aagggttgat agagatcggt cacatagtca
     2341 acacgaaaaa gattttggct caactcattc aggctagaat ctccagttag attgataata
     2401 ttgtagcgct ctgttagttc ttttttatgg tctgtcacca attggttaaa gacacgagca
     2461 cctgcagaac cgccaacaaa caatacagtc ggcaatttat gattaaagtg gctttgaata
     2521 tccaccaatt catctggttc tggatttttt tgatctgaaa ccttggtcac tgctcccaca
     2581 tgctcaacct tagccaaact cgaagcttgt tcaaaggttg aatacatctt agtcgcaaat
     2641 ttataggcga ttttattggc caagcccata gacaggtcag attcgtgaat aaagacaggc
     2701 actcctgaca cacgcgcagc gataacaggc ggtactgaga caaagccccc ctttgaaaaa
     2761 agggtctgtg gacgaagtcg caacatgata aagagcgatt ggacgattcc ccagccaact
     2821 ttgaagacgt ccagcatatt ttgccaagag aaatagcgac gcaatttccc agtcgcaatg
     2881 gagtggaaag tgacatccaa acctgactta aggatttctt ggtgttcgat accacgcttg
     2941 tccccgatat agtggacttc ccaaccatct tcgatgaact tgggcattaa caaaagattg
     3001 agggtaacgt gtccaaccgt ccccccacct gtaaagacaa tttttttcat attttattct
     3061 tttaactccg ctactgtgtc gataaagagg tcgccacgta cttcaaagtt agcatacata
     3121 tcccagctgg cattggcagg actaagaaga accacatctc cttgagtcgc aagctcatag
     3181 gccttgcggg tcgcatctgc aatatctgtc gcctccacat aagcgacacc agccttgtct
     3241 gctgcccgtt tgacacgttc tgcagattga cccaggatga ccatcttctt gagtccagta
     3301 atatctggca ccaattcgtc aaactcattg ccacggtcca aaccacctgc aatcaagacg
     3361 accttgctgt tgtcaaatcc tgacaaggct ttttgagtag ccaagatatt agttgattta
     3421 ctgtcgttat agaatttaac acccttgatg tcatccacaa actggagacg gtgtttgaca
     3481 ccaccgaagg ctgaaagagt ttccttgatg gtttgattgt ccacaccacg aagcttggct
     3541 acagcaatag tcgcaagggc attttccaca ttgtggctac ctggaacacc gatttcattc
     3601 gctgccatga ctacttcacc acggaagtag agttgaccat cttccagata agctccatca
     3661 accttttcaa gtgttgaaaa tggtacaaca gtggcttctg tcttggaagt caagtctttt
     3721 gccaagtctt gattaaagtt caagacaagg aaatcagctg ctgtcatctt gttctggata
     3781 ttccacttgg ctgctacata ttcctcaaat aatccatgat aatcgatatg agttggcata
     3841 aggttagtaa taaccgcaat ctctggatga aattcttgaa cacccatgag ttggaaagaa
     3901 gaaagttcca taacaagcgt gtccttgtcc gacgcagttt gggccacttg actagctgga
     3961 tagccgatat tccctgataa aagaccatgt tgcccagcag cagtcaaaac ttccccaatc
     4021 atagtcgttg tggttgtctt accgttcgat cctgtgatac caataatcgg tgcttctgaa
     4081 atcaaataag ccaattccac ctcagtcaag actggaattc ccttggccaa agccttttca
     4141 atcatgggat tgttgtaggg gatacctgga tttttcacca taagggcaaa ctcttcatcc
     4201 aagagttcca aaggatggcc acctgtaatg accttgatcc cttcttccag caaactttgg
     4261 gcagctggat tgtcctcgaa tggtttcccg tcatttactg tcactatggc gcctagctta
     4321 tccaacaaac gagctgcaga ttcaccagac ttggccaaac ctaaaacaag aactttctta
     4381 tttttaaatt gatctattac tttcatgtct cgaactccat ttctactcct actattttac
     4441 catttttatg gaaataaaaa agccacaaag tgtgtttgtg actctttctt ctaactgaat
     4501 cttaccatat tatctatgtg ataaatcggt aactcgaatg acctgatcca cttgctccca
     4561 aatcagagga ttgtgggtcg caataataat ggtccgattc ggatttttta aagattctag
     4621 gatggaaagt aattcctcag agtttttggg gtctaaggaa gcggttggtt catctgcaag
     4681 aatcaaaggc ggatccttta aaattatctt cgctaatgca acacgttgtg cttctcctcc
     4741 tgataactca aatataggtt gcttcaaatc caaataagag aggtttacac ggtttagagc
     4801 ttgtttcatc aaagagattt tctctttttc cttcaacttt ttaccaacta aacccagatt
     4861 gagattctct ttgacggttt ggctttcaat taagccaaaa tcttgaaata agtatcccaa
     4921 gtaatctcta aagaaaacag aaggcttgat gtccttaaga gaagtgccat catagatgat
     4981 ttgccctttg tcatatggct ctaatcgtcc aatcatattc aagagtgttg tcttaccaca
     5041 gccacttgta ccgattaagg cataaatttt cccaccttca aaatgaagat ttgtatctga
     5101 aaatagctga cggcttccaa attttttaga tatattcttt agttcaatca tcctattttc
     5161 ctttcataat tgtcatagaa acacgagatt ctttctgcgc ttgacggtaa agcgtcagaa
     5221 ctgcactagc tagaaagact aataaagtga gcaagccaat caccaagtct cgactgctta
     5281 aaataaagag actagcacca aatacaaaac tggcaaattg actaaccata tactgagcat
     5341 gtgtttcaaa aaatcgtaaa cctgaaattc gtttaatcaa aatatctcgg cggaattgct
     5401 cgaaatatag aagattgaca gaataaaata gtaacaagga actagctatc cccacaatag
     5461 ctcctaagat taaagttgct gtttcagttt gaacttcatt ataacgagtt agataaacac
     5521 ttcttccttc tttaagatag gatacttgct cataaattcc agctttcttc aagagttcta
     5581 gcccactctc atatcctttg ataaagagtt gttttccagc attgatagac caactagata
     5641 aggatataaa actatcacct gtagaagtcg gcgtgaatac aactaaaatc ggatcaatca
     5701 aatactgagt ggatacggga ttctcaccgt tattataaac aaaccgcttt tctcccattg
     5761 aaagataact aacgtgcgct ttcatctcat aatccaaagg agcacttgcc tcctcaccag
     5821 attttccata ataactcaat ctttcttcaa aaactttctt aagttctgct tctcgagagc
     5881 gcaaatgttc tgggagcaag aggataaact cacctttttg gagatgggct aacttctgtt
     5941 tggtctcagc atctaccacg accttttcct tgtccaaata actgggacta acatagagcg
     6001 tattagcatc tggactatag gtatccagtg tctctccctg ttcatttttt ccttgtggat
     6061 tggcaaaatg gagcagatta tcctttacat aaagagcttg ttcttcttcg attgcttcct
     6121 tggcaaaggc ataccacttg ctctgatttt ctgtatcttt tcctctatca cctaagccaa
     6181 aagaaatttg ataatagtct gctctatcct gccatgcttg ttttgaaatt tcaagttctt
     6241 tcaatcgttg gtaagacgtc aaacctgtct taacagcgta tcctactgta aagacagcaa
     6301 ccaactgaca caatagggtt aaaatcatca ggcgtttaag gggtaatctc cccttaataa
     6361 cgggaactaa tgctttgtaa ttcaaactca ttagataaag aagcattagt aaaattgaaa
     6421 tcgccaataa aaacaacaga tagaaactaa tcccaaaacc ataggtggct aacaagatag
     6481 gataaaacaa accttgacta aaaagaacga ctcccccacc taggaaggaa aggagggctg
     6541 atagaaggag ccatttgata tcagtagata aagaatgccc catgatggat aagagagtct
     6601 gaccagaaaa gagttttata cctgctgctc tcatttcctt aatccgagtg ataatcacta
     6661 aagcaaagaa agataaacca aatattgcta aactaattaa aataagggga tttagtaata
     6721 ttcgaaaagc aagaaaatag ggcggtatct ttcggtcagc acttgcttta taacccaaat
     6781 ctcctaattt atcggcaagc ttttctttcg tcaaggagcc tgacaaaagg agataactat
     6841 ttagcggatc actacgttca cgactttctt ggctagcttc ttggaattct tttggtaaag
     6901 ttccctgacc ataagttgca taagtaaagt gagtcgtccc atccttactc ggctctacaa
     6961 ttcttctagc tattaaactc tgttctgagt ttgcaaaatt ctccaattcc tgttcaaata
     7021 cctcacgcgt cggttcctga gtatcttttt tgacacgaag taaagaaacg gaatcatagc
     7081 ttgcatataa atattgtggc gcacgtaaga caataatcca agcaaggaag aagctgagaa
     7141 aaaaagttga taataatatg aatagtttct tcatagtaga ctccttgtaa acaaaattcc
     7201 ccctgtaatt tcttacaagg ggaacgattt aaatcaatga acgattagtc ataatcacag
     7261 taaaatgcta cttgttctcc ccatttagtc caaatccatg cataggaggt ttttccagca
     7321 ggagcttctc ctttatcaga atgaccatcc catctgctca cgatggatga ataatgatat
     7381 tttttaccat gatagtaatt tgaaaaagcc taaccacctc ctgaaccttc tccatatgtc
     7441 catactcctc catctggata ttgtacagca gctgatgcag ctcccaataa tgtaaaattt
     7501 gaaataagag ctagagcaag taatctatgt tttttcgttt tcattttatt ttttctttca
     7561 aaaaaatcac accttgagca acaatgcaac aaaataaatc ctcctctctc ttttgttgaa
     7621 atcgctttct tatgtgataa gaataacatt tttattattt gttgtcaagg aaaaaatcga
     7681 attttttaga tgttttacta
//
LOCUS       DAVLHM010000071         7645 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLHM010000071 DAVLHM010000000
VERSION     DAVLHM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.071"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..846)
                     /locus_tag="VXE45_001962"
     CDS             complement(1..846)
                     /locus_tag="VXE45_001962"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0789946.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKACAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1102..2129
                     /locus_tag="VXE45_001963"
                     /pseudo
     CDS             1102..2129
                     /locus_tag="VXE45_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(2430..4319)
                     /locus_tag="VXE45_001964"
     CDS             complement(2430..4319)
                     /locus_tag="VXE45_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0789947.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGTEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLLGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4457..6022
                     /locus_tag="VXE45_001965"
     CDS             4457..6022
                     /locus_tag="VXE45_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0789948.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYANAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            6022..6762
                     /locus_tag="VXE45_001966"
     CDS             6022..6762
                     /locus_tag="VXE45_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0789949.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6871..7086)
                     /locus_tag="VXE45_001967"
     CDS             complement(6871..7086)
                     /locus_tag="VXE45_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789950.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         2417 a         1703 c         1355 g         2170 t
ORIGIN      
        1 ttatacaaat aaacggacaa aactgtaaag tagcaaaaca ctaccaagca cgatacggta
       61 tttaccaaaa agggtgaagt cgtgtttttt cacatagctg gtcaagaagc gaatagccac
      121 catgctgacc gcaaaagcta ctcccatcgc gaccaagagc aaaaacaatt gcccaaagct
      181 caagagttct ccggctttca caaatttgaa aatctttaag gcactagctc caaacataac
      241 gggaatccca agatagaagg taaattctgt cacaactgaa cgactggttc catttaacaa
      301 accaccgaca atcgttgcac ctgaacggct agtccctggt aaaagagcaa gaacttggaa
      361 gagtccgata tagaaagcgg tcgtataagg aagcttgtcc aactctgtta cacttggctc
      421 gatagcacac gctttattgc gcttttccaa atagatgaag gcaaccccgt agataatcaa
      481 catgagagca actgaaacca tgttatggaa gtgggtatca aaccaatcat caaatttaaa
      541 gacaccaagt aaaggtaaag tagcaatcaa gaccttcaac catagtctcc aagtcttacg
      601 aacttcctgt ttgtccttag tcggtttaaa aggattgagc ttgttaaaat aaatcaccat
      661 aactgctaaa atagcaccaa gctgaatcac gacattaaac atggacataa aggcttcatt
      721 ttgattttgg tattggataa actcctctgc taaaatcaag tgacctgtac tggaaatcgg
      781 caaccattcc gtaattcctt caacaatccc gaagaagata gattttaaaa tttcaataag
      841 atacatatat ttctccttat attatattta acgcagttag ctactgccaa agcccaagtg
      901 gtatacttgg aataagccac tgtggattag ttcatttcct ccaatcgctt gacgatttcc
      961 gaaaggatct aaccacagct ttttgtttca attggtaatg agtttgataa cgcatagacg
     1021 ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta gacttgaaat
     1081 actatatctg gaggtactcc catgctttat gtgggcattg atgtcgctaa aaataaacac
     1141 gatgttacag ccttgaatgt tcgaggaaaa ctgttcttaa accactcact ttttcaaata
     1201 ataaagctgg ttttgaacta ttagatctgt ctcttcgaca gctcaaccaa gactgtctca
     1261 tcgctcttga agataccgga cattatgcct ttaatctact gaacttcctg catgaacaag
     1321 gatataaagt ttacacctac actcctttgc tcatcaagga atttgccaaa tcattatcac
     1381 ttcgcaagac taaaacggat aagaaagacg ctcatggcat cgctcttaaa cttctttctg
     1441 accccaatcg tgaacaattt caacacgata atcggcaagt agaactaaaa atactggcta
     1501 gacatattca tcgtctcaag aaaaaacagt ctgattggaa agtacaatac actcgttgtc
     1561 ttgatatcat ctttcctgag ttggataaaa tcgttggaaa gcattcagaa tatacctacc
     1621 aactcttgac atgctaccct aatcctcaga aaaggcttga ggcaggattt gataagctga
     1681 tagaaattaa gcgattgacc gcttctaaaa ttcaggatat cctctcagtc gcacctcgtt
     1741 ctatcggaac aacatctcct gctcgtgaat tcgaaatcat cgaaaacatc aaacattaca
     1801 agaggctcat tgacaaggcg gaaaaatgtg tcaatgactt gatggctgag ttcaactcgg
     1861 tcatcacgac ggttactggg attgggaatc gtttaggggc ggtcatttta gccgagattc
     1921 aaaatattca tgcctttgat aatcctgctc aattacaagc tttcgctgga ctggattctt
     1981 ctatttatca gtcaggtcag attgatttag ctggaagaat ggtcaaacgg ggttctcctc
     2041 atctgcggtg ggcactcata caagctgcca aagcatgcgc tcgcttttca cctgctttta
     2101 aggcctatct taagactaag ttagaataag aaaaacatta caatgtagcc atcatccacc
     2161 ttgcaaaaaa acttatccga accctgtttt atatcctaaa aaagagctgc catttgacga
     2221 acaaaaagtg atgtaatttc tgaaatcaac acaggattac ctttgaaaaa atggactttt
     2281 tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc atcaaattga aataagaaat
     2341 agtttagata aaattattga cttttcttat agtttgtctt tcttctatct tccattatat
     2401 catacttttt cagtctatgg tagctctctt taaaaggctc cgatactgcc gccacctccg
     2461 cctccagaga agccaccgcc agaacttcca cttccagaag atacggagta ggtacttgct
     2521 gtatttgcga cactagcata atggctcatt tgcgcgcttg aatgataaaa catactgtgc
     2581 cagccataag ctacatagag attgatatct ggattttcaa cttgaatctg atgaaccttc
     2641 atcaaatgac taaccttgtc cgcatagcca agtaaggttg catagaccaa gagacgattc
     2701 caaacaacaa tactttccaa ttcagcctta tccagtcgtg caatctcacg taacatattt
     2761 tcaaaactgg tccagagata gtagacctca gctcccgctt catttagaac accatcacga
     2821 ttatctagtc gaagcttcca ataatagaaa acagacaaaa ctaaccctag aaaaccaagt
     2881 attggcaaag ggaggtaaag atagccatga acgtctaaac tgtacaagaa caaaccaaat
     2941 ccgataaata ggggcaggat agtcaaggca cccataccca cttgcaaggc cttttcccca
     3001 ccagttaaag gacgataata atctgggagc ccccagaagg aaactcgttt tctcactcct
     3061 tcttgcatct ggttcaatac ctcttcaaaa gaagatttga gttgaagccc tcttgcttga
     3121 atccgttttt catcagaaac tttggctcta cgataaagac tatcagatac cttgtaatcc
     3181 gcaaacaaat tggaaagagt ttcttctttt ttacctgaaa aggctagatt tagacagtct
     3241 ctctcaaagc ttgacaaacc atcttctttt actagcctca aaccaactgc atctccttct
     3301 gaaatgatag agacattccc acggtctatc acatctagca aggtagcttg aataagttga
     3361 tcaaaggtga attttccagc tcccttgacc aagggactca cttcctccaa ggaggtcgag
     3421 tagactgctt ctgataaaac cataggctct aattccattg gtggttcata gagacgatga
     3481 tttttggcat atttgactga aggagtggtc tttcttctat aaataaaata gaagcagaca
     3541 ctcaataaca aggagatgga aaggatcgaa gggaggaccc aagtaagtag ttgtttactt
     3601 tgctcttttt ctctaacaat cgagtcttct atcttattaa actcttctaa tcgattccct
     3661 ttcaatccct gatccctagc gctagcaaaa tcggtccgag gccaataggc atgcaactca
     3721 actccacgct tagccggaag attgtctaaa cggatagtat aatcaaggtt actcttttca
     3781 atcgttccct ctctaaaaag tttccctgta tggaaaaaga gtttttcagt ccccttgtct
     3841 ccccttacat gaaattcaaa cttttcaata gactctgaac tatctgtcag aggttgccaa
     3901 tttaattcag cgatatcatc ataaaggaaa agtaaatttt ttaagttcca gacgaggtca
     3961 acttcaacta tgtcgccctc ctgacctgga ttatagactc tcacagtata accatccgct
     4021 tcttctgtta cttcgctagt cacatctgct agttctgcac cgtttttcgc ggcctgaatc
     4081 tttggatgag ggtcaatgtc aaacccgcta ggcatcttac cagcacgtcc aagtcccacg
     4141 atttggccct taaagtcctc ctcaaactgg taaactatct tctgtctaaa ctctgccgta
     4201 ttatctgcat gaatatacaa atccccttga taagagttta tcttgaaatc aatggcaaaa
     4261 acagagagtg gaagaaggca aaacaagcct aacaccagta agaaaaaagt ttttttcatc
     4321 aactaagccc cctttttatc tttcttatca ttatagcatt ttttcgtaag taaaggctta
     4381 cttatgttga aaaattacgc atttttcgat aaaataggag acagttattt tttaatagat
     4441 cagaatagga gaaatcatga gaaaaatata cttatctatt ttcacaagtc tcttgctgat
     4501 gctaggactt gtcaatgttg ctcaagccga tgaatattta cgcatcggga tggaagcagc
     4561 atatgctccc tttaactgga cccaggatga tgatagcaac ggagctgtca aaatcgatgg
     4621 gaccaatcag tatgccaacg gatacgatgt tcaaatcgcc aagaaaatcg ctaaggactt
     4681 aggtaaagaa cctttggttg ttaaaaccaa gtgggaaggt ctagtccctg cccttacttc
     4741 tggtaagatt gacatgatta tcgcaggtat gagtccaact gcagaacgca aacaagaaat
     4801 tgccttttcg agcagttact acactagcga accagttcta ctggtcaaaa aagattctgc
     4861 ctatgcaaat gctaaatctt tggatgactt taatggtgcg aaaatcactt ctcaacaagg
     4921 tgtctacctt tatgacttga ttgcacaaat cacaggtgct aaaaaagaaa cagccatggg
     4981 agacttcgct caaatgcgcc aagctcttga ggctggtgtc atcgacgcct atgtttctga
     5041 acgcccagaa gctctgactg ccgaagccgc taactctaag ttcaagatgg tccaagtaga
     5101 accaggtttc aaaactgggg aagaagatac agctatcgcc attggacttc gtaaagatga
     5161 cactcgtatt agccaaatca atgccagcat tgaaaccatt tcaaaggacg accaagttgc
     5221 cctgatggat cgtatgatca aggaacaacc tgccgaagct acaacaactg aagagactag
     5281 cagtagtttc tttagccaag ttgctaaaat tctttctgaa aactggcaac aactcttgcg
     5341 tggtgctggt atcactcttt taatctctat cgtcggaacc atcacaggtc tcattattgg
     5401 acttgccatt ggtgttttcc gtactgctcc tctctctgaa aacaaagcca tttacggcct
     5461 acaaaaacta gtcggctgga ttctcaacgt ctacattgaa attttccgtg gtacgccaat
     5521 gattgttcaa tcgatggtta tctactatgg aactgcccaa gctttcggga tcaaccttga
     5581 ccgtacactg gctgctatct tcatcgtttc aatcaatacc ggtgcctaca tgactgaaat
     5641 cgtccgtggt ggtatcctag cagttgacaa gggacaattt gaagctgcga ctgctcttgg
     5701 tatgacccat aaccagacca tgcgtaagat tgtcctacct caggtagtcc gtaacatcct
     5761 acctgcaact ggtaatgaat ttgtcatcaa tatcaaagat acatctgtat tgaacgttat
     5821 ctctgttgtc gaactttatt tctcaggaaa taccgtggca acacaaacct atcaatactt
     5881 ccagacattt acaatcatcg ccgtgattta ctttgtcctc accttcaccg taacacgtat
     5941 cctacgattt atcgagcgcc gaatggacat ggatacctat actacaggtg ctaaccaaat
     6001 gcaaacggag gatttgaaat aatgacacaa gcaatccttg aaattaaaca cctcaaaaaa
     6061 tcctatggac aaaacgaagt gctaaaagac atttcactca ctgtccacaa gggagaggtc
     6121 atctctatca tcggaagctc tggaagcgga aaatcgacct tcctacgctc cattaaccta
     6181 cttgaaacac caactgatgg acaaatcctt tatcatggac aaaacgtcct cgaaaaaggc
     6241 tatgacctca cgcaataccg tgaaaagttg gggatggttt tccaatcctt taacctcttt
     6301 gaaaatctca atgttcttga aaacacaatc gtcgctcaga caactgtcct aaaacgcgaa
     6361 cgcacagaag ctgaaaagat tgccaaagaa aacctggaaa aggtcggcat gggagaacgc
     6421 tactggcaag ccaaaccaaa acaactctca ggtggtcaaa aacaacgtgt ggccatcgct
     6481 cgtgccctct ccatgaatcc ggacgctatt ctctttgatg aaccaacatc agctctcgat
     6541 ccagaaatgg ttggagaagt cctcaaaatc atgcaggacc tggctcagga aggcttgacc
     6601 atgattgtcg taacccatga aatggaattt gcccgtgatg tctctcaccg tgttatcttt
     6661 atggataagg gcgtgatcgc tgaagaaggt aaaccagaag acctcttcac caatcctaaa
     6721 gaagaccgaa caaaagagtt ccttcaacgc tatctcaaat aaaaagaaaa ggctgcatca
     6781 accgtgcagt ctttttgctg tcctcaaaat gaaaaggcag attctctatc tctactactt
     6841 gaaggtcaag aatccgccgt tatccaaaga ttaatcttca aatttttcat aatttttttc
     6901 atagaaatca attaggccta gggctgtttc aaatgaaata ttttttactt ttgcacgacc
     6961 ctgcgccaga gcaatgatag acatttcacg cgcattcgtt tctttagaga tacggtagcc
     7021 tgtgattttc ttatcacgaa cccagccaac aactgattct actttttcaa agtttgactt
     7081 agccatgttt ttctcctatt ttcttcttta taatatttaa ttgtatacgt ttttactact
     7141 tttgtcaata aaaaaacatg tattcaacga aaataattag ttcagaattt tagcttcaga
     7201 attttcttac ttcctttttg aatccgataa tatataggtt ttactagtct ctacaccata
     7261 aatatttgct aataaaaata ctgtattatt accctcttaa ggtgcgaaat tattcaagtt
     7321 cttaaaaaat gcttctctat ttccgtaaga tagcttattt cttcgattta agaactgaag
     7381 atgatagttc taacctttag aaatccaagc cttcactagc tcaaaaactc ctatctttct
     7441 tcctcaataa atcatctgag agataggtat tccttatgtc cttcaaattc atcactcctt
     7501 tggatattga ggtgctagcc tagaagcaga cacccgatta tctaaaccat ccttaataaa
     7561 gatgacaaga cagataagct cagttaatta cttatatatc tttttaatat ggtatatttg
     7621 tcaacaaaaa gaaatcaaat catac
//
LOCUS       DAVLHM010000072         6852 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLHM010000072 DAVLHM010000000
VERSION     DAVLHM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.072"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..752)
                     /locus_tag="VXE45_001968"
     CDS             complement(<1..752)
                     /locus_tag="VXE45_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0789951.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNTPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQI
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHAQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(749..2074)
                     /locus_tag="VXE45_001969"
     CDS             complement(749..2074)
                     /locus_tag="VXE45_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0789952.1"
                     /translation="MDFFLLVDLILYFLIISHSYRLICKDQINRKELFFFGAYTLLTE
                     IVLDFPFYLLYLDGLGIATFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYYGLFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKRKFE"
     gene            complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VXE45_001970"
     CDS             complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VXE45_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0789953.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNIFNFFNFFR
                     RR"
     gene            complement(2392..2465)
                     /locus_tag="VXE45_001971"
     tRNA            complement(2392..2465)
                     /locus_tag="VXE45_001971"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2429..2431),aa:Arg,seq:tct)
     gene            complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VXE45_001972"
     CDS             complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VXE45_001972"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0789954.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3171..4352
                     /locus_tag="VXE45_001973"
     CDS             3171..4352
                     /locus_tag="VXE45_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0789955.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            4410..5168
                     /locus_tag="VXE45_001974"
     CDS             4410..5168
                     /locus_tag="VXE45_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0789956.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIYFSNQEEYSRIINSLK"
     gene            5381..6742
                     /gene="dnaA"
                     /locus_tag="VXE45_001975"
     CDS             5381..6742
                     /gene="dnaA"
                     /locus_tag="VXE45_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0789957.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
BASE COUNT         2375 a         1223 c         1087 g         2167 t
ORIGIN      
        1 cacttttgag attttttctc taaaatatct tttaattttc taatttttaa tcttgaaata
       61 ggacaacgat ggtcttcata gaaaacaatt tctaagtttt ttcgatcaat ttctctgata
      121 ttgcctatat ttaccaaaaa tgacttgtga ggagaataaa atcgctgagc atgtttgtcc
      181 ttttcctgaa tatctgtcat ggtaccataa aactcttttg caaaattctt accaataatg
      241 cgcaatttat gagagactcc tgtcgtttca atatacaaaa tatcatggta aggaattttt
      301 aaatcatttc ccttgtaatt gtagtcgaaa taatctacaa catcttcatt ttcaagtaac
      361 atactcttcg tgtagaagat attttgctca attcgcttct taaacatctc atcgttgata
      421 tccttatcaa caaaatctag ggctgatatc tggtatttat aggtcagagt cgcaaactct
      481 gatcgactgg tgataaagac gataatagcg taaggattgt aatgacgaat gagttgagca
      541 acttcaaatc cctttttctc aattccatga atatcgatat ctaggaaata aagttgattt
      601 acttcatcat tttcaatgta ttcttcaaat tcacggactt ttcccgttgt cttgtatgat
      661 attggagtat tcgattcttt cgaaatttca tccaatattc tctctagtct cacttgatgt
      721 tcaataacat cttctaaaat taaaactttc attcaaattt cctcttaaat ctaatgattt
      781 gtctaaatgt actgccttcc atctctgttt ctaaaataat gttgttgtac ttatctagta
      841 gttctttcac attatttaat ccgactccgc gatttcttcc cttagtggag aatcctaagg
      901 caaatagatc tcctgaagga gtcatcgtca ttttacatga attctgaatc acaataactg
      961 tttcagtttc catcttaata actgctactt ccatctgctt tttatagcta tcagccgatc
     1021 cttcgacagc attgttcaat aaaacgctca tgatacgcac taaatccaat agttcaattg
     1081 gaagcttggt aatcgtatct tttacttcca gtgtaaactc tacaccatta tttcgagcat
     1141 agacaattga ctgagcaacc aaacttcgta aagctgaatc ttctatgttg ttcaaatcaa
     1201 agtaagtgta cttatctgaa cgtagtttat gatttgcttt gaccaaaact tcattgtaaa
     1261 ctctgtcaat ttcctgtaaa ttaccactgt caattgccat ctgcatgctg acaagcattc
     1321 cagcataatc atgtcgaaaa ccacggattt cattatacag accgacaatt tcatctgtgt
     1381 aattctgtaa atgtttctgt tcaaatttct tctgcttcaa agcaatctct ttctccattt
     1441 gaactttatg agaattcatt gcaaagaagg tcaaaaggag agagataaag acaatagatg
     1501 acaaaatact tccaaaacta ttcaaatgtt taatcgtact taccatatct gaaacgaaag
     1561 atacaatatg tagcaatagt aaagcaaaaa atactttttt caagaaagga taaaggtagt
     1621 ccttgtcaaa ataggctagt tccaaatgga aataataaat gatttttaat gtaacaaaat
     1681 aggtcaacac cgtcacaacg aaaaagaata ggccataata ctgtaaaaca aaattgtctc
     1741 ctgttataga agagaaagtt acggacagaa agttatgagt gctctcatat aaaagagata
     1801 gtagtaaact tagaaatagt cctctatccc tctcatactg tttcatccat cgaaaatagg
     1861 aatataggcc caaaggaaat aaaaatgttg caatccctaa cccatctaaa tatagaagat
     1921 agaagggaaa atcaagtact atttctgtta gtaatgtata agcaccaaaa aagaataatt
     1981 cttttctatt tatttgatct ttacaaatta aacggtaact atgactaata attaaaaaat
     2041 ataatatcaa atctactaat aagaaaaaat ccattctgct actcctttat cttcttctaa
     2101 agaaattaaa gaaattaaag atattaaagg acttttcatt cattttcctc atctccccac
     2161 cttgaatatt ttgcaagtct ttttccttca aagctacaaa ctgttccaat ttaactgtgt
     2221 ttttcataat aaaatctcct aaaatgtttt ttcttgtaag ctaacttaca aaaaccatta
     2281 tacaaaatgg aatttcgttt tagataaaat tctctcaact gtcatttttt tctcccaaag
     2341 tgtacttttt taagaaaaaa gccgggaaaa ttcccagctt tgctattata ttgatcccag
     2401 caggattcga acctgcgacc gttcgcttag aaggcgaatg ctctatccag ctgagctatg
     2461 agacctaaca caattattct accaaaaatt caattaaaag tcaattttct atttatggta
     2521 ggggaatccc tgctgaatcg taaaagcgcg atagatttgt tcaacaagaa ctagtctcat
     2581 taactgatga ggcaaggtta ggcgaccaaa actgacagaa agattggctc tattttttac
     2641 agatgatgat aatcctaaac ttcccccaat aataaaagta agagtagaaa atccttttat
     2701 agaagtttct tctaactgct tactaaattc ttctgagaag aaagttttcc cttcaatggc
     2761 taacacaata acgaaatcac ggtcagcaat ttttgataaa attctctgac cttctatttc
     2821 taaaatcttt tgattttctg attcactggc cttatctggt gttttttcat ctgataactc
     2881 aatcatttca aacttagcaa atctagaaat tcgttttgaa tactctgcga taccatcttt
     2941 taaatacttt tctttcagtt tcccaactgt tacaacttta attttcatga ctctattcta
     3001 acatattctc tattttttca catcttattc acaaaataaa aaatagattt caattaagaa
     3061 aatcacagtt tcaaaagagt tatccacagt ttgtgtaaaa cttttgtgtt taagttataa
     3121 ttaagctagt cagtttatac tttcagtaat tcaaacatat ggaggcaaat atgaaacatc
     3181 taaaaacatt ttacaaaaaa tggtttcaat tattagtcgt tatcgtcatt agctttttta
     3241 gtggagcctt gggtagtttt tcaataactc aactaactca aaaaagtagt gtaaacaact
     3301 ctaacaacaa tagtactatt acacaaactg cctataagaa cgaaaattca acaacacagg
     3361 ctgttaacaa agtaaaagat gctgttgttt ctgttattac ttattcggca aacagacaaa
     3421 atagcgtatt tggcaatgat gatactgaca cagattctca gcgaatctct agtgaaggat
     3481 ctggagttat ttataaaaag aatgataaag aagcttacat cgtcaccaac aatcacgtta
     3541 taaatggcgc cagcaaagta gatattcgat tgtcagatgg gactaaagta cctggagaaa
     3601 ttgtcggagc tgacactttc tctgatattg ctgtcgtcaa aatctcttca gaaaaagtga
     3661 caacagtagc tgagtttggt gattctagta agttaactgt aggagaaact gctattgcca
     3721 tcggtagccc gttaggttct gaatatgcaa atactgtcac tcaaggtatc gtatccagtc
     3781 tcaatagaaa tgtatcctta agatcggaag atggacaagc tatttctaca aaagccatcc
     3841 aaactgatac tgctattaac ccaggtaact ctggcggccc actgatcaat attcaagggc
     3901 aggttatcgg aattacctca agtaaaattg ctacaaatgg aggaacatct gtagaaggtc
     3961 ttggtttcgc aattcctgca aatgatgcta tcaatattat tgaacagtta gaaaaaaacg
     4021 gaaaagtgac gcgtccagct ttgggaatcc agatggttaa tttatctaat gtgagtacaa
     4081 gcgacatcag aagactcaat attccaagta atgttacatc tggtgtagtt gttcgttcgg
     4141 tacaaagtaa tatgcctgcc aatggtcacc ttgaaaaata cgatgtaatt acaaaagtag
     4201 atgacaaaga gattgcttca tcaacagact tacaaagtgc tctttacaac cattctatcg
     4261 gagacaccat taagataacc tactatcgta acgggaaaga agaaactacc tctatcaaac
     4321 ttaacaagag ttcaggtgat ttagaatctt aattgacatc tatgtaaaga aagctttaca
     4381 taagagaaaa gatgtgttag tgtagaatca tggaaaaatt tgaaatgatt tctatcacag
     4441 atatacaaaa aaatccctat caaccccgaa aagaatttga tagagaaaag ctagatgaac
     4501 tagcacagtc tatcaaagaa aatggggtca ttcaaccgat tattgttcgt caatctcctg
     4561 ttattggtta tgaaatcctt gcaggagaga gacgctatcg ggcttcactt ttagctggtc
     4621 tacggtctat cccagctgtt gttaaacaga tttcagacca agagatgatg gtccagtcca
     4681 ttattgaaaa tttacagaga gaaaatttaa acccaataga agaagcacgc gcctatgaat
     4741 ctctcgtaga gaaaggattc acccatgctg aaattgcaga taagatgggc aagtctcgtc
     4801 catatatcag caactccatt cgtttacttt ccttgccaga acagattctc tcagaagtag
     4861 aaaatggcaa actatcacaa gcccatgcgc gttccctagt tgggttaaat aaggaacaac
     4921 aagactattt ctttcaacgg attatagaag aagatatttc tgtaaggaag ttagaagctc
     4981 ttctgacaga gaaaaaacaa aagaaacagc aaaaaactaa ttatttcata caaaatgaag
     5041 aaaaacagtt aagaaaacta ctcggattag atgtagaaat taaactatct aaaaaagaca
     5101 gtggaaaaat cattatttat ttttcaaatc aagaagaata tagtagaatt atcaacagcc
     5161 tgaaataagg ctgttctttt atttttttat ctcacaaggt tatccactat gtttttcgat
     5221 aaaaagctta ataaatcaat aatttcttct tttatcccca acctgtggat aaagtttagt
     5281 aacattgtgg attatttttc acagcttgtg gaaaattctt gctatctatg gtaaaatatc
     5341 tctagtatta aacttttaaa tagtaaagga ggaaaaagga ttgaaagaaa aacaattttg
     5401 gaatcgtata ttagaatttg cacaagaaag actgactcga tccatgtatg atttctatgc
     5461 tattcaagct gaactcatca aggtagagga aaatgttgcc actatatttc tacctcgctc
     5521 tgaaatggaa atggtctggg aaaaacaact aaaagatatt attgtagtag ctggttttga
     5581 aatttatgac gctgaaataa ctccccacta tattttcacc aaacctcaag atacgactag
     5641 ctcacaagtt gaagaagcta caaatttaac tctttatgac tatagtccaa agttagtatc
     5701 tattccttat tcagatacgg gattaaaaga aaagtatacc tttgataact ttattcaagg
     5761 ggatggaaat gtttgggctg tgtcagccgc tttagctgtc tctgaagatt tggctctgac
     5821 ctataaccct ctttttatct atggaggacc aggccttggt aagactcact tattaaacgc
     5881 tattggaaat gaaattctaa aaaatattcc taatgcgcgt gttaaatata tccctgccga
     5941 aagctttatt aatgactttc ttgatcacct aagacttggg gaaatggaaa agtttaaaaa
     6001 gacctatcgt agtcttgatc ttttgttaat cgatgatatc cagtcactca gcggaaaaaa
     6061 agtcgcaact caggaagaat ttttcaatac ctttaacgcc cttcatgaca agcaaaaaca
     6121 gattgtccta acgagtgatc gtagtccaaa acatctagaa gggctcgagg agaggcttgt
     6181 cacgcgtttt agttggggat tgacacaaac tatcacaccc cctgactttg aaacacgtat
     6241 tgccatttta caaagtaaaa cggaacattt aggctacaat ttccaaagtg atactctaga
     6301 atacctagct gggcaatttg attcaaatgt tcgagatctt gagggagcca tcaacgacat
     6361 cactttaatt gccagagtaa aaaaaatcaa ggatatcact attgatattg ctgcagaagc
     6421 cattagagcc cgcaaacaag atgttagcca aatgctcgtc atcccaattg ataaaatcca
     6481 aactgaagtt ggtaactttt atggtgttag tatcaaagaa atgaagggaa gtagacgcct
     6541 tcaaaatatt gttttggccc gtcaagtagc catgtattta tctagagaac taacagataa
     6601 tagtcttcca aaaattggga aggaatttgg gggaaaagat cataccacag tcattcatgc
     6661 ccatgccaaa ataaaatctt tgattgatca agacgataat ttacgtttag aaattgaatc
     6721 aatcaaaaag aaaatcaaat aatttgtgga taacttttag ttttttatct tttttatcca
     6781 cattttttaa acaagctaaa aaacttgata ggacttgttt aaaggctgtt ttccacagat
     6841 ttcacagact ct
//
LOCUS       DAVLHM010000073         6847 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLHM010000073 DAVLHM010000000
VERSION     DAVLHM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.073"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(104..379)
                     /locus_tag="VXE45_001976"
     CDS             complement(104..379)
                     /locus_tag="VXE45_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0789958.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(486..1325)
                     /locus_tag="VXE45_001977"
     CDS             complement(486..1325)
                     /locus_tag="VXE45_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0789959.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1467..2315
                     /locus_tag="VXE45_001978"
     CDS             1467..2315
                     /locus_tag="VXE45_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0789960.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2408..3325)
                     /locus_tag="VXE45_001979"
     CDS             complement(2408..3325)
                     /locus_tag="VXE45_001979"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0789961.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3671..3879
                     /locus_tag="VXE45_001980"
                     /pseudo
     CDS             3671..3879
                     /locus_tag="VXE45_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4189..4482)
                     /gene="rpmA"
                     /locus_tag="VXE45_001981"
     CDS             complement(4189..4482)
                     /gene="rpmA"
                     /locus_tag="VXE45_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0789962.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4499..4843)
                     /locus_tag="VXE45_001982"
     CDS             complement(4499..4843)
                     /locus_tag="VXE45_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0789963.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4859..5173)
                     /gene="rplU"
                     /locus_tag="VXE45_001983"
     CDS             complement(4859..5173)
                     /gene="rplU"
                     /locus_tag="VXE45_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0789964.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5209..5296)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5361..6059)
                     /locus_tag="VXE45_001984"
     CDS             complement(5361..6059)
                     /locus_tag="VXE45_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0789965.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6461..6760
                     /locus_tag="VXE45_001985"
     CDS             6461..6760
                     /locus_tag="VXE45_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0789966.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2145 a         1386 c         1143 g         2173 t
ORIGIN      
        1 cggaacattc aactttttaa ctctatttat tactagattt cataattaaa aagcctactg
       61 accaagctag aaagcttgat acaataggct ttttaaagac tgattattta acagcgtctt
      121 taagagcttt accagctttg aatgctggta ctttagaagc tgcaattgtc atttctttac
      181 cagtttgtgg gttgcgacct ttacgttctg cgcgctcacg aacttcaaag ttaccaaaac
      241 cgatcaactg aactttttca ccagctgcaa gatagtcagc tactgctgca aatacagctt
      301 caactgctgc tgctgagtct ttcttagtta attctgtagc ttctgctact ttagcgatca
      361 aatcttgttt gtttgccatg ttaatgattc ctccaaataa tttctaatta acaaatataa
      421 tcatatccta aaatcccttt taggtcaagt taaaaacgct atttcttccc attttattta
      481 tttttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt gtgagtttga
      541 ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg taagctttct
      601 ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc tgctacagca
      661 cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt agttccacga
      721 cctttaacca ttggctgcaa ttcatggtct ttcatttgca tgacaacacg gatattgaga
      781 agagagctca acaagccagt tacacggcta attcgtccac ctttgacaag attttccaaa
      841 gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg agataaaatt
      901 gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg gaatttcagg
      961 gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag gctagcacct
     1021 tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc aagaatctgg
     1081 ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg tggctgactt
     1141 gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc ttctttcaaa
     1201 tccgcatcag aataaacaac attatcaatc attacagata atggaacaat tgtaatatct
     1261 aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat cttaattttt
     1321 gtcatagtat caatctttct attttaggat tcagattggt ttccttactt ctaattatat
     1381 caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa tttgatataa
     1441 tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt tttaccattt
     1501 tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc catcatctct
     1561 ttgaaggagg ggcgacaggc attaccctca tcacctttta tctttttaaa atccctgttt
     1621 ccctcatgaa cctgctgatt aatattcccc ttttcatcct agcttggaag atctttggag
     1681 ccaaatccct ctattctagt ttactaggaa ccttagcttt gtccgcctgg ttagcttttt
     1741 ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca gcccttatag
     1801 cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt acaactggcg
     1861 gaactgatat tctagctcgt attctcaaca aatacactca tatatccata ggaaaactgc
     1921 tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag gatttgagat
     1981 tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat ttgattggtg
     2041 aaggaggata tgccggcaaa ggctttatga ttatcacaaa acgtcctgac caacttgcta
     2101 aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttctggtcaa ggctactata
     2161 gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt gtgaaaacga
     2221 aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa gcccatgaaa
     2281 tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg tgacctcaaa
     2341 agttagacta aatcatctat cttttgggtt acagacaacc tcttttttgt tttatttact
     2401 caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga tccactaatt
     2461 ggtcaactga gtcaaatttg gtcatatcac gaatgcgatc aagccaataa accatgacgg
     2521 tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt gcttcttctc
     2581 catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt ctttgaatct
     2641 caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa agcactaaat
     2701 tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaactacc atacctcttg
     2761 atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct aaaatagctt
     2821 gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga acaatgataa
     2881 cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa ccaaatgtat
     2941 aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt gcaaagaatt
     3001 cttgtgcagt aagactagcg aattgactac taaaatcaag gagatataat tcttctacac
     3061 cttcgcgctt taattttctt tcacgttcag cagggttcaa aatatgcaaa aacaaatctg
     3121 gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg acgataggta
     3181 ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc cccttatgta
     3241 tgccatcaaa atagccgaga acaacgactg aatcagatgg tgtgccaata tctttttggt
     3301 tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc tatttctgga
     3361 acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca aaaagcactt
     3421 tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact tgtaggacat
     3481 cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ccataaagtg tcatactatg
     3541 ttatgtatga aaaagcaatg caactaactc ctgagaactt taaattacta attggtgccg
     3601 aaaaggtaga atttagaatc gaggtacacc tatggctgta aaatttacaa aatgagacaa
     3661 cttgggcaag atgtttgaag aatttcctaa actcccatct agtgtgcttc agactaggct
     3721 atttttctct ccatctgtta gcttggattc tcagaccgtt tcagctaaag aatatctttt
     3781 cccttatcag aaggaacggc tcaagccatt cagacaagtg aagggacgac aagccaatat
     3841 ttgaaaccag atagcagttc ttatagtcaa ttgaaataaa atctgaagaa atcgagtagg
     3901 aaactcatat caatttttaa cagtgttcta ttccagattc atactcaatg aaaattaaag
     3961 tgcaaactag gaagttagcc gcaggctgta cttgagtacg gcaaggtgaa attgacgtgg
     4021 tttgaatttg attttcgaag agtatcaatc cactatacat attaaaaagt atgggtatca
     4081 aaataaaaaa caggctctcc gaaaactcgg aaagccttat tttaagctgt ttctagcttc
     4141 ctcaccttta catttcaagg ttcgggataa aaggttcaat ggaccttttt atttagcgat
     4201 tgggtaaaca gaaacttgtt ttttatcgcg tcctttacgt tcaaagcgta ctacgccttc
     4261 aactttagcg aacaaagtat cgtctccacc acgaccaacg tttacacctg gatagatgtg
     4321 tgtaccacgt tgacggtaaa ggattgatcc acctgttaca gtttgtccgt cagctgcttt
     4381 agctccaaga cgttttgctt gtgaatcacg tccgtttgat gtagaacctc cacctttttt
     4441 gtgggcgaaa agttgcaagt tgttaagagt catttttaac ataatgtttt cctccgtgtt
     4501 agttttctgt gataactctg gtttggacga actcagaata gttctccgat aagtttgcca
     4561 tacctaagaa aaatgattca aagaataact gggtcatttc tctctggtgt gaaggaagat
     4621 cttttggtat ttcaaccatc agatagccac cttcatcttc gtttaattct aggattggtt
     4681 catagcctgc aaatttctca atagaattga taaagttaat ggcaagcgta gaaaccgatg
     4741 cacacacgac atctaagccg tattcgccac tctcggcgtg tccagtaatt tccgcactcc
     4801 tcagctcgcc atcttcggct ctctcaaaga ctgcctgtat catgtgttct ccttaaaatt
     4861 aagcgttgat tgcgttgatg acaacttttg tatatggttg acggtgacct tgtttacggt
     4921 ggctaccttt tttaggtttg tacttgtaag taaccacttt cttttgtttt ccttgttttt
     4981 caacagttcc aactacagta gctccagcaa caagtggagt tccgacaaca gtgttttcac
     5041 caccaacaag aacaacttcg ttaaaagtaa cttcttgacc agcttcaacg ttcaattttt
     5101 caacgtaaac tgcttgacca acttcaactt taacttgttt tccgccagtt ttgataattg
     5161 cgtatgtgct cattatgcac ctcctatgat ttttatgggt ttccccgatt ttttgtgaag
     5221 actcgcctag catcgtggga cgaaccactt aaacttgaat aatcaagcaa cgatgttcgt
     5281 gcggttgcac aggatcgtgc atagtcaact cttcaagtat agcatatctc ctattttctt
     5341 acaagtaata acacctaaaa tcaagctttt tcttttactt ttttctgcca agaggcaaaa
     5401 agcatgctga ggtaaaaaac gctcatcata ataggaacac caagaatggt cttttcatga
     5461 tagaaaatcg tcaaataggc tgaaaagaca acgccaagga caaaactact aagcaggcta
     5521 acaaatatga atccttcacg caaaaaagga gtgtgcttgg ttcggaaata atctccaaaa
     5581 gccagcatgg tccgtttgat attccctgtc ataaaagcgt tattataggc aatacccgac
     5641 acttctccaa aagcagttgt caccagtccc atacagaagg ccaagggcgg cactagatag
     5701 atattatcca cagtttgcgg cacaaaagca ataatgattg ataagattgc caagggaatc
     5761 aaggacagaa taggtttttt cacaattctc aatttttcct tataaatcgt taataaaaag
     5821 actcccatca taaacgctag caaggtgaga accttgtccc taacatccga aacattattt
     5881 ttaattaatt ctactgaaag aaagacaaca tttccagttt gtccagctac aagggtattc
     5941 ccgcgaacaa taaaagtgta agcatccaca tatccagcac aaaacgtcaa aaaaagtgct
     6001 aaccttttag actgacgtga tatttttctt ataggtaata acctcatttt acctcccatt
     6061 gtattttctc ttagaaatat tgtaccattt tctttctaaa aaatcgtagg ctaccattta
     6121 gattttacta ttagcataaa aataataata gacaactatt tatccaaaaa tagatagatg
     6181 taacatgttt gcaaacaaag catacgaacc tttagtaaaa tcatttccat gaaactagaa
     6241 tagagccctc ttagcaaaaa tcattatttt aatttatttc taatcactcc ttgacataaa
     6301 taactctcac caataaaaga ctatgtctta aaaaaatggt ataataaaat caatacttgg
     6361 gcttgatggc tatgctacta ataacaatta ggagagaaaa tcaggcactt gttaacaaca
     6421 aggattatcc ccttgagatg aaaggaactt tagaaatctt atgatgaaca tgcaaaacat
     6481 gatgcgtcaa gcacaaaaac ttcaaaaaca aatggaacaa agccaagctg aacttgctgc
     6541 tatgcaattt gttggcaaat ctgctcaaga tcttgtccaa gcgaccttaa ctggcgataa
     6601 gaaagttgtc agcattgatt tcaatccagc tgtcgttgac ccagaggacc ttgagactct
     6661 ttctgatatg accgttcaag ccatcaactc tgctcttgaa caaatcgatg aaactaccaa
     6721 gaaaaaactg ggtgctttcg ctgggaaatt acctttctaa aaacaaggag ctagaacaat
     6781 gcttgtcgat aacaaaggct aagaaaggtg caaaaatgac tctataatat ttgtagtggg
     6841 taaatcc
//
LOCUS       DAVLHM010000074         6700 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLHM010000074 DAVLHM010000000
VERSION     DAVLHM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.074"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(73..165)
                     /locus_tag="VXE45_001986"
                     /pseudo
     CDS             complement(73..165)
                     /locus_tag="VXE45_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(201..484)
                     /locus_tag="VXE45_001987"
                     /pseudo
     CDS             complement(201..484)
                     /locus_tag="VXE45_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(474..614)
                     /locus_tag="VXE45_001988"
     CDS             complement(474..614)
                     /locus_tag="VXE45_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0789967.1"
                     /translation="MVSCHSSLRSYIAEPILKQAGFTVQNLDGAYSLYKMVNPEGVEY
                     GN"
     gene            706..1470
                     /locus_tag="VXE45_001989"
     CDS             706..1470
                     /locus_tag="VXE45_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0789968.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2035..3414
                     /locus_tag="VXE45_001990"
     CDS             2035..3414
                     /locus_tag="VXE45_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0789969.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3428..4093
                     /locus_tag="VXE45_001991"
     CDS             3428..4093
                     /locus_tag="VXE45_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0789970.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4228..4305
                     /locus_tag="VXE45_001992"
                     /pseudo
     CDS             4228..4305
                     /locus_tag="VXE45_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4493..5032
                     /locus_tag="VXE45_001993"
     CDS             4493..5032
                     /locus_tag="VXE45_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0789971.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            5099..5509
                     /locus_tag="VXE45_001994"
     CDS             5099..5509
                     /locus_tag="VXE45_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0789972.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5625..>6700
                     /gene="pavB"
                     /locus_tag="VXE45_001995"
     CDS             5625..>6700
                     /gene="pavB"
                     /locus_tag="VXE45_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0789973.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKA"
BASE COUNT         1828 a         1291 c         1536 g         2045 t
ORIGIN      
        1 aaaacagtgt tttgagctga cttcgtcagt tccatccaca accttaaaac agtgttttga
       61 gctgacttcg tcagttccat ccacaacctt aaaacagtgt tttgagcagc ctgcggctaa
      121 cttcctagtt tgcactttaa ttttcattga gtattacttc atcttctcat gaaattgagt
      181 ttttgcccag ctcctcttga ttattctact tgaccgggcc aagcattcat accaccttct
      241 acgttggtaa cggtgaggcc ttgggagctg agaaattggc aggtagatgc agagcggact
      301 cctccgtgac aaatgacata gtattcatgg tcaggtttga gttctttgta gccttgctct
      361 aaggtattta tggaagattt ttgggtcctg cttggaattc atgtgcttca cggacatcga
      421 taagttccag attttcattt tgatattttc tataaaagtc agccatgctg atactagttt
      481 ccatattcta ctccttctgg gttaaccatt ttgtatagtg aataagcgcc gtcaaggttt
      541 tggacggtaa atcctgcttg cttgaggata ggctctgcga tatagctgcg caaactactg
      601 tggcaactga cgatgtaggc ttgtttttct cctcagttca tcagcttcct ccttgacact
      661 cggtcagatt ttgatacaat agtacaaaat tagaggaggt gggctatgat tcagaaacat
      721 gcgattccca ttttagagtt tgatgataat cctcaggcgg ttatcatgcc caatcacgag
      781 gggttggatt tgcagttgcc aaagaagtgt gtctatgctt ttttaggtga ggagattgac
      841 cgctatgcga gggaagtagg ggcgaactgt gttggcgaat tcgtttctgc taccaagacc
      901 tatccagtct atgtcatcaa ctacaagggt gaggaggtct gtctggctca ggctcctgtt
      961 ggctccgctc cagcagccca gtttatggat tggttgattg gctatggtgt ggagcagatt
     1021 atctctactg ggacctgtgg tgtcctagct gatatagagg aaaatgcctt tctagtccct
     1081 gttcgcgctc tgcgagatga aggagccagt taccactatg tggcaccttc tcgttatatg
     1141 gaaatgcagc cagaggctat tgctgccatt gagcgagttt tggatgatag agggattcct
     1201 tatgaagaag tcatgacctg gtccacagat ggtttttacc gagaaacggc tgaaaaggtg
     1261 gcttatcgta aggaagaagg ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca
     1321 gtagctcaat tgcgtggagt tctctggggt gaattgttgt tcacagcaga ttctctagcg
     1381 gacttggacc agtacgacag tcgtgactgg ggctcggaag cttttaataa ggcactagaa
     1441 ctgagtttag caagtgttca ccacctttag ttgtactggc aaaggatttg ttttatcata
     1501 aaatgtctag ctcatacttt tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct
     1561 aggcatgttg aggttgggaa aaatctttaa aatcagaaaa acgtatcata tcaggtgatg
     1621 aaaattttga tactatgcgt tttatgttgg taagatttag agtgagatga aatgatactc
     1681 ttcgaaaatc tcttcaaacc aggtcagctt caccttgccg tatagatgtt actgacttcg
     1741 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgtgactag ctttctaagc
     1801 gatgccttgg ttctcattgc ctataatcaa aaagagaaat tttctcctga aaagcatata
     1861 gagtagctgg cgttaaaagc tcctgtcttg cttttttgac ctatagtcac atctatcaag
     1921 tattgttctt gcctaagcta tcaataaaaa ggtggcattt tttaggcttg gtgttagtag
     1981 attttgcctt atcctatcta agtcatttcg aactttttat ggtacaatgg aaacatgtta
     2041 ttcaaattat ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc agcccgtcgt
     2101 atttttttga gttttgcctt ggtcatttta ctaggctctc ttcttttgag cttgcccttt
     2161 gtccaagttg aaagctcacg agcgacttat tttgatcatc ttttcactgc tgtctctgca
     2221 gtctgtgtga caggtctctc aacccttcca gtagctcaca cctataatat ctggggccaa
     2281 ataatctgtt tgctcttgat tcagatcggt ggtctagggc tcatgacctt tattggggtt
     2341 ttctatatcc agagcaagca aaagcttagt cttcgtagcc gtgcaactat tcaggatagt
     2401 tttagttatg gagaaactcg atctttgaga aagtttgtct attctatttt tctcacgacc
     2461 tttttggttg agagcttggg agctattttg cttagttttc gccttattcc tcaacttggc
     2521 tggggacgtg gtctttttag ttccattttt ctagcgatct cagccttctg taatgccggt
     2581 tttgataatt tagggagcac cagtttattt gcttttcaga ccgatttact ggtcaatctg
     2641 gtgattgcag gcttgattat tacaggcggc cttggtttta tggtctggtt tgatttggct
     2701 ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc atacgaagct tgtactatta
     2761 ttgactatag gtttgttgtt atttggaaca gcaactactc tctttcttga gtggaacaat
     2821 gctggaacga ttggcaatct ccctgttgcc gataaggttt tagttagctt ttttcaaaca
     2881 gtgacgatgc gaacagctgg cttttctacg atagattata ctcaggctca tcctgtgact
     2941 cttttgattt atatcttaca gatgtttcta ggtggggcac ctggaggaac agctggggga
     3001 ctcaagatta cgacattttt tgtcctcttg gtctttgcac gaagtgagct tctaggcttg
     3061 cctcatgcca atgttgcgag acgaacgatc gcgccgcgaa cggttcaaaa atcctttagt
     3121 gtctttatta tctttttgat gagcttcttg ataggattga ttctgctagg gataacagcc
     3181 aaaggcaatc ctccctttat ccacctcgta tttgaaacca tttcagctct tagtacagtt
     3241 ggtgtaacgg caaatctgac tcctgacctt gggaaattgg ctctcagtgt tatcatgcca
     3301 cttatgttta tgggacgaat tggtcccttg accttgtttg ttagcttggc agattaccat
     3361 ccagaaaaga aagatatgat tcactatatg aaagcagata ttagtattgg ttaagaaagg
     3421 aaagagcatg tcagatcgta cgattggaat tttgggcttg ggaatttttg ggagcagtgt
     3481 cctagctgcc ctagccaagc aggatatgaa tattatcgct attgatgacc acgcagagcg
     3541 catcaatcag tttgagccag ttttggcgcg tggagtgatt ggtgacatca cagatgaaga
     3601 attattgaga tcagcaggga ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa
     3661 tctggagtcg agtgtgcttg cggttatgca ctgtaagagt ttgggggtac cgactgttat
     3721 tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa aagattggag ctgactcggt
     3781 tatctcgcca gagtatgaaa tggggcagtc tctagcacag accattcttt tccataatag
     3841 tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc
     3901 ttgggcaggt caaagtctga gtaaattaga cctccgtggc aaatacaatc tgaatatttt
     3961 gggtttccga gagcaggaaa attccccatt ggatgttgaa tttggaccag atgacctctt
     4021 gaaagcagat acctatattt tggcagtcat caacaaccag tatttggata ccctagtagc
     4081 attgaattcg taaagaggga tgacccctct tttttgatgc ctaagatggc aaatagagac
     4141 agaagcccct tgtcttctag taaaagttct tcaaaggctg gactttatgg taaaatagaa
     4201 agaagtgaca agagagagta atactcaatg aaaatcaaag atcaaactag gaaactagct
     4261 acgggctgct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa
     4321 cactgttttg aggttgcaga tagaactgac gaagtcagct caaaacactg ttttgaggtt
     4381 gcagatagaa ctgacgaagt cagtaacatc tatacggcaa ggcgacgttg acgcggtttg
     4441 aagagatttt cgaagagtat aagaaaaaat cagtccccta aaggagtaga ttatgaagtt
     4501 attgtctatc gcaatttcta gctataatgc agcagcctat cttcattact gtgtggagtc
     4561 gctagtgatt ggtggtgagc aagttgggat tttgattatc aatgacgggt ctcaggatca
     4621 gactcaggaa atcgctgagt gtttagctag caagtatcct aatatcgtta gagccatcta
     4681 tcaggaaaat aaatgccatg gcggtgcggt caatcgtggc ttggcagagg cttctgggcg
     4741 ctattttaaa gtagttgaca gtgatgactg ggtggatcct cgtgcctact tgaaaattct
     4801 tgaaaccttg caggaacttg agagcaaagg tcaagaggtg gatgtctttg tgaccaattt
     4861 tgtctatgaa aaggaagggc agtctcgtaa gaagagtatg agttacgatt cagtcttgcc
     4921 tgttcggcag atttttggct gggaccaggt cggaaatttc tccaaaggcc agtataccat
     4981 gatgcactcg ctgatttatc ggacagattt gttgcgtgct agccagttct aactgcctga
     5041 acatactttt tatgtcgata atctctttgt ctttacgccc cttcagcagg tcaagaccat
     5101 gtactatctg cctgtcgatt tctatcgtta tttgattggg cgtgaggacc agtctgtcaa
     5161 tgagcaagtg atgattaagt gcattgacca gcaactcaag gtcaatcgac tcttgataga
     5221 ccaacttgat ttgtcccaag tgagtcatcc caaaatgcga gaatatctgc tgaatcatat
     5281 tgaactcacg acggtgattt ccagtaccct gctcaaccga tctggaacag cggagcatct
     5341 ggcaaaaaaa cgccaattgt ggacctatat tcagcagaaa aatccagaag tctttcaggc
     5401 tattcgtaag accatgttga gccgtttgac caaacattct gtcttgccag atcgcaaact
     5461 gtccaatgtc gtctatcaaa tcaccaaatc tgtttatgga tttaattaat ataagtgttt
     5521 tataagaggg atttaagaaa aattttaact ttttcttagt cctttttaat ttcaggagat
     5581 tatactagag tcatcaaata aagaaagact ctaaggagaa tcctatgaaa ttcaatccaa
     5641 atcaaagata tactcgttgg tctattcgcc gtctcagtgt cggtgttgcc tcagttgttg
     5701 tggctagtgg cttctttgtc ctagttggtc agccaagttc tgtacgtgcc gatgtggtca
     5761 atccgacccc aggtcaagtc ttacctgaag agacatcggg aacgaaagag ggtgacttat
     5821 cagaaaaacc aggagacacc gttctcactc aagcgaaacc tgagggcgtt actggaaata
     5881 cgaattcact tccgacacct acagaaagaa ctgaagtgag cgaggaaaca aactcttcta
     5941 gtctggatac actttttgaa aaagatgaag aagctcaaaa aaatccagag ctaacagatg
     6001 tcttaaaaga aactgtagat acagctgatg tggatgggac acaagcaagt ccagcagaaa
     6061 ctactcctga acaagtaaaa ggtggagtga aagaaaatac aaaagacagc atcgatgttc
     6121 ctgctgctta tcttgaaaaa gctgaaggga aaggtccttt cactgccggt gtaaaccaag
     6181 taattcctta tgaactattc gctggtgatg gtatgttaac tcgtctatta ctaaaagctt
     6241 cggataatgc tccttggtct gacaatggta ctgctaaaaa tcctgcttta cctcctcttg
     6301 aaggattaac aaaagggaaa tacttctatg aagtagactt aaatggcaat actgttggta
     6361 aacaaggtca agctttaatt gatcaacttc gcgctaatgg tactcaaact tataaagcta
     6421 ctgttaaagt ttacggaaat aaagacggta aagctgactt gactaatcta gttgctacta
     6481 aaaatgtaga catcaacatc aatggattag ttgctaaaga aacagttcaa aaagccgttg
     6541 cagacaacgt taaagacagt atcgatgttc cagcagccta cctagaaaaa gccaagggtg
     6601 aaggtccatt cacagcaggt gtcaaccatg tgattccata cgaactcttc gcaggtgatg
     6661 gtatgttgac tcgtctcttg ctcaaggcat ctgacaaggc
//
LOCUS       DAVLHM010000075         6657 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLHM010000075 DAVLHM010000000
VERSION     DAVLHM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.075"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            60..923
                     /locus_tag="VXE45_001996"
     CDS             60..923
                     /locus_tag="VXE45_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0789974.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1306..1926
                     /locus_tag="VXE45_001997"
     CDS             1306..1926
                     /locus_tag="VXE45_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789975.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2012..2455
                     /gene="tsaE"
                     /locus_tag="VXE45_001998"
     CDS             2012..2455
                     /gene="tsaE"
                     /locus_tag="VXE45_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0789976.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2445..2963
                     /locus_tag="VXE45_001999"
     CDS             2445..2963
                     /locus_tag="VXE45_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0789977.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2971..3987
                     /locus_tag="VXE45_002000"
     CDS             2971..3987
                     /locus_tag="VXE45_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0789978.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4072..5328
                     /locus_tag="VXE45_002001"
     CDS             4072..5328
                     /locus_tag="VXE45_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0789979.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5383..6549
                     /gene="recA"
                     /locus_tag="VXE45_002002"
     CDS             5383..6549
                     /gene="recA"
                     /locus_tag="VXE45_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0789980.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
BASE COUNT         2118 a         1084 c         1497 g         1958 t
ORIGIN      
        1 tattttgaac taaaaacttt ataatgaaat taagcaaata ggaaggttta ttatctttaa
       61 tgaatacact cgcagagaaa ttcagattga aaagaaaaga gttgagactc tcccaacaaa
      121 ctcttgcaga aggaatttgt gaacaaagcc agattagtaa aattgaaaga ggtcatttta
      181 ttccctccgc agacttgtta ttcaaactct ctcaacgact tgaagtccct ttggattact
      241 ttttcaatga acaaatcgaa gttaagtcta acctctctaa tttcaaacat ctatctgctc
      301 gcctattaga tgacagaaat tatgacgatt tagaatatct ttataaaata gaggtagaac
      361 gaagcacttt tctaacatta gaagaccgaa cttaccttga atggattaaa tctataattg
      421 acttctatca atatgacagt aagtgtgagg caatttcgtc attggaaaat atattattaa
      481 aagtctcttc aaatactctg atttatttaa aggcgttgaa tactctatct aatttctatt
      541 ccttagtggg tcgtgaacaa gaatatgagg caaactactc tcatttaata gagttgtatc
      601 agacaaaaaa tttggaccat caagagtttt tatttggcta catcagagtt cgttacaact
      661 acgctcacta cctagtatca aaggaaaaat ataatgaagc catccaagaa gctcttgaaa
      721 cgattgaact ctgtaaacaa agacagacaa gctaccaatt ggctcctcta cttattcttg
      781 taggaaatgc tggagccaaa tttctagaca gagaacaagt caaaaattat tatatagaag
      841 caagagagtt atgtaagatt tataacaatc ctttaatgtt gatgaagata gaaaattatt
      901 tgaaggaact agatactgtt tagttaatct tgacattata gtttttctga aacgttaaat
      961 aacctgtaag gctgatagtt agattaatac tatcagcctt ataattatgt gactctgagt
     1021 ccgtctcgct ccgtgaggtg cgagacaaaa caatcacccg tttgacggat tttcatgatt
     1081 tcaaatttat attcttcgaa aatctcttca aatcacgtca gctctatctg caatctcaaa
     1141 acactgtttt gagcaacctg tggctagcta cctagtttga tctttgattt tcattgagta
     1201 ttagtctcta gtgtttgttt agcgtcttaa agagacattt gagaagatta gaaacagttc
     1261 tctcttttct cctagtataa tgattggtag gaagggagag agaagatgaa atcaatgaga
     1321 atcttatttt tgttagcttt aattcaaatc agtttgagta gctgtttcct atggaaggaa
     1381 tgcatcttgt cctttaaaca aagtacagct tttttcatcg gaagcatggt tttcgtttca
     1441 ggaatctgtg ctggagtaaa ttatctttat acccgtaagc aagaagtcca tagtgtccta
     1501 gccagtaaga agtcggtgaa gcttttttac agtatgttac tcttaattaa tttgttagga
     1561 gctgttcttg ttttgtcaga taacttgttc atcaaaaata cgctgcagca agaattagtt
     1621 gactttttat tgccatcctt ctttttccta tttgggctag atttgctgat ttttttaccc
     1681 ttgaaaaaat acgtgcgcga ttttcttgct atgctggaca gaaaaaagac agtgttggtg
     1741 actattttag caacacttct tttcttaaga aatccaatga ccattgtctc acttctgatt
     1801 tatattggac tgggcttgtt ttttgcagcc tatcttgtcc caaattcggt taagaaggaa
     1861 gtttcctttt atggtcatat tttccgagat cttgtattgg tcattgttac gctcattttc
     1921 ttttagagaa agcctgtttt ttatggatgt tatgatgata agtttagtag gaaaatagac
     1981 acaaaagaaa agtttttggt ataataagag tatgtacaca aaaaatgaag aagagttgca
     2041 agccttaggg gagcgtttgg gccatctatt agcaaagaat gatgttttaa tcttaactgg
     2101 agaactgggt gcaggtaaaa cgacctttac taaaggactt gcaaaaggat tacagatttc
     2161 tcaaatgatt aaaagtccca cctatactat cgtgagagag tatgaaggtc gacttccact
     2221 ttatcaccta gatgtttatc gtattgaagg agatgctgat tctatcgact tggatgagtt
     2281 tatctttggt ggcggcgtga ctgttattga gtggggaaat ctcttaggag atgccttgcc
     2341 agatgcttat ttagaattgg aaattctaaa agaagcagat ggacgccgtt taaattttca
     2401 ggcaaagggt ttgcgtgctg agaaattgtt agaggagctt caatatggag tatgaattgc
     2461 tcattaggga agcagagccc aaagatgcag ctgaattagt ggccttttta aatcgtgtga
     2521 gtttggagac agactttacc agcctagacg gagatggtat tctcttgact agtgaggaga
     2581 tggaaatatt cctcaacaag caagctagtt cggacaatca gataacctta cttgcattct
     2641 taaatggcaa aattgctggt attgtaaata ttacagctga tcagcgtaag agagtccgtc
     2701 atattggaga tctcttcatt gtgattggaa aaagatattg gaataatggc ttgggaagtt
     2761 tgttgctaga agaagcgata gagtgggcac aagcaagtgg cattctgcgt cgtctccaac
     2821 tgactgtcca aactcgtaat caagcagcag tccatcttta tcaaaagcat ggctttgtca
     2881 ttgaaggtag ccaagagcgt ggggcatata tagaagaagg gaaatttatc gatgtttact
     2941 tgatgggtaa actgataggt tagtagaaat atggttaaaa aaattattgg aatggtgcta
     3001 gctttacttt ctgtaactgt agtaggagta ggtgtttttg cttatactat ttatcaacaa
     3061 gggacagaaa ccttagctaa aacctataaa aaaatcggtg aagaaaccaa ggttattgaa
     3121 gcgactgaac ctctaaccat tctgttaatg ggagtggaca ccggaaatgt tgaacgaact
     3181 gaaacttggg tcggtagaag tgatagcatg atcttgatga cagtgaatcc taaaacgaaa
     3241 aaaacaacaa tgatgagttt agagcgggat attctgacgc gcattgaatc agggaatggt
     3301 caggctcatg aagcgaaact gaactcagca tatgcagatg gtggagcaga gcttgctata
     3361 gaaaccattc aaaaaatgat gaatatccat attgatcgct atgtgatggt caatatgaga
     3421 gggttgcaaa aattagtgga tgcagtagga ggtattacag tcaataatat cctaggtttc
     3481 ccaatttcta tcagtgacca agaagaattt aataccattt ctatcggtgt tggggagcaa
     3541 catattgggg gagaagaagc cctagtctat gcacgaatgc gttaccaaga tcctgagggg
     3601 gattatggtc gtcaaaaacg tcaacgtgaa gttattcaaa aagtcatgga aaaagctctc
     3661 agtttaaata gcattggtca ttatcaagag attctaaaag ctttgagtga caatatgcag
     3721 accaatattg atttgtctgc aaaaagtatc cctaacttgc taggctataa agattcattt
     3781 aaaaccattg aaactcagca gttgcagggt gaaggagaga tacttcaagg tgtttcttac
     3841 cagattgttt cgagagcaca tatgttggaa atgcaaaata tactccgacg ttctttggga
     3901 caagaagaag ttactcagct tgaaaccaat gcggttttat ttgaagattt atttggcaga
     3961 gcacctgttg gtgatgaaga taattaactt ttgatacaaa taaaaaaatc aatcgtagga
     4021 aaattcctgc gattttttca aaaaaatacg aatagatagg taggaggaaa catgaaagca
     4081 gaaatcattg ctgttggaac agagattttg acaggacaga ttgtcaacac caatgcccag
     4141 tttttgtcgg aaaaactagc tgagattggg gtagatgtat attttcagac ggctgtagga
     4201 gacaatgaag ttcgtctctt gtctttgctt gagattgcca gtcaacgtag cagtctggtg
     4261 attttgacag gcggtttggg gccaactgag gacgacctaa ccaaacaaac cctagctaaa
     4321 tttttaggga aagcattagt ctttgatcct caggctcagg agaagttgga tatctttttt
     4381 gccctgcgac cagactatgc ccgaacaccg aataacgaaa gacaagctca aattgtagaa
     4441 ggagcgattc cactgccaaa cgaaacagga ctggctgttg gaggaaaatt agaagtagac
     4501 ggagtgacct atgtcgtcct tccaggtccg ccaagtgaat tgaaacccat ggtcttaaac
     4561 caacttctac ccaagttgat gacagggagc aagctgtatt cccgagttct tcgtttcttt
     4621 gggattggcg agagccagtt ggttacgatt ttggctgatt taattgataa tcagatcgat
     4681 cctaccttgg ccccttatgc caagacagga gaagtcactc tacgtctgtc aacaaaggct
     4741 agcagtcaag aagaggcgaa tcaagcgctg gatatcttgg aaaatcaaat cttggactgc
     4801 cagactttcg aaggaatttc tttacgagac ttttgctatg gttatgggga agaaactagt
     4861 ttagccagca ttgtggtaga agaactgaaa aggcaaggga aaaccatcgc ggctgcagag
     4921 agtttgacgg caggtctttt ccaagctacc gtggcgaatt tttctggagt ttcaagtata
     4981 tttgagggtg gttttgtgac ctatagcttg gaggaaaaat caaggatgtt ggatattcct
     5041 gccaagaatt tggaagaaca tggtgtggtg tctgaattta cagctcagaa gatggctgag
     5101 caggcacgaa gcaagaccca gtctgatttt ggaattagtt tgactggagt ggcaggacca
     5161 gatagcctag aaggacaccc agttgggaca gtcttcatag gcttggcgca agatcaagga
     5221 actgaggtta tcaaggttaa tattggaggc agaagccgag cagatgtacg tcacattgcg
     5281 gttatgcatg cctttaacct agttcgcaag gctttattaa gtgactaact tttgatataa
     5341 tagtagatag gtctgaggat cattagaatg taggagaata gaatggcgaa aaaaccaaaa
     5401 aaattagaag aaatttcaaa aaaatttggg gcagaacgtg aaaaggcctt gaatgacgct
     5461 cttaaattga ttgagaaaga ctttggtaaa ggatcaatca tgcgtttggg tgaacgtgcg
     5521 gagcaaaagg tgcaagtgat gagctcaggt tctttagctc ttgacattgc ccttggctca
     5581 ggtggttatc ctaagggacg tatcatcgaa atctatggcc cagagtcatc tggtaagaca
     5641 acggttgccc ttcatgcagt tgcacaagcg caaaaagaag gtgggattgc tgcctttatc
     5701 gatgcggaac atgcccttga tccagcttat gctgcggccc ttggtgtcaa tattgacgaa
     5761 ttgctcttgt ctcaaccaga ctcaggagag caaggtcttg agattgcggg aaaattgatt
     5821 gactcaggtg cagttgatct tgtcgtagtc gactcagttg ctgcccttgt tcctcgtgcg
     5881 gaaattgatg gagatatcgg agatagccat gttggtttgc aggctcgtat gatgagccag
     5941 gccatgcgta aacttggcgc ctctatcaat aaaaccaaaa caattgccat ttttatcaac
     6001 caattgcgtg aaaaagttgg agtgatgttt ggaaatccag aaacaacacc gggcggacgt
     6061 gctttgaaat tctatgcttc agtccgcttg gatgttcgtg gtaatacaca aattaaggga
     6121 actggtgatc aaaaagaaac caatgtcggt aaagaaacta agattaaggt tgtaaaaaat
     6181 aaggtagctc caccgtttaa ggaagccgta gttgaaatta tgtacggaga aggaatttct
     6241 aagactggtg agcttttgaa gattgcaagc gatttggata ttatcaaaaa agcaggggct
     6301 tggtattctt acaaagatga aaaaattggg caaggttctg agaatgctaa gaaatacttg
     6361 gcagagcacc cagaaatctt tgatgaaatt gataagcaag tccgttctaa atttggcttg
     6421 attgatggag aagaagtttc agaacaagat actgaaaaca aaaaagatga gccaaagaaa
     6481 gaagaagcag tgaatgaaga agttccgctt gacttaggcg atgaacttga aatcgaaatt
     6541 gaagaataag ctgttaaagc agtggagaaa tccgctactt tttcgatttt tgattcaagt
     6601 ttttagatta tatattatat atagtagctt gaaataagat atgaacaact ttattag
//
LOCUS       DAVLHM010000076         6025 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLHM010000076 DAVLHM010000000
VERSION     DAVLHM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.076"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1420
                     /locus_tag="VXE45_002003"
     CDS             <1..1420
                     /locus_tag="VXE45_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0789981.1"
                     /translation="FMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAIL
                     DLLMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNI
                     TSEVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPV
                     LTLIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVF
                     NTKSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESG
                     SGKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENL
                     TFGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLS
                     KPSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIV
                     EIGTHRELLELGGIYKQLYSNN"
     gene            1444..3182
                     /locus_tag="VXE45_002004"
                     /pseudo
     CDS             1444..3182
                     /locus_tag="VXE45_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            3233..4000
                     /locus_tag="VXE45_002005"
     CDS             3233..4000
                     /locus_tag="VXE45_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0789982.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            4002..4634
                     /locus_tag="VXE45_002006"
     CDS             4002..4634
                     /locus_tag="VXE45_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0789983.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(5580..5993)
                     /gene="ndk"
                     /locus_tag="VXE45_002007"
     CDS             complement(5580..5993)
                     /gene="ndk"
                     /locus_tag="VXE45_002007"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0789984.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
BASE COUNT         2107 a          873 c         1101 g         1944 t
ORIGIN      
        1 ttttatgaaa catttgatat atttacctta cagtttttat gaaaaacgta ctttagggga
       61 tatacttttt agagctaact ctattgttta tataagagaa atactatcaa ataattttat
      121 agcagctata cttgatttgt taatgattgt ggtttatgct gtggttttat ttagcttttc
      181 taagtacatg gtaatctttt taatatcact aagtctagct ctatctattg taatgtatcc
      241 aatcataaaa atctcaaaaa atttaattga taaaaatata aaagaaaagg ttaatgttca
      301 aaatattact tccgaagtaa tttctaaaaa tagtgatatt aagctaactg gagaagagga
      361 attttggatt aacaaatggg ataattttaa tacaaaacag ctcatcatag gtcgaaaact
      421 tgatatacat ttatcaattg ttagtagtat aacgaatgtt ttacaaatta ttctccctgt
      481 tttgaccctt attgtaggtg taaatataaa aacattcgaa caattgacgt taggacaaat
      541 tgtagcaata agtacagtct caccatactt tatttctcct ataatttctt taagtgataa
      601 ctatatacaa ttaatgttat taaagggata ttttttaaga atagaggatg tgtttaatac
      661 taaatccgaa ttaattccag aaagagtcag tcaagatata aaatttgata aaaaaataga
      721 attaaaagat atttggtata aatatggatt atttgatgat tatgttttga aaggaataaa
      781 tgttactatt aaaaaaggag aaactgttgc tattgttgga gaatcaggtt caggtaagag
      841 tacattagct aaaattttat taggtttatt agaacctaat attggttcaa tagaagttga
      901 tggagtagaa aaagaagaaa ttggtcaaac attgtataga aagatttttg gagcagtgtt
      961 acaaaattca accctaagtt atggtacctt aagagagaat ttgacatttg gacactttgt
     1021 ttcagatgaa gaattaatga caaatctaaa ttcaattggt cttagcaatg tagttaaatc
     1081 tttacctctt ggattagaga caatcatcgc tgaagaaggt aataactttt ctggagggca
     1141 gcagcaaatg atacttttag ctcgttgtct tttgtcgaaa ccttcggtag ttgttttgga
     1201 cgaagcaaca agtagtttag ataatttatc tcaacaaatt acaacttctt acttaagtga
     1261 aatcggtacc actaagattt taattgccca tcgactagat actatcaagt ctgcagataa
     1321 gatcttagta atgcataatg gtgaaattgt agagattggg acccatagag aacttcttga
     1381 actaggaggc atttataagc aattgtattc aaataattag tttttgatta aaagggtaaa
     1441 tttatgaaga ttatgaaaaa aaaatattgg actttagcga tattattctt ttgtttgttc
     1501 aataattctg ttactgctca agaaatacct aaaaatcttg atggcaatat aactcacact
     1561 cagactagcg aaagtttttc tgaatctgat gaaaaacagg ttgactattc taataaaaat
     1621 caagaagaag tagaccaaaa taaatttcgt attcaaatcg ataagacaga attatttgta
     1681 acaacagata aacatttaga aaaaaactgt tgtaaattgg aacttgaacc acaaataaat
     1741 aacgatattg ttaactctga aagtaataat ttactaggcg aagataattt agataataaa
     1801 attaaggaaa atgtttctca tctagataat agaggaggaa atatagagca tgacaaagat
     1861 aacttagaat cgtcgattgt aagaaaatat gaatgggata tagataaagt tactggtgga
     1921 ggcgaaagtt ataaattata ttctaaaagt aattctaaag tttcaattgc tattttagat
     1981 tcaggagtcg atttacaaaa tactggatta ctgaaaaatc tttcaaatca ctcaaaaaac
     2041 tatgtcccca ataaaggata tttaggaaaa gaggagggag aggaaggaat aatatcagat
     2101 attcaagata gattaggtca tggtacggct gttgtagctc aaattgtagg ggatgacaat
     2161 attaatggag taaatcctca cgttaatatt aacgtctata gaatatttgg taagtcgtca
     2221 gctagtccag attggattgt aaaagcaatt tttgatgctg tagatgatgg caatgatatt
     2281 atcaatctta gtactggaca atatttaatg attgatggag aatatgagga cggaacaaat
     2341 gattttgaaa catttttgaa gtataaaaag gctattgatt acgcgaatca aaaaggagta
     2401 attatagtag ctgcattagg gaatgactcc ctaaatgtat caaatcagtc agatttattg
     2461 aaacttatta gttcacgcaa aaaagtaaga aaaccaggat tagtagttga tgttccaagt
     2521 tatttctcat ctacaatttc ggtcggaggc atagatcgct taggtaattt atcagatttt
     2581 agcaataaag gggattctga tgcaatatat gcgcctgcag gctcaacatt atctctttca
     2641 gaattaggac ttaataactt tattaatgca gaaaaatata aagaagattg gattttttcg
     2701 gcaacactag gaggatatac gtatctttat ggaaactcat ttgctgctcc taaagtttct
     2761 ggtgcgattg caatgattat tgataaatac aaattaaaag atcagcccta taattatatg
     2821 tttgtaaaaa aattctggaa gaaacattac cagtaaaaaa tggtataaaa gtgttaaata
     2881 taccaaacgt attgagatat gatttgaata tgttacaatt agaatataaa aatgaacaaa
     2941 gttgggatag tttcatagat aatgttaatt taattgagtt ggaagagaga attcaaacta
     3001 ctattggaat taaacaaata aacacacaca atattattac tattgcccga gaagggtact
     3061 ctcaaaatta tttacctaac acttcagaaa atacatataa ttcattacaa gtcagtttag
     3121 ttggagtatt actacttttt ataagtatgg taaatatttt atgggctaaa aaaagtaaat
     3181 gaaaataaaa tttggagccc tctgaaaaag taagtcctac agttcaacta aaatgagtca
     3241 aaagatgaat caccttgatg taggggagtt tgtcttattg ctgcctgaac acctccgttc
     3301 agaggaagaa cattataaat ctgtttttga agacgactta accagtcgca tatctagtca
     3361 agatgaacga cagcaaatga ctgctacggt aggttattta gaatcaggtc aggatcgttt
     3421 tgtgtataat acgaccccta tttcttacca gcagtttttg aaagatccaa tcatcattgt
     3481 tataacaccc caatcaactg gtccacagtc cattttgttt tggatagacg cagtacagaa
     3541 ctacgttctc tttaatcaat tgtctgatgc ccaggagctt atccagagac aaggcattga
     3601 aaattgggtc tcagaaatgc aaacaggtta ccacaactac atcacattat tggataatat
     3661 ccagagggaa cgttgggtaa tgctagcagg agctgtgctt gggattgcaa cttcaatctt
     3721 gttgtttaac actatgaata ggctctactt tgaagaattt agacgtgcca tttttatcaa
     3781 acgcattgca ggtctcaggt tcttagaaat ccatcgcact tatctctttg ctcaactggg
     3841 tgtgttttta ctgggatttg ttgcgagtgt atttcttcag gtagagatag gagttgcttt
     3901 cttagtcttg ttactcttta ctggtctatc tcttttacag ttacatgtcc aaatgcagaa
     3961 agaaaacaag atgtccatgc ttgttttgaa gggaggttaa tatgattgaa cttaaacagg
     4021 tgagtaaatc ttttggagaa cgagagttat tttcgaatct ttcaatgaca tttgaggctg
     4081 gaaaagtcta tgccttaatt ggttcaagtg gtagcggaaa aacaaccttg atgaacatga
     4141 ttgggaaatt agaaccttat gatgggacga ttttttaccg aggtaaagac ttggccaatt
     4201 ataaatcaag tgattttttc cgtcacgaat tgggctacct cttccagaac tttggcttaa
     4261 ttgaaaacca aagtattgaa gaaaacctta agctaggtct cattggtcaa aagttgagtc
     4321 ggtcggaaca gcggttgagg cagaagcagg ctttagaaca ggtcggcctg gtttatcttg
     4381 acctagataa gcgcatcttt gagttatcgg gcggagaatc gcaacgggtt gccttggcaa
     4441 aaattatctt aaagaatcca ccctttattc tggcagatga gccaacagct tcaatagacc
     4501 cagcaacctc tcagttgatt atggagattt tgctatctct tcgagatgat aataggctaa
     4561 tcattatcgc aacacataat ccggcaattt gggagatggc tgatgaagtg ttcacgatgg
     4621 atcatctgaa ataaaaatcc ttgtttttaa ttgcacgatg agttactgaa atattatcat
     4681 gaatcaagaa ttggagttaa tttagaattg tacttaattt agaattgtac tttattaata
     4741 ttgaggtaac tttttcttga taaaggaaga aataatggag aggaagttag aatgaaaaaa
     4801 ttcgacaatt atattattga gaagccttgc gattctaatt cagataaact gcaaaaaatc
     4861 ttaataattg aaagtttggt agatgatatt ttgcaatttt ctctcagaat caataatagt
     4921 gtaggagaga ttttcctcct acaaccgttt taaaagaaaa ctatctttat tccatgttat
     4981 tttgaggaag atattgtgaa agtcaaagat gatgataaag ttgagtggaa tttgttagaa
     5041 tttcaaaaat ttagagcatt tttggcttag taatctgtgt tgaaggctca aaacctatgg
     5101 taaaaaagta gctttgaaaa cgtattgcct ccaaagattt agttaaataa tgatttaaca
     5161 caaaaagaaa ttattgaagt tctggaaaga tgttgtttca gtattgagaa aaggtgggaa
     5221 aaacttgcga ttttcacaga gaaaggaaga aaaagtatag aaatatagtc aattgaaaca
     5281 agaacaggat aaaagaacct tttgtgccat atttttctcc tttcgcttta caattggatt
     5341 gaacaccttt attgtatcgc gtatggagtt tttttggtat aaccttcgac gcacacccgc
     5401 atagcgggtg ttttttttgt ctcgcaccta acggagcgag acaaactaat agtcacttaa
     5461 tcaaaaaacg caccatatca aaaactaaaa agtttgatat catgcgtcat gtcttaaact
     5521 aattgactat actttctatt caaatgagct tttaaccaat tgattgagcc aatccactct
     5581 taaaaccaaa gagcaatttc tcgcttagct gactcttctg aatctgaacc atgtacaaca
     5641 ttttggataa tctcattttc tccagcagct tttgcaaaat cacctcgaat agtgcctggt
     5701 aaagcttctt ctggacgagt tgcacccatc atggtccgcc aagtttcgat tactttggga
     5761 ccagaaatga cacccacaag aactggacct gaagtcatga attcacgaat cggtgggtaa
     5821 aaactctgac caaccaagtc ctgatagtgc tggtcaatca actcttctga aacctgtgaa
     5881 cgaaactcca atttttcgat tgtaaatcca cgttgttcga tgcgctttaa cacttcaccc
     5941 actagccctc tttttacacc atctggtttg atgataaaga atgtttgttc catacccgtc
     6001 tcctttgtca gcttctttct tttat
//
LOCUS       DAVLHM010000077         5940 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLHM010000077 DAVLHM010000000
VERSION     DAVLHM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5940
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.077"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            67..309
                     /locus_tag="VXE45_002008"
     CDS             67..309
                     /locus_tag="VXE45_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0789985.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            311..565
                     /locus_tag="VXE45_002009"
     CDS             311..565
                     /locus_tag="VXE45_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0789986.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHWRDIY"
     gene            612..1264
                     /locus_tag="VXE45_002010"
                     /pseudo
     CDS             612..1264
                     /locus_tag="VXE45_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1524..2510)
                     /locus_tag="VXE45_002011"
     CDS             complement(1524..2510)
                     /locus_tag="VXE45_002011"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0789987.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2704..5172
                     /gene="gyrA"
                     /locus_tag="VXE45_002012"
     CDS             2704..5172
                     /gene="gyrA"
                     /locus_tag="VXE45_002012"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0789988.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5172..5915
                     /gene="srtA"
                     /locus_tag="VXE45_002013"
     CDS             5172..5915
                     /gene="srtA"
                     /locus_tag="VXE45_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0789989.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         1869 a          977 c         1295 g         1799 t
ORIGIN      
        1 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
       61 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
      121 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
      181 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
      241 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
      301 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
      361 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
      421 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
      481 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
      541 tggtcattgg agagatattt attgaattaa agctgagtaa taacagtata gaaagtaagg
      601 atagtaaaaa tttgaataaa aaatggttat ttgcagatta ttatgatata acaattattt
      661 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
      721 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
      781 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
      841 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
      901 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
      961 caggtaaatt agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     1021 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     1081 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     1141 atattgttcc agtttccctt tttgggaaga cgaattatcg agccaaagaa tattaataga
     1201 gaaacaatcc gagaagatag aagaactgca tcggatgata caagatttgc ttgaaaaaac
     1261 ataataaaaa taaagatgag acaaagtttg agttgaggag aaatcaagta agttttgaca
     1321 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaatga
     1381 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
     1441 atggggggct atttcaactt caacctacta taatacagaa aaaaacaact ccctgataat
     1501 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tgggtttttc
     1561 catgcttcgt caatgatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
     1621 gcgtcgttca atgggatatt tactggacga acaataccat gtgcaccaac aacagctggt
     1681 tgaccgataa agacgttctc aactccgtat tgaccttctt ggaatactga aagtggaagt
     1741 actgcatttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
     1801 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
     1861 aattcaatca attcagcttc ttgaacattt tgagtatctt taaggaattc ttcaaggttt
     1921 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
     1981 atgtaggcgt gaactgaacg agcatctacg tccaattttt cagcaagtgc ttgacggaaa
     2041 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
     2101 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
     2161 aaacctgatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
     2221 aggtcaagac gagtttcacc tggtttttga ggcgcacctg cagtgatcac aacaaggtca
     2281 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
     2341 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
     2401 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
     2461 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
     2521 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
     2581 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
     2641 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
     2701 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
     2761 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
     2821 aaacctgttc accgtcgcat tctttacgga atgaatgaat tgggtgtgac cccagacaaa
     2881 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
     2941 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
     3001 cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc cgctcaacgt
     3061 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
     3121 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
     3181 cgttttccaa accttttggt taatggagca actggtatcg cggttgggat ggcaaccaat
     3241 attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat ggataatcct
     3301 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
     3361 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
     3421 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgcat cgttgtaaca
     3481 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
     3541 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
     3601 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
     3661 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
     3721 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
     3781 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
     3841 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
     3901 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
     3961 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
     4021 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
     4081 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataag
     4141 cgccgtacag agttgatgat tggacaggtc ttgagtctcg aggatgagga cttgattgaa
     4201 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
     4261 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
     4321 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
     4381 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
     4441 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
     4501 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
     4561 gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
     4621 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
     4681 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
     4741 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
     4801 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
     4861 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
     4921 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
     4981 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
     5041 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
     5101 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa cgaaacagaa
     5161 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
     5221 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
     5281 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
     5341 aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
     5401 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
     5461 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
     5521 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
     5581 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
     5641 tagataatgc taaaaatggc atgaagattt atctaactga taaaaataaa gtttatactt
     5701 atgaaatacg tgaagtcaaa cgtgtgacac cagatcgtgt tgatgaagtt gatgatagag
     5761 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
     5821 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat gaaatcctaa
     5881 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
//
LOCUS       DAVLHM010000078         5939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLHM010000078 DAVLHM010000000
VERSION     DAVLHM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.078"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            411..632
                     /locus_tag="VXE45_002014"
                     /pseudo
     CDS             411..632
                     /locus_tag="VXE45_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(919..1401)
                     /locus_tag="VXE45_002015"
     CDS             complement(919..1401)
                     /locus_tag="VXE45_002015"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0789990.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(1496..2980)
                     /locus_tag="VXE45_002016"
     CDS             complement(1496..2980)
                     /locus_tag="VXE45_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0789991.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3133..4740
                     /locus_tag="VXE45_002017"
     CDS             3133..4740
                     /locus_tag="VXE45_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0789992.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            4905..5072
                     /locus_tag="VXE45_002018"
     CDS             4905..5072
                     /locus_tag="VXE45_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV0789993.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(5065..5586)
                     /locus_tag="VXE45_002019"
                     /pseudo
     CDS             complement(5065..5586)
                     /locus_tag="VXE45_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1752 a         1117 c         1322 g         1748 t
ORIGIN      
        1 aactggttcc ttttgaggta cgacgggcat gtcgtatagt aggttgaaac tagaatagta
       61 cacatctact tctaaaacat ttttagaaat cgatttgact gtcctgatcg atttgtcctg
      121 ttcttatttc attttactat atatctgagg tgtaagtcct cggtgggcac ctgttaccgg
      181 tgaacccaat agcgattccc aagcctgact atcgtgaggt agcggattaa aacggtctgg
      241 ggatagaccg ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa
      301 ctcgtggctc tacgaacagg aacgtgatag taaggcgtat atagcggata agggggcctc
      361 aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg taaatcacga gagcaactga
      421 atttgtccat tcgaggatgg ataaactatt tttcattggg aaatatgaaa agtatagtca
      481 ccagcataga tgagcgtttg catactcgcc tacgagtgat tatctggaag caatggaaga
      541 agaaatcgag acgattatgg ggattgctta agttaggggt tcctaaatgg atagcagata
      601 aggtatctgg ctggggcgac cactatcaat tatagtaaaa tgaaataaga atagaacaaa
      661 tcgatcagga tagtcaaatc gatttctaac aatgttttag aagcagaggt gaactattct
      721 agtttcaatc cactatagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag
      781 tccttgaaaa acgtggattg gtttcgtgtt tggattatta ccttgaacga catgcgttaa
      841 aaagttagtt gaaccgccgt atgccgaacg gtacgtacgg tggtgtgaga ggggctagag
      901 attatcccct actcgatttt aaatcacatg acgttcaaag gcatcatctg aaatcccttg
      961 ttccaagatg agttttgccc attctttagc agagaagagg ctgtggtcct tgtagtttcc
     1021 gcaagattcg atggttgtcc ctgggacatc ttcccaagta gtagtttcag cgatttcctt
     1081 gagcgaatcc ttgataacag ctgcgatttt agcactggtg tgacgtcccc acataatcat
     1141 gtggaagcct gtgcggcaac caaatggtga acagtcaatc atgccgtcaa tgcgggtacg
     1201 gatgagtttg gctaagaggt gctcgatagt gtgaaggccg gcagtaggga tagagtcttc
     1261 gtttggttgc accaagcgaa tatcataatt ggagatgatg tctccttttg gtcctgtttc
     1321 ttccccaatc aagcgaacat agggtgcttt gacaatggtg tggtcaagtt caaaactttc
     1381 gacaataact tcttttgaca tggtaaatcc tttcagtttt cttctctcat tatatcataa
     1441 aggttgctcc tgagacagag agaaaacctc tccgaggctg gagaggttga aatctttact
     1501 tacgatataa gcggtcgtat tggtagtatg ggtcaaaggt tacgttgata cccagtttac
     1561 gaaggacatt cttgtcttca tcagtcaaga tgatggttga gtgggcttcg cttcctttga
     1621 ggttgccgag ttcttccata gcgcgggcag catcaggatt ttctgtagct gtgatagcaa
     1681 gtgcaatcag gatttcattt gaatgaaggc gtggattgcg gctaccgaga tgatcgattt
     1741 taagaccttg gattggctta acaacttcag gctcgattag ttttacttct ttagcgatgt
     1801 cagctgattt tttgatggcg ttgatcaagg cagcggctgt aggcccaaag agttctgagt
     1861 tcttaccagt gacgatttcc ccatttggca attcaaaggc tagggctggt ccaccagttt
     1921 cttctgcttt ttggcgcgca acgacagcaa ccttacggtc tgcaggtgtg ataccgaggt
     1981 cgttcatgag caactcaatt ttcttgacgg cagcttcgcc aactttttca gctttgaagt
     2041 caagaactgt ttgatagtaa cggcggatga tttcttgttt agaagcttcg acagcagcct
     2101 cgtcatctgt aatagcgaaa ccaaccatgt tgacacccat atctgtcggt gaagcgtatg
     2161 gtgattttcc gagaatacgt tccaacatgc gcttgagcac tgggaagatt tcgatatcac
     2221 ggttgtagtt gacagtggtt tctccatagg tttgaagatg gaaggggtca atcatgttga
     2281 catcatcaag gtcagctgtg gcagcttcat aagccaagtt aactggatga tgaaggggaa
     2341 gattccaaac agggaaggtt tcaaatttag cgtagccaga cttgatgcca ttgatttggt
     2401 cgtggtacat attggacata cacgttgcca attttccaga accgggtcca ggagcggtta
     2461 cgacaatcaa gttgcgactg gttttgatgt agtcgttttt gcccatgcct tctggggaaa
     2521 tgatgtgatc catatccgtc ggatatcctt tgattggata atgaagataa gaatcaattc
     2581 cgtttttctc aagttggttg cggaaggcat ctgcagcgag ttggccagcg tattgtgtaa
     2641 tgacaacgga accaacaaaa atccctaatt cattgaattt gtcaatcaaa cgaagaactt
     2701 cttggtcata agaaatgcct aagtcgccac gtgctttgga atgttcaatg ttgctagcat
     2761 taatggcaat cacaacctca acctgctctt tcaattcttg caagagcttg attttgttgt
     2821 caggttcata accaggaagg acacgagcag cgtggaaatc ttctaacatt ttaccgccaa
     2881 actctaagta gagcttgccg tcaaattggt taatgcgctc taagatgtgg tcgcgttgta
     2941 aattcaaata ctgttcagaa ctaaaagctt gttttttcat ttttttacct ctggattcta
     3001 ttataataaa aaattggaag ttaggaaact acggagctaa aaaagaaatt aaaaagatta
     3061 agcaaacgct tgcacaaaat tttaaaaagt gctatcatat actatagatt attaaaataa
     3121 tgaggtaaac agatgcaaga aaaatggtgg cataatgccg tagtctatca agtctatcca
     3181 aagagtttta tggatagtaa tggagatgga gttggtgatt tgccaggtat taccagtaag
     3241 ttggactatc tagctaagct aggaatcaca gcgatttggc tttctcccgt ttatgacagc
     3301 cctatggatg ataatggcta tgatattgct gattatcaag cgattgcggc tatttttgga
     3361 accatggagg acatggatga actgattgca gaagctaaga agcgtgatat ccgtatcatc
     3421 atggacttgg tggtcaatca tacctcggat gagcatgcct ggtttgtaga ggcctgtgaa
     3481 aatcctaata gccctgagcg agactactat atctggcggg atgagcctaa cgatttagat
     3541 tctatcttta gtgggtctgc ttgggaatac gatgaaaagt caggtcaata ctatctccac
     3601 tttttcagca agaaacagcc ggatctcaac tgggaaaatg aaaaacttcg ccagaaaatt
     3661 tatgagatga tgaacttctg gattgataag ggtattggtg gtttccgtat ggatgttatt
     3721 gacatgattg gcaaaattcc tgacgagaag gtagtcaata atggtcctat gctccatccc
     3781 tatctcaagg aaatgaatca ggcgaccttt ggagataagg atctcttgac agtaggggag
     3841 acttggggag caacgccaga gattgccaaa ctctactctg atccaaaggg gcaagaattg
     3901 tctatggtct tccagtttga acatatcggt cttcagtatc aggaaggtca acctaaatgg
     3961 cactatcaaa aagagctgaa tatcgctaag ttaaaagaaa tcttcaacaa atggcagaca
     4021 gagttaggag ttgaggacgg ctggaattcc ctcttctgga acaaccatga cctccctcgt
     4081 attgtctcaa tctggggaaa tgaccaagaa taccgcgaaa aatctgccaa agcctttgca
     4141 atcttacttc atctcatgag aggaactcct tatatctacc aaggtgagga gattgggatg
     4201 accaactatc cgtttgaaac actggatcaa gtagaagata ttgaatctct caactatgcg
     4261 cgtgaggctc ttgaaaaagg tgttccgatt gaagaaatca tggacagtat ccgtgttatt
     4321 ggacgtgaca atgcccgtac ccctatgcaa tgggacgaga gcaaaaacgc tggtttctca
     4381 acaggtcaac cttggttggc agttaatcca aattacgaga tgatcaacgt ccaagaagcg
     4441 ctggcaaatc cagattctat tttctatacc tatcagaaac tggtccaaat tcgcaaggag
     4501 aatagctggc taattcgagc tgactttgaa ttgcttgata cggctgataa ggtctttgct
     4561 tatatacgta aggatggcga ccgtcgcttc ctagttgtgg ctaacttgtc caatgaagag
     4621 caagacttga cagtagaagg aaaagtcaaa tctgtcttga ttgaaaacac cctagctcaa
     4681 gaagtctttg aaaaacaaat cttagttcca tgggatgctt tctgtgtgga attactataa
     4741 atattttttg cagaaaaatt taaaattgaa atcgtataaa aacaagggag gactgtataa
     4801 aaggcagaaa tcctttgttt tttataacca aggtttataa accttcattc tcgaaattca
     4861 attaacttta caaattccca ctattaagga gaaagaagac gaacataaag aagcgtatcc
     4921 ttagtgcagg cctgactttt acatctgctt tgcttttagc tgcttgcgac caatcaggtt
     4981 cagatacaaa aacttactca tcaaccttta gtggaaatcc aactacattt aactatctat
     5041 tagactatta cgctgataat atagtcaatt gaaacaagaa caagacaaaa gagcctcata
     5101 aaaggtattg caacttggta ataccttttt gaggtgcttt ttgatatgag cccatgtttt
     5161 ctcaatagga ttgtactcag gtgagtaggg aggaagaggt aaaagtttat gcccaaactc
     5221 ttcgcataaa agttctagct tccccattct atggaatctt gcattatcca taataataac
     5281 cgatggtgtg gttaatgttg gtaagaaaaa cttctgaaac catacttcaa aaaagtcgct
     5341 cgtcatcatc tcttcgtaag tcattggagc gattaattca ccatttgtta gacctgcaac
     5401 caaagaaatc ctctgatatc ttcttccaga tactttgcct cttcttaact gaccttttaa
     5461 tgagcgacca tattctcgat aaaaataagt atcgaatcct gtttcatcaa tctaaacagg
     5521 tgctaggtgc tttaaactat taaaattctt aagaaataag gctacttttt ctgggtcttg
     5581 ttcataatta gattgaaact agagtagtag acctctgctt ctaaaacatt gttagaaatc
     5641 gatttgactg tcctgatcga tttgtcatgt tcttatttca ttttactata tttttgtttc
     5701 gcgggaagtc tactaagata cttaaagatg cagatagtaa aaaaaatgtg tcaatcgaaa
     5761 gtgattatgt ccccaaaaaa tggagagttt gagggcaatt attttgattt catttgacac
     5821 gaggaaccct tgaagctgtt ttgttagcta aaccaaggct agtcttagcc ttggctcgcc
     5881 agcctaacag ctccaagcct cttatcaaat gaaatacttg tcttacactc ctcactttc
//
LOCUS       DAVLHM010000079         5899 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLHM010000079 DAVLHM010000000
VERSION     DAVLHM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.079"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            109..1809
                     /locus_tag="VXE45_002020"
     CDS             109..1809
                     /locus_tag="VXE45_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0789994.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            1802..2278
                     /gene="ilvN"
                     /locus_tag="VXE45_002021"
     CDS             1802..2278
                     /gene="ilvN"
                     /locus_tag="VXE45_002021"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0789995.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            2344..3366
                     /gene="ilvC"
                     /locus_tag="VXE45_002022"
     CDS             2344..3366
                     /gene="ilvC"
                     /locus_tag="VXE45_002022"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0789996.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            3473..3709
                     /locus_tag="VXE45_002023"
     CDS             3473..3709
                     /locus_tag="VXE45_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0789997.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            3947..4303
                     /locus_tag="VXE45_002024"
     CDS             3947..4303
                     /locus_tag="VXE45_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0789998.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            4353..5603
                     /gene="ilvA"
                     /locus_tag="VXE45_002025"
     CDS             4353..5603
                     /gene="ilvA"
                     /locus_tag="VXE45_002025"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0789999.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
BASE COUNT         1822 a         1000 c         1347 g         1730 t
ORIGIN      
        1 taaacgttaa aatagaaaat tcagaaaatt tcttctttta tcttgaaaaa ttttgaaaaa
       61 atggtatgat agtaacaagt tatttttaag aggaaagaaa ggggaacaat ggagaaaatc
      121 agtttagaat ctcctaagac ggggtcggac ctagttttgg aaacacttcg tgatttagga
      181 gttgatacca tctttggtta tcctggtggt gcggttttgc ctttttatga tgcgatatat
      241 aattttaaag gcattcgcca cattctaggg cgccatgagc aaggttgttt gcatgaagct
      301 gaaggttatg ccaaatcaac tggaaagttg ggtgttgccg tcgtcactag tggaccagga
      361 gcaacaaatg ccattacagg gattgcggat gccatgagcg atagcgttcc ccttttggtc
      421 tttacaggtc aggtggcgcg agcagggatt gggaaggatg cctttcagga ggcagacatc
      481 gtgggaatta ccatgccaat cactaagtac aattaccaag ttcgtgagac agctgatatt
      541 ccgcgtatca ttacggaagc tgtccatatc gcaactacag gccgtccagg gccagttgta
      601 attgacctac caaaagatat atctgcttta gaaacagact tcatttattc accagaagtg
      661 aatttaccaa gttatcagcc gactcttgag ccgaatgata tgcaaatcaa gaaaatcttg
      721 aagcaattgt ccaaggctaa aaagccagtc ttgttagctg gtggtggaat tagttatgct
      781 gaggctgcta cggaactaaa tgaatttgca gaacgctatc aaattccagt ggtaaccagt
      841 cttttgggac aaggaacgat tgcaacgagt cacccactct ttcttggaat gggaggcatg
      901 cacgggtcat tcgcagcaaa tattgccatg acggaagcgg actttatgat tagtattggt
      961 tctcgtttcg atgaccgttt gacggggaat cctaagactt tcgctaagaa tgctaaggtt
     1021 gcccacattg atattgaccc agctgagatt ggcaagatta tcagtgcaga cattcctgta
     1081 gttggagatg ctaagaaggc cttgcaaatg ttgctagcag aaccaacagt tcacaacaac
     1141 actgaaaagt ggattgagaa agtcactaaa gacaagaatc gtgttcgttc ttatgacaag
     1201 aaagagcgtg tggttcaacc gcaagcagtt attgaacgaa ttggtgaatt gacgaatgga
     1261 gatgccattg tggtaacaga cgttggtcaa caccaaatgt ggacagctca gtattatccc
     1321 taccaaaatg aacgtcagtt agtgacttca ggtggtttgg gaacaatggg ctttggaatt
     1381 ccagcagcaa tcggtgctaa aattgctaac ccagataagg aagtagtctt gtttgttggg
     1441 gatggtggtt tccaaatgac caaccaggag ttggctattt tgaatattta caaggtgcca
     1501 atcaaggtgg ttatgctgaa caatcattca cttggaatgg ttcgccagtg gcaggaatcc
     1561 ttctatgaag gcagaacatc agagtcggtc tttgataccc ttcctgattt ccaattgatg
     1621 gcgcaggctt atggtattaa aaactataag tttgataatc ctgagacctt ggctcaagac
     1681 cttgaagtca tcactgagga tgttcctatg ctaattgagg tagatatttc tcgtaaggaa
     1741 caggtgttac caatggtacc ggctggtaag agtaatcatg agatgttggg ggtgcagttc
     1801 catgcgtaga atgttaacag caaaactaca aaatcgttca ggagtcctca atcgctttac
     1861 aggtgtccta tctcgtcgtc aggttaatat tgaaagcatc tctgttggag caacagaaga
     1921 tccgaatgta tcgcgtatca ctattattat tgatgttgct tctcatgatg aagtggagca
     1981 aatcatcaaa cagctcaatc gtcagattga tgtgattcgc attcgagata ttacagacaa
     2041 gcctcatttg gagcgcgagg tgattttggt taagatgtca gcgccagctg agaagagagc
     2101 tgagatttta gcgattattc aacctttccg tgcaacagtg gtagacgtag cgccaagctc
     2161 gattaccatt cagatgacgg gaaatgcaga aaagagcgaa gccctattgc gagtcattcg
     2221 cccatacggt attcgcaata ttgctcgaac gggtgcaact ggatttaccc gcgattaaaa
     2281 atccaactta aatttattaa accagcctaa aaggcaataa ataatagaaa agagagaaaa
     2341 gctatgacag ttcaaatgga atatgaaaaa gatgttaaag tagcagcact tgacggtaaa
     2401 aaaatcgccg ttatcggtta tggttcacaa ggacatgcgc atgctcaaaa cttgcgtgat
     2461 tcaggtcgtg acgttattat cggtgtacgt ccaggtaaat cttttgataa agcaaaagaa
     2521 gatggatttg atacttacac agtagcagaa gctactaagt tggctgatgt tatcatgatc
     2581 ttggcgccag acgaaattca acaagaattg tacgaagcag aaatcgctcc aaacttggaa
     2641 gctggaaacg cagttggatt tgcccatggt ttcaacatcc actttgaatt tatcaaagtt
     2701 cctgcggatg tagatgtctt catgtgtgct cctaaaggac caggacactt ggtacgtcgt
     2761 acttacgaag aaggatttgg tgttccagct ctttatgcag tataccaaga tgcaacagga
     2821 aatgctaaaa acattgctat ggactggtgt aaaggtgttg gagcggctcg tgtaggtctt
     2881 cttgaaacaa cttacaaaga agaaactgaa gaagatttgt ttggtgaaca agctgtactt
     2941 tgtggtggtt tgactgccct tatcgaagca ggtttcgaag tcttgacaga agcaggttac
     3001 gctccagaat tggcttactt tgaagttctt cacgaaatga aattgatcgt tgacttgatc
     3061 tacgaaggtg gattcaagaa aatgcgtcaa tctatttcaa acactgctga atacggtgac
     3121 tatgtatcag gtccacgtgt aatcactgaa caagttaaag aaaatatgaa ggctgtcttg
     3181 gcagacatcc aaaatggtaa atttgcaaat gactttgtaa atgactataa agctggacgt
     3241 ccaaaattga ctgcttaccg tgaacaagca gctaaccttg aaattgaaaa agttggtgca
     3301 gaattgcgta aagcaatgcc attcgttggt aaaaacgacg atgatgcatt caaaatctat
     3361 aactaattag aaatatatag cgctggagat gattttatga aaaagattat gagaaaaact
     3421 gcatcgttat tattggttct agttgtataa tgtaattaca ccgtcggtaa tagtgctagc
     3481 agaccaaaat aaagcagatt ggtcgtatga tgaaaatgct gtaattaaca tttatgatga
     3541 tgctaatttt gaagatggta ggttgcatat gaactttgaa caattcttca aattggcaca
     3601 aatatctaga gaagaaggtc ttgaaattca ttctccgttt gagagagctg gtgcgactaa
     3661 atctgctcgt tatatagcga aatggatttt gagaaataaa aaacattaac aaatatagtt
     3721 ggtaaatcat taggacctaa atcagctgtt agattcggag aagctttatc ctatattgaa
     3781 ggtcctcttc gcagaataaa tgagacgata gatggcggtt tatatcaaat agagcaaatt
     3841 attgcatctg gattgaaaga atcgggttta aatgactgga ctgcgaaaac tttagcttca
     3901 gctattcgtg ggatattaga tgtacttatt taggggttga aatcatatga atattaccaa
     3961 tttgttttct atcaagacag gatgtgatga aactgatagg caactgcaaa aactattttt
     4021 tcagttggat ttacaattgg gagaattgac agatcaacta agaaaattag attctaattt
     4081 tgttcctcgt agtcaatttg tagacacgtt ggatttgaat gatgtagaat ataaagaaat
     4141 tttaaactat tttatcttcc atcgtaatga tagtgaagaa agtttggtag aatggttata
     4201 tgattggatt tccacaaatc gttatgaact tcctaaagag ttttcgattc gtatggctca
     4261 taaataccat gaaagtgtta ctgaagtttt cggagatgaa taactaaaaa acagtcatta
     4321 gtgactgttt tttatagaaa aagaggtttt atatgttaag ttcaaaagat ataatcaagg
     4381 ctcacaaggt cttgaacggt gtggttgtga atactccact ggattacgat cattatttat
     4441 cggagaagta tggtgctaag atttatttga aaaaagaaaa tgcccagcgt gttcgctcct
     4501 ttaaaattcg tggtgcctat tatgccattt cccagctcag caaggaagaa cgtgaacgtg
     4561 gggtagtctg cgcttctgcg ggaaatcatg cgcagggagt agcctatact tgtaatgaaa
     4621 tgaaaattcc tgctactatc tttatgccca ttactacgcc acaacaaaag attggtcagg
     4681 ttcgcttttt tggtggggat tttgtaacta ttaaactagt tggagatacc tttgatgcct
     4741 cagccaaagc agctcaagaa tttacagtct ctgaaaatcg tacctttatt gatccttttg
     4801 atgatgctca tgttcaagca ggtcaaggaa cagttgctta tgagatttta gaagaagctc
     4861 gaaaagaatc gattgatttt gatgctgtct tggttcctgt tggtggtggc ggtctcattg
     4921 ccggggtttc tacctatatc aaggaaacaa gtccagagat tgaggttatc ggagtagagg
     4981 cgaatggagc gcgttccatg aaagctgcct ttgaggctgg aggtccagtc aaactcaagg
     5041 aaattgataa atttgcggat gggattgctg tgcaaaaggt aggtcagttg acctatgaag
     5101 caactcgtca acatattcaa actttggtag gtgtcgatga gggattgatt tctgaaacct
     5161 tgattgacct ttactctaag caagggatag tcgcagaacc tgctggagca gctagtatcg
     5221 cctctttaga ggttttagct gaatatatta aggggaaaac catttgttgt atcatttctg
     5281 gaggaaataa tgatatcaac cgtatgccag aaatggaaga gcgtgccttg atttatgatg
     5341 gtatcaaaca ttactttgtg gtcaatttcc cacaacgtcc aggagctttg cgtgagtttg
     5401 taaatgatat cctggggcca aatgatgata tcacacgttt tgagtatatc aaacgagcta
     5461 gcaagggaac aggcccagta ttaattggga tcgctttagc agataagcat gattatgcag
     5521 gtttgattcg tagaatggaa ggttttgatc cagcttatat taacttaaat ggtaatgaaa
     5581 cgctttataa tatgcttgtc tgaggactaa taaaaaaata tcatattatt tgtacaactg
     5641 atgtatatgt gctataatga agatgaagaa aggggacgat tcctatggtt ttagaaaact
     5701 tatcgtgcaa ttcttacttc tgttcattat agcacttatg atgtttggct cagatttcca
     5761 tccttcattt tgatttccta tctattgaca agcatagtca cactgtcttt aatactcttc
     5821 gaaaatctct tcaaaccacg ttagctctat ctgcaacctc aaaacagtgt tttgagcaac
     5881 ttgcggctag cttcctagt
//
LOCUS       DAVLHM010000080         5589 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLHM010000080 DAVLHM010000000
VERSION     DAVLHM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.080"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            161..1191
                     /locus_tag="VXE45_002026"
                     /pseudo
     CDS             161..1191
                     /locus_tag="VXE45_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1188..1406
                     /locus_tag="VXE45_002027"
     CDS             1188..1406
                     /locus_tag="VXE45_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790000.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(1463..1747)
                     /locus_tag="VXE45_002028"
     CDS             complement(1463..1747)
                     /locus_tag="VXE45_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0790001.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(1801..2736)
                     /locus_tag="VXE45_002029"
     CDS             complement(1801..2736)
                     /locus_tag="VXE45_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0790002.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            2840..3283
                     /locus_tag="VXE45_002030"
     CDS             2840..3283
                     /locus_tag="VXE45_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0790003.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSIGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            3399..3665
                     /locus_tag="VXE45_002031"
     CDS             3399..3665
                     /locus_tag="VXE45_002031"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0790004.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3662..4036
                     /gene="crcB"
                     /locus_tag="VXE45_002032"
     CDS             3662..4036
                     /gene="crcB"
                     /locus_tag="VXE45_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0790005.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            4030..4359
                     /gene="crcB"
                     /locus_tag="VXE45_002033"
     CDS             4030..4359
                     /gene="crcB"
                     /locus_tag="VXE45_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0790006.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4478..4825
                     /gene="rplS"
                     /locus_tag="VXE45_002034"
     CDS             4478..4825
                     /gene="rplS"
                     /locus_tag="VXE45_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0790007.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4867..4938
                     /locus_tag="VXE45_002035"
     tRNA            4867..4938
                     /locus_tag="VXE45_002035"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4900..4902,aa:Arg,seq:cct)
BASE COUNT         1704 a          972 c         1167 g         1746 t
ORIGIN      
        1 aaagtatggt atgctataag aaaagaaaat gtttagcaat tcagaaatca cttgttaatt
       61 tatccgtgat atgttagatt tgctagtaaa attatgacca ttttggagga aagcaatatt
      121 tataccagac taaaatcaaa aagcattata taatagtgat atgaaatcaa ctaaagaaga
      181 aatccaagcc atcaaaacac ttttaaaaga ctctcgtaca gctaaatatc ataaacgcct
      241 tcaaatcgtt ctatttcgtc tgatgggcaa atcttataaa gagattatag agcttttaga
      301 ctgtaatcaa acaacgattt ggcgaaatgt aaaaaaatat gaggagttcg gactcgactc
      361 tctccttcaa gaaacacgtg gtggtcgtaa ccatgcatat atgacagttg aggaagagaa
      421 agcctttctt gcccgccatt tgaaggctac agaggcagga gaatttgtta caatacctta
      481 tttcaggctt atatcgttcc tacacacgtg atgccttcta tcaactgttg aagcgccatg
      541 gttggcgaaa tattatgcca cgtccagaac atcctaagaa agcagacgct caaaccattg
      601 tcgcgtctaa aaataaaatc tcaattcaag aagaaaagaa agcgctttaa aaccagtaga
      661 ccttttcata aggttcgctc gatgtaccaa gatgaggctg gtttcggtag aatcagtaaa
      721 ctgggatctt gttggtctcc aataggagta ggtccacatg tccatagtca ctatatacga
      781 gaatttcgct attgttatgg agctgttgat gcccatacag gcgaatcatt tttcttaaga
      841 gctggtggat gtaatactga gtggatgaac gcctttttag aagagctttc acaagcttat
      901 ccagatgatt atcttttact cgttatggac aatgctatat ggcataaatc aagtacctta
      961 aagattccga ctaatattgg ctttgcattt attcctccgt acacaccaga gatgaacccc
     1021 attgaacaag tgtggaaaga gattcgtaaa cgtggattta aaaataaagc ctttcaaact
     1081 ttggaagatg tcatgaatca actttaagat atcatacaag gactggagaa ggaggtgata
     1141 aagcccatcg ttaatcggag atggactaga atgctttgtg aaagcagatg agtataagtc
     1201 ctcgttttga aaccttagag caggccattg cctccaaaga tttggaaaaa gtccgagaag
     1261 cttttaagaa aatgaattcc acttggacca tcaatgaaag tgtggttcgt gacaatagta
     1321 cagctcatta tggacgtgtt gaaacagcta tttccttcct gcctagtagc atggaaacca
     1381 aacctacaga tgagtctgga acatgaaaac agcagttgat ttcaagaaac aaaaaagaac
     1441 agccgaaact gttctcttat cattatttga gaccgtattt tttgttgaaa cgatccacgc
     1501 gtccatctgc ttgagtgaac ttttgacgtc cagtgtagaa tgggtgtgag tctgatgaaa
     1561 tttccacacg gatcaatggg taagtttcgc cttcgaactc aactgtttcg ttagagcgtt
     1621 ttgttgaacc gctaaggaat tggtaaccag tagttgtgtc catgaagaca actgggcgat
     1681 attctggatg gatatctttt ttcattttgc aatatttcct ttctgccatg gtctctttgc
     1741 gagccataga ttgttaccat actagtctat cagattctga aaagtttggc aagtatttta
     1801 tcagttttta agcaagtttt ttaacttttg gtagatgatt tcgttttctt ctaggctata
     1861 ggaattagca ccacttgcta gagggtggcc tccaccatca tgctccttgg cgatttcatt
     1921 gataggatgg attttactgc gtaagcgaac tcggtagtgg ccatcagcct gttcgacaaa
     1981 aattccccag agactcactc tgtcaatgcg tccaggtgca ccgacaatgg ctgcagtttc
     2041 agcatcggtt acattgtatt gtttcaagac ttcttgactc aggataacgc gagcagcacc
     2101 attttcatcc acttccagat ggtcgtagat gtagccttgc agtttagcaa ttttgtagct
     2161 catagtgtcc attttgcgag tgagagccgc aaagtcaaag ttatgttctc tcaaataagc
     2221 agccaggcga agagtccgtg cagtggtaga agggtagagg aagcgacctg tatcaccgac
     2281 aattcctgca aagagcaact cagcatcgcg atctgccaag gctagttggg ttgtttgggc
     2341 aaatagggta atcatctcgc tagcgctact tgaactagta tcgacccaag acaggtcacc
     2401 gtatacatca tcatttggat ggtggtcaat cttaatgaga aaatcacctt gactatagcg
     2461 cttatcatcg atacgagcag tattagctgt atcacagacg atgacaagtg cgccttggta
     2521 ggctctatct tcaacaagat ccatctcagc catccaagta agagttggtt catcaaaacc
     2581 gacggctttg atggtttttt ctgggaaatg atgttccagc aaggctttca atcccacctg
     2641 acttcccaag gcatcagggt ctggtttcat atgacgatga atgataatgg tgtcgtattc
     2701 tttaattttt tctaaaattt gttggcaaat ctccataaat aacctcaatt ctttctcatt
     2761 tcattgtagc acaagaattt ttatttttaa aatgaaaaag atgtgatata atggagaaag
     2821 ataaattgag gaggacgata tggcattagc aaaaattgta tttgccagta tgaccggtaa
     2881 taccgaagaa attgcagata ttgtagcaga caaattacgt gacttgggct tggatgttga
     2941 tgttgatgaa tgtacaactg ttgacgcttc agacttcttg gaagcagaca tcgctatcgt
     3001 tgcgacctat acttatggtg atggtgaatt gccagatgag atgatggact tctacgaaga
     3061 cctagcagat ctcaacttga atggcaaaat ctacggagtg gtcggctcag gagatacctt
     3121 ctacgatgaa ttctgtaagg ctgttgatga ctttgaccgt gtctttgtgt caataggagc
     3181 agaaaaaggt tcagagtgtg ttaaagttga tctttctgcc gaggaagaag atattgaacg
     3241 cttggaacaa ttcgcagaag aattggttgc taaagtagta taagcataaa agtgcgctga
     3301 tgtaatcaat cagtgcattt ttcttatcga gagttgggat tttactagcc taattgatgg
     3361 ctttttgata caataattca aataaaggag gagactgtat ggatttagat attattcgtc
     3421 aagaaatcga tcaaatcgat gaccaaattg tcaaactgtt agaagaacga atgcatttag
     3481 ttgagggggt ggttgcttat aagaaagctt caggtaaacc gattttagat actaagagag
     3541 aagaagttat ttttgaaaag gttaggagtc gtgtagagga caagcgctat caggagacta
     3601 ttgtagcgac tttttcggac atactcaaac gttcgcgtga ttatcaggat caaaatatca
     3661 aatgaaaaaa gaacaatttt atccgctagg aatttttcta gctgctatgt tgggcggact
     3721 tgtccgatat ctagtttcca cctggttacc agccagtcca gactttcctt ggggcactct
     3781 ctttgtcaac tatctgggaa ttttctgctt gatttttctt gtcaagggct atctggtcta
     3841 taaggggact agtaagggct tgattttagc actggggacg ggtttttgcg gaggtttaac
     3901 aactttttcc agcctaatgc ttgatactgt gaagctgctt gatacagggc gttatcttag
     3961 tttagtcctg tatttgcttt tgagcatcgg tggaggccta ctcttagctt attttctagg
     4021 gaggaagaaa tggtaatcgt ctatcttgca atcgcctgtg gcttgggagc actcgtacgg
     4081 tatttctttt cccgctacaa tcaagcttct aaattgccac tcggaacgct catagctaat
     4141 cttttaggtt gttttttaat tggagtattc tacaatcatg tagagtctaa ggaagtatat
     4201 gctattctag caacaggatt ttgtggcggt ttaacaactt tttcgacctt gaatgacgaa
     4261 cttcaaagac tgttaagtga taagaaggtc ttttattctt acctgacttt gacttacata
     4321 ggtggtttgg ttgcgatttt tttaggaatt ttgctataaa tttctttact tttttgtgaa
     4381 aatttggtag actgtatctt gtgtgtgatg gacgcacaaa aatacagttt atccgctgag
     4441 gaaatttcct caagattgac aaagatagga gaataaaatg aatccattaa tccaaagctt
     4501 gactgaaggt caacttcgta cagatatccc atcattccgt cctggtgaca ctgttcgtgt
     4561 acacgcgaaa gttgtcgaag gtaaccgtga acgtatccag atttttgaag gtgttgttat
     4621 cgcacgtaaa ggtgctggaa tctcagaaaa ctacacagtt cgtaaaatct ctaacggtgt
     4681 aggtgttgag cgtatcttcc caatccacac tccacgtgtt gaaaaaatcg aagttgttcg
     4741 ttacggtaaa gtacgtcgtg cgaaattgta ctacttgcgt gctcttcaag gtaaagcagc
     4801 tcgtatcaaa gaaatccgtc gttaattcga ctaaaaaact ctgcttttca gcagagtttt
     4861 tatctagctc ccttagttca atggatataa caactccctc ctaaggagta gttgcaggtt
     4921 cgattcctgc agggggcatt tttagtaatg taaagaaaga caaagaaaat tcaaaatgtt
     4981 tatttgaagg caattttctc aagttcattt ttaaaaataa tttagcattt ttaatttttt
     5041 tgaccaaatt ttgaccaaaa attatatttt ggtcaatgat tatagaataa aatggatcat
     5101 aaaaatgtct ttgatttata gtagtgctaa aaaggacttc ctttattgga atgtccttat
     5161 ttttattatg gaattgccaa atgacgttaa ggttcagttc tatgaactta gaaagaaagt
     5221 acaaagcttt aatcagcttt caaaaagatt tggtatggat gtttctggct aaggtatgtg
     5281 acaaggtgaa ttgatcgtta ttgaacagag agcgttaaaa aagggaagaa tcgttactat
     5341 tccactgaat taaaacaaga aataaatcaa caaaagccta tataataaca aatgtattaa
     5401 aaataaaaag atttagttca gtgtaatgca gaaccaaatc ttatggataa attatttgtc
     5461 taatttttta ggaattatat ctctaaacaa tatcatttaa caattaaatt gttagatcta
     5521 gcttaaattt ctggtttaat tcatttattg tgtcactatc attatattcc ttaaatattc
     5581 tcatagctt
//
LOCUS       DAVLHM010000081         4674 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLHM010000081 DAVLHM010000000
VERSION     DAVLHM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.081"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..832
                     /locus_tag="VXE45_002036"
                     /pseudo
     CDS             1..832
                     /locus_tag="VXE45_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(865..1205)
                     /gene="tnpB"
                     /locus_tag="VXE45_002037"
                     /pseudo
     CDS             complement(865..1205)
                     /gene="tnpB"
                     /locus_tag="VXE45_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            1448..2719
                     /locus_tag="VXE45_002038"
                     /pseudo
     CDS             1448..2719
                     /locus_tag="VXE45_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2828..3127)
                     /locus_tag="VXE45_002039"
     CDS             complement(2828..3127)
                     /locus_tag="VXE45_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0790008.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(3292..3743)
                     /locus_tag="VXE45_002040"
                     /pseudo
     CDS             complement(3292..3743)
                     /locus_tag="VXE45_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            3825..4479
                     /locus_tag="VXE45_002041"
                     /pseudo
     CDS             3825..4479
                     /locus_tag="VXE45_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            4567..4674
                     /locus_tag="VXE45_002042"
                     /pseudo
     CDS             4567..4674
                     /locus_tag="VXE45_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1548 a          804 c          909 g         1413 t
ORIGIN      
        1 cgtggtggtc gtaaccatgc atatatgacg gttgaggaag agaaagcctt tcttgcccgt
       61 catttgaagg ctgcagaggc aggagaattt gttacaattg atgccttatt tcaggcttat
      121 aaaaaggagt taggtcgttc ctacacacgt gatgccttct atcaactgtt gaagcgccat
      181 ggttggcgaa atattatgcc acgtccagaa catcctaaga aagcagacgc tcaaaccatt
      241 gtcgcgtcta aaaataaaat ctcaattcaa gaagaaaaga aagcgcttta aaaccagtag
      301 acgttttcat aaggtttgct tgatgtacca agatgaggct ggtttcggta gaatcagtaa
      361 actgggatct tgttggtctc caataggagt aggtctacat gtccatagtc actatatacg
      421 agaatttcgc tattgttatg gagctgttga tgcctataca ggcgaatcat ttttcttaat
      481 agctggtgga tgtaatactg agtggatgaa cgccttttta gaagagcttt cacaagctta
      541 tccagatgat tatcttttac tcgttatgga caatgctgta tggcataaat caagtacctt
      601 aaagattccg actaatattg gctttgcatt tattcctcca tacacaccag agatgaaccc
      661 cattgaacaa ttgttgaaag agattcgtaa acgtggattt aagaataaag cctttcgaac
      721 tttggaagat gtcatgaatc aactccaaga tgttatacaa ggactggaga aggaggtgat
      781 aaagtccatc gttaatcgga gatggaatag aatgcttttt gaaagcagat gagtataaaa
      841 agaaagtcct catttcaata gaaatcacga ctttctgatg gatttatttt tggagtgata
      901 gaaaagcccg tcataagcca gtctacttgt tcaggtgtga gagctttgac atccttttct
      961 gtattgggcc aagtcagtct gccgttctca aagcgtttat atagtagcca aaatccttga
     1021 ccatcccagt aaagggcttt aaagcggtct ttacgtccac cacaaaagag aaagacttga
     1081 ccggagaaag gatccaattc aaagtgggtt ttaactacat aggctaatga gtctattccc
     1141 tgcctcatat ctatcttgct acaaacaagg tgaacttgac ctaaatcact tagttgaatt
     1201 atcatagtac aatacctttc ctccgataat tattttttat ctagtatact ggaagttggg
     1261 gaattaggat agataccttg ttatgacgcg cttacgtaac ttgtaactag ctgcctagtt
     1321 tgatctttgc ttcttcattg attagcagta gatttcaaaa tgataaaaac gcataatagt
     1381 gggtgtagaa tgaactgcct tccaaaaagt tagacagaaa aaatctaact tttggggtgt
     1441 ttttattatg aaattaactt atgatgataa agttcagatc tatgaactta gaaaacaagg
     1501 atataactta gagaagcttt caaataaatt tgggataaac aattctaatc ttaggtatat
     1561 gattaaattg attgatcgtt acggaataga gttcgtcaaa aaaggaaaaa atcgttacta
     1621 ttctcctgat ttaaaacaag aaatgattca taaagtctga catgaaggct ggactaaaga
     1681 tagagtttct cttgaatacg gcctcccaag tcgtacgata cttcttaact ggctagcaca
     1741 atacaggaaa aacgggtata ctattgttga gaaaacaaaa gggagagtac ctgagagcgg
     1801 agaatgccat cctaaaaaag ttaagagaac tccgattgaa ggaggaaaaa gagaaagaag
     1861 aaagacagaa attgttcaag aattaatgac tgagttttcg ttagttcttc ttctaaaatc
     1921 cattaaacta gctcgttcga cctactacta tcacttgaaa cagctagaca aaacagataa
     1981 ggaccaagag cttaaagctg aaattcaatc catttttatc gaacacaagg gaaattatgc
     2041 ttatcgtcgg atttatttag aactaagaaa tcgtggttat ctggtaaatc ataaaagagt
     2101 tcaaggcttg atgaaagtac tcaatttaca agctaaaatg cgacagaaac gaaaatattc
     2161 ttctcataaa ggagacgttg gcaagaaggc agagaatctc attcaaggcc aatttgaagg
     2221 ctctaaaaca atgggaaagt gctatacaga tgtgacagaa tttgccattc cagcaagtac
     2281 tcaaaagctt tacttatcac cagttttaga tggctttaat agcgaaatta tcgcctataa
     2341 tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga
     2401 gaagcactac gagaatacga ttctccatag tgaccaaggc tggcaatatc aacacgattc
     2461 ttatcatcag tttcttgagg gtaagggaat tcaagcatcc atgtcacgta agggaaacag
     2521 ccaagacaac ggtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttatgg
     2581 ctatgagaaa acatttaaat cacttaatca attggaacaa gctattgtag actatattga
     2641 ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccttg tgcaatacag
     2701 aactaaatcc ttcggataaa ttatttgtct aactttttgg ggtcagtaca aaactcttgc
     2761 tactatgcgt tttgttatgg aaagacttat tggactttct ctcaaatcga gtttttactc
     2821 aattttctta cttgattggg attgaaattc caattaattt ctctgagtag agtgtcttga
     2881 tattggcttc atcaacagag gtcttatcaa ttttacgttt caagaaaaat tcttgaatgg
     2941 tttcgatttc aggctcacga atagcacggt gtttgtttga gatgaggatt tcatagtgaa
     3001 gcggagcttg ggtaaaaata acatctgtat tccctgcaga ataaacctca acaagggttg
     3061 catcggtact ttctagttga ctttttacaa gttgcgagtg tgagtttgtc gtattgataa
     3121 gcttcataat atttcctccg attttctaat tctattataa cactttttga ataaagtcgc
     3181 ttgatttata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggctatactt
     3241 gagtacggta aggcgacgct tacgtgattt gaattttatt ttcgaagagt attagccaat
     3301 cttatgctgt tttttccaag attcaatggc ccatttatgg ctaccacgtt taaggttttt
     3361 gatagcctcg tcaataggga accaggcaat atgattaaag ttttctagtg gcttttgtac
     3421 ttctttgaaa ggagttgctt catagaggta ggcaggattg tagtagtagg tatcacgatg
     3481 acgagaatag aaatattcgt cagcttgtcc gtaataggta ccaatttctg ctgtgaaacc
     3541 aagctcttca atcaactcac gctttagggc ttcctgatga ttttcacctg cttcaatttt
     3601 tccacatggt aggaaccaag caccatttgg ttcttgaaca agaacaattt gtttttgttc
     3661 aggattaggg ataactgcat atacgccata gcgagtaata tagtctgtat tcactttttt
     3721 tctccgaaag ttgggtttgc cattgcattt tcctcattat ctagtatcgt tattattata
     3781 gtgaaatgaa ccaaaaatag tacacaatgt ggtataatct ttttatggca tattcaatag
     3841 attttcgtaa aaaagttctc tcttattgtg agcgaacagg tagtataaca gaagcatcac
     3901 acgttttcca aatctcacgt aataccattt atggctggtt aaagctaaaa gagaaaacag
     3961 gagagttaaa ccaccaagta aaaggaacaa aaccaagaaa agttgataga gatagactta
     4021 aaaactatct tactgacaat ccagacgctt atttgactga aatagcttct gaatttggct
     4081 gtcatccaac taccatccac tatgcgttca aagctatggg ctacactcga aaaaaagaac
     4141 cacacctact atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaataga
     4201 ttaaagcacc tagcacctgt ttagattgac gaaacaggat tcgatactta tttttatcga
     4261 gaatatggtc gctcattaaa aggtcagtta agaagaggca aagtatctgg aagaagatat
     4321 cagaggattt ctttggttgc aggtctaaca aatggtgagt taatcgctcc aataacttac
     4381 gaagagacga tgacgagcga cttttttgaa gtatggtttc agaaatttct cttaccaaca
     4441 ttaaacacac catcggttat tatagtaaaa cgaaataaga ataggacaaa tcgatcagga
     4501 cagtaaaatc gaattctaac aatgttttag aagtagatgt gtactattct agtttcaatc
     4561 tactatatta tggataatgc aagattccat agaatgggga agctagaact tttatgcgaa
     4621 gagtttgggc ataaactttt acctcttcct ccctactcac ctgagtacaa tcct
//
LOCUS       DAVLHM010000082         4381 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLHM010000082 DAVLHM010000000
VERSION     DAVLHM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.082"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            30..1055
                     /locus_tag="VXE45_002043"
     CDS             30..1055
                     /locus_tag="VXE45_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0790009.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1045..2052
                     /locus_tag="VXE45_002044"
     CDS             1045..2052
                     /locus_tag="VXE45_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0790010.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2052..3059
                     /locus_tag="VXE45_002045"
     CDS             2052..3059
                     /locus_tag="VXE45_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0790011.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFVLLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3059..3853
                     /locus_tag="VXE45_002046"
     CDS             3059..3853
                     /locus_tag="VXE45_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0790012.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT         1585 a          636 c          744 g         1416 t
ORIGIN      
        1 tagacttgaa atatgtttaa ggagttttta tgaaaaacaa attttttcta atagctattt
       61 tagctatgtg tatagttttt agcgcttgtt cttctaattc tgttaaaaat gaagaaaata
      121 cttctaaaga gcatgcgcct gataaaatag ttttagatca tgctttcggt caaactatat
      181 tagataaaaa acctgaaaga gttgcaacta ttgcttgggg aaatcatgat gtagcattag
      241 ctttaggaat agttcctgtt ggattttcaa aagcaaatta cggtgtaagt gctgataaag
      301 gagttttacc atggacagaa gaaaaaatca aagaactaaa tggtaaagct aacctatttg
      361 acgatttgga tggacttaac tttgaagcaa tatcaaattc taaaccagat gttatcttag
      421 caggttattc tggtataact aaagaagatt atgacactct atcaaaaatt gctcctgtag
      481 cagcatacaa atctaaacct tggcaaactt tatggagaga tatgattaaa attgattcaa
      541 aagccttagg tatggaaaaa gaaggtgatg agttaatcaa aaatactgaa gctcgtatat
      601 ccaaagaatt agaaaaacat ccagaaatca aaggaaaaat caaaggaaaa aaagtattat
      661 ttactatgat taatgctgca gatacatcaa aattctggat ttatactagc aaagatccaa
      721 gagcaaatta tttaacagat ttaggtctag ttttccctga atcattaaaa gaatttgaga
      781 gtgaagatag ttttgcaaag gaaatttctg cagaagaagc aaataagata aatgatgctg
      841 atgtaatcat aacttatggt gatgataaaa ctcttgaagc tttacaaaaa gatcctcttt
      901 taggtaaaat aaatgcaatt aaaaatggtg ccgttgctgt aattccagat aatacaccgt
      961 tagcagcctc atgcactcca acaccacttt caataaacta tactattgaa gaatacctaa
     1021 atcttttagg aaatgcatgc aaaaatgcga aataaaaaac aaataaacct aggcataatt
     1081 tttgtaatct gcctaggtct tcttattaca atatttttgt cattaaagct tggaacaaaa
     1141 gaaattaata tcagagattt tttagcagct tttggaatgg gtaatacaaa tgatgatttt
     1201 attaaatcaa ttatatataa aagaatacct agaactattt ttgcaatttt agcaggttct
     1261 agtcttgcca taagcggtgt attgatgcaa tcagttacta gaaacccaat agctgatcca
     1321 ggtatactcg gtataaacac aggagcaagt cttagtgtag taattggtct ttctttttta
     1381 ggaatttcat caagcataag ccatataagt tttgcaatca ttggtggctt agtaagtgca
     1441 atttttgtat acgcgattgc tgtaagcgga aaagcaggcc ttacccctat aaaacttgcc
     1501 ttatcaggaa cttgtgttag tatggcttta agcagttttg taagtttttt aattttaccg
     1561 aataataacg tcttagacaa atttagattt tggcaaatag gtagccttgg agcagctaca
     1621 ttatcttcta tatctacact actacctttt ataattttag gtcacttgat agctatattt
     1681 atttcatcag atttaaacgc tttagctatg ggtgatgaaa tggctgttgg tcttggagtt
     1741 aatgttaata ggataagatc acttgcaata attgcaagtg tgcttttatg ttcaagtatt
     1801 actgcaattg gtggacctat tggcttcgta ggtcttatag ttcctcactt ttgtggctta
     1861 tttataagca aagatatacg cacaatgacc atttcttcat cttttatagg tgcagagctc
     1921 ttgcttatat gtgatataat cggccgtatg ttaggtaaac caggtgaaat tgaagtaggg
     1981 ataattactg caataatcgg gggtccagta cttatttatg taactatgaa aaatagaggg
     2041 gttaataact aatgcaaaat ttaattatag gtattcaaaa aagaaaaaat agaataacac
     2101 tattttcctc actattttta ttaataataa tcagtctatc atttttcgtt ttacttatcg
     2161 gagatgaaag ttattctttt tcaactttga ttaaagtctt aaatagtgaa actgttcctg
     2221 gagctagttt ttcgattatg gaaattagat taccaaaatt attagcagga attatagctg
     2281 gctggtcttt tggattggca ggatttatct ttcaaactat gttaagaaat cctcttgcaa
     2341 gtcctgatat aatcggtgtc acaagttctt catctattgc agcggtcttt tgcatattgg
     2401 tattaaaaac aaatagttta actactggaa ttatttcaat aacttgtgga ctaacatcat
     2461 ctttaatatt atttttacta gctaaaaaag atggtttttc agcagcaaga ctgataatat
     2521 taggcattgg ttttcaagct gtcacaagag caggcacctc atttttattg ttgaaagtag
     2581 caagatatga attacaagaa gttatgagat ggctcagtgg ctctttatct tttacaaagt
     2641 tagatgacat acctcttgtt ctaatagtaa gtattattgc tactatatta gttttatttt
     2701 ttaataaaag actagaaatt attgaacttg gtgaagaaat agcaatcgga cttggagcaa
     2761 atcccgagct ttcaaggctt gttttaattt tttgcgctgt atctttaact gctttttcta
     2821 cttcaattac aggaccaata gcttgtatat cttttttagc tggtcccata gccttaaata
     2881 ttggcaagaa aagaagccca atattagctg gattggttgg aattttacta gttttgttat
     2941 cagacatatt ctctcaaaat attttaccag ctagatatcc agtaggtgtt gtaactggct
     3001 tgttaggttc accatactta atatatttac taataaaaat gaacaggagg aatatataat
     3061 gaaaggtctg tggtcaaata atcttacctg cggttatgat gaaaaaataa tcttggaaaa
     3121 tataaatata aaaatacctg aagaaaaaat atcagttatt attgggtcaa atggttgtgg
     3181 gaaatcaaca ctcattaaaa ccttgtctcg acttataaag ccattagagg gagaagtatt
     3241 gcttgataat aaatcaatta attcttataa agaaaaagat ttagcaaaac acatagctat
     3301 attacctcaa tctccaataa tccctgaatc aataacagta gctgatcttg taagccgtgg
     3361 tcgtttcccc tacagaaagc cttttaagag tcttggaaaa gatgaccttg aaataataaa
     3421 cagatcaatg gttaaggcca atgttgaaga tctagcaaat aacctagttg aagaactttc
     3481 tgggggtcaa aggcaaagag tatggatagc tctagcccta gcccaagata caagtatcct
     3541 acttttagat gagccaacta cttacttgga tatctcatat caaatagaac tattagacct
     3601 cttgactgat ctaaaccaaa aatataagac aaccatttgc atgattttgc acgatataaa
     3661 tctaacagca agatacgctg attacctatt tgcaattaaa gaaggtaaac ttgttgcaga
     3721 gggaaagcct gaagatatac taaatgataa actagttaaa gatatcttta atcttgaagc
     3781 aaaaattata cgtgacccta tttccaattc gcctctaatg attcctattg gcaagcacca
     3841 tgttagctct taataattga atattggaat tcatttaaaa gtcgcaaatt ttgaactgac
     3901 cctcaaaagt taggccaaaa aactaactaa aggaggtcag ttttttaatg gcaaatacag
     3961 cacagaattt aagataaaat tagtaaaaga atatcatgaa tgaaaaatag gatatagaga
     4021 ataacagcaa tattaaaaag atcaggactg ataataaaca aaaagaaagt acaacgacta
     4081 gttcaaaagc taaaacttca agtaaaaagt tattcaagaa aatctagaaa atactcatcc
     4141 tacaaaggac aggtaggaaa aatatcagac aacaaaataa aaagaaatat ttattaccga
     4201 aaaaaagggg aaatcgagtc aagtaccaac aggctcatct attccaaaaa gatatttact
     4261 cgatggaaaa actcctagaa ttagtgctac aaatattgac aatggtatct taggttacta
     4321 cgaagatata gatgataaaa attatagagt ttttgaaaat tttatatctg tttcattttt
     4381 a
//
LOCUS       DAVLHM010000083         4011 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLHM010000083 DAVLHM010000000
VERSION     DAVLHM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.083"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(146..1207)
                     /gene="dinB"
                     /locus_tag="VXE45_002047"
     CDS             complement(146..1207)
                     /gene="dinB"
                     /locus_tag="VXE45_002047"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0790013.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            1556..3880
                     /gene="pflB"
                     /locus_tag="VXE45_002048"
     CDS             1556..3880
                     /gene="pflB"
                     /locus_tag="VXE45_002048"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0790014.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         1207 a          846 c          777 g         1181 t
ORIGIN      
        1 aaaaaccttg aaggggcaac tcttcaaggt tttatactct tagaaaatct cttcaaaccg
       61 cgtcagcttt atctgcaacc tcaaaacagt gttttgagca gcctgcggct agcttcctag
      121 tttgctcttt gattttcatt gagctttaaa atccagtcag ggtaatcccc aataggcgga
      181 cacctctttc tttctcgctt aattcttcat agagttgcag ggctatttgg cttatctgac
      241 tagcatcttg tgttttttga gcaagacttt ttcgtttggt aagagttgaa aagtcctcgt
      301 agcggatttt caaaatgaca atttttccag ctttttcttg ttgatgtaga ttgagagcga
      361 ctttttctga tagaagagtc agctcttttt tgatatcttc ctcagcaagg agaatcttcc
      421 cgtaggtttt ctccttgccg attgatttac ggatgcgatt ggatttgact ggagagttgt
      481 gaatgccacg agcctttcga tacagatcat agcctagtct accaaaacgg tctattaggg
      541 ttacctcagg aacttcaagt aaatcagcac cagtaaaaac gcccatttga tgaagacgtt
      601 ctactgtctt ttttcctact ccatgaaatt tggaaatatc catttgtttg agaaaatcct
      661 cagcctgttc aggtagaatc actgtcaaac catgtggttt ttgataatca ctcgccattt
      721 tagctaagaa tttgttgtaa gaaacgcctg cggaagcagt tagatggagt tcttgccaga
      781 tatctttttg aatgaggcga gcaattttga ccgctgactt gataccgagt ttattttctg
      841 tcacatccaa ataggcttcg tcaatgctca tgggttcaat caaatctgta tagcgcttaa
      901 aaatagctcg aatctggagt cccacagact tgtatttctc ataattccct gagataaaga
      961 cagcctgggg acaacgttca taagcttcct tggaactcat ggcagaatgg acaccaaaag
     1021 ctcttgcctc ataactacag gtagaaacga ctccccgtcc acctgtttgc cgagggtcgc
     1081 ttccaataat gacaggtttt cctctgagtt taggattatc cctgatttcc actgcagcaa
     1141 aaaaggcatc catgtcaata tggatgattt ttcttgacaa atcatttaac aaaggaaaaa
     1201 tcaacatgcc tagcaccttt ttatactctt cgaaaatctc ttcaaaccac gtcagctcta
     1261 tctgcaacct caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgcttttcg
     1321 atttccattg agtgttactg cttattttct tttattatac ccttttttct gaaaaaaaga
     1381 aaaaaggact ttattttttc aaaaatataa tacagtttga aataaaatat agactgtttt
     1441 agaaaagaaa gtgtaaaaat agggaatttt cacttgttga aatcggttac tatatggtat
     1501 acttgtctta tgaatgtaac agatgactgt tactagaaaa aaagaggaca ttaatatggt
     1561 tgttaagaca gttgttgaag cacaagatat ttttgacaaa gcttgggaag gcttcaaagg
     1621 cgtagattgg aaagaaaaag caagtgtatc acgatttgta caagctaact acacacctta
     1681 tgatggagac gaaagcttcc ttgcaggacc aacagagcgt tcacttcaca tcaagaaaat
     1741 tgtagaagaa actaaagcac actacgaaga aactcgtttc ccaatggaca ctcgtccaac
     1801 atctatcgct gatatccctg ctggatttat cgacaaagaa aatgaagtta tctttggtat
     1861 ccaaaatgat gaactcttca aattgaactt catgccaaaa ggtggtatcc gtatggctga
     1921 aactacttta aaagaaaatg gatacgaacc agacccagct gttcacgaaa tcttcactaa
     1981 atatgtaaca acagttaacg acggtatttt ccgtgcctac acttcaaata ttcgtcgcgc
     2041 tcgtcatgca cacactgtaa ctggtcttcc agatgcatac tcacgcggac gtatcatcgg
     2101 tgtttacgca cgtcttgctc tttacggtgc agactacttg atgcaagaaa aagtaaacga
     2161 ctggaatgca atcaaagaaa tcgatgaaga aacaatccgt cttcgtgaag aagtaaacct
     2221 tcaataccaa gcattgcaac aagttgttcg cctgggtgac ctttacgggg ttgatgttcg
     2281 caaaccagcg atgaacgtga aagaagcaat ccaatgggtt aacattgctt tcatggctgt
     2341 ctgccgtgtg attaacggtg ctgctacatc tctaggtcgt gtaccaatcg tattggacat
     2401 ctttgcagaa cgtgaccttg ctcgtggtac atttactgaa tcagaaatcc aagaattcgt
     2461 tgatgatttc gttatgaaac ttcgtacagt taaatttgct cgtacaaaag cttatgacca
     2521 attgtactca ggtgacccaa cctttatcac aacttctatg gctggtatgg gtaacgacgg
     2581 tcgtcaccgt gttactaaga tggactaccg tttcttgaac acacttgaca acatcggtaa
     2641 ctcaccagaa ccaaacttga cagttctttg gactgacaaa ttgccataca acttccgtcg
     2701 ctactgtatg cacatgagcc acaaacactc ttctatccaa tacgaaggtg taacaacaat
     2761 ggctaaagac ggatatggtg aaatgagctg tatctcatgc tgtgtgtctc cacttgatcc
     2821 agaaaatgaa gaacaacgcc acaacatcca gtacttcggt gctcgtgtaa acgttcttaa
     2881 agcccttctt actggtttga atggtggtta cgacgatgtt cacaaagact acaaagtatt
     2941 tgatatcgaa ccaatccgtg acgaagttct tgaattcgaa tcagttaaag cgaactttga
     3001 aaaatctctt gactggttga ctgacactta cgtagatgcc ttgaacatca tccactacat
     3061 gactgataga tacaactacg aagctgttca aatggccttc ttgccaacta aacaacgtgc
     3121 caacatggga ttcggtatct gtggatttgc taacactgtt gatacattgt cagctatcaa
     3181 atacgctaca gttaaaccaa tccgtgacga agatggctac atctacgatt acgaaacaat
     3241 cggtgactac ccacgctggg gtgaagatga cccacgttca aacgaattgg cagaatggtt
     3301 gatcgaagct tacacaactc gtctacgtag ccacaaacta tacaaagacg cagaagctac
     3361 agtatcactt ttgacaatca catctaacgt tgcttactct aaacaaactg gtaactcacc
     3421 agttcacaaa ggtgtatacc tcaacgaaga tggttctgtg aacttgtcta aacttgaatt
     3481 cttctcacca ggtgctaacc catctaacaa agctaaaggt ggttggttgc aaaacttgaa
     3541 ctcactttct agccttgact ttagttatgc agctgacggt atctcattga ctacacaagt
     3601 atcacctcgc gctcttggta agactcgtga tgaacaagtt gataacttgg taacaatcct
     3661 tgatggttac ttcgaaaacg gtggacaaca cgttaacttg aacgttatgg acttgaacga
     3721 tgtttacgaa aaaatcatgt caggcgaaga cgttatcgta cgtatctctg gatactgtgt
     3781 aaacactaaa tacctcactc cagaacaaaa aactgaattg acacaacgtg tcttccacga
     3841 agttctttca atggatgacg ccttggatgc attgagctaa tcaagttcgg ctctttgtca
     3901 actgcagtgg gttgaagtcg gctaagctcg agaaaggaca aaattcgtcc tttctttttt
     3961 gatgttcaga gcgataaaaa tccttttttt gaagttttca aagttccgaa a
//
LOCUS       DAVLHM010000084         3830 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLHM010000084 DAVLHM010000000
VERSION     DAVLHM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.084"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(81..713)
                     /locus_tag="VXE45_002049"
     CDS             complement(81..713)
                     /locus_tag="VXE45_002049"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0790015.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            complement(747..1448)
                     /gene="pyrF"
                     /locus_tag="VXE45_002050"
     CDS             complement(747..1448)
                     /gene="pyrF"
                     /locus_tag="VXE45_002050"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0790016.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            1769..1861
                     /locus_tag="VXE45_002051"
                     /pseudo
     CDS             1769..1861
                     /locus_tag="VXE45_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2183..2896)
                     /locus_tag="VXE45_002052"
     CDS             complement(2183..2896)
                     /locus_tag="VXE45_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0790017.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(2889..3722)
                     /locus_tag="VXE45_002053"
     CDS             complement(2889..3722)
                     /locus_tag="VXE45_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0790018.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
BASE COUNT         1197 a          777 c          647 g         1209 t
ORIGIN      
        1 attttattta aaatattgtc atattttaaa taaaatggta aaagaggctc ggtagcctcg
       61 tctctcttta tcttactgac ctaaccttct tgccaatttt cttggtcgtc tttaaagcgt
      121 tttagaagat caaggccctc tggcgtgatg taaccttctt cttgggctag atggataagc
      181 tcgctatagt ttgaaagcgt cacaagttta acaccagcat ctgcaaagtt cttatctgct
      241 tttggcaatt ggtagctgaa aatcgctaca actccaagca catctgctcc ttctcgcttg
      301 gctgctgcta cagcttcaag aactgaacca cccgttgaaa taaggtcttc aaccactacc
      361 attttttgac cttgagctac gcgaccttcg atttgattac cagctccatg gtcttttggt
      421 ttgctacgga tgtaggcaaa aggcaagtcc atcttatcag caataatggc tccgtgtgga
      481 atccctgctg ttgcagttcc tgcaatcact tctacttcag gaaaggcttc tttgatagct
      541 tccacaaaac cattttcaat tagggtacga gtttctggat aggctagtgt cacacgatta
      601 tcagtgtaaa tcggtgactt gataccagat gcccaagtga agggttcctc tggtttgagg
      661 taaacggctt ggattttcaa gaggtggcta gcgatatctt tagcaagtgt catggtattc
      721 tccttttatt tttctaatct agttctttaa ttccagtcct gtgtccattc atccttgatg
      781 gcatgataag ctgcaacagg atcctcagct tgggtaatgg gacgtcccac tacgatatag
      841 tcactgccga tttgataggc atcagcaggt gtcatgactc gtttttgatc tccaactgca
      901 acaccagctg gacgaatccc tggtgtcaga cagataaaat ctggattggt agcctgcttg
      961 atgacttgta cttcctgagc cgagcaaaca acaccatcca agccagcttc agctgtcttc
     1021 ttggcatagt gaatcacaga ctcttgcaga ctggtttgga tattttgaaa ctcctgcatc
     1081 tgagcttctg acgttgatgt gagctgagtt acagcgatca atttggcttg acttccaaga
     1141 ccttcacgcg cagccttcat catctctaca ccaccagccg catgaacatt ggtcatatcc
     1201 acaccaagct gagataggat cttcattgct gacttgactg tattaggaat gtcatgaagt
     1261 ttgagatcca aaaagacact atgacccaaa ccttttaagt aggacacaat ctcaggcccc
     1321 gctgcgtaat aaagctccat ccctaccttg agataaaggc tttcttctgc tgggaaaaga
     1381 gctaaaaatt ccttgaccgc ctcaaaacta ggaaaatcaa gagcaatgat tggacgatgt
     1441 tctcgcatag gtttctcctt ttacctttac tagtgagaga gtctggccaa cagaagccac
     1501 gaaaaaagga acctgccaac agcaaggttc cacgaaaaat gggtagtctc caccctttca
     1561 ccgtctaacc ttagctgcct ctctggactg ctttaaaggt tttttactat tctattattt
     1621 ctactagcac ttgtcaagta aaaacatggt cacgtatgtg ttgactgcta ttgaacacct
     1681 cacaagactc tttccaaaag aatagttaaa gactttcact taggacagag aaaaagagtt
     1741 tgcttgttac cctttaattg aacaaatggg aattctgttt tattttgcgg atgcctattc
     1801 atcttggcaa aggggaagta atgagaatgc gaatggactt cttcgtgagt attttcttaa
     1861 accgatttgg caacaattac cgaaaaaatc cttaatggtg ctttgctagc ttattaatca
     1921 ccgtccccaa aaatacttgg attacaagac aggttttgaa gcacttatag aggagattta
     1981 aaaatgttgc attttttatt gcaatttatc agttatctta tcacccaaaa cttctgcaat
     2041 tagtatgagc actattgtta tttttctttt ttcgtacact caaatcaaaa tatagcaata
     2101 agactattct gtagaattgc tgtcaaaaag atcagttcat ttttccttcc cacttgtgtt
     2161 tataatcatt aaaataactc aattaagaaa ttttcttttt cctaatagtt atcgtaatta
     2221 aagttaatag aagaacaatc caaataagta gtgttagatt aggaattaga gtttcattcc
     2281 atgaaaatcc ctcccatttt gtgaaaaact tagtaaacag tcccataaaa ctataatctg
     2341 ttatcttcgc aactgtctta tccaaaccag atagcatcgg taagaaagca actaaaatca
     2401 tagcaggaag actgataacc tgagctacta cttggctctt cgcggttaaa cctatcaata
     2461 aatagaataa aatgatggat aaagaggtta gaagaacgat tgtaatataa ttaaaagtat
     2521 gtacaattgt aactcctaaa ataagaggag tagttcccat aatcacaaaa gttagcaaaa
     2581 aaggaagaaa catcgttgat aaaatgtatt cggatccttt aacaccactc aacagaagag
     2641 tttgtaaatt gtacttttct ttttcttcag acaagataat agttatagga cttccaacag
     2701 ccaaagccaa agaaaaaggt aaacacatca tcaaaagaac taatgcctgt tgatcgttga
     2761 ccttcccctg tgtttccata agatatttat aaaaatatgt gaaagcaaaa ggcactaaaa
     2821 cttgcaataa aatactctta ttggaaagga taatttgaca acgcaaccat accaaagcca
     2881 gaaaccgttt aagcatttag ctttcctcct gttaatgtga taaaaatatc ttctaaagta
     2941 ggctcacatg aatgaattga aaaaatattt tccagatcag cctgagatac ctgttctagt
     3001 gatgtaaaat caaaagttat ctgattccca ttataatctg taaccttaat ctttttatct
     3061 ttattatatc tttgaatgag ttcagaagga gctccttgct caactaattt ccctttattt
     3121 aataaggcaa cataatcaca taaaagagtt gcttcattca tatcatgagt cgttagaaaa
     3181 atcgttgtcc ctgctgtttt caattctaaa attaactcat gaattgttcg agaagttgtg
     3241 ggatctagac ctgaggtcgg ttcatccaga aagagtacag cgggtttgtt gataagagct
     3301 cgtgctaaaa gcattcgttg cctcattcca gtggataatt ttcctgctac catcttgcaa
     3361 ctatcatata atcctactcg ctttaacaaa ttatcaacac gtaatttact aatattataa
     3421 aatttactat aaaaaagaag attgttatac agagacattt tctcataaaa tccacttgta
     3481 tcgctaacca atccaattct ctttaattca ccgcttgtta aattttgaga tttttgtccc
     3541 aaaataatag attgtccttt atcggcaagg agctgcccag tcagaatatt aatcgttgtg
     3601 gtctttccag aaccagatgg tcctaaaaat ccaaaaatct gaccttcttt aacagtgaaa
     3661 cttatatcat ttaaagctat tttatcacca aaactttttg ataaatggct aacttcaatc
     3721 atactcattg cccctccttt atattctaca tttttactta acatctattt acttagcttt
     3781 atcaaataaa cgtcttaaaa aaaacaataa cattaagcat ataaccgtta
//
LOCUS       DAVLHM010000085         3619 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLHM010000085 DAVLHM010000000
VERSION     DAVLHM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.085"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..177
                     /locus_tag="VXE45_002054"
     CDS             <1..177
                     /locus_tag="VXE45_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790019.1"
                     /translation="AEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDS
                     LLALLKESQPTPIQ"
     gene            387..3506
                     /gene="phtE"
                     /locus_tag="VXE45_002055"
     CDS             387..3506
                     /gene="phtE"
                     /locus_tag="VXE45_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0790020.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLKEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1350 a          590 c          697 g          982 t
ORIGIN      
        1 gcggaggcct tgctagaaaa agtaacagat tctagtatta gacaaaatgc tgtggagaca
       61 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      121 gaagtagata gtctcttggc tttgttaaaa gaaagtcaac cgactcctat acagtagtaa
      181 aatgaatgga gcatatttta tggagaagta acctttcgtg ttacttctct tttttagaaa
      241 aacgtaacag aaacttgaca aaagtaattt taaatagtaa actatttact ggttaattaa
      301 atggttaaat aaccggttta gaaaactatt taataaagta aaagaagttg agaaaaaact
      361 tcatcattta ttgaaatgag ggatttatga aattcagtaa aaaatatata gcagctggat
      421 cagctgttat cgtatccttg agtctatgtg cctatgcact aaaccagcat cgttcgcagg
      481 aaaataagga caataatcgt gtctcttatg tagatggcag ccagtcaagt cagaaaagtg
      541 aaaacttgac accagaccag attagccaga aagaaggaat tcaggccgag caaattgtaa
      601 tcaaaattac agatcagggc tatgtaacgt cacacggtga ccactatcat tactataatg
      661 ggaaagttcc ttatgatgcc ctctttagtg aagaactctt gatgaaggat ccaaactatc
      721 aacttaaaga cgctgatatt gtcaatgaag tcaagggtgg ttatatcatc aaggtcgatg
      781 gaaaatatta tgtctacctg aaagatgcag ctcatgctga taatgttcga actaaagatg
      841 aaatcaatcg tcaaaaacaa gaacatgtca aagataatga gaaggttaac tctaatgttg
      901 ctgtagcaag gtctcaggga cgatatacga caaatgatgg ttatgtcttt aatccagctg
      961 atattatcga agatacgggt aatgcttata tcgttcctca tggaggtcac tatcactaca
     1021 ttcccaaaag cgatttatct gctagtgaat tagcagcagc taaagcacat ctggctggaa
     1081 aaaatatgca accgagtcag ttaagctatt cttcaacagc tagtgacaat aacacgcaat
     1141 ctgtagcaaa aggatcaact agcaagccag caaataaatc tgaaaatctc cagagtcttt
     1201 tgaaggaact ctatgattca cctagcgccc aacgttacag tgaatcagat ggcctggtct
     1261 ttgaccctgc taagattatc agtcgtacac caaatggagt tgcgattccg catggcgacc
     1321 attaccactt tattccttac agcaagcttt ctgccttaga agaaaagatt gccagaatgg
     1381 tgcctatcag tggaactggt tctacagttt ctacaaatgc aaaacctaat gaagtagtgt
     1441 ctagtctagg cagtctttca agcaatcctt cttctttaac gacaagtaag gagctctctt
     1501 cagcatctga tggttatatt tttaatccaa aagatatcgt tgaagaaacg gctacagctt
     1561 atattgtaag acatggtgat catttccatt acattccaaa atcaaatcaa attgggcaac
     1621 cgactcttcc aaacaatagt ctagcaacac cttctccatc tcttccaatc aatccaggaa
     1681 cttcacatga gaaacatgaa gaagatggat acggatttga tgctaatcgt attatcgctg
     1741 aagatgaatc aggttttgtc atgagtcacg gagaccacaa tcattatttc ttcaagaagg
     1801 acttgacaga agagcaaatt aaggctgcgc aaaaacattt aaaggaagtt aaaactagtc
     1861 ataatggatt agattctttg tcatctcatg aacaggatta tccaagtaat gccaaagaaa
     1921 tgaaagattt agataaaaaa atcgaagaaa aaattgctgg cattatgaaa caatatggtg
     1981 tcaaacgtga aagtattgtc gtgaataaag aaaaaaatgc gattatttat ccgcatggag
     2041 atcaccatca tgcagatccg attgatgaac ataaaccggt tggaattggt cattctcaca
     2101 gtaactatga actgtttaaa cccgaagaag gagttgctaa aaaagaaggg aataaagttt
     2161 atactggaga agaattaacg aatgttgtta atttgttaaa aaatagtacg tttaataatc
     2221 aaaactttac tctagccaat ggtcaaaaac gcgtttcttt tagttttccg cctgaattgg
     2281 agaaaaaatt aggtatcaat atgctagtaa aattaataac accagatgga aaagtattgg
     2341 agaaagtatc tggtaaagta tttggagaag gagtagggaa tattgcaaac tttgaattag
     2401 atcaacctta tttaccagga caaacattta agtatactat cgcttcaaaa gattatccag
     2461 aagtaagtta tgatggtaca tttacagttc caacctcttt agcttacaaa atggccagtc
     2521 aaacgatttt ctatcctttc catgcagggg atacttattt aagagtgaac cctcaatttg
     2581 cagtgcctaa aggaactgat gctttagtca gagtgtttga tgaatttcat ggaaatgctt
     2641 atttagaaaa taactataaa gttggtgaaa tcaaattacc gattccgaaa ttaaaccaag
     2701 gaacaaccag aacggccgga aataaaattc ctgtaacctt catggcaaat gcttatttgg
     2761 acaatcaatc gacttatatt gtggaagtac ctatcttgga aaaagaaaat caaactgata
     2821 aaccaagtat tctaccacaa tttaaaagga ataaagcaca agaaaactca aaacttgatg
     2881 aaaaggtaga agaaccaaag actagtgaga aggtagaaaa agaaaaactt tctgaaactg
     2941 ggaatagtac tagtaattca acgttagaag aagttcctac agtggatcct gtacaagaaa
     3001 aagtagcaaa atttgctgaa agttatggga tgaagctaga aaatgtcttg tttaatatgg
     3061 acggaacaat tgaattatat ttaccatcgg gagaagtcat taaaaagaat atggcagatt
     3121 ttacaggaga agcacctcaa ggaaatggtg aaaataaacc atctgaaaat ggaaaagtat
     3181 ctactggaac agttgagaac caaccaacag aaaataaacc agcagattct ttaccagagg
     3241 caccaaacga aaaacctgta aaaccagaaa actcaacgga taatggaatg ttgaatccag
     3301 aagggaatgt ggggagtgac cctatgttag atccagcatt agaggaagct ccagcagtag
     3361 atcctgtaca agaaaaatta gaaaaattta cagctagtta cggattaggc ttagatagtg
     3421 ttatattcaa tatggatgga acgattgaat taagattgcc aagtggagaa gtgataaaaa
     3481 agaatttatc tgatctcata gcgtaaggaa tagcagtaga aaaagtctga atcaaaaatg
     3541 aagttctctc aaaagttaga aataaaactc tgactttggg agaatttcat tttattatta
     3601 atatataaaa tttcttgac
//
LOCUS       DAVLHM010000086         3607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLHM010000086 DAVLHM010000000
VERSION     DAVLHM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.086"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            58..1068
                     /locus_tag="VXE45_002056"
     CDS             58..1068
                     /locus_tag="VXE45_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEV0790021.1"
                     /translation="MVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFM
                     YYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLA
                     CLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLG
                     DTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIH
                     SLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELES
                     LLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLL
                     EI"
     gene            1418..2122
                     /locus_tag="VXE45_002057"
     CDS             1418..2122
                     /locus_tag="VXE45_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEV0790022.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            2103..3032
                     /locus_tag="VXE45_002058"
     CDS             2103..3032
                     /locus_tag="VXE45_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEV0790023.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            3029..>3607
                     /locus_tag="VXE45_002059"
     CDS             3029..>3607
                     /locus_tag="VXE45_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0790024.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRM"
BASE COUNT         1285 a          438 c          614 g         1270 t
ORIGIN      
        1 ccaaatgaaa gtttagttac tattctgcat aatgaagtag aaaatattgc agactctttg
       61 gttattaata atatttatga cgaatatcca atttggagta tacctgttaa ttttaaaggt
      121 tctaaatggt gtcttgaaca aacgggtaat gatatgtata ggggtagagc tggaatatta
      181 ctgtttatgt actatgtaaa attattgaaa gataaatcat catatactca actgtacaat
      241 aaaatgttat ctgcaattcc gccatctgtt tctttatcta agaccacatt tggtttaact
      301 ggggatatag gatatttcat tgttctatcc attatagagg attacgatac aaatactctc
      361 gcatgcttaa attatataaa gagtgtttta actgagcttg aaaagactga ttttgcaagt
      421 gtttcaaaca agtctgacta tattaatggt cttctacctt taattaatac actggtaaga
      481 tattatagga gaggaataga gaaggaacgt gttctaaggc tagtattaag tttaggtgat
      541 acgctatata atgatgtaag cgagagagat aatagtaatt ttggatatag ttttggccat
      601 ggactatcag gtgtaatttt tacattaaaa aatatttata aagtgacaag acttaaaaaa
      661 tataaagaat taattttaca actagttcct agggagaaaa tcaaaattca ttctttgaag
      721 tggtgtagtg gagaatttgg gacattagtt aatcatcccc aaagtgttcc agagggaatt
      781 gtagctagtt tagataatga tacattttgc catggaagta tggccataat aaatttttac
      841 atcgactaca tgaaagaaat ggatactagt atggaattgg agtctttatt gtgtagtgtt
      901 gtaatgaata aatcaaaaga aggagagtat cgtatcgtcc aaacaagcaa tttcccagat
      961 ttttctttgt atacaggtgt gactggtatt gcttatactt ttttaaggta tatcgcactg
     1021 aatcagaatg acaaaaagat agttatcccc tcattacttg aaatctagct taatttatag
     1081 ttttgtttct aaaatagagg tgtccactca ttaagcaata taaaaatacc aagattgact
     1141 agtttaatat gtaattctat aaaatatttt taatagtgta gcttttcatt gagataataa
     1201 tataataaag aaaagttcta ttctaattgc taaacggctt gaggtatatg ctactgttat
     1261 agaaatgatt ttaaactaaa atcaaaatta ctccaaaaat agtattgatt ttggtttaat
     1321 acaaaacata tgtaataatg tgagtcaaca aaagtctgtt tttgtaccat actatcttga
     1381 aaaatctact aaattcaaat tgagaggatg aattaaaatg aataaaatat ttatatatgc
     1441 aggagtgcga aatcataact ctaagacttt agagtatact aagagacttt caagtatcat
     1501 ttctagtaga aataatgttg atatatcttt caggacacct ttcaattcag agctagaaat
     1561 atctaattct gattcagaag agttgtttaa gaaaggaatt gataggcaaa gtaatgctga
     1621 tgatggaggt gttataaaaa aagagttatt agagtctgat attataatta tctcttctcc
     1681 tgtatattta caaaacgtat ctgtggacac aaaaaacttt attgaaagga ttggggggtg
     1741 gagccatctt tttcgattag ctggaaagtt tgttgtaaca ttagatgttg ctgagagtaa
     1801 cggctctgat aatgtgtcag aatatcttag agatatattt tcatatatgg gaggacagat
     1861 attacaccaa gtttcaatta ccaattcact caaagatatt gcagaggctc agttgatgga
     1921 ggcaacttat aaaattgaag atgtacttga agggaaaatt aagtacaaaa caacggatta
     1981 tcaagaaaga gcttaccaga cattaaaatt aattttagaa aattatgatt ccgaacattt
     2041 tgagaagatg tattgggaga aaaaacgcct ttttgaagct aatagtttag aggaatggta
     2101 ttatgttgaa aatattaaat aactctgtca tatatttatg tttgattccg ttattgttcc
     2161 tattattgat aatttttcca aatgattcat taatctatta ttttcgattg attttaattt
     2221 cgttaatatc aattacatta catgaactag gtcatttttt agtgggaaga tgtttatctt
     2281 ataaactaga gatgcttgct actccctttt tcttctattt cagaaaaaaa atatatttca
     2341 aatttccagt gttattagca ttcggttatt gtcaaatgag taatagaaac attactaatg
     2401 aaaaaaatag tgataggaat ttggtgttct acttctttgg gggaggtgga gctaacctaa
     2461 ttgtcgcaat attagcactt ttgggatttg tgccgtacgc atcagaattt tttattttga
     2521 atataattct ttttctagtt acggtatgtt taccaattga tggaacagat ggcaatgcta
     2581 ttagagagat agttttgtat tcaaaagatt caaaaacata tcagagattc tttgcgaaca
     2641 gtctctataa taatccttat ataacaatcg acgattttgc aaaattaacc tctaaagaaa
     2701 aatctttttt ttcaaaattt gaaaaatgtt tgataaacct ttactttgaa gtgaaaggtg
     2761 aagggtcagc atttacaatt gctaatcatg aagtttttga ttcaaatatt caggaaaata
     2821 ttatccatga gtactataaa ttactacata aatcttctga ttggattatt ccacagaact
     2881 tatctttaga agaagttgtt tttaccttgt caaactatat ttactcgaaa aataataaat
     2941 atttagaaaa gattaagtat ctaaagaaat tagtagattt tagacaagaa gaaattatcg
     3001 actttatttt gaacaaggag gaagtattgt gaaaattcca atgatatatc aaatggaaaa
     3061 ttcagaatgt ggattagcat gctgtgccat gatattgaac tattttaaat atgagatttc
     3121 tttaaatgaa ctacgtgaaa tctacccatc atccagatct ggatattctc tcctatctat
     3181 aagtaaagtt ttaggagatt ttaatataag ttctcatgct tttaaagctt cggtaagaga
     3241 tttaaaaccg ctcagtttcc cactcatttg cttctgggag agttctcatt ttattattct
     3301 tgaaaaaatt agtaaaaaca agttttatat tttagatcct gcaaaaggca ggcagagaat
     3361 gtcaataagt gaatttgaaa ggcattattc aaatatcatt ttaacattta aaaagttaga
     3421 tagctttatg tctcgtaaag ataataagaa gtcgcctgtt ttaaagtatt tttttaagta
     3481 taggaataag ctagggattt tattttttgt aacagcatta ttgtatgtaa tacaatcatt
     3541 agtacctata gctaatagat acataattga cacgaatttc aaggacgatt cgtattcgtc
     3601 tagaatg
//
LOCUS       DAVLHM010000087         3541 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLHM010000087 DAVLHM010000000
VERSION     DAVLHM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.087"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(237..848)
                     /gene="rpsD"
                     /locus_tag="VXE45_002060"
     CDS             complement(237..848)
                     /gene="rpsD"
                     /locus_tag="VXE45_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0790025.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1043..2095)
                     /locus_tag="VXE45_002061"
     CDS             complement(1043..2095)
                     /locus_tag="VXE45_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0790026.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2092..2790)
                     /locus_tag="VXE45_002062"
     CDS             complement(2092..2790)
                     /locus_tag="VXE45_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0790027.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            complement(2957..>3541)
                     /locus_tag="VXE45_002063"
     CDS             complement(2957..>3541)
                     /locus_tag="VXE45_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV0790028.1"
                     /translation="PWSDNGDAKNPALSPLGENVKTKGQYFYQLALDGNVAGKEKQAL
                     IDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSN
                     SGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPN
                     TGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          977 a          791 c          684 g         1089 t
ORIGIN      
        1 ttcgctcaca ataagagaga acttttttac gaaaatctat tgaatatgcc ataaaagatt
       61 ataccacatt gtgtactatt tttggttcat tttactatat cactttggac tatatcggtc
      121 tagttatgtc tcaacgatta tagctggata ctaagagaaa tcaaaaaagc actaagggag
      181 aacgtcccaa agtgcttaat atcaaggcct caaagcctgt cttattcaat aaaatattac
      241 aacatcttgt tgtagaattc aacgacaagt gcttcgttga tttctgggtt gatttcgtcg
      301 cgttctggca agcgagtcaa tgaaccttcc aacttttcag cgtcgaatga tacgaatgct
      361 ggacgtccaa gagtagcttc tactgcttca aggattgctg gaactttcaa tgatttttca
      421 cgaactgaga tcacttgacc tggagttacg cggtatgatg ggatatcaac gcgtttcccg
      481 tcaacaagga tgtgaccgtg gtttacgaat tgacgagctt gacgacgagt agtcgcgaga
      541 ccaagacggt aaacaacatt atccaaacga cgttccaaaa gaagcataaa gttgaaacct
      601 aggattccac ctttgatttt tgtagcttgt acgaacaagt tacggaattg tttttcacct
      661 acaccgtaag tgaaacgaag tttttgtttt tcagccaatt gcaaaccata ttctgacaat
      721 ttagaacggt tgtttggtcc gtgttgtcct ggtacgtagt tacgacgtgc caattcttta
      781 cctgtacctg taagtgaaag gccaaggcga cgagcttgtt tccaagatgg tcctgtataa
      841 cgtgacatat gaatgtcctc ctgatataaa taatatttcg gtggaaatag tcacttagaa
      901 agccctgatt cgtgcagatg cccttcgcct aaacagccaa ggttacttgt cataagacac
      961 ctgttgacga gcttcatgct ttcctgctga tatttcacac aaaatccatt ttaccatgaa
     1021 tagctggatt tgtaaagggg ttttaggctt tattttcact accagagagg ttgagaacga
     1081 gggtaaaggt acttcctaga ccgtactggc tgctgactgt gatttcccca cccaattgat
     1141 gggccaattc acgcgcaatc gcaagtccta atccatgacc acctgtcttc atgttacgcg
     1201 aagtttcgac acgataaagg cgtttgaaaa tattttccaa atcctctggg gcaatgccct
     1261 gcccttcatc ggtcacactg attgaaagct ggtccttctc cagcttagcc accacttcca
     1321 gcttggttcc tggagcagaa tatttaaaag cgttatcgac cagattcacc aagatacgag
     1381 aaagcttagc ataatctccc tcaatccggg cagactctgg gattacctgc aagtggacat
     1441 ctcttctctc ctgctcaatc aaaaactgaa attcactcat gcactcaatt aagagcttgt
     1501 ccagaaaaat actgtcttta ctggtagttt ccacctgatt tctagctgtg tttagggtca
     1561 aaaaattcaa ctcctcaacc agtttattga gcctctccgt ctggcgtcca atggttgcta
     1621 gataatgagc ttgctccgac tccttgataa tcccatccaa aatcccttct accgtcgctt
     1681 ggatcgaagt gataggggtc ttaatatcat gcgacaactg ggcaatcatc aagccctttt
     1741 ctcgttcgct ttcttccaag gaatcaaagc ttacctgcaa atcatgggac atctcattaa
     1801 aagtttgccc taattgctga aattctacag gaccttgaac ctccaaattt gaaggaaaat
     1861 ccttggccgc tacccgcttg gcatgctcct tgagtttgcc caacgacgta aagactggca
     1921 ataggagaaa gagactaatc ccagcaccga caaggctggc aacgatggtc atcccaagca
     1981 aaaagtaaat ctcgcctttc gcaatcagca ttttttgaac agcccaaaaa acaaccaaaa
     2041 tggttaagag ggttgaaata atatatccaa ccaaaatata actttttagt ttcatatttg
     2101 tcctctcggt ttctctatct tatatcccaa cccccaaact gtcttaatag tgggagtttg
     2161 gtcactacta tattttgcca gctcctgtcg aagagcatgg atatgcacat tcaaggtatt
     2221 ggtgtcatcc acgtagtctt ctttccagat cttttcatag aggtctgtct tggagaaaac
     2281 tcgctctgga ttgctagcta aaatccacag caattcaaat gatttaacag ttaaatccag
     2341 catttcttct cctatttgaa cttcatgact actatgattc atttttagat tgccaaggga
     2401 aatcagctct gtttcgcccc cacgatgaag gcggcgcaaa atattgtgga cacgcaaaac
     2461 cagctcacgt gggctaaaag gcttagcaat aaaatcatct gctcccaagc tcaggccgta
     2521 aatcttgtcc tgttcactgg tcttagcagt aataaatagg aaaggctgct ctggtgataa
     2581 gtattgaacc tcactgatta aatcataacc atccatccga ggcatcatga catctgtgat
     2641 aatcaaatca atcggttttt tcttgaacag ctctagcgct tccagtccat catgggctac
     2701 caagacctga taacctgcct gaattaagta tctctgatga atatctgtga tttctacctc
     2761 gtcgtcaacg agtaaaattg tctttcccat ctgtctctcc tttgataaaa acagtgctat
     2821 actgctttaa gtataacact atttttattg ttttacgatg attttaatct gctattgaaa
     2881 gaaagtcctg attgctgatt gagttgttaa actaatctta gtcagcccac tatccatcat
     2941 ttatttcctt agctgattag ttttcttctt ttttgttttt caaacctaga ccaccgagta
     3001 aacctgcaag cgcaagccca aggaaaccaa tacttgccat tgatgtttga gtctcaccag
     3061 tatttggtag catagcttta tcctctgaca tcatcgtatc agacatcttg ttagcagaag
     3121 cagccatgtt ttcacctgcc atcgtgttgg tagaacttgt catggtgtca gcaggcatgc
     3181 tatctgtagt acctgtagca tgattgtgat tcatcggagt cacgccagaa ccagagttag
     3241 aaggtgataa tgaaccattt gctgtgtctg atgtttcttt aacatttatc ttaatagtga
     3301 cttttttagt tgctacgatg ttgtccaaat ctggtttacc gtctttgtta ccatagacat
     3361 tgactgtagc gctgtaagtt tgagtaccat ttgctcggaa ctggtcaatg agcgcttgtt
     3421 tttctttgcc agctacattt ccgtccaagg ctaattgata gaagtattga cctttggtct
     3481 tcacgttttc acctagtgga gatagagctg ggtttttagc gtcgccgtta tctgaccatg
     3541 g
//
LOCUS       DAVLHM010000088         3498 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLHM010000088 DAVLHM010000000
VERSION     DAVLHM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.088"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            19..579
                     /locus_tag="VXE45_002064"
                     /pseudo
     CDS             19..579
                     /locus_tag="VXE45_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            684..1032
                     /locus_tag="VXE45_002065"
                     /pseudo
     CDS             684..1032
                     /locus_tag="VXE45_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(1303..1524)
                     /locus_tag="VXE45_002066"
     CDS             complement(1303..1524)
                     /locus_tag="VXE45_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790029.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            1489..2118
                     /locus_tag="VXE45_002067"
     CDS             1489..2118
                     /locus_tag="VXE45_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790030.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            complement(2154..3377)
                     /gene="pepT"
                     /locus_tag="VXE45_002068"
     CDS             complement(2154..3377)
                     /gene="pepT"
                     /locus_tag="VXE45_002068"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0790031.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
BASE COUNT         1184 a          657 c          668 g          989 t
ORIGIN      
        1 tatagaaatg aggtaattat gaaatttaaa aagaaatata tagcagctgg atctgttgtt
       61 atcctttcct taagtctgtg tgtttatgct ctgaaccaac atagctaaca ggccaataca
      121 gataaaaatc gtgtttcata tgtaaacagt aataaagaca ctaagaagac tgaaaatttg
      181 actccagact aggttagtca aaaagaagga attcaagcaa aacaaattgt tattaagatt
      241 acagatcaag gttatgtaac ttctcatggc gatcattatc actactataa tggtaaagtt
      301 ccttttgatg cgctctttag tgaagagcca ttaatgaaag cccccaacta tcagccgaaa
      361 gatcaagata ttgtcagtta ggttaaggga ggatatatta ttaaggtaga tggaaagtat
      421 tatgtttacc ttaaagatca agctcatgca gaaaatgtac gaacaaaaga tgaaatcaat
      481 cgccaaaaac aagaacatgg taaagacgat aaaggagcta gtgcagaagt atctgtagca
      541 aaattacagg gacgttatac taccgatgat ggttatatat agtgagttga atttagaata
      601 gcacatcata gtttctaaat cattgttaga aattacttta aaatcccctt atcaatttgc
      661 tcatattcta tttcaatcta ctaatagtac cacatggtgg tcactatcat ttcattcctg
      721 agagtgactt gtcggcaggt gaattagcag ccacatatgt ctttaaccct aatgatattg
      781 tcagagatat aggtgatgct tatatagtaa gacatgggga acactatcac tatattccta
      841 agtcatctct taacaatccc ccatcacact ctaacacgga agaggtagga agttcttcta
      901 gttctgtatt aagtaatccg tcactacatg tccaccatga ggaagaagat ggtcatggtt
      961 tttgatgcca atcgaattat aagtgaagat tcagaaggtt ttgtgattcc tcatggcgac
     1021 cacaatcact acatcaaggt tcaaactaag ggatatgaag cggctttgaa aaacaagatt
     1081 ccatccctgc aatccaacta tcaacctgga acttttgatg agaaggcagt cttggcaaaa
     1141 gtagatcaac ttctagctga tagcagaagc atctacaaag acagattgag ttagctttag
     1201 gtcagtttac tgaaagtttg aaaaaaataa aagttagttg attgattact tctctaaatt
     1261 ttgggcacac taaaaagagg tcttgacacc taaactttaa aattaaagca tattgaatcc
     1321 gtgctgctgt gcgaagcgaa tagcgtcttg gacgaacatt gtcttatctg gatttcttat
     1381 ttctgtaagg ccttgtaatc ttggattata actctcctgt tttaggagta catggtagat
     1441 agcaaccaat aatctgcgac agatagcaag gaagaagtag aaagtctttt gaacaaggca
     1501 aatcaactct tggaacaaat ccatgaagaa ggaatcagac aatccttggc agaagaagta
     1561 gaaaatctaa aagctgccac aaacaaggct gatgcagact tggatgaagt aaacagtcag
     1621 gtaaaagatg ttttgactcg tatcgctagc gcccttcaac aagaaaagga aaatgctgag
     1681 caagattctc agacacttgt actctatcaa aaactctacg atattctcat gtcgcttcac
     1741 tcttatttag aaagtaataa tggatctgat gcggactttg ataaggtgga tgcattatta
     1801 gatcaacttt ctgctaatag taaagacaaa acagctttac ttgaatcgac aaaagctatt
     1861 ctagttttga atcatcaaat ccagtcaaaa gttagcgcaa gtgaagaaac aagtccagca
     1921 agaaatgctg aagcaaatag tgataacacc agtgctgaga accaaccaaa cgcaactgca
     1981 gaatctaaca ttgaaactgc tagcgacgaa aacaaaccaa gcaatacaag agattctaaa
     2041 cctgctgaat caacttcaga aaatgaaaca acagaatctt ctacaactac tggaaatcaa
     2101 gaaaaaccag tagaataaaa agaaaggcga agtagctgag ccacctcgtc tttttagcct
     2161 ttataagcta cgatgccaat gatggtatca actgcacgtt ccatagtctg aaggctaacg
     2221 tattcaaaac gtccgtgcat attttcgcca cctgcaaaga tattcggagt tgggattccc
     2281 ataaaggaaa tcttagagcc gtctgttcca ccccggattg gttcgataat aggcgtgata
     2341 cctagatctt ccataacggc tttagcaatg gtaattggag tcatatcttt ttcaatgact
     2401 tctttcatat tgtagtactg gtctgtcaag ttgagagtga cacggtcgct cccaagttct
     2461 tcattcatct tatcagcgat agattgcatg gatgctttac gcgcttcaaa ggcatctttt
     2521 tcaaaatcac gaatgatgta gcttgcacgc acctcctcaa cactacctgt cacatccatt
     2581 agatggtaaa aaccttggta accttcagtt aactcaggtc ggtcattttc tggaagttga
     2641 ttatgaaaat caattgctag ctgaagggca ttgaccatct gccctttggc agtaccaggg
     2701 tggacattac ggccttggaa atgcaattca gcaccagcgg ctgagaaagt ctcgtactga
     2761 agttcaccta gtggaccacc atcaacagtg taggcaaaat ccacatcaaa atcttctgca
     2821 tcaaatttat tggcaccaac accgatttct tcatctggac caaaaccaac acgaatctca
     2881 cagtgcttaa tttcaggatg agcagttaga tattcaatgg ctgtcataat ttcagcaatt
     2941 cctgacttgt catcagcacc tagcaaggtt gttccatctg ttgtgatgag tgtttgtcct
     3001 ggatattttt caagactctt gaagtcggct ggatcgagtt tgaaaccaga attccctagt
     3061 tcaatcacac caccatcgta gttttcaatt acctgtggat tgactccttc agcattaaaa
     3121 tcagcagtat ccatgtgcga tataaaacca atcttacgtg ttaaagacgg atcgttggct
     3181 ggcaaggttc caatagcaaa accattcggt agatagtaaa cattttgcag tccaacacgt
     3241 ttcatttcag gaattaggac atttgttgcg aagtcaacct gactctgtgt acttggagta
     3301 gtagtagagt gttcatcaga gcgcgtgttg accttaacgt aggttaagaa gcggtccaag
     3361 agatttggat aagtcataaa aaaactcctt ttttatcata aaatagaata caaaacttcg
     3421 gaaaaatatg atttgagaaa ttttatgaat tttgaaaaaa tataataatt caaattcaga
     3481 agactttcaa aagaaatt
//
LOCUS       DAVLHM010000089         3465 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLHM010000089 DAVLHM010000000
VERSION     DAVLHM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.089"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..492)
                     /locus_tag="VXE45_002069"
     CDS             complement(<1..492)
                     /locus_tag="VXE45_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790032.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDF"
     gene            complement(506..1219)
                     /locus_tag="VXE45_002070"
     CDS             complement(506..1219)
                     /locus_tag="VXE45_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0790033.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1679..2059)
                     /locus_tag="VXE45_002071"
     CDS             complement(1679..2059)
                     /locus_tag="VXE45_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV0790034.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2476..>3465)
                     /gene="phtD"
                     /locus_tag="VXE45_002072"
     CDS             complement(2476..>3465)
                     /gene="phtD"
                     /locus_tag="VXE45_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0790035.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPL
                     DRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYV
                     EHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEP
                     THPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAD
                     AEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESK"
BASE COUNT         1048 a          696 c          565 g         1156 t
ORIGIN      
        1 aaagtcgtca aaattagaaa acaatcgaaa atacaatgca ttctcttggt gtaaaatcgc
       61 tctttttaaa ggataatact ctttaatatt attaactttt tgttcgtagg catattttgc
      121 tacatgatct aggtatatat caaaaaagtc atgaggaaaa tctcccatac agccattacg
      181 attcatattg aggctatatt ttcgattagt aagataattc ggaaatatat ttcctattac
      241 tctaagatta tctacttgtg aatcccttct cccaatataa tccccttctt tgactaatga
      301 tggagatttc caagtaaaaa ttaaatcgcc agagaaattt ttcttatcaa aaaacttaaa
      361 aagagattga taaatactat ttgctaattg acaagtgtca gatgtaaatt cataattaac
      421 agcttcatta aaatcaactt cagacatttc aatgtactct tcaatagtaa tattagcttt
      481 ttttgtagtc attagctaat ctcctttaaa atgtgatctt ttcaagaata tttttatcta
      541 aacaatccag caagtcttgg taagaataga cttcgtaagt cggctgggct tgtgtgtgat
      601 tttcgaggtg atgaggatta taccagatag tgtcaatccc cgcattattg ccaccttgaa
      661 tgtcggcggt tagagaatct ccaatcatca gcgtcttttc tttactaaat ccagcaattt
      721 gctggccaat cttttcataa aagagagcat ccggcttttg agtttgcaac tgttctgaga
      781 taaagacttg attgaaataa ggtgctagac cagattgagc caaacgtcct gtctgaatgg
      841 cagtaatgcc atttgtcgca gcatacaagt cataatcacg ctcaatgagg ctgtccaaga
      901 gatcatgagc gcccgatagt gtttgtccct gctgggcgag gtaaaattgg taacgctggg
      961 caagaaaact accgtctttt tcctgtccaa aatgagaaaa taaacgagaa aagcgcgtgt
     1021 taaccagctc ttgtttactg attttcttca gctccaagtc tttccagaga gccttgttca
     1081 taggaacgta ataatcttta taagcctgaa tatccgcaac tccttcttct tttagaagtt
     1141 gggtcaaagc cacatcctca gcagcatcaa aatcaagaag agtgtggtcg aggtcgaaga
     1201 gtagaaattt gtagaacaat ttgaggtttt cctttctgaa aattcattaa aaacattata
     1261 tcataaagca cctcatacaa ttaactaatt taatcactta aaaaaaattc gaacactttc
     1321 tatacaactg acagctcaaa tctttcagaa tagaacaata ctaactatcg agcacccccg
     1381 tcttcataaa tatatgtgta attctagacc tagaattcct ataaactaaa tgctttcata
     1441 ctcttccaag taattgattg ccttaaattt taatttttga aggattctaa agctagaata
     1501 gccccatcac aatcagtttt gattgattca caatttagaa acactatagt ttcactcctg
     1561 ttaaaataaa aaggaactgc ataaagcaat ccctttctaa ttttgaaatc atttacttaa
     1621 cattttatag ttgagataat caatagctta cctataaaaa gagttatagt aaaattcctt
     1681 atttattgat ttcaagctcc gctaactgtg tttgaataac tgacagttct gcaccagcct
     1741 gcagaagagc agctgcatta taggcgcctt ctacaattgg aaccctgttg atgatgatac
     1801 ttttatcact gaaatcagtc accattttta agttcatttt agcagaacct aggtcaaaaa
     1861 aggcaagtaa agtatctgct ggattttcgg aaacaaccct atctacttga tcaaaactcg
     1921 ttccaattcc tccgccctcg gttcctccta cataagtaat cggaacatct ttagctactt
     1981 tactaatcag ttcaacaaca ccttctgcaa tgtgtttgga atgtgaaacg ataacaagac
     2041 caataccaat actttccatc aaaccacccc agtttctaaa atagcagtaa agagtaatcc
     2101 tgatgagaat gatccaggat caatatgtcc aagaaaccat atgctcctaa gacaagagcc
     2161 aacagactgg tcatcaataa tagtattgtt ctttttttca tcattactcc ttaactagtg
     2221 tttaactgat taattagcca gtaaatagtt tatctttatt tacactatct gttaagatat
     2281 agtaaaataa gaacaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtat
     2341 actattctag tttcaatcta ctatattttg cacattttca tgaaaaaaat gagaactaga
     2401 actcacattc tgctctcatt tttcgttttc ccgttctcct atcctgtttt taggagttag
     2461 aaaatgctgc tacctttact tactctcctt taataaagcc aagagactat ctacttctgc
     2521 tgaaatagtg ttattatctt tcgttccgag aagaagacta ctttttagac cagtcaatgt
     2581 ctccacagca ttttgtctaa tactagaatc tgttactttt tctagcaagg cctccgcatc
     2641 tgctatctta gcgttaataa cagaatgctc tacttgagga atttcagcct catctgtagt
     2701 atcttcagct tcttcctctg tctcttccgt atcagtgctt ggtttataaa gattatctgc
     2761 tgaaggattt aaaccagcgt gattctcttt ttcatcagat tcagggtgag ttggctcact
     2821 tacttcatca tgttccttat cttcctcagg tttttctgtc tgaggtttct cctcgtttgg
     2881 tttttccgtt tgattggtat cagcttgacc atttttgttt ctttgaacat ggtcgctagc
     2941 gttaccaaaa ccattatctg aatgcggacg ttcgtttgga tgttcgacat agtacttgac
     3001 agtcgccaaa agatcctcaa gagtataccc cttaggtgcc tcataaaggc cttcgtcaaa
     3061 ccactcaaat ttgatgttat ggtaatggtc ataatgaggt atgattaaac taccgttttt
     3121 gacttctaca gtatattgaa gattgtaagg catacgatca agtggcacct tcttagctgc
     3181 tttcacgcgg ttgtagatag cttctgctcc ttttgcctca gtatttcctg aatcctgatg
     3241 gtctgtcgaa ggaggggtca aacctttctc tttagcataa gcctgggctg ccgctctctc
     3301 agcttcagac aaactatctt ttttaatcca gtggctatgg gtcatatgtg gagttacata
     3361 ggcatccccc tcatcactgg ttatatcacg aggatcaaag atataaccgt cttctgttgt
     3421 gtacttgcct gccaacttgg ctacttgaat ctcatcatca gtgta
//
LOCUS       DAVLHM010000090         3406 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLHM010000090 DAVLHM010000000
VERSION     DAVLHM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.090"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            11..304
                     /locus_tag="VXE45_002073"
     CDS             11..304
                     /locus_tag="VXE45_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEV0790036.1"
                     /translation="MEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAV
                     FESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            614..2002
                     /locus_tag="VXE45_002074"
     CDS             614..2002
                     /locus_tag="VXE45_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV0790037.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEQWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMEDVEK
                     KILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDIDQYKVVSGKLKKLLSDKEKLS
                     PKKWNEEKILLM"
     gene            2328..2501
                     /locus_tag="VXE45_002075"
     CDS             2328..2501
                     /locus_tag="VXE45_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790038.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            2687..3214
                     /locus_tag="VXE45_002076"
     CDS             2687..3214
                     /locus_tag="VXE45_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV0790039.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            3341..>3406
                     /locus_tag="VXE45_002077"
     CDS             3341..>3406
                     /locus_tag="VXE45_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0790040.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
BASE COUNT         1714 a          423 c          546 g          723 t
ORIGIN      
        1 aagattaagt attgaagaac agattgaaaa gaaagaagaa agcattaagc aattacaaaa
       61 tcaaaaaaga cagttgaaga aaaaacttaa tgaacaagaa agaaaagcaa gaaacaaaag
      121 acttatagaa aaaggtgcag tgtttgaaag tatttttgaa gaaagtattg atttaacaaa
      181 agatgaattt tataagttaa taaaaacgtt aaatgatgaa gaaataagat taaacataat
      241 ggaaatttta gaagaaagaa tagatgataa tgtagaaaaa tcatctaaag atgaaataac
      301 ataattgtcc cttggttaca agggcgcaat tatacaccct aaagggtgct tgcgtcctgc
      361 ggagtcaaac ccttgcaggg agcaacaacc attcgctttt taaaagtcaa gggtaaataa
      421 actcgctaag gctcgccctt gacttttaaa atttgaaatg aaagtaacaa ttaagccgac
      481 atactgaaac aacaaaaatt aattcagtag tcggcttttt ttattctatc atttcaaaac
      541 gctcattcac aaagaggata taaaaaaact attaagcctc cacctaaaac aacaaagaaa
      601 ggaagtgata aaaatggcag acagttttca tttttcagta aacataatat caagaggaaa
      661 aggcaaaagt gcagtagcaa gtgcagcata tataagtgga gaaaaaataa aaaatgaatg
      721 ggacggagta acccatgact acacaagaaa agaaaaaata ttagtaaaaa atataatatt
      781 gcctgatcat ataccaaaag aatttaatga taggtctacc ttatggaata aagtagaaat
      841 ggcagaaaaa aattctaatg cacaactagc aagacaattc ataataggac taccaaaaga
      901 gttatcttta agtgaaaata aaaacctggt tgaaagatat ataaaagaaa atttaacatc
      961 acaaggaatg atagtagatt atgcaattca tgatgagagt caagataaaa atggaaatat
     1021 ccattgtcat ataatgacca taatgcgacc aataaacgaa aaaggagagt tcttagccaa
     1081 gtcaaaaaaa gaatatatcc tagatgaaaa aggagaaaaa gtattaaaca aaaatggaaa
     1141 accaaagaca agaaaagtag aactaacaac ctggaacgat acaggcaatg tagaacaatg
     1201 gagagaaaat ttttcagatc tttgtaacaa atatttagaa agagcaggag cagaaaaaag
     1261 agtagaccat aggagtttta aaagacaaaa ttcagattat ctaccgacaa tccatttagg
     1321 atcagcagca agtgcaatgg aaagaaaggg aatagaaact gacaagggaa actataatag
     1381 agaaataaga aaatataatc aacttgtaaa aacaataaaa gaagagataa aaacattaaa
     1441 gggttggata ggaaatttat tagataactt atctactgct tatgaaaaat ttaaggatat
     1501 cgaaagagat aaggtaatag acaaccctaa actttttaat ctaacaaatt atctattaac
     1561 ttattcagaa attcaaaaag aaaaaagtaa atatctaaaa ggatatgcaa aaactaataa
     1621 agaaaaatat gacttcaaaa agctaacaag tgcatatagt tatttaagaa aaaacaacat
     1681 agaaaccata ggtcagttac aaacaaaaat agaaacttta aagtctaata gttataggct
     1741 aaataaaaaa gcaaagacaa tccataaaga aatggaagat gtagaaaaga aaattctata
     1801 ctatgaaatc tacaaagcca aaaaagaagt ttatgaagaa tatcaaaaga aaaatatatt
     1861 cacaaaagaa gcattttata acaaacataa gaaagatata gaccaatata aagtagtaag
     1921 tgggaaatta aaaaaactcc tatcagataa ggaaaaacta agtcctaaaa agtggaatga
     1981 agaaaaaatt cttttaatgt aaaatcttga agaaataaat aaagaaaaag acaagataaa
     2041 agatgaatac caggaaatta atcatataaa atattcagta gattttgtaa acaaagaact
     2101 tggtatagat ttatccatag aaatagataa gctaataaaa cagggagaaa aaccaagtgt
     2161 aatagcacag attaaaaagt tccaagacca agtcaataaa gataatgaat acagagaaat
     2221 gatgaaaaac aagaaaatgg atcaagaaag ataagacctg gtaaaaatat cttatccaag
     2281 ctataatatg accaaacaac taaagtcaga tctaggaggt aatagagatg aataaaaggc
     2341 aagagctaat agatgaactc ataaaagcaa atgaagatgg aacatacaaa acctataaaa
     2401 gcacagaaga aataaaagca atgaacaatg aagaaataca gattatatat tccaacatga
     2461 aaaactatct atcagacaaa agaacacaca taaactatta aaggtggaaa ggtagtgtaa
     2521 gctattttta aaagtataaa aggtacaaag acctaagaaa tatataaaaa catcaaaata
     2581 aagtattcca ccaccaagaa caataaaata aaaacaagca aagggaagta tagaaaaatt
     2641 aaaacctata cttccctttt ttaattcaaa caaaggagag aaaagcatga taaacgaaga
     2701 aataagcaag gaagcaggtc aagcagcaca aaccataata tcatacacaa taaaggcaac
     2761 aaaagaatca atcaatttag aaaaagaaat aagaaaaaag atgaatgaaa ctttagaaaa
     2821 agcaaatgga aacttaaaaa gtcttatggg cgatgaaatg aaaataaaag atctctacaa
     2881 gaaaggacaa ctagaaaata taagcataga tcaaatcgac ctcaaagact taaaaaaaga
     2941 actaaacaaa cttggagtaa gtttctcagt aatgaaaaac aaagaaagca aaaactatga
     3001 aatattcttc caagccaaag acataaaagt aatggaatat gcctttaagc aagtcatagc
     3061 caaggaaaat aaaaaagaaa aagaaagtat cctaaaacaa ataaagaaat acaaagacct
     3121 atccaaaaac aaagataaga caaaagaaaa aggaaaaagg aaagtaaaag aaaaagtaaa
     3181 accaaacaaa aaagatatga ccagagaaat ctaaagggag taacgaaaag ttacaccctt
     3241 aaataaccat aataacaaga cttccgaaaa acagaagtcc agaattccga aaatcggaaa
     3301 tcaagaattt cgattatcga aaatcaagaa aggagcagat atggcaacaa acaaaagata
     3361 ctattggata aaattaaaag aagaattttt cacagacaaa aggata
//
LOCUS       DAVLHM010000091         2907 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLHM010000091 DAVLHM010000000
VERSION     DAVLHM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.091"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..156)
                     /locus_tag="VXE45_002078"
     CDS             complement(<1..156)
                     /locus_tag="VXE45_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0790041.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLN"
     gene            250..1470
                     /locus_tag="VXE45_002079"
     CDS             250..1470
                     /locus_tag="VXE45_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEV0790042.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            1483..2664
                     /locus_tag="VXE45_002080"
     CDS             1483..2664
                     /locus_tag="VXE45_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0790043.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
BASE COUNT          989 a          389 c          617 g          912 t
ORIGIN      
        1 gtttaacaga atataaaaat gattaataga taattttgta atgccatttt cgaaacgaga
       61 aatagttgat tcactaattt cattacatga taaatcttta aggcgaaaat tttttgaaat
      121 acgaatatcc tttaaaactg ctccgaaatt ttccataatg ttcctcttcc atttctgcaa
      181 aaaataaaac gcttgttttt tatttatgat atgattatac aaaaataaaa tagaaaggac
      241 aataatatca tgaaaaaaat tttattgtca acagttgctt tattaagctt agtagcatct
      301 ctgctagcaa ataatccagt ttctgctcaa gaatcatcct ctcaagcaac ttatagtaag
      361 tcaagtggaa gttggataaa atctggtaac cgttggtggt ataagcattc tgatggttct
      421 tatactacaa atggatggga aaaaataaat ggtacctggt actattttga tagtgaaggt
      481 tggatgaaga caggttggat taaagaatat gggaaatggt attacctaga tgatagtggt
      541 gctatgaaaa ctggatggtg tttggtttct ggtagctggt attatttaaa tagtagcggt
      601 gtaatgcaaa cgggactaca gactatcaat ggaaaacaat attatttagc tgccggcggt
      661 gctatgcaga caggttggca caatatcgga gatgatacct atttctttgc taatagtggg
      721 gaaaatcaaa atatcaatcg tcgtgcttta gttcttggtg aaacatcaac gagagcagta
      781 cctattgcag atgttaatgc tatggaaaag gtttttaata accaaaactt tagtgaagtt
      841 gttcgtttcc cagatagaac aaaatccgag ataattgcaa aaatgcaaga gctttttgaa
      901 tcttctagcg aaggcgatgt gaactatctt tactttactt gtcatggagg aagagatgga
      961 agaatctata ttggtagtga tggcctagca ttttctggtt gggaattggc gtccgttttg
     1021 aaacaataca aaggtaagtt tgttgttatg ctggattgtt gtcatgctgg aacaattatt
     1081 tctaaagata atacaggtga aggcaatgaa ggagcctcta cggaatattt tgatttagat
     1141 gaatttgtat caggattttc taatatggat ggtaacgaaa aatcaggtga gatgattgac
     1201 tctaaatttt tagtattatg ctcatcaaga ggtgcagaat actctagtgg tggatcatta
     1261 agtttagcga ctaaatattg gtctttaggt tcaggatgga atcctctaca gaattcacaa
     1321 gcatatttag cagcagacca aaataataat cgcagaatca cattaaatga attgtataca
     1381 tactctcgtg aacaagtttt gaaacaaaat tctaaccagc atattgaagt ttatcctgac
     1441 aacagtcaat ttgtgttatt taagaaataa gggggcaata aaatgaaagt atcaaaaaaa
     1501 attacactat ttagtttgtc ttttgcaggt tttgttttat tgactttacc tcaagcagga
     1561 aaggcttttg aacttaaaga agactgggca tttaaaggtg gcattcgata cgagaatggg
     1621 aaagtcagca aaattaataa tggatatgaa gtaaatatta aagtgttaga tttacctagt
     1681 actagcgcaa tcgaatggac agttagattg aatggagaaa agcaaaatac taacttctta
     1741 gcggaggaaa gaactgtatc taaaactgaa gataagggac gtttcttgca cttttatatc
     1801 ccctatggat atcgtgggga tattgtagta gaggctaaga gtggaaacga agtgaagact
     1861 tggtctacta aggtagttga cgatgtttat tcagattctg ctaagagtgg ctactttatt
     1921 ctcgatgggg aacaaatctt agaaagttca tgggattccg taaatgagtc ttatattgca
     1981 acgcttccaa ctgtaacatc aggaaaaact gttgttgctt ggcgtgaaaa aggaactctt
     2041 aatttaatta aaccaggaag aattgctcgg caatataata gcagtggatc atatgtagaa
     2101 ctttctccaa tctttgaaac tgctagttgg ctaaaatcaa accaaaactg gtactatcaa
     2161 aaacaaggtc aattagttca aaattcttgg atcaaggatc agggaagctg gtactttatg
     2221 gatgatgaag gggttatgtt taatcaaaca tggctacacc aaggtggaag ctggtatgcc
     2281 tttaagtcat caggagccat gatttcagct gattggttgt atgataatgg ttcttggtat
     2341 tacctaaagg actcaggttc tatggtaaca ggatggctta aaaatggagg ctcttggtat
     2401 tacctaaaca agtcaggttc aatggctaca ggttggatta aagatagtgg aacttggtat
     2461 tatctaaaga attcaggctc tatggcgaca ggctgggtga aagatagtgg ctcttggtat
     2521 tatctaaaga actcaggttc aatggcaaca ggttgggtca aagataatgg taagtggtac
     2581 tatctcgcat catctggtaa tatgcttcgc aatacacgca caccagatgg ctattatgta
     2641 gatggcagtg gcgcttggaa ataaattttt aaaagagaaa atctactgag aaggtagatt
     2701 ttctttttag ttaatgaata tagaataaag tagatcagga ctggtctatt ttattttgta
     2761 actattaatg aatagtctta atgatgaagt tactttctga agatatttaa ttgtgttgag
     2821 atttgataaa actatagcgg attgaaataa gatataaaca aagagattat ggaagtcaaa
     2881 ttaatttcta aaaacgtttt aaaatcc
//
LOCUS       DAVLHM010000092         2830 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLHM010000092 DAVLHM010000000
VERSION     DAVLHM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.092"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..143)
                     /locus_tag="VXE45_002081"
     CDS             complement(<1..143)
                     /locus_tag="VXE45_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0790044.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEA"
     gene            348..536
                     /locus_tag="VXE45_002082"
     CDS             348..536
                     /locus_tag="VXE45_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0790045.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            693..1058
                     /locus_tag="VXE45_002083"
     CDS             693..1058
                     /locus_tag="VXE45_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0790046.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            1061..2728
                     /locus_tag="VXE45_002084"
     CDS             1061..2728
                     /locus_tag="VXE45_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0790047.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT          901 a          516 c          624 g          789 t
ORIGIN      
        1 gcttcttttc ctttctgttg ataggctagt agcagacgat tgatttgtct ttcagaaaga
       61 ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc ttttatcaca
      121 agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact attctaccaa
      181 atgtgacatt ttcacgttcg atttactaaa gacattatca cattcgaatc acaacacaaa
      241 taaaaaatct tccaattccc ttgcaaaaaa caagaaagtg tgataacata gtacggtatg
      301 tggtgctagc acatccgcta tattagatct aataggagga aaacacaatg gctaaagtat
      361 gttactttac aggtcgtaag actgtatcag gaaacaaccg ttcacacgcg atgaaccaaa
      421 caaaacgtgc cgtaaaacca aaccttcaaa aagttactgt tcttatcgat ggtaaaccta
      481 aaaaagtttg ggcttcagct cgtgctttga aatcaggtaa agttgaacgc gtttaataat
      541 aaaagcaaag gagaccttag ggtctttttt cttttattgt gggtataaca tcgtttgaaa
      601 aatagagtaa atatccgctg atacatcatt ctgcttttac acttgggctg aaatatgata
      661 aaatagagta tcaactagtt gaggtaaaaa ggatgactgt aaaaattaat acaaaagatg
      721 gtcaaatcga actaacagat gaagtgattg caaccgtcgt aggtggagca gcaactgaga
      781 tttttggtgt ggtcggtatg gctagtaaaa atgccctcaa agataatttc caagccctgc
      841 taggtaagga aaattattct aaaggtgtcg tcgtaaaggc agccgaagat ggcagtattg
      901 cagttgatgt atataccgtg ttaagctacg gaacaaagat tagtgaagtg tcaaaaaaca
      961 ttcaagagcg tgttgccttt agcttggaaa accagcttgg aattactgct cagactgtaa
     1021 atgtctacat tcaaaatatc aaagttgtag gagaataacc gtgtcaaaga ttactactag
     1081 cttatttcaa gaaatggtgc aggctgcatc aactcgcttg aataagcaag ctgaatatgt
     1141 caattcatta aacgtctttc cagttccaga tggagatact gggacaaata tgggaatgac
     1201 cattgaaaat ggtgctaaag aagttgcaga caagccagct tctacagttg gagaagtagc
     1261 gagcattctt gccaaagggc ttttgatggg tgcgcgtggg aactcaggag tgattacatc
     1321 tcagcttttc cgtggatttt cccaagctat caaggataaa gacgagttaa caggtcaaga
     1381 cttggctctg gccttccaat caggtgtgga agttgcctat aaggcagtga tgaaacctgt
     1441 tgaaggaacg attttgacag tttctcgtgg agctgctatc ggtgctaaga aaaaagctga
     1501 gcaaacagat gatactgttg aagtcatgcg cgcagccttg gaaggtgcta aaacagctct
     1561 agctaaaaca ccagacatgc ttccagtatt gaaagaagtt ggcgttgtgg actcaggtgg
     1621 tcaaggattg gtcttcatct acgaaggttt cctttcagcc cttactggcg aatatattgc
     1681 atctgaggac tttgtagcga ctcctgccaa catgagtgag atgatcaatg tagagcatca
     1741 taagtctgta gctggtcacg tagcgactga ggacatcacg tttggttact gtactgaaat
     1801 catggtagct cttaagcaag gtccaaccta tgctaaagat tttgactacg atgaattccg
     1861 taactacttg gatgagcttg gggattctct cctcgttgtt aacgatgatg aaattgtcaa
     1921 agtccatgtt catacagaag atccaggact tgttatgcaa gaaggtctca aatatggtag
     1981 cttggtcaag gtaaaagttg acaatatgcg taaccaacac gaagcacagg ttgagaaaga
     2041 agctactcaa gttatcaagt cggctgaaga aaaagagtat gctttgattg ctgtggtggc
     2101 tggtaaaggt ctagcagata tcttctgttc tcaaggcgtg gattatgtta tcgaaggcgg
     2161 tcaaaccatg aacccttcaa cagaagactt tatcaaggct gttgaacagg tcaatgcccg
     2221 taacatcatc ttcttgccaa acaacaagaa catcttcatg gcagctcaat ctgcggcaga
     2281 agttttggag caaccagcag tagtggtaga ggctcgcact cttcctcaag gtatgacaag
     2341 tcttcttgcc tttgatccaa gcaagtccat tgaagaaaac caagagcgta tgacagctgc
     2401 tcttagcgat gtcgttagcg gaagcgtcac aacagccgtg cgtgatacaa cgatcgatgg
     2461 cttagaaatc catgaaaacg ataatctagg tatggtggat ggaaaaattc ttgtgtcaaa
     2521 ccctgatatg caccaaacat tgactgaaac cttgaaacat atgttggatg aagacagtga
     2581 aatcgtaacc ttctatgtcg gtgaagacgg aagcgaagaa cttgccaatg aaatcgctca
     2641 agaaatcgta gaagaattcg aagacgttga agtcgagatt caccaaggtc aacaacctgt
     2701 ttacccatac ctatttagtg tggaataaga ttaatgaagg actgagaaat cagttctttt
     2761 ttctttttta gtaaatgaaa tcggtatctt tttaataaaa acaaaaataa cattcataaa
     2821 taaacgttaa
//
LOCUS       DAVLHM010000093         2730 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLHM010000093 DAVLHM010000000
VERSION     DAVLHM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.093"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            112..294
                     /locus_tag="VXE45_002085"
     CDS             112..294
                     /locus_tag="VXE45_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0790048.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            304..669
                     /locus_tag="VXE45_002086"
     CDS             304..669
                     /locus_tag="VXE45_002086"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0790049.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            666..1844
                     /locus_tag="VXE45_002087"
     CDS             666..1844
                     /locus_tag="VXE45_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0790050.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            2013..2565
                     /locus_tag="VXE45_002088"
                     /pseudo
     CDS             2013..2565
                     /locus_tag="VXE45_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1038 a          395 c          477 g          820 t
ORIGIN      
        1 ttatttataa caagaggata gaaatgaccg aattagaaag aaaaaatcga aaaattagct
       61 aagaaatatt ctgataactt aaacatcaaa gttcaagaga gagttcgtga aatggcaaat
      121 gataataaga gccattattt gatatacaga gttttaggta tttcatttga agaaggagaa
      181 aatatcgatt tgtatcaaaa taaaggtcgt tttttataca aatatgctgg ttcattttta
      241 gaagaagctg cagtactatc ctttaacgaa aaatttggta cagaaaatac ttaaaaagtt
      301 aacattccta attctgaaag tacaaaacct aagacttttg aaattgattg tttagtcgga
      361 gaaaaacacg catacgaaat aaaatggtgg gatgcaacta cagatggaga ccatataact
      421 aaagaacaca ctagaataaa agttattcat aacaaaggat atataccaat tcggttaatg
      481 ttctactatc caaatagaac tcaagctata aaaattcagc aaactttaga aacattgtat
      541 aacggtattg gagggaaata ttattatgga gattctgcct gggaacattt aagagcagtg
      601 accggtattg atttacttag tattctaaca gatattgcaa ataaaaaaac aggggtaaaa
      661 tcaaaatgac agtattaaaa ggagataact tagaaatatt aaaaactatt gaatcctcaa
      721 gtattgattt aatctatatg gaccctcctt tctttacaca gaaaacccaa aaattatcta
      781 ataacaaaaa tattatgtat tcattcgaag atacgtggac ttcgattgag gattacaaag
      841 aatttttgtc tgtaagatta gaagaatgca aaagagtgct aaaaaatagt ggcagtattt
      901 tcgttcattg tgataaaatt gcaaatcatc atattagatt aattttagat aatatctttg
      961 gagcagatat gtttcaaagc gaaattatat ggaactataa acgatggtct aattcaaaaa
     1021 agggattatt gaacaatcat caaaacattt acttttattc aaagtcaaaa gattttaaat
     1081 ttaatacaat ttttacagag tattcttcta ctacaaatat cgaccaaata ctagtggaac
     1141 gaaaacgaga tggaaactct aaaactatat ataaagttga taataatggt aactatattc
     1201 tagcaaaaga gaaaaatgga gttccccttt cagatgtttg gaatatacca tttcttaatc
     1261 caaaagctaa agaaagagta ggttatccta cacaaaaacc tattctgtta ttagaacaaa
     1321 ttataaagat tgctactgat aaaaatgata tagttttaga cccgttctgt ggaagcggaa
     1381 ctactttagt agcctccaag attttgaata gaaattatat ggggattgat ttatctgagg
     1441 aagctatcaa tataactcag caacgtctgg aaaatgttat aaaaacaagt tcaaatttat
     1501 tgaataaagg aatcgaagca tatagaacca aaactgagga agaggaaaac attcttaaat
     1561 tattacaggc aaaaattgtt caaagaaata aaggaattga tggtttttta cctaaacatt
     1621 ttcaaaaaaa accgatacct ataaaaattc aaaaaaataa tgaatgtctg aatgagagta
     1681 tctctttatt acagaatgct ataaactcca aaaaacttga ttttggagta gttataaaaa
     1741 ctcattcaga taatttatta tttgattttg atacgattcc tgaaaatata atagtagttg
     1801 accattttga acttacaatc gaaaaatggt taagtaaaag ttaacagtta ctatagtttg
     1861 caaattattt acagaaagaa caagaattcc taggagatta ttctggctat gttcattgtg
     1921 acatgttgcg gcagtaactt aggactttag tcctctagtt ctgcctatgc gatagcagtc
     1981 caaagtttag gagtaaggcg acgctaagct tggtaaactg cgaacagcta gaagcttatc
     2041 gtcaactgga agaagctgca cttgttggat gttgggcgca tgtgagaagg aagttttttg
     2101 aagcgacccc caagcaagca gataaatcat ccttaggagc taaaggttta gcttattgtg
     2161 atcagttatt ttccttggaa agagactggg aggctttgcc agctgatgaa cgactacaga
     2221 aacgtcaaga acatctccaa cccctaatgg aagacttctt tgcttggtgc cgccgtcagt
     2281 cagttttagc aggttcaaaa ctaggaaggg caattgaata cagcctcaag tataaagaaa
     2341 cctttaagac cattttaaaa gacggacatc tggtcctttc caataatcta gctgaacgcg
     2401 ccattaaatc attggttatg ggacggagta aaagagtcca gtggactctt ttagcctgag
     2461 ctcagtttaa aaaagcgagg gtggttattt tctcaaagtt ttgaaggagc taaagcaaga
     2521 gctattatta tgagtttgtt ggaaacagct aaacgtcatc aattatagtg cgttgaatct
     2581 ataacagtac gcatcgactg ctaaaatatt tctataaatc aattttcctt tcctaatcga
     2641 tttgttcata tcttatttca atccattata aatagcgaga aatatctatc ctatcttcta
     2701 gaatgtcttc caaacgagga aactctcgta
//
LOCUS       DAVLHM010000094         2469 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLHM010000094 DAVLHM010000000
VERSION     DAVLHM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.094"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..2297
                     /locus_tag="VXE45_002089"
     rRNA            <1..2297
                     /locus_tag="VXE45_002089"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            2374..>2469
                     /gene="rrf"
                     /locus_tag="VXE45_002090"
     rRNA            2374..>2469
                     /gene="rrf"
                     /locus_tag="VXE45_002090"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          689 a          499 c          728 g          553 t
ORIGIN      
        1 gaaccggcga gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac
       61 cgagtctgaa tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca
      121 tgagcaggtt gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag
      181 tgcttggatg acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct
      241 ctccgaaata gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt
      301 tgggtgaggg gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta
      361 tggtcggcag tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc
      421 accagctaag gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac
      481 taggatgtta gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga
      541 gtgaccctgc gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt
      601 tataggtatg gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga
      661 acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc
      721 gtaagactaa ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag
      781 agaccgaaag gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg
      841 atggagggac gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga
      901 ggtgtgaatt gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt
      961 tagtagcgaa gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc
     1021 tacccgtacc gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa
     1081 ctctcgttaa ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgacttt
     1141 aagtcagccg cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa
     1201 atcgtaagat gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc
     1261 ttagcgtaag cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt
     1321 cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt
     1381 tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac
     1441 ccgcgacagg acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta
     1501 ccacatgtac aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc
     1561 tgttgggata ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga
     1621 gacagtgtct gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc
     1681 ccaaaggttc cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct
     1741 tgactgcgag agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc
     1801 cgtatggaag ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc
     1861 ccccaagagt tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg
     1921 gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg
     1981 ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg
     2041 atctgctcct agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc
     2101 caaaggcatc gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg
     2161 aaacccacct caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga
     2221 tcaggtagat aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag
     2281 ctcgaggact tatccaaagt aactgagaat atgaaagcga acggttttct tgaattgaat
     2341 agatattcaa ttttgagtag gtattactca gagttaagtg acgatagcct aggagataca
     2401 cctgtaccca tgccgaacac agaagttaag ccctagaacg ccggaagtag ttgggggttg
     2461 ccccctgtg
//
LOCUS       DAVLHM010000095         2400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLHM010000095 DAVLHM010000000
VERSION     DAVLHM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.095"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..353
                     /locus_tag="VXE45_002091"
     CDS             <1..353
                     /locus_tag="VXE45_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0790051.1"
                     /translation="PIKFNVSGNKGQKNNIELIAKQRSFIDYWAKYVSYLPFPTPEFF
                     LANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQEQRRAVSKIQPES
                     SMFQCIKEKLEALF"
     gene            733..1536
                     /locus_tag="VXE45_002092"
     CDS             733..1536
                     /locus_tag="VXE45_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0790052.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1652..2400)
                     /locus_tag="VXE45_002093"
                     /pseudo
     CDS             complement(1652..2400)
                     /locus_tag="VXE45_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          742 a          414 c          442 g          802 t
ORIGIN      
        1 gtccaattaa atttaatgtt tcaggtaata aagggcaaaa aaataatatt gaattaattg
       61 cgaaacaaag aagctttata gattattggg ctaaatacgt ttcttatctt cctttcccaa
      121 ccccagagtt ttttttagct aatttgtgta acagcgtaga tagggaaggt tatgattttt
      181 ctaaagatgg caacggaaaa gaatatttta gaaaaaaaac tcaagtagcg ttaggaatag
      241 agaatataac ttctgaagat attttccagg agcaaagaag agctgtttca aaaatacagc
      301 cagaatcatc aatgtttcag tgtattaaag aaaaattaga ggcattgttc taattcctta
      361 gattaggtac tacataacaa attttttaaa ttcaaacccg caccaaaaac aacattgcaa
      421 ctttcttctc aggtaatgtg ttgggatttg aacagaccaa cgagttcata gaggtgtatg
      481 ccaatgagtt tgataagtat gcgcgtcaga cttattagtt catttatcca gatatatctc
      541 gataatcata ttatttagtc aaagaacatc ccatatgagg gcatgaaatg ctaagtttag
      601 cttgctcact attaagatga agtatatata tttcatagaa cttattgtga aggattttta
      661 taattttcgc caattccata cccatttcac catttaccga tgacacagaa aaacaattga
      721 aaggatattt ctatgcaacc aacttacaac attgacaatc caaacttgtc ttatgaagcg
      781 aagcgtgatt tatggcggat aggttttggt ctgcagaaag ttgacaatct agtgccatca
      841 gcgtatatgg aatctttggc tgagaaacag tcccggggag aactgactta tgagcaggtt
      901 tatgaggatg caacggctta tcaccatact attgatgcaa gtacggaaga ggcagacttg
      961 gtttctctac gtattgtaga actattgtct cgaagaggct ttagctttag tcctgcgacc
     1021 ttacttgcta ttcataagga gttgtttcaa gatatatttg aaccctctat tccggtgggg
     1081 caatttcgtc agaccaatat cacaaagaat gaacctgttt tgaatggtga aagtgttgtg
     1141 tactctgatt actccatgat tcaaatgacc ttagattatg attttaatca ggaaaaacaa
     1201 gttgcatatg cgacactaac tcaggcggat gtggttaaac aaatccagca ttttatttca
     1261 ggaatctggc agattcatcc atttcgcgaa ggaaacactc ggacagtaac ggtctttttg
     1321 attcagtatc ttcgtgagtt tggttttgat attgataata caccatttca gcaacattcc
     1381 aaatattttc gtgatgcctt ggtattagat aatgcaaaga ttttacagcg acgtcctgag
     1441 tttttaacag ctttttttga aaatctcttg ctcggtggtc aaaatgattt gtcttcagaa
     1501 aaaatgtatc tagatttaga ccttgatttt tcataatcca aatactgagt aaacattgaa
     1561 ttttaggcaa aaatgaagta aatattctca caagaaaacg tatatcatca aagttttagg
     1621 tgtactgacc ccaaacagtt agacaattaa tttatccgaa ggatttagtt ctgtattgca
     1681 caggactaag tccttttagt tttaccttaa ttcgtttatt gttgtagtaa tcaatatagt
     1741 ctacaatagc ttgttccaat tgcttaagcg actgaaacga cttctcataa ccgtaaaaca
     1801 tttccgattt cagaatccca aagaaagatt ccatcatacc gttgtcttgg ctgtttccct
     1861 tgcgtgacat ggatgcttga actcccttac tctctaggaa ccgatgataa gaatcgtgtc
     1921 ggtattgcca gccttggtca ctatggagaa tcgtattctc atagtgcttc tctgtgaatg
     1981 cctgttccaa cattgtttgt acttgttcta agttgggtga agttgaaaga ttataggcga
     2041 taatttcgct attaaagcca tctaaaactg gtgataagta aagcttttga gtacttgctg
     2101 gaatggcaaa ttctgtcaca tctgtgtagc actgttccat tgttttagag ccttcaaatt
     2161 ggccttgaat gagattctct gccttcttgc caacgtctcc tttatgagaa gaatattttc
     2221 gtttctgtcg cattttagct tgtaaattga gtacttcatc aagtgttgaa ctcttttatg
     2281 atttaccaga taaccacgat ttcttagttc taaataaatc cgacgataac cataatttcc
     2341 cttgtgttcg ataaagatgg attgaatttc agctttaagc tcttggtcct tatctgtttt
//
LOCUS       DAVLHM010000096         2151 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLHM010000096 DAVLHM010000000
VERSION     DAVLHM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.096"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..562)
                     /locus_tag="VXE45_002094"
     rRNA            complement(<1..562)
                     /locus_tag="VXE45_002094"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(687..759)
                     /locus_tag="VXE45_002095"
     tRNA            complement(687..759)
                     /locus_tag="VXE45_002095"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(724..726),aa:Ala,seq:tgc)
     gene            complement(811..>2151)
                     /locus_tag="VXE45_002096"
     rRNA            complement(811..>2151)
                     /locus_tag="VXE45_002096"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          461 a          641 c          455 g          594 t
ORIGIN      
        1 tgttgtaggc acacggtttc aggttctatt tcactcccct cccggggtgc ttttcacctt
       61 tccctcacgg tactggttca ctatcggtca ctagggagta tttagggttg ggagatggtc
      121 ctcccagatt ccgacgggat ttcacgtgtc ccgccgtact caggatactg ctaggtacaa
      181 agactatttt aaatacgagg ctattactct ctttggctga tcttcccaaa tcattcttct
      241 ataatctttg agtccacatt gcagtcctac aaccccgaag agtaaactct tcggtttgcc
      301 cttctgccgt ttcgctcgcc gctactaagg caatcgcttt tgctttctct tcctgcagct
      361 acttagatgt ttcagttcac tgcgtcttcc tcctcacatc cttaacagat gtgggtaaca
      421 ggtactacct gttgggttcc cccattcgga aatccctgga tcatcgctta cttacagcta
      481 cccaaggcat atcgtcgttt gtcacgtcct tcgtcggctc ctagtgccaa ggcatccacc
      541 gtgcgccctt attaacttaa ccttattttc tgacctttca gtcataaact cttattaata
      601 ctacagcgtt ttcggtttat tttcttgtta ctatttgata tagatattca attttcaatg
      661 tgcattactt ggtgatctct caccaatgga gcctagcggg atcgaaccgc tgacctcctg
      721 cgtgcaaagc aggcgctctc ccagctgagc taaggcccca caagacctct caagactaaa
      781 caagaccaat gcgcagttcc ttatccttag aaaggaggtg atccagccgc accttccgat
      841 acggctacct tgttacgact tcaccccaat catctatccc accttaggcg gctggctcct
      901 tacggttacc tcaccgactt cgggtgttac aaactctcgt ggtgtgacgg gcggtgtgta
      961 caaggcccgg gaacgtattc accgcggcgt gctgatccgc gattactagc gattccgact
     1021 tcatgtaggc gagttgcagc ctacaatccg aactgagact ggctttaaga gattagcttg
     1081 ccgtcaccgg cttgcgactc gttgtaccag ccattgtagc acgtgtgtag cccaggtcat
     1141 aaggggcatg atgatttgac gtcatcccca ccttcctccg gtttattacc ggcagtctcg
     1201 ctagagtgcc caactaaatg atggcaacta acaatagggg ttgcgctcgt tgcgggactt
     1261 aacccaacat ctcacgacac gagctgacga caaccatgca ccacctgtca cctctgtccc
     1321 gaaggaaaac tctatctcta gagcggtcag agggatgtca agacctggta aggttcttcg
     1381 cgttgcttcg aattaaacca catgctccac cgcttgtgcg ggcccccgtc aattcctttg
     1441 agtttcaacc ttgcggtcgt actccccagg cggagtgctt aatgcgttag ctacggcact
     1501 aaaccccgga aagggtctaa cacctagcac tcatcgttta cagcgtggac taccagggta
     1561 tctaatcctg tttgctcccc acgctttcga gcctcagcgt cagttacaag ccagagagcc
     1621 gctttcgcca ccggtgttcc tccatatatc tacgcatttc accgctacac atggaattcc
     1681 actctcccct cttgcactca agttaaacag tttccaaagc ctactatggt taagccacag
     1741 cctttaactt cagacttatc taaccgcctg cgctcgcttt acgcccaata aatccggaca
     1801 acgctcggga cctacgtatt accgcggctg ctggcacgta gttagccgtc cctttctggt
     1861 aagataccgt cacagtgtga actttccact ctcacactcg ttcttctctt acaacagagc
     1921 tttacgatcc gaaaaccttc ttcactcacg cggcgttgct cggtcagact tccgtccatt
     1981 gccgaagatt ccctactgct gcctcccgta ggagtctggg ccgtgtctca gtcccagtgt
     2041 ggccgatcac cctctcaggt cggctatgta tcgtcgcctt ggtgagccct taccccacca
     2101 actagctaat acaacgcagg tccatctggt agtgatgcaa gtgcaccttt t
//
LOCUS       DAVLHM010000097         1953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLHM010000097 DAVLHM010000000
VERSION     DAVLHM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.097"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            3..1640
                     /locus_tag="VXE45_002097"
     CDS             3..1640
                     /locus_tag="VXE45_002097"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0790053.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            1741..>1953
                     /locus_tag="VXE45_002098"
     CDS             1741..>1953
                     /locus_tag="VXE45_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEV0790054.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDP"
BASE COUNT          723 a          266 c          347 g          617 t
ORIGIN      
        1 atatgtcaat ttttattgga ggagcatggc catatgcaaa cggttcgtta catattggtc
       61 acgcggcagc gcttttaccg ggggatattc ttgcaagata ctatcgtcag aagggagagg
      121 aagttttata tgtttctgga agtgattgta atggaacccc tatttctatc agagctaaaa
      181 aagaaaataa gtctgtgaaa gaaattgctg atttttatca taaggaattt aaagaaactt
      241 ttgaaaaatt aggttttaca tatgacttgt actcgcgaac agattctcca ctacatcatg
      301 agatagtaca agaattattt ttgcaattat acgagaagaa atttttgtat acaaaaaaaa
      361 ttaaacaact ctattgtaca tttgataatc aattcttacc tgataggttc gttgaaggaa
      421 aatgcccgaa ttgtggaacc cattcaagag gagatcaatg tgataattgc tcagcaattt
      481 tagatcctat agatttagtt gataaaagat gttctatttg ttccaatgaa ccagaagttc
      541 gtgagacaga acacttttat tatgttttta gtgagtttca aaatttgtta gagacttact
      601 taaatgatgc tgaagaaaca gtgagatggc gaaaaaatgc aataaatcta actaaaaggt
      661 atttacggga aggtttacct gatcgagctg ttactcgtga tctaccaaat gggattccag
      721 ttcccattga tggttttaga gataaaaaaa tatatgtctg gtttgaagcg gtagcaggtt
      781 actacacagc aagtgttgat tgggcgcaaa aacttcaaaa taatattact gatttttgga
      841 acaatcggac aaagtcatat tatgttcatg gaaaagataa catcccattt catactatta
      901 tttggccggc aatactctca ggtttagaaa tagagcctct tccagagtat attatttcta
      961 gtgaatattt aacgttagaa aacaaaaaaa tatcaacaag taataattgg gctatatggc
     1021 ttaacgatat cataaaaaaa tatgatgctg attcaatccg atacttccta acaataaatg
     1081 ctcctgagat gaaagatgca aatttttctt ggagagaatt tatttatagt cataactcag
     1141 aattattagg atcgtacggt aattttatca ataggactct aaagtttatt gaaaagtatt
     1201 ttgaatctga aatacccact aaatatctcg aaggagaaat tttatataat ttgaaagaat
     1261 tatatacaac agtaggtaat ttagttgaga gcgggcatat gaaacaggca ttagaagaaa
     1321 tttttgaata tattagatcg gctaataaat tctatgatga tatgaaaccg tgggcattgc
     1381 gagagtccga tattgaaaaa tgtaaagaag tcttagctac ttgtgtaatc attatactta
     1441 atttaggaca aatgttaaat ccattcattc ctttttctgg taaaaagatt gaggatatgt
     1501 ttaaaacaaa gctaaatact tggaattata tttcaaacct tcctaacaag ctatcagatg
     1561 tatcaatgtt gtttgatagg attgatttga aaaaaattga cgaggaagtt ttagaattgc
     1621 aacaaacatc cagtagataa ttcaaaaata ctcgaaagta gcctttttta atttaaatta
     1681 acaaccggag atgttgaata aaataaagat ggttttttga gcatattatg gagaaaagca
     1741 ttgaataatc taactttact aaaagaatat aattttagag atcttggaaa ccacctcact
     1801 caaacaggac aaaaaataaa acctaaaaca ttattccgtt caagtaaact atttggaatc
     1861 tctaaaattg atgtcgattt gttacagagc tatggaataa caaaagtcat tgactttcga
     1921 tcagcgaatg aaataaaaaa agctccagat cca
//
LOCUS       DAVLHM010000098         1895 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLHM010000098 DAVLHM010000000
VERSION     DAVLHM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.098"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            2..604
                     /locus_tag="VXE45_002099"
     CDS             2..604
                     /locus_tag="VXE45_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HEV0790055.1"
                     /translation="MTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIANNYQIEIP
                     NCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVLLFTSYKL
                     LGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAFVIIYFPL
                     SQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLRK"
     gene            588..776
                     /locus_tag="VXE45_002100"
                     /pseudo
     CDS             588..776
                     /locus_tag="VXE45_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            813..>1895
                     /locus_tag="VXE45_002101"
     CDS             813..>1895
                     /locus_tag="VXE45_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEV0790056.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISI
                     KVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILF
                     LLVNFRTFIQLPVDIFISMIIFLMLWI"
BASE COUNT          646 a          219 c          312 g          718 t
ORIGIN      
        1 tttgactaat ttccaaaact ttccaataac gctaaacatt cttttatttt ggttgcttgt
       61 tgttattata tctgcaacga tacatgaatt tagtcatgca ataattgcta ataattatca
      121 aattgagatc ccaaattgtg gaataatgct acttttgttt aatttggctt tttttgtaga
      181 tttaagtggg gtgcaattcc taaaaaataa aaaacaattt ttgaaaatta tgttagcagg
      241 aattgcttca aattcgattt tatcacttac aggtttactt gttttattgt tcacatcgta
      301 taaattgctt ggactcttat tttttatcat taacttaggt atgattttta ttaattcaat
      361 tccttttttt cagtatgata gtggtattat tttaagatac ttgaattcta acaataataa
      421 cttgaatttt caatatatag ttcaactttt aatagcattt gttattattt atttcccttt
      481 gagtcaacta ttacaatttt tgacacctaa tattattgtt cgtagtatag gaggggtagt
      541 tgtttctata ctgctttcta tattatatat gagaggaagg acgaaatatg ttctacgtaa
      601 atagttatgt ttttgcttat aaaaaagaag gtataatgta tttgcgtggt cggagtatgc
      661 gggaaatagc tatagaacct caaatttcgc aagaatttat caacgatcta tttaatagtt
      721 gtaaggaact attagagata gaagaagtat taggtagtaa actaacattt gaactattaa
      781 atgaacaaat tttaatttcg gatgagatag atattgatag tagatattct agaactaaag
      841 gttactattc gttattttat aatgaagagt ataataaaat acagaataaa acagtattag
      901 tattaggagc cggagcctta ggatgttata tatctctaag tctaagtatg tatggagtga
      961 ggaaacttat tgtcgctgat tacgatataa tagaaccatc aaatttaaat aggcaaattc
     1021 tttatacaga gtcggatgtt ggtaaggaga agattaatgt tctttctcaa aaaatacaca
     1081 agtataattc agatgttcag gtagtaccta tttctattaa agtttcttca gtagaagaat
     1141 tagaaaacat tgttgcggaa tatgggagta tagattttat cgttaaagca attgatacgc
     1201 ccattgatat tataaaaatt gtcaatcaat ttgctgtatc gcataagata tcctacatat
     1261 caggagggtt taatggatgc tatcttatta ttgataatat atatatccct accatcggtt
     1321 cttgctttgc ttgtcggaat ataaacaaag atataaataa gtacacttta tctgataaga
     1381 caaagtggcc gactacacca gagatgcctg ctattttggg agggataatg actaatttaa
     1441 taattaaaat atttctggga tgttataatg aaatcctaat agataacgct tacgtttata
     1501 atatgagaaa tcatgctcta agtcaagaaa aatatgttct ggaaaacgga gaatgtccaa
     1561 tttgtaaaaa aaataataaa gtgaaagata acaatattag agcgaaaaca tttattcgtt
     1621 cagtttgttt ttgcttatta tcaggaggag tagctttttt atctgctatt gggcagttca
     1681 ctgttataga aacacaatta atagtattgt tcttgggtat tatttttgct atatattatg
     1741 cttactacaa taaaaatatt caaacatcat tggaaaatat agtatggctt ttttcatcgt
     1801 ttgagatttt atttttgctt gttaatttta gaacatttat tcagttacca gtggatattt
     1861 ttattagtat gataatattt ttaatgctgt ggata
//
LOCUS       DAVLHM010000099         1855 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLHM010000099 DAVLHM010000000
VERSION     DAVLHM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.099"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            16..88
                     /locus_tag="VXE45_002102"
     tRNA            16..88
                     /locus_tag="VXE45_002102"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49..51,aa:Asp,seq:gtc)
     gene            113..185
                     /locus_tag="VXE45_002103"
     tRNA            113..185
                     /locus_tag="VXE45_002103"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:146..148,aa:Lys,seq:ttt)
     gene            191..272
                     /locus_tag="VXE45_002104"
     tRNA            191..272
                     /locus_tag="VXE45_002104"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:225..227,aa:Leu,seq:tag)
     gene            291..363
                     /locus_tag="VXE45_002105"
     tRNA            291..363
                     /locus_tag="VXE45_002105"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:324..326,aa:Thr,seq:tgt)
     gene            386..457
                     /locus_tag="VXE45_002106"
     tRNA            386..457
                     /locus_tag="VXE45_002106"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Gly,seq:gcc)
     gene            465..550
                     /locus_tag="VXE45_002107"
     tRNA            465..550
                     /locus_tag="VXE45_002107"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:499..501,aa:Leu,seq:taa)
     gene            560..633
                     /locus_tag="VXE45_002108"
     tRNA            560..633
                     /locus_tag="VXE45_002108"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:594..596,aa:Arg,seq:acg)
     gene            649..722
                     /locus_tag="VXE45_002109"
     tRNA            649..722
                     /locus_tag="VXE45_002109"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:683..685,aa:Pro,seq:tgg)
     gene            728..801
                     /locus_tag="VXE45_002110"
     tRNA            728..801
                     /locus_tag="VXE45_002110"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:762..764,aa:Met,seq:cat)
     gene            815..888
                     /locus_tag="VXE45_002111"
     tRNA            815..888
                     /locus_tag="VXE45_002111"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:849..851,aa:Ile,seq:cat)
     gene            899..988
                     /locus_tag="VXE45_002112"
     tRNA            899..988
                     /locus_tag="VXE45_002112"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:935..937,aa:Ser,seq:tga)
     gene            999..1072
                     /locus_tag="VXE45_002113"
     tRNA            999..1072
                     /locus_tag="VXE45_002113"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1033..1035,aa:Met,seq:cat)
     gene            1076..1148
                     /locus_tag="VXE45_002114"
     tRNA            1076..1148
                     /locus_tag="VXE45_002114"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1109..1111,aa:Phe,seq:gaa)
     gene            1168..1238
                     /locus_tag="VXE45_002115"
     tRNA            1168..1238
                     /locus_tag="VXE45_002115"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1200..1202,aa:Gly,seq:tcc)
     gene            1274..1347
                     /locus_tag="VXE45_002116"
     tRNA            1274..1347
                     /locus_tag="VXE45_002116"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1308..1310,aa:Ile,seq:gat)
     gene            1354..1441
                     /locus_tag="VXE45_002117"
     tRNA            1354..1441
                     /locus_tag="VXE45_002117"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1388..1390,aa:Ser,seq:gct)
     gene            complement(1574..>1855)
                     /locus_tag="VXE45_002118"
     CDS             complement(1574..>1855)
                     /locus_tag="VXE45_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0790057.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          437 a          386 c          490 g          542 t
ORIGIN      
        1 ccgttaactc ccaaaggtcc cgtagtgtag cggttatcac gtcgccctgt cacggcgaag
       61 atcgcgggtt cgattcccgt cgggaccgtt taaggtaacg caagttattt tagactcgtt
      121 agctcagttg gtagagcaat tgacttttaa tcaatgggtc actggttcga gcccagtacg
      181 ggtcatatat gcgggtttgg cggaattggc agacgcacca gatttaggat ctggcgctta
      241 acggcgtggg ggttcaagtc ccttaacccg cattaagata taacaaatga gccggcttag
      301 ctcagttggt agagcatctg atttgtaatc agagggtcgc gtgttcaagt catgtagccg
      361 gcatttttag atagaagaaa acagtgcgaa cgtagttcag tggtagaaca ccaccttgcc
      421 aaggtggggg tcgcgggttc gaatcccgtc gttcgcttag agaggccggg gtggcggaac
      481 tggcagacgc acaggactta aaatcctgcg attggtaacg atcgtaccgg ttcgattccg
      541 gtcctcggca taatatggag cacccttagc tcaactggat agagtacctg actacgaatc
      601 aggcggttag aggttcgact cctctagggt gcatttttct atttaactcg ggaagtagct
      661 cagcttggta gagtacttgg tttgggacca aggtgtcgca ggttcgaatc ctgtcttccc
      721 gattcatggc ggtgtagctc agctggctag agcgtccggt tcatacccgg gaggtcgggg
      781 gttcgatccc cttcgccgct ataatgatct tgtcggacct ttagctcagc tggttagagc
      841 tctcggctca taaccgagtg gtcgtaggtt caagtcctac aaggtccatt tgaatattgg
      901 aggattaccc aagtccggct gaagggaacg gtcttgaaaa ccgtcaggcg tgtaaaagcg
      961 tgcgtgggtt cgaatcccac atcctccttt tatattaacg cgggatggag cagctcggta
     1021 gctcgtcggg ctcataaccc gaaggtcgta ggttcaaatc ctgctcccgc aataaggctc
     1081 ggtagctcag ttggtagagc aatggattga agctccatgt gtcggcggtt cgattccgtc
     1141 tcgcgccatt ttattgatag tatttatgcg ggtgtagttt agtggtaaaa ctacagcctt
     1201 ccaagctgtt gtcgcgagtt cgattctcgt cacccgcttt gaactttgtt caaattacca
     1261 agttttttaa cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg
     1321 tcggtggttc gagtccactc gtgcccatta attggagaat tactcaagag gctgaagagg
     1381 acggtttgct aaatcgttag gtcgggtaac tggcgcaagg gttcgaatcc cttattctcc
     1441 gttttaatga gagtttgtaa ctctcttttt tatttttaga gacaataaag cttcagatcc
     1501 gtaaaactta attgaattac taatctgaag ttatttttag gctctttgtc aactgtagtg
     1561 ggttgaaaaa aagctaagct cgagaaagga caaattttgt cctttctttt ttgatgttca
     1621 aagcgataaa aatccttttt ttgaagtttt caaagttccg aaatccaaag gcgtttcgtt
     1681 tgataagttt gatgagatta tttgtcgctt ccagtttggc gttagaatag tgtagttgaa
     1741 gggcgttgac aatcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag
     1801 gatgaacctg cttcagattg tcctcaataa gcccgaaaaa tttctctggt tcctt
//
LOCUS       DAVLHM010000100         1811 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLHM010000100 DAVLHM010000000
VERSION     DAVLHM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.100"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            4..77
                     /locus_tag="VXE45_002119"
     tRNA            4..77
                     /locus_tag="VXE45_002119"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38..40,aa:Asn,seq:gtt)
     gene            185..1031
                     /locus_tag="VXE45_002120"
     CDS             join(185..504,503..1031)
                     /locus_tag="VXE45_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0790058.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLKNYLTDNPDAYLTEIASEFGCHPTTIHYALKAMGYTR
                     KKEPHTYYEQDPEKVALFLKNFNSLKHLAPVYIDETGFDTYFYREYGRSLKGQLIRGK
                     VSGRRYQRISLVAGLTNGELIAPMTYEEMVTSDFFEAWFQKFLLPTLTTPSVIIMDNA
                     RFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALF
                     SCSCFN"
     gene            complement(1066..1811)
                     /locus_tag="VXE45_002121"
                     /pseudo
     CDS             complement(1066..1811)
                     /locus_tag="VXE45_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          577 a          300 c          365 g          569 t
ORIGIN      
        1 taatccgcca tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc
       61 gagtcctact ggcggagtaa ttgagttaag aggtttagac ctcttttttg ttatgtaata
      121 ataatctatt ttgtgttata gtaaaatgaa ccaaaaatag tacacaatgt ggtataatct
      181 ttttatggca tattcaatag attttcgtaa aaaagttctc tcttattgtg agcgaacagg
      241 tagtataaca gaagcgtcac acgttttcca aatctcacgt aataccattt atggctggtt
      301 aaagctaaaa gagaaaacag gagagctaaa ccaccaagta aaaggaacaa aaccaagaaa
      361 ggttgataga gatagactta aaaactatct tactgacaat ccagacgctt atttgactga
      421 aatagcttct gaatttggct gtcatccaac taccatccac tatgcgctca aagctatggg
      481 ctacactcga aaaaaagaac cacacctact atgaacaaga cccagaaaaa gtagccttat
      541 ttcttaaaaa ttttaatagt ttaaagcacc tagcacctgt ttatattgat gaaacaggat
      601 tcgatactta tttttatcga gaatatggtc gctcattaaa aggtcagtta ataagaggta
      661 aagtatctgg aagaagatat cagaggattt ctttggttgc aggtctaaca aatggtgagt
      721 taatcgctcc aatgacttac gaagagatgg tgacgagcga cttttttgaa gcttggtttc
      781 agaagtttct cttaccaaca ttaaccacac catcggttat tattatggat aatgcaagat
      841 tccatagaat gggtaagtta gaacttttat gcgaggagtt tgggcataaa cttttacctc
      901 ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggcttat atcaaaaaga
      961 acctcaaaaa ggtattacca agttgcaata ccttttacga ggctcttttc tcttgttctt
     1021 gtttcaattg actatattag aggcgagaca tttttcggtt ctttgtcaac tgtagtgggt
     1081 tgaagaaagc gaagatctag aaaggacaaa tttcgtcctt tcttttttga agttttcaaa
     1141 gttcctaaaa ccaaaggcat tgtgcttgat aagtttgatg agattattgg tggcttccag
     1201 tttggcgttg gaataaggta attgaagggc gttgacgatt ttctctttat ctttgaggaa
     1261 ggttttaaac agagtctgaa aaagaggtgg aaaagcaaga gctgatagag attatagctg
     1321 atagagatta tagtggtgtt tcaagtcttc gaatagctca aaagtttatc tagaatttct
     1381 ttattagtca agtgcatacg aaaagtaggg cgataaaatc gtttatcact cagtttctga
     1441 ctatcttgtt gaatgagctc cagtagcgct tgatagcctt gtattcatgg gatttcggat
     1501 gatggcttgt gttctgctct caagaacagt tatgatattg agcttatcaa agtcctgagc
     1561 aataaagctc atctctatct cccgattgaa acagtcactc cccagactgt ttcaacgtcc
     1621 taggacataa tctcaggaag acgcgaaaaa tcatgctcaa agtgaaaatc attgatcttg
     1681 cgaatgacag ttgaagttga aatagacaac tgatgatcaa tgtcggtcat agaaatcttt
     1741 tcaattaact tttgagcaat cttttggttg ataatacgag ggatttggtg attcttcttg
     1801 acgatagaag t
//
LOCUS       DAVLHM010000101         1517 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLHM010000101 DAVLHM010000000
VERSION     DAVLHM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.101"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            45..392
                     /locus_tag="VXE45_002122"
     CDS             45..392
                     /locus_tag="VXE45_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0790059.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(509..1468)
                     /locus_tag="VXE45_002123"
                     /pseudo
     CDS             complement(509..1468)
                     /locus_tag="VXE45_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          455 a          291 c          281 g          490 t
ORIGIN      
        1 tttaaaagat cggagcaatc cggtcttttt atggaggaga gtaaatgaat ttaaatcaat
       61 tagatattat cgtttcaaat gttccccaag tctgtgctga cttggagcat atcttggata
      121 aaaaggcaga ttatgctgat gatggttttg ctcagtttac gattggtagt cactgcctta
      181 tgttgtcaca aaatcatttg gttcctttgg aaaactttca gtcaggaatc attattcata
      241 tcgagattga ggatgtagac cagaactaca aacggttgaa cgagcttggt ataaaggttt
      301 tacacggacc aactgtaacc gattggggaa cagagtcctt attagttcaa ggacctgctg
      361 gtctagtgct tgatttttat cgtatgaaat aggtcgcgta gtcatttgac gttaacctta
      421 gctattttta aaatagaaat tgagaatatg aactattgaa agatcggagc aatccggtct
      481 ttttatataa agaaattgca tataatactc atctgctttc aaaaagcatt ctagtccatc
      541 tccgattaac gatggacttt atcacctcct tctccaatcc ttgtatgaca tcttggagtt
      601 gattcatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt ttacgaatct
      661 ctttccacac ttgttcaatg gggttcatct ctggtgtgta tggaggaata aatgcaaagc
      721 caatattagt cggaatcttt aaggtacttg atttatgcca tatagcattg tccataacga
      781 gtaaaaaata atcatatgga taagcttgtg aaagctcttc taaaaagacg ttcatccact
      841 cagtattaca tccaccagct cttaagaaaa atgattcgcc tgtataggca tcaacagctc
      901 cataacaata gcgaaattct cgtatatagt gactatggat atgtggacct actcctattg
      961 gagaccaaca agatcccagt ttactgattc taccgaaacc agcctcatct tggtacatca
     1021 agcgaacctt acgaaaacgt ctactggttt taaatcgctt tcttttcttc ttgaattgag
     1081 attttatttt tagacgcgac aatggtttga gcgtctgctt tcttaggatg ttctggacgt
     1141 ggcgtaatat ttcgccaacc atggcgcttc aacagttgat agaaggcatc acgtgtgtag
     1201 gaacgaccta actccttttt ataagcctga aataaggcat caattgtaac aaattctcct
     1261 gcctctgtag ccttcaaatg acgggcaaga aaggctttct cttcctcaac tgtcatatat
     1321 gcatggttac gaccaccacg tgtttcttga aggagagagt cgagtccgaa ctcctcatat
     1381 tttttacatt ttgctaaatc gttgtttgat tacagtctaa aagctctata atctctttat
     1441 aagatttgcc catcagacga aatataatag attgaaacta gaatagtaca cctctacttc
     1501 taaaacattg ttagaaa
//
LOCUS       DAVLHM010000102         1498 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLHM010000102 DAVLHM010000000
VERSION     DAVLHM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.102"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            48..1394
                     /gene="gdhA"
                     /locus_tag="VXE45_002124"
     CDS             48..1394
                     /gene="gdhA"
                     /locus_tag="VXE45_002124"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0790060.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
BASE COUNT          454 a          304 c          320 g          420 t
ORIGIN      
        1 gctataatgt cttatgtaat aaaatatgac aataaaagga gaacgatatg acatctgcta
       61 aagaatatat ccaaagcgtg tttgaaactg taaaagctcg taacgggcac gaggctgaat
      121 tcctccaagc tgttgaagaa tttttcaaca ctttggaacc tgtatttgaa aaacaccctg
      181 agtatatcga agaaaatatc ttggcacgta ttactgagcc tgagcgcgtg atttctttcc
      241 gtgttccttg ggttgaccgt gatggaaaag ttcaagtaaa ccgcggctac cgtgttcaat
      301 tcaactcagc tgttggacca tacaaaggtg gacttcgttt ccacccaact gtaaaccaag
      361 ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa tgtcttgact ggacttccta
      421 tcggtggagg taaaggtgga tcagacttcg atcctaaagg taaaacagat gctgaagtga
      481 tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca catcggacca tcacttgacg
      541 tacctgctgg tgatatcggt gttggtggac gtgaaattgg ttacctttac ggtcaataca
      601 aacgtcttaa ccaatttgat gctggtgtct tgactggtaa acctcttgga tttggtggta
      661 gcttgattcg tccagaagca actggttacg gtttggttta ctatactgaa gaaatgctca
      721 aagctaacgg taacagcttt gctggtaaga aagtcgttat ttcaggttct ggtaacgttg
      781 ctcaatacgc tcttcaaaaa gcaaccgaac ttggtgcaac agttatctct gtttctgact
      841 caaacggcta tgttatcgat gaaaacggta tcgacttcga tcttttggtt gatgttaaag
      901 aaaaacgtcg cgctcgtttg actgagtatg cagctgagaa agcaactgct acttatcatg
      961 aaggttctgt atggacttac gctggaaact atgacattgc gcttccatgt gctactcaaa
     1021 acgaaatcaa cggtgaagca gctaaacgtt tggttgctca aggcgttatc tgtgtatctg
     1081 aaggtgccaa catgccaagc aaccttgatg ccatcaaagt ttacaaagaa aatggtatct
     1141 tctacggacc tgccaaagct gccaacgctg gtggtgtagc cgtttcagcc cttgaaatga
     1201 gccaaaacag ccttcgcctc tcatggactc gtgaagaagt tgatggacgt ctcaaagaca
     1261 tcatgaccaa catctttaac acagctaaaa caacttcaga aacatatggt cttgataaag
     1321 actaccttgc aggagctaac attgctgcct ttgaaaatgt agcaaacgct atgattgcac
     1381 aaggcgtggt ataaaaaaaa attacggaaa ctgactaccc agacgggtag ccagtttttt
     1441 caattcctaa aatttaagat tctaataccc tttatgcaaa aatatagaat tctacctt
//
LOCUS       DAVLHM010000103         1341 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLHM010000103 DAVLHM010000000
VERSION     DAVLHM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.103"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>1341)
                     /gene="lanM"
                     /locus_tag="VXE45_002125"
     CDS             complement(<1..>1341)
                     /gene="lanM"
                     /locus_tag="VXE45_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEV0790061.1"
                     /translation="FSSLVFYLEDLIYPWIVKPLVLEINSLREKGLLEGESEQQRYKY
                     FITLFDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEELGLRG
                     KLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIAEYIRKVDEKIRI
                     RIPRTIAYSDHSYEEFIDYLPLEQKKNLPEYYYNFGVLLAFIYLFNGSDIHFENLISY
                     GDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGLDVEMSAL
                     TGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEFDKYIKDFKKGFR
                     DFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLYHPDFYEEMLDRE
                     KALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFGNHFISLHQ"
BASE COUNT          464 a          249 c          154 g          474 t
ORIGIN      
        1 attgatgtag ggaaataaaa tgatttccaa aatcatcgta gatttcattg atatttgtat
       61 ctgtataaaa aatcggaata tctaataacc tcatttgttc acattcgctt gctacaatac
      121 cttgattaga aaacttattg ctccagagat tttccaatgc tttttctcta tctaacattt
      181 cttcataaaa atcaggatga tataaaaaag atagtactga agcatagcta tttgtgtctc
      241 taaaaagtac ccttgtcttt aaaccataca agtttgcttt taatagcatt ttaaattctt
      301 ctgttttatt taactcttca aatatcagat aaaaatccct aaaacctttt ttgaaatctt
      361 ttatatactt atcaaattct atatcaccat cccgaacagg caggtttttc ccaccttcaa
      421 aatcaatttt cccaatatca aactttacct tatcagtatt taaattaatt aaaacttgac
      481 cattaaaagc atccttctta aaatttcctg taagagcact catctcaaca tcaagaccat
      541 cctccctttt tactccctct gttggaagaa gcaaagttcg agtcaccctg tgaaacaggg
      601 tatccagcaa actctgacca gttttatcat caaatagagg ttgctgtaac attgtttcaa
      661 agtctattat tacaggcata tctccatagg aaattaaatt ttcaaaatgt atatcactcc
      721 cattaaataa atatataaat gctaaaagca caccaaaatt ataataatat tcaggtaaat
      781 ttttcttttg ctctagaggt agataatcaa taaattcttc atagctgtga tccgaataag
      841 caatagttcg aggtattctt atcctaattt tttcatcaac ctttcggata tactcagcaa
      901 tagtatttag tgagttattg attattaaat ttttaggctt gtaaacaatt ttcgcgtcat
      961 caaagaagag tatcaaaaca gtttttcctt ggctgtgtgt atcacccttt ccaaatttta
     1021 tatcatttaa tttccccctt agccctaatt cttcttctag cacactaaaa tcattttcta
     1081 aatttgataa aatttctata aaataagtat agaaccgaag acaagactcc gatatttgcc
     1141 tcagtaaaac gggatatttg ttataaaaat ttaatatatt ctcttccttg tcaaacaatg
     1201 ttataaaata tttgtaccgt tgctgctccg attccccttc aagtaaacct ttttcacgca
     1261 atgaatttat ctctaaaacc aaaggtttaa caatccaagg atagattaaa tcttctaaat
     1321 aaaatactag agaggaaaaa a
//
LOCUS       DAVLHM010000104         1316 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLHM010000104 DAVLHM010000000
VERSION     DAVLHM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.104"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>1316)
                     /locus_tag="VXE45_002126"
     CDS             complement(<1..>1316)
                     /locus_tag="VXE45_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0790062.1"
                     /translation="KKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIY
                     NDKIVKIADQSLDDYIVIKFLINKKISILEILHELYPVNDQRVVQILNQCSNFIRKES
                     DLEGVSDAVKSYYYNESNFESDELKEKFLIQFGVLLPLEAISHVKNKIDNIESQVYTK
                     TNFINQKDKKGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKISEVYSILEAN
                     YGLVTEREYIDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIERTETHEEKF
                     TFGRYKVPDSEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRKILTYSESHR
                     NTIFGDLRNIRKLFFNDIKNLSMIGEKIVYALHKAEVKENLPIVFDDYIISDRQKIYN
                     NLTNPNHAWFYDASEIKLQQIANSYSNVWLKIFNFANQFKHSLFMN"
BASE COUNT          437 a          206 c          143 g          530 t
ORIGIN      
        1 attcataaat aagctatgtt tgaattgatt tgcaaaatta aaaattttaa gccaaacatt
       61 tgaatagcta tttgcaattt gttgtagttt aatttcagaa gcatcataaa accaagcatg
      121 gttaggattt gttaaattat tatatatttt ttgtctgtca gaaattatat aatcatcaaa
      181 aacaatcggt aaattttctt tcacttcggc tttatgcaaa gcataaacta ttttttctcc
      241 aatcatagat aagtttttaa tgtcattaaa aaataatttc ctaatatttc tcaaatctcc
      301 aaagatagta ttacgatgac tttctgaata ggtcaaaatt tttcttctgt aatcatatag
      361 cattttctca atataaaatc tagtttcaca actccctata ttatacaaat tcgctaaaag
      421 ttttagtata cttctatgat actgttttaa tttttcacta tccgggactt tatagcgccc
      481 aaaagtaaat ttctcttcat gagtctctgt tctttcgatt tcaattttaa gaaactgctt
      541 caaaattgtc acgattaatt cttggttata acttttcgtc aaatcaagat tagcaagttc
      601 agaaatggta ttttcagcta aggtataatc aatatattct ctttctgtaa ccaacccgta
      661 gtttgcttca agaatactat aaacctcaga aattttatta ggatttttat caaagtactt
      721 taacaataat tggagaattt gactacaata ttttgtccgt gtagttacaa atacaatatt
      781 taaaactgaa tcctcaatag atcccttttt atccttctga ttaataaaat tagtctttgt
      841 ataaacctga gactctatat tatcaatttt atttttaacg tgtgaaattg cttctaaagg
      901 aagtaatact ccaaattgta ttaaaaactt ttctttaagt tcatcacttt caaaattact
      961 ttcattgtaa taatatgatt taactgcatc agaaacgcct tctaaatcac tctctttcct
     1021 aataaaattg gaacattgat ttagtatttg aacaactctt tggtcgttta ctggatataa
     1081 ctcatgtaaa atttctaaaa ttgatatttt cttgttaatt aaaaacttga taactatata
     1141 atcatctaat gattgatctg ctatctttac aattttgtcg ttataaatat tacacaactc
     1201 tctttcatga agcttctcca ctgcactctt aaagtcagta tttgttatgt cagttatttt
     1261 tagtaattta ttgaattcct ggttctcttc taaactttcc agtctaatct ttttta
//
LOCUS       DAVLHM010000105         1301 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLHM010000105 DAVLHM010000000
VERSION     DAVLHM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.105"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..213)
                     /locus_tag="VXE45_002127"
     CDS             complement(<1..213)
                     /locus_tag="VXE45_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0790063.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRHGHGNRNRKPKHAIPDEIKER"
     gene            377..529
                     /gene="rpmG"
                     /locus_tag="VXE45_002128"
     CDS             377..529
                     /gene="rpmG"
                     /locus_tag="VXE45_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0790064.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            539..715
                     /gene="secE"
                     /locus_tag="VXE45_002129"
     CDS             539..715
                     /gene="secE"
                     /locus_tag="VXE45_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0790065.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            770..>1301
                     /gene="nusG"
                     /locus_tag="VXE45_002130"
     CDS             770..>1301
                     /gene="nusG"
                     /locus_tag="VXE45_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0790066.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT          410 a          204 c          258 g          429 t
ORIGIN      
        1 acgttctttg atttcatcag ggattgcatg ttttggtttt cgatttctgt ttccgtgtcc
       61 gtgtctgaag gcttcttttc ctttctgttg ataggctagt aacagacgat tgatttgtct
      121 ttcagaaaga ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc
      181 ttttatcaca agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact
      241 attctaccaa atgggacatt ttcacgttcg atttactaaa gacattatca cattcgaatc
      301 acaatagtca atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg
      361 ataagatgga ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc
      421 gagaaactat tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa
      481 attttgtaag cattgtggca agtacactac acacagagaa acgagatagg agagagcgat
      541 gcgttttatt ggagatattt ttagacttct taaagacaca acgtggccaa ctcgcaagga
      601 aagctggaga gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta
      661 catttttgac cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat
      721 tagtggagtt aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt
      781 tgataaaggg tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa
      841 tctattacaa cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc
      901 aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt
      961 tccaggttat gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa
     1021 cacaccaaat gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt
     1081 attggaacaa gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga
     1141 tttcgatgtt gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac
     1201 tggtaagatt acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa
     1261 tgacacagtt gcagaagtaa acctaaacca aatcgcagaa t
//
LOCUS       DAVLHM010000106         1288 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLHM010000106 DAVLHM010000000
VERSION     DAVLHM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.106"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            466..>1288
                     /locus_tag="VXE45_002131"
     CDS             466..>1288
                     /locus_tag="VXE45_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0790067.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVD"
BASE COUNT          383 a          218 c          277 g          410 t
ORIGIN      
        1 ttttttcttt ttaaatattg attgtttcta aaagttctag taatattgct atttctcatt
       61 tttccaaata tgttattcaa cttattagct acgtctctat tcatatttgg gtataaaaca
      121 aaaaatcaat tctaacagtt ttatatcaga ataataaata aaaaagcgat attctagact
      181 gtatcaatcc ttttccatta taggagcaac agagtgggag tagtcatcta aggactaatt
      241 tatatatttt tacgagtcag tatcttggga tactggtttt tactttttta gactttttga
      301 ctacttgtta aaactggggt aattttcgac tgtttaatag ttattatgca aagtctaaaa
      361 gattagaatt gtcaaaacaa tccgtctagg cttgatttta tcctttattt actataaaat
      421 gagaaggaaa aatgtcaaac ttttatattg caaataggag aaatcatgac aaaaacatta
      481 aaacgtcctg aggttttatc acctgcaggg actttagaga agctaaaggt agctgttcag
      541 tatggagcag atgctgtctt tatcggtggt caggcctatg gtcttcgtag ccgtgcggga
      601 aactttactt tcgaacagat ggaagaaggc gtgcagtttg cgaccaagta tggtgccaag
      661 gtctatgtag cggctaatat ggttatgcac gaaggaaatg aagctggtgc tggtgagtgg
      721 ttccgtaaac tgcgtgatat cgggattgca gcagttatcg tatctgaccc agccttgatt
      781 atgattgcag cgactgaagc accaggcctt gaaatccacc tttctaccca agccagtgcc
      841 actaactatg aaacccttga gttctggaaa gagctaggct tgactcgtgt cgttttagcg
      901 cgtgaggttt caatggaaga attagctgaa atccgcaaac gtacagatgt tgaaattgaa
      961 gcctttgtcc atggagctat gtgtatttca tactctggac gttgtactct ttcaaaccac
     1021 atgagtatgc gtgatgccaa ccgtggtgga tgttctcagt catgccgttg gaaatacgac
     1081 ctttacgata tgccatttgg gaaagaacgt aagagtttgc agggtgagat tccagaagaa
     1141 ttttcaatgt cagccgttga catgtctatg attgaccata ttccagatat gattgaaaat
     1201 ggtgtggaca gtctaaaaat cgaaggacgt atgaagtcta ttcactacgt atcaacagta
     1261 accaactgct acaaggcggc tgtggatg
//
LOCUS       DAVLHM010000107         1271 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLHM010000107 DAVLHM010000000
VERSION     DAVLHM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.107"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(766..1263)
                     /locus_tag="VXE45_002132"
     CDS             complement(766..1263)
                     /locus_tag="VXE45_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEV0790068.1"
                     /translation="MTEFPIEFFNKSDAGFQHMIKTYDQMINQKQSKLGYKKFFKLLL
                     SHPKDESLLFHCSMGKDRTGIASLFLLYILGVDMNDIFHDYLLSNKYLINVRKENIEY
                     VNNHSGNVILMHNLLSLSSAKEEYINRVLNVLDKEYGGILRYINTELGISSQEIEELK
                     DRYLF"
BASE COUNT          424 a          221 c          153 g          473 t
ORIGIN      
        1 aataactgaa gatattgaca ggaagatatt aaattcctca ttactatcct ttactatgca
       61 gtataatttt aatatcattt acctacttcc aagatgctga aaaatactaa gtcacactat
      121 tatgatgtta ttatttccat ttttatttta acagatgagt caattctttc aactaccccc
      181 tcccttataa ctatattcat gaagtattct tgataataaa cctcatttaa cttctcaaag
      241 tagtcagctt ctgcaactgc tattatctca taacagattg atttggtttc aataaatgga
      301 agctagaagc cttgtcagct accctgcaca gttggtgttt tttcattttt ctcttcaaaa
      361 aaattggtcg gaagttataa taaaaaggtg atgtgtttgt ggtgagttga attaagagac
      421 aaactcactt tgtcttaact tttaaattgc ctaacaaaaa tacggagatt attctctaag
      481 ctttaactgc aacattatgt ctctacaacc aacgataagt ccagaaatct acccaaataa
      541 ccaaacaacc tacatttgtt gaactttgat gacaagtagg aaattttaca tttgataaac
      601 actattttgt acgcattttg cacataattt aacgtgcttt ccatcaattt agttaaggac
      661 ttacatagaa aacaatccgt ttttgcttat gttaaattag tagaattaga caaaaacaaa
      721 accgccgttc gcactgttat atattcattt ttagtactta ctattctaaa aaagatatct
      781 atctttcaat tcctcaattt cttgactact tattcctagt tctgtattaa tatatctaag
      841 tattcctcca tattctttat caaggacatt caatactcga ttaatatatt cttcttttgc
      901 tgaactgagt gaaagtaaat tatgcatcaa tattacattc ccactatggt tatttacata
      961 ttcaatattt tcttttctca catttattaa atacttgtta gatagtaagt aatcatgaaa
     1021 aatatcgttc atatctactc ccaatatata aagcaagaac aagctagcta ttcctgttcg
     1081 atccttcccc attgaacaat gaaacaaaag agattcatct tttggatgac ttagtaataa
     1141 tttaaagaat ttcttgtaac caagtttact ctgtttttga ttgatcattt gatcataagt
     1201 ttttatcata tgttgaaaac ctgcatctga tttgttaaaa aattctattg ggaattctgt
     1261 caactctgaa t
//
LOCUS       DAVLHM010000108         1267 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLHM010000108 DAVLHM010000000
VERSION     DAVLHM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.108"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..265)
                     /locus_tag="VXE45_002133"
                     /pseudo
     CDS             complement(1..265)
                     /locus_tag="VXE45_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(500..811)
                     /locus_tag="VXE45_002134"
     CDS             complement(500..811)
                     /locus_tag="VXE45_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790069.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCSFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(826..1233)
                     /locus_tag="VXE45_002135"
     CDS             complement(826..1233)
                     /locus_tag="VXE45_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEV0790070.1"
                     /translation="MWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVVSYD
                     DAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIK
                     VPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT          382 a          262 c          218 g          405 t
ORIGIN      
        1 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
       61 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaatg tggtcaatca
      121 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
      181 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
      241 caccacggtt ggcatcacgc atactctaga cgcaattcta atcttttaga ctttgcataa
      301 taactgttaa acagttgaaa attaacccag ttttaacaag tagtcaaaat accagataaa
      361 ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca atcttgatat
      421 tatgcgtttt attgtgggaa gatttacttc attttctctt ggaattgagt tttctcctac
      481 ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg caacctggat
      541 taaagcgaga aaaacaaaag gagcaactta aactttcttt atattgctta tatgttagta
      601 gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag ggatacggct
      661 caaaagggtg attttctaat gaatcatgac accgataaca agcatagtac tttttacaat
      721 catagcattg taaagcaata atatccaact tgctatggta atgaatgcat cttgtttgct
      781 tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag cacgaactgt
      841 gacgctggtt ccatcttcct tataaaaatt gatgagtcct tcttttaatg cacgaaccat
      901 gtctcctgat tgaacgggtt gtgggacttt aatagtcaat agttccattg gatttggagc
      961 gcggtcgatt ttattgcctt tggcatcatg caaatcttca atataggttt caaaatgacg
     1021 gaaacctgga ccataaaact caacttggtc cccttcgtta atgacgtttc gttgacgaat
     1081 ggttgctgtt tgtgccgcat catcataaga aaccacttca gcgacaaact tgtactcagg
     1141 aattttacgg cgagcaccaa acaactgctc attttcagat ggtataccgt agtagaaacc
     1201 tgttgccaat tcacgttggg caaccttcca catctcgtcc accaagtctt gtttgatagc
     1261 ttcaaac
//
LOCUS       DAVLHM010000109          889 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLHM010000109 DAVLHM010000000
VERSION     DAVLHM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.110"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..669)
                     /locus_tag="VXE45_002136"
     CDS             complement(<1..669)
                     /locus_tag="VXE45_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="HEV0790071.1"
                     /translation="MLHPIFIIRRSWDGIFHLSEWKRNEEFDFFNKMDVPYLSMSSRI
                     EVTQAINFHKKHSISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTS
                     EDKLNFSSFTMGDNLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVST
                     PMNLSKIDTVPRITWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKIN
                     EYFQK"
     gene            complement(728..>889)
                     /locus_tag="VXE45_002137"
     CDS             complement(728..>889)
                     /locus_tag="VXE45_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790072.1"
                     /translation="TPVYSLGSGSRIVMYYNGGGDNYIGSGTRLAMAPQFGNHVRIHT
                     SGSWSPDSY"
BASE COUNT          300 a          172 c          121 g          296 t
ORIGIN      
        1 tttttgaaaa tattcattta ttttatttac aaacctttgc aataacacaa aaaaattaga
       61 tacgtgtaat ccatctccca ttccatgatt aatttgtaaa ttcactgtac aaaaatatct
      121 ttggttctct tgaataactt ttccccacgt tattcgagga actgtatcaa tttttgaaag
      181 attcatagga gtgcttacat gtaaaaaatc aatccatgga acacaagaaa gataagcaat
      241 gttattcttg tcaatatttg gtttttgccc ttcttctgcc ttctgtttat ttatgttgaa
      301 cgcagaaaca aattcaatta aattatctcc catcgtaaat gaagaaaaat taagcttatc
      361 ttccgatgta agggtagtga aagaacaacc tctttgattg tattgccaga caatctttcc
      421 gtcggtatcc attagtaatt ctggaataga atttattgca ctcataacac accacgatat
      481 tatggcataa agtgatatcg aatgtttttt atgaaaattg atagcctgcg ttacttctat
      541 tcgtgaactc atagataaat aaggaacatc cattttattg aaaaagtcaa attcttcatt
      601 ccttttccac tctgataaat gaaaaattcc atcccaactc ctccttataa taaaaatagg
      661 gtgtagcatt cttttttcat gctacaccca caatcaacca tctttaaggc ttactctgac
      721 aagtaagtta ataagaatct ggactccaag aacctgaagt atgaattctt acatgatttc
      781 caaattgtgg cgccatagct aatctagtac cagaaccaat ataattgtca ccacctccat
      841 tatagtacat gacaatccta gagccagacc ccaatgaata taccggggt
//
LOCUS       DAVLHM010000110          877 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLHM010000110 DAVLHM010000000
VERSION     DAVLHM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.111"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            97..552
                     /locus_tag="VXE45_002138"
     CDS             97..552
                     /locus_tag="VXE45_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790073.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            549..695
                     /locus_tag="VXE45_002139"
     CDS             549..695
                     /locus_tag="VXE45_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790074.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
BASE COUNT          322 a          129 c          161 g          265 t
ORIGIN      
        1 tttttatgtg cagagttata gtggcttgat gctgggaaag tacactgtga ctgctaaaac
       61 attcctagaa gttgctttga tttacctaat ctatttatgc aaattttatg ttattttact
      121 ataacagttg ttgctaagcc aaataatagt ggggaagttc atttagacgt aagcattgaa
      181 gataatcagg gaggtagtgg gcataatttc agttctgttt caagtagctc acaaacagct
      241 aaatatgaag aaactggtta taataacaat tcatcattat atataacgat tgataaaacg
      301 tctgatgcaa cagctctttt gaaattaaag ttgaataatg ttgataatca acctgctact
      361 gaagttccta gttcaggaat tactgtaaaa ttaaatgcta aagataatgc tggaaactgg
      421 acaagtgctt cgaataaaaa agaaataaca gtaaaaattg tttctgctaa accgacatat
      481 ccagacaaaa tcttagtgaa aaatcctgat aatataaaag atacagaaaa aatgccatta
      541 ttgaaaaatt gaaagaggca aataaaaatc atccagcagg agctccaacc tttgctaaag
      601 gtgaaggaga gcatgcaaat gatattgtag caacttattc agatggtaca acttattatg
      661 taccgttaaa tgatgtgaca aaatatgcga ggtagtggct gtaccactca cttattcacc
      721 tccccgtgat ttgtagtagt gataggcttt ctcactatta ttataaaaca aaataaagat
      781 cacaacactt tttcattctg tgttgtgcct tgagtgaaac gaaaggaatg aattataaat
      841 atgaaaagta tagtcactag catagatgag cgcttgc
//
LOCUS       DAVLHM010000111          838 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLHM010000111 DAVLHM010000000
VERSION     DAVLHM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.112"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..792
                     /locus_tag="VXE45_002140"
     CDS             <1..792
                     /locus_tag="VXE45_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY-like element IS1202 family transposase"
                     /protein_id="HEV0790075.1"
                     /translation="FDKQETLNAYYHVLEQILANHGIPLQMKTDKRTVFTYQASNSKK
                     MEDDTYTQFGYACHQLGILLETTSIPQAKGRVERLNQTLQSRLPIELERNKIHTLEEA
                     NTFLLSYIQTFNEQFGNKTKLSVFEEAPNPSERNLILARLAERVVDSGHHIRFQNRCY
                     IPTEQGKEVYFIRKTKALVLKAFDGDIYLNIADKIYHTKELLDHELYSKNFEQEPEQK
                     KERRKYIPPQTHPWKLTSFKQYLHKNKKDYEEFTSEEIHSPQLQV"
BASE COUNT          299 a          200 c          136 g          203 t
ORIGIN      
        1 tttgacaaac aagagacctt gaatgcctac taccatgtcc tcgaacaaat cttagccaat
       61 cacggcattc cccttcaaat gaaaactgat aagagaacgg tctttaccta tcaagcatcc
      121 aactctaaga aaatggagga cgacacctat acacaatttg gatacgcctg tcaccaacta
      181 gggattctcc ttgagaccac ctctatccct caagctaaag ggagggtcga aagactcaat
      241 cagacactac aatcacgcct gcctatcgaa ctggaacgaa acaagattca tacattggaa
      301 gaagccaata ctttccttct ttcctacatc caaaccttta atgaacagtt tggaaataag
      361 acaaaactct ctgtttttga ggaggctcct aacccctctg aacggaatct cattctagct
      421 agactggcgg agagagtcgt cgatagtgga caccatatcc gattccaaaa ccgttgctat
      481 attcctaccg aacaaggaaa agaagtctat ttcatcagaa agacgaaagc attagttcta
      541 aaagcatttg atggtgacat ctacctcaat atcgctgaca aaatctatca cacaaaggag
      601 ctactagatc atgaactcta ttcgaaaaac tttgaacaag aaccagaaca aaaaaaagaa
      661 agacgcaagt atatccctcc acaaacccat ccgtggaaac tcacatcttt caaacaatac
      721 cttcataaaa acaaaaagga ttatgaagag tttactagtg aggagattca ttctcctcaa
      781 ctacaagtat aatctatttt tcgctaaatg ggaagctttt ccttaaagga agtcactc
//
LOCUS       DAVLHM010000112          797 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLHM010000112 DAVLHM010000000
VERSION     DAVLHM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.113"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            306..530
                     /gene="pneA1"
                     /locus_tag="VXE45_002141"
     CDS             306..530
                     /gene="pneA1"
                     /locus_tag="VXE45_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEV0790076.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            537..725
                     /gene="pneA2"
                     /locus_tag="VXE45_002142"
     CDS             537..725
                     /gene="pneA2"
                     /locus_tag="VXE45_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEV0790077.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
BASE COUNT          280 a          101 c          161 g          255 t
ORIGIN      
        1 aaaaacaagg aaaaagaaag gggtttcatt gcatgagaaa aaaacgtgga attaaaaaat
       61 tagttacatt tgcattgcta ggtgttttta tgtttagtaa tacaattcct taccaacagt
      121 ttattcagaa gaataaacaa ttggagattc gagtgcaatc gcaaaagaag tccaatggtc
      181 ttgatgttgg gaaggcggat taaaacccga tattttgcac gagaatgaga gaattataat
      241 ttatctgaaa aaacgaaaaa tatagagcaa cttatttaac tttttataag gaggagttat
      301 tacttatgac caactttaat tcaaacgaaa aattttgtgg aaaaagttta aaatcattgt
      361 ctgctgatga aatgagttta atttatggtg catctgatgg tgcagagcca cgttggacgc
      421 ctactcctat tattttgaaa tcagctgcag ctagctcgaa agtatgcatt agtgcagctg
      481 tttctggtat tggggggcta gttagctaca ataatgattg tttggggtaa attaaaatga
      541 aaaatgattt tgtaatcgga aagagtttga aagaattatc tcttgaagaa atgcaattgg
      601 tttatggtgg cacagatggt gctgacccta gatcaacaat tatatgttct gctacattaa
      661 gttttattgc atcatatttg gggtcagctc agactcgttg tggcaaagac aacaagaaaa
      721 aataaaatat tcaattttaa aaataaaagt tgctctttat tttcctctct cgtaactaat
      781 aattttgaga gaggttt
//
LOCUS       DAVLHM010000113          662 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLHM010000113 DAVLHM010000000
VERSION     DAVLHM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.114"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..550
                     /locus_tag="VXE45_002143"
                     /pseudo
     CDS             1..550
                     /locus_tag="VXE45_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          221 a          121 c          121 g          199 t
ORIGIN      
        1 tactgacaat ccagacgctt atttgactga aatagcttct gaatttggct gtcatccaac
       61 taccatccac tatgcgctca aagctatggg ctacactcga aaaaaaagaa ccacacctac
      121 tatgaacaag agccagaaaa agtagcctta tttcttaaga attttaatag tttaaagcac
      181 ctagcacctg tttagattga tgaaacagga ttcgatactt atttttatcg agaatatggt
      241 cgctcattaa aaggtcagtt aataagaggc aaagtatctg gaagaagata tcagagaatt
      301 tctttggttg caggtctaac aaatgaatgg tgagttaatc gctccaatga cttacgaaga
      361 gacgatgacg agcgactttt ttgaagcttg gtttcagaag tttctcttac caacattaac
      421 cacaccatca gttattatta tggataatgc aagattccat agaatgggta agttagaact
      481 cttgtgtgaa gagtttgggt ataaactttt acctcttcct ccctactcac ctgagtacaa
      541 tcctattgag gctctataat atttgtagtg ggtaaatccc ctatggatat tatggagcct
      601 atttttgtgt agaaaaaaag tcccataaga tctataatga aaagcgatca aacaactcat
      661 ta
//
LOCUS       DAVLHM010000114          642 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLHM010000114 DAVLHM010000000
VERSION     DAVLHM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.115"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            105..584
                     /locus_tag="VXE45_002144"
     CDS             105..584
                     /locus_tag="VXE45_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0790078.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          242 a           82 c          149 g          169 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagctc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgtgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctaggaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa ag
//
LOCUS       DAVLHM010000115          541 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLHM010000115 DAVLHM010000000
VERSION     DAVLHM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.116"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            337..>541
                     /locus_tag="VXE45_002145"
     CDS             337..>541
                     /locus_tag="VXE45_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0790079.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVI"
BASE COUNT          207 a           59 c           95 g          180 t
ORIGIN      
        1 gacaaatcaa tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac
       61 tattctagtt tcaatatact atattatcgc ttaccaatat ttgcttttat atttgctaaa
      121 ctttcagaaa aaaagttgga gtatatgatg ctaggtgact gcgtcatgtt agtaaacgaa
      181 atggaaataa ctgatcatag agtagataac ttatttgaaa aagggaaaaa tgagataaaa
      241 gattcaattg gtacaaatag tgttttaaat aaaaaaatta ttttacaaaa aatcagaaaa
      301 ttatctaatc aaccgagtgg gtactggata ggttcgttgg atgagagatt tttagaccat
      361 gctattatta atcaaataga tgttactagt gaacaaattg ttttaatgag cgatggcttt
      421 tatgaattct atcaaaataa tcaaaataaa acttttgaag agttaattaa gatgagattt
      481 aattcttctg ctattgatcc aatctatgga aagaaggatg atgcaagtat tctagtcatt
      541 g
//
LOCUS       DAVLHM010000116          438 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLHM010000116 DAVLHM010000000
VERSION     DAVLHM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.117"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            277..>438
                     /locus_tag="VXE45_002146"
     rRNA            277..>438
                     /locus_tag="VXE45_002146"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a           72 c          114 g          100 t
ORIGIN      
        1 acgggttcga atcccgtacg gactatggta tgttgcggtt ggaacacttg atgaaaaaaa
       61 gtttaaaaaa acttaaaaat cttcaaaaaa gtgttgacaa gcgaaagcag ttgtgatata
      121 ctaatatagt tgtcgcttga gagaagcaag tgacaaagac ctttgaaaac tgaacaagac
      181 gaaccaatgt gcagggcgct acaacataag ttgtagtact gaacaatgaa aaaacaataa
      241 atctgtcagt gacagaaatg agtgagaact caaactttta atgagagttt gatcctggct
      301 caggacgaac gctggcggcg tgcctaatac atgcaagtag aacgctgaag gaggagcttg
      361 cttctctgga tgagttgcga acgggtgagt aacgcgtagg taacctgcct ggtagcgggg
      421 gataactatt ggaaacga
//
LOCUS       DAVLHM010000117          383 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037444
            SAMN33606996-rid17953023.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLHM010000117 DAVLHM010000000
VERSION     DAVLHM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606996
            Sequence Read Archive: SRR23725955
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721832.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721832.1
            Genome Coverage       :: 174x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:07:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,147
            CDSs (total)                      :: 2,098
            Genes (coding)                    :: 1,963
            CDSs (with protein)               :: 1,963
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 70 of 135
            Pseudo Genes (incomplete)         :: 59 of 135
            Pseudo Genes (internal stop)      :: 40 of 135
            Pseudo Genes (multiple problems)  :: 27 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606996-rid17953023.denovo.118"
                     /strain="AUSMDU00037444"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>383)
                     /locus_tag="VXE45_002147"
     CDS             complement(<1..>383)
                     /locus_tag="VXE45_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0790080.1"
                     /translation="STVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDN
                     LNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDR
                     FHIIQHLSRAMSRFRVQIMNQFERKS"
BASE COUNT          131 a           71 c           77 g          104 t
ORIGIN      
        1 gattttcgtt caaactgatt cataatttga acacgaaaac gactcatggc acggctgaga
       61 tgttggataa tatggaaacg atctagaacg attttagcac acggaaaaag ctgtttagcc
      121 aagtcatagt aaggactaaa catatccatc gtaatgattt tcacttgaca acgaacggct
      181 ctatcgtagc gaagaaagtg atttcggatg acagcttgtg ttctgccttc aagaacagtg
      241 ataatattaa gattatcaaa atcttgcgca atgaaactca tctttccctt agtgaaggca
      301 tactcatccc aagacataat ctttggaagc cgagaaaaat catgctcaaa gtgaaagtca
      361 ttgagcttgc gaatgacagt tga
//
